popV/tabula_muris_All_Smart-seq2

Popular Vote (popV) model for automated cell type annotation of single-cell RNA-seq data. We provide here pretrained models for plug-in use in your own analysis. Follow our tutorial to learn how to use the model for cell type annotation.

Model description

Ageing is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. Despite rapid advances over recent years, many of the molecular and cellular processes that underlie the progressive loss of healthy physiology are poorly understood. To gain a better insight into these processes, here we generate a single-cell transcriptomic atlas across the lifespan of Mus musculus that includes data from 23 tissues and organs. We found cell-specific changes occurring across multiple cell types and organs, as well as age-related changes in the cellular composition of different organs. Using single-cell transcriptomic data, we assessed cell-type-specific manifestations of different hallmarks of ageing—such as senescence, genomic instability and changes in the immune system. This transcriptomic atlas—which we denote Tabula Muris Senis, or ‘Mouse Ageing Cell Atlas’—provides molecular information about how the most important hallmarks of ageing are reflected in a broad range of tissues and cell types.

Link to CELLxGENE: Link to the data in the CELLxGENE browser for interactive exploration of the data and download of the source data.

Training Code URL: Not provided by uploader.

Metrics

We provide here accuracies for each of the experts and the ensemble model. The validation set accuracies are computed on a 10% random subset of the data that was not used for training.

Cell Type	N cells	celltypist	knn bbknn	knn harmony	knn on scvi	onclass	scanvi	svm	xgboost	Consensus Prediction
microglial cell	1336	0.99	0.99	0.96	0.99	0.00	0.96	0.99	0.99	0.99
B cell	555	0.65	0.71	0.72	0.68	0.00	0.71	0.65	0.70	0.77
endothelial cell	482	0.79	0.84	0.80	0.70	0.00	0.70	0.86	0.82	0.89
mesenchymal stem cell of adipose tissue	455	0.84	0.89	0.75	0.65	0.00	0.65	0.93	0.86	0.90
basal cell of epidermis	406	0.87	0.91	0.84	0.86	0.00	0.81	0.93	0.89	0.93
fibroblast of cardiac tissue	342	0.93	0.93	0.73	0.63	0.00	0.19	0.97	0.93	0.95
hematopoietic stem cell	312	0.95	0.95	0.94	0.95	0.00	0.94	0.98	0.96	0.97
granulocyte	294	0.89	0.91	0.89	0.86	0.00	0.71	0.92	0.91	0.93
naive B cell	334	0.46	0.09	0.54	0.41	0.00	0.19	0.58	0.65	0.41
skeletal muscle satellite cell	278	0.98	0.98	0.95	0.95	0.00	0.95	0.97	0.96	0.98
endothelial cell of coronary artery	263	0.78	0.81	0.63	0.43	0.00	0.64	0.89	0.83	0.90
keratinocyte stem cell	255	0.93	0.93	0.95	0.93	0.00	0.93	0.97	0.94	0.96
