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We report a case of MALA in which acute renal failure resulting from dehydration secondary to diarrhea and poor oral intake likely caused MALA.
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The day after clozapine was stopped, while he was still receiving clomipramine 150 mg/d, he began behaving oddly, started sweating profusely, shivering, and became tremulous, agitated, and confused.
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CONCLUSIONS: These findings suggest that, in patients who are susceptible, the periocular or systemic absorption of inhaled corticosteroids may be sufficient to produce CSC in humans, supporting previous hypotheses regarding the pathogenesis of the disorder.
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OBJECTIVE: 1) To describe a patient with rheumatoid arthritis receiving adalimumab who developed fever, pancytopenia, splenomegaly, and extreme hyperferritinemia.
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We report a bacterial corneal ulcer that occurred in a patient who had worn extended-wear rigid gas-permeable contact lenses on a 1-week cycle for 9 months.
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We report a case of a previously healthy, postmenopausal woman who developed anticonvulsant hypersensitivity syndrome while taking Bellamine S (belladonna alkaloids; ergotamine; phenobarbital) for hot flashes.
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He was treated with penicillin.
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We report a case of intrathecal methotrexate neurotoxicity manifesting as left arm weakness and aphasia.
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Although other nitrites induce methemoglobinemia, exposure to methyl nitrite during phenylpropanolamine production appears to be a new cause of occupational methemoglobinemia.
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Glucagon is considered the drug of choice for treating bradycardia and hypotension encountered during beta-blocker poisoning.
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Erythromycin is a macrolide antibiotic that may increase the risk of lovastatin-induced rhabdomyolysis.
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The findings were judged to be consistent with soft-tissue injury associated with intravenous administration of phenytoin, also termed purple glove syndrome.
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On two occasions, within 48 hours of treatment, the patient developed acute leukopenia.
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CONCLUSION: Fungal infection of ICDs is a rare but serious complication of device implantation that must be treated aggressively with complete hardware explantation and prolonged antifungal therapy.
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Electroconvulsive therapy in myasthenia gravis.
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The patient was discharged from hospital after 120 days with normal liver function and recovered bone marrow.
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The authors report five cases of tremor related to itraconazole therapy, which occurred within 1-12 months of initiating treatment and resolved gradually following itraconazole withdrawal.
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We describe a case of clozapine-induced seizures in a patient with treatment-resistant schizophrenia.
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Internists will need to be increasingly aware of and prepared for this pharmacologic complication.
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The temporal and dose-response relationships suggested a possible association between the depressive symptoms and corticosteroid.
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Recently, the patient has exhibited signs of tardive dyskinesia.
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New strategies must include the development of completely fibrin-specific thrombolytics and drugs that may rapidly reverse the systemic and local clotting disorder.
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Prednisone doses of 1 mg/kg/d have been suggested.
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A patient with an allergy to a macrolide antibiotic was given tacrolimus and developed a sudden cutaneous reaction.
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BACKGROUND: Methotrexate (MTX) is a folic acid antagonist used in high doses as adjuvant chemotherapy for osteosarcoma.
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A drug addict with staphylococcal endocarditis treated with methicillin, who developed massive proteinuria and acute nephritic syndrome is described.
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After initial stabilization, the patient was discharged with warfarin (target INR = 2.5-3.5) together with beta-blockers, statins and metformin.
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However, several case reports have suggested that clozapine could also cause TD.
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Sequencing studies revealed the presence of mutations in viral isolates obtained after clinical resistance was observed.
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TSH levels were normalised with the addition of mouse serum to the patient's sample, confirming the presence of human anti-mouse antibodies as the interfering substance in the TSH assay.
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Thus, even after a long hiatus, it may not be safe to exceed the recommended maximum cumulative dose level of adriamycin.
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Lithium was withdrawn in each case.
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Skin manifestations of a case of phenylbutazone-induced serum sickness-like reactions.
