Datasets:

---

siddharthtumre

/

jnlpba-split

like 0

[ "Activity", "was", "mediated", "through", "the", "core", "elements", "." ]

[ 0, 0, 0, 0, 0, 1, 2, 0 ]

[ "Maximal", "accumulation", "of", "either", "c-fos", "and", "c-jun", "messenger", "RNA", "(", "mRNA", ")", "occurred", "30", "minutes", "after", "LPS", "addition", "." ]

[ 0, 0, 0, 0, 3, 4, 4, 4, 4, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Before", "treatment", ",", "at", "regular", "intervals", "during", "the", "treatment", ",", "1", "week", "and", "finally", "6", "weeks", "after", "termination", "of", "treatment", ",", "the", "effects", "on", "glucocorticoid", "receptor", "(", "GR", ")", "and", "methallothionein", "(", "MTIIa", ")", "mRNA", "expression", "levels", "were", "examined", "in", "peripheral", "lymphocytes", "using", "a", "solution", "hybridization", "assay", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0, 0, 0, 0, 0, 0 ]

[ "Although", "IL-2", "secretion", "was", "increased", "in", "the", "presence", "of", "anti-CD28", "MoAb", ",", "neonatal", "T", "cell", "IL-2", "production", "remained", "lower", "than", "in", "adults", "." ]

[ 0, 9, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 7, 8, 8, 9, 0, 0, 0, 0, 0, 0, 0 ]

[ "These", "results", "indicate", "a", "variation", "in", "transcriptional", "regulation", "rather", "than", "mRNA", "stability", "between", "the", "alleles", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0 ]

[ "Further", "analysis", "reveals", "that", "the", "inducible", "phosphorylation", "of", "I", "kappa", "B", "alpha", "maps", "to", "two", "serines", "in", "the", "N", "terminus", "of", "the", "protein", "(", "residues", "32", "and", "36", ")", "and", "that", "the", "mutation", "of", "either", "residue", "is", "sufficient", "to", "abolish", "ligand-induced", "degradation", ",", "whereas", "both", "residues", "must", "be", "mutated", "to", "abolish", "inducible", "phosphorylation", "of", "the", "protein", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 10, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Experiments", "with", "a", "blocking", "antibody", "to", "IL-4R", "alpha", "showed", "that", "this", "chain", "remains", "an", "essential", "component", "of", "the", "IL-13", "receptor", "complex", "on", "MDMac", "." ]

[ 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 0, 5, 0 ]

[ "Further", ",", "complete", "activation", "of", "T", "cells", "requires", "at", "least", "two", "signals", ",", "one", "that", "stimulates", "an", "increase", "in", "intracellular", "calcium", "and", "one", "that", "stimulates", "enzymatic", "processes", "including", "kinases", "." ]

[ 0, 0, 0, 0, 0, 7, 8, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "The", "first", "was", "to", "abruptly", "terminate", "tumor", "necrosis", "factor-induced", "NF-kappaB", "binding", "to", "the", "enhancer", "sequences", "in", "U1", "monocytic", "cells", ",", "using", "a", "short", "pulse", "of", "exogenous", "tumor", "necrosis", "factor", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 10, 0 ]

[ "Signal", "transduction", "abnormalities", "in", "T", "lymphocytes", "from", "patients", "with", "advanced", "renal", "carcinoma", ":", "clinical", "relevance", "and", "effects", "of", "cytokine", "therapy", "." ]

[ 0, 0, 0, 0, 7, 8, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0 ]

[ "Oligonucleotide", "primers", "based", "on", "the", "murine", "sequence", "were", "used", "to", "construct", "a", "quantitative", "reverse", "transcription-PCR", "assay", "for", "gene", "expression", "." ]

[ 0, 0, 0, 0, 0, 1, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "TNF-alpha", "release", "peaked", "at", "24", "h", "and", "decreased", "thereafter", ",", "and", "it", "was", "dose", "dependent", "and", "preceded", "by", "an", "increase", "of", "TNF-alpha", "mRNA", "detectable", "after", "3", "h", "of", "stimulation", "with", "mAb", "L243", "." ]

[ 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0 ]

[ "Our", "results", "provide", "the", "first", "evidence", "that", "both", "GATA-1", "and", "C/EBPbeta", "synergistically", "transactivate", "the", "promoter", "of", "an", "eosinophil-specific", "granule", "protein", "gene", "and", "that", "FOG", "may", "act", "as", "a", "negative", "cofactor", "for", "the", "eosinophil", "lineage", ",", "unlike", "its", "positively", "regulatory", "function", "for", "the", "erythroid", "and", "megakaryocyte", "lineages", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 9, 0, 0, 0, 1, 0, 0, 1, 2, 2, 2, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 8, 8, 0 ]

