diff --git a/suspect/mrsobjects.py b/suspect/mrsobjects.py
index 7fb4764..3785dc1 100644
--- a/suspect/mrsobjects.py
+++ b/suspect/mrsobjects.py
@@ -324,3 +324,46 @@ class MRSSpectrum(MRSBase):
         suspect.adjust_frequency : equivalent function
         """
         return self.fid().adjust_frequency(frequency_shift).spectrum()
+
+    def slice_hz(self, lower_bound, upper_bound):
+        """
+        Creates a slice object to access the region of the spectrum between
+        the specified bounds, in Hertz.
+        
+        Parameters
+        ----------
+        lower_bound : float
+            The lower frequency bound of the region, in Hertz.
+        upper_bound : float
+            The upper frequency bound of the region, in Hertz.
+        
+        Returns
+        -------
+        out : Slice
+        """
+        lower_index = numpy.floor((lower_bound + self.sw / 2) / self.df)
+        upper_index = numpy.ceil((upper_bound + self.sw / 2) / self.df)
+        if lower_index < 0:
+            raise ValueError("Could not create a slice for lower bound {}, value is outside range".format(lower_bound))
+        if upper_index < 0:
+            raise ValueError("Could not create a slice for upper bound {}, value is outside range".format(upper_bound))
+        return slice(int(lower_index), int(upper_index))
+
+    def slice_ppm(self, lower_bound, upper_bound):
+        """
+        Creates a slice object to access the region of the spectrum between
+        the specified bounds, in PPM.
+
+        Parameters
+        ----------
+        lower_bound : float
+            The lower frequency bound of the region, in PPM.
+        upper_bound : float
+            The upper frequency bound of the region, in PPM.
+
+        Returns
+        -------
+        out : Slice
+        """
+        return self.slice_hz(self.ppm_to_hertz(lower_bound),
+                             self.ppm_to_hertz(upper_bound))

Slice spectrum
It should be possible to generate a slice object for a specified frequency range from an MRSSpectrum object, which can be used to extract specific regions of a spectrum (or set of spectra).
diff --git a/tests/test_mrs/test_core.py b/tests/test_mrs/test_core.py
index 97a9f0e..2ea638e 100644
--- a/tests/test_mrs/test_core.py
+++ b/tests/test_mrs/test_core.py
@@ -1,6 +1,7 @@
 import suspect
 
 import numpy
+import pytest
 
 
 def test_adjust_zero_phase():
@@ -15,3 +16,23 @@ def test_adjust_first_phase():
     numpy.testing.assert_almost_equal(phased_data[0], -1j)
     numpy.testing.assert_almost_equal(phased_data[-1], numpy.exp(1j * 0.4 * numpy.pi))
     numpy.testing.assert_almost_equal(phased_data[5], 1)
+
+
+def test_slice_hz():
+    data = suspect.MRSData(numpy.ones(1024), 1e-3, 123)
+    spectrum = data.spectrum()
+    whole_slice = spectrum.slice_hz(-500, 500)
+    assert whole_slice == slice(0, 1024)
+    restricted_slice = spectrum.slice_hz(-100, 200)
+    assert restricted_slice == slice(409, 717)
+    with pytest.raises(ValueError):
+        too_large_slice = spectrum.slice_hz(-1000, 1000)
+
+
+def test_slice_ppm():
+    data = suspect.MRSData(numpy.ones(1000), 1e-3, 123)
+    spectrum = data.spectrum()
+    a_slice = spectrum.slice_ppm(5.7, 3.7)
+    assert a_slice == slice(377, 623)
+    reversed_slice = spectrum.slice_ppm(3.7, 5.7)
+    assert a_slice == slice(377, 623)

pip install -e .
parse_log_pytest
requirements.txt
pytest mock
apt-get update apt-get install -y gcc
3.9
requirements.txt
pytest --no-header -rA --tb=line --color=no -p no:cacheprovider -W ignore::DeprecationWarning
alabaster==0.7.16
asteval==1.0.6
asttokens==3.0.0
attrs==25.3.0
babel==2.17.0
beautifulsoup4==4.13.3
bleach==6.2.0
certifi==2025.1.31
charset-normalizer==3.4.1
comm==0.2.2
debugpy==1.8.13
decorator==5.2.1
defusedxml==0.7.1
dill==0.3.9
docutils==0.21.2
exceptiongroup==1.2.2
executing==2.2.0
fastjsonschema==2.21.1
idna==3.10
imagesize==1.4.1
importlib_metadata==8.6.1
iniconfig==2.1.0
ipykernel==6.29.5
ipython==8.18.1
jedi==0.19.2
Jinja2==3.1.6
jsonschema==4.23.0
jsonschema-specifications==2024.10.1
jupyter_client==8.6.3
jupyter_core==5.7.2
jupyterlab_pygments==0.3.0
lmfit==1.3.3
MarkupSafe==3.0.2
matplotlib-inline==0.1.7
mistune==3.1.3
mock==5.2.0
nbclient==0.10.2
nbconvert==7.16.6
nbformat==5.10.4
nbsphinx==0.9.7
nest-asyncio==1.6.0
numpy==2.0.2
packaging==24.2
pandocfilters==1.5.1
Parsley==1.3
parso==0.8.4
pexpect==4.9.0
platformdirs==4.3.7
pluggy==1.5.0
prompt_toolkit==3.0.50
psutil==7.0.0
ptyprocess==0.7.0
pure_eval==0.2.3
pydicom==2.4.4
Pygments==2.19.1
pytest==8.3.5
python-dateutil==2.9.0.post0
PyWavelets==1.6.0
pyzmq==26.3.0
referencing==0.36.2
requests==2.32.3
rpds-py==0.24.0
scipy==1.13.1
six==1.17.0
snowballstemmer==2.2.0
soupsieve==2.6
Sphinx==7.4.7
sphinxcontrib-applehelp==2.0.0
sphinxcontrib-devhelp==2.0.0
sphinxcontrib-htmlhelp==2.1.0
sphinxcontrib-jsmath==1.0.1
sphinxcontrib-qthelp==2.0.0
sphinxcontrib-serializinghtml==2.0.0
stack-data==0.6.3
-e git+https://github.com/openmrslab/suspect.git@f65efe543321e1d75d6ecbc7c22be73ab84d3d8a#egg=suspect
tinycss2==1.4.0
tomli==2.2.1
tornado==6.4.2
traitlets==5.14.3
typing_extensions==4.13.0
uncertainties==3.2.2
urllib3==2.3.0
wcwidth==0.2.13
webencodings==0.5.1
zipp==3.21.0

