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(1) The cell growth of E.coli DH5α follow logistic growth kinetics with an assigned growth constant µ. (2) For simplicity decay of all products follows first-order kinetics. (3) All promoters have the same activity resulting in a constant transcription rate. (4 ) The rate of translation is considered to be equal yet the degradation rate of proteins differs. (5 )AHL transport is only restricted by diffusion through the cell membrane following the concentration gradient, AHLout > AHLin. (6) Binding and dissociation constants of AHL and luxR are based on mass-action kinetics. (7) The enzymatic activity of LuxI within the fusion protein is not decreased by the fusion event. In a first simple model a single cell and its kinetics in output will be analyzed. The major input in this simplified scenario is AHL produced from SAM catalyzed by LuxI. The direct output is GFP or any other fluorescent reporter like RFP and YFP. In the gene design it can be seen that GFP expression is coupled to its induction upon binding of LuxR-AHL complex to the luxR promoter. Next, AHL has to be transported across the membrane of the cell via diffusion. The inside concentration is therefore determined by the diffusion rate across the membrane (kdif), the initial concentration (AHLex) as well as the decay constant of AHL inside the cell (kAHL). Furthermore AHL as well as constitutively expressed LuxR form a complex which can bind to the luxR promoter. The amount of AHL-LuxR complex binding the luxR promoter is dependent on the concentration of AHL, the concentration of LuxR and its degradation (kLuxR) the binding and dissociation constant of AHL and LuxR (kdis=. A signal can be detected using different reporters like fluorescent proteins, pigments or substances that can be detected. We focused on the detection using fluorescent proteins like GFP which could be detected using absorbance measurements. In this easy model the kinetics of GFP as output signal will be displayed. The formula displays GFP expression over time G(t). The term X(t) refers to the mRNA production and degradation as well as fluorescent read out obtained in RFU, composed of kt x M, where kt is an unknown constant and M is mRNA production remaining constant for all proteins expressed in our model. The Term γ stands for dilution rate which can also be represented by the growth rate µ of the E.coli Dh5α. The half life of GFP was experimentally determined to be around 24 hours. Therefore the value of γ is about 0.029 h-1 and can be neglected as it is so much smaller than dilution rate. For the simulation first the model of a growing culture with direct AHL input and GFP output was analyzed. The three graphs shown below demonstrate the behavior of the gene construct upon AHL induction. The higher the concentration of AHL used for the induction the higher is also the fluorescence signal detected from GFP. AHL diffuses basically without any constriction into the bacteria clearly depicted by the exponentially following decay of the graphs (Figure 1). Correspondingly the endpoint fluorescent signals of GFP vary depending on the AHL input which can be seen in Figure 2. For high AHL concentrations the endpoint GFP signal is elevated compared to lower AHL concentrations. In Figure 3 the LuxR-AHL complex formation is displayed which also increases in endpoint value for increased AHL concentrations caused by the availability of binding partner. Even this simplified model shows that the output GFP signal can be used to quantify the amount of AHL present in the sample. This will allow us in the future to accurately determine the amount of cancer cells present in the patient's blood sample. Using amplification constructs like introducing LuxI downstream of the Lux pR together with a reporter protein even more AHL will be produced. The set-up can be seen in Figure 4.
Every year I love attending the Greek food festival! The food is yummy and the music and dancing are fun. It is fun to see the crowd join in the traditional dances. Then, the kids come out and steal your hearts.
Participants will hear from industry experts like Dr. Benjamin Anderson, Professor of Surgery, Division of General Surgery from the University of Washington School of Medicine; Dr. Karin Rodland, Director and Professor, Biological Sciences Division, Pacific Northwest National Laboratory; Dr. Peter Dirks, Senior Scientist and Neurosurgeon, Garron Family Chair in Childhood Cancer Research, The Hospital for Sick Children, Professor of Surgery and Molecular Genetics, University of Toronto; Dr. Jonas Korlach, Chief Scientific Officer, Pacific Biosciences and Dr. Andrew Ravanelli, Senior R&D Scientist, Genome and Epigenome Editing, MilliporeSigma, to name a few. Cancer research has made major advancements in diagnosis, treatments, and the basic understanding of the disease itself and each year we see a decrease in mortality rates due to a strong focus on learning more about the origination of the disease. Topics for this year's event include Gas Chromatography/Infrared Spectroscopy, Cancer Epigenetics and Natural History, Cancer Microbiome, as well as developments in Cancer Diagnostics. Produced on a new, more robust platform, attendees can watch, learn and connect during this conference on mobile devices easier than ever before, without the travel cost that is normally associated with these types of conference. Equipped with gamification and point system, they can now move around the entire virtual event earning points for a chance to win one of LabRoots most popular shirts. Like other LabRoots events, participants can earn free continuing education credits. Following each presentation, viewers can click on the educational credit link provided for that particular speaker and follow the required process. Once you have completed the process, you will receive a certificate for the educational credit. To learn more about this event, see the complete list of speakers, or to register for free, click here. Participants can join the conversation online by using #LRCancer. LabRoots is the leading scientific social networking website, offering top scientific trending news and premier educational virtual events and webinars. Contributing to the advancement of science through content sharing capabilities, LabRoots is a powerful advocate in amplifying global networks and communities. Founded in 2008, LabRoots emphasizes digital innovation in scientific collaboration and learning. We have become a primary source for trending scientific news, webinars, virtual conferences and more. Offering more than articles and webcasts that go beyond the mundane and explore the latest discoveries in the world of science, LabRoots users can stay atop their field by gaining continuing education credits from a wide range of topics through their participation in the webinars and virtual events.
US1 Crashes a Party Summer Fiction Poetry Summer Fiction Prose Mercer Camps Trenton, NJ (08648) Windy with rain likely. Low 29F. Winds ESE at 20 to 30 mph. Chance of rain 100%. Rainfall may reach one inch. Winds could occasionally gust over 40 mph.. Windy with rain likely. Low 29F. Winds ESE at 20 to 30 mph. Chance of rain 100%. Rainfall may reach one inch. Winds could occasionally gust over 40 mph. Dr. Nicole McGrath Barnes (front row, second from left) and the staff of the KinderSmile Community Oral Health Center on North Broad Street in Trenton. Dr. Nicole McGrath Barnes with a young patient of the KinderSmile Foundation. New Program Brings Bright Smiles to Trenton Kids By Dan Aubrey Dan Aubrey Dec 22, 2021 Updated Jan 9, 2022 "We have treated over 3,000 children and families. You cannot imagine the need in Trenton," says Nicole McGrath-Barnes of the dental services provided by KinderSmile Foundation. "We're not a typical dental practice or Medicaid or hospital. I have created an access to health care for everyone. Not just for a zip code," she adds during a recent talk for the Trenton Symposium. McGrath-Barnes' statement reflects the nonprofit's mission to "provide underserved children with access to comprehensive dental care and educate children and their families about the importance of dental hygiene. We envision a future where every child has access to a dentist and preventable dental diseases are eradicated." In Trenton's KinderSmile office the demographics are primarily black or brown and run the gamut from immigrants to state workers. McGrath-Barnes says the organization uses several different programs. The prime one is the group's Oral Health Program. According to KinderSmile materials, the OHP "increases access to dental care for underserved children ages 0 to 18, regardless of insurance status, by bringing dental care to schools or community centers at no cost to caretakers or the school system." Others include Special Smiles, an expansion of the OHP that provides dental care and oral health education to children with developmental disabilities, the Pre and Postnatal Program dental services and health education for pregnant women and new mothers, and the Community Service Learning Program that mentors and guides high school and college students to participate in oral health professions. Describing her journey from the daughter of a Brooklyn Jamaican immigrant mother to dental professional, McGrath-Barnes says she was inspired by how her mother, with limited schooling, had "taught herself the British education system" and become a legal secretary. In response, McGrath-Barnes says she decided "to educate myself and have a career," adding that when she was 14 she saw an advertisement for a dental assistant and applied. Although the "old Jewish doctor" didn't hire her, he offered to mentor her. The girl accepted and came to the office a few times a week and started to learn the business. Later the graduate of the University of Maryland's School of Dentistry opened a private practice in Bloomfield. After 14 years of practice, she says, "I loved the clinical aspect and relationship with my patients and felt something was missing, and after soul searching and I realized I wasn't involved with the community that I had been part of it. I went on a search and went to Head Start in Montclair and said, 'I'm Dr. McGrath and I want to be a program dentist.' And I said it was pro bono." She says she started showing up on Wednesdays, "the day dentists were off," and talking to children about oral disease prevention — which she calls the easiest disease to prevent. "I loved it. I felt a connection to the community. As things progressed, I noticed children had rapid decay when they smiled. Montclair is affluent, but there is a ward that is below poverty level." The catalyst for creating a larger child-focused dental program happened when she received a call from the receptionist at her dental office about a patient waiting for her at the office. "It was a little girl. She said something about Dr. Nicole. I knew she was from Head Start." McGrath-Barnes says the girl's aunt brought to the office because the girl "had a swelling on the side her mouth the size of a golf ball. It was a nasty, ugly infection. She had it three months and it was in a primary molar. No other dentist would take her because it was Medicaid. She needed to be on antibiotics ASAP and the tooth needed to be extracted. "I went home and said something was wrong. I was led by passion and need, and here I am years later." The KinderSmile Foundation was established in 2007. McGrath-Barnes says she started first as a mobile operation where she traveled to schools and shelters and used disposable materials. She also used her office and began a partnership with the University of Medicine and Dentistry of New Jersey in Newark. She also asked colleagues to participate but was disappointed when they said they "didn't want 'that' population in my office." Then she realized a problem. Even if she found an office, the parents refused to go. "I found out what they believed was that KinderSmile was their provider and didn't want to go anywhere else." She says she consulted with the foundation's board and "we decided to open a brick and mortar spot. In 2015 we opened our first dental home. We call it home so people feel comfortable. She says after KinderSmile developed a partnership with the Boys and Girls Club in Newark, she was invited to participate in a health care program led by Tammy Murphy, the spouse of Governor Phil Murphy. Also attending the session was the director of Capital Health Institute for Urban Care, Dr. Eric Schwartz. He connected McGrath-Barnes with Deborah Sands Gartenberg of the Princeton-based George H. and Estelle M. Sands Foundation. Through her involvement with other area organizations, Gartenberg was aware of the need for Trenton children to have access to affordable oral health care. After she visited the KinderSmile "home" in Newark, she asked McGrath-Barnes to expand their services to Trenton. The Sands Foundation supported the effort with $1.4 million of funding. Other funding comes from Medicaid, other grants, and individual donors. "I didn't know much about Trenton," McGrath-Barnes says. "I took a year and a half to learn about it. And in the thick of the pandemic, we opened our doors in Trenton and expanded our service to treating children and adults." The organization developed a relationship with a Princeton-based oral surgeon who performs oral extractions and forged a partnership with Mercer County Community College to build a dental curriculum and hire dental assistants. She also says she is focusing on something else to help Trenton children by recognizing that "a lot of the women in Trenton are single moms. We believe in focusing on the matriarchs" and "empower the matriarchs in our community." During a quick visit the Trenton offices that opened in 2020 in a Mercer County Community College building, McGrath-Barnes moves through the suites of rooms including offices and open examination rooms. Though it was an off day with one person in the waiting room, a KinderSmile report notes, "Our Trenton office is already bridging the gap in access to oral healthcare for underserved youth and adults in Trenton. Medicaid/NJ FamilyCare insures 63 percent of Trenton's children, yet prior to KSF's expansion into Trenton, there was only one dental practice that accepted that form of insurance, with limited access to uninsured patients. "As of November 2021, the percentage of uninsured we serve is approximately 60 percent, nearly double our pre-opening, heavily data-driven projections. Our very successful and one-of-a-kind Perinatal Health and Wellness program provides education, prevention, and treatment solely to uninsured expectant moms and their newborns." "Most of our patients with insurance are NJ FamilyCare state Medicaid insurance," McGrath-Barnes says in an email exchange regarding payments, especially those without insurance. "If an uninsured patient under 12 years old presents to our dental home, the initial exam, cleaning, x-rays and treatment plan is 'free,' she continues. "For patients 12 and older, adults, is $40. Uninsured emergency patients pay $40 as well. "For continued treatment for the uninsured population, we have extremely reduced fees. The purpose of this is to make access to oral health affordable for all. If an uninsured family or patient cannot afford treatment at all, we apply for grants to help them. Or we assist and encourage them to apply for NJ FamilyCare. No one leaves our dental home without treatment." In a response to the establishment of KinderSmile offices in areas known to be lacking in affordable healthcare, NJ Biz newspaper named McGrath-Barnes a Heathcare Hero in October 2020 and the Princeton Mercer Chamber of Commerce's named her a Woman of Achievement in June 2021. KinderSmile Foundation, 191 North Broad Street, Trenton. For more information on how to use or support KinderSmile resources: 973-744-7003 or www.kindersmile.org. Follow Dan Aubrey Princeton Gastroenterology Associates On the Move: Pickleball, Adare Pharma, and More Summer Camp: The Hot Ticket for 2022 GFS 'Klips' Dark Season With Bright Dreams History & helpful hands in Herrontown Woods Robert Wood Johnson University Hospital Hamilton Walk (Or Bike) This Way New Cheesesteak Joint Gives Something to Chew On NJ Film Festival Starts 40th Season of Screenings Go Inside This Week's Issue of U.S. 1: January 12, 2022 U.S. 1 To view our latest e-Edition, click the image on the left. communitynews.org 9 Princess Road, Suite M Lawrence, NJ 08648 Email: [email protected] © Copyright 2022 Community News Service, LLC, 9 Princess Road, Suite M Lawrence, NJ | Terms of Use | Privacy Policy
Spiritbox have announced a second UK headline show Spiritbox have announced a second UK headline show. The band – who are also over for Download this spring – will now be performing in London on both 13th and 14th June, in support of their debut album 'Eternal Blue', out now via Rise Records. The details are: 12 Download Festival 13 O2 Academy, Islington, London Tickets for the new date go on sale from 10am on Friday, 4th March.
As one of the most desired "holy grail" materials in the EDC world, Titanium is worth its weight and is a fantastic metal to add to your EDC collection. Titanium weighs almost the same as aluminum but is stronger than steel. Its high density and hard oxide layer makes it highly resistant to corrosion even in sea water, aqua regia and chlorine. It is non-toxic, non-allergenic and perfectly compatible with the human body. It is even more durable than gold and has become a popular choice for designer jewelry.
As you know, our first session of Religious Education classes for the Tuesday groups was cancelled due to the changeable weather. The gusts of wind and occasional rain made for potentially hazardous driving conditions and so it seemed prudent to postpone the classes. I guess rather than "snow days" we should simply call them "weather days" when we build flexibility into our schedules for missed school and work. We are excited to get our Religious formation program started again, and are sure many teachers and students were disappointed to postpone their first day back.
Data & Statistics (1) Traditional Water Harvesting Question raised in Lok Sabha on Traditional and Modern System of Rain Water Harvesting, 18/07/2019 Question raised in Lok Sabha on Traditional and Modern System of Rain Water Harvesting, 18/07/2019. Central Ground Water Board is periodically monitoring the ground water levels throughout the Country India is drying up, fast Congratulations to all... we have achieved 50 degree temperature this year. Let's cut more trees to achieve 60 degrees the next year,' a sarcastic tweet the other day came as a jolt. It was, however, Tribune (New Delhi) Churu (D) Ahmedabad (D) Bangalore (T) Augmenting water security and food security of small farmers in Andhra Pradesh, Karnataka and Tamil Nadu in India Across India, the magnitude and intensity of extreme weather events like drought and floods is increasing. Such changes in climatic conditions affect a myriad of issues of which, access to water for drinking Global Water Partnership Sustaining water regimes- The work of Anupam Mishra Anupam Mishra's work on how the indigenous water systems of Rajasthan have sustained a water regime not only made it possible for a robust civilisation to thrive in the desert but along with his writings Anupam Mishra Water conservation: a dying wisdom Disasters challenge system capacities and human intelligence and in most cases bring out the best of human capabilities in dealing with sudden shock with creative and constructive thinking. This is particularly Outcome document of the high-level plenary meeting of the General Assembly known as the World Conference on Indigenous Peoples Outcome document of the high-level plenary meeting of the General Assembly known as the World Conference on Indigenous Peoples - draft resolution submitted by the President of the General Assembly. Question raised in Rajya Sabha on protection of water bodies, 07/07/2014 Question raised in Rajya Sabha on protection of water bodies, 07/07/2014. Land Encroachments Order of the National Green Tribunal regarding rain water harvesting systems in Delhi, 09/12/2013 Order of the National Green Tribunal in the matter of Vikrant Kumar Tongad Vs. Delhi Metro Rail Corporation Ltd. dated 09/12/2013. This matter relates to rain water harvesting systems being entirely non-functional Water Harvesting Techniques Delhi Pollution Control Committee (DPCC) Life in Khunti changes with biodiversity project RANCHI: The Khunti district in the past has been feared for Red terror but there is a success story there too in which the conservation of biodiversity was done by roping the village community. This not Times Of India (Ranchi) Village Level Planning People's perception on Mansagar Lake This paper is part of research on Urban Lake Governance in India which includes in-depth case study of Mansagar Lake Governance. The focus of the paper is on people's perception on social and ecological Birding Fair Jaipur (T) Lake Action Plan Urban Water Harvesting Rural Water Harvesting
It's only when they then pick up the papers that they discover he's stabbed them in the back with a kebab knife. If he can make House of Fraser work perhaps we'll be all be singing from a different hy. The National House-Building Council, the main provider of construction insurance, said builders registered plans to start work on 36,637 new homes in the first quarter, down from 42,405 in the first q. A dog has had to be operated on to remove a skewer it ate when it wolfed down a chicken kebab. The Sharpei called Hoshi underwent life-saving surgery after the eight-inch metal rod became wedged in it. Trump explained in an interview with The Wall Street Journal published Friday that his shift came after White House talks Thursday with Obama. during which he used it to needle rival Hillary Clinto. Don't know if he has travel insurance, but would a transatlantic ship be safer for. cover-every-angle speak but one travel forum writer said that he was asked for one at Enterprise car rental. Do y. The Great Abbreviations Hunt – Stuart Bruce – Total number of As found: 10885 (61%) A B C D E F G H I J K L M N O P Q R S T U V W X Y Z AA AB AC AD AE AF AG AH AI AJ AK AL. But the disqualified driver was seen by a police officer at the wheel of a car in Crook, in January, and, while on bail for that offence, assaulted two police officers as he was being arrested for sma. Maybe that's why none of the London commentariat has noticed what's going on out there in Telford, and Aylesbury, and Kettering. Newcastle. And it's insurance. Reinsurance. Stocks and shares. Futur. Total number of As found: 10885 (61%) A B C D E F G H I J K L M N O P Q R S T U V W X Y Z AA AB AC AD AE AF AG AH AI AJ AK AL. Beetroot shammi kebab (served with lotus seed and mint chutney), campagna. For desserts (most of them made in-house), we opt for the unbeliever's dessert (black sesame cake and kaffir lime coconut. He had been Europe minister between 2010 and last year when he moved across to leader of the House of Commons, a post concerned with the smooth running of the Commons. The Cambridge history graduate a. Defining America – But that's just what CNN is aiming to do – and we need your help! CNN producers from all across the network have come together to create the Defining America project. We were inspired by the 2010 cens. Chairman of the Royal Institution of Chartered Surveyors (RICS) Thomas Dimopoulos put forward another reason for the increase in rents in general: the difficulty of obtaining loans to purchase a house. UK motorists spend 31 hours a year stuck in traffic – costing them almost £1,200 each – MORE: Motorist has car seized by police for not having commuting insurance During peak hours. by the fact that Inrix research put towns such as Bath, Braintree and Aylesbury in the UK's most jammed. Far more damage is done by the pollution, congestion and accidents caused by driving a large car with only a few bags of shopping slung in the back.' On this basis, he adds that supermarket delivery s. Four people have been found dead in Aylesbury Farms apartments on Abbotts Bridge Road. Cobb Patch Two teenagers were killed in East Cobb early Sunday morning when the car in which they were riding.
Submit to the market pages of the NeoCon Show Daily and May 2019 issues by April 5. It is our editorial format to list either the company's legal, copyrighted name or, if more specific, the particular division or subsidiary. We do not list the brand name as the manufacturer. If the company was initially a separate entity and purchased by a new company, we do keep the original name. If a company calls its various labels 'brands' but they are, in fact, separate divisions, then we can include the brand name instead. In some cases, where room permits and at the editor's discretion, we do include a brand/sub-brand within the body text and list the official copyrighted name as a 'through' credit. This is done on a case by case basis, and often depends on space, how the manufacturer listed the product in the press release/submission materials, and whether the writer included the brand in the text. A set of high resolution images (.jpg or .tiff) at least 350 dpi illustrating the project. Please send us a link to download them via Dropbox, WeTransfer, or an image transfer site of your choosing. Floor plans and two or three-dimensional renderings, including measurements, explaining the project. They should be submitted as digital and/or PDF files and included in the download link. A brief description of the project, noting the client's program, your design solution, total square footage and the project cost. If total project cost not available, please give cost per square foot. A complete list of all manufacturers' sources, keyed to the photographs submitted. A brief professional biography of the principal team as well as portraits of the project designers (no more than two principals). We make no publishing commitments without seeing complete professional photography (its quality being a factor in our decision), and we look for images in which the lighting detail is clear: fabric patterns, chair legs, etc. Please note that Interior Design is adamant about exclusivity. The project submitted must not have been published in any magazine as a feature layout in the United States or Canada. It is acceptable that a project may have been mentioned as a news item.
Gravel Events eBike Events Trails – Eastern Cape Trails – Free State Trails – Gauteng Trails – KwaZulu Natal Trails – Limpopo Trails – Mpumalanga Trails – Mountain Passes Trails – North West Trails – Northern Cape Trails – Western Cape Girl On Dirt mtbapp Home ARTICLES News Garden Route mountain bike race now more compact Garden Route mountain bike race now more compact Next month's Garden Route 300 will be "more compact" to offer an even purer mountain biking experience in the Knysna forest from April 28 to 30. The three-stage race, which also occupies a new slot on the calendar, will comprise a feature event over a total of 200km as well as a Lite version of 170km. Race director Patric Mosterd, of Garden Route Events, said by shortening the two races they were able to cut out portions that did not necessarily add value to any of them. "By doing this, we are left with only the good stuff as we pursue a truly pure mountain biking experience." Mosterd said the GR300, as it is known these days, would still remain a genuine test. "Just because it comprises fewer kilometres, does not mean it is any less of a challenge," he said. "Basically it is a case of fewer kilos but more quality and I can assure you that the riders will be pleased to see the finish line each day." He said the more compact stages do however shorten time spent in the saddle, making it more accessible to participants who would have been on the edge of their ability previously. The idea, he said, was that the shorter days would be an additional incentive for prospective participants to try out the Garden Route event for the first time. "We really want to share this gem of a riding area with as many people as possible." With the event initially taking place at the height of summer as a precursor to races like the Cape Epic, Mosterd said there was a feeling that the original distances were just too far for its current slot – especially being in a mountainous area. "We think the event is now doable for a broader spectrum of riders instead of just a select few. We hope many more can now enjoy the experience with us." He said the stage distances of the feature event would be 75km, 50km and 75km. Mosterd said the Lite version, which was introduced three years ago as an alternative to the main race, would also have a facelift. "The first and third stages have been shortened by approximately 15km each as we want to give riders with less mountain biking expertise a chance to catch the vibe and spirit of the occasion." He said it also offered an easier access path into the event for relative novices, who would then be able to upgrade to the feature event in following participations. "We live in a tourist town, which is a holiday destination for many families. We want to create a situation that appeals to everyone." He said they operated the GR300 as "one event", with everyone starting together. "But what happens is that the Lite cuts out the more technical parts and one or two long climbs before re-joining the feature race. "This means family and friends can start together and possibly finish together without all the riders having to do the toughest sections of the course." Mosterd said the distances would be 60km, 50km and 60km with entries being open until the week of the event. "However, there is a cut-off (April 10) for the registration item, which is an outer garment from apparel company Capestorm." Visit www.gardenrouteevents.co.za. Previous articleEntries Open for 2017 Ladismith Cheese 7Weekspoort MTB Challenge Next articleOvercoming the Odds to Take on The 36ONE MTB Challenge Fernhill Frenzy 2020 Wild Mass Start to Crazy Mountain Bike Race in New Zealand Ghosting into Podium Contention Dormakaba red and blue set to strike New sponsorship CST PostNL Bafang Mountainbike Racing Team Beers and Stenerhag Kick-Off 2020 In (Muddy) Style Defending Champions Return to Knysna Bull Follow @@mtbapp Facebook Page Like Send us a mail today! All mountain bike races in one place... MtbApp. Get your friends to join in on races across SA. We designed the App to fulfil an important need for all South African Mountain Bike enthusiasts, and that is to have all the events mobile and accessible with one touch of the App. While travelling around our beautiful country the MtbApp also helps you locate local trails and bike parks, let's face it, if you are a crazy adventurous mountain biker like me, you love to ride on all the various terrains around the country. JOIN US Lucrative prize-money for Winelands Encounter Fedhealth MTB Challenge
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Author: - October 01, 2018 0 Francesco Molinari clinches Ryder Cup glory for dominant Europe over USA Woods twice on Saturday had the misfortune to encounter his recent nemesis Francesco Molinari , who has teamed up with Tommy Fleetwood to go 4-0-0 this week. Europe now has won nine of the last 12. "There was a little moment in the middle of it all where I was getting a little bit anxious, but then everybody stood up and did their bit", Bjorn said. Author: - October 01, 2018 0 Brewers clinch 1st playoff spot since 2011, sweep Cards ET. The Brewers (95-67) already had secured their first playoff appearance since 2011, the last time they won the NL Central. Wild-card games on Tuesday (losers of Brewers-Cubs and Rockies-Dodgers games) and Wednesday (Athletics at Yankees) will narrow the field to eight teams, four in each league, as the chase begins in earnest for the World Series crown. Author: - October 01, 2018 0 Mourinho slams players as West Ham twist the knife A 3-1 loss at West Ham on Saturday means United have taken 10 points from their first seven games of the season, recording their joint worst start to a Premier League season, equalling the beginning of the ill-fated David Moyes era. An unlucky own goal increased their lead but even a superb strike from Marcus Rashford made little difference, with Marko Arnautovic scoring the victor. Author: - October 01, 2018 0 Three takeaways from Ohio State's win over Penn State Then, just like last year's meeting, it was gone. It had Ohio State off balance and was primed to pick up the first, but for some reason the officials stopped play to announce that the Nittany Lions did not get a first down. Although Franklin really didn't say anything to get himself in trouble, he was clearly upset by the remarks. Haskins connected with Binjimen Victor , who weaved and slipped through tacklers for a 47-yard touchdown catch and run that cut it to 26-21 with 6:42 left. Author: - September 30, 2018 0 Manchester City v Brighton - Confirmed Lineups: Pep Guardiola missing star names Mendy had spent Saturday evening at Wembley , watching Anthony Joshua's heavyweight title fight against Alexander Povetkin, and had been due to receive treatment the following morning. I'm not a physio", stressed a visibly unhappy Guardiola . However, Kevin de Bruyne is expected to return to training in the next few days. Sergio Aguero continued his prolific strike rate at The Etihad Stadium as Manchester City warmed up for their important Champions League clash in Hoffenheim ... Author: - September 30, 2018 0 Arsenal beat Watford 2-0 in Premier League tie Leno had to come on for his Premier League debut moments before half-time after Cech limped off. In each of our seven victories, we haven't been that impressive, with the players looking sluggish for periods, but when it matters most, the team has become focused and showed effectiveness. Author: - September 30, 2018 0 Messi and co "angry" after Barca slip up again It was the eighth goal conceded by Barcelona this season - they reached the halfway point of last season having only conceded nine goals. "Of course we need the points", Valverde said, adding, "any team needs the points but for us even more so, because every team Barcelona loses, there is an natural disaster". Author: - September 30, 2018 0 Finau Gets Ryder Cup Nod The U.S. will send Dustin Johnson , Justin Thomas , Brooks Koepka , Webb Simpson , Bubba Watson , Patrick Reed , Jordan Spieth , Rickie Fowler , Woods, Mickelson, DeChambeau and Finau to France. He checked a lot of boxes and made it impossible not to go for him". Those eight players qualified automatically through Ryder Cup points . They have not won successive Ryder Cups since 1993. Author: - September 30, 2018 0 Meadville's Journey Brown scores first college TD Penn State didn't need the passing game to come out with a win, but it did complete clutch passes. Cathey set a new career high in the loss with 15 kills of her own. True freshman quarterback JT Daniels passed for 241 yards and three touchdowns, and Vavae Malepeai rushed for two scores as the Trojans rallied for a Pac-12 Conference victory over the visiting Cougars. Author: - September 30, 2018 0 Pumped Rory McIlroy Roars Striking Message After Ryder Cup Putt Without another miracle, the questions about why the US would mess with a formula that worked so well two years ago will be unavoidable. The Americans gave themselves a glimmer of hope, picking up the final two points. We can play well and nothing can happen. "That's the frustrating thing about matchplay". Both stuck their second shots on the par-four 15th into the water, and Finau finally found his range on 16 to make it a one-hole game. Author: - September 30, 2018 0 1200 fans to make trip of a lifetime to Ryder Cup The United States have not won on European soil since 1993 - the year three of their current team were born. The American team have a combined 31 majors between them - Tiger Woods has 14 to himself - with their European counterparts having won just eight, and Rory McIlroy has half of those as the only multiple victor. Author: - September 30, 2018 0 Man United match worst Premier League start with loss to West Ham Mourinho left the under-performing Alexis Sanchez out of his squad for the trip to the London Stadium and then revealed his decision to start with a back three, including midfielder Scott McTominay, was to accommodate Anthony Martial . Author: - September 30, 2018 0 Jurgen Klopp rushed to Mo Salah after Daniel Sturridge's equaliser Liverpool boss Jurgen Klopp has played down his decision to substitute Mohamed Salah against Chelsea , though admits the Egyptian did not have his best game. "He is a fantastic football player and he had a good pre-season, and he is in the best shape since I know him", Klopp told reporters. "It was not Mo's best game of his career, 100%". Author: - September 30, 2018 0 Intriguing Ryder Cup Sunday Singles Matches Announced He was set to play with Bryson DeChambeau in the afternoon alternate-shot matches, with Reed benched for the rest of the day. "We've seen the scenarios play out over the years". Koepka pulled one back and then Finau's approach on 11 took him to four feet. I think he was exhausted. It allowed him to maybe get some energy back. Author: - September 29, 2018 0 Mourinho on Pogba: 'No player is bigger than the club' A source at the club has revealed that Pogba's behaviour has alarmed the majority of the squad and younger players are struggling to cope with Mourinho criticism. Some trained as well as, nobody better. "Disruptive? I think for you it was wonderful because you made a story, an incredible story out of 15 minutes of an open training session". Author: - September 29, 2018 0 Eden Hazard makes tactical claim on Man Utd boss Jose Mourinho The Belgian came off the bench to score an excellent late solo goal as the Blues clinched a 2-1 Carabao Cup victory at Anfield in midweek, ending Liverpool's ideal start to the season. Hazard said: "The cup game was important for Saturday I think". "The formation was good with the new players and we could add them on to our matchday squad because they all played really good". Author: - September 29, 2018 0 LSU basketball player Wayde Sims, 20, shot to death LSU head coach Will Wade released a brief statement responding to the news. According to authorities, Sims was in a Subway restaurant when shots rang out and he was immediately rushed to the hospital, but ultimately dies from his wounds. "He was on an upward trajectory", Wade said. "You tell your players to stay away from these situations. God bless Wayde Sims ". He was a high school prodigy and was named the Louisiana Gatorade Player of the Year in 2015. Author: - September 29, 2018 0 Emery swerves questions over Ramsey's future at Arsenal BeinSport says United failed with a £50m bid for Ramsey. Ramsey is in the final year of his contract and now looks likely to leave on a free transfer unless he is sold in January at a cut-rate price. Ozil became the best paid player in Arsenal's history back in February after the German playmaker put pen to paper on a deal thought to be worth around £350,000. Author: - September 29, 2018 0 'Mourinho did the right thing, no player is bigger than the club' The transfer was announced at 12.35am on United's social media feeds, using a hashtag "Pogback" while an online music video featuring Pogba and Stormzy - put together by kit sponsor Adidas - quickly went viral. Manchester United next watch is against West Ham at the London Stadium in the early Saturday kick-off. "I think good results, and good performances, they make miracles", said Mourinho at his press conference on Friday before the Premier League match against Wolves. Author: - September 29, 2018 0 Wolves Continue To Seek Return For Jimmy Butler Beyond What Teams Offering They could look to make a three-team trade in order to make the deal happen. The Houston Rockets are reportedly making a push to add Jimmy Butler . He said he wishes Butler "nothing but the best". Until something does happen with Butler though, all focus will remain on training camp in Hawaii, where the Clippers will face off against the Sydney Kings on Sunday, September 30. Author: - September 28, 2018 0 Paul Pogba determined to leave Manchester United next summer Another source has added that only a handful of players from the current squad support Mourinho completely, and that too because the Manchester United board is insistent on fully backing the 55-year-old tactician. "Another question is, should he be getting more out of a £90m player?" Pogba tried to defend himself to Mourinho over the accusations, pointing towards Andreas Pereira and Luke Shaw who also featured in the short clip on Instagram. Author: - September 28, 2018 0 Panthers sign Eric Reid to 1-year deal — National Football League free agency Stills says Kaepernick "wants to play". I think he's a good player. "He deserves to play". After the team announced its signing of Reid, numerous responses on Twitter were excitedly positive. Kaep and Reid were teammates on the 49ers and have been good friends for a WHILE. He said the Panthers "just got better having him on their squad". Author: - September 28, 2018 0 Arsenal striker Welbeck hails 'great player' Smith Rowe Arsenal beat Brentford 3-1 on the night to progress to the next round but it was a memorable night for Yennaris, who was a part of the Arsenal academy growing up. Smith joked: "I was hoping it was going to be Macclesfield at home but unfortunately we've got to travel to the Emirates, which I'm sure all our supporters will be looking forward to". Author: - September 28, 2018 0 Mourinho wants the Manchester United board to back him over Pogba feud He was already in the English capital this week for The Best FIFA awards ceremony on Monday night, so it could also be the opportune time to cement his future employment plans. Paul Pogba's older brother Mathias has joined Tours in the French third tier after spending more than a year without a club. The top officials at the Mancunian outfit are aware of this depressed mood in the dressing room, but they continue to believe that Jose can successfully turn things around and get the team ... Author: - September 27, 2018 0 Tottenham manager Mauricio Pochettino says 'embarrassing' late goal doesn't spoil win Moussa Dembele showed his class in the 23rd minute as he turned well to release Danny Rose , who played a good cross towards Kane's flick-on that was deflected behind for a corner, which came to nothing. The seagulls did make things a little nevery towards the end as Anthony Knockaert fired home in the 93rd minute but it wasn't enough as Spurs held on for the win. < 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499 500 501 502 503 504 505 506 507 508 509 510 511 512 513 514 515 516 517 518 519 520 521 522 523 524 525 526 527 528 529 530 531 532 533 534 535 536 537 538 539 540 541 542 543 544 545 546 547 548 549 550 551 552 553 554 555 556 557 558 559 560 561 562 563 564 565 566 567 568 569 570 571 572 573 574 575 … >
Adam Spector When the Game Stands Tall - An Inspiring Movie from Snap to Whistle Written By: Adam Spector PROMPT: Film Review Competition 2016 ` From the first "snap" of the movie, "When the Game Stands Tall" is an exciting movie and forcefully reminds watchers the meaning of teamwork and accountability. Based on a true story, "When the Game Stands Tall" features the De La Salle High School football team that is famous for its winning streak of over 150 games. The film begins with the team about to win a state championship and extend the streak to 151 games. During this time, the Spartans are led by seniors T.K. Kelly and Cam Colvin, who were able to encourage their teammates to be accountable for and play for one another. In the offseason that followed, events such as the death of Colvin's mother, the murdering of T.K. Kelly and Head Coach Bob Ladoucer suffering a heart-attack foreshadowed a relatively dim future for the De La Salle team. The beginning of the next season was showed the Spartans in a new light, as new players, such as big-shot receiver Tayshon Lanear, were more egocentric and diverted away from the team-centered values that Coach Ladoucer had preached for years. As a result, the team dropped both of their first two contests that season and the coaching staff had to take the team to a VA Hospital where rehabilitating soldiers taught the players the true meaning of team. After that experience, the team quickly bonded and went on to beat the top ranked team in the country and win another state championship. The movie did a superb job of portraying emotions. This was evident during the intense scenes around the death of Cam Colvin's mother, as well as the interactions within the Ladoucer family following Bob Ladoucer's heart-attack. The determination of the Spartans after losing the winning streak was apparent and well portrayed. Also, in the few scenes where in-game dialogue was seen, viewers could see both the self-interested side of some of the players, as well as the desire for teamwork and victory displayed by other players. "When the Game Stands Tall" , however, fell short in giving viewers the in-game interactions between players during the seasons in which T.K. Kelly and Cam Colvin played. Dialogue from those games could have been useful in allowing viewers to see the difference in the older, always victorious teams and the newer, egomaniacal team that ruined the decade-long winning streak. Also, Coach Ladoucer was played as a very calm coach, whereas football coaches are usually loud and intense. Having a robust personality playing Coach Ladoucer may have made the coach seem more realistic. Another area in which this film exceeded was showing the thought that characters put into plot-changing decisions. For example, when Bob Ladoucer realized that his aging message of teamwork was not successful with his new team, he felt unneeded at De La Salle and considered moving to Stanford University. In the end, Ladoucer stayed true to himself and continued conveying the same message to his players. Secondly, when running back Chris Ryan had the opportunity to break the state scoring record and please his demanding father in his final game at DLS, Ryan decided to heed Coach Ladoucer's message and focus on the team rather than individual achievements. The emotions, decisions and lessons that were shown in "When the Game Stands Tall" made the movie a moving viewing experience. After viewing the film, I would most definitely recommend it. As an avid football fan, I found it easy to follow the plot, but viewing the movie does not require too much knowledge of football and the lessons conveyed are applicable to anyone. The plot is engaging and contains very few shortcomings. Share on Facebook Tweet See History January 13, 2016 - 10:06pm (Now Viewing) Reviewed by AdamS10cp Login or Signup to provide a comment.
Has it been almost two months since I posted here? Why yes. Yes it has. I blame the hive of scum and villany that is the Evil Former Employer in which I — somehow, don't ask me how — have become the project manager for my merry little band. In either case, still up to my elbows in that mess which...is no fun. I keep telling myself "this will be worth it in the end...this will be worth it in the end...this will be worth it in the end..." So, what's new with all of you?