[ "Histamine", "transiently", "increased", "cAMP", "and", "c-fos", "expression", "through", "H2", "receptors", "." ]

[ 0, 0, 0, 0, 0, 1, 0, 0, 9, 10, 0 ]

[ "However", ",", "the", "phenotypic", "analysis", "of", "NF-AT", "-deficient", "mice", "supports", "the", "idea", "that", "there", "are", "tissue-", "and", "gene-", "specific", "functions", "as", "well", "." ]

[ 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Phosphatidylserine", "(", "PS", ")", ",", "another", "anionic", "glycerophospholipid", ",", "binds", "to", "mCD14", "with", "lower", "apparent", "affinity", "than", "does", "PtdIns", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Binding", "to", "RBD", "increased", "from", "undetectable", "levels", "in", "resting", "platelets", "to", ">", "50", "%", "of", "total", "Rap1", "within", "30", "s", "after", "stimulation", "." ]

[ 0, 0, 9, 0, 0, 0, 0, 0, 7, 8, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0 ]

[ "It", "can", "only", "be", "activated", "in", "a", "tissue-specific", "manner", "by", "elements", "that", "lie", "downstream", "of", "the", "initiation", "site", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 0 ]

[ "Overexpression", "of", "a", "V14Rho", "construct", "incapable", "of", "membrane", "localization", "(", "CAAX", "deleted", ")", "abolishes", "PMA-induced", "AP-1", "transcriptional", "activation", "." ]

[ 0, 0, 0, 1, 2, 0, 0, 0, 0, 0, 1, 2, 0, 0, 0, 9, 0, 0, 0 ]

[ "The", "conventional", "means", "of", "studying", "Epstein-Barr", "virus", "(", "EBV", ")", "-induced", "cytotoxic", "T-lymphocyte", "(", "CTL", ")", "memory", ",", "by", "in", "vitro", "stimulation", "with", "the", "latently", "infected", "autologous", "lymphoblastoid", "cell", "line", "(", "LCL", ")", ",", "has", "important", "limitations", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 5, 6, 6, 0, 5, 0, 0, 0, 0, 0, 0 ]

[ "The", "failure", "to", "express", "a", "class", "II", "gene", "in", "at", "least", "one", "such", "mutant", "line", "has", "been", "mapped", "to", "the", "MHC", "class", "II", "X", "box", ",", "a", "conserved", "transcriptional", "element", "in", "the", "promoter", "region", "." ]

[ 0, 0, 0, 0, 0, 1, 2, 2, 0, 0, 0, 0, 0, 5, 6, 0, 0, 0, 0, 0, 1, 2, 2, 2, 2, 0, 0, 1, 2, 2, 0, 0, 1, 2, 0 ]

[ "The", "antagonistic", "effects", "of", "gamma-IFN", "are", "not", "merely", "restricted", "to", "enzymatic", "activities", "." ]

[ 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "In", "situ", "hybridization", "and", "Northern", "blot", "analysis", "suggest", "that", "Spi-B", "gene", "expression", "increases", "during", "B", "cell", "maturation", "and", "decreases", "during", "T", "cell", "maturation", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "We", "have", "identified", "two", "human", "pre-B-cell", "lines", "that", "contain", "extremely", "low", "levels", "of", "OTF-2", "yet", "still", "express", "high", "levels", "of", "steady-state", "immunoglobulin", "heavy-chain", "mRNA", "in", "vivo", "and", "efficiently", "transcribe", "an", "immunoglobulin", "gene", "in", "vitro", "." ]

[ 0, 0, 0, 0, 5, 6, 6, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 3, 4, 4, 4, 0, 0, 0, 0, 0, 0, 1, 2, 0, 0, 0 ]

[ "As", "a", "first", "step", "in", "understanding", "the", "mechanism", "of", "decreased", "binding", "affinity", "in", "New", "World", "primates", ",", "we", "used", "reverse", "transcription-PCR", "to", "clone", "the", "glucocorticoid", "receptor", "from", "squirrel", "monkey", "liver", "and", "have", "compared", "the", "sequence", "to", "receptor", "sequences", "obtained", "from", "owl", "monkey", "liver", ",", "cotton-top", "tamarin", "B95-8", "cells", ",", "and", "human", "lymphocytes", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 5, 6, 6, 6, 0, 0, 7, 8, 0 ]

[ "This", "enhancement", "was", "eliminated", "if", "a", "conserved", "20-bp", "sequence", "was", "removed", "from", "the", "intron", "or", "if", "a", "dominant-negative", "ets-binding", "factor", "was", "co-transfected", "with", "the", "reporter", "gene", "." ]

[ 0, 0, 0, 0, 0, 0, 1, 2, 2, 0, 0, 0, 0, 1, 0, 0, 0, 9, 10, 10, 0, 0, 0, 0, 1, 2, 0 ]

