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Three hemodialyses were performed in the patient during the oliguric phase of the disease.
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The international literature regarding opportunistic infections after immunosuppressive therapy with alemtuzumab with particular attention on fungal infections has also been reviewed.
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Successful intraoperative use of recombinant tissue plasminogen activator during liver transplantation complicated by massive intracardiac/pulmonary thrombosis.
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All seven patients were receiving INH daily for tuberculosis (TB) prophylaxis.
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DISCUSSION: To our knowledge, this is the first case report illustrating neuralgic amyotrophy triggered by exposure to the antibiotics vancomycin, tobramycin, and piperacillin/tazobactam.
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The reason for this is discussed.
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Tacrolimus-induced HUS: an unusual cause of acute renal failure in nephrotic syndrome.
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This case demonstrates that localized signs of a bowel perforation may be absent in patients administered corticosteroids, that these patients may present with unusual, remote findings, and that bowel perforation can produce cervical subcutaneous emphysema.
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The mean age of onset is around puberty and boys suffer more commonly as they are more inclined to play video games.
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Two weeks later, the patient went to a local emergency department after experiencing two brief syncopal episodes.
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We report the case of an adult patient with acute lymphoblastic leukemia who presented with repeated transient ischemic attacks followed by a seizure during consolidation treatment with L-asparaginase.
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However, it failed in 1 case requiring transabdominal transperitoneal closure of the fistula with an interposition of omentum.
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On postoperative day 17, she demonstrated hyperkalaemia and metabolic acidosis; she was diagnosed to have hyperkalaemic distal RTA with aldosterone deficiency (type IV).
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We report a case of drug-induced pemphigus caused by an angiotensin-converting enzyme inhibitor, captopril.
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These observations add to the literature on pro-arrhythmic effects of commonly used antiarrhythmic drugs.
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This case of linezolid-associated acute interstitial nephritis within the context of a drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in a patient treated with linezolid raises concerns about the presumed renal safety of this drug.
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He suddenly developed a fever (temperature, 38 degrees C) and severe lower back pain without apparent cause.
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That review suggested that patients receiving anti-D IGIV be monitored for those and other potential complications of hemoglobinemia, particularly disseminated intravascular coagulation (DIC).
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In patients with cirrhosis, the metabolism of meperidine is decreased, leading to accumulation of the parent drug and possible CNS depressive effects similar to hepatic encephalopathy.
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After operation they developed arterial hypotension that failed to respond to epinephrine (adrenaline) or dobutamine treatment.
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Three years later, treatment with ampicillin caused another episode of cholestatic hepatitis with cholestasis and duct paucity on rebiopsy.
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DATA SYNTHESIS: Genetic deficiencies in DPD, the rate-limiting enzyme responsible for 5-FU catabolism, may occur in 3% or more of patients with cancer putting them at increased risk for unusually severe adverse reactions (e.g., diarrhea, stomatitis, mucositis, myelosuppression, neurotoxicity) to standard doses of 5-FU.
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Marrow aplasia lasted for 4 and 10 days, peripheral neuropathy for 15 and 42 days, gastrointestinal toxicity for 3 and 5 days, and hypertension for 5 and 14 days.
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This report suggests that careful monitoring of patients undergoing oral amiodarone loading is necessary.
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Methotrexate-associated nephropathy is a rare complication in pediatric oncology, and a review of the literature suggests that exposure to nephrotoxic agents may be a significant but perhaps underrecognized risk factor for its development.
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Retinoic acid syndrome in acute promyelocytic leukemia.
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Malignant hyperthermia: clinical course and metabolic changes in two patients.
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Toxic effects were less severe than previously described: this may be attributable to relatively low doses of DCF or to precautions taken to prevent tumour lysis syndrome.
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This article reviews case reports and clinical studies of thrombolysis during and shortly after CPR in order to estimate the risk of severe bleeding events caused by CPR in association with thrombolysis compared with CPR without thrombolysis.
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The relationship between this complication and calcium antagonist therapy is discussed and therapeutic strategies are presented.
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During her life the patient frequently presented catamenial MA attacks with an increasing frequency during pregnancy in particular in the second and third trimesters, and then during breast-feeding.