myeloid cell	240	0.51	0.67	0.51	0.46	0.00	0.53	0.68	0.67	0.69
enterocyte of epithelium of large intestine	269	0.91	0.93	0.88	0.94	0.00	0.94	0.94	0.91	0.94
macrophage	251	0.35	0.52	0.44	0.46	0.00	0.34	0.51	0.55	0.59
basal cell	206	1.00	0.99	0.97	0.94	0.00	0.95	0.99	0.98	0.99
bronchial smooth muscle cell	208	0.95	0.95	0.85	0.71	0.00	0.89	0.95	0.96	0.96
oligodendrocyte	221	0.99	1.00	0.99	1.00	0.00	0.99	1.00	0.99	1.00
DN4 thymocyte	166	0.61	0.62	0.42	0.53	0.00	0.52	0.77	0.75	0.75
epithelial cell of large intestine	172	0.89	0.88	0.72	0.83	0.00	0.86	0.93	0.91	0.91
thymocyte	150	0.89	0.91	0.74	0.83	0.00	0.84	0.91	0.92	0.92
large intestine goblet cell	168	0.80	0.85	0.81	0.82	0.00	0.81	0.91	0.89	0.90
intestinal crypt stem cell	155	0.86	0.90	0.81	0.87	0.00	0.89	0.94	0.89	0.93
mesenchymal stem cell	176	0.70	0.80	0.59	0.47	0.00	0.53	0.89	0.81	0.86
bladder urothelial cell	124	0.97	0.96	0.92	0.90	0.00	0.93	0.99	0.99	0.98
type B pancreatic cell	129	0.99	0.98	0.93	0.97	0.00	0.98	0.99	0.98	0.99
fibroblast	136	0.51	0.65	0.31	0.37	0.00	0.34	0.87	0.71	0.74
T cell	101	0.33	0.39	0.38	0.30	0.00	0.37	0.44	0.47	0.45
monocyte	115	0.55	0.72	0.52	0.57	0.00	0.46	0.77	0.75	0.80
keratinocyte	130	0.81	0.90	0.71	0.74	0.00	0.78	0.94	0.87	0.93
CD4-positive, alpha-beta T cell	142	0.57	0.64	0.49	0.45	0.00	0.55	0.58	0.63	0.70
hepatocyte	102	0.96	0.96	0.97	0.94	0.00	0.95	0.97	0.95	0.97
CD8-positive, alpha-beta T cell	111	0.52	0.47	0.48	0.46	0.00	0.54	0.51	0.58	0.59
promonocyte	98	0.48	0.69	0.61	0.46	0.00	0.53	0.72	0.73	0.76
bladder cell	88	0.99	0.99	0.90	0.64	0.00	0.81	1.00	0.96	0.99
natural killer cell	96	0.78	0.76	0.70	0.60	0.00	0.71	0.71	0.72	0.79
precursor B cell	86	0.84	0.87	0.68	0.73	0.00	0.84	0.89	0.88	0.90
luminal epithelial cell of mammary gland	80	0.92	0.95	0.94	0.91	0.00	0.90	0.97	0.96	0.96
endothelial cell of hepatic sinusoid	59	0.93	0.97	0.90	0.81	0.00	0.88	0.93	0.93	0.94
astrocyte	53	0.85	0.94	0.88	0.92	0.00	0.95	0.94	0.93	0.95
immature B cell	48	0.63	0.52	0.39	0.27	0.00	0.46	0.60	0.56	0.71
pancreatic acinar cell	58	0.97	0.97	0.97	0.95	0.00	0.98	1.00	1.00	1.00
secretory cell	61	0.68	0.56	0.42	0.45	0.00	0.67	0.86	0.84	0.80
pancreatic A cell	67	0.88	0.92	0.86	0.90	0.00	0.94	0.96	0.95	0.94
epidermal cell	59	0.82	0.79	0.39	0.69	0.00	0.69	0.84	0.76	0.83
neuron	37	0.65	0.68	0.60	0.68	0.00	0.85	0.92	0.82	0.86
brain pericyte	40	0.79	0.83	0.73	0.74	0.00	0.91	0.95	0.88	0.86
granulocytopoietic cell	46	0.75	0.86	0.76	0.85	0.00	0.78	0.86	0.80	0.83
fibroblast of lung	48	0.95	0.95	0.93	0.92	0.00	0.93	0.97	0.95	0.97
kidney collecting duct epithelial cell	33	0.61	0.86	0.85	0.79	0.00	0.98	0.99	0.99	0.98
aortic endothelial cell	9	0.00	0.00	0.00	0.00	0.00	0.14	0.11	0.08	0.09