[ "However", ",", "the", "first", "two", "footprints", "resided", "in", "sequences", "that", "were", "largely", "dispensable", "for", "transient", "activity", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "METHODS", ":", "PBMCs", "and", "sera", "from", "8", "patients", "with", "extrinsic", "asthma", "(", "mean", "IgE", ",", "285+/-100", "IU/mL", ")", ",", "3", "patients", "with", "HIE", "(", "mean", "IgE", ",", "7050+/-1122", "IU/mL", ")", ",", "and", "14", "nonatopic", "control", "subjects", "(", "mean", "IgE", ",", "112+/-28", "IU/mL", ")", "were", "analyzed", "." ]

[ 0, 0, 7, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0 ]

[ "A", "diverged", "homeobox", "gene", ",", "HB24", ",", "which", "is", "known", "to", "be", "induced", "following", "lymphocyte", "activation", ",", "was", "introduced", "into", "Jurkat", "T", "cells", "under", "the", "control", "of", "a", "constitutive", "promoter", "." ]

[ 0, 1, 2, 2, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 5, 6, 6, 0, 0, 0, 0, 0, 1, 2, 0 ]

[ "Involvement", "of", "NF-chi", "B", "and", "NF-IL6", "in", "induction", "of", "IL-6", "transcription", "by", "monocytes", "was", "demonstrated", "using", "deleted", "forms", "of", "the", "IL-6", "promoter", "." ]

[ 0, 0, 9, 10, 0, 9, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 0 ]

[ "The", "frequency", "of", "Oct2-positive", "clones", "was", "1/15", ",", "000", "in", "both", "libraries", "." ]

[ 0, 0, 0, 5, 6, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "The", "ability", "of", "Qp", "to", "bind", "signal", "transducer", "and", "activator", "of", "transcription", "(", "STAT", ")", "proteins", "was", "directly", "demonstrated", "by", "electrophoretic", "mobility-shift", "assay", ",", "and", "mutation", "of", "potential", "STAT-binding", "sites", "reduced", "Qp", "responsiveness", "to", "Janus", "kinase", "(", "JAK", ")", "-1", "." ]

[ 0, 0, 0, 1, 0, 0, 9, 10, 10, 10, 10, 10, 10, 10, 10, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 0, 1, 0, 0, 9, 10, 10, 10, 10, 10, 0 ]

[ "The", "nature", "of", "the", "nuclear", "factor", "(", "s", ")", "that", "control", "TNF-alpha", "gene", "transcription", "in", "humans", "remains", "obscure", ",", "although", "NF-kappaB", "has", "been", "suggested", "." ]

[ 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0 ]

[ "This", "enhancer", "is", "inducible", "in", "K562", "human", "erythroleukemia", "cells", ",", "increasing", "linked", "gamma-globin", "promoter", "/luciferase", "gene", "expression", "to", "170-fold", "over", "an", "enhancerless", "construct", "." ]

[ 0, 1, 0, 0, 0, 5, 6, 6, 6, 0, 0, 0, 1, 2, 9, 0, 0, 0, 0, 0, 0, 1, 2, 0 ]

[ "The", "average", "expansion", "was", "2.7", "repeats", "." ]

[ 0, 0, 0, 0, 0, 0, 0 ]

[ "Unexpectedly", ",", "a", "second", ",", "stronger", "RBP-Jkappa-binding", "site", ",", "which", "lies", "within", "the", "intracellular", "domain", "close", "to", "the", "transmembrane", "region", "and", "significantly", "augments", "association", "with", "RBP-Jkappa", ",", "was", "not", "needed", "for", "oncogenesis", "or", "for", "transcriptional", "activation", "." ]

[ 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "However", ",", "analysis", "of", "the", "viral", "control", "elements", "and", "the", "cellular", "factors", "that", "regulate", "adenoviral", "gene", "expression", "in", "lymphocytes", "has", "not", "been", "reported", "." ]

[ 0, 0, 0, 0, 0, 1, 2, 2, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 7, 0, 0, 0, 0, 0 ]

[ "We", "also", "show", "that", "the", "IL-7", "-induced", "enhancement", "of", "the", "AP-1", "-DNA", "binding", "activity", "is", "not", "cyclosporin", "A-sensitive", "." ]

[ 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Rat", "spleen", "and", "peripheral", "blood", "lymphocytes", "express", "progesterone", "receptors", "whose", "concentration", "is", "increased", "greatly", "during", "the", "early", "phase", "of", "pregnancy", "." ]

