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Severe rhabdomyolysis following massive ingestion of oolong tea: caffeine intoxication with coexisting hyponatremia.
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Clofazimine enteropathy caused by crystal deposition can be life-threatening.
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The patient's previous rash and the temporal relation of this event and the ingestion of phenolphthalein, as well as the similarity of this case to other reports, point to phenolphthalein as the cause of TEN in this patient.
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The authors postulate that two types of combined lithium-neuroleptic toxicity occur: a neuroleptic malignant extrapyramidal syndrome and a lithium toxicity that occurs in combination with phenothiazines, primarily thioridazine.
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Glucocorticoids were administered at dosages that provided 1/3 to 1/2 of her expected maximal daily cortisol secretion during her complicated hospital course.
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BACKGROUND: Agenesis of the inferior vena cava (IVC) is an uncommon congenital vascular malformation.
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The literature is also reviewed for ARF associated with mannitol infusion in patients who received dialysis and those who did not receive dialysis; and the possible mechanism(s) of mannitol nephrotoxicity are discussed.
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Histiocytic lymphoma of the ileocecal region developed in a patient with multiple myeloma following successful long-term alkylating agent therapy.
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Because of his chronic diarrhea, this patient underwent colonoscopy, which revealed diffuse erythematous mucosa, multiple ulcers, exudate, and pseudopolyps with a diffuse loss of vascularity.
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PURPOSE: To report a case of Serratia Marcescens corneal ulcer as a complication of orthokeratology treatment.
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Laparoscopic surgery is inappropriate in patients with malignant ascites or when preoperative or intraoperative findings are suggestive of ovarian cancer.
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Four patients remained dialysis-dependent and died within 4 weeks of presentation.
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High signal intensity in periventricular white matter was observed on T2-weighted magnetic resonance imaging.
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Multicyclic dose-intensive chemotherapy supported by autologous blood progenitor cell transplantation for relapsed small cell lung cancer.
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Spontaneous intracerebral hemorrhage was diagnosed, despite an initial negative CT scan.
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By means of the in vitro heparin-induced platelet activation (HIPA) assay it was shown that standard heparin and the LMW heparins Fragmin and Fraxiparin (Sanofi Labaz, Munich, FRG), as well as the enoxaparine Clexane (Nattermann, Cologne, FRG), all induced platelet activation with the patient's serum.
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MAIN OUTCOME MEASURES: Visual acuity, color vision, Goldmann perimetry testing, and fundus photography.
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Recombinant human alpha-interferon (IFN) at a dose of 3 million units combined with melphalan and prednisolone was administrated.
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AIMS: The aim of this study was to report on the effectiveness and tumor side effects of topical interferon (INF) alpha 2-beta in a case of conjunctiva-cornea intraepithelial neoplasia (CIN) of a patient that rejected any surgical procedure.
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Five weeks later, the patient underwent arthroscopic evaluation of the shoulder and subacromial decompression.
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The occurrence of additional signs and symptoms should alert the clinician to the presence of intracranial pathology.
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A nerve conduction study showed conduction block at the elbow, indicating possible cubital tunnel syndrome.
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An immediate hemolytic reaction induced by repeated administration of oxaliplatin.
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Neuroleptic malignant syndrome in a burn patient.
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The first was a 56-year-old male treated with multiple chemotherapeutics for multiple myeloma.
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Radiation therapy is a powerful method for the control of cancer.
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Anaphylaxis to cisplatin following nine previous uncomplicated cycles.
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The reported case represents an unusual association between medication with the proton pump inhibitor lansoprazole and the development of collagenous colitis suggesting the importance of evaluation of drug use in patients with microscopic colitis.
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At delivery the umbilical cord plasma concentration was similar to that in the maternal venous plasma.
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Repeated open application tests with amcinonide and triamcinolone acetonide cream on the ventral aspect of the upper arm were negative.
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After reviewing the current literature, we suggest that there is no dose of methadone that may be considered to be completely safe.
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This is the first description, to our knowledge, of ductopenia apparently caused by clindamycin.
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The patient was treated with corticosteroid therapy and surgical resection of the jejunal tumor.