epithelial cell	34	0.31	0.11	0.43	0.41	0.00	0.37	0.54	0.48	0.59
late pro-B cell	38	0.88	0.94	0.93	0.84	0.00	0.91	0.96	0.92	0.97
basal epithelial cell of tracheobronchial tree	34	0.62	0.51	0.42	0.61	0.00	0.67	0.89	0.80	0.88
regular atrial cardiac myocyte	39	0.45	0.64	0.73	0.61	0.00	0.58	0.76	0.77	0.80
epithelial cell of proximal tubule	33	0.35	0.78	0.69	0.71	0.00	0.91	0.96	0.97	0.93
endocardial cell	38	0.96	0.95	0.93	0.80	0.00	0.82	0.97	0.96	0.99
myeloid dendritic cell	39	0.48	0.57	0.12	0.33	0.00	0.44	0.75	0.70	0.68
stromal cell	25	0.26	0.35	0.20	0.29	0.00	0.36	0.58	0.58	0.62
mature alpha-beta T cell	32	0.22	0.15	0.09	0.31	0.00	0.36	0.36	0.49	0.26
cardiac valve cell	33	0.78	0.85	0.78	0.81	0.00	0.88	0.90	0.86	0.85
pancreatic ductal cell	34	1.00	0.99	0.99	0.96	0.00	0.99	1.00	1.00	1.00
oligodendrocyte precursor cell	36	0.97	0.99	0.93	0.93	0.00	1.00	0.99	0.94	0.99
adventitial cell	41	0.48	0.40	0.31	0.10	0.00	0.27	0.79	0.55	0.69
chondrocyte	23	0.73	0.79	0.81	0.67	0.00	0.81	0.89	0.85	0.83
Kupffer cell	38	0.99	0.93	0.84	0.85	0.00	0.80	0.97	0.92	0.97
granulocyte monocyte progenitor cell	21	0.65	0.78	0.81	0.68	0.00	0.79	0.84	0.86	0.88
interneuron	25	0.49	0.67	0.47	0.60	0.00	0.89	0.96	0.89	0.88
myeloid leukocyte	17	0.00	0.21	0.38	0.29	0.00	0.06	0.20	0.50	0.20
classical monocyte	13	0.00	0.27	0.28	0.22	0.00	0.36	0.62	0.57	0.53
mature NK T cell	19	0.40	0.17	0.26	0.16	0.00	0.46	0.33	0.68	0.58
pancreatic D cell	17	0.94	0.90	0.82	0.94	0.00	0.92	1.00	1.00	1.00
brush cell of epithelium proper of large intestine	15	0.76	0.73	0.33	0.74	0.00	0.64	0.94	0.88	0.90
epithelial cell of thymus	19	0.10	0.00	0.18	0.55	0.00	0.46	0.56	0.49	0.53
enteroendocrine cell	11	0.95	0.62	0.53	0.86	0.00	0.81	0.90	1.00	0.95
leukocyte	16	0.00	0.61	0.40	0.00	0.00	0.06	0.75	0.81	0.67
neutrophil	12	0.00	0.00	0.00	0.00	0.00	0.18	0.42	0.40	0.11
vein endothelial cell	13	0.43	0.27	0.20	0.12	0.00	0.78	1.00	0.74	0.70
kidney collecting duct principal cell	11	0.00	0.86	0.73	0.78	0.00	0.87	0.91	0.83	0.95
neuroepithelial stem cell	22	0.32	0.09	0.43	0.50	0.00	0.62	0.83	0.74	0.84
non-classical monocyte	16	0.00	0.55	0.33	0.22	0.00	0.46	0.67	0.72	0.59
regular ventricular cardiac myocyte	16	0.43	0.00	0.81	0.80	0.00	0.82	1.00	0.94	0.86
kidney loop of Henle ascending limb epithelial cell	12	0.63	0.85	0.77	0.80	0.00	0.96	0.96	0.87	0.92
smooth muscle cell of trachea	11	0.00	0.00	0.21	0.27	0.00	0.29	0.52	0.46	0.40
professional antigen presenting cell	2	0.00	0.00	0.14	0.50	0.00	0.33	0.36	0.21	0.50
smooth muscle cell of the pulmonary artery	6	0.00	0.44	0.00	0.33	0.00	0.27	0.83	0.77	0.91
proerythroblast	10	0.00	0.40	0.24	0.31	0.00	0.17	0.30	0.40	0.12
