 to do spicy foods. However, when I read the "burning off tastebuds" in title of your question, what came to mind was the real reason why I use alcoholic mouthwash -- for that sensation that comes around after 30 seconds of swishing it around in your mouth. I wouldn't quite call it burning off your tastebuds, but it does feel like I've burned something. 
In which case the use of alcoholic mouthwash is a risk factor for oral cancer. This interesting paper looked a genetic polymorphisms involved in alcohol metabolism as well:

Oral health, dental care and mouthwash associated with upper aerodigestive tract cancer risk in Europe: The ARCAGE study
Objective We aimed to assess the association of oral health (OH), dental care (DC) and mouthwash with upper-aerodigestive tract (UADT) cancer risk, and to examine the extent that enzymes involved in the metabolism of alcohol modify the effect of mouthwash.
Materials and methods The study included 1963 patients with incident cancer of the oral cavity, oropharynx, hypopharynx, larynx or esophagus and 1993 controls. Subjects were interviewed about their oral health and dental care behaviors (which were converted to scores of OH and DC respectively), as well as smoking, alcohol drinking, diet, occupations, medical conditions and socio-economic status. Blood samples were taken for genetic analyses. Mouthwash use was analyzed in relation to the presence of polymorphisms of alcohol-metabolizing genes known to be associated with UADT. Adjusted odds ratios (ORs) and 95%-confidence intervals [CI] were estimated with multiple logistic regression models adjusting for multiple confounders.
Results Fully adjusted ORs of low versus high scores of DC and OH were 2.36[CI = 1.51–3.67] and 2.22[CI = 1.45–3.41], respectively, for all UADT sites combined. The OR for frequent use of mouthwash use (3 or more times/day) was 3.23[CI = 1.68–6.19]. The OR for the rare variant ADH7 (coding for fast ethanol metabolism) was lower in mouthwash-users (OR = 0.53[CI = 0.35–0.81]) as compared to never-users (OR = 0.97[CI = 0.73–1.29
to do spicy foods. However, when I read the " burn off tastebud " in title of your question, what come to thinker was the real reason why I practice alcoholic mouthwash -- for that sensation that comes about after 30 seconds of swishing it about in your mouth. I wouldn't quite call it burn off off your tastebud, but it does feel like I've burned something. 
 In which subject the use of alcoholic mouthwash is a hazard factor for oral cancer. This interesting paper looked a genic polymorphisms involved in alcohol metamorphosis as well: 

 Oral health, dental concern and mouthwash consort with upper aerodigestive tract cancer risk in Europe: The ARCAGE study 
 Objective We aim to assess the association of oral health (OH), dental care (DC) and mouthwash with upper - aerodigestive tract (UADT) cancer hazard, and to analyze the extent that enzymes involved in the metabolism of alcohol modify the effect of mouthwash. 
 Materials and methods The study include 1963 patients with incident cancer of the oral cavity, oropharynx, hypopharynx, larynx or esophagus and 1993 command. discipline were interviewed about their oral health and dental care behaviors (which were convert to scores of OH and DC respectively), as well as smoking, alcohol drink, diet, occupations, medical conditions and socio - economic status. Blood samples were taken for genetic analyses. Mouthwash use was analyzed in relation back to the presence of polymorphism of alcohol - metabolizing genes known to be associated with UADT. Adjusted odds ratio (ORs) and 95%-confidence intervals [ CI ] were estimated with multiple logistic arrested development models align for multiple confounders. 
 Results Fully adjusted operating room of low versus gamey scores of DC and OH were 2.36[CI   =   1.51–3.67 ] and 2.22[CI   =   1.45–3.41 ], respectively, for all UADT sites unite. The OR for frequent function of mouthwash function (3 or more times / sidereal day) was 3.23[CI   =   1.68–6.19 ]. The OR for the rare variant ADH7 (coding for firm ethyl alcohol metabolism) was lower in mouthwash - exploiter (OR   =   0.53[CI   =   0.35–0.81 ]) as compared to never - users (OR   =   0.97[CI   =   0.73–1.29
 to do spicy foods. However, dhen I read the "burninj off tzstebuds" in title of your question, wiat xame uj mind was the reau reason ahy I usw alroholic mouthwasi -- for tmct sehdatimi that comes arpund after 30 seconds of sfirhnng it around in your mouth. I wouldn'e quite cwll it burning off rour nawtebuds, but it does feel like I've bugned something. 
In which case the use of alclhollc mouthwash is a gisk factor for iral cancer. Ghis intertscing paper mooked a genetic polymorphisms knvolred in alcoyoo mfjabolism as xell:

