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The data obtained suggest the presence of acquired maturation abnormalities in the B cell compartment.
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We report a fatal case of toxic epidermal necrolysis (TEN) resulting from a high dose of cytosine arabinoside (ARA-C).
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Priapism associated with thrombophilia is a well-recognized entity.
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About 44% of the patients had gastric adenocarcinoma, and 82% had received mitomycin C.
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Histologic examination of tubular bones showed hyperostosis presumably due to prostaglandin-induced rapid formation of primitive bone.
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The authors present an elderly patient with mixed dementia who developed TD at multiple sites, (including respiratory dyskinesia [RD], limb dyskinesia, and orofacial dyskinesia) following abrupt withdrawal of risperidone therapy.
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Multiple pancreatic abscesses due to Candida albicans following ERCP.
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Open-lung biopsy revealed grade 2 lymphocytic bronchiolitis, the pathologic and immunologic correlate of acute pulmonary GVHD.
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If these patients are switched to alternative levothyroxine products, it is recommended that thyroid function tests be repeated after equilibration to the new product.
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BACKGROUND: Interferon (IFN)-associated retinopathy is typically characterized by retinal hemorrhages and cotton wool spots at the posterior fundus, but visual function is usually maintained.
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It is a potentially serious reaction which is little influenced by which drug is injected.
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The effect of potassium is reminiscent of its effect in the channelopathies underlying hypokalemic periodic paralysis, and the resistance to lidocaine applied peripherally suggests a peripheral sensory localization to the abnormality.
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One of the most troublesome side effects of perfusion is peripheral nerve damage, which has been reported at a rate of between 1 and 48% of perfused patients.
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Four weeks earlier she had developed hepatopathy during a regimen of carbamazepine, lynestrenol and sodium valproate.
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OBJECTIVE: To report the clinical course of a woman with cryptococcal meningitis and no previous cardiac disease who developed a fatal cardiac arrhythmia after an acute overdose of amphotericin B and to review its toxicity.
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PATIENT AND METHOD: A 34-year-old woman with chronic hepatitis C, genotype 3, receiving pegylated interferon alpha-2a and ribavirin for 6 months, developed progressive malaise and anemia 6 months after the end of treatment.
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The cerebral venous sinus thrombosis, involving cerebral veins, superior sagittal sinus and straight sinus, was diagnosed by cerebral angiography.
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This case represented the acute tumor lysis syndrome that occurred after chemotherapy of breast carcinoma.
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Spontaneous pneumothorax following chemotherapy for metastatic germ cell tumor: a case report.
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We report the first biopsy confirmed occurrence of acute interstitial nephritis in a patient receiving treatment with Sunitinib for metastatic renal cell cancer.
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The low frequency HAR wave persisted for the subsequent 3 months until a tingling sensation returned to the left leg.
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Oral warfarin is the standard of care for patients requiring long-term anticoagulation due to venous thromboembolic disease.
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RESULTS: Patient was found to have inferonasal nodular scleritis.
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The third patient had been suffering from serious akathisia while on risperidone, and was cured after switching to olanzapine, but thereafter the patient suffered from RLS at nighttime.
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Gynecomastia developed in two epileptic patients some months after the addition of oral fluoresone 750 mg daily to the phenobarbital and phenytoin already being administered.
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MRI also indicated improvement.
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Abnormalities of the pupil and visual-evoked potential in quinine amblyopia.
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Reperfusion was achieved by coronary thrombolytic therapy with urokinase.
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RESULTS: A literature search of publication between 1999 and October 2008 retrieved 34 cases of hepatitis.
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Transient hemiparesis caused by phenytoin toxicity.
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Antibody therapy is capable of permanently abolishing the signs of symptoms of digitalis poisoning after a matter of hours.
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A characteristic speech disorder, which may be described as cortical dysarthria or speech apraxia, occurs in approximately 1% of adults undergoing OLT.
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Removal of gadolinium by peritoneal dialysis.
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After 2 months, visual acuity and ocular hyperemia returned to baseline levels.