Reggio (, ), also known as Bencheque (, ), is an Isleño fishing community located in St. Bernard Parish, Louisiana. The community was established in 1783 with the settlement of Canary Islanders along Bayou Terre-aux-Boeufs. During the last decade of the eighteenth century, Louis de Reggio purchased land from the Isleños to establish a sugarcane plantation. It is perhaps the only community in the United States that bears a Guanche-language name. After the American Civil War, the community greatly expanded as Isleños moved deeper into the eastern portion of the Parish to engage in fishing, trapping, hunting, and Spanish moss gathering. During the twentieth century, forces including urbanization, modernization, improved transportation, and natural disasters among others led to the migration of Isleños away from their traditional communities. Following the complete destruction of Hurricane Katrina, only a handful of the original families returned to rebuild. Etymology and usage The community was originally named for the , a mountain and ravine on the island of Tenerife near Icod de los Vinos where many of the Canary Islander colonists originated. The name comes from the Guanche language and is believed to mean "el lugar de los árboles" (English: the place of the trees) or "lugar de la planta" (English: plant place). An individual from the community is known as a benchecano. The latter name for the community, "Reggio," originates from Louis de Reggio, the owner of the sugarcane plantation that was located in the same area. The distinction between the Reggio plantation and the community of Bencheque had been maintained into the twentieth century. Towards the second half of the twentieth century, "Reggio" came to refer to the former area of the plantation and Bencheque. Isleños, particularly those who know Spanish, maintain this distinction and their descendants continue to do so today. Legal descriptions of land tracts in the settlement use "Bencheque" while "Reggio" has been used by St. Bernard Parish Government, the United States Geological Survey (USGS), and other organizations. History Beginning in 1779, Canary Islanders came to be settled by the Spanish government along Bayou Terre-aux-Beoufs in what would become St. Bernard Parish. The entire settlement was referred to as the Población de San Bernardo (St. Bernard Population) and was composed of various establecimientos (establishments) or puestos (posts), which were smaller communities. These establecimientos ran along Bayou Terre-aux-Boeufs starting just past the western limit of Saint Bernard and extending to Delacroix Island. One of the larger communities, established in 1783, was the quinto establecimiento (fifth establishment) which would come to be known as "Bencheque." In the 1790s, the New Orleanian Louis de Reggio purchased land from the Isleños to establish a sugar plantation. The plantation eventually extended from the Olivier plantation all the way to Wood Lake. In 1836, the Mexican Gulf Railroad was established and linked the Reggio plantation, along with other plantations of St. Bernard Parish, to the city of New Orleans. Following the American Civil War, Isleños began to relocate to Bencheque to fish, trap, hunt, and gather Spanish moss. While changes came to the rest of Louisiana following the Reconstruction era, the Isleños remained largely rural and unchanged. With the turn of the twentieth century, the benchecanos suffered various hardships. The 1915 New Orleans hurricane left many Isleños dead and every house at Bencheque was either badly damaged or completely destroyed. Two years later, the Spanish flu swept through St. Bernard Parish and required the mass burial of over one thousand people, mostly Isleños, at St. Bernard Catholic Cemetery. The Great Mississippi Flood of 1927 and subsequent dynamiting of a levee at Caernarvon left the community completely inundated. Increased urbanization, greater access to education, and improved roads led to residents leaving in search of security and job opportunities. In 1965, Hurricane Betsy made landfall with Louisiana and once again leveled the homes of the community. This event dealt a serious blow to the prevalence of Isleño culture in the traditional Isleño communities of the St. Bernard Parish. In 2005, Hurricane Katrina devastated the region. Very few of the original families returned to the community to rebuild and new ones moved into available property. See also Isleños Canary Islands Guanches Fishing village References Unincorporated communities in Louisiana Unincorporated communities in St. Bernard Parish, Louisiana Louisiana Isleño communities Unincorporated communities in New Orleans metropolitan area
ARTICLE [View FULLTEXT] [Download PDF] Year : 2014 | Volume : 16 | Issue : 68 | Page : 26--33 Prevalence and characteristics of tinnitus after leisure noise exposure in young adults Sofie Degeest1, Paul Corthals1, Bart Vinck2, Hannah Keppler1 1 Department of Speech, Language and Hearing Sciences, Ghent University, Ghent, Belgium 2 Department of Speech, Language and Hearing Sciences, Ghent University, Ghent, Belgium; Department of Communication Pathology, University of Pretoria, Pretoria, South Africa Sofie Degeest Department of Speech, Language and Hearing Sciences, Ghent University, De Pintelaan 185, B-9000 Ghent, Belgium The main goal of this study was to assess the prevalence and characteristics of tinnitus among students after exposure to leisure noise. In addition, the effects of tinnitus on otoacoustic emissions (OAEs) in participants suffering from chronic tinnitus were evaluated. The study consisted of two parts. First, a questionnaire regarding leisure noise exposure and tinnitus was completed. Second, the hearing status of the subjects suffering from chronic tinnitus was evaluated and compared with a matched control group (CG). Furthermore, the psychoacoustical characteristics of their tinnitus in the chronic tinnitus group (TG) were established. The questionnaire was answered by 151 respondents. Seven persons suffering from chronic tinnitus were examined further in the second part of the study. Transient tinnitus was observed in 73.5% of the respondents after leisure noise exposure and 6.6% experienced chronic tinnitus. Transient and chronic tinnitus had similar characteristics, as established by the questionnaire. The amplitude of transient evoked otoacoustic emissions and distortion product otoacoustic emissions was reduced and the amount of efferent suppression was smaller in the TG as compared with the CG. Tinnitus induced by leisure noise is observed frequently in young adults. The characteristics of tinnitus cannot predict whether it will have a transient or rather a chronic nature. In subjects suffering from tinnitus, subclinical damage that cannot be detected by audiometry can be demonstrated by measuring OAEs. These findings underpin the importance of educating youth about the risks of noise exposure during leisure activities. Degeest S, Corthals P, Vinck B, Keppler H. Prevalence and characteristics of tinnitus after leisure noise exposure in young adults.Noise Health 2014;16:26-33 Degeest S, Corthals P, Vinck B, Keppler H. Prevalence and characteristics of tinnitus after leisure noise exposure in young adults. Noise Health [serial online] 2014 [cited 2023 Jan 31 ];16:26-33 Available from: https://www.noiseandhealth.org/article.asp?issn=1463-1741;year=2014;volume=16;issue=68;spage=26;epage=33;aulast=Degeest;type=0
"My God, sir! I never thought it could have gotten this bad this fast!" "Well, the question is: can we clean her up for what we're planning to do with her?" "No way, sir! It would take years. We'll have to start from scratch on a new one." "Then start from scratch we will. You know, I have a new-found respect for the guy, scenery chewing and obvious hair piece notwithstanding." "You're right, sir. Ten years after Captain Kirk steps down, who'd ever expect the Enterprise to look like this?!" Picture prompt above, story below, 90 words and I'm under the limit! I've boldly gone where no Schizophrenic Blogger has ever gone before as well as returned to humor after last week's sojourn in Alfred Hitchcock Presents, yet another vintage TV program. This is my week's contribution to the Fabulous Friday Fictioneers and Flying Federation Starship Society. Click here for lots more from lots of talented folk. Live Long and Prosper, dudes. And beam me out of here, Scotty! :) Inspired take on the prompt! Boldly done. Ha ha!Brilliant!! What insight there! That's funny! I never would have seen the Enterprise in that photo - but I see it now! Made me laugh out loud! Great stuff! The solution: beam it somewhere to a galaxy far, far away! Awesome take on this. I'll have to add your story to those I'll hand deliver to the, er, "car" owner. It runs. I've seen it in two parking lots. Funny stuff! That was so cute. I'm not a big Star Trek fan, but who doesn't know about the Enterprise? I can hear Scotty cursing from the engine room. "Cap'n Block, if I giving her all she can take, any more she's bound to blow" Very inspiring, Perry. I enjoyed this. Yes, start over, there's nothing left! To some, I believe you may have just committed blasphemy. Kepten, I can't hold her any longer. She's going to blow! For sale...only one owner. You beamed me up for a unique take on the prompt. your sense of humor is priceless. another good one Perry. I really enjoyed the ending and the part about the hair piece. ouch. time and deterioration never waits for no man...as we see here. love your fun story. i always love a good shatner joke. well done. help me out - i don't know what you mean by "scenery chewing." is that from a specific episode? also, "notwithstanding" i think should be two words. Scotty.... I need more power!!!! Thank you. Easy as she goes! Thanks! Who'd have suspected Shatner was such a good housekeeper? Brilliant? Now we've got to rebuild an entire new Enterprise for "Next Generation!" Yeah, frankly I'd have given the original a second shot. Sure would have suckered a lot of Klingons into underestimating the Federation. I can't not see it now! And I can see Shatner's toupee right across the front seat. No man with a bottle of Windex anyway. Beth, thanks for the fun prompt! Now that will know about it in junk yards throughout the United States! Well, come to think of it I had kind of a fantasy of getting Dr. Beverly Crusher into the back seat of that jalopy, but I don't think that'll play well for another series. I'll keep at it! And I was just in the mood for a double entendre right about now, Russell. Thank you! Thanks ... wait, does that mean the rest of it sucked? Yep, and for warp speed travel I think that coffee cup would spill. Uh-oh. And I am a true Shatner-fearing person! Ironically Scotty is driving the junker these days. He's actually afraid to "beam up" himself and prefers to drive. Bad ratings from the first series led to this. Anymore every cast member is preserved in amber. Thanks. Always a first time. Other than this, the only place I boldly go is to take out the garbage. Thank you. Is is "priceless.com?" I know. That joke has undone any good I've ever done! Or woman. We both deteriorate equally as well! "Chewing the Scenery" is slang for over-the-top acting, something William Shatner is famous for. No matter - we still love him! No, none of us will ever have much of a life. It's more fun hanging with these guys than real people. And the make-up jobs on them are so much better! Great story and at 90 words, you boldly go where not-many-of-us-have-been-yet. No? I thought I saw you there already packing up from the "clear out" and moving on! oh my The Enterprise is being junked??? No doubt. The four rattling wheels at the bottom are a dead giveaway!
A sublime trilogy in which characters are haunted by the past and bewitched by memories. BEDEVIL is the stunning debut feature from Tracey Moffatt and the first feature directed by an Australian Aboriginal woman. Inspired by ghost stories she heard as a child from both her extended Aboriginal and Irish Australian families, Tracey Moffatt has constructed a sublime trilogy in which characters are haunted by the past and bewitched by memories. All three stories are set in Moffatt's highly stylized, hyper-real, hyper-imaginary Australian landscape.
After the success of out first olympic circlemaking sortie into Wiltshire for the UK newspaper The Sun which they ran on their front cover they asked us to make another more audatious trip to France to create a crop circle backing the London 2012 bid. In keeping with the daring nature of the project we managed to convince BMW to loan us 3 brand new red, white and blue Mini Coopers to travel over to France in ala the movie 'The Italian Job'. The Sun also had some red, white and blue jump suites made for us all to wear during the trip. A crew of 6 circlemakers with a photographer and journalist from the newspaper set off from News International's HQ in Wapping on Friday evening and speeded down to Dover in the Mini's to catch the train over to Calais. On Satuday we got up at the crack and drove to Campigneulles les grandes where we'd managed to find a wheat field to create the formation in. It took around 7 hours to create and when we'd completed it we popped open the champaign The Sun had brought along. We were back in London before sunset. 2 days later, London won the bid to hold the olympics. Above: The completed London 2012 crop circle complete with The Sun logo. Above: The crew pose for photos with the Mini Coopers at News International HQ before setting off for France. Above: The 205ft London 2012 formation with a nearby village in shot. Above: some of the crew looking mean and moody on the train over to France. Photo: The Sun, Mark Pilkington
<div> <div style="padding-bottom: 15px;"> <p style="font-weight: bold;">Edit Ingredients</p> </div> <div style="padding-bottom: 20px;"> <a class="add" href='<?php echo site_url(); ?>ingredients'>Back to List</a> </div> <script> function validate() { var message =""; if ($('#name').val() == '' || $('#name').val() == null) { message += 'Name should have a value\n'; } if (message == "") { return true; } else { alert(message); return false; } } </script> <form onSubmit='return validate()' action="<?php echo site_url(); ?>ingredients/doEdit/<?php echo $id; ?>" method="post" accept-charset="utf-8" enctype="multipart/form-data"> <table> <tr> <td><label for='name'>Name</label></td> <td><input type='text' value='<?php echo htmlspecialchars($ingredients['name'], ENT_QUOTES); ?>' id='name' name='name' /></td> </tr> </table> <div style="padding-top: 15px;"> <input class="submit" type="submit" name="" value="Submit" /> <input type='hidden' id='id' name='id' value='<?php echo htmlspecialchars($id, ENT_QUOTES); ?>' /> </div> </form> </div>
Prince Harry and Oprah Winfrey are launching a mental health documentary series together A formidable partnership for a good cause By Olivia Blair Prince Harry and Oprah Winfrey are joining forces for an important reason. The Duke of Sussex has announced he is partnering with the television mogul to create and produce a mental health documentary series for Apple TV which will launch in 2020. Kensington Palace said the multi-part series, which has been in the works for a few months, will focus on mental illness as well as 'mental wellness' and will aim to inspire viewers to discuss mental health conditions and what we need to do to thrive openly. The Duke And Duchess Of Cambridge And Prince Harry Launching Heads Together In 2016 Nicky J SimsGetty Images 'I truly believe that good mental health – mental fitness – is the key to powerful leadership, productive communities and a purpose-driven self,' the Duke of Sussex said in a statement. 'It is a huge responsibility to get this right as we bring you the facts, the science and the awareness of a subject that is so relevant during these times. We are excited to announce that The Duke of Sussex and Oprah Winfrey are partners, co-creators and executive producers on their forthcoming mental health series launching on Apple in 2020. The pair have been developing the series for several months and are looking forward to sharing such an important project on this global platform. The dynamic multi-part documentary series will focus on both mental illness and mental wellness, inspiring viewers to have an honest conversation about the challenges each of us faces, and how to equip ourselves with the tools to not simply survive, but to thrive. This commitment builds on The Duke of Sussex's long-standing work on issues and initiatives regarding mental health, where he has candidly shared personal experience and advocated for those who silently suffer, empowering them to get the help and support they deserve. His Royal Highness has spent many years working with communities throughout the UK and young people across the Commonwealth to break the stigma surrounding mental illness and broaden the conversation of mental wellness to accelerate change for a more compassionate, connected and positive society. Quote from HRH: "I truly believe that good mental health - mental fitness - is the key to powerful leadership, productive communities and a purpose-driven self. It is a huge responsibility to get this right as we bring you the facts, the science and the awareness of a subject that is so relevant during these times. Our hope is that this series will be positive, enlightening and inclusive - sharing global stories of unparalleled human spirit fighting back from the darkest places, and the opportunity for us to understand ourselves and those around us better. I am incredibly proud to be working alongside Oprah on this vital series." A post shared by The Duke and Duchess of Sussex (@sussexroyal) on Apr 10, 2019 at 2:58am PDT 'Our hope is that this series will be positive, enlightening and inclusive – sharing global stories of unparalleled human spirit fighting back from the darkest places, and the opportunity for us to understand ourselves and those around us better. I am incredibly proud to be working alongside Oprah on this vital series which we have been developing together for several months.' Kevin WinterGetty Images Prince Harry, along with the Duke and Duchess of Cambridge, has long been an advocate for reducing the stigma surrounding mental health conditions and encouraging a more open conversation around an issue which affects so many people. In 2017, he launched Heads Together through the Royal Foundation and he has also spoken publicly about his own mental health, including when he had to seek support and therapy after struggling himself. Aside from Winfrey's gravitas in the television world, the businesswoman is also a spokesperson for mental wellness, regularly touching on it in her Super Soul Conversations series. She too has discussed how conditions including clinical depression and schizophrenia have affected 'several people close' to her and encouraged the need for speaking openly about mental health. Winfrey was invited to attend the royal wedding of Prince Harry and Meghan Markle in May and later described it as a 'cultural moment' and an event which left her feeling like 'anything is possible through the power love'. She has also spent time with Meghan's mother Doria Ragland, who she invited to her house last year and gifted a basket of kumquats! 8 proven ways to beat stress From: ELLE UK More From TV & Film Poldark fans loved last night's series premiere How Prince Harry is related to the Romanovs Rylan confirms the return of Supermarket Sweep Emmerdale confirms return for Lisa Riley Rylan Clark-Neal lands new BBC One presenting job BBC releases first look Poldark images Gentleman Jack creator teases season 2 plot Why this could be Jill Halfpenny's darkest role This Morning fans in hysterics over Gino comment Alison Hammond runs from police on This Morning Prince Harry speaks out about Princess Diana's death Meghan and Kate are working together again William and Harry celebrate 'the best mum in the world' in new Princess Diana documentary A Christmas documentary all about Prince Harry has been confirmed Cheeky! Prince Harry nabs leftovers at book launch Is Prince Harry a 'ginger whinger'
Pattern: Violation of hook rule Issue: - ## Description Verifies hook rules: - **Don't call Hooks inside loops, conditions, or nested functions**. Instead, always use Hooks at the top level of your React function. By following this rule, you ensure that Hooks are called in the same order each time a component renders. That's what allows React to correctly preserve the state of Hooks between multiple `useState` and `useEffect` calls. - **Don't call Hooks from regular JavaScript functions**. Instead, you can: - Call Hooks from React function components. - Call Hooks from custom Hooks (we'll learn about them on the next page). By following this rule, you ensure that all stateful logic in a component is clearly visible from its source code. ## Further Reading * [React - Rules of Hooks](https://reactjs.org/docs/hooks-rules.html)
This future Black Hills State guard has been scorching to end the season. He was featured in our "Premier Performers" list last week after posting a triple-double, and makes the POTW list a week later after piecing together two more triple-doubles. Donovan averaged 14.4 points, 13.5 rebounds and 10.5 assists in two Carlisle wins last week. He has triple-doubles in three of his his last five games. Amazing. This extremely skilled Cougars point guard was the best assist-man in 4A last week, and came away with not one, but two double-digit assist games. During a regular season-finale win over Iowa City High, he double-doubled, dishing out 11 assists and scoring 11 points, too. Earlier in the week against Waterloo East he had 10 helpers. With his savvy and vision, it's no wonder he's become one of the state's best assist guys. What a week for the Bobcats senior. His Marshalltown squad only played one game, but that one performance from Appel was good enough to qualify him for this list. Last Friday night, Appel hit a game-winner and his Bobcats beat No. 3 Des Moines North. Marshalltown was just 6-13 coming into the game. Appel was sensational in the win, going for 26 points on 12-16 shooting, 13 rebounds and two blocks. They'll be talking about that one in Marshalltown for years to come. The Dubuque, Senior Rams are flying high right now, and the state's top-ranked 4A squad has looked virtually unstoppable since the return of junior combo-forward Noah Carter. He returned from leg surgery in late-January, and the Rams have not lost since. Last week, in two more Rams wins, Carter averaged 20.5 points on 60 percent shooting, and 6.5 rebounds. He was getting it one on defense, too; and averaged 1.5 blocks and steals in the the Ws. The Davenport West Falcons have been doing their thing in Eastern Iowa this season, and smooth big-man Trey Sampson has been putting together one of the better seasons in the state for his position. Last week, the Falcons (15-6) closed their regular season with two more wins. Sampson was a beast in both, and averaged 13.5 points and 14 rebounds. What's best, is he nabbed 14 offensive rebounds in the two wins.
Celebrate pollinators! Learn how your students and school can take action to support our pollinators. Create habitat on campus, collect data as citizen scientists. Let's talk TRASH! We'll uncover the problems, concerns, and solutions surrounding all our "stuff". Hop on the SCARCE bus for private tours of facilities that make our everyday lives livable. Learn how to bring your first-hand experiences back to the classroom. Teachers - here's your chance to dive into water! Join us for a 5-day behind-the-scenes experience. We'll learn about STEM in our own community from scientists and engineers on the job. Find out more about this hands-on learning opportunity. Did you know we use 500 million disposable straws a day in the US? Straws are one of the top 10 items found during litter clean ups. Take action to reduce your plastic consumption with these tips and alternatives. This month is all about the schools! We highlight Maercker (Westmont), Westmore (Lombard), and Madison (Wheaton) for their eco-achievements. Plan SCARCE programs for Next Year! Our calendar fills up fast - get a jump on planning and reserve your programs early! We're happy to discuss your eco-club or school-wide goals for the year and how we can help. Is this the year you start food scrap composting, re-certify your Earth Flag or go for your Water Quality Flag? Eisenhower Jr. High students get a tour of a sanitary treatment center as part of a Water Field Trip day coordinated through SCARCE. Does your school, district or town have diesel-run vehicles - including school buses - that you are trying to clean up? Apply for funds to reduce emissions and improve air quality. Summer hours are M-F 9am-4:30pm. We are open Saturday June 10th, July 8th, and August 12th from 9am-12pm. We will be bursting at the seams with books and supplies for your classrooms so stop by while you're free! If you have a donation to make, keep in mind, appointments are required for donations of 8+ boxes. The fair will be full of fun, interactive STEM activities: green exhibits, displays, eco-art, upcycled maker-space, eco-presentations, and more! Contact us about making this an extra credit opportunity for your students! SCARCE is participating or hosting events in blue. Thank you to our May Volunteers! Summer is our busy season! We'll have tons to do and would love helpers to unload cars, process, and shelf books & more at SCARCE M-F 9-4:30. Bring your school or non-profit ID!
Google employees speak up against 'censored search engine for China' "We need a seat at the table", employees told the company in an open letter. (Image credit: Image Credit: Turtix / Shutterstock) Google's employees have written an open letter to their company, in protest of reported plans to create a censored search engine for the Chinese market. Even though it seems as the employees have been working on it for some time, it turns out they never knew what they were building, and don't agree with the product. "Most of us only learned about project Dragonfly through news reports in early August," the letter states." Dragonfly is the name of the project that aims to build a search engine for the Chinese market, which would censor some websites and search queries like religion or human rights. "Currently we do not have the information required to make ethically-informed decisions about our work, our projects, and our employment," they added. They urged their company to be more transparent about its work. "We urgently need more transparency, a seat at the table, and a commitment to clear and open processes: Google employees need to know what we're building," the letter says. Google is yet to comment on the matter. The company left China eight years ago, under pressure from the country's censorship laws, and alleged hacking attempts by the government. China is the world's biggest single internet market, but US companies are having a hard time there, with Google, Twitter and Facebook all being banned. Google still has offices there, though. You can read the entire letter here. Image Credit: Turtix / Shutterstock project dragonfly
Forums > Media Coverage & Other Related Materials > Bakersfield Californian 2013/05/10: The question on everyone's mind: Why hasn't video footage of Silva been... Discussion in 'Media Coverage & Other Related Materials' started by M, May 13, 2013. M Muckraker Staff Member The answer is very simple, Mr. Cohn. They tried to seize the evidence so they could destroy it -- it's a very common tactic when police find themselves inadvertently filmed doing something very stupid. On top of that, one of these thumpers (Deputy Ryan Greer) already owes $4.5M to some other folks for a family member (Jose Lucero) that he helped beat to death back in 2010. What's a poor bad cop to do? A greater concern for most local residents should be, "Are these nine animals still out on the streets with guns & badges?" Bakersfield Californian (5/10/2013): The question on everyone's mind: Why hasn't video footage of Silva been released? If the Kern County Sheriff's Department wants to create a culture of transparency in the community, why has video footage of the events before David Sal Silva's death not been revealed yet?​ This is the question Attorney David Cohn, representing the Silva family, is concerned about. And he wants an answer.​ "Those videos that were taken are the most important piece to this case and another main concern is that those videos aren't altered or destroyed by the Sheriff's Department," Cohn, of the firm Chain | Cohn | Stiles said at a news conference at his downtown Bakersfield office Friday.​ ...​ People who say they witnessed the incident as well as Silva's family members described a scene in which deputies essentially were beating a helpless man to death.​ Cohn has sent letters to government agencies requesting that any videos that were collected not be altered or tampered with. He sent the letters, he said, to the Sheriff's Department, California Highway Patrol and Bakersfield Police Department.​ Cohn said he plans to file a civil rights case federal District Court in Fresno next week.​ M, May 13, 2013 Tags: Bakersfield, California, Kern County, David Sal Silva, Ryan Greer, Jose Lucero, Kern County Sheriff's Office, David K. Cohn
* Fix debug related NullPointerException in solr/contrib/ltr OriginalScoreFeature class. * The JSON output of /admin/metrics is fixed to write the container as a map (SimpleOrderedMap) instead of an array (NamedList). * On 'downnode', lots of wasteful mutations are done to ZK. * Fix params persistence for solr/contrib/ltr (MinMax|Standard)Normalizer classes. * The fetch() streaming expression wouldn't work if a value included query syntax chars (like :+-). Fixed, and enhanced the generated query to not pollute the queryCache. * Disable graph query production via schema configuration <fieldtype ... enableGraphQueries="false">. This fixes broken queries for ShingleFilter-containing query-time analyzers when request param sow=false. * SQL AVG function mis-interprets field type. * SQL interface does not use client cache. * edismax with sow=false fails to create dismax-per-term queries when any field is boosted. Furthermore, this release includes Apache Lucene 6.5.1 which includes 3 bug fixes since the 6.5.0 release.
Title 5. GOVERNMENT ORGANIZATION AND EMPLOYEES Part III. EMPLOYEES Subpart D. Pay and Allowances Chapter 59. ALLOWANCES Subchapter IV. MISCELLANEOUS ALLOWANCES 5 U.S. Code SUBCHAPTER IV— MISCELLANEOUS ALLOWANCES § 5941. Allowances based on living costs and conditions of environment; employees stationed outside continental United States or in Alaska § 5942. Allowance based on duty at remote worksites § 5942a. Separate maintenance allowance for duty at Johnston Island § 5943. Foreign currency appreciation allowances [§ 5944. Repealed. Pub. L. 98–164, title I, § 127(b)(1), Nov. 22, 1983, 97 Stat. 1027] § 5945. Notary public commission expenses § 5946. Membership fees; expenses of attendance at meetings; limitations § 5947. Quarters, subsistence, and allowances for employees of the Corps of Engineers, Department of the Army, engaged in floating plant operations § 5948. Physicians comparability allowances § 5949. Hostile fire pay Eligibility of Additional Employees for Reimbursement for Professional Liability Insurance Pub. L. 106–567, title IV, § 406, Dec. 27, 2000, 114 Stat. 2849, as amended by Pub. L. 107–108, title IV, § 404, Dec. 28, 2001, 115 Stat. 1404, provided that: "(a)In General.—Notwithstanding any provision of title VI, section 636 of the Treasury, Postal Service, and General Government Appropriations Act, 1997 [Pub. L. 104–208, div. A, title I, § 101(f)] (5 U.S.C. prec. 5941 note), the Director of Central Intelligence may— designate as qualified employees within the meaning of subsection (b) of that section appropriate categories of employees not otherwise covered by that subsection; and use appropriated funds available to the Director to reimburse employees within categories so designated for 100 percent of the costs incurred by such employees for professional liability insurance in accordance with subsection (a) of that section. "(b)Reports.— The Director of Central Intelligence shall submit to the Select Committee on Intelligence of the Senate and the Permanent Select Committee of Intelligence of the House of Representatives a report on each designation of a category of employees under paragraph (1) of subsection (a), including the approximate number of employees covered by such designation and an estimate of the amount to be expended on reimbursement of such employees under paragraph (2) of that subsection." [Reference to the Director of Central Intelligence or the Director of the Central Intelligence Agency in the Director's capacity as the head of the intelligence community deemed to be a reference to the Director of National Intelligence. Reference to the Director of Central Intelligence or the Director of the Central Intelligence Agency in the Director's capacity as the head of the Central Intelligence Agency deemed to be a reference to the Director of the Central Intelligence Agency. See section 1081(a) and (b) of Pub. L. 108–458, set out as a note under section 3001 of Title 50, War and National Defense.] Pub. L. 106–346, § 101(a) [title III, § 348], Oct. 23, 2000, 114 Stat. 1356, 1356A–33, provided that: "In addition to the authority provided in section 636 of the Treasury, Postal Service, and General Government Appropriations Act, 1997, as included in Public Law 104–208, title I, section 101(f), as amended [set out as a note below], beginning in fiscal year 2001 and thereafter, amounts appropriated for salaries and expenses for the Department of Transportation may be used to reimburse an employee whose position is that of safety inspector for not to exceed one-half the costs incurred by such employee for professional liability insurance. Any payment under this section shall be contingent upon the submission of such information or documentation as the Department may require." Reimbursements Relating to Professional Liability Insurance Pub. L. 104–208, div. A, title I, § 101(f) [title VI, § 636], Sept. 30, 1996, 110 Stat. 3009–314, 3009–363, as amended by Pub. L. 105–277, div. A, § 101(h) [title VI, § 644], Oct. 21, 1998, 112 Stat. 2681–480, 2681–526; Pub. L. 106–58, title VI, § 642(a), Sept. 29, 1999, 113 Stat. 477; Pub. L. 110–161, div. F, title IV, § 429(a), Dec. 26, 2007, 121 Stat. 2151, provided that: "(a)Authority.— Notwithstanding any other provision of law, amounts appropriated by this Act (or any other Act for fiscal year 1997 or any fiscal year thereafter) for salaries and expenses shall be used to reimburse any qualified employee for not to exceed one-half the costs incurred by such employee for professional liability insurance. A payment under this section shall be contingent upon the submission of such information or documentation as the employing agency may require. "(b)Qualified Employee.—For purposes of this section, the term 'qualified employee' means an agency employee whose position is that of— a law enforcement officer; a supervisor or management official; or a temporary fire line manager. "(c)Definitions.—For purposes of this section— the term 'agency' means an Executive agency, as defined by section 105 of title 5, United States Code, any agency or court in the Judicial Branch, and any agency of the Legislative Branch of Government including any office or committee of the Senate or the House of Representatives; the term 'law enforcement officer' means an employee, the duties of whose position are primarily the investigation, apprehension, prosecution, detention, or supervision of individuals suspected or convicted of offenses against the criminal laws of the United States, including any law enforcement officer under section 8331(20) or 8401(17) of such title 5, or under section 4823 of title 22, United States Code; the terms 'supervisor' and 'management official' have the respective meanings given them by section 7103(a) of such title 5, and, with regard to the Judicial Branch, mean a justice or judge of the United States as defined in 28 U.S.C. 451 in regular active service or retired from regular active service, other judicial officers as authorized by the Judicial Conference of the United States, and supervisors and managers within the Judicial Branch as authorized by the Judicial Conference of the United States; "(4) the term 'professional liability insurance' means insurance which provides coverage for— legal liability for damages due to injuries to other persons, damage to their property, or other damage or loss to such other persons (including the expenses of litigation and settlement) resulting from or arising out of any tortious act, error, or omission of the covered individual (whether common law, statutory, or constitutional) while in the performance of such individual's official duties as a qualified employee; and the cost of legal representation for the covered individual in connection with any administrative or judicial proceeding (including any investigation or disciplinary proceeding) relating to any act, error, or omission of the covered individual while in the performance of such individual's official duties as a qualified employee, and other legal costs and fees relating to any such administrative or judicial proceeding; and "(5) notwithstanding the definition of the terms 'supervisor' and 'management official' under section 7103(a) of title 5, United States Code, the term 'temporary fire line manager' means an employee of the Forest Service or the Department of the Interior, whose duties include, as determined by the employing agency— temporary supervision or management of personnel engaged in wildland or managed fire activities; providing analysis or information that affects a decision by a supervisor or manager about a wildland or managed fire; or directing the deployment of equipment for a wildland or managed fire. "(d)Applicability.— The amendments made by this section [this note] shall take effect on the date of the enactment of this Act [Sept. 30, 1996] and shall apply thereafter." [Pub. L. 110–161, div. F, title IV, § 429(b), Dec. 26, 2007, 121 Stat. 2152, provided that: "The amendment made by subsection (a) [amending section 101(f) [title VI, § 636] of Pub. L. 104–208, set out above] shall take effect on the date of enactment of this Act [Dec. 26, 2007]." [Pub. L. 106–58, title VI, § 642(b), Sept. 29, 1999, 113 Stat. 477, provided that: "The amendment made by subsection (a) [amending section 101(f) [title VI, § 636] of Pub. L. 104–208, set out above] shall take effect on October 1, 1999, or the date of the enactment of this Act [Sept. 29, 1999], whichever is later."
Pubblicò importanti opere su ecologia, orticoltura e storia naturale. Biografia Poco si sa dell'infanzia di Bradley a parte un precoce interesse per il giardinaggio e il fatto che viveva nelle vicinanze di Londra, una città all'epoca con molti naturalisti dilettanti. Sebbene Bradley non avesse un'istruzione universitaria, la sua prima pubblicazione, Treatise of Succulent Plants, gli fece guadagnare popolarità con influenti mecenati come James Petiver e più tardi Hans Sloane. Con il loro sostegno, fu proposto ed eletto nel 1712, all'età di 24 anni, Fellow della Royal Society. Nel 1714 Bradley visitò i Paesi Bassi e si interessò all'orticoltura. Trascorse il decennio successivo in Inghilterra a scrivere trattati su argomenti naturalistici, come il clima, i fertilizzanti, la produttività e l'ibridazione delle piante. In riconoscimento del suo lavoro sul campo e con la promessa - poi non mantenuta - che avrebbe fondato e finanziato un giardino botanico universitario, l'Università di Cambridge nominò nel 1724 Bradley suo primo professore di botanica, una posizione che avrebbe ricoperto fino alla sua morte. Poiché Bradley non era un uomo ricco, e poiché si trattava di una posizione non molto salariata, l'accademico di nuova costituzione continuò a concentrare la maggior parte dei suoi sforzi sul guadagnarsi da vivere con l'editoria. Secondo il suo rivale e successore John Martyn, così come l'altro suo successore, il figlio Thomas Martyn, Bradley lo fece a spese dei suoi studenti, ai quali si dice abbia trascurato persino di tenere lezioni. Bradley fece notevoli innovazioni e scoperte in una vasta gamma di discipline. Ad esempio, il saggio New Improvements of Planting and Gardening includeva indicazioni per la realizzazione e l'uso di un caleidoscopio rudimentale per aiutare nella progettazione e nella disposizione del giardino formale. Scrisse anche di cucina e fu il primo a pubblicare ricette in lingua inglese utilizzando l'allora esotico ananas come ingrediente principale. La sua History of Succulent plants fu il trattato seminale sull'argomento, e i suoi studi sui tulipani e sulle auricole aiutarono ulteriori teorie accurate sulla riproduzione delle piante. Bradley fu anche un pioniere nell'esame della germinazione delle spore fungine e dell'impollinazione delle piante da parte degli insetti. Le sue pubblicazioni contenevano inoltre informazioni su come costruire e utilizzare le serre, prime teorie sulla produttività agricola e sull'ecologia dei laghetti. L'opera più duratura di Richard Bradley potrebbe essere nello studio delle malattie infettive. Quando molti scienziati erano ancora attaccati agli ideali della filosofia meccanica, Bradley si rivolse a studi ed esperimenti empirici per il suo lavoro. Sebbene diffusa in una manciata di suoi documenti, quando presi insieme, emerge una teoria biologica unificata delle malattie infettive che abbracciano tutta la vita: dalle piante, dagli animali fino all'uomo. Opere Treatise of Succulent Plants, 1710. New Improvements of Planting and Gardening, 1719–1720. A Philosophical Account of the Works of Natur, 1721. The Plague at Marseilles Considered, 1721. A General Treatise of Husbandry and Gardening, 1721-1723. (apparso in quindici numeri e successivamente raccolto in tre volumi dal 1721 al 1724) Ten Practical Discourses Concerning Earth and Water, Fire and Air, as They Relate to the Growth of Plants, 1727. The Country Housewife and Lady's Director, c.1727. A Course of Lectures upon the Materia Medica, Ancient and Modern, 1730. Note Altri progetti Collegamenti esterni Voce di database presso la Royal Society Membri della Royal Society Professori dell'Università di Cambridge
Q: Messenger in Visual Studio After i restart laptop, visual studio don't turn off, then i open it again, It shows many lines on tabs. "Feature 'Asset synchronization' is currently unavailable due to an internal error. Show Stack Trace" A: Do these things: * *Press Alt + Ctrl + Del *Select Task Manager. *Click on "More details" on the left side below of the Task Manager. *Then, click the Start button. *Find Visual Studio in this list, then click on it. *Click "Disable" after right-clicking on Visual Studio. Then close the window, and your problem will be solved.