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In our experience, the correct diagnosis and effective treatment at an early stage proved to be helpful to the patients in pulling out from the critical stage of acute radiation sickness.
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Despite the extraordinary course in this patient, complete recovery took place, confirming the benign nature of even such a prolonged episode.
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The nocturia was defined as having more than two episodes of urination during sleep per night on average.
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Heart Vessels 2006;21:124?6].
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A 27-year-old man presented with corneal ectasia in his left eye 4 years after myopic laser in situ keratomileusis (LASIK) and was treated with riboflavin-ultraviolet-A (crosslinking).
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The patient underwent an elective termination of an intrauterine pregnancy and subsequently was diagnosed with a pulmonary embolus, which delayed the diagnosis of her ruptured ectopic pregnancy.
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Neurotoxicity occurs most often with intermittent high dose 5-FU as bolus injection or 24- to 48-h infusions.
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Methanol toxicity can cause severe central nervous system insult in which a characteristic pattern of bilateral putaminal injury is noted on brain imaging studies.
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Indications for GBP treatment were newly diagnosed epilepsy in one and painful paraesthesiae in the other.
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Up to now, all investigations have failed to show a relapse of her adenocarcinoma.
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Acute neutrophilic dermatosis induced by all-trans-retinoic acid treatment for acute promyelocytic leukemia.
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Reversible treatment-related leukoencephalopathy.
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Palliative radiation therapy was given.
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We report the case of a 20-year-old woman originally from Cameroon who was infected by the L. loa parasite and developed severe hepatitis, identified 1 month after a single dose of ivermectin.
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Multifocal osteonecrosis following chemotherapy and short-term corticosteroid therapy in a patient with small-cell bronchogenic carcinoma.
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CLINICAL FEATURES: A 61 yr old man with severe mitral regurgitation and chronic obstructive lung disease underwent surgery for mitral valve repair.
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All patients who died developed disseminated intravascular coagulation, and at postmortem examination were found to have had cerebral haemorrhage.
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Valacyclovir is an effective oral agent for the treatment of herpes virus infection, however, the pharmacokinetics of the drug are altered in renal failure.
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CONCLUSION: The hemolytic-uremic syndrome may be a rare complication of oxaliplatin-based chemotherapy.
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The introduction of para-aminosalicylic acid (PAS) led to hypoglycaemic coma.
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We report our conventional magnetic resonance and diffusion-weighted imaging findings and briefly discuss the pathophysiology of the syndrome.
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In one child, a second course of carbamazepine resulted in a return of the dystonia.
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The clinical manifestations, differential diagnosis, and treatment of the neuroleptic malignant syndrome and neuroleptic-induced catatonia are discussed.
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Bone formation induced in an infant by systemic prostaglandin-E2 administration.
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In all three cases, autopsy revealed gross and microscopic features indistinguishable from those seen in the Hamman-Rich syndrome, and methotrexate hepatotoxicity was present in one.
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The patient had recurrence of urticaria and angioedema a year and a half later, at which point the NPH was stopped and she was desensitized to regular insulin.
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She tolerated the surgery well and was discharged on postoperative day 5.
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Primary cutaneous coccidioidomycosis and subsequent drug eruption to itraconazole in a dog.
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CASE REPORT: We present a case of a 28-yr-old male who developed a severe case of nephrotic syndrome while being treated for relapsing/remitting Multiple Sclerosis (RRMS) with weekly injections of interferon beta 1a.
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However, the other antitubercular drugs were continued along with 40 mg of prednisolone in a single daily morning dose.
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Patients received CAP 1200-1600 mg/m2 in two divided doses with XRT (total 5040-5400 Gy) x 6 weeks, followed by 4 weeks rest, then 6 cycles of CAP 2000-2500 mg/m2 in two divided doses x 14 days every (q) 3 weeks.
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Progressive hypokalemia developed during phosphate treatment.
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Total blindness with a transient tonic pupillary response, denervation supersensitivity, and abnormal visual-evoked potentials developed in a 54-year-old man after the use of quinine sulfate for leg cramps.
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Some kindreds with familial parkinsonism exhibit genetic anticipation, suggesting possible involvement of trinucleotide repeat expansion.
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Non-lithium-induced renal failure with secondary lithium toxicity: case reports.