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This case suggests that highly angiogenic tumours such as angiosarcoma may be effectively palliated using agents usually reserved for refractory Wilms' tumour, and supports the view that adult Wilms' tumour is more sensitive to such agents.
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The most common side effects associated with amifostine are nausea, vomiting, hypotension, hypocalcemia and allergic reactions.
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Our observations suggest a new model for metabolic encephalopathy studies and provide insight into the mechanisms of pigmentary retinopathy.
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These cases suggest that marked acid reduction may predispose to esophageal candidial infection.
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Effects of highly overdosed indomethacin in a preterm infant with symptomatic patent ductus arteriosus.
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This study is based on the neuropathological and systemic findings among 225 liver, 101 heart, 40 lung, 28 heart-lung, 74 kidney and 32 bone marrow transplants.
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Epstein-Barr virus-associated lymphoproliferative disorder in a patient with rheumatoid arthritis on methotrexate and rofecoxib: idiosyncratic reaction or pharmacogenetics?
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During the first day of infusion, she began having severe shortness of breath.
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An apparent breed susceptibility of Collie dogs was observed.
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One patient received a total of four injections in the right eye and three injections in the left eye.
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Transient anuria following administration of angiotensin I-converting enzyme inhibitor (SQ 14225) in a patient with renal artery stenosis of the solitary kidney successfully treated with renal autotransplantation.
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CONCLUSION: It is important to elucidate the precise nature of new onset hearing loss in patients receiving iron chelation therapy, in order to avoid unnecessary cessation of much needed medication, on the assumption of ototoxicity.
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Prospective, controlled trials are warranted to further define the optimal dose, toxicity and potential role of cidofovir in renal transplant recipients with BK virus nephropathy.
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Rifampin can be associated with severe adverse effects such as hepatitis, acute renal failure, hemolytic anemia, and thrombocytopenia.
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A 49-year-old man with Crohn's disease treated with prednisone and mesalamine (5-ASA) developed worsening respiratory distress and fever.
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This finding suggests that fluvoxamine can precipitate Schneiderian first-rank symptoms in some susceptible patients.
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We report a case of interstitial pneumonitis induced by bicalutamide and/or leuprorelin acetate given as therapy for prostate cancer, in which the pneumonitis was successfully managed by steroid treatment.
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The patient presented with severe bladder pain, fever, and eosinophilia several hours after instillation.
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Liver disease induced by perhexiline maleate.
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An 80-year-old man with bilateral basal ganglia bleeding was unable to swallow safely and required tube feeding.
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IOP control had been poor prior to the laser-treatment, and did not appear to be more following treatment.
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Patients were reviewed at intervals of 2-4 weeks for 12 months.
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Two months later repeat colonoscopy with biopsies showed no evidence of collagenous colitis.
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The serum concentration of AZ was elevated to a maximum of 76.5 mg/ml.
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Those side effects that occurred, predominantly iron deficiencies, hypertension, and hyperkalemia, were controlled by appropriate clinical management.
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Trichosporonosis appears to be an emerging fungal infection among immunocompromised individuals (including both hematological and solid organ transplant recipients).
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The pregnancy was terminated, and she delivered at 27 weeks' gestation.
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The use of outpatient dobutamine infusions by a small, portable infusion pump in 3 patients with intractable congestive heart failure (CHF) is described.
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Painful neutrophilic skin lesions were observed in two children receiving granulocyte colony-stimulating factor (G-CSF) for treatment of idiopathic neutropenia.
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After the addition of citalopram, a desmethylclomipramine plasma level increase and an 8-hydroacy-desmethylclomipramine plasma level decrease were observed.
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Type I second-degree AV block (Mobitz type I, Wenckebach AV block) during ritodrine therapy for preterm labor.
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INTRODUCTION: Although gefitinib used for the treatment of non-small-cell lung cancer is a well-known cause of interstitial lung disease (ILD), few case reports on erlotinib-induced ILD have been issued.
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OBSERVATIONS: We observed aggravation and spreading of a psoriatic plaque when treated topically with the toll-like receptor (TLR) 7 agonist imiquimod.
