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We suggest discontinuing gemcitabine if radiation recall is observed.
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Thirty-three patients with primary ovarian malignancy were treated with cisplatin-based combination chemotherapy ranging from 1 to 12 (mean 4.6) cycles.
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To date, there have been few reports of visual disturbances associated with BTX-B use.
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Histological examination of the liver revealed inflammatory reactions, cholestasis, occasional steatosis, and necrosis.
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CONCLUSION: TLS is an uncommon, but potentially life-threatening, complication in melanoma and other solid tumors.
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The role of anticoagulation with heparin is controversial in the absence of any controlled studies.
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This report describes a probable case of infliximab-induced membranous nephropathy.
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We report a 5-year-old boy with CF who had a stricture of the hepatic flexure region with associated narrowing due to submucosal fibrosis of the transverse colon, secondary to high-lipase pancreatin therapy.
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Microangiopathic hemolytic anemia (MAHA) is a late but fatal complication in advanced cancers (cancer-associated).
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CONCLUSION: Hypersensitivity reaction should be considered in patients who develop recurrent eosinophilia and deterioration of pulmonary function following the use of tobramycin by inhalation or by intravenous administration.
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The microbiology culture was negative.
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Laboratory tests revealed creatine kinase (CK) 7952 IU/L, lactate dehydrogenase 1021 IU/L, myoglobin 2322 U/L, and aspartate aminotransferase 362 IU/L, resulting in a diagnosis of iatrogenic rhabdomyolysis.
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Some much-quoted early studies noted abnormalities in liver function tests (LFTs) in very obese patients taking high doses, although there was no evidence of clinically significant liver dysfunction.
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Medical consultation is imperative for these patients before administering a fluid challenge during general anesthesia.
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Fever, pulmonary infiltrates, and pleural effusion following acyclovir therapy for herpes zoster ophthalmicus.
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Metabolic acidosis induced by acetazolamide.
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Motor neuropathy, anemia and all gastrointestinal symptoms disappeared.
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Tricyclic antidepressant toxicity treated with massive sodium bicarbonate.
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SUMMARY: Unfortunately, the clinical features of the oral adverse effect from NVP are not well known.
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Histopathological findings included signs of orthokeratotic hyperkeratosis, moderate follicular keratosis and light epidermic acanthosis.
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Serum creatinine remained above pre-treatment values in seven patients.
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We report a patient who developed early onset PCP after allogeneic peripheral blood stem cell transplantation (PBSCT) from an HLA-identical sibling donor.
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We describe a patient with systemic lupus erythematosus and impaired renal function probably mainly due to tubulointerstitial disease.
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Right atrial thrombus and recurrent pulmonary emboli secondary to permanent cardiac pacing--a case report and short review of literature.
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The patient did well after the operation and returned to normal activity.
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Additionally, a baby bottle allegedly administered to the infant was collected as evidence and sent to the Medical Examiner's Office for evaluation.
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Asthenozoospermia: possible association with long-term exposure to an anti-epileptic drug of carbamazepine.
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We report on a case of an adult patient treated for rheumatoid arthritis with infliximab, a chimerical monoclonal antibody to TNFalpha.
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Anasarca eventually subsided within 4 weeks with the use of a diuretic agent.
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Single and multiple verrucous plantaris lesions are well known for their resistance to conservative methods of treatment.
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He developed a painful symmetrical purpuric eruption over both feet after three days.
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Patient 2 is a 53-year-old man who underwent fibular osteocutaneous free-flap reconstruction of a floor of mouth defect who developed venous thrombosis 6 days postoperatively.
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Clear guidelines and access to support are often lacking.
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Platelet count less than SHARP: what does a case series reveal?
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Anaphylactic reaction to bacitracin ointment.
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An abdominal radiograph revealed gross fecal loading.
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Consequently, intravenous salmon calcitonin was administered, based on evidence of efficacy in the treatment of other neuropathic pain syndromes and its relatively benign side-effects profile.
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OBJECTIVE: To describe a case of sertraline-induced rhabdomyolysis in an elderly patient with dementia and comorbidities.
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The paper outlines the correct treatment and discusses the deleterious effects of incorrect administration of drugs in WPW syndrome.
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There are many challenges associated with treating invasive aspergillosis, particularly that due to A. terreus, and the early use of caspofungin should be considered.
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A 29-year-old woman who underwent laser in situ keratomileusis (LASIK) for myopic astigmatism in both eyes presented with severe pain, photophobia and decreased visual acuity in the left eye eight days after surgery.
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Myoclonus was induced and enhanced by L-dopa, developing into generalized seizures.
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All patients showed marked improvement clinically, endoscopically, and histologically.
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DISCUSSION: Anaphylactoid reactions have been described previously with cisplatin administration.
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Symptomatic hypoglycemia secondary to a glipizide-trimethoprim/sulfamethoxazole drug interaction.
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Four cases of oesophageal damage associated with ingestion of the urinary anti-spasmodic agent emepronium bromide are described.
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Photo-onycholysis caused by olanzapine and aripiprazole.
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The authors report a case of a 12-year-old girl who had rare self induced photosensitive epilepsy.
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It is likely that RA contributed to the deterioration in renal function in these patients.
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The cessation of angiographic leakage on FA was achieved in all eyes (100%) after IVB, however the hypofluorescent line delineating the margin of the neovascular tissue appeared in ICGA seemingly according to the contraction of mCNV.
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Systemic lupus erythematosus and IPH were diagnosed 6 years later.