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The 69-year-old patients recovered rapidly after oral administration of fluids and sodium bicarbonate.
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A second patient with a similar glucose tolerance test result showed postprandial hyperglycemia when treated similarly with betamethasone valerate cream 0.1%.
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The complete recovery from anagen effluvium is difficult to explain, but it could have been because of the early initiation of corticosteroid.
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Both patients with NMS had been treated with neuroleptics, including CYP2D6 substrates.
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However, this aggressive chemotherapy has not offered any advantage because of an unacceptably high treatment-related morbidity and mortality (17%).
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Adjuvant corticosteroid sparing therapy can also be associated with significant morbidity.
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Six days after taking erlotinib, a chest radiograph showed rapid progression of reticular infiltration in both lung fields.
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Nasal septal perforation in a patient with allergic bronchopulmonary aspergillosis and rhinitis on long term corticosteroids.
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We report five paediatric cases of portal vein thrombosis (PVT) occurring during chemotherapy, observed in two institutions over an 8-year time period.
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Little attention has been paid to infertility in men with epilepsy and little information exists about the mechanisms by which anti-epileptic drugs affect spermatogenesis or sperm function.
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We present a case of a 58-year-old female patient with Graves' disease who developed AA in the third exposure to methimazole (MMI).
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Acetazolamide (Diamox) is a carbonic anhydrase inhibitor commonly used in patients with glaucoma in order to reduce intraocular pressure.
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Even after a strict warning, he took another quinine tablet that evening, which triggered his fifth episode of severe thrombocytopenia, and confirmed the etiology of quinine-induced thrombocytopenia.
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In conclusion, the diagnosis of aflatoxicosis takes cognisance of geographical location, past events, staple diet and clinical features to exclude other infections.
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Lichen planus and acne provoked by gold.
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Follow-up ranged from 3 to to15 months.
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CASE REPORT: A 67-year-old female presented with acquired long QT interval syndrome with a refractory ventricular arrhythmia.
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We report a male patient with advanced AIDS who developed hypercalcemia 2 weeks after institution of rhGH therapy.
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Herein, we report the case of a 73-year-old woman who underwent major coronary surgery and developed fatal systemic venous thrombosis after recombinant factor VIIa was used in an attempt to control her severe postoperative bleeding.
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Diagnostic imaging showed restricted diffusion and fluid-attenuated inversion recovery imaging findings were normal at presentation.
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Acute renal failure is a rare complication following the administration of intravenous immunoglobulin (IVIG).
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Donepezil in the treatment of opioid-induced sedation: report of six cases.
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Although studies have shown a relationship between abnormal scapular motion and subacromial impingement, it has been unclear whether the altered scapular biomechanics represent a cause, or consequence, of impingement.
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Elevated levels of ammonemia, gamma-glutamyl transpeptidase, alkaline phosphatase and IgA were detected.
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Despite these measures he appeared to have progressive lymphoma.
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This report describes a unique path of spread of testicular cancer which also appears to spontaneously mature at the metastatic site.
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Managing ergot-induced gangrene: the anesthesiologist as a key player.
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Since early symptoms of the toxic effects of theophylline can mimic peptic ulcer disease, cimetidine might be prescribed for the gastrointestinal symptoms with subsequent worsening of theophylline poisoning.
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Mequitazine seemed to play a part similar to chlorpromazine, and absence of mequitazine-induced photosensitivity may be due to a relatively low dosage of the drug.
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The patient could be disconnected from the ventilator and within <24 h was extubated.
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Metformin-associated lactic acidosis (MALA) is a serious metabolic complication that occurs because of metformin accumulation in patients who become dehydrated or developed acute renal failure.
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We report a case with chronic hepatitis C (CHC) who developed sarcoidosis after the treatment by interferon alpha and ribavirin.
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Sonographically guided percutaneous thrombin injection is a minimally invasive and highly successful treatment of arterial pseudoaneurysms.