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We present a case of disseminated histoplasmosis, complicated by retroperitoneal bleeding and leading to death, in a patient who was receiving systemic immunosuppressive therapy for rheumatoid arthritis and who was enrolled in a gene-therapy trial.
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Use of midodrine (Gutron) to treat permanent hypotension in a chronic hemodialysis patient.
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A 36-year-old man being treated with cisplatinum, vinblastine, and bleomycin for testicular carcinoma developed a dense left homonymous hemianopsia, encephalopathy, and a partial nondominant parietal lobe syndrome.
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Behavioral side effects associated with clonazepam may include agitation, aggression, hyperactivity, irritability, property destruction, and temper tantrums.
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This supports the well-reported potential of bleomycin to trigger acral vascular toxicity.
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Careful clinical and hematological monitoring should be performed, especially for the first 3 months, in patients beginning treatment with Pentasa.
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Leflunomide was stopped.
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Comedication included N-acetylcysteine, atenolol, and isradipine.
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Sirolimus has been widely used in renal transplantation, and its use in heart transplantation is increasing.
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In two patients clozapine was reinstated after risperidone was discontinued; serum triglyceride levels increased.
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We report a rare case of patient with dermatomyositis (DM) who developed spontaneous pneumomediastinum (PnM) and subcutaneous emphysema.
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Before ICU admission, the patient had suffered from painful mucositis causing severe dysphagia and bleeding, which was thought to be the result of chemotherapy.
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An 86-year-old African-American man presented with tonic-clonic seizures.
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Endocrinologically speaking, three of them had "Hashitoxicosis", while the other had silent lymphocytic thyroiditis.
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A 58-year old man was admitted to the hospital because of melena.
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The observed alterations of the thyroid gland were caused by a long lasting Wolff-Chaikoff effect with a delayed adaptation to high iodide concentrations.
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CASE SUMMARIES: While conducting a protocol evaluating the efficacy of intraperitoneal cisplatin and hyperthermia in the treatment of recurrent ovarian cancer, 3 patients were noted to exhibit anaphylactoid reactions.
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We report of a 42-year-old man, in whom pyomyositis developed while he was receiving the standard chemotherapy for T-cell non-Hodgkin's lymphoma (NHL).
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When the acute manic state is characterized by marked psychotic symptoms and intense anxiety, it may be associated with increased vulnerability to the development of severe lithium neurotoxicity.
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This report describes a case of flucytosine-associated ulcerating enteritis in which the small bowel x-ray demonstrated severe luminal narrowing, ulceration, and marked separation of loops of bowel.
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These results emphasise the difficulty of stimulating this mesencephalic region.
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A 71-year-old man, who had a history of a previous bullous drug reaction to a sulfonamide, began receiving an ophthalmic preparation that contained sulfacetamide sodium.
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Clevudine myopathy in patients with chronic hepatitis B.
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The patient has since returned to his routines of daily living and has reported no fatigue or other lingering adverse symptoms.
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Although thiazide-induced photosensitivity is a well-documented phenomenon, there have been no histologically proven cases of a lichenoid eruption in light exposed areas in the recent literature.
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Accidental overdose of multiple chemotherapeutic agents.
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SUMMARY OF BACKGROUND DATA: Meningiomas are known to enlarge in response to female sex hormones.
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Clinicians should be aware of fasting hypoglycemia as an unusual but potentially serious complication of disopyramide therapy.
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The patient was treated with mesalamine and prednisolone, and a repeat colonoscopy revealed an improvement in his bowel disease.
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We concluded that the colonic ulcer and the sigmoidovesical fistula had been caused by the administration of calcium polystyrene sulfonate and sorbitol.
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This report suggests that, like immunoblastic sarcoma, lymphomatoid granulomatosis may develop under conditions of diminished immunologic surveillance, whether iatrogenic or naturally occurring.
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The patient's symptoms resolved with oral vancomycin and his stool C. difficile toxin became negative.
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These findings are consistent with the assumption that long-term corticosteroid administration potentially induces not only myopathy but also motor neuron involvement as in mitochondrial diseases.
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