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The results of the comparative study led us to the conclusion that the compression technique is a simple and valuable means of decreasing the side-effects of Adriamycin and increasing tumor response.
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In the second case, mild atypical change by presence of nuclear enlargement and rare mitotic figures were noted and PCNA, KI67 levels were less than 2%.
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INVESTIGATIONS: Physical examination, blood and urine analyses, kidney biopsy and tonicity balance.
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We assumed this to be related to the advancing central nervous system aspergillosis.
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Although tandem scanning confocal microscopy of Acanthamoeba has been described in previous reports, Acanthamoeba keratitis has not been fully characterized with this instrument.
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OBJECTIVE: To report the late development of immune-mediated diabetes mellitus after completion of alfa-interferon therapy for hepatitis C in an Asian patient.
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Blood transfusion and natural infection cases.
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Bland emollients and reduction in the dose of PLD resulted in resolution of the eruption.
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Morbidity included extended hospitalization, dialysis, and chronic renal failure.
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The neurotoxicity seen with HDARAC is dose-related and has occurred in up to 60 percent of treated patients.
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Serum lithium levels fell rapidly, but the cognitive impairment associated with the delirium typically persisted for another week or two.
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Warfarin-associated bleeding complication saved life.
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Exacerbation of schizophrenia associated with amantadine.
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Myasthenia-like syndrome induced by cardiovascular agents.
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Postoperatively, a continuous epidural infusion of fentanyl/bupivacaine was used for postoperative pain management.
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Six cases of subacute sclerosing panencephalitis (1 stage I, 3 stage II, 2 stage III) were diagnosed at our institution in the last 10 years.
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Cimetidine is a rare cause of drug-induced fever.
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Initially, DSCG had helped to control his asthmatic attacks, and steroid therapy could be discontinued.
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Case presentation, management, and etiology are discussed.
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She developed a severe urticarial rash 3 weeks following initiation of therapy with Enoxaparin.
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Treatment with infliximab is known to produce an increase of autoantibodies (antinuclear antibodies, anti-double-stranded DNA), but not clinical disease.
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Esophageal spasm following propranolol overdose relieved by glucagon.
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Acute occlusion of the popliteal artery, a limb-threatening complication, was reported after total knee arthroplasty.
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Steroid utilization in eosinophilic jejunitis: beneficial or harmful?
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Probable propafenone-induced transient global amnesia.
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Clonally rearranged immunoglobulin heavy chain JH gene was not detected by Southern blot analysis.
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The more common grade 3 or 4 adverse effects of sunitinib include hypertension, fatigue, hand-foot syndrome, elevated lipase and lymphopenia.
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Personality factors and drug effects in a controlled study of cyclazocine.
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No patient died of INFVA.
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An additional 15 asymptomatic patients who were receiving high doses of oral niacin (1.0-6.0 g daily) for the treatment of hypercholesterolemia were evaluated for evidence of subclinical macular disease.
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We present a case of chronic postoperative Propionibacterium acnes endophthalmitis in which the diagnosis was made by anterior chamber paracentesis, and topical, periocular, and systemic antibiotic therapy resolved the inflammation.
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No other common disease known to affect mitral valves nor intake of other drugs (ergot derivatives or appetite suppressant drugs) was found.
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Our experience with donepezil in this group of patients shows promise.
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Skin biopsy specimens of lesional areas showed a bullous eruption consistent with erythema multiforme.
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The 38-year-old patient with no previous cardiac or smoking history developed complete heart block, ventricular fibrillation and subsequent asystole.
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Edema is an adverse event associated with thiazolidinedione therapy The potential for mild-to-moderate peripheral edema with thiazolidinedione is known, especially in patients who have heart failure or use insulin.
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A patient with coccidioidal meningitis was treated with intrathecally administered amphotericin B, and an acute toxic delirium with EEG abnormalities developed.
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We report an additional case of isotretinoin teratogenicity in which the patient had agenesis of the cerebellar vermis, multiple leptomeningeal neuroglial heterotopias, hydrocephalus, and abnormalities of the corticospinal tracts.
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The present authors report the case of an adult with chronic granulomatous disease who developed an unusual lung fibrosis associated with severe pulmonary hypertension.
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DPD activity was normal in both patients.
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Postoperative pyoderma gangrenosum (PPG), also known as postoperative progressive gangrene of Cullen, is a rare and rapidly evolving complication of surgical procedures.
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Although, a systemic steroid taper was employed in 10 out of the 14 patients before the development of the skin lesions, the subsequent progression of the skin lesions was not influenced by the use of systemic steroid therapy.
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The authors present a case report of a granulomatous reaction leading to urethral prolapse, 3 months after the transurethral injection of calcium hydroxylapatite.
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The alveolar form of hydatid disease, caused by the larval stage of the cestode Echinococcus multilocularis, is virtually confined geographically to the northern hemisphere.
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These symptoms were transient and fully reversible.
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Both patients developed massive subchorionic hematomas, which persisted in 1 patient who underwent cesarean delivery at 34 weeks of gestation for cardiac indications (Apgar scores 9 and 10 at 1 minute and 5 minutes, respectively).
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It was postulated that the allergic reaction was most likely caused by capecitabine or the intermediate metabolites based on the immediate reappearance of symptoms from the rechallenge, pharmacokinetic data, and well-tolerance of fluorouracil.
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CONCLUSION: During and after IFN therapy, OCT is a useful examination technique for revealing macular edema in patients who have decreased vision.
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We found TPO and platelet responses to be generally antagonistic through all cycles.
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