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In view of limited therapeutic options for her progressive disease, a trial of fluorouracil 300 mg/m(2)/d continuous intravenous infusion over 5 days was initiated without any premedications.
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Our case represents the second reported case that required surgical intervention for cure.
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DATA SYNTHESIS: A 49-year-old man developed symptoms of severe psychosis concomitant with ciprofloxacin (250 mg bid) treatment.
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The authors performed a literature search using PubMed and the search terms "gemcitabine" and "radiation recall" to find prior cases of radiation recall attributed to gemcitabine.
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An oral multivitamin tablet was substituted instead.
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Eighteen patients were given MMF for the following reasons: renal failure in nine (50%); treatment of acute rejection in three (16.6%); primary prophylaxis of rejection in five (27.7%); and CNI withdrawal in one (5.5%).
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A case of subepidermal autoimmune blistering disease in an 86-year-old woman is reported.
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MRI demonstrated an ischemic infarct in the right striatum.
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The main side-effects of Lp-TAE combined with HT were low-grade fever, localized pain, myelo-suppression and liver dysfunction, but these were transient and eventually disappeared.
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Results of all studies for Cushing's syndrome were normal and remained so 1 year later.
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The erythroid defect fully reversed after the drug was discontinued and could not be attributed to the patient's previously treated lung carcinoma.
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This case suggests that, when TMP/SMX is combined with glipizide, patients should be closely monitored, especially those at high risk for hypoglycemia.
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We report the occurrence of renal failure due to cholesterol crystal embolization following thrombolytic therapy with intravenous recombinant tissue-type plasminogen activator (t-PA).
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An aerobic exercise test demonstrated remarkable serum lactate elevation, which was attenuated by the administration of coenzyme Q10.
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Massive pulmonary thromboembolism resulted in circulatory collapse.
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While the true correlation remains unknown, allergic cross-reactivity may occur between sulfonamide antibiotics and non-antibiotics, such as loop diuretics.
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Treatment of lithium-induced diabetes insipidus with amiloride.
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Herpetic tracheobronchitis may be a commoner clinical syndrome than generally assumed.
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The pigment may be a drug metabolite-protein complex chelated with calcium, or an insoluble minocycline-melanin complex.
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CONCLUSION: This is the first report of keratitis caused by Nocardia exalbida.
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Imatinib mesylate-related fatal acute hepatic failure in a patient with chronic myeloid leukaemia and chronic hepatitis B infection.
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Patch testing with NSAIDs is useful for confirming clinical diagnoses of delayed hypersensitivity to these drugs.
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Whether these drugs adversely affect hepatobiliary scans is unknown.
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The child was treated with resin hemoperfusion (XAD-4) to reduce her serum chloramphenicol concentration.
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We report on three cases wherein treatment of dexmedetomidine-induced bradycardia with i.v. glycopyrrolate (5.0 microg/kg) not only resulting in resolution of bradycardia but also resulting in an exaggerated increase of arterial blood pressure.
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We suggest that the treatment of hypoglycaemia with 50% solution of dextrose is associated with a significant risk factor in those diabetic individuals who are either allergic or are receiving beta-adrenoreceptor blocking drugs.
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The identification of the spider as a brown recluse and the location of the bite over the nerve's usual pathway strongly suggest that the venom was responsible for this complication.
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Physical exam revealed a patient with aphasia, tremor, and an expressionless face, able to make eye contact and move all four extremities.
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CONCLUSION: Our PCR analysis showed the presence of CMV-DNA within the cornea of the patient with corneal endotheliitis.
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HMSN is diagnosed in most cases retrospectively, usually suggested by the observation of foot abnormalities or family history.
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The clinical aspect of porphyria has been investigated, and it is well known that porphyrinogens such as estrogens and alcohol or other inducers of P450 isoenzymes exacerbate the porphyric state.
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These findings are discussed in the context of the few previous reports and are particularly important for future genetic counselling.
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Treatment was continued for 6 days, during which the dosage was progressively decreased, and the mare was discharged.
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A 32-year-old man with a family history of type 2 diabetes mellitus presented with circulatory collapse and deep coma after 9 days of treatment with perospirone hydrochloride, a recently developed atypical antipsychotic agent available only in Japan.