Home Business Lyft Is Best After Having A Comparison Among E-Scooters Companies Lyft Is Best After Having A Comparison Among E-Scooters Companies Ryan Wales E-scooter is new but an emerging sector where the majority of the companies are still startups and trying their best to make a product that will sell and liked by customers. However, in a recent survey done by an expert, he tried four companies e-scooter, namely; Lyft, Uber, Lime, and Bird. After riding each companies scooter and driving for quite a long mile, the analysts declared Lyft's scooter is best among them. This experiment was done in a little chaotic city of Los Angeles, where e-scooter companies are getting a response. Analysts said Lyft's scooter is perfect when it comes to acceleration the scooter offers an exceptional smoothness; it also gave a good response on rough surfaces. There are cities like New York which have banned riding e-scooters because of rising traffic issues. However, in LA, things are quite demanding for e-scooters because love to ride them because of the easiness they offer. Out of these four e-scooters, Lime received the worst review, and the analyst said riding Lime e-scooter was one of his worst decisions. Uber and Lyft, both companies, released their e-scooters for the general public at the same time. However, when he tried to ride on Uber's e-scooter, the driver faced some problems with break and comfort. Uber's e-scooters have too many sensitive breaks as compared to Lyft, and it offered a slightly bumpier ride on the streets of LA. A few months ago, during summer, Uber released their e-scooters in the market made by a Chinese company and received a good response. At last, Bird's e-scooters offered the same level of satisfaction as Uber's, but the only drawback it had was weak brakes. The breaks of Birds scooter were too hard to control and required more energy. But in the end, this small survey gave the award of the best e-scooter to Lyft. Previous articleLamborgini and Rivian Cars Will Soon Have Alexa Voice Control Next articleNASA is all set to ferry its massive rocket part on Mississippi River on a barge Ryan has been part of our editorial team. He has a keen interest in the latest technologies. He prefers scripting articles based on Technology, including new arrivals, ongoing trends in the industry, and much more. Her articles are precise and authentic, along with a comprehensive approach. If not writing, you can find her tasting some of the unique cuisines in the locality. Ryan being a destination gazer loves to explore new places. Inclusive Comprehension 2020: Bio-Butanol Market (Trending PDF) Addressing Structure, Scope, Potential, and Growth Prospects Till 2029 Zoom Blamed in Lawsuit of Inadequately Sharing User Information with Facebook Spiral Membrane Market New Business Opportunities and Investment Research Report 2029 Precast Concrete Market New Business Opportunities and Investment Research Report 2029 Intumescent Coatings Market New Business Opportunities and Investment Research Report 2029 Trump Attacked GM Over Trade War And Employment Issue Addiction Experts of NJ Warns New York for Addiction of Online... 4 Ways You Can Turn Your Side Hustle Into Business
CCR Focus Aurora Kinases as Anticancer Drug Targets Oliver Gautschi, Jim Heighway, Philip C. Mack, Phillip R. Purnell, Primo N. Lara Jr. and David R. Gandara Oliver Gautschi Jim Heighway Philip C. Mack Phillip R. Purnell Primo N. Lara David R. Gandara DOI: 10.1158/1078-0432.CCR-07-2179 Published March 2008 The human aurora family of serine-threonine kinases comprises three members, which act in concert with many other proteins to control chromosome assembly and segregation during mitosis. Aurora dysfunction can cause aneuploidy, mitotic arrest, and cell death. Aurora kinases are strongly expressed in a broad range of cancer types. Aurora A expression in tumors is often associated with gene amplification, genetic instability, poor histologic differentiation, and poor prognosis. Aurora B is frequently expressed at high levels in a variety of tumors, often coincidently with aurora A, and expression level has also been associated with increased genetic instability and clinical outcome. Further, aurora kinase gene polymorphisms are associated with increased risk or early onset of cancer. The expression of aurora C in cancer is less well studied. In recent years, several small-molecule aurora kinase inhibitors have been developed that exhibit preclinical activity against a wide range of solid tumors. Preliminary clinical data from phase I trials have largely been consistent with cytostatic effects, with disease stabilization as the best response achieved in solid tumors. Objective responses have been noted in leukemia patients, although this might conceivably be due to inhibition of the Abl kinase. Current challenges include the optimization of drug administration, the identification of potential biomarkers of tumor sensitivity, and combination studies with cytotoxic drugs. Here, we summarize the most recent preclinical and clinical data and discuss new directions in the development of aurora kinase inhibitors as antineoplastic agents. A defining characteristic of the malignant tumor cell is inappropriate growth. This aberrant behavior is accompanied by invasion into surrounding tissues and metastases to distant sites. The tumor cell phenotype is the consequence of a relatively high level of genetic instability, with sequential mutational and epimutational damage conferring growth and/or survival advantages to the tumor-initiating cell and its evolving progeny. The mechanism of action of established and novel [reviewed in this issue (1–4)] cytotoxic chemotherapeutic agents essentially rests on the exploitation of tumor cell cycling to facilitate the preferential killing of tumor over normal host cells that are critical to survival. This selective killing may be achieved either by interfering with the synthesis/replication of DNA (e.g., using agents such as fluoropyrimidines, gemcitabine, or topoisomerase inhibitors), by the introduction of irresolvable lesions into the DNA of proliferating cells (e.g., platinum analogues and cyclophosphamide), or by disruption of the microtubule cytoskeleton essential for mitotic division (e.g., taxanes, Vinca alkaloids, and epothilones). Given that certain populations of normal and important cells also proliferate in adult tissues (e.g., in the bone marrow), it is not surprising that such cytotoxic agents are associated with some degree of severe normal tissue toxicity. Recent tumor genomics data, however, are now assisting in the development of more rationally selected drugs that target proteins expressed exclusively or at particularly high levels in tumor compared with essential normal adult cells. It is hoped that the specific pharmaceutical targeting of such proteins will result in a new generation of highly active drugs that are associated with minimal collateral host toxicity. We should also recognize, however, that given the underlying nature of the disease and the technology applied, many of the gene products so identified in analyses of expression in tumor versus normal tissue are likely to be intimately associated with the proliferative state and, further, that pharmacologic agents targeting such molecules may therefore again essentially represent a general targeting of proliferating cells. Tumor selectivity would in this case most likely rest on any indirect differential effects of removing target function in the tumor versus critical normal host cells (5). Indeed, proteins intimately involved in the regulation of the cell cycle (6), particularly cell cycle–associated kinases (7, 8), have been suggested as possible new anticancer targets. Although the topic for this issue of CCR Focus is new cytotoxic compounds, the distinction between cytotoxic and cytostatic, and even between chemotherapy and targeted therapy, is perhaps of less importance and with perhaps less underlying biological rationale in 2008 than it was previously. In fact, targeted agents, such as epidermal growth factor receptor inhibitor or antiangiogenic tyrosine kinase inhibitors, do shrink tumors in some patients (i.e., a cytotoxic effect), whereas emerging data suggest that exploitation of the molecular targets of standard chemotherapy (e.g., using ERCC1 as a predictive biomarker for platinum compounds) is now an achievable goal in the clinic. In this review, we will consider the hypotheses that aberrant expression of two serine-threonine mitotic kinases, aurora A (encoded by AURKA on 20q13.2-13.31) and aurora B (encoded by AURKB on 17p13.1), contributes to the neoplastic phenotype; that aurora kinases are appropriate drug targets; and that inhibitors of these particular aurora kinases can add to the cancer therapeutic armamentarium, whether viewed as cytotoxic antineoplastics or as targeted agents capable of modulating the cytotoxicity of contemporary chemotherapy regimens. Aurora Kinases The aurora family comprises three related kinases that share the highest degree of sequence homology in their catalytic domains (9, 10). Expression of aurora A and B is closely linked to the proliferation of many, if not all, cell types, whereas for aurora C, the normal function of which is not clear, expression seems to be restricted to normal testicular tissue (11). Experimental data suggest that inappropriately high or low levels of aurora kinase activity are linked to genetic instability (12). Despite their sequence homology and common association with cycling cells, the subcellular distribution, partners, and substrates and therefore functions of aurora A and B are essentially nonoverlapping (Fig. 1; see refs. 8, 9, 12–14 for reviews). Cell cycle execution points and targets of aurora A and B kinases. Substrates phosphorylated in each phase of the cell cycle by each kinase are detailed, with orange circles denoting targets of aurora A and green circles denoting targets of aurora B. Orange/green line, known substrates of the single yeast aurora kinase IpI1p. Adapted with permission from Macmillan Publishers Ltd: Oncogene (13), 2005. Aurora A has well-established but perhaps not yet fully understood roles in centrosome function and duplication, mitotic entry, and bipolar spindle assembly. By the G2 phase of the cell cycle through anaphase, it can be detected in the pericentriolar material. Additionally, it spreads to mitotic spindle poles and midzone microtubules during metaphase (9). Following activation by the LIM protein ajuba in G2, aurora A phosphorylates and recruits several microtubule-associated proteins to the centrosome to promote maturation. After the breakdown of the nuclear envelope, inactive cytoplasmic aurora A is transported to the proximal ends of the microtubules and activated by the spindle protein TPX2, where it plays an as yet not fully defined role in the Ran-spindle assembly process (9, 13). Aurora A is also linked to the process of G2-M transition, with suppression of expression leading to G2-M arrest and apoptosis and ectopic expression leading to bypass of the G2-M DNA damage-activated checkpoint in model systems (15, 16). In experimental murine models, overexpression of aurora A was found to be oncogenic (17, 18). Aurora B is the catalytic component of the chromosomal passenger complex, which is composed of three additional noncatalytic subunits that direct its activity: survivin, INCEP, and borealin. The chromosomal passenger complex orchestrates the accurate segregation of the chromatids at mitosis, histone modification, and cytokinesis (19). Aurora B and its chromosomal passenger complex partners are associated with the centromeres from prometaphase to metaphase. After chromatid separation, they relocate to the midzone and remain at the midbody until the completion of cytokinesis (9). Aurora B function has been linked to chromatin modification in relation to the phosphorylation of histone H3 at Ser10 and Ser28 (20), events that may be required for chromosome condensation. Through the phosphorylation of MCAK, this kinase also has a crucial role in the regulation of accurate chromatid separation, with aurora B activity ensuring that mitosis does not proceed until all chromosomes have bipolar undertension attachments (21). Aurora B is also thought to be involved in the recruitment of spindle checkpoint proteins to the kinetochores. Finally, this kinase has a critical role in cytokinesis, with depletion resulting in polyploidy cells as a consequence of cytokinesis failure (9). High-level expression of aurora B in model systems has been linked to chromosome instability (22, 23). Aurora C does not seem to have a role in mitosis in the majority of normal cells, with expression essentially restricted to the testes. Localizing in a similar pattern to aurora B, it is thought that aurora C is also a catalytic chromosomal passenger protein. Indeed, it has been shown that aurora C can rescue aurora B–depleted cells, suggesting some significant overlap in function (24). It is therefore thought likely that aurora C has a specific role in the regulation of chromosome segregation during male meiosis (25). Aurora Kinases as Anticancer Targets: Preclinical Data In a wide range of tumor types compared with essentially nonproliferating matched normal tissue, aurora A is strongly expressed at high frequency. This high level of expression is often associated with amplification of the region of chromosome 20 encoding AURKA (Table 1), indicating that deregulated expression of at least one gene in the amplified region provides a survival/proliferation advantage to the tumor cell and is therefore linked directly to neoplasia. In contrast, the chromosomal region encompassing AURKB does not seem to be amplified to a high level in tumors, although low-level copy number increases have been noted in non–small cell lung cancer (NSCLC; ref. 26). The AURKB gene, however, has also been shown to be strongly expressed in many tumor types compared with essentially nonproliferating matched normal tissue, with expression levels often correlating with disease characteristics or outcome (Figs. 2 and 3; Table 1). For example, we determined the expression of both aurora A and aurora B by immunohistochemistry in 33 patients with previously untreated, advanced NSCLC (Fig. 2).4 Our study revealed strong nuclear staining for aurora A (Fig. 2A) and aurora B (Fig. 2B) in 12 (36%) and 7 (21%) cases, respectively. Furthermore, aurora A positivity correlated with aurora B positivity (P = 0.01, Fisher's exact test) and with p53 overexpression (P = 0.05). When considering such data, it should be noted that the differential expression of a gene in tumor compared with normal tissue per se may be a poor indicator of causal involvement in neoplasia, given that this expression may simply be appropriate for the current physiologic state of the tumor cells. This may be particularly relevant in the context of cell cycle–associated genes such as aurora kinases, which are dramatically up-regulated in highly proliferating compared with nonproliferating cells. Thus, elevated AURKA or AURKB tumor expression may be an indicator of rapid cell division, an effect rather than a cause of the malignant phenotype. Such a possibility is supported by the concurrent up-regulation of both AURKA and AURKB transcription observed in tumors (26). In addition, to show that AURKB is strongly expressed in the majority of NSCLC cases with high-level expression of the gene correlating with poor survival and tumor genetic instability, however, we have also shown that, in most informative cases, this expression seems to be driven from one chromosomal allele (26). These observations are consistent with the hypothesis that up-regulation of the gene occurs through somatically acquired cis-located genetic damage, implicating aberrant deregulated expression of AURKB in NSCLC carcinogenesis. Aurora C expression has also been noted in some tumor cell lines, but the significance of this observation is not yet clear (11). Aurora kinases in cancer Coexpression of aurora A and aurora B in lung cancer. Representative aurora immunohistochemistry in NSCLC, showing coexpression of aurora A (A) and aurora B (B). Bar, 50 μm. (O. Gautschi et al., unpublished data). Prognostic significance of aurora B expression in lung cancer. Aurora B mRNA levels in 39 patients with NSCLC were quantified by real-time reverse transcription-PCR. Patients with excessive (above median) expression had a significantly (P = 0.028, Kaplan-Meier curve, log-rank test) poorer survival than patients with moderate (below median) expression. Adapted with permission from Macmillan Publishers Ltd: British Journal of Cancer (26), 2005. It would seem that activating mutations of aurora kinase genes are rare in human tumors (27). Several studies, however, have suggested that commonly occurring gene polymorphisms of AURKA and AURKB are associated with cancer risk or clinical outcome among diverse ethnic groups (Table 1). Although these data imply that differences in functionality or basal expression levels of these kinases may modify risk, perhaps through marginally increasing the level of genetic instability in normal cells (12), they do not provide additional supportive evidence for aurora kinases as potentially effective anticancer drug targets. In some ways, such a statement may seem to be counterintuitive. Yet, when considering such data, we must discriminate between the process of carcinogenesis and the therapeutic utility of targeting a particular protein in an established tumor. For example, if a particular base change alters gene function in such a way as to marginally increase the chance of genetic instability in a particular cell type, this genotype may strongly modify the lifetime risk of tumorigenesis for a carrier. Despite being strongly implicated in elevated cancer risk, however, the gene product may still not be an effective anticancer drug target in relation to the clinical treatment of recognizable disease. Simply, once the horse has gone, fixing the lock on the stable door will not bring it back. The clearly established involvement of aurora kinases in the process of mitosis and the strong circumstantial evidence suggesting that deregulated expression of aurora A and B is linked to tumorigenesis spurred the drive to identify pharmacologically active small-molecule inhibitors of these kinases. The compounds identified reacted with more than one kinase subtype or else were specific for one or other aurora kinase (Table 2). In vivo studies with several of these agents were promising, showing that they were able to bring about a profound inhibition of tumor growth in a range of model systems (28–30). Coupled with the genomic data, such studies provided a strong rationale to underpin subsequent clinical investigations. As is generally the case, however, it was not clear from the preclinical data whether aurora kinase inhibitors, if clinically active in humans, would function primarily as cytotoxic (associated with tumor cell death and response) or cytostatic (associated with growth inhibition and disease stabilization) agents. Ultimately, this question could only be addressed in clinical studies. Aurora kinase inhibitors in clinical development Inhibitors of Aurora Kinases Of the many aurora-selective small-molecule inhibitors currently undergoing preclinical and clinical assessment, only the clinically most advanced inhibitors are briefly discussed here, whereas many other promising members of this new drug class are in development (Table 2). MK-0457 (VX-680) is a pyrimidine derivative with affinity for aurora A, B, and C at nanomolar concentrations. MK-0457 prevents cytokinesis but allows cells to progress through the other stages of mitosis, which leads to polyploidy and, in some cancer cell lines, massive apoptosis. In preclinical models, MK-0457 blocked tumor xenograft growth and induced tumor regressions (28). In its first phase I clinical trial, MK-0457 was given as an i.v. continuous infusion over several days to patients with previously treated solid tumors (31). The principal dose-limiting toxicity (DLT) was grade 3 neutropenia, accompanied by some nonspecific side effects, including low-grade nausea and fatigue. Disease stabilization was observed in one patient with lung cancer and in one patient with pancreatic cancer. Single-agent efficacy studies in lung cancer and colorectal cancer are ongoing. AZD1152 is a quinazoline prodrug, which is converted in plasma into its active metabolite AZD1152-HQPA, which in turn has high affinity for aurora B and C. The effects of AZD1152-HQPA in cancer cells are comparable with MK-0457 (30). In preclinical models, AZD1152 significantly inhibited the growth of human tumor xenografts. In a phase I clinical trial, AZD1152 was given as a weekly 2-h infusion to patients with advanced, pretreated solid tumors (32). DLT was grade 3 neutropenia, with few nonhematologic toxicities. Pharmacokinetic studies confirmed rapid conversion of AZD1152 into AZD1152-HQPA. Three patients had stable disease (melanoma, nasopharyngeal carcinoma, and adenoid cystic carcinoma). Follow-up studies are ongoing with biweekly and continuous infusions, based on preclinical tumor models, which suggested that prolonged drug administration significantly increased the proapoptotic effect of AZD1152-HQPA. PHA-739358 is a pan-aurora (A, B, and C) inhibitor with documented antitumor activity in multiple tumor xenograft models, which have shown sustained tumor growth inhibition after discontinuation of treatment. The results of two phase I dose-escalation studies are available (33). The first study tested 6-h i.v. infusions on days 1, 8, and 15 on a 4-week cycle in patients with advanced, pretreated solid tumors. In a preliminary assessment, DLT was reported to be grade 3 to 4 neutropenia. No tumor responses were observed, but 8 of 40 patients had stable disease for at least 4 months. Pretreatment and posttreatment skin biopsies showed down-regulation of phosphorylated histone H3 Ser10 levels in eight of nine patients tested. The second study tested 24-h infusions in a 2-week cycle. Again, DLT was reported to be grade 3 to 4 neutropenia. Nonhematologic toxicities, including fatigue, pyrexia, and diarrhea, were mild. Although no objective tumor responses were observed, 11 of 40 patients achieved disease stabilization. Posttreatment skin biopsies showed decreased phosphorylated histone H3 Ser10 levels in four of five patients tested. The recommended phase II dose was 500 mg/m2 without granulocyte colony-stimulating factor, whereas further dose escalation with filgastrim support is currently being investigated. MLN8054 was the first orally available aurora kinase inhibitor and the first aurora A–selective inhibitor to enter human clinical trials. This compound induced mitotic accumulation and spindle defects and inhibited proliferation in multiple human cancer cell lines (34). Growth of human tumor xenografts in nude mice was inhibited after oral administration at well-tolerated doses, and the tumor growth inhibition was sustained after discontinuation of treatment. In xenografts, MLN8054 induced mitotic accumulation and apoptosis. The preliminary results of a phase I dose-escalation study are interesting for several reasons (35). Oral MLN8054 (daily on 7 consecutive days, 21-day intervals) was rapidly absorbed and displayed dose-proportionate exposure. DLT was found to be reversible grade 3 somnolence and no profound myelosuppression occurred. This was consistent with animal studies, which showed that MLN8054 binds to the γ-aminobutyric acid α 1 benzodiazepine receptor and causes reversible somnolence. Three human patients with metastatic colorectal cancer received eight cycles of treatment consistent with stable disease. Importantly, immunohistochemical analysis of skin biopsies did not show significant accumulation of cells in mitosis, suggesting incomplete target inhibition. Based on these results, the study is now escalating twice-daily dosing of MLN8054 over 14 days, with the coadministration of methylphenidate. Whether aurora A or aurora B is the better anticancer drug target is a matter of debate (8). At least two groups have directly addressed this question in the laboratory. Warner et al. (36) compared the effects of aurora A and aurora B antisense oligonucleotides in pancreatic cancer cells and found that aurora A–targeted therapy may be preferable to aurora B targeting, as shown by mitotic arrest and the rapid induction of apoptosis. Girdler et al. (37) compared the effects of RNA interference and small molecules targeting aurora A versus aurora B in colon cancer cells and found that the cells tested were extremely sensitive to aurora B inhibition. Interestingly, dual inhibition of aurora A and B results in phenotypes identical to inactivation of aurora B alone (28). Using RNA interference experiments, Yang et al. (38) showed that inactivation of aurora B indeed bypasses the requirement for aurora A and leads to polyploidy, indicating that aurora B is responsible for mitotic arrest in the absence of aurora A. With the emergence of a large number of aurora kinase inhibitors, it will be interesting to see which, if any, of the currently available agents will have the requisite degree of antitumor activity in patients or merit further clinical development. Harrington et al. (28) showed that MK-0457 targets the FLT3 kinase and thereby ablated colony formation in primary acute myelogenous leukemia cells with FLT3 internal tandem duplications. Giles et al. (39) recently reported on the induction of clinical remission with MK-0457 in three patients with BCR-ABL–positive, pretreated leukemia and showed that MK-0457 blocked the T315I-mutant BCR-ABL kinase in these patients. These cases document the first objective responses to a kinase inhibitor in the T315I-mutant BCR-ABL and spurred ongoing clinical trials with MK-0457 in leukemia. The results also indicate that, analogous to sorafenib (which was initially designated as a RAF inhibitor and then later was found to additionally block angiogenesis), off-target effects may add to the successful clinical development of aurora kinase inhibitors. Further, we propose that the lack of objective tumor regression in early clinical trials of aurora kinase inhibitors in solid tumors warrants alternative assessments of antitumor activity in the phase II setting, such as the use of disease control rate (response rate plus stable disease), time-related end points, or randomized discontinuation study designs. This is especially relevant in the context of recent observations that some targeted agents (e.g., sorafenib and erlotinib) induced modest tumor regressions in phase II trials but have subsequently shown to improve survival outcomes in randomized phase III trials (40, 41). Are the aurora kinase inhibitors cancer specific? Clearly, given that they are key regulators of mitosis, they are not, in the strictest sense. Indeed, neutropenia was the primary dose-limiting phase I toxicity in several studies, suggesting that these agents have collateral antiproliferation toxicity on the bone marrow. Aurora kinase inhibitors have also been shown to induce polyploidy in normal mammary epithelial cell cultures (42), raising the issue of long-term clinical effects. Clinical tolerability has generally been good, however, and no severe mucositis, peripheral neuropathy, diarrhea, or alopecia has been observed. One question for the future will therefore be: are there tumors that are exceptionally sensitive to such compounds, enabling delivery of minimally toxic doses that have significant antitumor effects? The identification of biomarkers predictive of clinical benefit for a particular drug in a particular patient may therefore be critical in relation to the effective development of new anticancer agents. In the future, it is likely that many new classes of biological marker, including mutational, epimutational, gene expression, and functional assays, will affect clinical decisions relating to which drug to use, at which dose, and in which patient. The collection of material to facilitate such studies will become increasingly important, especially in the larger clinical trials. The importance of biomarkers in evaluating the question of whether a drug hits a cellular target has also become increasingly accepted in oncology. This is especially true for newer drugs that may be associated with minimal toxicity and where the maximum tolerated dose may not be reached in phase I studies. One particularly attractive feature of the development of aurora kinase inhibitors is the availability of functional biomarkers of target effect. Analysis of phosphorylated histone H3 Ser10 levels can show the effects of both aurora A and aurora B inhibitors (Fig. 4). Because aurora A inhibition results in accumulation in mitosis, levels of phosphorylated histone H3 Ser10 may increase. In contrast, aurora B inhibition is expected to decrease the levels of phosphorylated histone H3 Ser10 because this is a direct substrate of aurora B kinase. As indicated by the translational study for PHA-739358 mentioned previously, confirmation of this as a sensitive and specific biomarker in clinical samples could offer the potential to bring a predictive biomarker to the clinic (33). Additional biomarkers have also been proposed. For example, Gizatullin et al. (43) studied the effect of cell cycle control on the effect of MK-0457 in cell lines from lung, breast, and colon cancer and found that a defective p53-p21 pathway was associated with increased sensitivity. Galvin et al. (44) reported on the use of the aurora A-T288 autophosphorylation site as pharmacodynamic markers for MLN8054. Mitotic index measurements coupled with the aurora A-T288 autophosphorylation site was a direct marker of aurora A activity in tumor and skin biopsies. These studies represent significant advances in the development of clinical biomarkers for aurora kinase inhibitors. Thus, predictive markers, and markers that allow determination of whether a drug is able to reach the target in a given patient, offer a great chance to achieve the truly individualized therapy that academic oncologists have imagined for the future. Induction of characteristic phenotypes by different aurora kinase inhibitors. A, in the A549 NSCLC cell line, aurora A–specific inhibitor MLN8054 induces monopolar spindles (inlay, green color), circular chromatin (inlay, purple color), and accumulation in mitosis (increased 4N peak in flow cytometry, increased phosphorylated histone H3 Ser10 staining). (O. Gautschi et al., unpublished data.) B, in contrast, aurora B/C–specific inhibitor ZM447439 in the A549 cell line allows for progression through mitosis, decreases phosphorylated histone H3 Ser10 staining, blocks cytokinesis, and induces polyploidy (appearance of 8N peak in flow cytometry). Reproduced from the Journal of Cell Biology, 2003;161:267-80. Copyright 2003 The Rockefeller University Press. Several promising drug combinations, including aurora kinase inhibitors, are emerging. Setting the stage, Hata et al. (45) showed the synergistic enhancement of taxane activity in the presence of aurora A RNA interference in pancreatic cancer cells. Yang et al. (46) found that knockdown of aurora A by RNA interference reduced phosphorylated AKT levels and sensitized ovarian cancer cells to cisplatin. Sun et al. (47) described similar results in ovarian and lung cancer cells exposed to MK-0457 plus etoposide. Lee et al. (48) again described additive toxicity with MK-0457 and doxorubicin in prostate cancer cells, whereas Tanaka et al. (49) reported significantly enhanced docetaxel activity by aurora A short hairpin RNA in esophageal cancer xenografts in vivo. Tao et al. (50) showed preliminary data indicating that AZD1152 increased radiosensitivity in vivo and that this effect was p53 and cell cycle dependent. How aurora kinase targeting interacts with chemotherapy and radiation at the molecular and cell cycle level remains to be determined, but these results are very encouraging and will affect the design of clinical studies with aurora kinase inhibitors in the near future. Genetic instability is a key driver of carcinogenesis, and there is ample evidence to suggest that deregulation of aurora kinases contributes to the acquisition of genetic aberrations, promoting the development of malignancy. The importance of aurora kinases as anticancer targets remains to be defined by ongoing clinical trials. Current trials are also aiming to define optimal drug schedules and to maximize target inhibition. At present, no predictive biomarker is available to select patients for treatment with an aurora kinase inhibitor, and further progress in this area is needed. Accumulating preclinical data point toward additive or even synergistic anticancer effects between aurora kinase inhibitors and conventional chemotherapy, and much hope lies on the translation of such combinations into the clinic. We thank Millennium Pharmaceuticals (Cambridge, MA) for providing MLN8054, Dr. R. Gandour-Edwards (University of California Davis Medical Center, Sacramento, CA) for interpretation of the immunohistochemistry, and Dr. K. Chansky (Southwest Oncology Group Statistical Center, Seattle, WA) for statistical analysis. Grant support: Swiss National Science Foundation (O. Gautschi), Swiss Cancer League (O. Gautschi), AstraZeneca Pharmaceuticals (O. Gautschi), and Millennium Pharmaceuticals (P.C. Mack and P.N. 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Increased mitotic phosphorylation of histone H3 attributable to AIM-1/aurora-B overexpression contributes to chromosome number instability. Cancer Res 2002;62:5168–77. Hontz AE, Li SA, Lingle WL, . Aurora A and B overexpression and centrosome amplification in early estrogen-induced tumor foci in the Syrian hamster kidney: implications for chromosomal instability, aneuploidy, and neoplasia. Cancer Res 2007;67:2957–63. Sasai K, Stenoien DL, . Aurora-C kinase is a novel chromosomal passenger protein that can complement aurora-B kinase function in mitotic cells. Cell Motil Cytoskeleton 2004;59:249–63. Tang CJ, Lin CY, Tang TK . Dynamic localization and functional implications of aurora-C kinase during male mouse meiosis. Dev Biol 2006;290:398–410. Smith SL, Bowers NL, Betticher DC, . Overexpression of aurora B kinase (AURKB) in primary non-small cell lung carcinoma is frequent, generally driven from one allele, and correlates with the level of genetic instability. Br J Cancer 2005;93:719–29. Greenman C, Stephens P, Smith R, . Patterns of somatic mutation in human cancer genomes. Nature 2007;446:153–8. Harrington EA, Bebbington D, Moore J, . VX-680, a potent and selective small-molecule inhibitor of the aurora kinases, suppresses tumor growth in vivo. Nat Med 2004;10:262–7. Soncini C, Carpinelli P, Gianellini L, . PHA-680632, a novel aurora kinase inhibitor with potent antitumoral activity. Clin Cancer Res 2006;12:4080–9. Wilkinson RW, Odedra R, Heaton SP, . AZD1152, a selective inhibitor of aurora B kinase, inhibits human tumor xenograft growth by inducing apoptosis. Clin Cancer Res 2007;13:3682–8. Rubin EH, Shapiro GI, Stein MN, . A phase I clinical and pharmacokinetic (PK) trial of the aurora kinase (AK) inhibitor MK-0457 in cancer patients [abstr 3009]. J Clin Oncol 2006;24 (June 20 Supplement). Schellens JH, Boss D, Witteveen PO . Phase I and pharmacological study of the novel aurora kinase inhibitor AZD1152. J Clin Oncol 2006;24:122s. De Jonge M . A phase I dose-escalation study of PHA-739358 administered as a 6-hour infusion on days 1, 8, and 15 every 4 weeks in patients with advanced/metastatic solid tumors. Presented at the VIII Congress of the Italian Association of Medical Oncology (AIOM), November 18, 2006, Milan, Italy. Manfredi MG, Ecsedy JA, Meetze KA, . Antitumor activity of MLN8054, an orally active small-molecule inhibitor of aurora A kinase. Proc Natl Acad Sci U S A 2007;104:4106–11. Jones SF, Cohen RB, Dees EC, . Phase I clinical trial of MLN8054, a selective inhibitor of aurora A kinase. Proc Am Soc Clin Oncol Annu Meet 2007;25:3577. Warner SL, Munoz RM, Stafford P, . Comparing aurora A and aurora B as molecular targets for growth inhibition of pancreatic cancer cells. Mol Cancer Ther 2006;5:2450–8. Girdler F, Gascoigne KE, Eyers PA, . Validating aurora B as an anti-cancer drug target. J Cell Sci 2006;119:3664–75. Yang H, Burke T, Dempsey J, . Mitotic requirement for aurora A kinase is bypassed in the absence of aurora B kinase. FEBS Lett 2005;579:3385–91. Giles FJ, Cortes J, Bergstrom D, Kantarjian H . MK-0457, a novel kinase inhibitor, is active in patients with chronic myeloid leukemia or acute lymphocytic leukemia with the T315I BCR-ABL mutation. Blood 2007;109:500–2. Shepherd FA, Rodrigues Pereira J, Ciuleanu T, . Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005;353:123–32. Escudier B, Eisen T, Stadler WM, . Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 2007;356:125–34. Ditchfield C, Johnson VL, Tighe A, . Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores. J Cell Biol 2003;161:267–80. Gizatullin F, Yao Y, Kung V, Harding MW, Loda M . The aurora kinase inhibitor VX-680 induces endoreduplication and apoptosis preferentially in cells with compromised p53-dependent postmitotic checkpoint function. Cancer Res 2006;66:7668–77. Galvin KM, Huck J, Burenkova O, . Preclinical pharmacodynamic studies of aurora A inhibition by MLN8054. Proc Am Soc Clin Oncol Annu Meet 2007;24:13059. Hata T, Furukawa T, Sunamura M, . RNA interference targeting aurora kinase A suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells. Cancer Res 2005;65:2899–905. He L, Kruk P, Nicosia SV, Cheng JQ . Aurora-A induces cell survival and chemoresistance by activation of Akt through a p53-dependent manner in ovarian cancer cells. Int J Cancer 2006;119:2304–12. Sun C, Chan F, Briassouli P, Linardopoulos S . Aurora kinase inhibition downregulates NF-κB and sensitises tumour cells to chemotherapeutic agents. Biochem Biophys Res Commun 2007;352:220–5. Lee EC, Frolov A, Li R, Ayala G, Greenberg NM . Targeting aurora kinases for the treatment of prostate cancer. Cancer Res 2006;66:4996–5002. Tanaka E, Hashimoto Y, Ito T, . The suppression of aurora-A/STK15/BTAK expression enhances chemosensitivity to docetaxel in human esophageal squamous cell carcinoma. Clin Cancer Res 2007;13:1331–40. Tao Y, Zhang P, . Enhancement of radiation response in p53-deficient cancer cells by the Aurora-B kinase inhibitor AZD1152. Oncogene. 2007 Dec 17 [Epub ahead of print]. Tanaka T, Matsunaga K, Fukada D, Mori H . Centrosomal kinase AIK1 is overexpressed in invasive ductal carcinoma of the breast. Cancer Res 1999;59:2041–4. Miyoshi Y, Iwao K, Egawa C, Noguchi S . Association of centrosomal kinase STK15/BTAK mRNA expression with chromosomal instability in human breast cancers. Int J Cancer 2001;92:370–3. Hoque A, Carter J, Xia W, . Loss of aurora A/STK15/BTAK overexpression correlates with transition of in situ to invasive ductal carcinoma of the breast. Cancer Epidemiol Biomarkers Prev 2003;12:1518–22. Royce ME, Sahin AA, . STK15/aurora-A expression in primary breast tumors is correlated with nuclear grade but not with prognosis. Cancer 2004;100:12–9. Xu HT, Qi FJ, . Expression of serine threonine kinase 15 is associated with poor differentiation in lung squamous cell carcinoma and adenocarcinoma. Pathol Int 2006;56:375–80. Vischioni B, Oudejans JJ, Vos W, Rodriguez JA, Giaccone G . Frequent overexpression of aurora B kinase, a novel drug target, in non-small cell lung carcinoma patients. Mol Cancer Ther 2006;5:2905–13. Zhu J, Firozi PF, . Overexpression of oncogenic STK15/BTAK/aurora A kinase in human pancreatic cancer. Clin Cancer Res 2003;9:991–7. Chieffi P, Cozzolino L, Kisslinger A, . Aurora B expression directly correlates with prostate cancer malignancy and influence prostate cell proliferation. Prostate 2006;66:326–33. Comperat E, Camparo P, Haus R, . Aurora-A/STK-15 is a predictive factor for recurrent behaviour in non-invasive bladder carcinoma: a study of 128 cases of non-invasive neoplasms. Virchows Arch 2007;450:419–24. Fraizer GC, Diaz MF, Lee IL, Grossman HB, Sen S . Aurora-A/STK15/BTAK enhances chromosomal instability in bladder cancer cells. Int J Oncol 2004;25:1631–9. Tong T, Zhong Y, Kong J, . Overexpression of aurora-A contributes to malignant development of human esophageal squamous cell carcinoma. Clin Cancer Res 2004;10:7304–10. Yang SB, Zhou XB, Zhu HX, . Amplification and overexpression of aurora-A in esophageal squamous cell carcinoma. Oncol Rep 2007;17:1083–8. Araki K, Nozaki K, Ueba T, Tatsuka M, Hashimoto N . High expression of aurora-B/aurora and Ipll-like midbody-associated protein (AIM-1) in astrocytomas. J Neurooncol 2004;67:53–64. Zeng WF, Navaratne K, Prayson RA, Weil RJ . Aurora B expression correlates with aggressive behaviour in glioblastoma multiforme. J Clin Pathol 2007;60:218–21. Jeng YM, Peng SY, Hsu HC . Overexpression and amplification of aurora-A in hepatocellular carcinoma. Clin Cancer Res 2004;10:2065–71. Zhao X, Li FC, Li YH, . [Mutation of p53 and overexpression of STK15 in laryngeal squamous-cell carcinoma]. Zhonghua Zhong Liu Za Zhi 2005;27:134–7. . [Deletion of p15 and p16 genes and overexpression of STK15 gene in human laryngeal squamous cell carcinoma]. Zhonghua Yi Xue Za Zhi 2003;83:316–9. Reiter R, Gais P, Jutting U, . Aurora kinase A messenger RNA overexpression is correlated with tumor progression and shortened survival in head and neck squamous cell carcinoma. Clin Cancer Res 2006;12:5136–41. Qi G, Ogawa I, Kudo Y, . Aurora-B expression and its correlation with cell proliferation and metastasis in oral cancer. Virchows Arch 2007;450:297–302. Sorrentino R, Libertini S, Pallante PL, . Aurora B overexpression associates with the thyroid carcinoma undifferentiated phenotype and is required for thyroid carcinoma cell proliferation. J Clin Endocrinol Metab 2005;90:928–35. Lassmann S, . Predictive value of aurora-A/STK15 expression for late stage epithelial ovarian cancer patients treated by adjuvant chemotherapy. Clin Cancer Res 2007;13:4083–91. Landen CN, Lin YG, Immaneni A, . Overexpression of the centrosomal protein aurora-A kinase is associated with poor prognosis in epithelial ovarian cancer patients. Clin Cancer Res 2007;13:4098–104. Kurahashi T, Miyake H, Hara I, Fujisawa M . Significance of aurora-A expression in renal cell carcinoma. Urol Oncol 2007;25:128–33. Bodvarsdottir SK, Hilmarsdottir H, Birgisdottir V, Steinarsdottir M, Jonasson JG . Aurora-A amplification associated with BRCA2 mutation in breast tumours. Cancer Lett 2007;248:96–102. Sen S, White RA . A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines. Oncogene 1997;14:2195–200. Nishida N, Nagasaka T, Kashiwagi K, Boland CR, Goel A . High copy amplification of the Aurora-A gene is associated with chromosomal instability phenotype in human colorectal cancers. Cancer Biol Ther 2007;6:525–33. Reichardt W, Jung V, Brunner C, . The putative serine/threonine kinase gene STK15 on chromosome 20q13.2 is amplified in human gliomas. Oncol Rep 2003;10:1275–9. Klein A, Zang KD, Meese E . Overexpression and amplification of STK15 in human gliomas. Int J Oncol 2004;25:1789–94. Neben K, Korshunov A, Benner A, . Microarray-based screening for molecular markers in medulloblastoma revealed STK15 as independent predictor for survival. Cancer Res 2004;64:3103–11. Zhang RD, . Amplification/overexpression of a mitotic kinase gene in human bladder cancer. J Natl Cancer Inst 2002;94:1320–9. Sato S, Kitajima S, . Overexpression of aurora-A potentiates HRAS-mediated oncogenic transformation and is implicated in oral carcinogenesis. Oncogene 2005;24:1122–7. Moreno-Bueno G, Sanchez-Estevez C, Cassia R, . Differential gene expression profile in endometrioid and nonendometrioid endometrial carcinoma: STK15 is frequently overexpressed and amplified in nonendometrioid carcinomas. Cancer Res 2003;63:5697–702. Chen J, Amos CI, . Association between aurora-A kinase polymorphisms and age of onset of hereditary nonpolyposis colorectal cancer in a Caucasian population. Mol Carcinog 2007;46:249–56. Hienonen T, Salovaara R, Mecklin JP, Jarvinen H, Karhu A . Preferential amplification of AURKA 91A (Ile31) in familial colorectal cancers. Int J Cancer 2006;118:505–8. Ewart-Toland A, de Koning JP, . Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human. Nat Genet 2003;34:403–12. Lo YL, Yu JC, Chen ST, . Breast cancer risk associated with genotypic polymorphism of the mitosis-regulating gene aurora-A/STK15/BTAK. Int J Cancer 2005;115:276–83. Vidarsdottir L, Tryggvadottir L, Eyfjord JE . Breast cancer risk associated with AURKA 91T→A polymorphism in relation to BRCA mutations. Cancer Lett 2007;250:206–12. Cox DG, Hankinson SE, Hunter DJ . Polymorphisms of the AURKA (STK15/aurora kinase) gene and breast cancer risk (United States). Cancer Causes Control 2006;17:81–3. Tchatchou S, Wirtenberger M, Hemminki K, . Aurora kinases A and B and familial breast cancer risk. Cancer Lett 2007;247:266–72. Kimura MT, Mori T, Conroy J, . Two functional coding single nucleotide polymorphisms in STK15 (aurora-A) coordinately increase esophageal cancer risk. Cancer Res 2005;65:3548–54. Gu J, Gong Y, Huang M, Lu C, Spitz MR . Polymorphisms of STK15 (aurora-A) gene and lung cancer risk in Caucasians. Carcinogenesis 2007;28:350–5. Ju H, Cho H, Kim YS, . Functional polymorphism 57Val>Ile of aurora kinase A associated with increased risk of gastric cancer progression. Cancer Lett 2006;242:273–9. Dai Q, Gao YT, . Aurora-A/STK15 T+91A is a general low penetrance cancer susceptibility gene: a meta-analysis of multiple cancer types. Carcinogenesis 2005;26:1368–73. Thank you for sharing this Clinical Cancer Research article. You are going to email the following Aurora Kinases as Anticancer Drug Targets Message Subject (Your Name) has forwarded a page to you from Clinical Cancer Research Message Body (Your Name) thought you would be interested in this article in Clinical Cancer Research. Clin Cancer Res March 15 2008 (14) (6) 1639-1648; DOI: 10.1158/1078-0432.CCR-07-2179 Endpoints for Immuno-oncology Trials Limitations and Challenges in Immuno-oncology Trials Developing Early-Phase Combination Immunotherapy Trials Show more CCR Focus
There has been so much controversy in the past few years about the benefits of stem cell research or the lack of benefits of stem cell research. This is especially true when you are talking about embryonic stem cell research. It seems that everyone has an opinion on this subject. With the strides made in the medical community, these days there are more benefits of stem cell research than ever before. 1. Stem cells can be coaxed to produce a bio degradable organ or tissue. 2. There is a possibility of a reduction of tooth decay. 3. With continued research there will be more of a stem cell cancer treatment. This gives doctors the possibility of saving thousands of lives. 4. In some studies stem cells have been shown to help manage diabetes. One day there could be a stem cell diabetes cure. This is wonderful news for the millions that suffer from type I or type II diabetes. 5. There will be a stem cell treatment for heart disease. 6. Stem cell hair regrowth treatment. There has been some progress on for male pattern baldness on mice; hopefully the same will be true on humans in the near future. 7. With more research stem cells could help cure Parkinson's disease. 8. With more research it may slow down the progression or stop Alzheimer's altogether. 9. There will be a stem cell treatment for autism. 10. May help lessen the impact and damage caused by strokes. This is just the tip of the iceberg. With continued research everyone can see the benefits of stem cell research. Instead of trying to stop stem cell research, we need to put more of an effort into this research. In the long run many lives will be saved.
Fly with the portable device of your choice and Garmin-caliber GPS data at the same time. GLO for Aviation brings you the best of both worlds by combining GPS/GLONASS receivers with Bluetooth® technology so you can get precise position information on your iPad, iPhone or Android device.GLO for Aviation can receive position information from both the GPS and GLONASS satellite constellations, allowing it to connect to up to 24 more satellites than devices that rely on GPS alone. This allows GLO to lock on to satellites approximately 20% faster and keep up with even the most demanding jet speeds. What's more, GLO updates its position information 10x per second – up to 10x more often than the GPS receivers in many mobile devices. When you access geo-referenced charts, Garmin SafeTaxi or the moving map display in Garmin Pilot (6 months of which come free with your GLO purchase), you'll know that what you see is the most precise picture possible.Using Bluetooth® technology, GLO for Aviation wirelessly pairs to your mobile device. Just use the included mount to set GLO on your glare screen and within moments, you'll be receiving GLO's position data. The device features up to 12 hours of battery life to keep your position on even the longest of flights, and charging GLO between uses is a cinch with the included USB cable or 12/24 Volt cigarette lighter adapter. In our on the web HilalT LLC you will find a large variety of Garmin GLO for Aviation. The variety of online store is actually expanding. This is the 4. pages. We'll be happy to last high quality. Looking for presented a lot of modern Garmin GLO for Aviation and gadgets that will not cause indifferent.
Whether you are finally replacing that 80-pound TV you bought so long ago, or simply looking for the best TV wall mount for the new TV you are going to buy during Black Friday, getting the right mount for your unique set up is important. From fixed, tilt, and full motion to MantelMount and ceiling mounts, when it comes to finding the best TV wall mount, many people don't know where to start. On the surface, mounting a TV to your wall seems like a good idea. It saves space, adds style, as well as flexibility by lifting the screen so that everyone in the room can see it easily. However, if you start the process without a plan, it can easily turn into a disaster. From punching unnecessary holes in your walls to having your TV fall down while you are watching it, to find the best TV wall mount, for your set up, there are some things you need to consider. Where you put your TV takes some careful consideration. Do you want to hang your TV above the fireplace? If you do, keep in mind you may need a cooling fan for your TV depending on the type of TV wall mount you choose. On one hand, if it stays above the mantel and never moves the mantel will act as a shield from rising heat. On the other hand, in a situation where you have a full-motion mount with vertical movement that puts the TV right in front of the fireplace, a cooling fan is something you are going to need if you don't want to damage your TV and sound bar. Additionally, the type of material used to build the wall you are mounting your TV on is yet another important consideration. For normal walls, you will need one type of TV mount, and for harder surfaces like cement, brick, etc. you will need a specialized type of TV wall mount. These low-profile TV mounts attach nearly flush to the wall to maximize the sleek, thin lines of today's TVs. When your TV needs to be positioned close to the wall and at a fixed height, this type of TV wall mount will be more suitable. They are also a good choice when you want your view to be at eye level, directly in front of your seating area. They are best used in areas where you have total control over the lighting, to avoid glare on the TV screen. If you tend to stay in one place and rarely move around, this is the suggested type of wall mount. These TV mounts tilt up or down for better viewing from a couch, bed or floor. They are recommended when reflections from windows or lighting interfere with TV viewing or when multiple viewing angles are desired. They allow vertical tilting so it can be mounted higher and still point down to provide excellent visibility. The amount of tilt varies by model, but they can typically tilt between 5º and 15º at the touch of a finger. These TV mounts extend, retract, tilt, and swivel in all directions, so they are often the best choice for most homes. They are recommended when multiple viewing positions are desired or when a wall corner, room shape or window location makes it difficult to properly situate a TV. Full motion TV wall mounts (also called articulating mounts) are the most versatile mounts on the market. Nothing will ruin the appearance of your wall mounted TV quicker than loose wires hanging down! While some mounts offer channels in the body where the wires can be run neatly, others offer clips on the outside of the frame to hold the wires in place. In both cases, your wires and cables are not truly hidden. In this case, it's best to get your TV professionally installed. A mess of cables hanging from your TV can easily ruin the sleek look of a wall mounted TV. And, even if you don't plug a single device into your television, you'll still need to deal with an ugly cord trailing down your wall to the electrical socket. With all of this in mind, we offer some suggestions on the best TV wall mount for any set up. While this is the most basic type of TV wall mount, it allows the TV to be placed as close to the wall as possible without sticking out into the room. This can make the most out of the thin depth of your TV. Strong's Razor Mount Fixed Series, is the perfect mount for today's ultra-thin TVs, these low-profile mounts sit just .4" off the wall, offering a clean, finished look without the bulk. Featuring LokTight™ tabs to ensure TVs stay in place and an adjustable safety release ring for easily adding new devices; the Razor Fixed series was designed with both safety and aesthetics in mind. This TV wall mount is similar to the low profile wall bracket except it allows the screen to tilt up or down while attached to the wall. Featuring simple fingertip adjustments, the Razor Tilt Series offers the perfect amount of tilt for the best viewing angle every time, and sit less than 1" off the wall. Adjustable from 5 to 15 degrees with locking screws to hold the TV in place, these mounts also offer home position latching, locking the panel into place against the wall when needed. LokTight™ tabs provide extra security while the adjustable safety release ring offers easy access to the TV connections. Articulating TV wall mounts allow a greater degree of flexibility when it comes to changing the position of your TV screen. The best articulating mounts will allow a wide range of motion. For the ultimate in viewing versatility, the Razor Articulating series offer a low profile solution at a mere 1.6" off the wall, extending out up to 25.5", and swiveling capabilities up to 180 degrees. Curved cast-aluminum arms are lightweight and easily maneuverable, making viewing adjustments smooth and fluid. With both single and dual arm options for larger displays, these Razor Articulating mounts provide the perfect TV placement every time. For those who have fireplaces, getting the TV to a lower position, at the ideal height and level with your eyes can be challenging. While specific scenarios call for mounting a TV above the fireplace such as having little to no wall space to hang it anywhere else. Other scenarios that call for mounting a TV above the fireplace are location. Everyday, more and more people are unifying the focus of their living rooms, and hanging their TVs over the fireplace. Rooms orient better and spaces flow better, making the home look and feel better. Regardless of the scenario, there is a simple solution for anyone who wants to hang their TV above the fireplace. Indoors, or above your outdoor fireplace we offer you some insight on fireplace TV wall mounting solutions that give you the perfect viewing angle, all the time. You're here because your home entertainment greatly matters to you. MantelMount not only offers tilt and swivel, but also allows you to easily pull the TV down off the wall and position it at eye level. And you can just as easily push it right back up. That's no small feat, but it's everything in addition to the full range motion that makes MantelMount a premium solution like no other. MantelMount is an entirely re-imagined, fully optimized home entertainment experience. MantelMounts patented construction combines high-quality automotive pistons with lightweight alloys and state-of-the-art counterbalance technology, allowing virtually anyone to easily pull a large flat screen TV down off the wall, suspend it at eye level in front of the fireplace, and swivel it left or right. MantelMount has triple the amount of performance and safety features than your standard TV wall mount. When you have Shultz Audio Video install a MantelMount, it is not just another TV wall mount… It's a new room, something to WOW your guests with. Virtually no other solutions are available in the marketplace that address the concerns of an above-the-fireplace flat screen television to provide eye-level viewing and glare reduction while also hiding all the hardware associated with your flat screen television. Ideal for anyone who can easily reach the handle to pull the unit down and angle it towards a seating area for the perfect view. Let Shultz Audio Video do a custom TV wall mount for you. Whether it is above the fireplace or level with the wall we have the right solutions for every room. Need help seamlessly blending your home audio and video. Shultz Audio Video will build and install a seamlessly blended Whole Home Audio andVideo System system using the highest quality products on the market! We have the best TV wall mounting solutions to fit your lifestyle and your budget. Technology can make life simple. Shultz Audio Video delivers TV Wall Mounting solutions for every lifestyle, and budget. Bring life to your home entertainment today! As a provider of TV Wall Mount Installation Services in San Diego, Shultz Audio Video brings high value to each of our clients enabling them make their home entertainment dreams come to life. At Shultz Audio Video, our values drive who we are and what we do. We pride ourselves on building one-to-one relationships with each of our clients. We are passionate about providing the very best whole home audio, home theater, security, and home automation solutions on the market. At Shultz Audio Video, we think that everyone should enjoy the latest in home media and entertainment technology. Our promise to you, to provide you with solutions that fit your needs as well as you budget, deliver the solutions that bring your ideas to life, and provide you with a level of service that makes you feel important because the truth is… you are! Our team of San Diego Audio Video, Whole House Audio, Home Automation, and Home Security Experts can help you bring your entertainment and home control dreams to life. Shultz Audio Video we offer total home solutions and home entertainment systems designed for the way you live. Call us today at (760) 505-7461 we have TV wall mounting solutions for every set up and every budget. Make sure to ask about our TV wall mounting specials.