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These cases, combined with other reports in the literature, suggest strongly that these drugs are fetotoxic.
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Neutropenia is an infrequent complication following administration of the angiotensin-converting enzyme (ACE) inhibitor, captopril.
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In both cases, high fever, skin rash, liver dysfunction and atypical lymphocytosis developed 3 weeks after initiating treatment with SASP.
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Cervical and inguinal lymph node biopsies showed the features of severe necrotising lymphadenitis, associated with erythrophagocytosis and prominent eosinophilic infiltrates, without viral inclusion bodies, suggestive of an adverse drug reaction.A week later, fulminant drug-induced hepatitis, associated with the presence of anti-nuclear autoantibodies (but not with other markers of autoimmunity), and accompanied by multi-organ failure and sepsis, supervened.
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In case 1, a total daily dose of 25 mg sertraline, with nondetectable sertraline and desmethylsertraline blood levels, resulted in a doubling of the lamotrigine blood level with symptoms of toxicity.
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Adrenal suppression was discontinued, and she was reevaluated for hypercortisolism.
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The effects of aprotinin, a broad-based proteinase inhibitor, in the management of hemorrhagic complications during prolonged venovenous extracorporeal CO2 removal in patients with adult respiratory distress syndrome are not evaluated.
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The authors present an elderly patient with mixed dementia who developed TD at multiple sites, (including respiratory dyskinesia [RD], limb dyskinesia, and orofacial dyskinesia) following abrupt withdrawal of risperidone therapy.
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We report a case of shunt infection subsequent to insertion of a ventriculoatrial shunt for obstructive hydrocephalus caused by a cerebellar hematoma.
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Medical records and kidney biopsy specimens were reviewed and relevant data were collected.
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Meperidine-associated central nervous system (CNS) excitatory toxicities are believed to be caused by accumulation of the active metabolite normeperidine.
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Clomipramine was tapered and reduced to 50 mg over a period of 10 days.
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The most common associated cancers are ovarian, lung, pancreatic, stomach, colon and non-Hodgkin's lymphoma.
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This condition rapidly diminished after administration of intravenous antihistaminics and did not necessitate cessation of VRC treatment.
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Heavy proteinuria then developed and the drug was stopped.
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We believe these cases highlight important and potentially irreversible side effects of this agent and emphasize the need for further studies of the renal safety of TDF in pediatric patients.
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Trihexyphenidyl and isoprinosine in the treatment of subacute sclerosing panencephalitis.
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We report two patients with anhedonic ejaculation (ejaculation without orgasm) associated with initiation of treatment with desipramine.
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There was no evidence of recurrent myeloma after the initial remission on cyclophosphamide therapy.
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Development of hypertension in neuroblastoma during therapy: a case report.
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Tolazoline induces a dilatation of the pulmonary vascular system by stimulating H2 receptors.
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Inflammatory changes were observed in four out of nine patients on HAART and in one out of 19 patients not on HAART.
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Despite they can be distinguished through clinical and histological characteristics; both are often used as synonyms.
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All patients experienced an increase in hematocrit level.
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Pulmonary nodules caused by Schizophyllum commune after cardiac transplantation.
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Prolonged severe 5-fluorouracil-associated neurotoxicity in a patient with dihydropyrimidine dehydrogenase deficiency.
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A 47 year-old woman who had a 4-year history of intramuscular pentazocine injections in the lower extremities, developed gradual stiffness and weakness of the lower extremities.
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Initially, National Institutes of Health Stroke Scale score was 21, and 24 hours later it improved to 9.
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Hepatic artery aneurysm associated with upper gastrointestinal bleeding after intrahepatic artery chemotherapy.
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This case, although rare and atypical, should alert clinicians to consider the possibility of NMS as a complication of abrupt neuroleptic drug withdrawal.
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Physicians should be careful not to rule out the diagnosis in patients of high-risk ethnic backgrounds just because of atypical clinical features, as our data indicate that MEFV mutations are sometimes demonstrable in such patients.
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Transfusion-associated graft-versus-host disease (TA-GVHD), has rarely been reported associated with B-chronic lymphocytic leukaemia (B-CLL).
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