[ 0, 0, 0, 7, 8, 8, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "The", "protein", "components", "of", "this", "complex", "are", "specifically", "competed", "by", "an", "AP1", "consensus", "motif", "and", "were", "shown", "by", "supershift", "to", "include", "c-Jun", "and", "c-Fos", ",", "suggesting", "that", "this", "binding", "site", "is", "an", "AP1", "motif", "and", "that", "the", "Jun", "and", "Fos", "families", "of", "transcription", "factors", "play", "a", "role", "in", "the", "regulation", "of", "the", "kappa", "light", "chain", "gene", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 0, 0, 0, 0, 0, 0, 0, 9, 0, 9, 0, 0, 0, 0, 1, 2, 0, 0, 1, 2, 0, 0, 0, 9, 10, 10, 10, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 2, 0 ]

[ "We", "describe", "here", "a", "novel", "gene", "preferentially", "expressed", "in", "bursal", "B", "cells", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 8, 0 ]

[ "This", "activation", "is", "mediated", "by", "the", "host", "transcription", "factor", "NF-kappa", "B", "[", "G.Nabel", "and", "D.Baltimore", ",", "Nature", "(", "London", ")", "326", ":", "711-717", ",", "1987", "]", "." ]

[ 0, 0, 0, 0, 0, 0, 9, 10, 10, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Present", "data", "suggest", "that", "H2O2", "and", "vanadate", "are", "likely", "to", "inhibit", "the", "activity", "of", "intracellular", "tyrosine", "phosphatase", "(", "s", ")", ",", "leading", "to", "enhanced", "STAT3", "tyrosine", "phosphorylation", "and", "hence", "its", "translocation", "to", "the", "nucleus", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "They", "also", "demonstrate", "for", "the", "first", "time", "the", "occurrence", "of", "T", "cell", "responses", "against", "EBV", "transactivating", "factors", ",", "which", "might", "be", "central", "in", "the", "control", "of", "virus", "reactivation", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "This", "viral", "reactivation", "was", "associated", "with", "increased", "NF-kappaB", "nuclear", "translocation", "in", "patients", "'", "PBMCs", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 7, 0 ]

[ "After", "ELISA", "screening", ",", "mAb", "18C7", "was", "selected", "for", "its", "specificity", "towards", "the", "HBD", "." ]

[ 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 9, 0 ]

[ "We", "conclude", "that", "the", "serum", "response", "of", "the", "human", "TSP", "1", "gene", "requires", "the", "coordinated", "function", "of", "an", "SRE-", "and", "NF-Y-binding", "site", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 0, 0, 0, 0, 0, 0, 1, 2, 2, 2, 0 ]

[ "The", "transcription", "factor", "NF-kappaB", "has", "been", "shown", "to", "play", "a", "role", "in", "protecting", "cells", "against", "death", "mediated", "by", "TNF", "We", "show", "here", "that", "NF-kappaB", "also", "has", "a", "role", "in", "regulating", "Fas", "/", "APO-1", "/", "CD95", "-mediated", "death", ",", "a", "major", "pathway", "of", "peripheral", "T", "cell", "death", "." ]

[ 0, 9, 10, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 9, 0, 9, 0, 9, 0, 0, 0, 0, 0, 0, 0, 7, 8, 8, 0, 0 ]

[ "A", "significant", "correlation", "between", "high", "lymphocytic", "infiltration", "(", "2.5", "points", ")", ",", "low", "body", "mass", "and", "fat", "was", "identified", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "However", ",", "its", "interactions", "with", "these", "histone", "acetyltransferases", "are", "not", "equivalent", ",", "as", "CBP", "and", "p300", ",", "but", "not", "P/CAF", ",", "utilize", "EKLF", "as", "a", "substrate", "for", "in", "vitro", "acetylation", "within", "its", "trans-", "activation", "region", "." ]

[ 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 9, 0, 9, 0, 0, 0, 9, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0 ]

[ "Nonadherent", "neutrophils", "were", "removed", "by", "sealing", "and", "inverting", "the", "culture", "well", "." ]

[ 0, 7, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Altered", "transcription", "of", "c-fos", "and", "c-myc", "genes", "was", "the", "primary", "effect", "of", "heat", "shock", "." ]

[ 0, 0, 0, 1, 0, 1, 2, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Cytomegalovirus", "immediate", "early", "genes", "upregulate", "interleukin-6", "gene", "expression", "." ]

[ 1, 2, 2, 2, 0, 9, 0, 0, 0 ]

[ "These", "experiments", "show", "that", "FGF-1", "stimulation", "of", "Jurkat", "T", "cells", "provides", "a", "second", "signal", "that", "augments", "TCR-mediated", "IL-2", "production", "." ]

[ 0, 0, 0, 0, 9, 0, 0, 5, 6, 6, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0 ]

[ "Overexpression", "of", "the", "p50", ",", "p65", "and", "Rel", "proteins", "in", "these", "cells", "showed", "that", "significant", "activation", "of", "the", "IL-2R", "alpha", "kappa", "B", "site", "was", "observed", "only", "with", "Rel", "and", "Rel", "plus", "p65", "." ]

