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A toxic encephalopathy characterized by depressed level of consciousness, marked irritability, and ataxia developed in seven children, 5 years of age and younger, following administration of an antiemetic combination of pentobarbital and pyrilamine maleate.
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Delayed pancreatic pseudocyst formations.
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Central serous chorioretinopathy developed in 2 cases of retrobulbar neuritis during systemic treatment with corticosteroids.
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Patients should be informed about the risk of osteonecrosis when taking dexamethasone as an antiemetic drug.
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The authors describe a case of combined lithium and haloperidol toxicity characterized by hyperpyrexia, severe rigidity, mutism, and development of irreversible tardive dyskinesia.
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CASE SUMMARY: A 21-year-old African American male with schizophrenia came to our medical intensive care unit from the crisis intervention unit (CIU).
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One other case of tocolysis-induced vulvar edema has been reported, as have five cases of postpartum vulvar edema, associated with an 80% maternal mortality rate.
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The tacalcitol treatment was terminated, seven days later, the serum calcium level had returned to the reference range without any specific treatment.
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Therefore, patients on long-term therapy with atypical antipsychotic drugs should be screened periodically for TD.
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The latter dialysate was prepared by adding sodium phosphate salts to the "base concentrate" of a dual-concentrate, bicarbonate-based dialysate delivery system.
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We report a 16-year-old male who developed nephrotic syndrome related to membranous glomerulopathy with clinical and serological evidence of systemic lupus erythematosus after treatment with griseofulvin.
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Recently, the use of octreotide has been described as an alternative treatment in these patients.
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Heparin sodium is routinely used in the prophylaxis against deep venous thrombosis in medical and surgical patients.
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Eosinophil infiltration is a characteristic feature of nasal polyps associated with AIA.
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Based on the clinical status of the patient, it was suspected that several conditions contributed to the abnormal hypersensitivity to warfarin.
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Venlafaxine-induced urinary incontinence resolved after switching to sertraline.
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The degree of clinical recovery related to maximal disability.
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Acute septic arthritis in chronic osteonecrosis of the hip.
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He received the full course chemotherapy but without a significant regression.
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Three of the four patients also had bilateral ptosis.
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Rechallenge resulted in the same drug rash.
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Infiltrates, hemorrhages and macular edema present preoperatively dissolved over a period of six months.
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Cardial and respiratory function was compromised and intubation was necessary.
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During her hospital stay, her sodium level and serum osmolality increased and her urine osmolality decreased, whereas her lithium levels remained within normal limits.
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A 27-year-old man who had a history of bronchial asthma, eosinophilic enteritis, and eosinophilic pneumonia presented with fever, skin eruptions, cervical lymphadenopathy, hepatosplenomegaly, atypical lymphocytosis, and eosinophilia two weeks after receiving trimethoprim (TMP)-sulfamethoxazole (SMX) treatment.
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We describe two women who developed HUS after MMC therapy and presented massive pulmonary bleeding.
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After bilateral implantation of an angle-supported anterior chamber intraocular lens (AC IOL) in an allergic patient, the haptic tips were exposed through the limbus in the left eye.
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Although gabapentin withdrawal has been previously reported and usually consists of anxiety, diaphoresis, and palpitations, this is the first reported patient with generalized seizures and status epilepticus secondary to gabapentin withdrawal.
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Prolongation of the QT interval and ventricular tachyarrhymias have been described in patients on amiodarone therapy.
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Patients who present to the Emergency Department after ingestion of excessive amounts of suflonylurea medications often have hypoglycemia refractory to dextrose administration.
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We describe a patient with a liver abscess due to Entamoeba histolytica, in whom metronidazole therapy (total dose, 21 g over 14 days) was complicated by reversible deafness, tinnitus, and ataxia and who relapsed 5 months later with a splenic abscess.
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Endovascular treatment of renal artery thrombosis caused by umbilical artery catheterization.