name: suspect
channels:
  - defaults
  - https://repo.anaconda.com/pkgs/main
  - https://repo.anaconda.com/pkgs/r
  - conda-forge
dependencies:
  - _libgcc_mutex=0.1=main
  - _openmp_mutex=5.1=1_gnu
  - ca-certificates=2025.2.25=h06a4308_0
  - ld_impl_linux-64=2.40=h12ee557_0
  - libffi=3.4.4=h6a678d5_1
  - libgcc-ng=11.2.0=h1234567_1
  - libgomp=11.2.0=h1234567_1
  - libstdcxx-ng=11.2.0=h1234567_1
  - ncurses=6.4=h6a678d5_0
  - openssl=3.0.16=h5eee18b_0
  - pip=25.0=py39h06a4308_0
  - python=3.9.21=he870216_1
  - readline=8.2=h5eee18b_0
  - setuptools=75.8.0=py39h06a4308_0
  - sqlite=3.45.3=h5eee18b_0
  - tk=8.6.14=h39e8969_0
  - tzdata=2025a=h04d1e81_0
  - wheel=0.45.1=py39h06a4308_0
  - xz=5.6.4=h5eee18b_1
  - zlib=1.2.13=h5eee18b_1
  - pip:
      - alabaster==0.7.16
      - asteval==1.0.6
      - asttokens==3.0.0
      - attrs==25.3.0
      - babel==2.17.0
      - beautifulsoup4==4.13.3
      - bleach==6.2.0
      - certifi==2025.1.31
      - charset-normalizer==3.4.1
      - comm==0.2.2
      - debugpy==1.8.13
      - decorator==5.2.1
      - defusedxml==0.7.1
      - dill==0.3.9
      - docutils==0.21.2
      - exceptiongroup==1.2.2
      - executing==2.2.0
      - fastjsonschema==2.21.1
      - idna==3.10
      - imagesize==1.4.1
      - importlib-metadata==8.6.1
      - iniconfig==2.1.0
      - ipykernel==6.29.5
      - ipython==8.18.1
      - jedi==0.19.2
      - jinja2==3.1.6
      - jsonschema==4.23.0
      - jsonschema-specifications==2024.10.1
      - jupyter-client==8.6.3
      - jupyter-core==5.7.2
      - jupyterlab-pygments==0.3.0
      - lmfit==1.3.3
      - markupsafe==3.0.2
      - matplotlib-inline==0.1.7
      - mistune==3.1.3
      - mock==5.2.0
      - nbclient==0.10.2
      - nbconvert==7.16.6
      - nbformat==5.10.4
      - nbsphinx==0.9.7
      - nest-asyncio==1.6.0
      - numpy==2.0.2
      - packaging==24.2
      - pandocfilters==1.5.1
      - parsley==1.3
      - parso==0.8.4
      - pexpect==4.9.0
      - platformdirs==4.3.7
      - pluggy==1.5.0
      - prompt-toolkit==3.0.50
      - psutil==7.0.0
      - ptyprocess==0.7.0
      - pure-eval==0.2.3
      - pydicom==2.4.4
      - pygments==2.19.1
      - pytest==8.3.5
      - python-dateutil==2.9.0.post0
      - pywavelets==1.6.0
      - pyzmq==26.3.0
      - referencing==0.36.2
      - requests==2.32.3
      - rpds-py==0.24.0
      - scipy==1.13.1
      - six==1.17.0
      - snowballstemmer==2.2.0
      - soupsieve==2.6
      - sphinx==7.4.7
      - sphinxcontrib-applehelp==2.0.0
      - sphinxcontrib-devhelp==2.0.0
      - sphinxcontrib-htmlhelp==2.1.0
      - sphinxcontrib-jsmath==1.0.1
      - sphinxcontrib-qthelp==2.0.0
      - sphinxcontrib-serializinghtml==2.0.0
      - stack-data==0.6.3
      - tinycss2==1.4.0
      - tomli==2.2.1
      - tornado==6.4.2
      - traitlets==5.14.3
      - typing-extensions==4.13.0
      - uncertainties==3.2.2
      - urllib3==2.3.0
      - wcwidth==0.2.13
      - webencodings==0.5.1
      - zipp==3.21.0
prefix: /opt/conda/envs/suspect

tests/test_mrs/test_core.py::test_slice_hz tests/test_mrs/test_core.py::test_slice_ppm
tests/test_mrs/test_core.py::test_adjust_zero_phase tests/test_mrs/test_core.py::test_adjust_first_phase
suspect/mrsobjects.py
suspect/mrsobjects.py