[ 0, 0, 0, 9, 0, 9, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 1, 2, 2, 0, 0, 0, 0, 9, 0, 9, 0, 9, 0 ]

[ "The", "transactivation", "of", "multiple", "cis", "elements", ",", "especially", "S", "and", "X2", ",", "of", "the", "DR", "alpha", "proximal", "promoter", "in", "group", "II", "CID", "cells", "is", "CIITA", "dependent", "." ]

[ 0, 0, 0, 1, 2, 2, 0, 0, 1, 0, 1, 0, 0, 0, 1, 2, 2, 2, 0, 5, 6, 6, 6, 0, 9, 0, 0 ]

[ "These", "results", "suggest", "that", "ML-9", "should", "be", "useful", "for", "studying", "the", "mechanisms", "of", "monocytic", "differentiation", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Dephosphorylation", "of", "4E-BP1", "was", "also", "observed", "when", "U-937", "cells", "were", "induced", "to", "differentiate", "into", "monocytes/macrophages", "following", "treatment", "with", "retinoic", "acid", "or", "DMSO", "." ]

[ 0, 0, 9, 0, 0, 0, 0, 5, 6, 0, 0, 0, 0, 0, 7, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "These", "findings", "establish", "that", "STAT1", "and", "STAT5", ",", "and", "possibly", "STAT3", ",", "are", "activated", "upon", "stimulation", "of", "precursor", "B", "cells", "with", "IL-7", "." ]

[ 0, 0, 0, 0, 9, 0, 9, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 7, 8, 8, 0, 9, 0 ]

[ "The", "absence", "in", "I", "kappa", "B", "gamma-1", "and", "I", "kappa", "B", "gamma-2", "of", "a", "protein", "kinase", "A", "site", "whose", "phosphorylation", "modulates", "p70", "I", "kappa", "B", "gamma", "inhibitory", "activity", "suggests", "that", "alternative", "RNA", "splicing", "may", "be", "used", "to", "generate", "I", "kappa", "B", "gamma", "isoforms", "that", "respond", "differently", "to", "intracellular", "signals", "." ]

[ 0, 0, 0, 9, 10, 10, 10, 0, 9, 10, 10, 10, 0, 0, 1, 2, 2, 2, 0, 0, 0, 9, 9, 10, 10, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 10, 10, 0, 0, 0, 0, 0, 0, 0 ]

[ "The", "finding", "that", "functionally", "distinct", "isoforms", "of", "STAT5", "are", "activated", "during", "the", "early", "and", "late", "differentiation", "stages", "of", "granulocytes", "suggests", "that", "they", "might", "be", "involved", "in", "regulating", "different", "biological", "functions", "in", "these", "cells", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "IL-4", "secreted", "by", "activated", "T", "cells", "is", "a", "pleiotropic", "cytokine", "affecting", "growth", "and", "differentiation", "of", "diverse", "cell", "types", "such", "as", "T", "cells", ",", "B", "cells", ",", "and", "mast", "cells", "." ]

[ 9, 0, 0, 7, 8, 8, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0, 7, 8, 0, 0, 7, 8, 0 ]

[ "In", "contrast", ",", "levels", "of", "the", "transcriptional", "factor", "AP-1", ",", "which", "is", "not", "known", "to", "be", "important", "in", "B", "cell", "Ig", "production", ",", "were", "reduced", "by", "TGF-beta", "." ]

[ 0, 0, 0, 0, 0, 0, 9, 10, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 9, 0, 0, 0, 0, 0, 9, 0 ]

[ "Involvement", "of", "Janus", "kinase", "/signal", "transducer", "and", "activator", "of", "transcription", "and", "protein", "kinase", "C", "signaling", "pathways", "." ]

[ 0, 0, 9, 10, 9, 10, 10, 10, 10, 10, 0, 9, 10, 10, 0, 0, 0 ]

[ "Likewise", ",", "activation", "of", "this", "reporter", "construct", "by", "tumor", "necrosis", "factor-alpha", "depended", "on", "the", "SP-1", "site", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 0, 0, 0, 1, 2, 0 ]

[ "Translocation", "(", "3", ";", "14", ")", "(", "q27", ";", "q11", ")", ":", "a", "new", "variant", "translocation", "in", "a", "patient", "with", "non-Hodgkin", "'s", "lymphoma", "of", "B-cell", "type", "with", "BCL6", "rearrangement", "." ]

[ 1, 2, 2, 2, 2, 2, 2, 2, 2, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0 ]

[ "Dysregulation", "of", "cytokines", "secreted", "by", "T", "cells", "may", "play", "an", "important", "role", "in", "the", "pathogenesis", "of", "AIDS", "." ]