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CASE PRESENTATION: We report a patient with CF who developed recurrent eosinophilia and severe persistent bronchospasm following repeated administration of preservative-free tobramycin by inhalation, beginning at 16 months of age.
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We present the case of a postictal patient with lethargy, hyperammonemia, otherwise normal liver function tests, and a therapeutic valproic acid level.
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In this case of CPM, blindness was encountered and was thought to be "hysterical." The blindness went away after four months.
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As an insoluble steroid aerosol, beclomethasone diproprionate was recently made available in the United States.
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Power spectrum analysis studies revealed that heart rate had significantly improved and that power spectrum cardiovascular parameters had returned to normal.
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The present study describes a patient who had unusual weight fluctuation under corticosteroid and psychotropic treatment such as mianserin and aripiprazole.
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Recognition of amifostine as the cause of this adverse event may prevent the cost and inconvenience of a hospital admission.
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We report here the case of a 10-year-old male child with primary steroid-resistant nephrotic syndrome who was non-responsive to steroids and cyclophosphamide.
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Merkel cell carcinoma after liver transplantation: a case report.
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We discuss a variety of bronchopulmonary complications of IBD and their association with sulfasalazine.
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All of the studies were carried out at the University of Pittsburgh Medical Center, Department of Pathology, Neuropathology Division.
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Published data on the use of vitamin D for prophylaxis or treatment of any form of osteoporosis fail to document benefits superior to those of calcium alone or calcium with estrogens and fluoride.
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After discontinuation of the drug, plasmapheresis and steroid therapy led to a sustained remission.
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Nicotinic acid-induced fulminant hepatic failure.
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Additional typical findings were the high excretion of adipic acid, suberic acid, and 4-octen-1,8-dicarboxylic acid demonstrating the enhanced capacity of omega-oxidation in fatty acid oxidation.
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Switching patients from olanzapine SOT to olanzapine ODT treatment resulted in significant weight loss that was maintained during 12 months in both case reports.
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Cardiac glycosides are thought to prevent doxorubicin cardiomyopathy by competitively inhibiting doxorubicin at its receptor sites, but ouabain has a much shorter half life than doxorubicin and its metabolites and so is less effective than digoxin.
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Screening for CMV infection in pregnant women receiving immunosuppressive drugs is recommended.
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The aetiology in this case is uncertain but it may have resulted from treatment with L-asparaginase or vincristine.
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The other patient had no hematoma and his course was dominated by esophageal rupture.
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The knee pain and swelling responded promptly to the institution of empirical broad-spectrum antibiotics.
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Management included successful treatment with a prolonged course of antibiotics, including ciprofloxacin, neurosurgical drainage and long-term immunoglobulin supplements.
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To the best of our knowledge, this is the first report of an association between sunitinib and gynaecomastia.
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Primary cutaneous T-cell lymphoma following organ transplantation in a 16-year-old boy.
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It also appears to be effective in other conditions such as psoriasis and ankylosing spondylitis.
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As physicians begin to treat chronic hepatitis C more often and more aggressively, this potential problem with occur more frequently.
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The patient' condition improved after rapid tapering of her epoprostenol and administration of corticosteroids.
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The typical fluoxetine-induced symptoms of restlessness, constant pacing, purposeless movements of the feet and legs, and marked anxiety were indistinguishable from those of neuroleptic-induced akathisia.
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The most common side effects associated with amifostine are nausea, vomiting, hypotension, hypocalcemia and allergic reactions.
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A case of congestive heart failure in a child with Wilms' tumor treated Adriamycin is presented and discussed.
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RESULTS: To date, 13 patients with chronic hepatitis B infection treated with TNF-alpha inhibitors have been reported: 11 with infliximab and 2 with etanercept.
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He presented symptoms of hemiparesis 3 days after the operation.
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Microangiopathic cytokines released in response to the GVHD and infection may damage the intima of microvessels that were previously injured by the two BMT.
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Serotonin syndrome in the perioperative period.
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Eight patients developed a total of 12 episodes of sudden, massive vitritis.