smooth muscle cell	14	0.00	0.58	0.33	0.24	0.00	0.67	0.93	0.84	0.77
medium spiny neuron	11	1.00	0.95	0.40	0.86	0.00	0.96	1.00	1.00	1.00
endothelial cell of lymphatic vessel	7	0.47	0.46	0.83	0.22	0.00	0.52	0.88	0.64	0.82
neural stem cell	14	0.00	0.80	0.72	0.64	0.00	0.79	0.89	0.75	0.85
mesangial cell	8	0.00	0.40	0.00	0.00	0.00	0.21	0.43	0.56	0.55
megakaryocyte-erythroid progenitor cell	10	0.32	0.40	0.40	0.57	0.00	0.55	0.57	0.67	0.64
mucus secreting cell	9	0.64	0.55	0.71	0.62	0.00	0.89	0.95	1.00	0.90
early pro-B cell	7	0.00	0.83	0.83	0.86	0.00	0.86	0.86	0.80	0.92
pancreatic PP cell	8	0.00	0.40	0.22	0.20	0.00	0.71	0.88	0.80	0.40
basophil	11	0.27	0.43	0.84	0.64	0.00	0.69	0.95	0.82	0.87
ciliated columnar cell of tracheobronchial tree	9	0.62	0.84	0.88	0.82	0.00	0.82	0.90	0.82	0.95
dendritic cell	8	0.44	0.29	0.00	0.42	0.00	0.31	0.59	0.47	0.42
ependymal cell	6	0.00	0.60	0.67	0.92	0.00	0.80	1.00	0.92	1.00
Bergmann glial cell	2	0.00	0.67	0.67	0.50	0.00	0.50	0.50	0.50	0.67
pulmonary interstitial fibroblast	4	0.38	0.50	0.50	0.75	0.00	0.67	0.86	0.67	0.67
pancreatic stellate cell	3	0.67	0.67	0.67	0.00	0.00	0.18	0.67	0.57	0.67
regulatory T cell	4	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
pericyte	4	0.00	0.67	0.75	0.67	0.00	0.67	0.75	0.89	0.75
fibrocyte	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
respiratory basal cell	6	0.00	0.00	0.00	0.67	0.00	0.56	0.80	0.91	0.67
plasma cell	2	0.17	0.00	0.00	0.00	0.00	0.22	0.00	0.36	0.36
club cell	2	0.00	0.00	0.10	0.20	0.00	0.11	0.67	0.29	0.40
kidney interstitial fibroblast	1	0.00	0.00	0.00	0.00	0.00	0.00	0.00	1.00	0.00
lymphoid lineage restricted progenitor cell	2	0.00	0.00	0.67	1.00	0.00	0.80	0.67	0.67	0.67
intermediate monocyte	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
lymphocyte	1	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
lung macrophage	1	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
plasmacytoid dendritic cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
lung neuroendocrine cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00

The train accuracies are computed on the training data.

Cell Type	N cells	celltypist	knn bbknn	knn harmony	knn on scvi	onclass	scanvi	svm	xgboost	Consensus Prediction
microglial cell	11932	0.99	0.99	0.95	0.99	0.00	0.97	0.99	0.99	1.00
B cell	5056	0.64	0.71	0.82	0.78	0.00	0.93	0.69	0.73	0.86
endothelial cell	4433	0.79	0.79	0.85	0.78	0.00	0.81	0.87	0.84	0.92
mesenchymal stem cell of adipose tissue	4275	0.85	0.88	0.81	0.76	0.00	0.97	0.94	0.88	0.96
basal cell of epidermis	3808	0.84	0.89	0.92	0.90	0.00	0.81	0.93	0.91	0.93
fibroblast of cardiac tissue	3575	0.92	0.91	0.81	0.78	0.00	0.96	0.95	0.92	0.96