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The aim was to determine the source of the recurrent lesion based on its morphology and the patient's verbal history.
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Coexistence of hereditary angioedema and Turner's syndrome.
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After the addition of citalopram, a desmethylclomipramine plasma level increase and an 8-hydroacy-desmethylclomipramine plasma level decrease were observed.
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Intracranial hemorrhage and focal seizures secondary to use of L-asparaginase during induction therapy of acute lymphocytic leukemia.
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He was taken to surgery 8 days after cefazolin was discontinued and received perioperative prophylaxis with cefoxitin (total dose 3 g).
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PURPOSE: The case of a patient who developed aseptic meningitis, hemolytic anemia, hepatitis, and orthostatic hypotension simultaneously during treatment with trimethoprim-sulfamethoxazole is described.
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When managing TLS in infancy, clinicians must consider the relative degree of renal immaturity and its predisposition toward metabolic derangements.
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The patient had been receiving factor VIII:C clotting factor concentrates (mean 60,000 U/year) since 1975.
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The patient developed occipital infarcts and was found to have extremely elevated levels of PPA in his blood and dialysis fluid.
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This is a report of a renal transplant patient with Pneumocystis pneumonia who developed chemical cellulitis and ulceration following the extravasation of intravenous pentamidine into the soft tissues of the left hand and forearm.
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Depigmentation has been described with local steroid injections for other dermatologic conditions, but has not been reported previously with treatment of infantile ocular adnexal hemangiomas.
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She was placed on adjuvant Adriamycin (doxorubicin) chemotherapy, but 6 months later died of Adriamycin toxicity.
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The patient expired 13 d after admission.
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He presented with multiple masses in the right lobe of the liver and a metastasis in the left adrenal gland.
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In addition, ethambutol rarely causes visual loss during the early period or when given at lower doses.
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Polymerase chain reaction analysis of the serum showed dramatic decreases in the viral DNA copy number and revealed large viral concentrations prior to the skin manifestations.
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RESULTS: The material from inside the lumen of the catheter was analyzed using x-ray spectroscopy and a scanning electron microscopy.
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Pulmonary function test showed a mild restriction.
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We report a myeloma patient who developed severe paralytic ileus during bortezomib therapy, which presented in the context of progressive constipation without other known causes and which regressed promptly with medical management after drug cessation, suggesting a direct causal relationship.
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The purpose of this review is to increase awareness among physicians and other health care professionals that DIC may be a rare but potentially severe complication of anti-D IGIV treatment.
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Therapy with IFN-alpha may be associated with a number of neuropsychiatric symptoms, such as Parkinsonism, akathisia, seizure, and depressive disorders.
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We report a case of a patient with mild chronic renal insufficiency who had been taking simvastatin for over a year and developed acute weakness within 3 weeks after the start of treatment with colchicine for acute gouty bursitis.
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Seven patients with rheumatoid disease were given the iron-chelating drug desferrioxamine (DFX) to evaluate its possible anti-inflammatory effects.
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We postulate that the bolus of sulprostone resulted in possible coronary spasm that resulted in cardiac arrest.
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Its diagnosis is critical to avoid future exposure to aromatic anticonvulsants.
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Five months later, he presented with watery diarrhea and abdominal distention.
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In a review of the literature no report of a similar case was found.
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Three of 50 patients treated with isotretinoin (1 mg/kg/day) for cystic acne complained of poor night vision and/or excessive glare sensitivity.
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This represents the first reported case of syphilitic meningitis in a lupus patient.
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Clinicians should be aware of this potential adverse effect of tigecycline.
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Follow-up brain MRI of these 2 patients revealed that the lesions in the thalamus and brainstem disappeared or resolved almost completely.
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Cephalexin rash in infectious mononucleosis.
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In both patients seizures were associated with discontinuation of short-term agents with high antimuscarinic properties.
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The exact mechanism of IVIG-associated acute renal failure remains unclear.
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