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Its aetiology is variable and it remains difficult to treat.
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Hyperinfection, an augmentation of the normal skin-lung-intestine life cycle, occurs in roughly two-thirds of infected transplant recipients, with dissemination in the remainder.
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OBJECTIVE: To report a case of ciprofloxacin-induced psychosis and to discuss occurrence rates, risk factors, possible etiologies, preventive measures, and treatment courses for this adverse reaction.
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All nine eyes had recurrence of the membranes after treatment terminated and required a maintenance regimen of corticosteroid eyedrops.
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We consider asterixis to be an easily overlooked sign of neurotoxicity, which may occur even at low or moderate dosage levels, if certain drugs as lithium or clozapine are used in combination with CBZ.
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No adverse reaction was observed from the intra-articular injections.
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Full recovery to pre-episode status of a quiet eye with clear vitreous was seen in all patients.
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Seizures were controlled by the anticonvulsive agent Dilantin (Pfizer, Khet Klongtoey, Bangkok) and she returned home without any permanent neurologic deficits.
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We observed 3 diabetic patients with intolerable dizziness followed by nausea and vomiting immediately after an initial administration of the alpha-glucosidase inhibitor, voglibose.
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Similar to reports in patients receiving gefitinib, those with pathologic findings of UIP on resected lung specimens or known pulmonary fibrosis may be at particular risk for erlotinib pulmonary toxicity.
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Similarities to dinitrochlorobenzene (DNCB) are pointed out.
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CONCLUSIONS: Mecamylamine at 2.5-6.25 mgm/day has no significant peripheral parasympathetic activity and may be safely taken long term (up to 550 days in this study).
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We report two cases of Methicillin-resistant Staphylococcus aureus (MRSA) prosthetic hip infections successfully treated with a long course of linezolid.
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In deciding if tamoxifen therapy is warranted, all potentially life-threatening adverse events associated with tamoxifen should be considered, including endometrial adenocarcinoma or uterine sarcoma.
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Although there is one case report of cholesterol crystal embolization following t-PA therapy with only extrarenal manifestations (N Engl J Med 321:1270, 1989), this is the first reported case of atheroembolic acute renal failure following t-PA therapy.
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Accidental ingestion and aspiration of hydrocarbons in children are common.
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A higher frequency than expected of HLA A 11 in three patients and B 15 in five patients was seen.
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The patient was given 14 mg of etomidate and 100 mg of succinylcholine intravenously.
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Progressive interstitial lung disease from prolonged methotrexate therapy.
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Optic neuropathy developed in a patient with rheumatoid arthritis who had been receiving D-penicillamine for about 1 year.
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Coexistence of chronic myelogenous leukemia and chronic lymphocytic leukemia.
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A careful and complete medication history can help avoid unnecessary discontinuation of clinically important medications and inadvertent rechallenge with the causative agent.
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PURPOSE: To report two cases of acute endophthalmitis following intravitreal bevacizumab injection.
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After receiving 3 doses of ifosfamide/mesna, she was found to be unresponsive.
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Embolization of a fragmented thrombus or/and attenuation of the lytic state leading to fresh embolization is/are the possible mechanism(s).
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We describe 2 patients with cutaneous lupus erythematosus who developed severe dapsone reaction after low dose therapy, with a fatal outcome in one.
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PURPOSE: Utilization of lead-contaminated opium may lead to severe motor neuron impairment and quadriplegia.
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Patients at increased risk could be identified.
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In two cases, death was believed to be a direct consequence of HUS.
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Sulfasalazine has been associated with bronchopulmonary complications of inflammatory bowel disease (IBD) in adults.
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An almost total breast reduction was performed; 5 kg of right breast tissue and 7 kg of left breast tissue were excised.
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ILP is an effective treatment in recurrence situations or where resection threatens loss of function; it, however, requires administration in specialized centers, progress in standardization and close monitoring to avoid locoregional toxicity, the mechanisms of which merit further investigation.
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An objective causality assessment revealed that the interaction was probable.
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