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Pharmacologic and psychotherapeutic issues in coexistent paranoid schizophrenia and narcolepsy: case report.
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Linezolid-associated acute interstitial nephritis and drug rash with eosinophilia and systemic symptoms (DRESS) syndrome.
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In order to prevent GVHD, CsA alone was administered, 3 mg/kg i.v. per day for a total of 40 days.
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These observations indicate that submassive hepatic necrosis may result from treatment with propylthiouracil and are consistent with the notion that sensitization mechanisms may be responsible for the hepatic injury induced by this drug.
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The mechanism of leukopenia is thought to be secondary to either an immune-mediated response or direct bone marrow toxicity.
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Reports of corticosteroid anaphylactic reactions are rare in the medical literature.
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It is suggested that the patient had sulfasalazine-induced lupus, which manifested with serositis and pulmonary parenchymal involvement in the absence of joint symptoms.
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A 51-yr-old nonsmoking male patient without any history of previous allergies, asthma, hay fever, or urticaria developed attacks of asthma when captopril was added to the nadolol and dyazide treatment for his high blood pressure.
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Ophthalmologic and neurologic findings in two children exposed to vigabatrin in utero.
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Fixed drug eruption in hands caused by omeprazole.
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A 14-year-old boy with chronic granulomatous disease and severe infection was admitted to the hospital because of left shoulder aspergillus' infection and pain.
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Pertinent literature was reviewed to provide supporting evidence for the mechanism and clinical implications of the drug interaction.
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We describe two dark-skinned patients who developed hyperpigmented skin and tongue lesions during combination therapy with IFN and ribavirin.
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This case study describes an atypical case of refractory, sodium warfarin-induced necrotizing fasciitis and myonecrosis.
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RESULTS: The patient with the primary perforation was managed conservatively, while the second was subjected to immediate surgical exploration.
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He now realised that he had eaten a chocolate cake before this episode and remembered that before the first episode he had had a chocolate mousse dessert.
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All of the patients responded with increased levels of Hb F, but the responses in total Hb varied.
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PATIENT AND METHODS: We report on a patient suffering from metastatic rectal cancer.
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Debris was probably flushed into the external carotid artery, and passed through an anastomosis into the ophthalmic artery, resulting in retinal artery embolization.
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Animal studies suggest central D2-type dopamine receptor stimulation and oxytocin release from the paraventricular nucleus of the hypothalamus mediate the effect.
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At 1 year of age cardiovascular and renal function is normal, but there is developmental delay.
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We report a case of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) secondary to trimethoprim-sulfamethoxazole (TMP-Sx) therapy for presumed community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infection.
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After the second course he developed persistent symptoms of nausea, vomiting, and pain.
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We report an unusual pattern of supravenous hyperpigmentation occurring after CHOP chemotherapy.
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Pneumonitis with pleural and pericardial effusion and neuropathy during amiodarone therapy.
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This suggests that trial chlormadinone acetate withdrawal in patients showing increasing levels of PSA during combined androgen blockade should be considered before initiation of alternative treatment.
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The first day after biopsy, the child developed gross hematuria and abdominal pain and an antibiotic was added to her treatment.
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Adverse reactions, however, are relatively common as well.
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Mechanisms for creating this effective host response need further investigation.
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He wore a retainer lens, rigid gas permeable lens, overnight for 2 months before the corneal ulcer occurred.
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The aim of this study is to draw attention to the adverse effects of henna, applied over the whole body, observed in glucose-6-phosphate dehydrogenase (G6PD) enzyme deficient siblings.
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An esophago-gastro-duodenal examination was performed which showed antritis and duodenitis consistent with radiation therapy.
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Divalproex sodium-induced eosinophilic pleural effusion.
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In 1 patient, leukoencephalopathy was progressive and irreversible brain damage and mental retardation persisted.
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Intravenous diazepam exacerbated the seizures.
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The possible mechanisms for this complication in out patient are discussed.