hematopoietic stem cell	2994	0.93	0.94	0.96	0.96	0.00	0.96	0.97	0.96	0.97
granulocyte	2672	0.89	0.91	0.90	0.92	0.00	0.94	0.95	0.94	0.96
naive B cell	2625	0.38	0.02	0.75	0.61	0.00	0.92	0.61	0.66	0.73
skeletal muscle satellite cell	2441	0.97	0.97	0.91	0.98	0.00	0.97	0.98	0.97	0.98
endothelial cell of coronary artery	2431	0.76	0.75	0.81	0.63	0.00	0.87	0.91	0.87	0.95
keratinocyte stem cell	2384	0.94	0.94	0.96	0.95	0.00	0.95	0.97	0.95	0.97
myeloid cell	2307	0.52	0.66	0.70	0.66	0.00	0.82	0.77	0.78	0.85
enterocyte of epithelium of large intestine	2273	0.91	0.94	0.95	0.95	0.00	0.94	0.95	0.94	0.96
macrophage	2192	0.33	0.48	0.72	0.63	0.00	0.67	0.60	0.66	0.72
basal cell	1933	0.99	0.98	0.98	0.96	0.00	0.97	0.99	0.99	0.99
bronchial smooth muscle cell	1907	0.94	0.93	0.81	0.77	0.00	0.94	0.98	0.96	0.97
oligodendrocyte	1873	0.98	0.99	0.98	1.00	0.00	0.99	1.00	0.99	0.99
DN4 thymocyte	1590	0.59	0.56	0.66	0.69	0.00	0.92	0.86	0.86	0.88
epithelial cell of large intestine	1532	0.88	0.88	0.87	0.88	0.00	0.89	0.95	0.93	0.94
thymocyte	1475	0.88	0.90	0.80	0.92	0.00	0.93	0.95	0.96	0.95
large intestine goblet cell	1419	0.78	0.83	0.89	0.88	0.00	0.92	0.96	0.93	0.95
intestinal crypt stem cell	1424	0.87	0.90	0.91	0.91	0.00	0.90	0.95	0.91	0.95
mesenchymal stem cell	1250	0.64	0.68	0.65	0.60	0.00	0.92	0.89	0.84	0.91
bladder urothelial cell	1278	0.98	0.94	0.95	0.94	0.00	0.98	0.99	0.99	0.99
type B pancreatic cell	1213	0.96	0.96	0.90	0.96	0.00	0.97	0.98	0.98	0.97
fibroblast	1193	0.48	0.54	0.60	0.54	0.00	0.96	0.92	0.83	0.92
T cell	1218	0.49	0.52	0.60	0.59	0.00	0.71	0.74	0.77	0.74
monocyte	1165	0.60	0.72	0.83	0.73	0.00	0.82	0.86	0.84	0.91
keratinocyte	1084	0.76	0.88	0.91	0.83	0.00	0.78	0.93	0.90	0.92
CD4-positive, alpha-beta T cell	1028	0.54	0.54	0.66	0.60	0.00	0.72	0.73	0.79	0.78
hepatocyte	1047	0.96	0.95	0.95	0.96	0.00	0.96	0.98	0.98	0.98
CD8-positive, alpha-beta T cell	959	0.49	0.51	0.62	0.59	0.00	0.74	0.75	0.78	0.76
promonocyte	917	0.45	0.60	0.93	0.61	0.00	0.95	0.87	0.87	0.95
bladder cell	914	0.98	0.98	0.91	0.80	0.00	0.99	1.00	0.96	1.00
natural killer cell	779	0.75	0.75	0.75	0.73	0.00	0.80	0.88	0.90	0.88
precursor B cell	770	0.83	0.85	0.87	0.80	0.00	0.90	0.96	0.95	0.94
luminal epithelial cell of mammary gland	688	0.95	0.96	0.99	0.97	0.00	0.95	1.00	0.98	0.99
endothelial cell of hepatic sinusoid	558	0.94	0.85	0.90	0.84	0.00	0.92	0.99	0.98	0.99
astrocyte	539	0.86	0.93	0.95	0.95	0.00	0.97	0.99	0.99	0.98
immature B cell	541	0.64	0.55	0.63	0.54	0.00	0.80	0.79	0.79	0.87
pancreatic acinar cell	518	0.92	0.94	0.94	0.94	0.00	0.97	0.99	0.99	0.98
secretory cell	502	0.64	0.28	0.78	0.71	0.00	0.86	0.95	0.91	0.93