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The Springfield Falcons, proud members of the American Hockey League, announced today that the Edmonton Oilers have named Kelly Buchberger as head coach of the Falcons. Buchberger replaces Geoff Ward, who resigned his post as head coach of the Falcons to accept the role of an assistant coach with the Boston Bruins on Wednesday. This will be the first head coaching position for Buchberger, a veteran of 18 National Hockey League seasons, including 13 seasons with the Oilers. He previously served as an assistant coach to Ward with the AHL's Edmonton Road Runners in 2004-05. The 40-year-old native of Langenburg, Sask., is very familiar with many of the players he will be coaching in Springfield in the upcoming season, having worked with Edmonton's young prospects in the professional ranks as well as junior and college players in his role as the Oilers' development coach during the 2006-07 season. Buchberger will team with new assistant coach Jeff Truitt to guide the Falcons in their first season as the top development club for the Oilers. During his 18 NHL seasons, Buchberger played 1,182 regular-season games in a career that began during the 1987 Stanley Cup Playoffs with the Oilers and concluded in 2003-04 with the Pittsburgh Penguins. He scored 309 points with 105 goals and 204 assists, while registering 2,297 penalty minutes with Edmonton, Atlanta, Los Angeles, Phoenix and Pittsburgh. He added 25 points (10g, 15a) with 129 penalty minutes in 97 playoff games, and was a member of the Oilers' Stanley Cup championship teams in 1987 and 1990. After making his NHL debut with the Oilers during the first three games of the 1987 Stanley Cup Final vs. Philadelphia, Buchberger would go on to play 795 regular-season games in Edmonton before being claimed by the Atlanta Thrashers in the NHL expansion draft in 1999. He ranks 15th on the Oilers' all-time scoring list with 240 points and is the team's career leader in penalty minutes with 1,747. Buchberger was named the Oilers ninth captain in 1995-96 and served in that capacity for four seasons. Buchberger spent his two professional seasons as a player with the AHL's Nova Scotia Oilers, recording 33 goals and 43 assists for 76 points, along with 463 penalty minutes, in 119 games.
7 Industrial Way Suite 6A Our Web Portfolio Website Design Process Magento eCommerce Take Control of Your Website One Page at a Time. It's Easier Than You Think. What are Content Management Systems? A content management system (CMS) is a software system that allows website administrators to create, manage, store and deploy content on Web pages from a central interface. It also allows website designers to code the websites page layouts in such a way that content can be dynamically served to your website visitors, while providing them with a consistent user experience. There are hundreds of CMS systems in use today but only a few stand out. The most successful CMS systems in the world are free and are supported by communities of developers, programmers and users world-wide. This is extremely important when selecting a CMS for your website development project. Like any software, it needs to be updated to ensure security and bugs are fixed quickly and that it has a robust support network. At DCG we primarily use 3 content management systems based on our clients needs. WordPress, Magento and Django CMS. Each has their strengths and their weaknesses. Our goal is to develop your website on the right CMS. WordPress is a free and open source CMS and is, by far, the most popular CMS in use on the Web, with more than 60 million websites worldwide. Even the top website development companies in the world built their own website using the WordPress CMS platform. With that many users, there isn't much WordPress can't do for your website. It is supported by a vast community of developers, programmers and users and if you do experience a technical issue, likely someone has already solved it. Where WordPress fails, Magento excels. Magento is a feature-rich eCommerce platform that gives online merchants complete control over the functionality of their online store. Magento's Search Engine Optimization, Catalog Management, powerful marketing tools and Custom Modules give merchants the ability to create websites that provide the ultimate shopping experience for their customers. Django CMS Our developers keep screaming over Django CMS and how it is the greatest CMS platform ever. So, we took a look. Let's be honest here, sorry Dev Team, Django CMS is not for everyone. But, when it comes to web applications and custom programming solutions, there is no rival. Django CMS is a developers dream CMS. There is no limit to what can be done with Django CMS. We will be keeping an eye on this one. Ready to start a project or want to know more about our website design services? Let's start a conversation and get to know a little more about you. It only takes a minute and could be the foundation to a great relationship. Copyright © 2023 Discovery Communications Group. All Rights Reserved Privacy Policy Copyright © 2023 Discovery Communications Group. All Rights Reserved Privacy Policy | Sitemap Website Design by CleverLight
Mom and pop investors set to drive 'the last phase of the bull market' Published Wed, Dec 6 2017 2:19 PM EST Updated Wed, Dec 6 2017 5:16 PM EST Jeff Cox@JeffCoxCNBCcom Retail participation is considered a classic late-stage sign of a market rally, and money has been coming in from retail buyers and foreign investors, according to a UBS strategist. Exchange-traded funds that focus on stocks have taken in nearly $300 billion in 2017, setting a record. UBS remains bullish on the market in the near term, in fact projecting stocks could rise 25 percent in 2018 under the right circumstances. Increased commitment from mom and pop investors has some Wall Street market pros wondering whether the bull market is showing its age. Retail participation is considered a classic late-stage sign of a market rally — the capitulation of the last bears is generally indicative that there's not much money left to be put to stocks and that it's probably a good time to get out. UBS strategist Keith Parker is looking both at retail buyers and foreign investors as a gauge to how close the bull run is coming to an end. Parker sees the two groups as "driving the last phase of the bull market," which could entail another significant lift for share prices, providing Congress passes tax reform. "In a world flush with liquidity but with less trading liquidity, positioning and flows have and will matter more, particularly around key catalysts like a tax cut," Parker said in a note to clients. "The improvement in US economic data the last 3 months supports the ~7% rally on its own, suggesting positioning is not excessive and a tax cut is also not fully priced." Increases in household and foreign money often has coincided with the risk in markets, staying low in the early phases and peaking at the end. "Historically, we believe that retail and foreign buyers are typically the marginal buyer during the last phases of a bull market," Parker added. "Indeed, we see that US households have been increasing their ownership of US equities (ex (mutual funds), ETFs, pensions), which has happened at the end of prior cycles." Parker points out that in Asia there is some $40 trillion in sideline cash, far above the level in the U.S. Signs that the money is being directed to the U.S. market would indicate that a longer-term top could be setting in. UBS retains a pretty optimistic view on the market, at least for the year ahead. In fact, the firm said that in a best-case scenario that includes passage of tax reform and the earnings benefits it should bring, the could climb to 3,300 by the end of 2018. That would translate to a 25 percent gain from the index's current level. In some ways, though, it seems like retail investors are just getting in on the action, after years of sitting out the nearly 300 percent surge in the S&P 500 since March 2009. For instance, exchange-traded funds that focus on stocks have taken in nearly $300 billion in 2017, more money than all of the $3.4 trillion industry has seen in all asset classes for any given year, according to State Street Global Advisors. ETFs long have been an instrument for professional traders, but ownership has shifted recently to where nearly half the funds are owned by retail investors. Yet there seems to be room to run. Sentiment has been improving but still in check. The American Association of Individual Investors' most recent survey showed bullishness at 35.9 percent against 2.6 percent for bears. The survey asks investors where they think the market is heading in the next six months; optimism was 2.4 points below its historical average, while pessimism was 1.1 points above trend. "While the continued rise of the major U.S. stock indexes into record territory is encouraging to some individual investors, many others have previously expressed concerns about the possibility of a pullback or a more severe drop occurring," Charles Rotblutt, AAII Journal editor, said in a statement. "Tax reform could also be playing a role." Professional investors, meanwhile, are much more bullish. The Investors Intelligence survey this week showed bulls at 64.2 percent against 15.1 percent for the bears. The bullish level, and the spread between the two camps, is near the Black Monday level in 1987. Such high levels of optimism often are contrarian signs for the II survey. WATCH: A Bank of America Merrill Lynch strategist believes the rally is getting winded. Expect the market rally to stall: BofA strategist
HomeCelebrityTV Shows Iyanla Vanzant's 'Fix My Life' Teaser — 3 Generations of LisaRaye McCoy's Family Break Down By Christell Fatima M. Tudtud Actress LisaRaye McCoy, her mother, and daughter had an intense argument in a teaser released for an upcoming episode of Iyanla Vanzant's show "Iyanla: Fix My Life," which airs in December. Family drama erupted at the dining table between LisaRaye McCoy, her mother Katie McCoy, and daughter Kai Morae Pace as they voiced out their dismay with one another. The intense scene was filmed for an upcoming episode of Iyanla Vanzant's show, "Iyanla: Fix My Life." The teaser, which shows the family argument, was posted on the YouTube channel of The Oprah Winfrey Network (OWN) on November 24, 2020. LisaRaye McCoy attends the premiere of Columbia Pictures' "Bad Boys For Life" at TCL Chinese Theatre on January 14, 2020 in Hollywood, California. I Photo: Getty Images HURLING INSULTS In the clip, the three generations of the family are seen airing out their frustrations with one another. As they throw insults at each another, LisaRaye sarcastically asks her mother: "What do I do about it now mama? Can I buy you?" Katie retorts that LisaRaye does not have enough money to buy her. The actress later opens up to Iyanla about her ill feelings towards her mother, saying she never wants to be like her. DEAP-SEATED ISSUES The three women clearly have some deep-seated issues in their family that they have yet to resolve. Iyanla also points out to LisaRaye that her daughter is broken. The mother-daughter relationship didn't seem to be this problematic a few years back. In 2016, the actress threw a baby shower for her daughter, who was pregnant at the time with LisaRaye's first grandchild, in Los Angeles. Prior to her first marriage, LisaRaye welcomed her only daughter, Kai Morae Pace, in 1989. A CHALLENGING PERSONAL LIFE The family tension is not only between the three women. In September, LisaRaye also had a heated verbal exchange with her half-sister, Da Brat, on the show "Cocktails with Queens." Lisa Raye, who has been active in the entertainment industry since 1995, has had a challenging personal life. She had two failed marriages. In 1992, the actress married her first husband, football star Tony Derrick Martin. Their short-lived marriage ended in divorce in 1994. SUCCESS AMID FAILED MARRIAGES Prior to her first marriage, LisaRaye welcomed her only daughter, Kai Morae Pace, in 1989. She shares Kai with motivational speaker and businessman Kenji Pace. She took a second chance at marriage with Michael Misick, whom she married in 2006. Misick was the Premier of Turks and Caicos Islands when they married, making LisaRaye the First Lady. Their marriage, however, eventually fell apart, and they divorced in 2008. Born and raised in Chicago, Illinois, LisaRaye is the daughter of Katie, a professional model, and the late businessman David Ray McCoy. Roseanne Barr Is a Doting Mom & Grandma to Her 5 Look-Alike Kids & 6 Grandchildren Michael Caine Saw His 'Extraordinary' 'Indian Wife' of 48 Years in a Commercial & Was Eager to Find Her Jaclyn Smith Was Married to Bigamist & Shared 2 Kids with Him —Meet Her Grown-up Children & Granddaughters Apart from being an actress, she has also ventured into the modeling and fashion business. As an actress, LisaRaye both appeared in films and television shows. Her most remarkable shows include "All of Us" and "Single Ladies." In the field of business, LisaRaye sank her teeth into the fashion industry. She launched her own lingerie line in 2005 and launched her line of jeans in 2011. Penny Marshall Gave Birth at 19 - Her Husband Wanted a Baby Boy While Her Mother Hid the Child's Real Age Sidney Poitier Promised to Leave His Wife for Diahann Carroll ⁠— He Rejected Her Daughter & Changed His Mind Naomi Judd's Heart Was 'Ripped Out and Stomped on by Men' ⁠— Inside Her Marriages Dean McDermott Refused to Adopt Daughter & Left His Family for Then-Mistress Tori Spelling Meet Lisa Whelchel's Kids with Her Pastor Ex to Whom She Thought She 'Would Be Married Forever' Mariska Hargitay Has 'Perfect' Family with 'Law & Order' Co-star & Kids Who Are Her 'Teachers' John Wayne Knew His 'Marriage Was Over' When He Fathered 4th Baby & His Wife Asked Priest for Help Melanie Griffith & Antonio Banderas' Daughter Wanted to Drop Mom's Last Name — She Removed It Legally Brooke Shields 'Was About Ready' to Stay Childless After Years of Tries - Today She Is a Mother of 2 Robert Wagner's Wife of 32 Years Felt Jealous of His Ex Natalie Wood — His Longest Marriage Debra Winger Still Saves White Dress from 1st Wedding as It Felt 'Electrifying' Wearing It for Her 2nd Husband Shannon Sharpe's Kids Make Him a Proud Father - Facts about Them
Elton John and Arsène Wenger in conversation Me/My Life in Red and White In his first and only official autobiography, music icon Elton John reveals the truth about his extraordinary life. Following on from the hugely successful and critically acclaimed epic musical fantasy Rocketman comes Me a joyously funny, honest and moving story of one of the world's most irrepressible and flamboyant musical geniuses. And of course there is also Elton's passion for football, expressed not least by his decades-long association with Watford FC including, at various times, owning the club, being its chairman and president. The long-awaited autobiography from one of the most influential figures in world football. Arsène Wenger shares his experience of winning multiple Premier League titles, a record number of FA Cups, and how he masterminded Arsenal's historic 'Invincibles' season of 2003-2004 and 49-match unbeaten run. He reflects on a career which changed the game in England for ever, popularising an attacking approach and changing attitudes towards nutrition, fitness and coaching methods – and towards foreign managers. Join us for this unique experience and the final Festival event before the whistle blows on our 21st Winter Weekend. Chaired by Dylan Jones. Me: Elton John Official Autobiography Event 18 Benjamin Zephaniah Saturday 28 November 2020, 10am – 10.30am GMT Event 20 Susie Dent talks to Stephen Fry Saturday 28 November 2020, 1pm – 1.45pm GMT
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Eduo `; // Append message element to the results list list.prepend(message); } }, noResults: true, }, resultItem: { highlight: true }, events: { input: { selection: (event) => { const selection = event.detail.selection.value; autoCompleteJS.input.value = selection; } } } }); autoCompleteJS.input.addEventListener("selection", function (event) { const feedback = event.detail; //autoCompleteJS.input.blur(); // Prepare User's Selected Value //const selection = feedback.selection.value[feedback.selection.key]; //alert(feedback.selection.value.uri); window.location.href = '/' + feedback.selection.value.uri; // Render selected choice to selection div //document.querySelector(".selection").innerHTML = selection; // Replace Input value with the selected value //autoCompleteJS.input.value = selection; // Console log autoComplete data feedback console.log(feedback); }); Sally McNeil Charles Cullen Mehmet Oz Yolanda Saldívar 20th-century English male actors Tom Sturridge Paddy Considine Ralph Fiennes 21st-century English male actors Alumni of New College, Oxford Lucy Worsley Sally Phillips Max Mallowan Charithra Chandran Gyles Brandreth John Grigg (writer) Angus Deayton Rachel Reeves Julian Ovenden Joanna Kuenssberg Dennis Potter Gina Raimondo Marlo Thomas Best Actor BAFTA Award winners Best Musical or Comedy Actor Golden Globe (film) winners César Honorary Award recipients English film producers English male film actors Michael Crawford English male television actors Tom Hopper English male voice actors English people of Scottish descent Charles III Adam Walker (rugby league) Anne, Princess Royal People associated with the News International phone hacking scandal James Murdoch Wendi Deng Murdoch Louise Mensch Rebekah Brooks Tom Watson (Labour politician) Sara Payne Andy Coulson Neville Thurlbeck Paul McMullan (journalist) Paul Stephenson (police officer) Peter Clarke (police officer) Stuart Kuttner Sue Akers Tom Crone Tom Mockridge Andy Hayman Benedict Rattigan Brian Leveson People educated at Latymer Upper School Ophelia Lovibond Heston Blumenthal Toby Regbo Sean Teale Mel Smith Allegra Stratton Simon Kunz Calam Lynch Grace Chatto Rufus Jones (actor) Keith Vaz Louis Hayward Ajahn Brahm Andy Holmes Chris Thomas (record producer) People from Chiswick Ty Tennant Kim Wilde Fella Edmonds Kevin McNally James Dreyfus Mary Macleod Laura Howard People from Hammersmith Lashana Lynch Miguel Sapochnik Jacob Rees-Mogg Volpi Cup for Best Actor winners Birth HammersmithChildren 3Actor Watch as story Save Screen persona Hugh John Mungo Grant (born 9 September 1960) is an English actor. His awards include a British Academy Film Award, a Golden Globe Award, Volpi Cup, and an Honorary César. +more , his films had grossed a total of nearly US$3 billion worldwide from 29 theatrical releases. He first received attention for his performances in costume dramas, including the Merchant-Ivory films Maurice (1987), for which he received the Volpi Cup, and The Remains of the Day (1993), as well as Sense and Sensibility (1995) and Restoration (1995). Grant achieved international success after appearing in Richard Curtis's romantic comedy film Four Weddings and a Funeral (1994), whereupon he received the Golden Globe Award for Best Actor - Motion Picture Musical or Comedy and the British Academy Film Award for Best Actor. +more He then became widely known as a movie star, establishing himself as a charming, vulnerable, witty romantic lead with satirical comic talent. He starred in the romantic comedies Notting Hill (1999), Bridget Jones's Diary (2001), About a Boy (2002), Two Weeks Notice (2002), Love Actually (2003), and Music and Lyrics (2007). Grant began to take against-type parts, starting with multiple roles in The Wachowskis' epic science fiction drama film Cloud Atlas (2012). He received critical acclaim for his portrayals of +more_Clair_Bayfield'>St. Clair Bayfield in Stephen Frears' Florence Foster Jenkins (2016), alongside Meryl Streep, for which he received a British Academy Film Award and a Golden Globe Award, and Screen Actors Guild Award nominations. The next year, he starred in the family comedy Paddington 2 (2017) as the antagonist, Phoenix Buchanan, for which he received a British Academy Film Award for Best Supporting Actor nomination. In 2018, he portrayed Jeremy Thorpe in the BBC miniseries A Very English Scandal, earning a Primetime Emmy Award for Best Actor in a Limited Series nomination. He also starred in the action films The Man from U. N. C. L. E. (2015) and The Gentlemen (2019). Most recently, he starred in the HBO thriller miniseries The Undoing, (2020) opposite Nicole Kidman, for which he received his second Primetime Emmy Award nomination. Grant is known as a meticulous performer who approaches his roles like a character actor, working hard to make his acting appear spontaneous. Hallmarks of his comic skills include a nonchalant touch of sarcasm and characteristic physical mannerisms. +more He has been outspoken about his antipathy towards the profession of acting, his disdain towards the culture of celebrity, and his hostility towards the media. He emerged as a prominent critic of the conduct of Rupert Murdoch's News Corporation during the News International phone hacking scandal. In a career spanning more than 35 years, Grant has repeatedly claimed that acting was not his true calling, but rather a career that developed by happenstance. However, in 2020, after moving on to more character roles, he has stated that he "enjoys acting now". Join Group About Hugh Grant +more images (4) Did Julia Roberts and Hugh Grant get along? Does Hugh Grant have any biological children? Where is Hugh Grant now? Is Hugh Grant a Millionaire? Grant was born on 9 September 1960 in White City, London, the second son of Fynvola Susan MacLean (née Wickham) and Captain James Murray Grant. His grandfather, Colonel James Murray Grant, DSO, was decorated for bravery and leadership at Saint-Valery-en-Caux during World War II. +more Genealogist Antony Adolph has described Grant's family history as "a colourful Anglo-Scottish tapestry of warriors, empire-builders, and aristocracy. " His ancestors include Sir Walter Raleigh; William Drummond, 4th Viscount Strathallan; James Stewart; John Murray, 1st Marquess of Atholl; Heneage Finch, 1st Earl of Nottingham; Sir Evan Nepean; and a sister of Prime Minister Spencer Perceval. Grant's father was an officer in the Seaforth Highlanders for eight years in Malaya and Germany. He ran a carpet firm, and pursued hobbies such as golf and watercolor painting; he raised his family in Chiswick, West London, and the Grants lived next to Arlington Park Mansions on Sutton Lane. +more In September 2006, a collection of Capt. Grant's paintings was hosted by the John Martin Gallery in a charity exhibition, organised by his son, called "James Grant: 30 Years of Watercolours". His mother worked as a schoolteacher and taught Latin, French, and music for more than 30 years in the state schools of West London. She died at the age of 67 of pancreatic cancer. On Inside the Actors Studio in 2002, Grant credited his mother with "any acting genes that [he] might have". Both his parents were children of military families, but despite his parents' backgrounds, he has stated that his family was not always affluent while growing up. +more He spent many of his childhood summers shooting and fishing with his grandfather in Scotland. Grant has an older brother, James "Jamie" Grant, a New York-based investment banker. Grant started his education at Hogarth Primary School in Chiswick, then moved to St Peter's Primary School in Hammersmith, followed by Wetherby School, an independent preparatory school in Notting Hill. From 1969 to 1978, he attended Latymer Upper School in Hammersmith, at the time a direct grant grammar school. +more He was educated on a scholarship and played 1st XV rugby, cricket, and football. He also represented Latymer Upper on the quiz show Top of the Form, an academic competition between two teams of four secondary school students each. In 1979, he won the Galsworthy scholarship to New College, Oxford. He studied English literature and graduated with second-class honours. +more Viewing acting as nothing more than a creative outlet, he joined the Oxford University Dramatic Society and was Fabian in a production of Twelfth Night. He also starred in his first film, Privileged (1982), produced by the Oxford University Film Foundation. He received an offer from the Courtauld Institute of Art, University of London, to pursue a PhD in art history, but decided not to take the offer because he failed to secure a grant. 1982-1986: First film; stage and comedy work After making his debut in the Oxford-financed film Privileged (1982), Grant dabbled in a variety of jobs, such as working as an assistant groundsman at +more'>Fulham Football Club, tutoring, writing comedy sketches for TV shows and working for Talkback Productions to write and produce radio commercials for products such as Mighty White bread and Red Stripe lager. At a screening of Privileged at BAFTA in London, he was approached by a talent agent offering to represent him. Still intending to begin his MPhil at the Courtauld Institute, Grant declined, but then later reconsidered, thinking that acting for a year would be a good way to save some money for his studies. Soon afterwards he was offered a supporting role in The Bounty (1984) starring Mel Gibson and Anthony Hopkins, but was prevented from playing the role because he didn't yet have an Equity card, which could only be earned through acting in regional theatre. To obtain his Equity card, he joined the Nottingham Playhouse and lived for a year at Park Terrace in The Park Estate in Nottingham. +more Richard Digby Day directed him in small roles at the Nottingham Playhouse in Lady Windermere's Fan, an avant-garde production of Hamlet and Coriolanus. Bored with small acting parts, Grant created a sketch-comedy group called The Jockeys of Norfolk, a name taken from Shakespeare's Richard III, with friends Chris Lang and Andy Taylor. The group toured London's pub comedy circuit with stops at The George IV in Chiswick, Canal Cafe Theatre in Little Venice and The King's Head in Islington. +more The Jockeys of Norfolk proved a hit at the 1985 Edinburgh Festival Fringe after their sketch on the Nativity, told as an Ealing comedy, gained them a spot on Russell Harty's BBC2 TV show Harty Goes to. In 1986 he played Eric Birling in a production of An Inspector Calls at the Royal Exchange Theatre in Manchester, directed by Richard Wilson, giving a performance that Grevel Lindop, writing in the Times Literary Supplement, described as "outstanding". 1985-1993: Maurice and other projects In 1985 and 1986, Grant had minor roles in eight television productions, including TV films, historical miniseries and single episodes of series. His first leading film role came in Merchant-Ivory's Edwardian drama film Maurice (1987), adapted from +more_M. _Forster'>E. M. Forster's novel. He and co-star James Wilby shared the Volpi Cup for Best Actor at the Venice Film Festival for their portrayals of lovers Clive Durham and Maurice Hall, respectively. During the late 1980s and early 1990s, he balanced small roles on television with film work, which included playing Hugh Cholmondeley, 3rd Baron Delamere in the BAFTA Award-nominated White Mischief (1987) and a supporting role in The Dawning (1988) opposite Anthony Hopkins and Jean Simmons. In 1988 he had a leading role in Ken Russell's horror film, The Lair of the White Worm. He was Lord Byron in a Goya Award-winning Spanish production called Remando al viento (1988) and portrayed legendary champagne merchant Charles Heidsieck in the television film Champagne Charlie (1989). +more In 1990 he had a small role in the sport/crime drama The Big Man, opposite Liam Neeson, in which Grant assumed a Scottish accent; the film explores the life of a Scottish miner (Neeson) who becomes unemployed during a union strike. In 1991 he played Julie Andrews' gay son in the ABC made-for-television film Our Sons. In 1991 he also starred as Frederic Chopin in Impromptu, opposite Judy Davis as his lover George Sand. In 1992 he appeared in Roman Polanski's film Bitter Moon, portraying a fastidious and proper British tourist who is married but finds himself enticed by the sexual hedonism of a seductive French woman and her embittered, paraplegic American husband. The film was called an "anti-romantic opus of sexual obsession and cruelty" by The Washington Post. +more In 1993 he had a supporting role in the Merchant-Ivory drama The Remains of the Day. Grant later jokingly called many of the productions of his early career "Europuddings, where you would have a French script, a Spanish director and English actors. The script would usually be written by a foreigner, badly translated into English. +more And then they'd get English actors in, because they thought that was the way to sell it to America. ". 1993-1999: Four Weddings and a Funeral and stardom At 32, Grant claimed to be on the brink of giving up the acting profession but was surprised by the script of Four Weddings and a Funeral (1994). "If you read as many bad scripts as I did, you'd know how grateful you are when you come across one where the guy actually is funny," he later recalled. +more Released in 1994 with Grant as the protagonist, Four Weddings and a Funeral became the highest-grossing British film to date with a worldwide box office in excess of $244 million, making him an overnight international star. His entry in The Trouble with Men: Masculinities in European and Hollywood Cinema states:. [wiki_quote=7b6de71b] The film was nominated for two Academy Awards and, among numerous awards won by its cast and crew, it earned Grant a Golden Globe Award for Best Actor - Motion Picture Musical or Comedy and a BAFTA Award for Best Actor in a Leading Role. It also temporarily typecast him as the lead character, Charles, a bohemian and debonair bachelor. +more Grant saw it as an inside joke that the star, due to the parts he played, was assumed to have the personality of the screenwriter (Richard Curtis), who is known for writing about himself and his own life. Grant later expressed:. [wiki_quote=4af6b558] In July 1994, he signed a two-year production deal with Castle Rock Entertainment and, by October, he became founder and director of the UK-based Simian Films Limited. He appointed his then-girlfriend, Elizabeth Hurley, as the head of development to look for prospective projects. +more Simian Films produced two Grant vehicles in the 1990s and lost a bid to produce About a Boy to Robert De Niro's TriBeCa Productions. The company closed its US office in 2002 and Grant resigned as director in December 2005. Before the release of Four Weddings and a Funeral, Grant had reunited with its director Mike Newell for the tragicomedy An Awfully Big Adventure (1995), which was labelled a "determinedly off-beat film" by The New York Times. He portrayed the supercilious director of a repertory company in post-World War II Liverpool. +more Critic Roger Ebert wrote, "It shows that he has range as an actor" but the San Francisco Chronicle disapproved on grounds that the film "plays like a vanity production for Grant". Janet Maslin, praising Grant as "superb" and "a dashing cad under any circumstances", commented, "For him this film represents the road not taken. Made before Four Weddings and a Funeral was released, it captures Mr. Grant as the clever, versatile character actor he was then becoming, rather than the international dreamboat he is today. " His next role was as a cartographer in 1917 Wales in The Englishman Who Went Up a Hill But Came Down a Mountain (1995). Grant's first studio-financed Hollywood project was opposite Julianne Moore in Chris Columbus's comedy Nine Months (1995). Though a hit at the box office, it was almost universally panned by critics. +more The Washington Post called it a "grotesquely pandering caper" and singled out Grant's performance, as a child psychiatrist reacting unfavourably to his girlfriend's unexpected pregnancy, for his "insufferable muggings". Grant himself has been highly critical of his performance in Nine Months, stating in a 2016 interview: [wiki_quote=e708b768]. Next in 1995, he starred as Emma Thompson's suitor in her Academy Award-winning adaptation of Jane Austen's Sense and Sensibility, directed by Ang Lee. In 1995 he also performed in Restoration; Lisa Schwarzbaum wrote that Grant is "having a fine and liberating time playing a supercilious court portrait painter", and Kevin Thomas of Los Angeles Times said he has "some delicious moments" in the film. He made his debut as a film producer with the 1996 thriller Extreme Measures. Roger Ebert and Gene Siskel each gave the film three out of four stars, with Siskel writing "Hugh Grant's work in Extreme Measures is a refreshing standout. +more". After a three-year hiatus, in 1999 he paired with Julia Roberts in Notting Hill, which was written by Richard Curtis and produced by much of the same team that was responsible for Four Weddings and a Funeral. This new Working Title production displaced Four Weddings and a Funeral as the biggest British hit in the history of cinema, with earnings equalling $363 million worldwide. +more As it became exemplary of modern romantic comedies in mainstream culture, the film was also received well by critics. CNN reviewer Paul Clinton said, "Notting Hill stands alone as another funny and heartwarming story about love against all odds. " Reactions to his Golden Globe-nominated performance were varied, with Salon. com's Stephanie Zacharek criticising that, "Grant's performance stands as an emblem of what's wrong with Notting Hill. What's maddening about Grant is that he just never cuts the crap. He's become one of those actors who's all shambling self-caricature, from his twinkly crow's feet to the time-lapsed half century it takes him to actually get one of his lines out. " The film provided both its stars a chance to satirise the woes of international notoriety, most noted of which was Grant's turn as a faux-journalist who sits through a dull press junket with what The New York Times called "a delightfully funny deadpan". Grant also released his second production output, a fish-out-of-water mob comedy Mickey Blue Eyes, that year. It was dismissed by critics, performed modestly at the box office and garnered its actor-producer mixed reviews for his starring role. +more Roger Ebert thought, "Hugh Grant is wrong for the role [and] strikes one wrong note and then another", whereas Kenneth Turan, writing in the Los Angeles Times, said, "If he'd been on the Titanic, fewer lives would have been lost. If he'd accompanied Robert Scott to the South Pole, the explorer would have lived to be 100. That's how good Hugh Grant is at rescuing doomed ventures. ". 2000-2009: Continued romantic comedy roles While promoting Woody Allen's Small Time Crooks (2000) on NBC's The Today Show in 2000, Grant told host Matt Lauer, "It's my millennium of bastards". Small Time Crooks starred Grant, in the words of film critic Andrew Sarris, as "a petty, petulant, faux-Pygmalion art dealer, David, [who] is one of the sleaziest and most unsympathetic characters Mr. +more Allen has ever created". In a role devoid of his comic attributes, The New York Times wrote: "Mr. Grant deftly imbues his character with exactly a perfect blend of charm and nasty calculation. " In 2000, Grant also joined the supervisory board of IM Internationalmedia AG, the powerful Munich-based film and media company. In 2001, his turn as a charming but womanising book publisher Daniel Cleaver in Bridget Jones's Diary was proclaimed by Variety to be "as sly an overthrow of a star's polished posh - and nice - poster image as any comic turn in memory". The film, adapted from Helen Fielding's novel of the same name, was an international hit, earning $281 million worldwide. +more He was, according to The Washington Post, fitting as "a cruel, manipulative cad, hiding behind the male god's countenance that he knows all too well". In 2002, Grant's "immaculate comic performance" (BBC) as the trust-funded womaniser, Will Freeman, in the film adaptation of Nick Hornby's best-selling novel About a Boy received raves from critics. Almost universally praised, with an Academy Award-nominated screenplay, About a Boy (2002) was determined by The Washington Post to be "that rare romantic comedy that dares to choose messiness over closure, prickly independence over fetishised coupledom, and honesty over typical Hollywood endings". +more Rolling Stone wrote, "The acid comedy of Grant's performance carries the film [and he] gives this pleasing heartbreaker the touch of gravity it needs", while Roger Ebert observed that "the Cary Grant department is understaffed, and Hugh Grant shows here that he is more than a star, he is a resource". Released a day after the blockbuster Star Wars: Episode II - Attack of the Clones, About a Boy was a more modest box office grosser than other successful Grant films, making all of $129 million globally. The film earned Grant his third Golden-Globe nomination, while the London Film Critics Circle named Grant its Best British Actor and GQ honoured him as one of the magazine's men of the year 2002. "His performance can only be described as revelatory", wrote critic Ann Hornaday, adding that "Grant lends the shoals layer upon layer of desire, terror, ambivalence and self-awareness. " The New York Observer concluded: "[The film] gets most of its laughs from the evolved expertise of Hugh Grant in playing characters that audiences enjoy seeing taken down a peg or two as a punishment for philandering and womanising and simply being too handsome for words-and with an English accent besides. In the end, the film comes over as a messy delight, thanks to the skill, generosity and good-sport, punching-bag panache of Mr. Grant's performance. " About a Boy also marked a notable change in his boyish look. Now 41, he had lost weight and also abandoned his trademark floppy hair. Entertainment Weekly's Owen Gleiberman took note of Grant's maturation in his review, saying he looked noticeably older and that it "looked good on him". He added that Grant's "pillowy cheeks are flatter and a bit drawn, and the eyes that used to peer with 'love me' cuteness now betray a shark's casual cunning. Everything about him is leaner and spikier (including his hair, which has been shorn and moussed into a Eurochic bed-head mess), but it's not just his surface that's more virile; the nervousness is gone, too. Hugh Grant has grown up, holding on to his lightness and witty cynicism but losing the stuttering sherry-club mannerisms that were once his signature. In doing so, he has blossomed into the rare actor who can play a silver-tongued sleaze with a hidden inner decency. ". He was paired with Sandra Bullock in Warner Bros. +more's Two Weeks Notice (2002), which made $199 million internationally but received poor reviews. The Village Voice concluded that Grant's creation of a spoiled billionaire fronting a real estate business was "little more than a Britishism machine". Two Weeks Notice was followed by the 2003 ensemble comedy, Love Actually, headlined by Grant as the British Prime Minister. A Christmas release by Working Title Films, the film was promoted as "the ultimate romantic comedy" and accumulated $246 million at the international box office. +more It marked the directorial debut of Richard Curtis, who told The New York Times that Grant adamantly tempered the characterisation of the role to make his character more authoritative and less haplessly charming than earlier Curtis incarnations. Roger Ebert claimed that "Grant has flowered into an absolutely splendid romantic comedian" and has "so much self-confidence that he plays the British prime minister as if he took the role to be a good sport". Film critic Rex Reed, on the contrary, called his performance "an oversexed bachelor spin on Tony Blair" as the star "flirted with himself in the paroxysm of self-love that has become his acting style". In 2004, he reprised his role as Daniel Cleaver for a small part in Bridget Jones: The Edge of Reason, which, like its predecessor, made more than $262 million commercially. Gone from the screen for two years, Grant next re-teamed with Paul Weitz (About a Boy) for the black comedy American Dreamz (2006). Grant starred as the acerbic host of an American Idol-like reality show where, according to Caryn James of The New York Times, "nothing is real . +more except the black hole at the centre of the host's heart, as Mr. Grant takes Mr. Cowell's villainous act to its limit". American Dreamz failed financially but Grant was generously praised. He played his self-aggrandising character, an amalgam of Simon Cowell and Ryan Seacrest, with smarmy self-loathing. The Boston Globe proposed that this "just may be the great comic role that has always eluded Hugh Grant", and critic Carina Chocano said, "He is twice as enjoyable as the preening bad guy as he was as the bumbling good guy. ". In 2007, he starred opposite Drew Barrymore in a parody of pop culture and the music industry called Music and Lyrics. The Associated Press described it as "a weird little hybrid of a romantic comedy that's simultaneously too fluffy and not whimsical enough". +more Though he neither listens to music nor owns any CDs, Grant learned to sing, play the piano, dance (a few mannered steps) and studied the mannerisms of prominent musicians to prepare for his role as a has-been pop singer, based loosely on Andrew Ridgeley, member of 1980s pop duo Wham!. The film, with its revenues totalling $145 million, allowed him to mock disposable pop stardom and fleeting celebrity through its washed-up lead character. According to the San Francisco Chronicle, "Grant strikes precisely the right note with regard to Alex's career: He's too intelligent not to be a little embarrassed, but he's far too brazen to feel anything like shame. ". In 2009, he starred opposite Sarah Jessica Parker in the Marc Lawrence's romantic comedy Did You Hear About the Morgans?, which was a critical failure and box office disappointment. 2012-2015: Mid-career experimentation Grant was featured in the Wachowskis' and Tom Tykwer's epic science fiction film Cloud Atlas in 2012, playing six different dark characters. In the same year, Grant lent his voice to the Aardman stop motion animation The Pirates! In an Adventure with Scientists!. +more He reunited with Lawrence again for a dramedy film The Rewrite (2014), starring opposite Marisa Tomei. The film received mixed-to-positive reviews, while Grant's performance was praised by many critics; director Quentin Tarantino has stated that the film is one of his favourites of the year and called Grant a "perfect leading man". In 2015, he had a supporting role as Alexander Waverly in Guy Ritchie's crime thriller +moreC. L. E. _(film)'>The Man from U. N. C. L. E. ; Entertainment Weekly described his performance as "the only bit of fun" in the film, and Glenn Kenny of Rogerebert. com gave the film a mixed review but stated that "while it can't be said that Hugh Grant saves the movie, his return to prominence in the last half-hour, after a plot-seeding-walk-on earlier in the movie, peps things up considerably". 2016-present: Mature career renaissance In 2016, Grant played St. +more Clair Bayfield, partner of the title character, in the film Florence Foster Jenkins, directed by Stephen Frears and starring Meryl Streep. His performance drew raves from film critics as "career-best" (Screen International), "one of his best performances in years" (Indiewire), "best work of his career" (Variety) where he "goes deeper, darker and riskier" (Rolling Stone). Rafer Guzman of Newsday said "Surely the 55-year-old actor has just sealed his first-ever Oscar nomination. " Carrie Rickey of Yahoo! Movies commented that Grant "deserves the Globe, an Oscar nomination, and the recognition - finally - that he is unique and irreplaceable among modern actors". He was nominated for his first individual Screen Actors Guild Award and also earned nominations for a BAFTA, a Golden Globe, a Critics' Choice Award, a Satellite Award and a European Film Award. Several critics put his work among the best acting performances of the year. Most award pundits predicted Grant would receive his first Academy Award nomination for his performance, but he was not nominated. His next appearance was as Phoenix Buchanan, a villain in the family film Paddington 2, which was a commercial and critical success. The Guardian described his performance as "scene-stealing", while IGN commented "Grant continues to make an astonishing comeback in his career, once again by playing into his expert comedic abilities as Phoenix Buchanan, who dons each of his ridiculous disguises with a kind of egotistical obliviousness that Grant is perfect at pulling off. +more" Grant went on to win London Film Critics' Circle Award for Supporting Actor of the Year and was nominated for a BAFTA Award for Best Actor in a Supporting Role for his performance. Grant's performance was ranked as the 22nd greatest movie performance of the decade by IndieWire in 2019. In 2018, Grant returned to television screens after 25 years, as Jeremy Thorpe in the BBC One miniseries A Very English Scandal, which marked his second collaboration with director Stephen Frears. The miniseries, and in particular Grant, were widely and highly praised. +more Digital Spy's review stated that "There's always been a bit of the devil in Grant's best turns, and in Thorpe, a man with a fully-realised dark side, he's found his richest part in years". The New Statesman wrote, "Hugh Grant is Thorpe, and everything about his performance is exactly so. It's the role of Grant's life, and he performs it even more brilliantly than he did Phoenix Buchanan in Paddington 2. " The Sunday Times stated, "It's become tediously predictable to praise this drama but, as Thorpe, Hugh Grant really has proved he's getting better as he's getting older". The Guardian called him "utterly captivating", and The Boston Globe wrote, "Grant is a revelation". The New Yorker stated, "Hugh Grant gives a brilliant performance as Thorpe, whose arrogance, charm, and profoundly evasive nature he captures with subtlety. A quarter century after Grant established himself as everyone's crush with his romantic-comedy début, in Four Weddings and a Funeral . the actor, who is now in his late fifties, has turned out to have a gift for conveying what happens to an individual when charm curdles into something considerably darker. " For his performance, Grant was nominated for several awards, including the Primetime Emmy Award, Screen Actors Guild Award, Golden Globe Award, British Academy Television Award. In 2019, Grant played another against-type role, in Guy Ritchie's The Gentlemen, his second collaboration with the director following The Man From U. N. +moreC. L. E. Grant plays Fletcher, a seedy and unscrupulous private investigator, which he called "a fun bit of casting" referring to his Hacked Off campaigning. He has stated he based his character on tabloid reporters who "used to be my enemies and now they're my friends". Even though the film received mostly mixed reviews, Grant's performance was praised. Stephen Dalton of The Hollywood Reporter called Grant "a beating comic heart" of the film, adding that "he weighs up every wry line with relish, and Ritchie makes strong use of his deadpan comic talents. " Joe Morgenstern of Wall Street Journal also highly praised his work, writing, "[I]n a word, Mr. Grant is sensational. In two more words, he's absolutely hilarious; it's some of the best work he's done on screen. ". In 2020, Grant starred in HBO miniseries The Undoing, opposite Nicole Kidman and Donald Sutherland. The miniseries was premiered on 25 October 2020 to mixed reviews, though Grant's performance was widely acclaimed. +more Film critic Caryn James said Grant has the "richest part" and added, "He sharply defines Jonathan as a slippery character, and walks the line expertly to keep us off guard. How much should we trust Jonathan? When he starts confessing some secrets, is all or any of it true? With this role and that in the recent A Very English Scandal, Grant has become expert at bringing his charm to darker characters. " Brian Tallerico of RogerEbert. com was less impressed with the series but called Grant's performance as the "series-best". Grant received a Screen Actor Guild Award, Golden Globe Award and Critics' Choice Television Award nomination for his performance. Grant reunited with Guy Ritchie for the action Operation Fortune: Ruse de Guerre alongside Jason Statham and Aubrey Plaza with a released date yet to be announced. He is also set to star in the fantasy adventure film Dungeons & Dragons: Honor Among Thieves and the Jerry Seinfeld comedy film Unfrosted: The Pop-Tart Story. The New York Observer Grant began his career as a character actor but became predominantly a comedy (especially a romantic comedy) actor from his rise to stardom in mid-1990s until the 2010s. He said he moved away from romantic comedies after the failure of Did You Hear About the Morgans? (2009). +more In a 2020 interview with The Sydney Morning Herald, he said: "I got old and ugly and I'm not appropriate for romantic comedy films anymore, which has been a great blessing". Even though his recent credits include political dramas like A Very English Scandal and crime films like The Gentlemen, Grant is still often associated with his Richard Curtis-scripted romantic comedy films. In the British press, it is common to compare young romantic comedy actors to him. [wiki_quote=37171db5] Remarking upon his romantic comedy star era, some film critics, such as Roger Ebert, have defended the limited variety of his performances, while some others have dismissed Grant as a "one-trick pony". Eric Fellner, co-owner of Working Title Films and a longtime collaborator, said, "His range hasn't been fully tested, but each performance is unique. +more" Many of Grant's films of the 1990s followed a similar plot that captured an optimistic bachelor experiencing a series of embarrassing incidents to find true love, often with an American woman. In earlier films, he was adept at plugging into the stereotype of a repressed Englishman for humorous effects, allowing him to gently satirise his characters as he summed them up and played against the type simultaneously. These performances were sometimes deemed excessive, in the words of The Washington Posts Rita Kempley, due to Grant's "comic overreactions-the mugging, the stuttering, the fluttering eyelids". She added: "He's got more tics than Benny Hill. " His penchant for conveying his characters' feelings with mannerisms, rather than direct emotions, has been one of the foremost objections raised against his acting style. Stephen Hunter of The Washington Post once stated that, to be effective as a comic performer, Grant must get "his jiving and shucking under control". Film historian David Thomson opined in The New Biographical Dictionary of Film that the actor equated merely "itchy mannerisms" with screen acting. Grant's screen persona in his films of the 2000s gradually developed into a cynical, self-loathing cad. Claudia Puig of USA Today celebrated this transformation with the observation that finally "gone [were] the self-conscious 'Aren't I adorable' mannerisms that seemed endearing at the start of his film career but have grown cloying in more recent movies". +more According to Carina Chocano, amongst film critics, the two tropes most commonly associated with Grant are that he reinvented his screen persona in Bridget Jones's Diary and About a Boy and dreads the possibility of becoming a parody of himself. Nonetheless, Grant has occasionally acted in dramas. He played a sleazy, snide community theatre director with a penchant for young actors in the drama film An Awfully Big Adventure, which received critical praise, and for "a very quiet, dignified" performance as Frédéric Chopin in James Lapine's biopic film Impromptu. +more In 2012, he played six "incredibly evil" characters in the epic drama film Cloud Atlas, an experience he has talked about