[ 0, 0, 9, 0, 0, 7, 8, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "IL-2", "and", "IL-7", "were", "equivalent", "in", "their", "ability", "to", "induce", "tyrosine", "phosphorylation", "of", "STAT5A", "and", "STAT5B", "and", "to", "facilitate", "binding", "of", "these", "STATs", "to", "an", "immobilized", "GAS", "element", "." ]

[ 9, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 9, 0, 0, 0, 0, 0, 0, 9, 0, 0, 1, 2, 2, 0 ]

[ "The", "expression", "and", "activity", "of", "NF-kappa", "B", "and", "Sp1", "were", ",", "therefore", ",", "analyzed", "in", "isolated", "T", "cells", "and", "DCs", "from", "humans", "and", "mice", "." ]

[ 0, 0, 0, 0, 0, 9, 10, 0, 9, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0, 7, 0, 0, 0, 0, 0 ]

[ "The", "median", "dissociation", "constant", "(", "Kd", ")", "was", "similar", "in", "all", "three", "groups", "of", "patients", "and", "in", "healthy", "women", "(", "mean", "+/-", "S.D.", "(", "range", ")", ":", "PHP", ",", "1.2", "+/-", "1.0", "(", "0.2-4", ")", "x", "10", "(", "-10", ")", "M", ";", "SH", ",", "0.6", "+/-", "0.4", "(", "0.2-1.2", ")", "x", "10", "(", "-10", ")", "M", ";", "RT", ",", "1.1", "+/-", "0.5", "(", "0.4-1.9", ")", "x", "10", "(", "-10", ")", "M", ";", "controls", ",", "1.0", "+/-", "0.6", "(", "0.3-2.6", ")", "x", "10", "(", "-10", ")", "M", ")", ".", "However", ",", "the", "maximal", "binding", "capacity", "(", "Nmax", ")", "was", "significantly", "enhanced", "in", "PHP", "(", "3.9", "+/-", "1.9", "(", "1.3-7.6", ")", "fmol/10", "(", "7", ")", "cells", "vs.", "2.3", "+/-", "0.9", "(", "1.1-4.4", ")", "fmol/10", "(", "7", ")", "cells", "in", "controls", ";", "P", "=", "0.0006", ")", "and", "decreased", "in", "SH", "(", "0.8", "+/-", "0.5", "(", "0.2-1.6", ")", "fmol/10", "(", "7", ")", "cells", "vs.", "2.3", "+/-", "0.9", "(", "1.1-4.4", ")", "fmol/10", "(", "7", ")", "cells", "in", "controls", ";", "P", "=", "0.0001", ")", ",", "whereas", "no", "changes", "were", "seen", "in", "RT", "(", "2.3", "+/-", "0.7", "(", "1.2-3.3", ")", "fmol/10", "(", "7", ")", "cells", "vs.", "2.3", "+/-", "0.9", "(", "1.1-4.4", ")", "fmol/10", "(", "7", ")", "cells", "in", "controls", ")", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Pax-5", "codes", "for", "the", "transcription", "factor", "BSAP", "which", "is", "expressed", "throughout", "B", "cell", "development", "except", "in", "terminally", "differentiated", "plasma", "cells", "." ]

[ 9, 0, 0, 0, 9, 10, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 8, 8, 0 ]

[ "Several", "small", "molecules", ",", "an", "antisense", "oligonucleotide", ",", "and", "gene", "therapeutic", "agents", "that", "inhibit", "NF-kappa", "b", "activation", "have", "been", "described", "." ]

[ 0, 0, 0, 0, 0, 1, 2, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0 ]

[ "From", "our", "results", ",", "we", "conclude", "that", "Rap1", "activation", "in", "platelets", "is", "an", "important", "common", "event", "in", "early", "agonist-induced", "signalling", ",", "and", "that", "this", "activation", "is", "mediated", "by", "an", "increased", "intracellular", "Ca2+", "concentration" ]

[ 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 7, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Ran", "GTP-dependent", "association", "of", "CRM1", "with", "these", "nucleoporins", "was", "reconstituted", "in", "vitro", "." ]

[ 9, 0, 0, 0, 9, 0, 0, 9, 0, 0, 0, 0, 0 ]

[ "BEAD-1", "blocked", "the", "ability", "of", "the", "TCR", "delta", "enhancer", "(", "Edelta", ")", "to", "activate", "a", "promoter", "when", "located", "between", "the", "two", "in", "a", "chromatin-integrated", "construct", "." ]

[ 1, 0, 0, 0, 0, 0, 1, 2, 2, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 0 ]

[ "Role", "for", "the", "Epstein-Barr", "virus", "nuclear", "antigen", "2", "in", "viral", "promoter", "switching", "during", "initial", "stages", "of", "infection", "." ]

[ 0, 0, 0, 9, 10, 10, 10, 10, 0, 1, 2, 0, 0, 0, 0, 0, 0, 0 ]