pancreatic A cell	454	0.83	0.82	0.87	0.87	0.00	0.92	0.97	0.96	0.91
epidermal cell	433	0.72	0.67	0.78	0.77	0.00	0.65	0.84	0.82	0.83
neuron	447	0.69	0.66	0.72	0.80	0.00	0.91	0.98	0.97	0.95
brain pericyte	444	0.79	0.80	0.82	0.83	0.00	0.94	1.00	0.98	0.92
granulocytopoietic cell	437	0.78	0.87	0.90	0.89	0.00	0.81	0.93	0.92	0.94
fibroblast of lung	431	0.96	0.96	0.88	0.88	0.00	0.98	0.99	0.97	0.99
kidney collecting duct epithelial cell	407	0.65	0.81	0.88	0.81	0.00	0.96	1.00	0.99	0.97
aortic endothelial cell	420	0.21	0.02	0.39	0.40	0.00	0.67	0.55	0.49	0.82
epithelial cell	392	0.30	0.04	0.72	0.64	0.00	0.76	0.72	0.74	0.82
late pro-B cell	373	0.84	0.91	0.93	0.86	0.00	0.94	0.99	0.98	0.97
basal epithelial cell of tracheobronchial tree	367	0.69	0.53	0.80	0.69	0.00	0.88	0.95	0.88	0.94
regular atrial cardiac myocyte	360	0.54	0.60	0.81	0.72	0.00	0.74	0.81	0.88	0.91
epithelial cell of proximal tubule	349	0.39	0.77	0.87	0.77	0.00	0.95	0.99	0.99	0.96
endocardial cell	337	0.96	0.93	0.96	0.83	0.00	0.93	0.96	0.95	0.97
myeloid dendritic cell	334	0.45	0.47	0.86	0.58	0.00	0.91	0.89	0.82	0.88
stromal cell	315	0.24	0.19	0.62	0.47	0.00	0.94	0.76	0.68	0.92
mature alpha-beta T cell	298	0.32	0.19	0.60	0.48	0.00	0.80	0.74	0.86	0.83
cardiac valve cell	282	0.86	0.91	0.81	0.88	0.00	0.95	0.96	0.97	0.94
pancreatic ductal cell	279	0.98	0.97	0.99	0.94	0.00	0.98	0.99	0.99	0.99
oligodendrocyte precursor cell	276	0.96	0.98	0.95	0.98	0.00	0.99	1.00	1.00	1.00
adventitial cell	247	0.48	0.52	0.72	0.30	0.00	0.89	0.89	0.73	0.95
chondrocyte	252	0.87	0.80	0.91	0.82	0.00	0.89	0.98	0.95	0.95
Kupffer cell	224	0.94	0.64	0.88	0.82	0.00	0.75	0.98	0.97	0.99
granulocyte monocyte progenitor cell	229	0.62	0.78	0.87	0.86	0.00	0.83	0.90	0.89	0.91
interneuron	215	0.55	0.68	0.82	0.76	0.00	0.89	0.98	0.94	0.90
myeloid leukocyte	192	0.00	0.11	0.82	0.40	0.00	0.87	0.91	0.89	0.97
classical monocyte	189	0.00	0.34	0.64	0.53	0.00	0.90	0.87	0.86	0.92
mature NK T cell	180	0.35	0.14	0.66	0.38	0.00	0.72	0.91	0.92	0.91
pancreatic D cell	174	0.90	0.89	0.87	0.89	0.00	0.91	0.99	0.98	0.96
brush cell of epithelium proper of large intestine	160	0.76	0.76	0.77	0.81	0.00	0.85	0.98	0.97	0.94
epithelial cell of thymus	146	0.22	0.01	0.58	0.50	0.00	0.76	0.89	0.78	0.93
enteroendocrine cell	150	0.88	0.53	0.76	0.89	0.00	0.91	0.99	0.98	0.98
leukocyte	142	0.00	0.31	0.71	0.44	0.00	0.74	0.81	0.85	0.95
neutrophil	141	0.00	0.10	0.28	0.21	0.00	0.80	0.75	0.69	0.80
vein endothelial cell	139	0.53	0.54	0.71	0.30	0.00	0.88	0.95	0.89	0.85
kidney collecting duct principal cell	140	0.00	0.78	0.88	0.75	0.00	0.96	0.99	0.96	0.98
neuroepithelial stem cell	129	0.21	0.03	0.84	0.73	0.00	0.73	0.91	0.83	0.93