positively, saying: [wiki_quote=f60eb36c]. After Cloud Atlas, Grant has never starred in a romantic comedy film with an exception of the dramedy The Rewrite (2014), where "romantic comedy is only a small part of it." Grant has expressed boredom with playing the celebrity in the press and is known in the media for his guarded privacy. On probing of his personal life, he has remained steadfast in "offering a dead bat to any question he feels is not general enough". +more He has described himself as a reluctant actor, has called being a successful actor a mistake and has repeatedly talked of his hope that film stardom would just be "a phase" in his life, lasting no more than ten years. A 2007 Vogue profile referred to him as a man with a "professionally misanthropic mystique". He has expressed distaste for focus groups, market research, and emphasis on opening weekend box-office numbers, saying: "It's so destructive to the filmmaking process. +more What was wrong with the way they used to release films, more slowly, let them build?" The director Mike Newell has said: "There is at least as much of Hugh that is charismatic, intellectual, and whose tongue is maybe too clever for its own good as there is of him that's gorgeous and kind of woolly and flubsy. " Filmmaker Paul Weitz said that Grant is funny and that "he perceives flaws in himself and other people, and then he cares about their humanity nonetheless". British newspapers regularly refer to him as "grumpy". Grant is a self-confessed "committed and passionate" perfectionist on a film set. The American film critic Dave Kehr has written that Grant "is known in the film industry as a meticulous performer who takes his time to prepare a role - someone who works hard to make it look easy - though that isn't a trait he admires in himself". +more He is noted by co-workers for demanding endless takes until he achieves the desired shot according to his own standard. He dropped his agent in 2006, ending a 10-year relationship with CAA. He has proclaimed in interviews that he does not listen to external views on his career: "They've known for years that I have total control. +more I've never taken any advice on anything. ". Libel lawsuits In 1996, Grant won substantial damages from News (UK) Ltd over what his lawyers called a "highly defamatory" article published in January 1995. The company's newspaper, Today, which ceased publication the following November, had falsely claimed that Grant verbally abused a young extra with a "foul-mouthed tongue lashing" on the set of The Englishman Who Went Up a Hill But Came Down a Mountain. On 27 April 2007, he accepted undisclosed damages from Associated Newspapers over claims made about his relationships with his former girlfriends in three separate tabloid articles, which were published in the Daily Mail and The Mail on Sunday on 18, 21 and 24 February. His lawyer stated that all of the articles' "allegations and factual assertions are false". +more Grant said, in a written statement, that he took the action because: "I was tired of the Daily Mail and Mail on Sunday papers publishing almost entirely fictional articles about my private life for their own financial gain. " He went on to take the opportunity to stress, "I'm also hoping that this statement in court might remind people that the so-called 'close friends' or 'close sources' on which these stories claim to be based almost never exist. ". On 27 June 1995, Grant was arrested in Los Angeles, California, in a police vice operation near Sunset Boulevard for receiving oral sex in a public place from Hollywood prostitute Divine Brown. He pleaded no contest and was fined $1,180, placed on two years' summary probation, and was ordered to complete an AIDS education program by Judge +more_Sandoval'>Robert J. Sandoval. The arrest occurred about two weeks before the release of his first major studio film, Nine Months, which he was scheduled to promote on several American television shows. The Tonight Show with Jay Leno had him booked for the same week. +more In the much-watched interview (which saw Leno overtake David Letterman in the ratings), Grant did not make excuses for the incident after Leno asked him, "What the hell were you thinking?" Grant answered, "I think you know in life what's a good thing to do and what's a bad thing, and I did a bad thing. And there you have it. ". On Larry King Live, he declined host Larry King's repeated invitations to probe his psyche, saying that psychoanalysis was "more of an American syndrome" and he himself was "a bit old fashioned". He told the host: "I don't have excuses. +more" CNN reported that "Many are also applauding Grant for his refreshing honesty in a culture that has become fed up with overuse of the word 'abuse,' but Grant did not resort to an excuse. " Radio host Scott Shannon said, "He went ahead and faced the music and handled it with tongue [in] cheek. ". In April 2007, he was arrested on allegations of assault made by paparazzo Ian Whittaker. Grant made no official statement and did not comment on the incident. +more Charges were dropped on 1 June 2007 by the Crown Prosecution Service on the grounds of "insufficient evidence". Phone hacking exposé In April 2011, Grant published an article in the New Statesman titled "The Bugger, Bugged" about a conversation (following an earlier encounter) with Paul McMullan, a former journalist and paparazzo for News of the World. In unguarded comments which were secretly taped by Grant, McMullan alleged that editors at the Daily Mail and News of the World, particularly Andy Coulson, had ordered journalists to engage in illegal phone tapping and had done so with the full knowledge of senior British politicians. +more McMullan also said that every British Prime Minister from Margaret Thatcher onwards had cultivated a close relationship with Rupert Murdoch and his senior executives. He stressed the friendship between David Cameron and Rebekah Brooks (née Wade), agreeing when asked that both of them must have been aware of illegal phone tapping, and asserting that Cameron's inaction could be explained by self-interest: "Cameron is very much in debt to Rebekah Wade for helping him not quite win the election . So that was my submission to parliament - that Cameron's either a liar or an idiot. ". When asked by Grant whether Cameron had encouraged the Metropolitan Police to "drag their feet" on investigating illegal phone tapping by Murdoch's journalists, McMullan agreed this had happened, and stated that police themselves had taken bribes from tabloid journalists: "20 percent of the Met has taken backhanders from tabloid hacks. So why would they want to open up that can of worms?. +more And what's wrong with that, anyway? It doesn't hurt anyone particularly. ". Grant's article attracted considerable interest, due to both the revelatory content of the taped conversation, and the novelty of his "turning the tables" on a tabloid journalist. While the allegations regarding the News of the World continued to receive coverage in the broadsheets and similar media (Grant appeared, for example, on BBC Radio 4) it was only with the revelation that the voicemail of murdered Milly Dowler had been hacked, and evidence for her murder enquiry had been deleted, that the coverage turned from media interest to widespread public (and eventually political) outrage. Grant became something of a spokesman against Murdoch's News Corporation, culminating in his appearance on BBC television's Question Time in July 2011. +more Grant later said: "It's been fascinating to have a little excursion into another world. I really needed that and also to be dealing with real life instead of creating synthetic life, which is what I've been doing for the last 25 years. ". On 5 February 2018, Mirror Group Newspapers apologised for its actions towards Grant and other public figures, calling the affair "morally wrong". This came after Grant accepted a six-figure sum to settle a High Court action. +more He donated the payout to the press campaign group Hacked Off. In 1987, while playing Lord Byron in the Spanish production Remando Al Viento (1988), Grant met actress Elizabeth Hurley, who was cast in a supporting role as Byron's former lover Claire Clairmont. He began dating Hurley during filming and their relationship was subsequently the subject of much media attention. +more While dating Hurley, Grant gained international notoriety for soliciting the services of a prostitute in 1995. They separated in May 2000, but Grant is godfather to Hurley's son Damian, born in 2002. Grant has five children with two women. In September 2011, he had a daughter, Tabitha, with Tinglan Hong, who was sometimes misreported in the press as a receptionist at a Chinese restaurant in London. +more His daughter's Chinese name is Jing Xi (驚喜), meaning "happy surprise". Grant and Hong had a "fleeting affair", according to his publicist. He has said that Hong has been "badly treated" by the media; the press intrusion prevented him from attending the birth of his daughter, with Hong obtaining an injunction to allow him to visit them in peace. In September 2012, Grant had his second child, a son, with Swedish television producer Anna Eberstein. Hong and Grant reunited briefly and she gave birth to Grant's third child, a son named Felix, in December of that same year. In December 2015, he and Eberstein had their second child, a girl. Their third child, another girl, was born in March 2018, and they married on 25 May 2018. In 2011, Grant appeared at the Liberal Democrats' conference on the News International phone-hacking scandal, where he briefly met then-party leader Nick Clegg. Grant said that he was attending the Conservative and Labour conferences as well, but told Lib Dem activists that "You, more than any of the other parties, have a good bill of health. +more You have never been in bed with these scumbags. ". In the 2015 UK general election, Grant expressed support for Liberal Democrat MP Danny Alexander and later hosted a dinner for the Liberal Democrats, in which he met the winner of a draw of donors to the Liberal Democrats. In an email sent by former Liberal Democrat leader Paddy Ashdown, Grant wrote: "I am not a Lib Dem, a Tory, a Labourite or anything in particular but I recognise political guts. +more" In the 2015 election, he endorsed two Labour candidates: Tom Watson and his former agent, Michael Foster. During the 2019 UK general election Grant campaigned for tactical voting to stop a Conservative majority and Brexit. He was seen canvassing with Liberal Democrats candidates, Labour candidates, and independent Dominic Grieve. As a young boy, he played rugby union on his school's first XV team at centre and also played football. He is a fan of +moreC. '>Fulham and is also a supporter of Scottish football club Rangers. He continued to play in a Sunday-morning football league in south-west London after college and remains an "impassioned Fulham supporter". His other interests include tennis and snooker. In 2011, the BBC apologised after Grant made an offhand joke about homosexuality and rugby when he was invited into the commentary box during coverage of an England v Scotland game at Twickenham Stadium. Talking about playing rugby during his school days, Grant said: "I discovered it hurt less if you tackled hard than if you tackled like a queen". Relationships with co-stars After production on Restoration ended, Grant's co-star, Robert Downey Jr. +more, revealed that he and Grant did not get along during filming. Downey said: "I kinda think he's a jerk. Don't know, I just think he is. My personal experience with him is I think he's this kind of self-important, kind of, like, boring flash-in-the-pan asshole Brit. " In 2018, Grant confirmed the on-set tension he and Downey had had, stating: "He [Downey] hated me. He took one look at me and wanted to kill me. I was so hurt. " As a result of Grant's confirmation of their decades-long feud, Downey went to Twitter to make amends with Grant, to which Grant agreed. In addition to the confirmation, Grant also said that he and Drew Barrymore did not get along during production of Music & Lyrics. "Well, Drew, I think did hate me a bit. +more But I admired her. We just were very different human beings," Grant said. "She was very L. A. and I was an old grumpy Londoner. The funny thing is, although it was fractionally tense on the set of that film, I think the chemistry is rather good between us. Sometimes tension makes a good crackle. " Barrymore had also been one out of three leading ladies Grant listed whom he did not get along with, the others being Julianne Moore and Rachel Weisz. However, on a Graham Norton Show appearance, Grant told Graham Norton he did not know why he mentioned Weisz and he was probably "going for a 'comedy triple'". He is also on good terms with Barrymore and appeared on The Drew Barrymore Show. Grant has praised many other female co-stars, including Sandra Bullock, Sarah Jessica Parker, and Emma Thompson, and Meryl Streep, who co-starred with him in Florence Foster Jenkins and was "a genius" according to Grant. He referred to his Bridget Jones's Diary co-star Renée Zellweger as "delightful. +more" In 2020 he admitted he had always liked The Undoing co-star Nicole Kidman, saying she was a "silly Aussie girl. ". Grant is a patron of the DIPEx Charity, which operates the website Healthtalkonline. He is also patron of the Fynvola Foundation, named after his late mother; it supports the Lady Dane Farmhouse, a home in Faversham for adults with learning disabilities. Since his mother's death in 2001, Grant has worked as a fundraiser and ambassador for Marie Curie Cancer Care, promoting the charity's annual Great Daffodil Appeal on several occasions. He is also a patron of Pancreatic Cancer Action. Alvário B. saved page Humberto C. saved Leonardo O. liked page Elias M. saved page Patrik L. liked Jack S. saved page Inaya F. saved Chandran S. liked Ievstafiy S. saved Yeni Y. saved
My name is Bonnie Brunner. I am the owner and Art Instructor for the smART Room Studio in Cary, NC. My art studio has been providing curriculum-based art classes, specifically for Homeschooled students, since 2001. Classes are available for students 5–18 years of age. The class is not a test of skill and talent, but rather a place where they can improve their skills, learn, explore, and love making art.
Q: How would i convert this bat file to shell script for linux loading a java program This is the bat file: @echo off "I:\Program Files\Java\jdk1.7.0_17\bin\java" -Xmx1300m -cp data/CompiledFiles;deps/poi.jar;deps/mysql.jar;deps/mina.jar;deps/slf4j.jar;deps/slf4j-nop.jar;deps/jython.jar;log4j-1.2.15.jar; server.Server pause What would the shell script equivalent be? This bat file loads up a java server program that should be compatible with linux but I am not good with shell script. Thanks for the help. A: In case you are fine with the default Java interepreter on the system: #! /bin/sh java -Xmx1300m -cp data/CompiledFiles;deps/poi.jar;deps/mysql.jar;deps/mina.jar;deps/slf4j.jar;deps/slf4j-nop.jar;deps/jython.jar;log4j-1.2.15.jar; server.Server Otherwise: #! /bin/sh /path/to/executable/java -Xmx1300m -cp data/CompiledFiles;deps/poi.jar;deps/mysql.jar;deps/mina.jar;deps/slf4j.jar;deps/slf4j-nop.jar;deps/jython.jar;log4j-1.2.15.jar; server.Server A: should be very similar: #!/bin/sh java -Xmx1300m -cp data/CompiledFiles;deps/poi.jar;deps/mysql.jar;deps/mina.jar;deps/slf4j.jar;deps/slf4j-nop.jar;deps/jython.jar;log4j-1.2.15.jar; server.Server read the pause keeps the window open, I dont know if thats really intended, so maybe remove the 'read'
Philosophy and Culture Public Philosophy and Outreach If You Want to Do Good, Should You Get a Philosophy PhD? . June 28, 2015 at 6:09 pm 19 Suppose you wanted to choose a career based on how much good it will allow you to do. Assessing careers with that in mind is one of the aims of 80,000 Hours, a non-profit organization co-founded by philosopher Will MacAskill. The group looks at four aspects of a job: (1) Role Impact — the extent to which the career enables you to help others; (2) Career Capital — the extent to which the career allows you to develop skills, connections, and credentials useful for pursuing future opportunities; (3) Personal Fit — how well you'll do at the job; and (4) Job Satisfaction — whether you'll enjoy the work. They recently applied this framework to pursuing a PhD in philosophy: Philosophy, especially some areas within ethics and political philosophy, is plausibly a high-value area for research, and, if one is successful within philosophy, may also provide a good basis for impact via being a public intellectual. However, because of the current nature of the academic job market for philosophy, and because a philosophy PhD scores poorly in terms of career capital and keeping one's options open, we currently believe that a philosophy PhD is unlikely to be the best choice for the vast majority of people who are considering that option. It's important to note that almost all professional philosophers who have written publicly on this topic advise against aiming to become a philosopher as a career, unless "there is nothing else you can imagine doing."… You can read the entire "career profile" for Philosophy PhDs here, and a post at the 80,000 Hours blog summarizing it, by MacAskill. He emailed me about them, and asked that the Daily Nous readership take a look and provide some feedback. There are very interesting questions to take up here regarding how pursuing a career in philosophy measures up along each of the four aspects. Regarding philosophy's "role impact" (beneficence), MacAskill seems to think that some philosophical developments can produce a lot of good, but that such developments are rare and brought about by a very small number of philosophers. He thus discourages the choice of philosophy PhD unless you get into a very good program (more on that below). If his advice were taken seriously, there would be many fewer philosophy PhDs. Yet I wonder how large the philosophical community needs to be in order to produce the excellent, high-impact philosophy he favors. Such work is not developed in a vacuum. Just as interesting is his take on philosophy's negative impact. Here are his examples in the blog post: "Marx helped give rise to Communism, which was a Bad Thing; Nietzsche heavily influenced National Socialism which was a Very Bad Thing; Ayn Rand gave rise to Objectivists who are, like, really annoying." MacAskill also makes much of the fact that philosophers—often highly successful ones—warn people away from the career. Here's a representative quote he lifts from The Philosophy Smoker: If you find that the quality of your life is lowered by having a profession where you constantly feel mediocre, like you're not doing enough, like others are better than you, like your work is valueless, GET OUT NOW. No, seriously. It only gets worse after grad school, in my experience. You're looking at a lifetime of rejections. That's what professional philosophy is: an incredible string of rejections, with rare successes in between. And even if you DO avoid rejection (your paper is accepted to a conference! It gets published! You even write a book!), guess what? The best you can hope for is for others to attempt to prove that you're wrong. What if you're going to go ahead and do it anyway? The full profile includes this bit of blogospheric bait: We would recommend pursuing philosophy as a career only if one has explored and rejected other career options, and only if you get into a top-twelve PhD program: Berkeley, Columbia, Harvard, MIT, Oxford, NYU, Pittsburgh, Princeton, Rutgers, Stanford, UCLA, and Yale. Why those 12? We haven't investigated this in as much depth as we would like, and we're not convinced about the reliability of the data, which is often patchy. However, we estimate that the chances of ending up in a tenure-track or equivalent academic post if you enter a top-12 PhD program to be about 60%…. We came up with this list by taking the product of the Philosophical Gourmet Guide's mean scores of departments (as a measure of quality of position obtained after receiving the PhD) multiplied by the probability of entering a tenure-track or equivalent position according to Jennings' placement data. We then added in Oxford (which wasn't included in Jennings' placement data but would certainly have made the top ten if it were), and Pittsburgh (which performs well in a ranking of departments by how many junior philosophers in top-20 Gourmet guide departments the department has placed). This isn't intended to be a definitive top-12 ranking; if you're considering doing a PhD in philosophy it's worth consulting the Jennings data, the Gourmet Guide, and finding out as much as you can about the individual departments to see what's a good fit for you. I appreciate the "not-definitive" disclaimer. In my view, which 12 schools are on this list is the least interesting thing about this whole post, but if that is what you want to argue about, be my guest. I will note, though, that the youngest of the examples MacAskill gives of a high-impact philosopher, Nick Bostrom, didn't go to any of these schools. The philosopher who clearly inspired this project, and who is also mentioned on the list, Peter Singer, did (he got a B.Phil at Oxford). He is a very high-impact philosopher, but it is worth recalling what he has said about why he went into philosophy: Perhaps what swung the decision towards philosophy was that the philosophy department's faculty and students used to get into lots of interesting debates in the local pub on important issues like morality, God, free will… I wanted to think about the Big Questions. It isn't clear he was going for impact. If he was, would he have chosen philosophy? So, should one choose to pursue a philosophy PhD? Lots to discuss here. Categories Philosophy and CulturePublic Philosophy and Outreach Tags beneficencecareerimpactjobsPhDphilosophy As an ex-philosophy grad student and a former visiting instructor and adjunct now teaching high school students, I'll say that you have a better chance of impacting people's lives teaching high school students, just based on volume and time of contact. I, personally, find it infinitely more rewarding.Report As someone from the Social Sciences deeply into Philosophy, I would like to mention a few things about the false statement below. I'm not sure whether it was meant to provoke and address a wide audience, as it seems that way, but I would like to mention a few things anyway. "Marx helped give rise to Communism, which was a Bad Thing; Nietzsche heavily influenced National Socialism which was a Very Bad Thing; Ayn Rand gave rise to Objectivists who are, like, really annoying." It is not right, logically speaking, to say communism or national socialism or any political ideologies exemplified in reality were caused by Marx, Nietzsche (or [insert philosopher's name]). First of all, the ideas that were appropriated by the progenitors of very negative political ideologies during dark periods in the last century were falsely or misguidedly selected by the parties to further their purposes. For instance, Communism envisioned by Marx were definitely not the kind of communism that were implemented by the Soviets. Marx utopia ultimately got rid of the state, the Soviets implemented a totalitarian state. Nietzsche was used by the Nazis as ideological tools, such as to inspire soldiers to war (falsely), and the decimation of jews. Nietzsche himself despised just about anyone who couldn't think for themselves, including the Germans. (Not sure about Ayn Rand, I'm not sure how she is conflated with other 2). Second, what led to Nazi Germany and the Soviet Union had many other political and economic forces that philosophers had no control or did not even know. How could a few individual's, even taking into account the influence and strength of their philosophies, be said to involve millions of people, large scale political action, and massive changes in social and economic structure. This ignores completely the way the world was like before and why people were dissatisfied with it and had dreams of better societies. I think the author gives way too much credit to philosophers, about events that happen, while at the same time discrediting way too much the ideas that they developed and thought about and what they mean, by making such false equivalences.Report Yet Another Anon Grad Student "Marx helped give rise to Communism, which was a Bad Thing; Nietzsche heavily influenced National Socialism which was a Very Bad Thing" Not to be that guy, but that's kind of a crappy comparison. Marx actually developed and advocated socialism. In contrast, Nietzsche was rabidly anti-Nationalist and anti-antisemitic. He just had his work twisted by his Nationalistic and antisemitic sister while he was incapacitated.Report Puzzled Grad Student I was fine with most of what the linked-to post said, but this line seemed rather unfounded and offensive: "on average the very best people tend not to go into these areas [ethics or political philosophy]" Really? Is there any reason to think that on average the best philosophers do not go into moral and political philosophy?Report Adam Omelianchuk Whenever I see posts like this that essentially ask the "Is it all worth it?" question with lots of reasons posited that answer "HELL NO!" but then further asks, "But what if you want to do it anyway…" I come back to this: I know that it is unlikely that I will get a good job after grad school, which if all ends well will take 8 years of my life; if I am lucky and live til I'm 80, I will look back on those years and say, "I really got to do what I wanted to do for a tenth of my life, and I'm glad I did it–that is more than most people get." I say this as someone who was in the working world for 10 years behind a desk before going to grad school. Yes, maybe I will work at some crummy desk job again in the future, but at least I will be able to do philosophy on nights and weekends; most importantly, I will get to read what I want and converse with the people most important to me.Report This is very North America-centric and ignores the vast amount of philosophy work being conducted in Europe and Asia. It also ignores the great contributions philosophy has made via the disciple rather than via individuals. Ethics, political philosophy, philosophy of human rights all have significant, ongoing influence over collective and individual decisions at all levels of social interaction. This goes largely unrecognised by the general public because philosophy is oven subsumed by more popular titles but that doesn't mean there should be fewer philosophers, it just means we need to become better communicators.Report Ciaran Cummins Christ on a bike, when will this monomaniacal view of academic philosophy end? As Monica rightly said, this post (and similar posts/articles about philosophers' self-flagellation) ignores swathes of philosophical work being carried out in other parts of the globe (not to mention by the philosophically-inclined in other university departments). Perhaps if philosophy phd's were not presented in such a formulaic manner, then there'd be less worrying and self-loathing by those with them and those thinking about pursuing them. Perhaps if these individuals were pointed in other directions to go with their phd's (work outside of philosophy departments but in relation to your area(s) of interest, or in far less traditional academic career trajectories), then the idea that professional philosophy is and can ONLY be, "an incredible string of rejections, with rare successes in between" would stop being peddled.Report If you want to do good, should you be involved with, support, or listen to 80,000 hours? There are a few reasons to think the answer is 'no'. For instance, they are quite annoying and patronising, and people are put off by annoying and patronising people and might want to reject what they say out of hand. This might be irrational, but people can be irrational. I take it the idea is to make things better in the world, and if your approach puts people off then (even if your claims are true about what careers people should take) you shouldn't take this approach.Report Richard Yetter Chappell Hi Grumble, what aspects of their presentation do you find "annoying and patronising"? It would seem unfortunate to have this effect on some readers, if it's avoidable, so I expect that more specific feedback here could be very helpful for them.Report How about a post on the supposition? Should we really choose careers that will 'do the most good'? Even if so, should we advise people to do this? Should we do it, or advise people to do it, by trying to pick the career that will do the most good? It is very, very, far from obvious that we should answer any of these questions in the affirmative. Speaking for myself, I chose philosophy in part because I wanted answers to just these kind of questions, not because I knew the answers to start with and saw philosophy as the right way to apply them in my life.Report Avi Z. @Puzzled Grad Student: +1. E.g., Williams, Rawls, Singer, Parfit. The view that ethics is somehow a less rigorous field than M&E is ridiculous. Re. the overall issue: Graduate study in philosophy could be viewed as similar to studying to become an artist. One must be motivated by passion because few will make a decent living either in philosophy or in the arts. There is a perfectionist argument for pursuing a self-transformative passion such philosophy or the arts and there are reasons for thinking that this self-transformative element has some spin-off benefit to others under one's influence. Surely, though, if one had a passion for the law and became a human rights attorney, or for medicine and devoted oneself to preventing disease in impoverished places, one would be doing much much more for the world in a direct and evident way than teaching or writing philosophy could do. As a philosopher, the most good I could do would be to inspire my students to care about such things and become physicians or lawyers themselves who do good in the world (or whatever careers are their passion). I can help them make connections between their moral commitments and their careers. So, in this as in other ways, philosophy is a meta-discipline.Report Will MacAskill On negative impacts of philosophy: I do think that the precise word choice I used in both the profile and the blog post (e.g. Nietzsche 'heavily influenced') was mistaken and I've revised that – thank you. I'm fine with the idea that the examples of big social changes that have been linked to philosophers' views all would have happened anyway as a result of political or economic forces; that's something I don't know enough about (and wonder how confident one could ever be either way). What I'm very wary of is having a low evidential bar for examples of philosophy having a big positive impact on the world but a high evidential bar for examples of philosophy have a big negative impact on the world. The list is of philosophers who have been cited as influences on major world developments. If we were to go into more depth, we could investigate further the extent to which any of these philosophers made a difference (positive or negative). Note it doesn't matter whether these ideas were 'twisted' or not. The risk that as an intellectual your ideas will be bastardized and used for bad ends is a potentially grave one; if you are thinking about doing philosophy in order to have an impact on the world, then you need to bear that risk in mind.Report On anglocentrism: Yes the profile is anglocentric. I say that explicitly in the profile, but not in the blog post. Most of the audience of 80,000 Hours is based in UK, North America and Australasia. It's an open question to what extent this advice would be applicable to a career as a philosopher outside of the English-speaking world.Report @Grumble: On annoying and patronising: I would also love to hear more on which aspects you think are annoying, and which patronising?Report Oudeis I recall professors looking down on those who did not argue in as precise a manner as possible, be they students or other (junior) faculty/visiting professor, those who did not achieve some arbitrary, strange notion of rationality the professors called for, those who put forth very new, very different ideas instead of just arguing with one line from one article on one single subject in a dusty volume that no one will read. And what was annoying were professors' claims about "intuitions"; if you translate philosopher-speak into normal-speak and ask non-philosophers, the professors' supposed assessments of intuitions (moral and otherwise) and situations for that matter did not match up with the norm whatsoever.Report Annoying: being told, in effect, that you haven't done something that will 'make a difference' for the better by your choice of career. It seems implied that we ought to maximise the good with our choices, and it seems implied that if we didn't or don't then we're somehow subpar people. You don't say this explicitly of course, and maybe you don't intend to imply these things. But it still seems like veiled criticism from people who seem to see themselves as people as making a difference for the better – I.e there's an impression you see yourselves as better than everyone else, and that's annoying because it's not clear you are. Since it hasn't been shown yet 80,000 hours is making a difference for the better, it's annoying that you seem to expect people should listen to your advice. This feeds into the patronising aspect… Patronising: people who went to elite/privileged institutions, who are often (but not necessarily) people from privileged (economically, socially) backgrounds, telling others that they should pursue philosophy only if they can get into an elite/privileged institution. Thanks guys, but some of us aren't that lucky early in life (or at any stage) or didn't realise what careers we would like to pursue earlier enough to put the considerable effort in be in with a chance of attending an elite/privileged institution at some point in our lives. And now we're being told we shouldn't do something we enjoy (if we want to make a difference for the better) because it won't make a difference. Lucky you guys have figured everything out so the rest of us don't keep ruining the world.Report Jon Cogburn At one point in the black notebooks Heidegger denounces anti-semites. When a French philosopher recently went on national TV and cited that as proof that Heidegger was not an anti-semite, he was widely and justifiably derided. Yet people over and over again (see above) do the very same with respect to the manner in which national socialists (or Ayn Rand for that matter) used Nietzsche's texts. Of course Nietzsche contradicts himself everywhere, so we can find things that go against the Nazi's use of him. Some commentators take this to be a virtue, rather than a bug as it forces Zarathustra's disciple to stab Zarathustra in the back. I don't know (I quit Nietzsche for Schopenhauer years ago). In any case, the stuff Nietzsche wrote to get back at his anti-semitic brother in law should be seen as irrelevant when considering the connections between him and National Socialism. The views Nietzsche expresses over and over again about democracy, equality, violence, his views about the primacy of aesthetics, as well as what he did with Schopenhauer's metaphysics of will and also the manner he denounces his perceived opponents don't at all fit into the Walter Kaufmann whitewashing and were easily usable by the Nazis without any interpretive folly. And, to the extent that this is relevant, it should be clear that Nietzsche himself would have had nothing but contempt for well meaning liberals trying to sanitize his thinking.Report another nameless grad student As a former activist now grad student, I have wrestled with whether I ought to continue in philosophy, especially given the threat of climate change. Trying to make it through grad school gives me very little free time to help out in the movement. Sean(10) asks whether we should be choosing careers that 'do the most good', and I have long questioned myself on this. I ultimately chose philosophy for two reasons. First, because I think it is a valuable discipline that helps make life worth living and humanity worth saving, even though it doesn't have an immediate practical impact. What a neat species we are, producing interesting questions and ideas, culture and art! What would life be like without these things? Second, because it is what I wanted to do. I think that a world full of people pursuing careers they find fulfilling is better than a world where people sacrifice their identities in order to do good. Sue Wolf's paper on moral saints is highly relevant here. That said, I do think we owe it to students to convey the value of the discipline through inspired teaching, owe it to ourselves to get involved with social causes we believe in (if only by donating money) and owe it to society to speak out on important issues relevant to our times (tip of the hat to the daily nous for the recent posts).Report Molly Mahony I could not help but notice that the "team" of 80,000 hours are primarily white males, with the exception two women, one a research advisor and one a volunteer.Report
Accounts of Materials Research (nach ISO 4-Standard in Literaturzitaten mit Acc. Mater. Res. abgekürzt) ist eine monatlich erscheinende Fachzeitschrift, die von der American Chemical Society herausgegeben wird. Die Erstausgabe erschien im Oktober 2020. In der Fachzeitschrift werden Artikel, welche prägnante persönliche Rezensionen und Perspektiven, die aktuelle Forschungsentwicklungen in allen Aspekten der Materialwissenschaft und -technik beschreiben, veröffentlicht. Chefredakteur ist Professor Jiaxing Huang von der School of Engineering der Westlake University. Der CiteScore betrug 2021 3,4. Einzelnachweise Englischsprachige Monatszeitschrift Ersterscheinung 2020 Fachzeitschrift (Vereinigte Staaten) American Chemical Society
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FREMONT, Neb. – For the second time this season, the Dakota Wesleyan University football team will endure a two-game road stint as they will face off against (RV) Midland University at 1 p.m. Saturday in Fremont, Neb. The Tigers took the lead early in the Blue & White Days football game against Dordt College. DWU marched on a 13-play, 91-yard drive that ended with a 25-yard field goal from Tate Gale (Irene, S.D.). The Defenders answered with four-straight touchdowns as the teams headed to the locker room with the score, 26-3 in favor of Dordt. The Tigers got a spark early in the third quarter when Daniel Libolt (Chambers, Neb.) raced down the right sideline for a 94-yard kickoff return. DWU found the end zone again with 3:18 left to go in the third quarter as Shaye Slaughter (Harrisburg, S.D.) scampered for a 16-yard run to make the score 36-16. Dakota Wesleyan scored one more time with a 52-yard touchdown reception from Libolt on his only catch of the game, but it was not enough as the Tigers fell 50-23 on Saturday. Slaughter finished 11-of-23 passing for 173 yards through the air with a touchdown and 14 yards on the ground with a score. Luke Loudenburg (Canova, S.D.) rushed for 51 yards on 14 attempts. Spencer Neugebauer (Mitchell, S.D.) caught three passes for 75 yards and Jonny Withrow (Kimball, Neb.) led all receivers for DWU with four catches on the day. Tyler Wagner (Webster, S.D.) tied a season high in tackles with 13 tackles. Cody Reichelt (Mitchell, S.D.) and Alan Murtic (Phoenix, Ariz.) both finished with 10 tackles. The all-time football series between Dakota Wesleyan and Midland University has been a close one, as the Tigers are 15-16 against the Warriors. The last time DWU was defeated by Midland was in 2011 in Fremont, Neb. Ross Cimpl is currently in his seventh season as the head coach of the football program. He has coached the Tigers to seven-straight winning seasons. He currently sits second on the all-time wins list at DWU with 45 victories. Jeff Jamrog is in his third season as head football coach of Midland University. Jamrog has coached two straight winning season and has posted a 7-4 career record when coaching at home. The Warriors are currently 5-2 coming into Saturday's contest with a GPAC record of 3-2. Last Saturday, Midland defeated Hastings College 36-15 in Hastings, Neb. The Warrior offense is led by quarterback Payton Nelson who leads the team in rushing and passing yards thus far. He has rushed 86 times for 455 yards and four touchdowns. Through the air, the junior signal caller has thrown for 1,506 yards and 15 touchdowns on 104-of-193 passing. Defensively, Midland relies on linebacker Wyatt Tremayne who has collected 53 tackles and has 5.5 tackles-for-loss on the season.
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BENGALURU: The Karnataka Electricity Regulatory Commission (KERC) has fixed Rs 4.36 per unit as the new tariff for new grid-connected megawatt (MW)-scale solar photovoltaic plants. This is the tariff solar developers selling power to the grid will get from the distribution utilities. The new tariff is applicable to solar projects that will sign power purchase agreements (PPAs) with distribution utilities during the financial year (2017-18). The tariff is also applicable to all those grid-connected MW-scale solar PV plants for which PPAs were signed earlier, but will go on stream only during this financial year. The regulator has allowed a capital cost of Rs 4.40 crore per MW, and a return on equity (RoE) at 16% for developers. The developers can raise debt up to 70% of project cost and the regulator has allowed debt repayment over a period of 12 years.
Intel's booth at CES is always a great place to get a peek into the future of personal computing. At this year's CES, Intel had the several Android prototypes that were running on 32mm Intel Atom processors. These are the first Android phones that we've seen to be running on intel's architecture, and the tech giant was using the prototypes to demonstrate the benefits of Atom over other mobile processors. The actual hardware on display at the booth was a developer device that is never coming to market. The prototypes were all running Android 2.3 (Gingerbread), and came loaded with software that was meant to show off the capabilities of Intel's mobile chipset. In my hands on with the prototypes, I was surprised by how fast and fluid the phones' performed. Asphalt 6, a game that normally stutters on dual-core phones, had no issues running on the single-core Atom. Along with increased gaming performance, Intel claimed that the Atom processor would support hyper-threading (for more efficient management of resources) and would help with conserving battery life. Intel claimed that the prototypes had a battery life of about 6 hours while playing video, however I had no way of testing that claim with just my short time with the phone. I asked if the Atom processor would only work with Gingerbread, to which Intel replied that they would be working hard to support Ice Cream Sandwich and all future versions of the OS. Unfortunately, Intel still has more testing to do and gave me no real time frame for when we would start seeing the first Intel powered Android phones.
using System; using System.Globalization; using Xamarin.Forms; namespace MyQuizMobile.Converters { internal class AnswerResultConverter : IValueConverter { public object Convert(object value, Type targetType, object parameter, CultureInfo culture) { return (string)value == Constants.CorrectAnswerOptionText; } public object ConvertBack(object value, Type targetType, object parameter, CultureInfo culture) { return (bool)value ? Constants.CorrectAnswerOptionText : Constants.WrongAnswerOptionText; } } internal class AnswerResultTextConverter : IValueConverter { public object Convert(object value, Type targetType, object parameter, CultureInfo culture) { return (string)value == Constants.CorrectAnswerOptionText ? "Richtig" : "Falsch"; } public object ConvertBack(object value, Type targetType, object parameter, CultureInfo culture) { return null; } } internal class QuestionTypeAnswerConverter : IValueConverter { public object Convert(object value, Type targetType, object parameter, CultureInfo culture) { return (string)value == Constants.QuestionCategoryQuizText; } public object ConvertBack(object value, Type targetType, object parameter, CultureInfo culture) { return null; } } }
Former Fall River pastor's street evangelism leads to arrest Greg Sullivan Tom Cabral figures in order to keep doing his work for God, he's going to have to fight for his rights as a citizen. The former pastor of Redemption Fellowship Church in Fall River on Friday night was arrested in Fort Myers, Fla. while conducting street evangelism in the city's popular restaurant district. According to the arrest report, Cabral was charged with resisting an officer without violence and violation of a municipal noise conveyance ordinance. On the second page, the probable cause statement, the first charge is worded "obstruction of a law enforcement officer during a criminal investigation." Cabral is due in court on Oct. 20. A teacher at the Summer Christian School in Fort Myers, Cabral said he plans to fight the charges and is exploring his legal options. He said he has been preaching the Gospel of Christ in the restaurant district for about a year and doing so within his First Amendment rights. A YouTube video picking up the arrest in progress shows Cabral wearing an Aker System for voice amplification and he repeatedly can be heard, through the Aker, asking why he was being arrested. Cabral said that his Aker does does not operate above the maximum decibel level allowed by city ordinance. According to the city website, that level would be 65 dBa for a public space between 7 p.m. and 11 p.m. Arresting officer Martin Davila's report said Cabral violated the the city's Article V Section 54-196 ordinance because his noise (voice) could be heard from more than 25 feet away. Cabral said another officer the previous week had told him the distance was 50 feet. Cabral said that at the time of his arrest on Friday night, two nearby bands were playing music at a noise level well above his own. The arrest time is listed as 9:14 p.m. Fort Myers' Article 5 (Noise), Section 54-196 (2) lists 50 feet as the minimum distance constituting a violation for sound-producing or sound-amplifying devices between the hours of 10:30 p.m. and 7:00 a.m. Section 54-196 (3) [Commercial advertising devices] says the use of a sound amplifier "for producing or reproducing sound which is cast upon public streets for the purpose of commercial advertising or attracting the attention of the public to any building, structure or area" constitutes an act in violation of Article 5. In Section 54-197, 25 feet is mentioned as the sound violation minimum distance for any "conveyance, aircraft, vehicle, vessel, motorcycle, or bicycle on the streets, alleys, waterways, or other public places in the city." Davila, Cabral said, had approached him about 15 minutes before the arrest asking if he had been blocking the street. The report said that an EMT at a nearby medical call said a man preaching with a microphone had blocked his ambulance en route to the call. Cabral said he recalled no ambulance going by. Davila's report said he told Cabral that if he continued to use the speaker, he would be cited for violating the noise ordinance and that continued speaker use after citation could result in arrest. "He never said that to me it's that simple," Cabral said in a Facebook message. "It's listed in the report as a 25 Foot ordinance where one of the city ordinances States it's 50 ft." The report said Davila returned to the medical call area before going back on patrol, where he saw Cabral continuing to preach through the speaker. The report said Davila asked Cabral for his name in order to cite him and when Cabral repeatedly refused to give his name or identify himself by any means, the officer arrested him for obstruction of a law enforcement officer during a criminal investigation. Cabral said Davila had, after the first meeting, returned and told him to "shut it [speaker system] down" and asked him his name. Calling upon the street evangelism training he received from Gospel of God Ministries, Cabral said he told the officer he didn't have to give his name unless he was breaking the law, and he asked the officer his name, and then the name of the officer's superior. Cabral said officers do not always know the exact details of every ordinance. He said the officer did not comply with his name requests. Cabral said he told the officer he would continue his street evangelism unless told what he was doing was wrong. At that point, Cabral said, Davila spun him around and handcuffed him and moved him into the squad car. The YouTube video shows the standing Cabral, during the handcuffing, repeatedly and calmly asking, "Why are you arresting me, sir?" Cabral cautioned watchers of the YouTube video that it is his fellow evangelists, not Officer Davila, who can be heard responding to his question. Cabral said he did not learn what the charges against him were until Davila handed him the report at the police station. Cabral said that in previous meetings with Davila in the restaurant district, the officer had displayed "not the most comfortable demeanor." He said complaints about street evangelism are common but that other Fort Myers police officers, acting on complaints, have been far more civil toward him and have acknowledged his First Amendment rights. Cabral, a Somerset High School graduate, said he was handcuffed for two-and-a-half hours, booked and fingerprinted but, due to COVID-19 concerns, not jailed. He said he was released on personal recognizance. Cabral said he is suspicious of having been targeted on Friday night. He said another preacher, using a megaphone, evangelized in the same area Saturday night and "nobody bothered him." Married and the father of two daughters in their upper teens, Cabral said when he finally returned home, his family had settled down. "They said they knew it would happen eventually," he said. "Being an evangelistic Christian is going to be costly sometimes." Cabral said he's heard of a Fort Myers area attorney who has three times out of three successfully defended a street evangelist who had been arrested and charged. Asked to describe his street evangelism style, Cabral said in a Facebook message, "When I share the gospel I speak about grace and mercy, sin and salvation, Heaven and Hell, in other words I try to preach the whole counsel of God. My goal is not to persuade people to say a prayer but my goal is to preach the whole truth about salvation and trust God for the results." Cabral conducted conspicuous street evangelism in Fall River in the previous decade. His most visible spot was the intersection of Plymouth Avenue and Rodman Street. He would often carry an approximately six-foot wooden cross. He also preached in front of Fall River District Court on South Main Street. He said he recalls five times in Fall River when he was threatened with arrest by police. In a Facebook comment on a post of the YouTube video, Cabral said, "I'm a firm believer in respecting authority especially the police and I have no malice towards them but when someone acts in an unbecoming way these things need to be made known so that the rights of all types of people can be protected. I have quite a few policemen friends and I utterly respect their work. I am not in the least bit upset at this police officer but I am not pleased with the way he handled me or this case. Just remember if it happened to me it can happen to you too." Cabral said he will be back in Fall River on family business this weekend and plans to evangelize at Fall River District Court on Friday. Email Greg Sullivan at [email protected]. Follow him @GregSullivanHN.