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Recurrent life-threatening episodes of ventricular tachycardia persisted despite maximal antiarrhythmic theraphy with amiodarone, metoprolol and mexiletine.
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Asthma is one of the most common chronic medical conditions.
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The recombinant human IgG1 monoclonal antibody specific for human TNF-a adalimumab (Humira) has been recently introduced for the treatment of moderate/severe psoriasis.
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His pulse rate was 90 min(-1) and his respiratory rate was 20 min(-1).
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Reflex vasospasm induced by the injection trauma may be etiologically involved.
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The principle treatment for DPD-deficient patients with severe acute 5-FU reactions is supportive care; however, the administration of thymidine potentially may reverse severe 5-FU-induced neurologic symptoms such as encephalopathy and coma.
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Trazodone therapy was continued or reinstated shortly after the hypomanic episode without further evidence of hypomania.
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Complete resolution of symptoms within 1-4 days was accompanied by normalization of ADC abnormalities.
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Drug discontinuation resulted in complete resolution of the clinical and radiographic picture.
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Secondary pancreatic involvement by diffuse large B-cell lymphoma presenting as acute pancreatitis: treatment and outcome.
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Patients reported a decrease in episodes of spontaneous sleeping during the day, fewer myoclonic twitches, improved daily function and greater social interaction.
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We present a patient who developed extensive Molluscum Contagiosum (MC) lesions shortly after being started on HAART.
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The total amount of vitamin K received from the enteral feedings ranged from 50 to 115 micrograms/day, which is less than the normal daily intake of 300 to 500 micrograms.
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Acute sensorineural hearing loss following intravenous ketoralac administration.
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Less common adverse events to dapsone include the idiosyncratic reactions of leukopenia and agranulocytosis, cutaneous eruptions, peripheral neuropathy, psychosis, toxic hepatitis, cholestatic jaundice, nephrotic syndrome, renal papillary necrosis, severe hypoalbuminemia without proteinuria, an infectious mononucleosis-like syndrome, and minor neurological and gastrointestinal complaints.
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CONCLUSION: We report herein the fifth case of visceral leishmaniasis in a patient under TNF-alpha therapy, and the first one, to our knowledge, presenting a consequent secondary macrophagic activation syndrome.
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We describe a patient with a liver abscess due to Entamoeba histolytica, in whom metronidazole therapy (total dose, 21 g over 14 days) was complicated by reversible deafness, tinnitus, and ataxia and who relapsed 5 months later with a splenic abscess.
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A 39-year-old female presented for elective bilateral thoracoscopic splanchnicectomy for chronic severe visceral pain.
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However, there remain questions concerning whether these drugs, especially methimazole (MMI), may be associated with aplasia cutis congenita (ACC) and how best to avoid impairment of fetal thyroid function during their use.
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The mirtazapine plasma-level was 368 ng/ml still after 41 hours.
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the disease has been described mainly in patients treated with systemic corticosteroids (39 cases out of the 71 reported cases) or local corticosteroids (3/71) and in patients suffering from Cushing's syndrome (7/71) but rarely in HIV-infected patients (3/71).
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In this paper we report a case of nimodipine overdosage resulting in prolonged hypotension and hypoxemia, which was successfully treated with calcium gluconate.
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We report a case of autoimmune hepatitis likely triggered by the use of black cohosh (Actaea racemosa), an agent marketed to treat menopause symptoms.
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Despite effective treatment with high-dose trimethoprim-sulfamethoxazole and steroids, morbidity is often severe and lethality remains high.
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Acute aflatoxicosis: case report.
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The third patient had dyspnea on exertion, unchanged over two months.
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Rapid liver failure related to chronic C hepatitis in an HIV seropositive hemophilic patient with severe immunodepression.
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Tetany in a child with AIDS receiving intravenous tobramycin.
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Before the introduction of anti-vascular endothelial growth factor (VEGF) drugs, photodynamic therapy (PDT) was used, with conflicting functional results.