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Severe chronic active Epstein-Barr virus infection mimicking steroid-dependent inflammatory bowel disease.
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His complete remission was maintained with a nitrosourea, nitrogen mustard and methotrexate for 3 years.
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Leishmaniasis: a rare cause of unexplained fever in a renal graft recipient.
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Epoprostenol may be associated rarely with severe erythroderma.
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A 12 year old patient with atrial flutter is presented, in whom intravenous adenosine was followed by acceleration of the heart rate to a potentially dangerous arrhythmia.
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CONCLUSION: Flecainide is an effective therapy for supraventricular tachycardias in a twin pregnancy.
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This was initially diagnosed as a spreading dental infection.
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A case of Kaposi's sarcoma following treatment of membranoproliferative glomerulonephritis and a review of the literature.
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Serotonin syndrome caused by interaction between citalopram and fentanyl.
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Moreover, when the deficit is recognized the epidural itself may be falsely blamed for postoperative paraplegia.
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The need for open-lung biopsy in patients with classic manifestations of LAM is also questioned, especially with the advent of high-resolution CT scanning, the nonspecificity of hormonal receptors with regard to response to therapy, and the possible need for subsequent lung transplantation.
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Three patients were weaned from the VADs, and two survived.
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Brain MRI showed restricted diffusion in the rostral midbrain and temporal and parietal lobes but not in the pons.
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Cessation of MTX therapy led to complete regression of the tumor.
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Cyclosporin side effects included hirsutism, hypertension, increased blood levels of urea and creatinine, and abnormalities in liver function tests.
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This was postulated to be due to the tacrolimus therapy, which was withdrawn.
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METHODS: The investigation included inhalation challenge with the suspected compound combined with monitoring of lung function tests and post-challenge bronchoalveolar lavage.
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A 21-year-old woman suffering from bipolar affective disorder developed systemic lupus erythematosus (SLE) with characteristic laboratory findings, 18 months after starting carbamazepine maintenance treatment.
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Schizophrenia-like psychosis caused by a metabolic disorder.
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OBJECTIVE: To report a case of phenolphthalein-induced toxic epidermal necrolysis (TEN) in a patient maintained on several other medications more commonly known to be associated with TEN.
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Sixteen patients with widely metastatic cancer of the breast, including one man, received mitoxantrone, 10 mg/m2 intravenously (IV) over 30 minutes on day 1, followed by cyclophosphamide, 200 mg/m2 by mouth (PO) daily in divided doses on days 3 to 6.
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Sirolimus-associated pneumonitis has been described in renal transplant patients.
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Cardiomyopathy after widely separated courses of adriamycin exacerbated by actinomycin-D and mithramycin.
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In this article lithium is not discussed, although there are a number of concerns about lithium's potential teratogenicity, and it has been implicated in Epstein's anomaly, a congenital heart defect among infants born to women taking lithium; as with other medications, however, the data have specific limitations.
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DLST is a good diagnostic tool for AZA allergy, especially for severe drug allergy cases.
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Fibrosis of corpus cavernosum after intracavernous injection of phentolamine/papaverine.
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CONCLUSION: It is important to maintain an awareness for the possible association between HIV lipodystrophy and symptomatic epidural lipomatosis.
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At 37 weeks of gestation, she spontaneously delivered a healthy male baby.
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Owing to suspected acute myocardial infarction, the patient was treated with thrombolytic therapy but her condition deteriorated.
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The findings from transbronchial lung biopsy and bronchoalveolar lavage (BAL) were consistent with an organizing diffuse alveolar damage pattern.
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Herbal medicine induced Stevens-Johnson syndrome: a case report.
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All these resolved on reducing the dosage of cyclosporin.
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A 64 year old man with recurrent metastatic squamous cell carcinoma of the head and neck developed severe skin rash and bone marrow aplasia 4 and 7 days, respectively, following a single dose of 40 mg/m2 methotrexate (MTX).
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We report on a 30-year-old man with metastatic non seminomatous germ cell tumor of the left testicle to the abdomen and the lungs, who suddenly developed a bilateral spontaneous pneumothorax after the first course of salvage chemotherapy.
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Serum gadolinium levels were measured 1 hour after the gadolinium administration, then at 24 and 48 hours after PD was initiated.
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