Hate groups Curfew? Argentina's African roots ECONOMY | 23-11-2020 15:51 Without environmental guarantees, EU-Mercosur trade deal faces uncertain future Historic free-trade agreement between the European Union and the Mercosur regional bloc, announced more than a year ago after more than two decades of negotiations, stuck in limbo due to environmental concerns. James Grainger Editor-in-Chief, Buenos Aires Times. In this aerial view the red dust of the BR230 highway, known as 'Transamazonica,' mixes with fires at sunset in the agriculture town of Ruropolis, Para state, northen Brazil, on September 6, 2019. | AFP The long-trailed free-trade agreement between the European Union and the Mercosur regional bloc, announced more than a year ago after more than two decades of negotiations, is still shrouded by uncertainty due to the absence of binding mechanisms that offer environmental guarantees, especially in relation to the Amazon rainforest. This agreement would potentially create a huge market of more than 750 million people, but EU leaders and the heads of several European governments consider its ratification in its current form to be unfeasible, leaving the door ajar to the possibility of a reopening of negotiations. The documents related to the deal are currently going through a bureaucratic phase of legal reviews and precise translations before being transmitted to the European Council, which groups together the 27 EU leaders. The deal's final text will then be submitted to each national parliament for ratification. 'We will not submit it' Grain means pain, corn meets scorn In October, the executive vice-president of the European Commission, former Latvian prime minister Valdis Dombrovskis, said that it would not be possible to ratify the existing agreement without clear and legally binding environmental commitments. "In its current form, we will not submit it for ratification, and I believe that even if we do, we will not be successful," he said, without mincing his words. In order to move forward, the EU needs the Mercosur nations to provide "significant results and commitments," said Dombrovskis, adding that it is necessary to define "durable solutions for the Amazon region." Export cap reversal rounds off chaotic week of agro tensions Criticism has already firmed up in several regions. The Austrian and Dutch parliaments (as well as the Walloon regional legislature in Belgium) have both ruled out ratifying the agreement in its current form, while Ireland, Luxembourg and France have also expressed strong reservations. The ratification of the agreement requires a unanimity "which at the moment there is not," a diplomatic source in Brussels told AFP. Re-opening talks? Budget 2020: 60% used to pay pensions, social plans or subsidies The core of the issue to hand is the chapter of the agreement that refers to sustainable development, which does not feature settlement mechanisms for disputes. It also highlights the use of best practices, but only says their application is voluntary. Several European nations therefore fear that an expansion of the potential market for Latin America's agricultural and meat products will in turn lead to a dramatic deforestation in the Amazon region, in order to meet an increase in production. A recent report by the French government seeking to define its position concluded that an increase in the production of beef to serve the European market would represent an annual increase of 25 percent in the levels of deforestation in the Mercosur region, potentially affecting an area equivalent to the Netherlands. What we learned this week: January 9 to 16 The leaves a straight choice between two alternatives: reopen negotiations, limiting them to the issues that prevent ratification, or dividing the agreement into two – one commercial and the other political. With uncertainty hanging over the deal, Uruguayan President Luis Lacalle Pou was explicit in identifying the problem back in September: "The obstacle today is the Amazon. It is an issue that worries Europe," he said at a press conference. Uruguay expected significant progress to have been made on the deal during the latter half of this year while it holds the pro-tempore presidency of Mercosur, but results have been unsatisfactory. Argentina is due to take over the bloc's leadership on December 16. CGT airs concerns over CFK call for 'integrated' health reform However, cracks in Mercosur are clearly evident, and this has made it more difficult for the quartet to hold a united position as a bloc. Dissonant voices Too cool for school, or too hot? One Latin American diplomat in Brussels highlighted that the leaders of the two Mercosur heavyweight nations, Argentina's Alberto Fernández and Brazil's Jair Bolsonaro, have still not yet had a bilateral meeting, despite the Peronist leader having been sworn-in almost one year ago. Bolsonaro did not even attend his peer's inauguration. "It's like Angela Merkel and Emmanuel Macron not speaking to each other," the same source told AFP. Jorge Neme, international trade secretary at the Foreign Ministry in Buenos Aires, said in November that "we can discuss whether the agreement was well or badly negotiated, but it is a matter of State – the government and the Foreign Ministry have decided to respect the closing of the agreement." Crop U-turn peeves importers, lays bare Argentina's infighting A spokesman for the Paraguayan Foreign Ministry, meanwhile, told AFP that the environmental concerns were opportunistic. "It is because of those fires that occurred in our region," the spokesperson said, referring to huge fires in the Amazon region in the first half of this year. Responding to a request from AFP, the Brazilian Foreign Ministry declined to comment. Government set to authorise re-opening of the cinemas Bolsonaro has maintained his position throughout the debate, questioning data on deforestation in the Amazon and going so far as to accuse environmental NGOs of promoting crimes in order to attract greater attention. In turn, Brazil's Vice-President Hamilton Mourao has said the criticism is a result of very powerful "lobbying by European farmers." The deal, for now, remains in limbo. INDEC reveals inflation reached 36.1% in 2020 by Aldo Gamboa & Bureaus, AFP In this news personalities: More in (in spanish) Los picnics urbanos que están de moda Conocé a Leni, la hija de Heidi Klum que acaba de debutar como modelo Conocé el interior de la casa de María Vázquez y Adolfo Cambiaso Aparece la nueva generación de Ford Ranger Previous news of "Economy" IMF and Argentina making 'good progress' on new financing plan Wealth taxes and extraordinary contributions – how other nations handle it 'Wealth tax' could hit as three times more people than anticipated Night-time raiders are destroying US$100,000 soy bags – and farmers have had enough Global crop supply fears send soybeans to highest in six years The fallacy of 'deplatforming' Donald Trump Censorship is on the march Ads Space Most viewed of Perfil La desgarradora carta de la madre del joven ahogado en Tigre: "Esto se podría haber evitado" Las dos caras de Horacio Rodríguez Larreta: clases presenciales, pero sin vacantes Un fuerte sismo de 6.8 grados sacudió la provincia de San Juan El día que Evita conoció a Perón Diario Perfil batimes.perfil.com - Editorial Perfil S.A. | © Perfil.com 2006-2021 - All rights reserved Intellectual Property Registry Number 5346433 Address: California 2715, C1289ABI, CABA, Argentina | Phone: (+5411) 7091-4921 / (+5411) 7091-4922 | E-mail: [email protected]
The Free Library > General Interest/Informational > General interest > Washington Monthly > May 1, 2003 The Free Library > Social Sciences > Political science > Washington Monthly > May 1, 2003 The Free Library > Date > 2003 > May > 1 > Washington Monthly Charging ahead: America's biggest new export--credit cards--could bring down the world economy. <a href="https://www.thefreelibrary.com/Charging+ahead%3a+America%27s+biggest+new+export--credit+cards--could...-a0101861608</a> MLA style: "Charging ahead: America's biggest new export--credit cards--could bring down the world economy.." The Free Library. 2003 Washington Monthly Company 29 Jan. 2020 https://www.thefreelibrary.com/Charging+ahead%3a+America%27s+biggest+new+export--credit+cards--could...-a0101861608 Chicago style: The Free Library. S.v. Charging ahead: America's biggest new export--credit cards--could bring down the world economy.." Retrieved Jan 29 2020 from https://www.thefreelibrary.com/Charging+ahead%3a+America%27s+biggest+new+export--credit+cards--could...-a0101861608 APA style: Charging ahead: America's biggest new export--credit cards--could bring down the world economy.. (n.d.) >The Free Library. (2014). Retrieved Jan 29 2020 from https://www.thefreelibrary.com/Charging+ahead%3a+America%27s+biggest+new+export--credit+cards--could...-a0101861608 FOR MOST OF THE LAST TWO GENERATIONS, the global economic system operated under a paradoxical division of labor. Americans consumed, while Asians--and much of the rest of the world--saved. The vast American consumer market helped drive the whole world economy. But since Americans were spending at such a prodigious clip, they weren't able to save much. That created two problems: There wasn't a lot of capital for business investment and even less to make up for the country's huge current account deficit--a function of our buying more from foreigners than we sell them. That's where the saving of the rest of the world came in. Foreigners saved so much that they had plenty of capital to invest--and where better to invest it than in the galloping, consumer-driven American economy? Foreign investors, banks, and other companies purchased American equities, treasuries, and greenbacks, and invested in the United States (According to a recent Merrill Lynch report, the United States absorbed nearly three-quarters of the savings of the world's major industrial countries in 2002.) This inflow of foreign capital has kept America's current account deficit stable and U.S. inflation low, making it easier for American consumers to keep on buying. Asians, meanwhile, needed our consumption-driven economy because their export-driven economies thrived on Americans who spent every dollar they earned, and then some. This division of labor may have been morally dysfunctional. But as a global economic order, it worked like a charm. Of course, economists long warned that the system was inherently unstable. If foreigners suddenly lost faith in the U.S. economy and pulled out their billions, the market would bid the value of the dollar down dramatically. Indeed, since the stock market bubble burst in 2000 that's already begun to happen. In the last two years, foreign investment in the U.S. economy has plummeted to levels last seen in the early 1990s. With America at war against terrorism, anxious economists now worry that rising anti-Americanism or just the war-induced strains on the American economy could prolong the foreign investment drought or dry it up even more, leading to a sharp devaluation of the dollar, and perhaps even a cycle of worldwide recession. There's no way to predict if any of this will come to pass. But the crux of the problem is that these possibilities remain outside America's control. The only way to truly solve the problem is for Americans to save more at home or sell more goods and services overseas. Ironically, though, what may bring the whole system crashing down once and for all is one of America's own most rapidly growing exports: credit cards. Sticky Rice, Stickier Debt Until the mid-1990s, consumers outside North America and Western Europe rarely ran up large amounts of personal debt. With the credit card market in the developed world still growing, big credit card companies did not focus on the developing world (which includes most of Asia). Countries like Thailand still hadn't developed large populations of middle class consumers. But traditional mores also played a role. In Asia, where people historically considered saving an important virtue and conducted nearly all transactions in cash, personal debt was less a fact of life than a source of shame. As recently as the mid-1990s, South Koreans saved more than 30 percent of their GDP, while Americans struggled to save a measly 1 percent (though U.S. home values and ownership rates, a form of savings, did rise). For a variety of reasons, however, the situation has recently begun to change. As some developing countries boomed during the 1990s, they germinated millions of new middle- and upper-class consumers who had more capital and more desire to purchase consumer goods and their own homes. Many of these new consumers were under 40--men and women less tied to traditional mores of saving. Many had traveled in North America and seen how Americans easily obtain loans, sign mortgages, and whip out credit cards. After the Asian financial crisis of 1997, which depleted much of the savings of this new middle class, credit was often the only way to keep buying. At the same time, the late-1990s financial crises prompted Asian, Latin American, and Eastern European governments to try to stimulate domestic consumption to boost national growth rates. Two key ways to do that were to lower rates of interest and ease the regulation of credit. Over the last three years in Thailand, Prime Minister Thaksin Shinawatra has toured the country to encourage Thais to spend more. In South Korea, the government has called on Koreans to borrow as much as possible. In China, the state has gone so far as to create whole new national holidays to give citizens more time to shop. Meanwhile, intensive lobbying by banks, finance companies, and credit card firms has prompted governments to lower the minimum-income bar for credit cards and other consumer loans. For the lenders, the motivation was obvious. Credit-card operations can generate returns of more than 50 percent, since card issuers often charge interest rates of more than 20 percent. As Noam Neusner noted in U.S. News and World Report, "for banks, personal, unsecured loans--[i.e. issuing credit cards or personal loans to people who are a high risk not to pay their balance] represent one of the most profitable niches." And as markets in the developed world became saturated, debt issuers turned to the developing world to keep their profits rolling in. This crucial deregulation has allowed banks and card companies to pursue a wider range of clients, many of whom have minimal savings and no credit history. In South Korea, for example, it has become so easy for lenders to issue credit cards that the local media reported last year that banks had mistakenly given household pets--which could hardly have a credit rating--their own credit cards. In golf-mad Thailand, card issuers have offered free links lessons. And credit-card issuers have pursued similar tactics across Latin America and Eastern Europe. Foreign governments and global lenders have both tried to encourage developing world consumers to open their wallets and global consumers have happily obliged. Until recently, credit cards were unheard of in China. Today, however, Chinese use plastic for more than $200 billion worth of transactions annually. India and Indonesia reported major increases in mortgage applications, consumer loans, and credit card purchases in 2002. Across Asia, Visa International increased the number of cards issued by 25 percent last year alone, and cash withdrawals using Visas rose by 44 percent. According to The Economist, households now account for nearly 40 percent of East Asian banks' total lending, up from 27 percent in 1997. Thailand and South Korea have become even more obvious examples of American-style spending. Visa says that total spending on its cards in Thailand is rising by more than 40 percent annually. In South Korea the story is the same. As one South Korean told The New York Times in December, the average Korean worker now carries four credit cards (more than 10 million South Koreans carry four or more, while the average bank worker carries between 10 and 15). Meanwhile, consumers in Eastern Europe, Latin America, and even Africa have actively followed suit. Schroder Salomon Smith Barney, an investment bank, estimates that between 1997 and 2001, household lending in Hungary, Poland, and the Czech Republic rose by more than 25 percent. As The New York Times recently reported, Russians also are beginning to utilize debt to pay for mortgages and large appliances. Household spending in South Africa, the biggest economy in Africa, has soared since 2000. And while Latin America has been hit by a series of financial crises from which, unlike Asia, it has not completely recovered, consumer spending--especially spending on credit--is rising there as well, in the region's more developed economies. As in the United States, the expansion of household spending in the developing world has had many positive impacts. It has not only helped buoy domestic economies hit hard by the economic shocks of the late 1990s but also provided new markets for foreign companies. Chinese acceptance of credit and auto financing, for instance, has helped Volkswagen make China its largest market; other automakers plan to follow suit. "The Chinese are becoming more used to financing. Once we establish the type of comprehensive GM financing systems we have in the US, we expect to see a huge jump in purchases," General Motors China head Philip Murtaugh told me last fall in Shanghai. Leading automakers are also developing plans to expand their product lines in Mexico, Brazil, South Africa, and Chile, in part because of the explosion of borrowing on credit--a development which mirrors the pattern in America during the early 20th century. Rising consumer spending has also filled many countries' tax coffers, since in most developing countries sales taxes are much easier to collect than income taxes--income-tax avoidance is very high. Yet the hard truth is that no one really knows what the impact of this consumer spending will be. These benefits could be outweighed by the potentially destructive impact of unleashing easy credit and American-style personal spending in developing nations with nascent systems of credit checks, unsustainable trade imbalances, and weak and opaque banking systems. In the United States, though financial companies have more leeway to lend to lower-income consumers than they used to, they are still subject to a range of state and federal regulations. Banks, credit card issuers, and other consumer lenders can also utilize America's well-developed system of credit checks to discover which potential customers are bad credit risks. Consequently, US. lenders generally are able to avoid lending or offering credit cards to high-risk clients. Most developing countries lack the regulations and credit-checking services to deal with their rising numbers of consumer loans, credit cards, and mortgages. In Mexico, for instance, few banks require card recipients to show any credit history; minimum income, or even knowledge of how to use a card. As one Mexico City taxi driver told The Financial Times, "There's always someone offering me free credit." In Hong Kong, the lack of regulations has allowed credit card companies to aggressively target university students, helping the students obtain a credit card in minutes with nothing more than a photo identification. (Last May, Hong Kong's Consumer Council, a research and advocacy organization, chastised the government for allowing banks and other card issuers to use misleading tactics in their campaigns for students.) Widespread corrupt practices, meanwhile, have led merchants in other countries to shun plastic altogether. When I traveled to Argentina in the winter of 2001-2002, I often found k difficult to convince retailers to take my American Express, the supposed gold standard of credit cards. Retailers had become so used to seeing fraudulent cards and other forms of questionable scrip issued by Buenos Aires banks and even provincial officials that they no longer trusted anything but cash. Meanwhile, the national government was taking virtually no steps to investigate any of the cards. Most merchants simply adopted a policy summed up by a sign in one cafe: "Se Acepta Dolares." As a result of so much fraud and so much easy credit, many lenders in the developing world have found themselves overwhelmed with bad consumer loans and huge numbers of personal bankruptcies. To take just one example, 2.5 million South Koreans have fallen into arrears on their credit-card payments, in a nation of only 48 million people. In February, South Korean banks estimated that nearly 8 percent of credit card bills in the country were outstanding for a month or more, roughly double the percentage in the United States, and last year South Korea suffered its largest number of personal bankruptcies ever. According to banking industry statistics, personal bankruptcies are also rising in China, Mexico, Argentina, Chile, Brazil, and Thailand. In Hong Kong, personal bankruptcies are soaring by more than 100 percent per year. Even small, isolated countries like Bolivia have been affected by the rolling wave of easy credit and bankruptcy. The rising tide of personal bankruptcies not only bears a social cost of broken families, domestic violence, and suicides, it also cuts into global lenders' ability to finance business loans. This isn't the case in the United States, because our capital base is vastly larger and deepen But in Asian countries with smaller capital bases the problem is immediate and acute. In South Korea, several large banks, including Kookmin, the country's largest lender, have seen their net losses rise over the past four quarters--Kookmin lost $173 million in the fourth quarter of 2002 alone--because of what analysts told The Financial Times was a pattern of "reckless lending to consumers [without] properly assessing the creditworthiness of consumers" As a result, Kookmin and several other large South Korean banks have had to increase their cash reserves to cover non-performing consumer loans; in so doing, they have sharply reduced their loans to businesses. In fact, this spring South Korea's credit card companies and banks have had to issue more than $1 billion in new shares in an effort to address a looming cash crunch, a move which has rattled South Korea's stock markets. A similar pattern has been observed in other countries in Asia, Latin America, and even Russia. Even major financial players can be affected. Last year, HSBC had to drastically increase its provisions for potential defaults, in part because of personal bankruptcies in Hong Kong, which thereby reduced the amount of capital HSBC had to lend. Drawing funds away from business investment can be a serious drag on economic growth. Banks reduce their capital bases, interest rates are forced up, capital becomes harder for businesses to raise, and companies slip into bankruptcy. Indeed, corporate bankruptcies in South Korea, Hong Kong, Thailand, and elsewhere in Asia have risen over the past two years, as many businesses have been unable to find new sources of financing from banks weighed down by portfolios heavy with non-performing loans. The decline in investment is often compounded by the binge-and-purge effects of high consumer debt, in which consumers run up huge credit card bills and then spend virtually nothing for months. This cycle can make it hard for retailers to make long-term business plans. Prominent economists have begun to realize the potential dangers excessive consumer lending poses to the developing world. Last fall, the International Monetary Fund's chief representative in Seoul, Paul Gruenwald, expressed serious concern that South Korea's economy could be undermined by the "booming" number of bad loans to households and high credit card delinquency rates. Gruenwald has advised the South Korean government to take measures to reduce Koreans' consumer spending binge, and the IMF has since issued several other warnings about excessive, unregulated consumer lending in the developing world. Taking the advice, the South Korean government recently has announced government measures designed to bail out cash-short Korean credit card companies and restore banks' liquidity. Kim Gwang-Lim, South Korea's vice minister of finance, warned that if such a bailout does not succeed, "the potential impact from credit card companies' problems on the financial markets will be significant. Such problems could trigger chaos ... and a possible collapse of the entire financial system." Unsustainable Development As 1997's Asian financial crisis demonstrated, crises in one developing nation's economy can rapidly spread to others, sparking a wave of destabilization throughout the world economy. Indeed, many of the countries experiencing rapid run-ups of consumer credit are those which went through snaps of boom and bust in the middle 1990s. Beside the growth of easy personal credit in Asia, economic weakness in Mexico--another country where minimal regulations on consumer loans have led banks to lend recklessly--could ripple throughout Latin America, of which Mexico's is the second-largest economy. For decades America has relied upon the rest of the world to finance its consumption. But rising amounts of personal debt in foreign countries, combined with a dimming view of the American economy, could put a damper on this trend. As foreign banks and other lending institutions--which do not enjoy the American luxury of being able to sustain their problems by tapping into pools of foreign investments--slash their capital base due to consumer debt, they may reduce their holdings in the United States. Of course, foreign institutions are not going to just stop investing in America, but even marginal reductions in their investments could have a serious impact on the American economy. Indeed, the pullout has already begun. Foreign direct investment into the United States fell from $301 billion in 2000 to $124 billion in 2001, the most recent year for which comprehensive data are available. And foreign investors have slashed their net purchases of U.S. treasuries, greenbacks, and corporate bonds over the past year--corporate bond purchases fell by a whopping 60 percent in September 2002 from a year before. If foreign money continues pulling out of the United States, leading economists warn, America's debt and current-account deficits might no longer be sustainable, leading to a dollar crash and deep damage to the American economy. "At some point, probably relatively soon, as foreigners pull out their capital, the current-account deficit just won't be able to be maintained anymore," says Robert E. Scott, head of research at the Economic Policy Institute, a leading liberal D.C. think-tank. In a comprehensive research report, Scott's EPI colleagues conclude that the current-account deficit will soon become unsustainable, the dollar will begin to weaken, and the United States will be forced to address this imbalance in trade by moving away from the strong dollar policy which has been a hallmark of both the Clinton and Bush administrations and allowing the dollar to weaken, thereby accepting a deflation in Americans' real incomes. The EPI economists conclude that bringing the current account deficit into balance would require a 10-percent drop in America's GDP. And EPI is hardly the only organization making these claims. Last fall, Stephen Roach, chief economist at Morgan Stanley and one of the most thoughtful, long-term predictors of the world economy, warned clients in a research note that "America's ever-widening current account deficit is on an inherently unstable path." A long-term slowdown of economic growth in the United States could have pervasive effects around the globe. First, American consumer consumption would almost certainly slacken, as Americans began to save more to pay off higher domestic financing. That drop in consumer spending might then further depress global economic growth. Without the uber-consumer nation running at full speed, years might go by before the world economy escaped the cycle of weak consumption and slow growth. Despite increased consumer spending throughout the developing world, Asian countries like Thailand, Malaysia, and South Korea still depend on exports for as much as 50 percent of their gross domestic product. For these states, as well as for most developing countries in Latin America, the United States is by far the largest market. Similarly, China has built up the largest trade deficit with the United States of any country in the world. A falling dollar, which would make exporting to the United States less profitable, would only compound foreign companies' problems. Cutting Cards The consumer-credit problem has not yet developed into a full-blown crisis. Most Asian, Latin American, and European nations have not yet reached American levels of consumer indebtedness and low savings rates. Foreign banks and other lending institutions still possess pools of liquid capital to invest in the United States, keeping America's current account deficit afloat. There is still time for governments, international financial institutions, credit card companies, banks, and other lenders to work together to prevent a global consumer debt crisis. But, in order to give the developing world the benefits of the consumer credit revolution America has enjoyed and protect developing nations from the potentially destructive impact of unleashing easy credit, countries, banks, and credit card issuers around the globe need to be subjected to stricter rules on lending. In short, they need the type of laws we have here in the United States. Nations could impose age limits and minimum income standards for applying for credit cards--a policy Singapore, among some other countries, has already adopted. They could also force credit card companies to charge reasonable interest rates and to use transparent advertising. The United States and other developed countries could work with developing countries to implement internationally recognized credit-evaluation procedures and crack down on banks that continue offering easy credit while defaults and delinquencies soar. Unfortunately, such changes don't appear likely. Neither the United States nor the European Union has shown much willingness to police credit card companies and other lending institutions, let alone teach developing nations to police consumer-lending markets in their own countries. The world's financial media have largely ignored the consumer debt problem as they have focused primarily on the admittedly sexier topic of corporate fraud and bankruptcy. Meanwhile, consumers in the developing world just keep charging and charging and charging ... JOSHUA KURLANTZICK is the foreign editor of The New Republic. COPYRIGHT 2003 Washington Monthly Company Kurlantzick, Joshua Divide and conquer: how breaking up big high schools can be the key to successful education reform. Clinton's war: what Kosovo can teach us now. International aspects International economic relations Blindsided by Asia. Too Secret Code. Credit Cards Debt for Life? Counterpoint: Japan's woes far from over. Beat the clock: with elections around the corner, Peru's Toledo needs big trade deals--and growth--now. Waiting game: Mexico depends more than ever on the U.S. economy. That's both good news and bad. What condo buyers need to know: do you take American Express?
I have butterflies of excitement in my tummy as I welcome you to my Rheumatoid Recovery blog! I am so glad you have dropped by and I can't wait to share with you the incredible journey of healing and discovery that I have been on for the last 23 years! I have learnt so much and had times of immense struggle. I am not out of the woods yet but certainly have made huge improvements in my health and well-being. I really know from experience, how frustrating and isolating having an autoimmune disease can be. If that is happening for you currently, I truly empathise with your suffering. It is my desire that this blog will help many along the path but if it even helps just one person in their healing journey then I will be content.
Love at first sight can happen. The rubbery quiver in her legs. He walked in the door so casually. His aura warm and inviting. Her soul reached for his. of despair, the agony of need. I was hungry for one soft word. days slide by, time is wasted. the way you help me through. the way you fill my needs. rich in love with you.
Home | About ISA100 Wireless | Why IPv6? Why does IPv6 in ISA100 Wireless matter? Internet of Things (IOT), Internet of Everything (IOE), Industrial Internet of Things (I2OT) - whatever your name for it, IPv6 in ISA100 Wireless make the Industrial Internet of Things a reality today. ISA100 Wireless is the only industrial wireless protocol standard to incorporate IPv6 directly as part of its network layer and transport layer. This gives ISA100 Wireless the advantage of seamless end-to-end routing with "anything anywhere" effectively in a single environment. IPv6 in ISA100 Wireless supports multiple subnets which enables sensors to be grouped together much like a VLAN for traffic and network management, while also breaking the network into zones for security reasons. Support for subnet-level mesh, as well as backbone-level routing, is also supported in ISA100 Wireless. IPv6 networks use familiar standards-based addressing and can be managed using tools derived from traditional IT network management tools and systems. Today's generation of network managers and automation engineers understand IPv6 and so will future generations. Security Boost – Internet Protocol Security (IPsec), a major design improvement of IPv6, authenticates and encrypts each IP packet of a communication session. IPsec operates in the Internet Layer, thus it protects any and all application traffic across an IP network. Support For New Services - By eliminating Network Address Translation (NAT), true end-to-end connectivity at the IP layer is restored, enabling new and valuable services. Peer-to-peer networks are easier to create and maintain, more robust Quality of Service (QoS). More Efficient Routing - reduced routing table sizes, more hierarchical routing.
Counting Down to Worlds You are here: Home / Counting Down to Worlds Categories: Featured YuGiOh! Articles, Free Articles, YuGiOh! by Mike Steinman As I write this 2 weeks stand between Team USA and the rest of the World at the World Championships. Just 12 days left before we leave, that's it. Without broken TCG exclusives or OCG cards in the meta there are so many playable decks. If you thought the current format had too many playable decks, preparing for Worlds would quickly make you appreciate how limiting the TCG format is. At Worlds, the possibilities are endless .. Heroes (Standard and A Hero Lives), Inzektors, Dragons, Hieratics, Dark World, Six Samurai, Karakuri, Final Countdown, etc. The list goes on and on. In this article I want to discuss which decks we've found to be insufficient at handling the meta, and why these decks will fail their pilots. I'll start with the deck that is the most fitting for this article's title: Final Countdown. Final Countdown - When I ask people what they think I should play at worlds this is probably the most common answer I get. At first, it seemed like a good idea. It beats Inzektors, Heroes, Dragons, Hieratics, and mostly anything else. But there are a couple problems with it even on the surface. Tour Guide not being in the format boosts Six Samurai's playability a ton; no easy access to Leviathan and Zenmaines is huge. Dark World is also a deck (albeit a bad, inconsistent one) and if they hold their draw cards and Card Destruction til the last turns of Countdown, they can easily deck you out unless everything goes your way. For that to happen you need to have had an early Countdown and not needed to use your draw cards or Gold Sarcophagus to avoid thinning your deck. You usually just resolve a Hope for Escape in this matchup to get extra stalls when you need it instead of using your Jars/Legacies/Upstarts to really thin your deck more than needed, but if all you're drawing are those cards and no Hope in sight you're going to have to use them. You can use Sarcophagus to dig for Escape.. it's not a horrid matchup but winning it relies on a lot of factors that are out your control. And then g2 when they bring in Eradicator Epidemic Virus your odds get even worse. Rounds at the World Championship are 60 minutes, so it's a lot harder to do the whole win g1 with Countdown, lose g2 to their side cards but drag it out to time and win in game 3 because of your sided Burn and LP cards. With the new 60 minute rounds, side cards actually hurt you and a lot of matchups actually become just straight out unwinnable. When you look deeper into the decks interaction with the format, you start to see even more problems. The Hero Lives deck that won the World Championship 2012 Japanese Representative Finals is a horrid matchup. It plays a whopping 4 ways to cut its LP in half (3 A Hero Lives + Solemn Judgment) and an unimaginable 9 ways to "End phase MST you" (3 Mystical Space Typhoon + 3 Gemini Spark + 3 Call of the Haunted on Stratos). I've won games against it but I always had to have triple Scarecrow and the perfect combination of cards to beat it, while they drew minimal amounts of those cards (around 3-4). Inzektor is another iffy matchup. Yes, I just said Inzektors were iffy for Final Countdown. You can never safely double set vs the deck if you're reading an end phase MST because they can just pop whatever they want on their turn. Even then the matchup isn't even that bad. It gets hard where some players are teching 2-3 copies of Raigeki Break or Phoenix Wing Wind Blast. Those cards gain a lot of value in a format without Rabbit and I fully expect people to take full advantage of those game-breaking cards. If not in the mainboard, sided along with multiple copies of Dust Tornado. Inzektor players are going to be fully prepared for Hero and Final Countdown decks and there isn't really much a Countdown player can do about it, especially if they can't even guarantee game 1 anymore. Even Dragon players are getting smarter about beating Countdown. At the NAWCQ, scooping game 1 as soon as you see that they're playing Countdown to save time was a common strategy. Wanting to use all the time in the round they could to play a control game with LADDs, Royal Decrees, Plaguespreader, Catapult Turtle and more was a very smart way to handle the matchup. But now, some Dragon players are even electing to play out game 1s and maining to beat Countdown. Dragons, the easiest matchup before.. suddenly becomes a lot harder. Tournament results prove this shift in thinking and deckbuilding; Oliver Parle, who won the Oceanic Championship with Chaos Dragons use Blood Mefist in his extra deck - a card that is widely obtainable to those attending the World Championship. I've even seen people extra decking T.G. Hyper Librarian as a way to go into Tempest Magician with a 4 star monster and double Effect Veiler. With all the options available to Chaos Dragon players, I can't see them not taking fondly to at least a couple of them and that will spell a loss to you if you're playing Countdown. Six Samurai and Karakuri both being revelent decks is also a huge blow to the deck. Before, you would either: A) side in Lava Golems and Metaion, the Timelords and try to beat them, B) Just take the loss and move on because you probably wouldn't face more than one, or C) Try to stall out as much as possible and tie the game, the latter only an option if you're that kind of player. A is just a terrible way to play the matchup in my opinion, B is completely false in this meta and C doesn't even exist thanks to the 60 minute time limit. Coming to this conclusion was where I pushed the deck to the side and realized I couldn't run it, there was just no way I was going to get lucky enough. Six Samurai and Karakuri are probably weak enough decks that they won't make the top cut and then you'd be home free, and when you look at the probabilities it seems fine that you'd only play 1 in swiss. Just take the loss and move on, right? Even if there weren't other things to be worried about like Dark World, AHL Heroes, Inzektors, etc.. I still don't think I'd take that risk. Losing to an early Samurai or Karakuri puts you in the x-1 bracket where you're likely to face another. If brackets didn't work like that and you just faced 5 random opponents it would be fine, but sadly for the Countdown players Yugioh doesn't work like that. But speaking of those 2 decks, I want to talk about them next. Six Samurai and Karakuri (aka the "Protect the Naturia Beast" decks) - There's no denying it, Naturia Beast is an absolute tank in this format. Getting it onto the field early can spell doom for Heroes, Countdown, Dark World, Hieratics, Inzektors (When it's protecting your Fiendish Chains and Solemn Warnings) and even the Samurai and Karakuri decks themselves. It's the card of the format, it's natural for people to try to play a deck that can consistently churn it out turn 1 and abuse it. Another thing about these 2 decks, their side deck options are almost limitless. Macro Cosmos, Rivalry of the Warlords and Gozen Match, Shadow and Light - Imprisoning Mirrors, and many more are all completely viable options for them. They even have access to other powerful synchros. Let me tell you how powerful those side decked cards are when they're also being protected by a Stardust - It's insane. But the major downfall of these decks comes with one simple word: Consistency. I don't have to tell you how Six Samurai draws sometimes. Sometimes it goes off with Gateway, United and Shi En and all is good in the world, but when deck's good hands are really good, often times their bad hands are really bad. Not to mention, if you don't even open with a turn 1 Shi En what is your deck even doing? The answer is nothing. If you can't consistently get to Kagemusha when you need it, you're playing a Warrior Toolbox deck with cool special summon tricks and a Rank 3/4 toolbox. That doesn't sound like a competitive deck at all in my opinion and if you can't get something rolling within the first couple turns then your deck just falls apart. Not to mention how hard it gets to actually go off when you go second. When your opponents can actually hit your Uniteds and Gateways with their Typhoons, Torrential your boards, and hit your synchros with Solemn Warning. And that's if you even get those really good hands with the deck. Karakuri is also like that but to a much lesser extent. If you do happen to open with an awkward hand that doesn't really have a way to explode you can atleast set a Karakuri Soldier "Nisamu" or try to search your deck for a Komachi via your Merchants and try to get something going next turn. But the deck loses really hard to cards like Effect Veiler, Fiendish Chain and Solemn Warning. Investing 2 cards into a synchro that can be taken down with a single card isn't the best thing, and when your deck forces you to either make those trades or not make plays at all you can often get stuck with the short end of the stick. Karakuri and Samurai both have bad matchups against Inzektor too unless they draw enough Effect Veilers and access to Naturia Landoise+Spell cards. Passing with a field of Bureido, Burei and Naturia Beast isn't very threatening to a player holding an Inzektor Dragonfly. You have to hit hard and fast against Inzektor if you're playing either of these decks and when you consider the fact that sometimes you just open with those hands where you can't make any really spectacular plays, you're just asking to lose to what is considered the most popular deck for the event. When you dive into sidedecks, you also realize that people have side cards for your strategy that they aren't even siding specifically for you. Kinetic Soldier, Fossil Dyna Pachycephalo, Chain Disappearance, and more all already near side deck staples to beat the expected top decks, and they all serve roles in the side deck other than beating your strategy. But it's nice to know that they're also extra cards your opponents can side in to help beat you too! I don't think I could ever play inconsistent decks like these at such a high-level event like Worlds. When you think about it you need only win 4 rounds on Day 1 and 3 on Day 2 to win the whole thing and become a World Champion. That's only 7 rounds; why wouldn't you try to play the most consistent deck? These decks are far from the consistency I'm looking for, and I really don't know why anyone would play either of them. Now onto the last deck I want to talk about in this article, and I'm sure it was the most predictable one.. Dark World - I think this is a terrible deck choice for worlds, yet I keep seeing discussion over it. The fact that I couldn't even find enough good cards to run in DW in the current format, even with Upstarts, means that I'll definitely be playing a lot more of those sub par filler cards with the loss of Tour Guide from the Underworld. Cards like DDV, Mind Crush, Skill Drain, Starlight Road, Dark Smog, etc are all terrible cards to main in DW in my opinion but I'm always forced to do it anyways because there are simply no better options. Which brings me to another point. While we're talking about Skill Drain, I wanted to go over the fact that I don't understand why it's such a huge maindecked card in this archetype. I don't understand how turbo'ing to it can even be considered a win condition. When you're playing something like DW where most of your cards are chainable, no one is going to randomly Space your backrows. In fact, the only real target for your opponent's Space Typhoons are your Gate field spells. By running Skill Drain you're giving them more targets. This means your Drains will hardly ever stick around to do anything or effect the game at all. Moving onto the matchups, it has a pretty good one against Heroes. It doesn't have an easy Zenmaines drop anymore but as long as your opponent doesn't see enough Bottomlesses and Prisons, or if you're able to just pop them with your Graphas, you should be winning against them every time. Inzektor on the other hand is a whole different story. Your own Dealings essentially set up their grave with Hornet/Ladybug while letting them dig for Dragonflies and Centipedes. You might be able to knock a couple out with Dragged Downs but they're still drawing 2 after you see their hand. Oftentimes if they draw an Inzektor name off the top that you aren't prepared for you'll lose or at least be put in a bad position. But how can you even prepare for it? I already covered why I think Skill Drain is bad, I think the only way to guarantee that they can't go off on you is turbo'ing through your deck to Deck Devastation Virus + Mind Crush. That way you can literally rid them of all Inzektors they could possibly have. That still leaves Monster Reborn and Call of the Haunted though! So even if you're lucky enough to do that with a deck as inconsistent as DW, you still can't guarantee your field not getting popped. A turn 1 Naturia Beast also spells doom for this deck. After siding it gets even harder; one landed Dimensional Fissure, Macro Cosmos, or Shadow-Imprisoning Mirror and you're just sitting there until you're able to draw an answer. At which point it's probably too late.. the terrible inconsistency issues, so-so matchups, and huge weakness to single side deck cards turns me off from this deck completely. There's almost no possible way for this deck to go 7-1 in the Worlds environment. While I don't know what I'm playing yet I can tell you one thing; whatever it is, it wont be any of the decks I've listed above. And I don't expect anyone else trying to win Worlds to play them either. I'm sure the decks will be there but they won't win, I can almost guarantee you that. Worlds is such a hard format to predict, Tyler and I often joke about how much easier it'd be to prepare for a YCS. Team USA has been testing extensively and they definitely won't stop anytime soon! I know I certainly haven't gone at bed at a decent time since before the NAWCQ and I definitely miss the pleasure of going to sleep while it's still dark out. But all the testing is worth it - We feel like a have a firm grasp on what's going on and a lot of us feel like we're way ahead of the competition, myself included. The next article I write will probably be the last one before Worlds, but Tyler and I will make sure to keep you guys updated on how it goes! Until next time! - Mike Steinman Mike Steinman Latest posts by Mike Steinman (see all) Thoughts and Tech for the Weekend - May 8, 2013 8-1 (Almost Undefeated!) First Place Des Moines Regional Report - May 3, 2013 Mike Steinman: New Threats, Old Solutions - April 24, 2013 "What deck are you playing for worlds Tyler?!?" – A taste of the World Championship September Banlist Discussion
grande wrote: So, I generally don't think we need to have a team full of Canadians to appeal to Canadians (that's been shown so far), but it's still kind of disappointing that they've loaned one of the few Canadians (Quinn Ngawati) to the Skolars. The reason for this is to get him game time and help him develop. You need to remember the kid hasn't even turned 19 yet and he is a long term project player for the Wolfpack. This will get him up to speed and prepare him for the inevitable step up in class. He is 18 years old and is 6'4, 220lbs. I watched him in a few games last year and he didn't look out of place, he will be a force to reckoned with in a few years. As for Canadian players, rumour is the Wolfpack will be holding open tryouts in Canada. What I've read is this will happen maybe after the end of this season. I've also heard from a good source that they are potentially on the verge of signing a Rugby Union crossover athlete. Arygle shared a pint with some fans at the game in Sheffield and he wouldn't say who it was but dropped that tidbit. It might be a National team player from Rugby Canada, DTH is leaving Newcastle and was rumoured to be heading back to Glasgow but I've read he is looking at retirement and maybe the Wolfpack hauled out the check book? I know they have very deep pockets. This is just speculation on my part but I know for a fact attracting high calibre Union players is going to be part of their strategy going forward. Watching Toulouse Olympique vs Toronto Wolfpack this morning. Excellent game and advert for the sport. Good crowd as well. The RFL needs to expand Super League and get some of these clubs in there. Highlights from Toulouse vs Toronto. It was an outstanding match. Other news, Quinn Ngawati has started the past three games for London Skolars and has apparently played very well. He is looking to be a long term player for the Wolfpack. For those who like me weren't able to watch the video from CBC. Couple of pics I took at the Toronto Wolfpack vs London Broncos match this weekend. Attendance was 7400. West Stand was close to full and East Stand was about 70% filled. The Craft Beer Garden is awesome. Lower bowl in Denver looks pretty sparse to me. It's such a massive stadium though god only knows how many people that is. Anywhere from 10-20k? sk 88 wrote: Lower bowl in Denver looks pretty sparse to me. Considering going to watch Toronto Wolfpack play Halifax RLFC tomorrow at The Shay. Let's see, because I'm not sure they have judged the situation properly. Due to political climate in Catalunya their Challenge Cup win has been heavily publicised, but I doubt it would attract a decent looking crowd. XIII almost doesn't exist there, Barça has a XV team... If they really wanted to play in Barcelona I'd go to Montjuïc. Even Montilivi in Girona, as USAP was considering, is a wiser choice: closer to Perpignan, more pro-independence, better scaled venue. But I get it hasn't got the same appeal. It's a bit of everything. Barça inviting Dragons Catalans without really knowing what rugby league can really attract as a crowd, just of the sake of Catalan fraternity, and rugby league jumping onto any fake expansion opportunity because they think they are on the same footing as union. Toronto Wolfpack leading Leeds Rhinos 12-10 at HT. Spain v Russia this saturday in Valencia, 15.00 CET. It's part of the Euro B championship and of the RLWC qualifying. Euro B is a pool of three teams (Spa, Rus, Serbia), the best two of which will proceed to next level: a 6-teams competition with Italy, the worst two nations of Euro Championship A (Fra, Ire, Wal, Sco) and the winner of Euro Championship C (Greece or Norway). The best four of these six nations qualify to the World Cup. Red Star Belgrade are looking to join the UK leagues. I've been saying it for years but multi-sports clubs are the best way to expand into new markets, in Europe in particular. They draw in casual fans in a way that unknown brands do not. It will be interesting to see what happens with Penarol and Nacional in Uruguayan RU. 4N wrote: Red Star Belgrade are looking to join the UK leagues. I've been saying it for years but multi-sports clubs are the best way to expand into new markets, in Europe in particular. They draw in casual fans in a way that unknown brands do not. So they classic RL questions arises: how many of those players are not Ozzies? Because rugby is viewed as an old/declining sport in Romania. Steaua were better 30 years ago than they are now. Where were Steaua's big rugby crowds 30 years ago? FC Barcelona has rugby too. Where are their big crowds for their rugby club? Big crowd in Toronto today against London. Lamport is basically full and there is a big buzz around the Wolfpack in the city. Almost a 10k crowd. RL is here to stay in Toronto. 4N wrote: Almost a 10k crowd. RL is here to stay in Toronto. Unlucky loss, 4-2 in what was an excellent match. Super League has a London side again and Toronto will be chasing again next year.