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A biopsy taken from the lesional skin revealed dilatation of intraepidermal eccrine ducts and a spongy appearance in the corneal layer (Fig. 3).
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Symptoms and endoscopic lesions quickly regressed within 1 week of meloxicam withdrawal.
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Carbamazepine-induced hyperammonemia.
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In immunodeficiency conditions, unusual forms of leishmaniasis can develop and foster the risk of a diagnostic delay and of poor response to therapy.
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We describe the safety and efficacy of enfuvirtide therapy in 4 patients with severe hemophilia A.
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Terlipressin-induced ventricular arrhythmia.
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Acute lung injury associated with 5-fluorouracil and oxaliplatinum combined chemotherapy.
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A 3-year-old boy diagnosed with acute lymphoblastic leukemia received induction chemotherapy.
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The maximum tolerated single dose of intravenous iron infusion and iron pharmacokinetics are not known in children and not clear in adults.
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We report a heart-lung transplant patient who developed chronic rejection (BOS stage 3) with the appearance of gross bronchiectasis on a spiral computed tomography (CT) chest scan.
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A careful monitoring of the white blood count is obviously recommended.
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Blood analysis revealed an elevated erythrocyte sedimentation rate and polyclonal hypergammaglobulinemia.
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She was on etanercept and methotrexate for rheumatoid arthritis.
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He had been receiving dobutamine 3 mug/kg/min by intermittent i.v. infusion over four hours once weekly as an outpatient.
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A 57-year-old woman with end-stage kidney disease secondary to autosomal dominant polycystic kidney disease developed peritoneal dialysis-related Mucor peritonitis after her pet cockatoo bit through her transfer set.
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Cultures became negative 10-37 days after the introduction of the drug.
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Although, not included in the incidence calculation, four patients with CLL were referred at the time of development of AML/MDS.
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The authors report a case of Balint syndrome with irreversible posterior leukoencephalopathy on MRI following intrathecal methotrexate and cytarabine.
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The main possible diagnoses, especially in the elderly, are age-related macular degeneration, tamoxifen and cancer-associated retinopathy (CAR).
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First case of ivermectin-induced severe hepatitis.
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The reported cases of in utero exposure to cyclosposphamide shared the following manifestations with our patient: growth deficiency, developmental delay, craniosynostosis, blepharophimosis, flat nasal bridge, abnormal ears, and distal limb defects including hypoplastic thumbs and oligodactyly.
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Intravenous and subsequent long-term oral penicillin therapy was constituted and resulted in a significant decrease in the size of the pelvic mass.
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Several case reports of aplastic anemia with use of acetazolamide, and two cases with use of methazolamide, have appeared in the literature.
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Aspergillus cholangitis can occur in the portoenterostomy patient and may be highly resistant to conventional therapy.
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Asthmatic individuals are one of the higher risk groups suffering from dental erosion.
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We describe a 35-year-old woman who developed severe thrombotic complications due to heparinization and unrecognized HDAs.
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This confirmed the history of captopril-related asthma.
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Septicemia and septic shock are a leading cause of morbidity and mortality among hospitalized patients.
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Keratitis resolved within 8.4 weeks (range, 1-18 weeks) of treatment with fortified clarithromycin and amikacin.
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The entire bezoar could be removed endoscopically.
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Two months following LASIK, an epithelial dendritic lesion appeared in the lower third of the corneal flap of the left eye with vesiculoulcerative lesions of the lateral side of the tip of the nose.
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PURPOSE: We report a case of a patient who developed a postoperative anterior spinal artery syndrome that was masked by the use of epidural analgesia.
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After 5 days of treatment with IL-2, the patient developed a hemorrhagic lesion that progressed to toxic epidermal necrolysis, as well as grade 4 pancytopenia.
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A 64-year-old man presented with proteinuria during postoperative interferon (IFN)-beta therapy against malignant melanoma.
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Nocardia keratitis was diagnosed from her culture results, and the species Nocardia exalbida was determined by phylogenetic studies using gene sequence analysis of 16S RNA.
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