[ "The", "dominant", "interference", "activity", "of", "Ikaros", "isoforms", "unable", "to", "bind", "DNA", "and", "their", "effects", "in", "lymphocyte", "development", "suggest", "that", "Ikaros", "works", "in", "concert", "with", "other", "factors", "." ]

[ 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0 ]

[ "As", "a", "result", ",", "the", "cases", "of", "deficiency-cold", "syndrome", "(", "DCS", ")", "had", "a", "normal", "concentration", "of", "plasma", "cortisol", "but", "a", "lowered", "content", "of", "GCR", "in", "leukocytes", "when", "compared", "with", "the", "normal", "control", "(", "P", "less", "than", "0.05", ")", ";", "the", "cases", "of", "deficiency-heat", "syndrome", "(", "DHS", ")", "had", "a", "higher", "concentration", "of", "plasma", "cortisol", "than", "the", "normal", "control", "(", "P", "less", "than", "0.05", ")", "and", "a", "slightly", "higher", "content", "of", "GCR", "in", "leukocytes", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 7, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 7, 0 ]

[ "We", "hypothesized", "that", "an", "intracellular", "vitamin", "D", "binding", "protein", "(", "IDBP", ")", ",", "present", "in", "both", "nuclear", "and", "cytoplasmic", "fractions", "of", "NWP", "cells", ",", "or", "another", "protein", "(", "s", ")", "may", "cause", "or", "contribute", "to", "the", "steroid", "hormone-resistant", "state", "in", "NWP", "by", "disruption", "of", "the", "receptor", "dimerization", "process", "and/or", "by", "interference", "of", "receptor", "complex", "binding", "to", "the", "consensus", "response", "elements", "present", "in", "the", "enhancer", "regions", "of", "steroid-responsive", "genes", "." ]

[ 0, 0, 0, 0, 9, 10, 10, 10, 10, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 5, 6, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 5, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 1, 2, 2, 0, 0, 0, 1, 2, 0, 1, 2, 0 ]

[ "The", "modified", "vectors", "were", "used", "to", "transduce", "human", "hematopoietic", "cell", "lines", ",", "cord", "blood-derived", "CD34", "(", "+", ")", "stem/progenitor", "cells", ",", "and", "murine", "bone", "marrow", "repopulating", "stem", "cells", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 5, 6, 6, 6, 0, 7, 8, 8, 8, 8, 8, 8, 8, 0, 0, 5, 6, 6, 6, 6, 6, 0 ]

[ "One", "of", "these", "clones", ",", "pZVH14", ",", "activated", "the", "HIV", "promoter", "construct", "containing", "a", "mutation", "in", "the", "NF", "kappa", "B", "site", "." ]

[ 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 2, 2, 0, 0, 0, 0, 0, 1, 2, 2, 2, 0 ]

[ "Lactobacilli", "also", "increased", "tumor", "necrosis", "factor", "-alphaand", "interleukin", "-1betaproduction", "and", "activated", "NF-kappaB", "in", "THP-1", "cells", "and", "increased", "tumor", "necrosis", "factor", "-alphaproduction", "by", "human", "monocytes", "." ]

[ 0, 0, 0, 9, 10, 10, 0, 9, 0, 0, 0, 9, 0, 9, 10, 0, 0, 9, 10, 10, 0, 0, 7, 8, 0 ]

[ "Selective", "activation", "of", "STAT1alpha", "at", "the", "IFN-gamma", "receptor", "is", "achieved", "by", "specific", "interaction", "between", "a", "cytosolic", "tyrosine", "motif", "including", "Y440", "in", "the", "IFN-gamma", "receptor", "alpha-chain", "and", "the", "SH2", "domain", "of", "STAT1alpha", "." ]

[ 0, 0, 0, 9, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 0, 9, 0, 0, 9, 10, 10, 0, 0, 9, 10, 0, 9, 0 ]

[ "When", "tested", "for", "its", "ability", "to", "block", "calcineurin", "-dependent", "signaling", "in", "Jurkat", "cells", ",", "expression", "of", "this", "``", "B-subunit", "knock-out", "''", "(", "BKO", ")", "construct", "suppressed", "reporter", "gene", "activity", "driven", "by", "NF-AT", ",", "the", "pivotal", "promoter", "element", "for", "interleukin", "(", "IL", ")", "-2", "gene", "induction", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 2, 2, 2, 2, 2, 0, 1, 2, 0, 0, 0, 9, 0, 0, 0, 1, 2, 0, 1, 2, 2, 2, 2, 2, 0, 0 ]