'Hours-Old' Newborn Left Abandoned On Porch With Umbilical Cord Still Attached Photo by ADEK BERRY/AFP/Getty Image Lexi Lonas Contributor A newborn baby, only hours-old, with the umbilical cord still attached was found abandoned Tuesday on a porch in Darby, Pennsylvania in 93 degree weather. Terrell Phillips found the baby on his neighbor's porch wrapped in a blanket, 6abc reported. "I picked it up and as I picked it up the towel was unraveling and I saw the baby still had the umbilical cord on it," Phillips told 6abc. "He said, 'Mr. Tom what is this?' And he says there's a baby here," Tom Dailey, Phillip's neighbor whose porch the baby was abandoned on, said about the event. Whenever the little girl started crying, Dailey picked her up, saying "it felt good" since both his kids are grown that he still remembered a thing or two. Phillips called the police and the baby girl was taken to the hospital. Police say the newborn is doing well. (RELATED: Baby Girl Rescued After Police Found Her In A Plastic Bag On The Side Of The Road) Now, the Upper Darby Police Department is searching for the parents. "Mom, if you're reading this, call us," their Twitter post says. This adorable hours old newborn was left abandoned, alone, in the 100 blk Englewood today. WE NEED HELP locating the parents to get them the assistance that they need. Mom, if you're reading this, call us. Call us at 610-734-7693 with tips or email [email protected] pic.twitter.com/b0dmXyULT7 — Upper Darby Police (@UDPolice) July 30, 2019 The police do not know where the little girl was born or who left her on the porch; however, the community is rallying behind the little one. "Probably 98-percent of the phone calls that we're getting are people who want to adopt the baby," Upper Darby Police Superintendent Michael Chitwood said. The baby was left on a porch less than half a mile away from both a fire station and police department. "If somebody wants to drop off a child to a hospital or police station, as long as it's not hurt and less than 28 days, you can do it without any criminality," Chitwood said. Tags : baby pennsylvania police Lexi Lonas
John M. Petruzzi, Attorney at Law Call Now to Schedule A Free Consultation (713) 581-1789 Houston Bill proposes to alter Texas sex offender registry Need Help? Don't Wait! Brief case description On behalf of John Petruzzi of John M. Petruzzi, Attorney at Law posted in Sex Crimes on Thursday, May 30, 2013. Many Texas readers probably know that Texas has a reputation for being tough on crime. However, the Texas legislature this session has been making some valiant efforts to reverse these possible injustices by enacting laws in order to protect individuals facing the death penalty, as well as laws to help some to find work after completing a sentence. For example, a sex crime charge often causes much strife for those convicted of the crime. In the state of Texas, there are not only fines and jail time potential consequences, but also serious damage to reputation that can heavily impact one's future. As in many states, Texas publishes a sex offender registry which requires all sex offense convictions to be available to the public. This policy, while helpful in some ways, has also made it substantially more difficult for individuals to re-enter society post sentence by obtaining a place to live and a job. This is a serious problem where individuals who attempt to transition back into society face backlash when trying to rent an apartment or obtain a paying position because landlords and employers run from the sex offender registry. The Texas Association of Business is working to put a stop to this problem by lobbying the Texas legislature to make information about where an offender is employed available only to law enforcement. This effort would provide more incentive for employers to hire previously convicted offenders as they would no longer face drops in business for having a convicted offender on the payroll. Some argue the change would strip the public of valuable safety information, yet the bill recently passed the House and Senate and is on the way for the governor to sign. Source: The Texas Tribune, "Business Group Helps Criminal Justice Bills Pass," Maurice Chammah, May 23, 2013. Tags: damage to reputation, sex offender registry Related Posts: Former Texas judge indicted for sexual assault, Being accused of a sex crime in Texas can have damaging effects, School psychologist accused of sex crime, Sexual assault accusation on Texas A&M Campus theft & property crimes (16) How do you know you are getting a fair trial? Home search results in multiple arrests for alleged drug crimes Texas student charged with multiple violent crimes Violent crimes: Teen charged with assault Follow @@JMPetruzziLaw We serve clients in Houston, Texas, and the surrounding areas, including Harris County, Galveston County, Brazoria County, Fort Bend County, Montgomery County, Chambers County, Jefferson County, Polk County, Houston, Clear Lake, League City, Friendswood, Texas City, Galveston, Sugar Land, Richmond, Rosenberg, Pearland, Angleton, The Woodlands, Conroe, Spring, Humble, Kingwood, Katy, Baytown, Deer Park, Pasadena, Beaumont and Bellaire. © 2020 by John M. Petruzzi, Attorney at Law. All rights reserved. Disclaimer
IL-76TD EMERCOM of Russia took part in the... | OJSC "Ilyushin Aviation Complex" Large-scale demonstration exercise was held on May 17, 2016 at the Noginsk rescue center (Moscow reg.). One of the most exciting episodes of the exercise was the use of Il-76TD EMERCOM of Russia to demonstrate the abilities to fight forest fires. Il-76TD developed by "Ilyushin Aviation Complex" demonstrated ability to extinguish fires from the air with the use of WPA-2 spray tanks. Two WPA-2 tanks installed onboard Il-76 aircraft can accommodate a total of 42,000 liters of water or fire extinguishing fluid. During final part of the exercise, Il-76TD took part in the air parade which included all the aviation units involved in the exercise. Il aircraft is the main fire-fighting aircraft in Russia. Now they are used to extinguish wildfires in the Siberian Federal District and helped to defend several settlements against fire in the Republic of Buryatia and the Trans-Baikal Territory.
The European Union has imposed sanctions on Syria's Al-Dounia TV channel. The decision has provoked a strong response from Lebanon's Al Manar TV, itself often criticised for its lack of balance in its broadcasting. Europeans are forbidden to do business with the Syrian channel, along with similar proscriptions against Syria's largest cellular operator (Syriatel) and some construction and investment companies, each with close links to the Syrian regime.
Läroverket för gossar och flickor, (eng. The educational institution for boys and girls) also known as Brobergska samskolan or Broban, was a Swedish school that operated in Helsinki 1883–1973. The school was the first co-educational school in Finland. The author and artist Tove Jansson, creator of Moomin, went to Läroverket för gossar och flickor. History Läroverket för gossar och flickor was founded in 1883 by Professor Fridolf Gustafsson, assessor Uno Kurtén and assisting professorin Georg Asp. The school was originally called Helsingfors lärovärk för gossar och flickor, but the name was officially changed to Läroverket för gossar och flickor in 1912. Karl Theodor Broberg was headmaster 1883–1900, and the school was unofficially called Brobergska skolan (eng. Broberg's school) or "Broban" after him. Läroverket för gossar och flickor offered nine educational levels, and from 1889 the students could complete the matriculation examination and thereby qualify for entry into university. The school therefore broke new ground, since this opened the door for girls to graduate and continue their studies at a university. The school followed a curriculum with special emphasis until the Russification of Finland (1899-1905) when all school curricula were aligned. The school operated at various addresses in central Helsinki until 1895, when it moved in to its own building at Korkeavuorenkatu 23, where the Design Museum is now located. In 1973, Läroverket för gossar och flickor merged with Laguska skolan and formed Minervaskolan. In 1975, the new school was merged with Tölö Svenska samskola (Zillen) and closed two years later when the Finnish school system was reformed in 1977. The pupils were moved to Lönnbäckska skolan and Lönnbäckska gymnasiet. Famous alumni Emil Fabritius, architect and sports shooter Greta Hällfors-Sipilä, artist Tove Jansson, author, illustrator, artist Viktor Jansson, sculptor Ruben Lagus, military, general major Tor Nessling, industrialist Gunnar Nordström, physicist Michael Widenius, software programmer Headmasters 1883-1900 Karl Theodor Broberg 1900-1905 J.M. Granit 1905-1917 Jakob Einar Meinander 1917-1925 Rolf Krogerus 1925-1944 Fritiof Freudenthal 1944-1947 Torsten Steinby 1947-1968 Eric W. Nyström 1968-1973 Hilding August Karling 1973-1977 Margareta Grigorkoff (after the merger with other schools) References Educational institutions disestablished in 1973 Educational institutions established in 1883 Schools in Helsinki 1883 establishments in the Russian Empire Tove Jansson Swedish-speaking population of Finland
Articles, Featured, Features, Headline September 10, 2021 Eve Of Darkness Book Explores Toronto's Heavy Metal Scene From 1980-1989 Saturday, September 25th will make the launch of a very important artifact chronicling the history of the heavy metal music scene in the greater Toronto, Ontario area. On that day, UXB Press will be releasing their newest book, entitled Eve Of Darkness: Toronto Metal in the '80s. This book is a massive, painstakingly put together tome dedicated to the city's burgeoning heavy scene during its heyday. Reviews - Audio July 19, 2018 Fu Manchu – Clone of the Universe In an ever-changing universe, one thing that is pleasingly consistent is a new Fu Manchu album; it is as though this album was always… Reviews - Classics, Reviews - Vinyl February 22, 2016 Rush – Grace Under Pressure LP Perhaps the most important thing that Rush proved when they released Grace Under Pressure is that (to paraphrase what George Orwell wrote in 1984)… Reviews - Classics, Reviews - Vinyl December 9, 2015 Rush – Signals LP Just one year after they began to challenge both themselves and their audience with new songwriting ideas and compositional presentations on Moving Pictures, Rush… Reviews - Classics, Reviews - Vinyl November 26, 2015 Rush – Moving Pictures LP It is often regarded as an inconvenient truth, but the fact is that it becomes increasingly difficult for a band to change or take… Features, Staff Picks June 30, 2014 Canada Day 2014: Best Canadian metal from years ending in '4… As Canada Day rolls around again, some of our regular Hellbound contributors have pitched in for another year of celebrating Canadian metal on the… Reviews - Audio May 15, 2014 Cynic – Kindly Bent to Free Us Around the late '60s, progressive rock was born. Those who adopted the infant genre went forth from England, blew minds, and progressed, taking the… Featured, Reviews, Reviews - Audio February 7, 2014 Cokegoat – Vessel By Gruesome Greg Truth be told, I was drawn to this Chicago sextet by their bizarre moniker, along with the promise there was doom… Headline, Reviews, Reviews - Live September 20, 2013 Blood Ceremony / Biblical / Cauchemar @ Horseshoe Tavern, Toronto ON, September 14, 2013 "A smoke-filled backdrop and a barefoot bassist set the stage for vocalist/flautist/keyboardist Alia O'Brien to cast a spell over the crowd. Her seemingly effortless weaving between instruments, combined with undeniable natural charisma, made her a magnetic presence on stage." Danielle Griscti reviews the Toronto album release party by Blood Ceremony at the Horseshoe Tavern on Saturday, September 14th, which also featured Biblical and Cauchemar. Whoa, talk about a blast from the past… In case you didn't know, Moxy had a few hits in the mid-to-late 70's. Their 1975 self-titled album kinda sounds like Rush's debut, before the latter got more progressive, and featured guitar virtuoso Tommy Bolin on several solos–he just happened to be recording in the studio next door. These guys were so big down in Texas that AC/DC opened for them on a string of dates in 1977, and were reportedly dubbed the Canadian Zeppelin by Sounds critic Geoff Barton…
10 Department of Education and Training International Education Division GPO Box 4367 Melbourne Victoria 3001 Australia Tel: +61 3 9637 2990 Fax: +61 3 9637 2184 Email: [email protected] Web: www.study.vic.gov.au CRICOS Provider Code: 00861K Make an application Students may make an application to study in Victoria at their school of choice. Accredited education agents and students and their families can apply online at www.study.vic.gov.au Information about study in Victorian government schools is also available from these online resources: Study Victoria www.study.vic.gov.au Victorian School of Languages www.vsl.vic.edu.au Victorian Certificate of Education www.vcaa.vic.edu.au/vce/studies/index.html Select Entry Accelerated Learning www.education.vic.gov.au Join us Connect with our online community of current and future international students on Facebook at www.facebook. com/InternationalSchoolStudentsVictoria and on WeChat at StudyMelbourne. Taking the next step More information about education services provided to international students is available from the International Education Division of the Department of Education and Training.
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When ASRA Pain Medicine discloses your personal information to its agents or subcontractors for these purposes, the agent or subcontractor in question will be obligated to use that personal information in accordance with the terms of this privacy statement. In addition to the disclosures reasonably necessary for the purposes identified above, ASRA Pain Medicine may disclose your personal information to the extent that it is required to do so by law; in connection with any legal proceedings or prospective legal proceedings; and in order to establish, exercise, or defend its legal rights. ASRA Pain Medicine will take reasonable technical and organizational precautions to prevent the loss, misuse, or alteration of your personal information. All the personal information you provide will be stored on secure servers. Information relating to electronic transactions entered into via this website will be protected by encryption technology. Information that ASRA Pain Medicine collects may be stored, processed, and transferred between any of the countries in which ASRA Pain Medicine operates to enable the use of the information in accordance with this privacy policy. Recognizing that laws vary among countries, ASRA Pain Medicine will, to the best of its ability, conduct all such transactions in accordance with the laws of applicable countries. In addition, personal information that you submit for publication on the website will be published on the internet and may be available around the world. You agree to such cross-border transfers of personal information. Updating this statement ASRA Pain Medicine may update this privacy policy by posting a new version on this website. You should check this page occasionally to ensure you are familiar with any changes. This website contains links to other websites. ASRA Pain Medicine is not responsible for the privacy policies or practices of any third party. Contact ASRA Pain Medicine If you have any questions about this privacy policy or the treatment of your personal information, please contact ASRA Pain Medicine Membership Services at 3 Penn Center West Suite 224 Pittsburgh PA 15276 Tel. +1 412-471-2718 OR +1 855-795-2772 (toll free, U.S. Only) Email: [email protected] In order to help enhance the performance and functionality of the Site, we utilize session, persistent, and third-party "cookies" that store a small piece of data on a users' computers and collect certain information about the users' visit to our Site. We also use cookies to understand users' browsing and buying activities so that we can measure the success of online advertising campaigns we run on the Site. Our Site also uses web beacons (either directly or from our partners), along with cookies, to determine if a user has visited a particular website. 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The Cape Cryptic Carnivore project is a field research study on cryptic carnivores, most notably brown hyenas (Hyaena brunnea), in the Little Karoo in South Africa. The research is led by Elsa Bussière, a PhD student with the ADU at the University of Cape Town. Elsa grew up in France where she completed an MSc in Agricultural Engineering and an MSc in Forest, Agriculture and Environmental Engineering in 2011. Her passion for science and nature took her to Hwange National Park in Zimbabwe where she worked as a field biologist for a large mammal project, led by the French Center of National Scientific Research (CNRS). She then came to SA to do an MSc project with the ADU on statistical ecology, analyzing bird atlas data. During this time, she helped other researchers with their fieldwork on African penguins, weavers and pygmy falcons. Her current work on brown hyenas started in 2014 and forms part of her PhD research. Her thesis is entitled 'Mitigating human-wildlife conflicts and improving statistical tools for mammal monitoring and conservation'. Her area of focus is the Little Karoo, where the last remaining brown hyena population in the Western Cape Province can be found. She ran a massive camera trap survey in 4900km² of rugged Karoo mountains, in the area of Touswriver, Lainsgburg, Barrydale and Montagu. Preliminary results show that the most photographed carnivores in this region are (in descending order): black-back jackal, African wild cat, caracal, brown hyena, leopard, aardwolf and honey badger. Brown hyenas are primarily scavengers. The bulk of their diet consists of carcasses killed by larger predators, and although they may supplement their diet with rodents, insects, eggs, fruit etc, they are poor hunters, and live prey makes up only a small proportion of their diet: Brown hyenas have black and white stripes on the legs and every individual has a unique pattern, making them individually identifiable (similar to leopards). Using this pattern Elsa was able to identify 18 different individuals in the study area. Nine individuals were photographed in the Sanbona Wildlife Reserve, which also has lions and cheetahs providing carrion. The other individuals were found on Anysberg Nature Reserve, small private nature reserves and farmland, where only leopards, jackals and caracals could provide carrion to scavenge. Interestingly, the brown hyenas outside of Sanbona that cannot rely on lions and cheetahs for food, seem to have much larger territories and may also hunt small animals to complement their diet. One adult female was also collared with an iridium satellite collar. She had a home range of roughly 300 km2, and covered at least 900km in a month, sticking mostly to river beds, dry valleys and fence lines. At least one of the identified brown hyenas got caught in a gin trap, which was originally set by a private landowner in order to catch jackals and caracals. The animal unfortunately had to be put down. It is the only confirmed killing, although rumors of other captures on different farms do the rounds. Due to the low number of individuals in the population, human persecution poses a real threat to the survival of the species in the region. Learn more about the Cape Cryptic Carnivore Project on the dedicated project Facebook page.
NSS 2010 will be in technical co-sponsorship with the IEEE and the IEEE Computer Society Technical Committee on Scalable Computing. The publication will be the IEEE Computer Society Proceedings (EI, ISTP, and INSPEC indexed) *. Selected best papers will be published in The Computer Journal (Oxford), Computers & Security (Elsevier), and Concurrency and Computation: Practice & Experience(Wiley). All journals are SCI and EI indexed.
Q: Windows: How to take a Screenshot of a Window programmatically? I'm trying to use Windows APIs to take a screen shot of a window. Here is my current code: //Grab the window HWND window = me;//GetForegroundWindow(); HDC context = GetDC(window); RECT windowRect; GetWindowRect(window, &windowRect); int w = windowRect.right-windowRect.left; int h = windowRect.bottom-windowRect.top; //Copy the data for (int y=0;y<h;y++) for (int x=0;x<w;x++) { COLORREF color = GetPixel(context, x,y); std::cout<<color<<std::endl; } The width and height return correctly (as well as the window location), but the color is always 0xFFFFFF (white). It seems like it should be fairly easy as in windows taking a screenshot of a window is simply alt+shift+Print Screen
Ken Horstman is the senior director of total compensation at the University of Minnesota, one of the largest public research universities in the United States, covering five campuses across the state. He has responsibility for the strategic direction and administration of the University's compensation and classification programs, and employee benefit programs covering retirement, health, wellness, and welfare benefits. The University's self-insured health plan represents over 38,000 enrolled members across Minnesota. Mr. Horstman has over 30 years of experience in the areas of employee benefits, human resources, and operations management. He holds undergraduate and graduate business degrees from the University of Minnesota. He is also certified as an employee benefits specialist (CEBS), and as a senior professional in human resources (SPHR). Ken is a regular Action Group guest blogger, most recently sharing his perspective about his appointment to Board Chair. Click here to view Ken's blog. Jon Born is the senior director of benefits for UNFI, a grocery industry leader, serving customers through a network of over 3,000 owned, franchised and affiliated stores across the country. He is responsible for management of the retirement and health and welfare benefit programs, with combined assets exceeding $4.5B. UNFI's self-insured health plan represents over 16,000 enrolled members nationwide. Mr. Born has over 30 years of experience in employee benefit plan management in the large employer market segment. He is a Certified Employee Benefits Specialist (CEBS), and holds a BA from the University of Minnesota — Morris. To learn more about Jon's viewpoint on the Specialty Drug Learning and Action Network, click here. Nathan Moracco has served as assistant commissioner for Health Care at DHS since December 2013. Prior to his current position, he served as acting deputy assistant commissioner for the Health Care Administration since October 2013. Prior to coming to DHS, Moracco served as director of the Employee Insurance Division within Minnesota Management & Budget for more than a decade. In this role, he managed the State Employee Group Insurance Plan (SEGIP) and the Public Employee Insurance Program (PEIP), an insurance program for local units of government, including cities, counties and K-12 school districts. Mr. Moracco also worked at Honeywell International for seven years prior to his state service. To read about Nathan's commitment to Action Group membership, click here. Nance Lee Mosquera is the employee benefits manager for the City of Saint Paul. In this role, she is responsible for strategic planning and management of employee and retiree health care, wellness and other benefit programs, serving over 3,000 employees. Ms. Mosquera has experience in all sides of health care pricing and management, as a prior director of underwriting at UnitedHealthcare, broker, as well as benefits management. She holds a bachelor of arts degree in communications from Bethel University, serves as a presenter for The Action Group, is on the HR Subcommittee for the Board of Directors at Fraser, and is a member of the Fairview Advisory Council. Jon Schloemer is the director of compensation and benefits for Fleet Farm and is responsible for all aspects of their benefit offerings and the team that delivers them. Fleet Farm has over 6,000 team members in 40 locations. Mr. Schloemer has a bachelor of arts degree in accounting from St. John's University, and is a designated member of the American Society of Pension Professionals and Actuaries (ASPPA). Jon is an outstanding advocate for The Action Group, encouraging his fellow members to get involved and take action. Most recently, he contributed a blog on the high value of The Action Group's Annual Employer Benefits Survey. Deidre Serum is the senior director of employee benefits at Best Buy, a leading multi-channel global retailer and developer of technology products and services with 125,000 employees and over $40B in revenue. She is a responsible for the strategy and design of all employee benefits. She has been with Best Buy since 2009, following a 20-year career at Carlson, the world's leading travel and hospitality company. Ms. Serum holds both Compensation (CCP) and Benefits (CBP) Certifications from World at Work, and she graduated from the University of North Dakota. As an active and involved Action Group Board member, Deidre recently took the lead on blogging about our Member Survey, encouraging colleagues to share their insights about how to continuously improve the member experience. Read more here.
There are currently 176 single family homes for sale in Palos Verdes. There are 70 Palos Verdes single family homes in escrow with accepted offers, and 608 single family home sales recorded YTD in 2017. Low inventory appears to be the New Normal market condition for Palos Verdes as the number of homes for sale has not varied much during the past two years. The single-family home market in Palos Verdes remains a seller's market due to supply (low) and demand (high). If you're considering selling a Palos Verdes property, do not let the approaching holiday season deter you. I showed a new listing Sunday afternoon that came on the market two days earlier. The agent has two offers and talk of more on the way. Remember, the early bird gets the worm, and the same is true for buyers and houses. On the other hand, if you are a buyer and hope to find your dream home in Palos Verdes, you must team up with an agent and be diligent about seeing any strong possibilities as soon as possible.The market has been extremely tight for years, and there is pent-up buyer demand. Homes in good condition and priced right are snapped up within days of hitting the market. Don't forget to have your lender ready to write a preapproval letter, and make sure your down payment is liquid and easily accessible. When a seller is evaluating multiple offers, a qualified buyer often wins out over those who submit an offer without verification of lender approval and down payment source. Preparation is vital when it comes to buying a Palos Verdes home.
Home > Latest News > Prince William Prince William Is No Longer Reluctant About Becoming King, Now Believes 'He Is The Man For The Role,' Claims Expert Jan. 24 2022, Published 10:07 a.m. ET As Prince William grew up, he became more and more worried about having to take the throne one day — but royal expert Jennie Bond believes that he's now comfortable with the idea of leading the country. "I think we did see a reluctance to take on the role earlier on, in his early adolescence, he knew his destiny as none of the rest of us do from such an early age, but in the last couple of years he has shown convincingly that he is the man for the role and that he cares about being king," she spilled to OK! magazine. "He absolutely fully accepts the role and the responsibility destiny has put his way." QUEEN LETIZIA & KING FELIPE VI HAND OUT MEDALS & DIPLOMAS AT THE 16TH ANNUAL GALA OF THE SPANISH OLYMPIC COMMITTEE — PICS After Queen Elizabeth steps down from the position, Prince Charles is next in line, though some believe that he could step back and just let his eldest son take over instead. "Who knows, constitutional law may be rewritten. He [Charles] may not take the throne, he may hand it to his young son," Princess Diana's former vocal coach Stewart Pearce previously told The Daily Star. "He doesn't want to do it, such a difficult task." On the other hand, the Duke of Cambridge has already been thinking of ways that he can change the monarchy and the country for the better. "While he respects protocol, he plans to modernize some aspects and is making it his mission to be more relatable than previous generations," an insider once told Us Weekly. RUFF DAY: KATE MIDDLETON & PRINCE WILLIAM VISIT CLITHEROE COMMUNITY HOSPITAL — AND PLAY WITH SOME CUTE POOCHES! "William accepts that being in the spotlight is part of the job, and is fine with it," continued the insider. "He takes his future role as King and seriously and sees at as a great honor and privilege to be in his position. The Monarchy and his family will always come first."
Benedict Wong Wants Nightmare As Doctor Strange 2's Villain Marvel Fans Petition to Have Brie Larson Replaced as Captain Marvel Parasite Director Bong Joon-Ho Doesn't Want To Direct Marvel Movies Marvel Reveals How Black Widow Escaped in Captain America: Civil War By Tiny Diapana | More Articles We might not know that much about the plot details of Doctor Strange in the Multiverse of Madness aside from the fact that the Phase 5 Marvel movie is going to be "the first scary MCU movie," but it looks like Doctor Strange Wong actor Benedict Wong wants to have a pretty strong demon as the villain of the film's upcoming sequel. ComicBook.com just recently spoke with Wong to talk about his upcoming film Gemini Man and during the interview, the publication tried to ask him a little about the highly anticipated Marvel movie, Doctor Strange Multiverse of Madness. The actor wasn't able to reveal any details, but when asked about what villain he wanted to meet in the series, Wong couldn't help but answer honestly. "I don't really know, to be honest... I think there's Nightmare, isn't there? I don't really know that many to be honest, I just kind of allow it to appear. Whatever happens, I just allow it to happen," the actor revealed. Nightmare is an interesting choice. A recurring villain in the comics, Nightmare usually serves as Doctor Strange and Ghost Rider's villain. The personification of nightmares, the villain is most often called the demon prince of the Dreamscape. Because of his habit of interfering with mortals, Nightmare often comes into conflict with Doctor Strange. The villain would be a perfect fit in Doctor Strange in the Multiverse of Madness which is rumored to incorporate horror elements into the Marvel Cinematic Universe. Doctor Strange in the Multiverse of Madness is set to premiere on May 7, 2021. Read: Captain Marvel's Brie Larson Reveals She Wasn't Actually Aware Of Her Haters Tiny Diapana is a literary dilettante and warrior of the written word. She has a penchant for poetry, with some of her compositions seeing publication in anthologies. Tiny is drawn to magic realism (eg. Salman Rushdie, Etgar Kerret) and books that are stylistic and Kafkaesque. Her free time is often spent on boardgames, books, manga, comics, pop culture series, movies and practicing bass. @Tiny Diapana | [email protected] Black Adam: Dwayne Johnson Shares New Training Photo for DC Film
Merityre Specialists ltd was established in 1963. Located in Andover in Hampshire, the firm has enjoyed considerable success. It operates 19 branches throughout southern England, including several in the Thames Valley. This is Merityre's founded Customer Care programme, which lays down best quality standards for a huge array of activities - from depot presentation through to handling client queries. We strive to supply a huge choice of items at realistic prices, plus a range of special promotions and discount offers.
Q: Paypal REST api - How to control the display language? I'm working on the PayPal REST API with the official PHP SDK: https://github.com/paypal/rest-api-sdk-php However I notice the REST call point me to a check out page (Sandbox mode) in Chinese locale, any idea how to control the display language as English? I found the same question is asked a year before but no answer: REST Api integration - how to force payment page's language? Or either solution are provided base on Classic API, looks like not applicable on REST API: How can I control the language displayed in the Paypal Sandbox? A: There are no LOCALE options you can pass to the REST API, however, if you set the shipping address for the transaction it should update automatically. You can test with the call below. curl -v https://api.sandbox.paypal.com/v1/payments/payment -H 'Content-Type: application/json' -H 'Authorization: Bearer {ACCESS_TOKEN}' \ -d '{ "intent":"sale", "redirect_urls":{ "return_url":"http://localhost", "cancel_url":"http://localhost" }, "payer":{ "payment_method":"paypal" }, "transactions":[ { "amount":{ "total":"7.47", "currency":"USD" }, "item_list":{ "shipping_address":{ "recipient_name":"Test Test", "type":"business", "line1":"187 Alameda Santos", "city":"Sao Paulo", "country_code":"BR", "postal_code":"01119", "state":"Condominio Edificio Platinum" } }, "description":"This is the payment transaction description." } ] }' A: in addition to Aaron answer, you can use ExpressCheckout REST api to set a LOCALE see https://developer.paypal.com/webapps/developer/docs/classic/api/merchant/SetExpressCheckout_API_Operation_NVP/ A: you can pass locale parameter using the PayPal REST APIS as mentioned here - https://developer.paypal.com/docs/api/payments/v1/ Example "application_context":{ "locale":"en_IN", "brand_name":"MY BRAND", "landing_page":"Billing" }
An expansive range of dining options reflects the diversity and variety of our culture. Whether it's a quick cup of coffee or a leisurely meal, you'll find a choice that satisfies your appetite. Bon Appétit Management Company's Arbuckle Dining Pavilion is a destination for food that's alive with flavor and nutrition, prepared from scratch using authentic ingredients. You'll find something to please every palate: sizzling grilled items, artisan flatbreads and pizzas, tossed-to-order salads, daily-changing global cuisine, seasonal soups, and other fresh fare. With indoor and outdoor seating, Arbuckle serves as a natural meeting point and a relaxing spot to take a break. Operated by Coupa Café, TA Associates Café features the finest single estate coffees from Venezuela as well as its popular Spicy Maya and Abuela hot chocolates. Locally grown products are used to create the daily menu featuring soups, salads, Venezuelan arepas, paninis, pastries, and other Coupa specialties. It's a great place to grab a quick latte to go, or join a colleague for a light lunch and leisurely discussion. Beyond Knight Management Center, the greater Stanford campus offers an even wider range of dining options.
League of Legend: Summoner's Rift In every game you play, there will always be a map of which would let you see the way and routes in obtaining your goal. Usually, the games with a very much detailed map are those adventure types or that of which have opponents to battle with. One example of a game that lets you look at its map is the multiplayer online battle arena (MOBA) game named as League of Legends or abbreviated as LoL. What is unique about the game is that its map has its online name - Summoner's Rift. Now to give you an overview of this Summoner's Rift, it is obviously the visible map in LoL. In this map, you could already depict the number of players in both teams since it would give you a picture of two sides where, in each side there is a team consisting of five players. The main goal of the game is to destroy the Nexus, which is known as the base building. This Nexus can be seen from the Summoner's Rift as it is guarded by defensive structures called towers or turrets. There are two opposing Nexus in the Summoner's Rift. One is located on lower left side while the other is at the upper right-hand side. There are also these weak and small creatures that help defend the Nexus and are called minions. They usually move towards the enemy base and are scattered along three sides, which are the top lane, middle lane, and the bottom lane. If you are in-game, usually you would go for fighting over with the minions first as they are naturally weak only and after which, you opt to destroy turrets one by one. In this case, you and your team members must really perform your wherein tactics and strategies as to how you would be able to distract your opponents. As you deal damage with the waves of minions and other nearing foes, you have already the possibility of destroying every turret that comes your way. Hence, it would be easier than for you to sneak and destroy the Nexus of that of your enemy base, which would let you win the match. But wait. There's more! In Summoner's Rift, there are some areas that are designated for your jungle place. In this jungle, there are jungle monsters that provide you with experience or XP and gold that are necessary for enhancing your abilities. There are also these elemental drakes or also known as elder dragon, which gives you with buff that is essential for augmentation of skills. Also, there is Rift Herald that when you get to kill it, it serves as one of your mediums in destroying enemy turrets. Lastly, there is Baron Nashor, which is the most powerful neutral enemy. It gives you buff that makes nearby minions more powerful thus, helping you to get that victory in your hands. In this time and age, there have been already a lot of changes made as the game is not that static to not improve over time. For you to be always updated about its augmentation, sign up now and join the most played MOBA of all time.