non-classical monocyte	133	0.00	0.36	0.59	0.38	0.00	0.83	0.81	0.77	0.89
regular ventricular cardiac myocyte	129	0.53	0.00	0.87	0.84	0.00	0.91	0.98	0.98	0.98
kidney loop of Henle ascending limb epithelial cell	132	0.65	0.85	0.92	0.69	0.00	0.96	1.00	0.99	0.99
smooth muscle cell of trachea	114	0.00	0.11	0.58	0.52	0.00	0.85	0.85	0.77	0.84
professional antigen presenting cell	114	0.14	0.15	0.53	0.61	0.00	0.84	0.87	0.80	0.93
smooth muscle cell of the pulmonary artery	105	0.00	0.55	0.77	0.40	0.00	0.53	0.89	0.83	0.91
proerythroblast	97	0.00	0.10	0.62	0.28	0.00	0.76	0.92	0.87	0.89
smooth muscle cell	89	0.00	0.34	0.67	0.42	0.00	0.95	0.97	0.92	0.91
medium spiny neuron	92	0.98	0.54	0.83	0.88	0.00	0.94	1.00	0.99	0.99
endothelial cell of lymphatic vessel	92	0.47	0.41	0.93	0.55	0.00	0.63	0.81	0.72	0.85
neural stem cell	83	0.00	0.75	0.83	0.94	0.00	0.93	1.00	0.95	0.99
mesangial cell	84	0.00	0.16	0.61	0.39	0.00	0.79	0.86	0.68	0.91
megakaryocyte-erythroid progenitor cell	70	0.30	0.27	0.80	0.82	0.00	0.81	0.89	0.96	0.94
mucus secreting cell	64	0.57	0.64	0.86	0.82	0.00	0.96	0.95	0.98	0.98
early pro-B cell	65	0.00	0.69	0.70	0.79	0.00	0.92	0.99	0.99	0.94
pancreatic PP cell	63	0.00	0.17	0.67	0.35	0.00	0.90	0.99	0.98	0.82
basophil	60	0.28	0.61	0.76	0.81	0.00	0.75	0.97	0.82	0.85
ciliated columnar cell of tracheobronchial tree	61	0.80	0.87	0.96	0.86	0.00	0.88	0.99	0.93	0.98
dendritic cell	54	0.45	0.26	0.77	0.64	0.00	0.91	0.91	0.84	0.81
ependymal cell	49	0.00	0.70	0.97	0.85	0.00	0.95	1.00	1.00	0.98
Bergmann glial cell	52	0.00	0.45	0.86	0.76	0.00	0.77	1.00	1.00	0.96
pulmonary interstitial fibroblast	45	0.41	0.59	0.76	0.74	0.00	0.92	1.00	0.94	0.95
pancreatic stellate cell	45	0.88	0.47	0.93	0.48	0.00	0.86	0.90	0.89	0.95
regulatory T cell	43	0.00	0.00	0.12	0.04	0.00	0.68	0.90	0.91	0.44
pericyte	34	0.00	0.77	0.72	0.82	0.00	0.84	0.96	0.94	0.93
fibrocyte	35	0.00	0.00	0.40	0.41	0.00	0.60	0.76	0.82	0.87
respiratory basal cell	28	0.00	0.00	0.89	0.74	0.00	0.68	0.95	0.98	0.96
plasma cell	23	0.16	0.00	0.75	0.16	0.00	0.25	0.45	0.36	0.43
club cell	20	0.00	0.00	0.22	0.17	0.00	0.26	0.91	0.44	0.57
kidney interstitial fibroblast	15	0.00	0.00	0.64	0.85	0.00	0.83	0.86	0.97	1.00
lymphoid lineage restricted progenitor cell	11	0.00	0.00	0.90	0.91	0.00	0.69	0.63	1.00	0.95
intermediate monocyte	12	0.00	0.00	0.25	0.13	0.00	0.91	1.00	1.00	0.50
lymphocyte	9	0.00	0.00	0.20	0.00	0.00	0.76	1.00	1.00	0.20
lung macrophage	8	0.00	0.00	0.22	0.00	0.00	0.44	0.89	0.80	0.93
plasmacytoid dendritic cell	6	0.00	0.00	0.00	0.00	0.00	0.63	0.43	0.86	0.67
lung neuroendocrine cell	4	0.00	0.00	0.86	0.86	0.00	1.00	0.89	1.00	0.86

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