[ "Tyloxapol", "(", "0.05", "to", "0.1", "%", "wt/vol", ")", "effectively", "scavenges", "the", "oxidant", "hypochlorous", "acid", "(", "HOCl", ";", "1", "to", "7.5", "mM", ")", "in", "vitro", ",", "and", "protects", "from", "HOCl-mediated", "lung", "injury", "in", "rats", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Other", "cellular", "parameters", ",", "such", "as", "glycosidase", "activities", ",", "cytokine", "release", ",", "and", "filament", "expression", ",", "returned", "to", "levels", "similar", "to", "that", "observed", "in", "uninduced", "cells", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0 ]

[ "Finally", ",", "it", "was", "observed", "that", "the", "rate", "of", "decay", "of", "vimentin", "mRNA", "upon", "actinomycin", "D", "administration", "was", "decreased", "in", "heat-", "and", "cadmium-pretreated", "cells", "in", "comparison", "to", "untreated", "cells", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 3, 4, 0, 0, 0, 0, 0, 0, 0, 5, 6, 6, 6, 0, 0, 0, 7, 8, 0 ]

[ "Transactivation", "of", "the", "interleukin-1alpha", "promoter", "by", "human", "T-cell", "leukemia", "virus", "type", "I", "and", "type", "II", "Tax", "proteins", "." ]

[ 0, 0, 0, 1, 2, 0, 9, 10, 10, 10, 10, 10, 10, 10, 10, 10, 10, 0 ]

[ "RESULTS", ":", "Cord", "lymphocytes", "revealed", "a", "greater", "proliferation", "rate", "with", "PHA", "and", "alphaCD3", "than", "adult", "lymphocytes", "(", "p", "=", "0.0081", "and", "0.0023", ",", "respectively", ")", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Indeed", ",", "the", "availability", "of", "selective", "and", "orally", "active", "proteasome", "inhibitors", "should", "prove", "useful", "in", "delineating", "the", "roles", "of", "the", "proteasome", "and", "NF-kappa", "B", "in", "other", "pathophysiological", "conditions", "such", "as", "cancer", "and", "heart", "disease", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "Nitric", "oxide", "selectively", "reduces", "endothelial", "expression", "of", "adhesion", "molecules", "and", "proinflammatory", "cytokines", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 9, 10, 0 ]

[ "This", "study", "examined", "the", "role", "of", "various", "cis-acting", "regulatory", "elements", "in", "the", "lipopolysaccharide", "(", "LPS", ")", "induction", "of", "the", "human", "TNF-alpha", "promoter", "in", "cells", "of", "monocytic", "lineage", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 0, 0, 0, 7, 8, 0 ]

[ "A", "full-length", "PML/RARalpha", "cDNA", "driven", "by", "the", "CD11b", "promoter", "was", "expressed", "in", "transgenic", "mice", "." ]

[ 0, 0, 1, 2, 0, 0, 0, 1, 2, 0, 0, 0, 0, 0, 0 ]

[ "Evidence", "for", "normal", "vitamin", "D", "receptor", "messenger", "ribonucleic", "acid", "and", "genotype", "in", "absorptive", "hypercalciuria", "." ]

[ 0, 0, 0, 3, 4, 4, 4, 4, 4, 0, 0, 0, 0, 0, 0 ]

[ "Immunoelectron", "microscopy", "revealed", "LANDs", "to", "be", "globular", ",", "electron-dense", "structures", "morphologically", "distinct", "from", "the", "annular", "structures", "characteristic", "of", "PML", "NBs", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "These", "results", "indicated", "that", ",", "in", "abdominal", "obesity", ",", "the", "GR", "binding", "capacity", "in", "MNL", "is", "influenced", "by", "the", "changes", "in", "glucose", "transport", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 7, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "These", "data", "suggest", "that", "abnormal", "myelopoiesis", "due", "to", "PML/RARalpha", "expression", "is", "an", "early", "event", "in", "oncogenic", "transformation", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]

[ "We", "show", "here", "that", "the", "minimum", "region", "of", "the", "ferritin", "H-gene", "promoter", "that", "is", "able", "to", "confer", "transcriptional", "regulation", "by", "heme", "in", "FLCs", "to", "a", "reporter", "gene", "is", "77", "nucleotides", "upstream", "of", "the", "TATA", "box", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 5, 0, 0, 1, 2, 0, 1, 2, 2, 0, 0, 1, 2, 0 ]

[ "Displacement", "of", "an", "E-box-binding", "repressor", "by", "basic", "helix-loop-helix", "proteins", ":", "implications", "for", "B-cell", "specificity", "of", "the", "immunoglobulin", "heavy-chain", "enhancer", "." ]

[ 0, 0, 0, 9, 10, 0, 9, 10, 10, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 0 ]

[ "These", "results", "appear", "to", "indicate", "that", "suppression", "of", "cytokine", "and", "NO", "generation", "by", "Azeptin", "results", "at", "least", "partially", "from", "the", "inhibition", "of", "NF-kappa", "B", "activation", "." ]

[ 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0 ]