BALTIMORE — It is stinkin' hot here in Baltimore. It's about as hot temperature-wise as it was in Florida, but here you feel like you're just wearing the weather. The humidity is unbelievable and this outdoor pressbox is like a sauna. While sitting and chatting with Jays skipper Cito Gaston today, Hall-of-Famer Jim Palmer was standing nearby. Someone asked Gaston if he'd ever had the unfortunate task of trying to hit against Palmer back in the day. "I might've faced him in Spring Training, but he was in the American League all that time and I was in the National League," said Gaston, who then chuckled. "And that was a good thing. I know Gino has faced him…" At that, Gaston called Jays hitting coach Gene Tenace over and pointed to Palmer: "How'd you do against that guy over there?" "Terrible," said Tenace, shaking his head and walking away. "I helped him get to the Hall of Fame." A strange observation from today: inside the Jays clubhouse was a bunch of balloons. The largest was in the shape of a turtle and it read: "Have a speedy recovery." A few of the others had messages like "You're awesome" and "Thinking of you." A note attached had a short poem and finished with the line "We still believe!" No players had a clue who sent the mystery balloons. Oh, actual news? Well, as the Toronto Sun reported today, Mel Queen is back in the Jays organization, working with Minor Leaguers. Jays GM J.P. Ricciardi said, though, that contrary to the report, Queen was not brought back to "evaluate the farm system" and it was also false that Rob Ducey was on deck to be the next farm director. Ricciardi said he helped bring Queen back to give the Jays former pitching coach a chance to work in the game again after being out for so many years. Ricciardi said that the 66-year-old Queen will help with "special projects," working individually with pitchers in the system. That's all there is to it, says the GM. Ricciardi and Gaston also noted that lefty John Parrish will get at least one more turn in the rotation. Ricciardi went on to say that Parrish would be evaluated after his next outing and added that the club wants to get David Purcey up for an extended look at some point this season. at 7:05 p.m. ET at a sweltering Camden Yards Joe Inglett, RF Marco Scutaro, 2B Alex Rios, CF Rod Barajas, C Matt Stairs, DH Adam Lind, LF David Eckstein, SS PITCHING: RHP Jesse Litsch (8-6, 4.16) PITCHING: RHP Radhames Liz (3-2, 7.57) Wow-David Cooper our first round draft choice this year, went 3 for 6 today at Lansing and improved his stats to .400ba/.423 obp/.620 slg/1.064OPS. He's now leading the league in batting average, slugging,OPS and is 3rd in obp. Time to send this kid to Dunedin, it doesn't look like there's any more to prove in A- Lansing. If anyone wants to check out where a number of our prospects are, check Lansing. Take a look at Cooper, Jaspe, Baksh and don't overlook both Ahren and Jackson who are starting to turn it on,coincidentally ever sense Cooper arrived. Lansing won the first half in their league and have the best record. The Lansing team pitching leads the league in era at 2.88 (next closest team is 3.37),innings pitched, least runs given up,least hr's given up, most k's, and are 3rd in whip. Send Litsch back down to the minors and bring up Percey,Litsch has lost it he is garbage right now. keep litsch-send JP to the minors. lol Great game just like the first two in Tampa. What is the matter with Rios he is falling asleep out there he should have got that fly ball back in right away,God this team is playing poor. Well, Rios didmake up for that snooze Gary-Before tonight's game, Matt Stairs was hitting a measly .186 with RISP and probably a new Blue Jays record of .077 with RISP and 2 out. One might say he's lost it. I think its time to take a chance on purcey. Everyone has figured out listch and he doesnt have over powering stuff to make up for it. Another thing. I think Stairs has finally come down and become who he really is. Time to let him go or bench him. we cant keep his terrible hitting in this line up. Please Cito….this is torcher. I guess JP would make that call. By [email protected] on July 21, 2008 9:26 pm - Reply Go Baltimore opps I mean Jays.lol The problem with Stairs is he now has no trade value and stupid JP gave him a two year contract. I don't have the tube on that's how much this team sickens me and I love to watch baseball. Just checked gameday game over does anyone still think we have a chance,Start selling JP before it's to late. Lets start selling J.P, is the first step. 5 bucks? Maybe enough for some Taco Bell, so we could learn to scout in South and Central America. By welikeroywelikeroy on July 21, 2008 10:34 pm - Reply Tonight was the nail in the coffin for me. They played a pitcher who's been rocked lately and made him look like a quality pitcher. I have completely lost hope and will no longer use phrases such as "if they sweep this team, they will only be this much behind." I wont go out of my way to watch this team unless Roy Halladay or Shawn Marcum are pitching, or untill they bring up some of their promising prospects (Snider, Purcey, the catcher who's name escapes me.) I do think they still have a solid core for next year and that they should only rebuild if they feel they don't have enough money to sign a big bat (Ramirez, Teixera, Guerrero, Abreu, Giambi, Thome etc.) if they feel they can't add a big bat or 2 in the offseason then by all means start rebuilding this year. By [email protected] on July 21, 2008 10:54 pm - Reply Enigma. I feel the same way you do it's painfull to watch them Rios fell asleep in the field again and I can't understand it what is he thinkin of. The catcher might be diaz or arencibia you are looking for. Who is in favor of promoting the Lansing team to the majors and demoting the jays to lansing (save halladay and a few ofcourse)? I am gonna start watching in september where i will prolly see my first look at SNIDER and ARENCIBIA, they might decide on calling up Cecil too (i think they shoudl). GO COOPER GO! and now Ahrens is back on track to 1st round pick performance thats another solid player we have. Travis Snider ladies and gentlmen. Jordan, you mentioned it in your previous post, why do you think Adam Lind hasn't been moved up in the lineup yet ? The way he's playing he deserves to be in an "rbi spot." Also, it's not important but if you could help me out with this one i'd appreciate it because it confused my friends and I. when Jim Gordon took a bullet in the Dark Knight how did he survive it ? I recall a vest but was it him that put it on ? Not to much imformation on the dark knight please I havn't seen it yet. I don't see why JP is not bringing up minor league players at this time so we have something to watch because the jays are not worth watching enigma-thank you for that utube video on Snider. On Lind, I think Cito is working him in slowly to build his confidence and has done a great job at it. I think in one of his posts Jordan talked about it and suggested Cito was thinking of moving him to the 2nd hole with Rios leading off, which would be interesting to see. I wonder if the ballpark Snider was hitting in was the same size as a Major League one. Was it one of the 350 ones or was he hitting in a 400ft one. If he was hitting in the 400ft one then Snider could have very well won the HR Derby. By goodluckdoc on July 22, 2008 9:25 am - Reply Harry-I think the last think we ever want is any of our guys going into the HR derby again. Rios isn't the only one's swing that got screwed up by this competition. I still think Snider is going to be a good one, although I am not all that impressed with his Ba or risp stats this year. His HR's are up at 19, but everything else is down. I do not understand why we play him at DH most days instead of OF. If they want him to replace Stairs-great, but I think playing him day after day at DH, when the other OF's on the team are at best b- prospects-makes no sense. The kids only 20, we should not be pigeon holing him at that age-its stupidity. with you on Snider but what if he's another ortiz I think that would be great. Well last night was a very discouraging outing for the Blue Jays,It looks like Lystch has lost it so now what do they do with him nickname him Towers and let him keep pitchen or give him a stint in the minors and bring percey up,But the way JP thinks not a chance we might start to win. Garry, If McGowan is out longer than the next 3 weeks, which I think he is going to be, it might be time to call up both Purcey and Cecil, and send Litsch and Parrish back down. It appears they are getting to Litsch-probably because they started taking him more seriously after his start to the season and watched film on him to determne pitch patterns. I also don't think Parrish will last much longer for the same reason. I do believe Snider will be a good one, although I think we're tinkering with him and that, sometimes doesn't work. I just hope they don't mess him up-the DH thing for a 20 year old prospect totally amazes me. Is his BA still over 300 then? I hope so if not then that is not good at all. By the way Cooper is playing when do you expect him up for a full time job?, howe about snider for a full time job? Cecil? Arencibia? Diaz?Campell? Purcey? I am thinking Snider, Purcey, Arencibia, Diaz will be up next year (maybe campbell)….the others the year after. By goodluckdoc on July 22, 2008 11:49 am - Reply It looks like were not going to be contenders for at least 3 years JP should be gone and maybe Gillick will come back to Toronto then we will have a chance, At least he won't make the mistakes that JP does,hey but I'm only dreaming. Not much in trade rumors about Burnett,I think it's his contract another mess by JP. Sorry I read about Burnetts contract being a problem in trade rumors. You guys make an intersting point. Like most teams, the Jays introduce one prospect at a time into what is really an underachieving "bad" team. However, what if we introduced several prospects all at once – kind of like the Jays in the early 80s and the Flordia Marlins today? So the team sucks for a while. At least we have the enjoyment of watching the future develop before our eyes, while hopefully picking up some early first-round draft picks to restock the farm system. Moreover, our younger players would actually be seasoned veterans while still in their early 20s. The problem with the current team is that there is no room for optimism, no room for hope. Play the kids, and now you have your hope back long term. I'm all for bringing up the prospects but for some reason JP still thinks we can win is he daft. No, Snider's at .267ba/.343OBP/.477slg.; whereas last year he was .313BA/.377OBP/.525slg. and higher yet in his rookie year-so the trend is going in the wrong direction. I would expect Diaz, Arenciba, Campbell, Snider-as a minimum to be called up in September. I would hope we call up Purcey and Cecil sooner than that-if McGowan is out for the next 4 weeks. Cooper should be moved up to Dunedin, now. Whether we call him up in Spetember or not, should depend on how he does in Dunedin. I expect if he keeps progressing like he is, he'll spend next year between Dunedin, New Hampshire and possibly Syracuse. It's all going too depend on how he does at various levels. If he keeps hitting .340 to .400 at each level, we could see him up here sooner than later. However, Cooper does have some competition which I hadn't noticed before who is Brian Dopirak in Dunedin. I think we either signed him as a minor league free agent or traded for him-not sure, BUT he's hitting .298BA/.374OBP/.559slg and leading the league with 23 hr's and 76 rbi's in 90 games. Check him out at http://web.minorleaguebaseball.com/milb/stats/stats.jsp?n=Brian%20Dopirak&pos=90&sid=t424&t=p_pbp&pid=460590 I'm surprised they haven't moved Dopirak up to AA-but maybe Cooper will force that move. Brian Dopirak was named the Cubs Minor League Player of the Year in 2004 after batting .307 with 39 home runs and 120 RBI in 137 games for the Lansing Lugnuts of the Class A Midwest League…named league MVP and prospect of the year as his homer total led the league and was third among all Minor Leaguers…hit safely in 11 of his first 12 games, going 16-for-48 (.333) with three home runs and eight RBIs in that span…batted .390 with 11 doubles, 10 roundtrippers and 27 RBIs in 25 games in June…had five two-homer games and 36 multi-RBI affairs…had a season- and career-high six RBIs May 10 against the Peoria Chiefs, going 4-for-4 with a pair of home runs…had a 27-game hitting streak June 7-July 8, batting .393 with 28 RBIs in that span…also had a 10-game hitting streak Aug. 24-Sept. 3, going 20-for-42 (.476) with 16 RBIs. This kid fell of the map after 2004 until this year, so it's really hard to say whether he had a single moment of fame in 2004 or whether, with his insurgence again this year, if he's really got it or not. The best thing we could do to find out is bump him up to AA and see how he does. I read the write up on the Blue Jays home page I think this kid is for real. I just heard that Bedard is back on the block. What do you think if we traded the Mariners (some but not all these guys) Litche/Stairs/Eckstein/Barajas/Zaun for him. After all they are struggling and these guys may help them. If Bedard were to become our #2 started then dump Burnett for some good prospects, and then with the positions that need filling, go with Burts idea and have all the minor leaguers come up and play for the rest of the year. fredom. Where did you hear about Burnett. JP must be playing hardball where Burnett is concernd the Yankees are now looking at Washburn. Garryguy, Burnett or do you mean Bedard? freedom, I agree with Burt about having all the prospects come up BUT not until September-and Im sure Burt meant then, not now. If we bring them up early we have to move someone. If we do that we could miss a draft choice. At the moment, we might get 7-8 first and first sandwich picks next year. As miseable as the last two years have, I'm prepared to suffer through another 5 weeks to ensure we maintain those potential drat picks. It's the politicians. Blame them for the humidity… makes me feel better. http://redstatebluestate.mlblogs.com/ By redstatebluestate on July 22, 2008 3:43 pm - Reply Looks like Posada might be gone for the season. If he is, I'd bet The Yanks would have interest in Rod Barajas. Maybe we offer them a package of Burnett and Barajas for ??????? You guys fill in the blanks. gsumner, I definetely know where you are comming from by saying not bringing up the minors right now. But look how long it took the Rays who were until this year like a farm team in the majors. But like you said, we would have to move someone, and that is where the trade with the Mariners come in. I don't know if I like the idea of Lind in the 2 spot. I did look back to Jordan's previous work and read what Sumner mentioned. I think he's better served as a 5 or 6th guy the way this team is currently constructed but it does make sense to build his confidence up first. I think the Jays should find out what kind of interest anyone has on B.J. Ryan. He's a big contract that can be moved and they have Accardo and potentially Casey Janssen next year. Maybe Downs can even be a closer. 10 million dollars off the books can go a long way in signing a bat they so desperately need. As for the Dark knight I figured it out but I wont mention it out of respect to Garry and anyone else who hasn't seen it. Speaking of a movie has anyone seen the Rookie ? i've wanted to rent it but would like an opinion or 2 first. 1) Dopirak = MVP, ALL STAR, PROSPECT OF YEAR in 2004, after that nothing…he has been in the minors since 2002, which is a long time and he is 25 already. He was a 54th overall so he does have talent but i am not sure he is the one we need at first base…prolly another overbay perhaps or worse. Cooper seems like the real deal. 2)Snider – .267 is really really really concerning me…he is going down which is bad. If i saw a .267 BA for any hitter in the minors and i didn't know them I would consider them to be a non-impact player. I hope Snider turns it around…atleast the 19 HR are a bit comforting. I just hope he doesn't become the next Adam Dunn, either strike out or hit the long ball. 3)Bedard will cost much more than all the ppl you listed mainly because they are horrible and even Mariners don't need them. Mariners want prospects which we are not going to give up. I say we give up on Bedard. 4)FA Ben Sheets/ CC Sabathia sounds like a good option to me. I mean Milaukee will definately not sign them both so one of them is going to be an option and I think Milaukee won't sign either. Ben Sheets would look good in the Jays uniform. 5)Prospects shouldn't be brought up until September, I woudn't want to loose those draft picks too and they aren't mature enough yet i guess. IN september they face other minor leaguers so itsa bit more comfortable for them. 6) I don't know who the Yanks could possibly have that wed be interested in…the only person I can think of right now is Cano, Chamberlain and Jeter…either of which Yanks are never going to give up. Cano is young. Jeter is their face of franchise right now. Chamberlain is their future. I like the fact that JP is playing hardball…Washburn and Burnett arent in the same league for pitching…Burnett is far superior and they should pay for quality arms or go after more arms that would do nothing for you. If you want good pitchers, you give up good players. 7) Listsch = one more chance, Parrish = one more chance and we shoudl still keep Litsch, he is a great 5th Starter and is still young. Enigma thanks and rent the Rookie you wont be sorry. Freedom sorry miss read your post I thought you said Burnett was on the trading block now I see you ment Bedard.I like Bedard if only he can stay healthy. It's too bad that the Jays don't have any players in the minors that are ready to take a role as Major League players,If they did they wouldn't have to pick up all the misfits that all the other teams cut lose. I know we would all like to see some of the minor league players come up but none of them are ready to come up and stay,Rushing them will only cause futher problems and the Jays can't afford that. Bosoxbrian. Do you think the Jays will trade Burnett now that we are out of it. Leave a Reply to [email protected] Cancel reply
Q: Get variables always in differnet .phtml templates I have to use some variables again and again in different files. $_product = $this->getProduct(); $_helper = $this->helper('catalog/output'); $_productType = $_product->getTypeID(); $_productName = $_helper->productAttribute($_product, $_product->getName(), 'name'); $_manufacturer = $_product->getAttributeText('manufacturer'); $_decor = $_product->getAttributeText('decor'); $_serie = $_product->getAttributeText('serie'); $originalImageWidth = $this->helper('catalog/image')->init($_product, 'image')->getOriginalWidth(); $originalImageHeight = $this->helper('catalog/image')->init($_product, 'image')->getOriginalHeight(); $originalImageRelation = $originalImageWidth / $originalImageHeight; All this, I need in /templates/catalog/product/view.phtml and /templates/catalog/product/type/grouped.phtml and templates/catalog/product/media.phtml. Is there a way to gather this in a central file and reuse it in all this places? A: Yes, using magento you should be able to create a view helper which can be called from within the view. You can check This tutorial which should give you everything you need to solve your problem
If you want to programmatically detect if the Windows Phone has the front facing camera , you can easily do it using the Microsoft.Devices.Camera.IsCameraTypeSupported method . The Microsoft.Devices.Camera.IsCameraTypeSupported determines and lets the user know if the specified type of camera is supported on the windows phone device. Just pass the CameraType.FrontFacing to the IsCameraTypeSupported method which returns the Boolean value for identifying if the camera is supported .
Banca Pueyo es un banco español fundado en 1890 y situado en la localidad extremeña de Villanueva de la Serena, provincia de Badajoz. El banco se llama Pueyo como el fundador de la familia y hasta los años ochenta era prácticamente un banco local. Tenía la oficina central en Villanueva de la Serena, localidad de 25.000 habitantes, y sucursales en dos localidades pacenses. En 2004 se expandió hacia Andalucía y abrió su oficina número 75. En 2015, el banco celebró su 125 aniversario, durante el que abrió su oficina número 116. Ese año, atendía a cerca de 120.000 clientes. A 31 de diciembre de 2018, Banca Pueyo contaba con 115 oficinas y 296 empleados. El banco se identifica con el código de entidad número 0078. Referencias Enlaces externos Página web de Banca Pueyo Bancos de España Empresas fundadas en 1890 Villanueva de la Serena
A good piña colada should instantly transport you to warm sandy beaches and turquoise waters. What we don't want is a drink that tastes weak and watery, nor artificially tropical, as if someone dumped a bottle of tanning oil into the blender. This version produces a slushy frozen cocktail full of ripe pineapple and rich coconut flavor. Plus a good, strong hit of rum. Freezing the ingredients first means you can use less ice, leading to a more flavorful, less diluted drink. Ripe fresh pineapple or canned pineapple chunks are more flavorful than pineapple juice, plus their fiber helps thicken the drink. Coconut cream has a more natural flavor than Coco Lopez. Measuring solids by weight gives you better control over the ingredient ratios. In an airtight plastic container, combine pineapple, coconut cream, simple syrup, and 3/4 ounce lime juice, and transfer to freezer until frozen, at least one hour (the sugar in the mixture may prevent it from freezing solid; this is okay). In a blender, combine frozen pineapple mixture with ice-cold rum and ice and blend until thick and slushy. Taste, then blend in the remaining 1/4 ounce lime juice, if desired. Pour into a large glass, garnish with pineapple and/or a cherry, and serve, with or without an paper umbrella and straw. If you want to make multiple drinks, you can pre-batch up to a double recipe (a blender may not hold much more than that easily) in a single container, then divide after blending; for more than two drinks, use separate containers to hold more servings. If you can find truly ripe and sweet fresh pineapple, that will give you the best flavor. If not, your next best bet is to use the drained diced pineapple from a can. To make simple syrup, combine equal volumes of granulated sugar and water, then stir until sugar is completely dissolved; extra simple syrup can be refrigerated in an airtight container for up to 1 month.
Tested With vBulletin 3.8.x and 4.0.8, may work with older and newer versions. This mod introduces the [YOU] "BB Code." When a user types in [YOU] the forum will replace it with the Username of the User currently viewing the forum. For example if you make a post that says "[YOU] was here." and your username is BirdOPrey5 you will see, after submitting the post, "BirdOPrey5 was here." Meanwhile at the same time another user, say Joe 113, will see "Joe 113 was here." Why do this? The most prevalent reason is just to mess with people, use your imagination on how... But there can be some legitimate uses too. I have a "Welcome" thread on my forum that Welcome's every user by name. They will see a sticky in my off-topic with their username to make them feel special- eventually they'll figure out it was the [you] code, but not for a while usually. I have marked this mod both as BETA and Reusable Code. THIS IS A STABLE BETA and I run it on my forum without incident. It is a BETA because there are some minor missing features I'll detail a little later. However it works for my needs so it's not a priority for me to further develop. The code is reusable in hopes someone with more time and skill might finish everything and/or expand upon it. It's "Advanced" - There are settings in vBulletin options to enable, disable, block, and make users immune to this code. You can set a phrase to be displayed to guests/unregistered users who otherwise would simply see "Unregistered" in place of [you]. This [YOU] code works in search result thread titles, including "New Posts." Some other [you] codes don't work here. This isn't a true BB Code, it's a mod that acts LIKE a BB Code. Click on "Choose File" and browse to the product XML file that is included in this .zip. Click on "Import" and let the file import. You MUST go to the Mod Options to Enable this Mod and set its settings. It is OFF by default. Choose "Yes" to enable the mod. Block Usergroups - Any usergroups you enter here will not be allowed to use the [YOU] code in their posts, signatures, or user titles. If they attempt to use [YOU] everyone will simply see [YOU] - no replacement will be made. Disable [YOU] in Selected Forums - If you don't want to enable [YOU] in certain forums enter their forum ids here. If anyone uses [YOU] in these forums the other users will see [YOU] - no replacement will be made. [YOU] for Guests - This is the name, or word, you want unregistered/not logged in/guest users to see if they come across a post that uses [YOU]. In other [you] BB Codes guests would simply see "Unregistered" - now you can make it anything. I suggest simply "you." Immune Usergroups - Anyone in the immune usergroups will always see the code [YOU] no matter who uses it or where. This is useful possibly for mods or admins who don't want to risk being fooled by this code. The main limitation of this Beta is that the option "Block Usergroups From Using [YOU]" isn't fully implemented. It WILL block [YOU] from working in their posts and signatures, which is most important- but in certain areas like "New Post Preview" and "Review" the block doesn't work. This isn't a big deal because the other users of the forum will never have the [YOU] code work on posts by blocked users, but for the user who is blocked it may be confusing. If they view a preview of their post they will see the [YOU] code working but when they submit it, it won't work. I couldn't get this working in this version because it would require another database query (or at least changing an existing one) and that is beyond my ability at the moment. I hope to fix this one day, unless someone else comes along and does it first. Also when previewing your signature in your User CP you will see the [YOU] code in the signature, however it WILL work correctly in posts with the signature attached. As always use this mod at your own risk. I strongly suggest backing up your site before making any changes. Updated to v 0.92 - Added plugins to let [you] work in poll questions and options. *Installed. Excellent!* I just installed this on my board at http://allconsolegamers.com/ and seems to be working well! To get [YOU] to work in VB Advanced CMPS "Recent Threads" requires a manual file edit since hooks aren't available... also it will convert all [YOU] codes, it won't be able to be restricted by usergroup- but I find this is a lot better than nothing. In your /modules/ directory edit your recentthreads.php file. I suggest saving a backup of the original file just in case, but it's working fine for me. I just have to say that this tag is amazingly fun! I installed it right before April Fools this year for a specific purpose that day. We had a couple of threads get started that day that are still going, and going, and going.... all these users that no one had ever heard of and they are all posting and wondering why they see their name in a thread title! So much fun! (I did have to modify the code to make it only work in a couple of threads after some users realized how to use it in a negative way though. ) Thanks.
<?php defined('BASEPATH') OR exit('No direct script access allowed'); ?> <!DOCTYPE html> <html lang="en"> <head> <meta charset="UTF-8"> <title>JOBS</title> <?php includeJQuery(); ?> <?php includeBootstrap(); ?> <style type="text/css"> .dotted-bottom { border-bottom: 2px dotted gray; padding-top: 15px; padding-bottom: 15px; } .sectionTitle { padding-bottom: 15px; } </style> <script type="text/javascript"> var pageController = "Control_proveedor_ctrl"; </script> <script type="text/javascript" src="<?php echo base_url(); ?>includes/js/utilitiesJS.js"></script> <script type="text/javascript" src="<?php echo base_url(); ?>includes/js/JSControllers/Alta_cliente_JS.js"></script> <script type="text/javascript" src="<?php echo base_url(); ?>includes/js/JSControllers/Alta_cliente_DireccionFiscal_JS.js"></script> <script type="text/javascript" src="<?php echo base_url(); ?>includes/js/JSControllers/Alta_cliente_DireccionOperativa_JS.js"></script> <script type="text/javascript" src="<?php echo base_url(); ?>includes/js/JSControllers/Alta_cliente_Banco_JS.js"></script> <script type="text/javascript" src="<?php echo base_url(); ?>includes/js/JSControllers/Alta_cliente_agenda_JS.js"></script> <script type="text/javascript" src="<?php echo base_url(); ?>includes/js/JSControllers/Alta_cliente_Perfil_JS.js"></script> <script type="text/javascript" src="<?php echo base_url(); ?>includes/js/JSControllers/Alta_cliente_Servicio_JS.js"></script> <script type="text/javascript" src="<?php echo base_url(); ?>includes/js/JSControllers/Alta_cliente_Commons_JS.js"></script> </head> <body> <?=$menu ?> <div class="container"> <div class="row"> <div class="col-xs-12 col-sm-12 col-md-12 col-lg-12"> <div class="form-group"> <label for="cCliente">Proveedor en edición</label> <select id="cCliente" class="form-control"> <option value="-1">Ninguno</option> <?php foreach($proveedores as $proveedor){ ?> <option value="<?php echo $proveedor->id; ?>"><?php echo $proveedor->nombre; ?></option> <?php } ?> </select> </div> </div> </div> <div class="row" id="rowNuevoCliente"> <div class="col-xs-12 col-sm-12 col-md-12 col-lg-12"> <form action = "Alta_cliente_ctrl/nuevoCliente" method = "post" id = "form_alta" > <div class="form-group"> <label for="nombre">Nombre comercial</label> <input type="text" name="nombre" placeholder="Nombre comercial" class="form-control" required> </div> <div class="form-group"> <input type="submit" value="Crear" class="form-control btn btn-primary"> </div> </form> </div> </div> <!-- Inicia la sección de edición --> <span id="rowEdicionCliente"> <div class="row"> <div class="col-xs-12 col-sm-12 col-md-12 col-lg-12"> <form action = "Alta_cliente_ctrl/editarCliente" method = "post" id = "form-edita" > <div class="form-group"> <div class="row"> <div class="col-xs-12 col-sm-6 col-md-8 col-lg-8"> <label for="nombre">Nombre comercial</label> <input type="text" name="nombre" id="nombre" placeholder="Nombre comercial" class="form-control" required> </div> <div class="col-xs-12 col-sm-6 col-md-4 col-lg-4"> <label id="labelEstado">Estado: Activo</label> <button style="width: 100%;" id="btn-estado" class="btn btn-danger">Inactivar</button> </div> </div> </div> <input type="hidden" name="id" value="-1"> <input type="hidden" name="estadoActivo" value="1"> <div class="form-group"> <input type="submit" value="Actualizar" class="form-control btn btn-info"> </div> </form> </div> </div> <div class="row" style="background: rgb(238, 238, 238) none repeat scroll 0% 0%; border: 2px solid gray;"> <div class="col-xs-12 col-sm-12 col-md-12 col-lg-12"> <nav class="navbar navbar-default" style="background: none; box-shadow: none; border-color: transparent; margin: 0px;"> <div class="container-fluid"> <ul class="nav navbar-nav" id="main-menu-cliente"> <li> <a href="#" id="btn-direcciones-fiscales"> <span class="glyphicon glyphicon-home"></span> Direcciones fiscales </a> </li> <li> <a href="#" id="btn-direcciones-operativas"> <span class="glyphicon glyphicon-home"></span> Direcciones operativas </a> </li> <li> <a href="#" id="btn-bancos"> <span class="glyphicon glyphicon-usd"></span> Bancos </a> </li> <li> <a href="#" id="btn-agenda"> <span class="glyphicon glyphicon-phone-alt"></span> Agenda </a> </li> <li> <a href="#" id="btn-perfiles"> <span class="glyphicon glyphicon-user"></span> Perfiles </a> </li> <li> <a href="#" id="btn-servicios"> <span class="glyphicon glyphicon-th-list"></span> Servicios </a> </li> </ul> </div> </nav> </div> </div> <!-- Inicia sección de información financiera --> <?=$form_seccion1; ?> <?=$form_agenda; ?> </span> <!-- FIN ROW CLIENTE EDICIÓN --> </div> </body> </html>
3) knowledge transfer to support careers and regional development. These actions will help boosting career path of image analysts, by detecting early career vocations and increasing skills and know-how of analysts. to visit an institution, laboratory or industry in another participating COST Country or an approved non-COST country institution. Thus, bringing together researchers of different scientific backgrounds and image analysts within international multi-disciplinary projects will increase the potential for scientific breakthroughs, high-impact publications, creation of new research fields, building of interdisciplinary activities and creating collaborations that may not currently be represented by the local imaging community. STSMs will be offered on regular competitive calls throughout the duration of the COST Action CA15124 (NEUBIAS), from July 2016 until April 2020. The scientific context will be strictly limited to BioImage-Analysis-driven projects involving development of Image analysis technology and/or knowledge transfer in the field of Life Science. Access to and operation of Imaging instrumentation will in general not be considered as a component of the evaluated scientific projects. STSMs are coordinated by WG7 in NEUBIAS.
Join Nassau County for their 3rd Annual Barkfest event on Saturday, October 27th! East Meadow, NY - October 15th, 2013 - Nassau County Executive Edward Mangano, Pet Supplies Plus LI, and Long Island's K98.3 bring the third annual Nassau Barkfest, Long Island's largest pet costume contest and parade, on Sunday, October 27th from 12:00pm to 3:30pm at the Eisenhower Dog Run in East Meadow, rain or shine. For this Halloween-spirited celebration, guests are to bring their dogs and other pets dressed in costumes for a chance to win prizes. Costume judging and awarding of prizes will begin at 2:00pm. The event will be open to the public with free admission. Pet owners will enjoy music by K98.3 while they browse pet-related exhibitors and animal rescue organizations. All pets must be on leashes or in carriers, and current with vaccinations. Parking for the event will be in Eisenhower Park Field 7 near the golf course. Costume Judging & Prizes at 2:00p.m. Subject: LongIsland.com - Your Name sent you Article details of "Long Island Pet Owners Celebrate Halloween With Nassau County's Third Annual Barkfest"
Self-catering accommodation for 12 people in Seillans (83440) close to Shops. 200 m² accommodation for 12 people. This accommodation is located in the town of Seillans (Provence-Alpes-Cote d'Azur in France). Pets are forbidden. This accommodation is close to: Shops, Town centre, Sand beach, Lake, Supermarket, Restaurants. This accommodation is composed of: Kitchenette, Bathroom, Dining room. Self-catering accommodation for 9 people in Seillans (83440) close to Shops. 180 m² accommodation for 9 people. This accommodation is located in the town of Seillans (Provence-Alpes-Cote d'Azur in France) and is close to: Shops, Town centre, Sand beach, Lake, Supermarket, Restaurants. This accommodation is composed of: Kitchenette, Bathroom, Separate toilet, Living room. Self-catering accommodation for 8 people in Seillans (83440) close to Shops. 250 m² accommodation for 8 people. This accommodation is located in the town of Seillans (Provence-Alpes-Cote d'Azur in France) and is close to: Shops, Town centre, Supermarket, Restaurants. This accommodation is composed of: Kitchenette, Bathroom, Living room, Dining room, Mezzanine. Self-catering accommodation for 6 people in Seillans (83440) close to Shops. 196 m² accommodation for 6 people. This accommodation is located in the town of Seillans (Provence-Alpes-Cote d'Azur in France). Pets are forbidden. This accommodation is close to: Shops, Town centre, Lake, Supermarket, Restaurants. This accommodation is composed of: Kitchenette, Bathroom, Dining room. 0 m² accommodation for 8 people. This accommodation is located in the town of Seillans (Provence-Alpes-Cote d'Azur in France). Pets are forbidden. This accommodation is close to: Shops, Town centre, Sand beach, Lake, Supermarket, Restaurants. This accommodation is composed of: Kitchenette, Bathroom, Dining room, Playroom. 112 m² accommodation for 8 people. This accommodation is located in the town of Seillans (Provence-Alpes-Cote d'Azur in France). Pets are forbidden. This accommodation is close to: Shops, Town centre, Sand beach, Lake, Supermarket, Restaurants. This accommodation is composed of: Kitchenette, Bathroom, Separate toilet, Living room, Dining room. 100 m² accommodation for 6 people. This accommodation is located in the town of Seillans (Provence-Alpes-Cote d'Azur in France) and is close to: Shops, Town centre, Sand beach, Lake, Supermarket, Restaurants. This accommodation is composed of: Kitchenette, Bathroom, Separate toilet, Living room, Dining room. 160 m² accommodation for 8 people. This accommodation is located in the town of Seillans (Provence-Alpes-Cote d'Azur in France) and is close to: Shops, Town centre, Sand beach, Lake, Supermarket, Restaurants. This accommodation is composed of: Kitchenette, Bathroom, Dining room. Self-catering accommodation for 6 people in Fayence (83440) close to Shops. 0 m² accommodation for 6 people. This accommodation is located in the town of Fayence (Provence-Alpes-Cote d'Azur in France). Pets are forbidden. This accommodation is close to: Shops, Town centre, Sand beach, Lake. This accommodation is composed of: Kitchenette, Dining room. Self-catering accommodation for 12 people in Fayence (83440) close to Shops. 0 m² accommodation for 12 people. This accommodation is located in the town of Fayence (Provence-Alpes-Cote d'Azur in France). Pets are forbidden. This accommodation is close to: Shops, Town centre, Sand beach, Lake, Forest, Supermarket, Restaurants, Public pool. This accommodation is composed of: Kitchenette, Bathroom, Living room, Dining room.
Posted February 22, 2019 by AFP Toronto & filed under Inspiration, Opinion. Those who are interested in fundraising and want to know all about the important aspects of it can get really valuable information from fundraising blogs. The confusing part is that there are so many blogs which are concerned with this topic that it is hard to pick the best ones. For this purpose, I have done some research and surfaced 7 best fundraising blogs for 2019 that offer inspiration, good ideas, and informative content. If you want a high-quality education in fundraising these are the blogs you should look into. The AFP Toronto Blog (the one you're currently reading) – As the largest AFP Chapter in the world, the AFP Toronto blog hosts content that benefits both members and non-members to provide varied resources for today's fundraisers and those working in the non-profit sector. The Chapter also frequently accepts submissions from guest contributors to provide an array of diverse perspectives from people working directly in the field! Interested in contributing? Contact [email protected] to find out more. The Better Fundraising Blog – A great resource that claims to have the proven formula for effective fundraising. The Agitator – This blog offers ideas, applications, tools, processes, and case studies of break-through solutions in fundraising. Analytical Ones –Provides fundraising strategies rooted in insights driven from analytics and research. Bloomerang Blog – This blog helps nonprofit organizations to reach, engage, and retain the advocates they depend on to achieve their vision. Communicate! By Dennis Fischman –Aims to teach you how to win loyal friends for your nonprofit organization. Heroic Fundraising – A go-to blog for fresh industry insights. Clairification – This blog will motivate you and spark your passion for fundraising. Now in its third edition, the Speaker Discovery Series (SDS) is becoming AFP Toronto's premiere event showcasing the most promising upcoming speakers in the fundraising profession. Speakers come prepared to tell their personal stories in 8-minute speeches with no slide deck or props, and what transpires are powerful, emotional and dynamic presentations connected to the fundraising profession.
2800 S Andrews Rd – Spacious 2 bedroom, 1 bathroom home located in Yorktown, IN! This great home features a large carport and is located in a 55 and over community! Move right into this affordable home. SELLER FINANCING AVAILABLE!
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If you've ever seen a school of clown loaches, it's hard to resist bringing a couple of them home. It's even harder to imagine that this beautiful fish is eaten as food fish in Indonesia and Borneo, where it grows to over a foot in length. Fortunately for the clown loach, among aquarium enthusiasts, it's a staple in the community tank rather than on the dining table. Its orange and black striped body, red fins, and active behavior has made it one of the most popular loaches. The clown loach is a favorite for freshwater hobbyists. It is a peaceful fish and coexists well with nearly any tankmate. It is also an amusing species to watch and feed as it's active during the day. They also eat those annoying snails that can wind up in your aquarium. The Clown Loach is sometimes called a scaleless fish, but it actually does have small scales embedded in its skin. The Clown Loach hails from the rivers and tributaries of Malaysia, Borneo, Sumatra, and Kalimantan. During spawning periods, they migrate to flooded areas of the rainforest where soft water the color of tea flows through boggy, slow-moving streams. This loach prefers waterways that are slow-moving shaded by leafy plants and lined with plant detritus such as fallen leaves, twigs, and plants. Like all loaches, the Clown Loach has a long, pointed nose surrounded by sensitive whisker-like barbels and a sharp defensive spine beneath each eye. These spines are used for defense; in captivity, they may prick fingers snag on nets, so it's important to be careful when handling your pet. The Clown Loach's arched body is long and lean, ideal for cutting through the water. True to its name, its body is bright orangey-yellow, and its fins and tail are bright red. It has wide black V-shaped stripes along the sides of its body and a third black stripe running vertically through its eye. Peaceful with its own and other species, it prefers to have companions with which it will form a school. Virtually all non-aggressive fish are suitable as tankmates for clown loaches. Because they prefer to live in schools, it's wise to keep three or more in a group. They don't like bright light and will hide among plants or rocks as well as sleep in holes, caves and other hiding places. Clown Loaches are large schooling fish, and they are quite active. That means you will need a large tank with plenty of space for your pets to move around. At the same time, however, each Loach should have several hiding spots available; Loaches love enclosed spaces and will sometimes "hide" in caves, tubes, and other hidey-holes. Unlike many loaches who are only active at night, the Clown Loach can be active during the daytime hours—though it's likely to be liveliest in the early morning and after dark. To watch your loach at play during waking hours, consider installing a blue "moonlight" tube or another form of bluish lighting, which will encourage your pet to come out to play. Water quality is critical for keeping clown loaches healthy. Take care to keep the water very clean, well aerated and warm; an efficient filtration system and frequent water changes are critical. Tank lighting should be subdued, and the substrate should be soft and sandy. Clown Loaches appreciate plenty of hiding places which can be made of wood or rock; strong, sturdy plants are also a good addition. Clowns will accept a wide variety of dry and live foods, but their preference is for live foods, especially worms. You can even earthworms to them, as long as you harvest the worms from soil that hasn't been fertilized recently. Ideally, you should feed them several small meals throughout the day. Loaches are particularly prone to Ich infections; watch them closely whenever new fish or plants are added to the tank. In the unfortunate event that an infection does occur, keep in mind that loaches, like catfish, are very sensitive to some medications. Often dosages must be cut in half to be safe. Read product information carefully before treating your loach. Males can be identified by the tail, which is larger and hooks inward rather than pointing straight out from the body. Females are smaller and more slender. There are very few documented cases of clown loaches breeding in captivity. As a result, very little information is known about their breeding needs. Clown Loaches rarely or never breed in captivity. If a female does spawn in an aquarium setting, there is an excellent chance that they will not be fertilized and that she or her male counterparts will eat the eggs before they hatch. Virtually all Clown Loaches sold for aquaria are captured in the wild. It's important, when buying Clown Loaches, to select only those with bright colors and to wait until the fish are at least a couple of inches long (they are quite fragile in their earliest days). At the store, look carefully at the tank to be sure it is well kept and that the fish seem comfortable and healthy. If you see any dead fish, steer clear: there is a good chance you'll be buying a loach that's already infected with Ich. If you're not quite sure which fish are right for your aquarium, check out all of our other freshwater pet fish breed profiles.
Third Space Canary Wharf's restaurant, The Pearson Room is stylish yet cosy, vibrant and bustling, warm and inviting. With spectacular views over Canada Square Park, comfy, soft seating and plenty of function space, The Pearson Room is the perfect place to entertain clients or unwind with friends. The full menu is available in the bar and lounge as well as the restaurant, giving you a whole range of dining and drinks options. The Pearson Room is also available for private hire on Saturdays and Sundays. 15 points: bottle of champagne, 30 points: bottle of champagne & dinner for 2 to the value of £100, 50 points: bottle of champagne, dinner for 2 to the value of £100 & a voucher for Re:SPA treatment or receive a voucher back for 5% OFF your event total spend.
We use some of the latest dental technology. If you have a few minutes, enjoy this message from Dr. Doug. The E4D Nevo Scanner is an optical impression system using digital technology. It is used to create all porcelain crowns, onlays, inlays and veneers by digital methods and computer design. An intraoral scanner is used after tooth preparation and this information is manipulated by computer software to first design the porcelain restoration and then mill it from a solid porcelain block. This procedure can usually be done in one day and even in one appointment. DENTRIX® products include practice management software for dental offices, imaging software, patient education software, blood pressure monitoring software, computer-based training software, voice recognition software, and other products designed to enhance the dental office experience. This state-of-the-art software allows us to monitor your treatment, provide reminders about appointments and handle insurance and billing easily! An intraoral camera will reveal problems such as worn-out, defective amalgam restorations, fractured teeth, decay, open margins on existing crowns, plaque, etc. It is an excellent tool for the doctors to educate the patient and to help photograph problems to aid in billing the patient's insurance company. Our cameras allow us to show our patients what is happening with their teeth and gums. A picture is often worth a thousand words. The Waterlase® has been cleared for hard and soft tissue procedures for both children and adults. Waterlase® is distributed domestically and internationally for both hard and soft tissue dental applications. The Waterlase® system is a revolutionary new dental device that uses laser-energized water to cut teeth. BIOLASE received FDA clearance to market the Waterlase® system for use on hard tissue (teeth) on October 9, 1998. This combination of laser energy and water-spray creates "HYDROKINETIC™" energy, and is a patented technology invented by BIOLASE scientists and engineers. What are benefits of the Waterlase® ? The Waterlase® significantly improves patients' comfort in the dentist's chair: 98.5% of patients treated with the Waterlase™ system reported no discomfort during the procedure in a randomized, double-blind clinical trial conducted at the University of the Pacific. Because it does not cause heat or vibration in the mouth, Waterlase® may ease the pain and anxiety of patients who fear the vibration and high-pitched whine of traditional drills. In contrast, the Waterlase® makes a gentle "tapping" noise. Waterlase® uses a cool-water spray to cut teeth without generating heat. Conventional drills and lasers can overheat teeth during procedures, inducing discomfort and irreversibly damaging the soft tissue or pulp underneath. The Waterlase® system uses laser-energized water to cut teeth. The Waterlase® emits a laser beam that energizes a highly precise spray of air and water. Water droplets absorb the laser energy and become laser-energized water particles that, when directed at the tooth, rapidly remove enamel, dentin and decay/caries. We know our patients are concerned about x-ray exposure in our dental office. Your x-rays are taken only as necessary and as recommended by the American Dental Association. However, we have obtained the latest technology for the health and safety of our patients. Our new Digital X-rays reduce the radiation exposure by 90% compared to conventional film X-rays. they are faster and more comfortable than previously possible. Also, since the digital image appears instantly. No developing is required so no chemicals are used that could potentially get released into the environment. Digital X-rays are a dental technology breakthrough which allows us to utilize an electronic sensor instead of film. These sensors have comfortable rounded edges that produce an image on the computer screen that is as accurate as a conventional dental film and are more diagnostic. The digital picture can be magnified 300 times its normal size to enhance diagnosis, manipulated to correct contrast, and color adjusted to reveal hidden problems. Titanium implants are produced in accordance with the highest quality and hygiene standards. A gentle surgical procedure is used to place the implants in the jawbone. The implants remain undisturbed for a period of usually 6 weeks (in healthy patients with good bone quality and quantity), while the bone remodels around them, forming a strong biological bond, similar to the bone between your natural tooth roots and jawbone. Your new replacement teeth, which will be custom made with both functional and cosmetic needs in mind, will be firmly attached to the connector. Fabricating your new teeth involves one or more appointments to ensure proper size, shape, color, and fit. Helps to preserve the bone in the jaw- Removes the need to grind down healthy teeth for a bridge. Can eliminate the pain of ill-fitting partials and dentures. Makes replacement teeth stable for eating and smile with confidence. This is the closest possible replacement to natural teeth. Utilizing advanced dental treatment facilities and equipment. Experts in general dentistry for adults and children. Cosmetic dentistry specialists with expertise in porcelain veneers, bonding, bonding fillings and teeth whitening. Simple extractions, biopsies, and other oral surgery procedures are performed at the office. Our expertise helps you to better manage your overall dental care. We provide dental implants and tooth replacements for adults. We provide insurance billing and access to payment options. First of all, I love my dentist! I couldn't be happier with Dr. Alyson and Marie, who is a great conversationalist as well as totally professional. I thank Dr. Kushner for recommending Dr. Alyson. I miss her as well. So, yes, I'm a happy camper at Emery & Emery DDS and wish I still had insurance so I could visit you every 3 months like I used to when I was teaching. Another reason I enjoy having work done with you is because I enjoy watching those cooking programs. Today, they talked about grits and a shrimp combo. Since I love both foods, I shall try it at home. It is so relaxing going to your office and is a stress-reducer, not the opposite. 🙂 Thank you! Dr Alyson Emery always greets me with a smile and assuages my fears about dental procedures. She explains things carefully and sensitively. The entire team at Emery and Emery is excellent. They are the best! This office and staff are wonderful. Dr Doug was so kind and patient with my Mom. Dr. Emery was referred to me by a friend and also by yelp. I was impressed with the first visit. I am glad I found a great dentist close by. I highly recommend! Sue at the front desk is also very responsive in addressing my inquiries pertaining to my dental insurance & out of pocket expenses. I drive 25 miles to see Dr. Alyson, Kaylin, Sue and the entire team and have been a patient for nearly 11 years. I no longer dread coming to the dentist. Thank you for taking such good care of one of your more difficult patients. I love the use of technology with the exam. Digital x-rays and the computer system in the room is terrific. I have been visiting your practice since you began, even when I lived 400 miles away in San Francisco. The service has always been outstanding and I can't imagine going anywhere else. Thanks to the entire staff for their professionalism and friendly personalities. I had a terrible fear of dentists in general, and as a result, was left with a mouth full of terrible teeth. I am leaving with a smile beyond my wildest dreams and undying gratitude to Dr. Alyson and Dr. Doug for helping me to change my life, starting with my smile.
The selction of high quality and ultra reliable loudspeaker and crossover components enable high sound pressure levels with sound quality. The RS Energy system is available as Energy 165. The 2-way system hay a 26mm tweeter. Our goal and our passion is perfect music reproduction in the automobile.
Biodegradation of nonylphenol during aerobic composting of sewage sludge under two intermittent aeration treatments in a full-scale plant. Authors: Zheng, Guodi and Wang, Tieyu and Niu, Mingjie and Chen, Xijuan and Liu, Changli and Wang, Yuewei and Chen, Tongbin The urbanization and industrialization of cities around the coastal region of the Bohai Sea have produced large amounts of sewage sludge from sewage treatment plants. Research on the biodegradation of nonylphenol (NP) and the influencing factors of such biodegradation during sewage sludge composting is important to control pollution caused by land application of sewage sludge. The present study investigated the effect of aeration on NP biodegradation and the microbe community during aerobic composting under two intermittent aeration treatments in a full-scale plant of sewage sludge, sawdust, and returned compost at a ratio of 6:3:1. The results showed that 65% of NP was biodegraded and that Bacillus was the dominant bacterial species in the mesophilic phase. The amount of NP biodegraded in the mesophilic phase was 68.3%, which accounted for 64.6% of the total amount of biodegraded NP. The amount of NP biodegraded under high-volume aeration was 19.6% higher than that under low-volume aeration. Bacillus was dominant for 60.9% of the composting period under high-volume aeration, compared to 22.7% dominance under low-volume aeration. In the thermophilic phase, high-volume aeration promoted the biodegradation of NP and Bacillus remained the dominant bacterial species. In the cooling and stable phases, the contents of NP underwent insignificant change while different dominant bacteria were observed in the two treatments. NP was mostly biodegraded by Bacillus, and the rate of biodegradation was significantly correlated with the abundance of Bacillus (r?=?0.63, p?<?0.05). Under aeration, Bacillus remained the dominant bacteria, especially in the thermal phase; this phenomenon possibly increased the biodegradation efficiency of NP. High-volume aeration accelerated the activity and prolonged the survival of Bacillus. The risk of organic pollution could be decreased prior to sewage sludge reuse in soil by adjusting the ventilation strategies of aerobic compost measurements. Copyright © 2018 Elsevier Ltd. All rights reserved.</p> Journal: Environmental pollution DOI: 10.1016/j.envpol.2018.03.112
we could not make inference. know the MP generalized inverse of X is . of the elements of that matrix. Definition: Suppose Y is an n ×1 vector of random variables. is distinct from a covarince matrix. Theorem: Covariance matrices are always positive semi-definite.