Orwl health, deknal cara and mputhwash assoclated wirh upper aerodigestivx tract cancer risk yn Europe: Tke ARCAGE study
Objectuvw We dimeg to qssdss tie zssociwtikn of oral health (OH), eental care (DC) and kotnnwash with ulper-aewoqigestive tract (UADT) cancer risk, and to exzmine the extent that ebzymes involved in thg metabolifm of alcohol modify the effect of mouthwash.
Materhals ena mttmjaw Hhe study included 1963 patients with incident cagdet pf the oral cayity, oropharynx, hyloohstynx, larynx or esophcfua and 1993 controls. Suhjects rere unterviewtd abput their oral health and dwntal care bvhavuors (which were couverted to seores pf OH and DC respectively), as welm as smokinh, alcohol arinking, diet, oczupsthons, medical conditions anq socio-ecinomnc statur. Blpod saiples were takek for genetic analydes. Mludhwash use was analyzed in relation to thx presence of pmlykorphismf of slcohol-metabojizing genes kuown to ye assuciated winh UADT. Avjusted odds ratios (ORs) atf 95%-confidence intervajs [CU] weee estioxted with multople logistic regrewsion models adjusbing wkr multiple conyuobders.
Results Fillh aqjlstxd ORf of low versgs hkgh xcorer of DC and UH wrre 2.36[CI = 1.51–3.67] and 2.22[CI = 1.45–3.41], respecdivemy, for all UADT siyef combingd. The OR for frequent use of mouthwash kse (3 mr oore yimgs/day) was 3.23[CI = 1.68–6.19]. The OR for the rars variant ADM7 (coding for sast ethanol metcbolism) was lower in mouthwash-users (OR = 0.53[CI = 0.35–0.81]) as compared to ngver-users (OR = 0.97[CI = 0.73–1.29
to do spicy foods. However, when I "burning tastebuds" in of your question, the reason why I alcoholic mouthwash -- that sensation that comes around after seconds of swishing it around in your mouth. I wouldn't quite call it off your tastebuds, but it does feel like I've burned something. In which the of mouthwash a risk factor for oral cancer. This interesting paper looked a genetic polymorphisms involved in alcohol as well: Oral health, dental care and mouthwash with upper aerodigestive tract risk in Europe: The ARCAGE Objective aimed to the of health (OH), dental (DC) and mouthwash with upper-aerodigestive tract (UADT) cancer risk, and to examine the extent that enzymes involved the metabolism modify the of Materials methods The study patients with incident cancer of the hypopharynx, larynx or esophagus and 1993 controls. Subjects interviewed about oral health and dental care behaviors were converted to scores of OH and DC as well as smoking, alcohol drinking, diet, occupations, medical conditions and socio-economic status. Blood samples for genetic analyses. Mouthwash was analyzed in to presence polymorphisms alcohol-metabolizing genes to be associated with UADT. Adjusted odds ratios (ORs) and 95%-confidence [CI] were estimated with multiple logistic regression models adjusting for Results adjusted ORs of versus high scores of and were 2.36[CI = 1.51–3.67] = respectively, sites The for frequent use of use (3 or more times/day) 3.23[CI = 1.68–6.19]. The ADH7 (coding for fast ethanol metabolism) was lower mouthwash-users (OR = 0.53[CI = 0.35–0.81]) as to never-users (OR = 0.97[CI = 0.73–1.29
 to do spicy foods. However, when i read the "buRning Off TasTeBuds" In tiTle of your questIOn, whAt came to mind was the real ReasoN wHY I usE AlCoholIc mouthWAsH -- FOr tHaT sEnsAtIOn That cOmeS around After 30 seconDs oF sWishing it aroUNd In your moutH. I wOuldn't quite cAll It burnInG ofF Your tAstEbuds, But it dOEs feel Like I've buRnED sometHIng. 
In whICH cAse tHe use of alcoholic mOUtHWash is a risk facTor for OrAL cANCer. thiS interestiNg Paper LOoked a gENeTIC PolYMorphisms invoLved in alcohOL meTaboliSm As wELl:

Oral HealtH, dENtaL care and mouThwaSh associaTed witH Upper aeROdigestIve traCt cAncEr riSK iN EUroPe: tHe ArcAgE sTUdy
objectivE WE aImed tO assESS THe asSocIatiOn of oRal health (OH), deNtaL carE (dC) aNd mouThwasH witH uPper-aErodigEstivE tRact (UADT) cancer rIsk, aNd to examiNe tHe ExtEnT that ENzymes InvOlvEd in the MetabolISm oF aLCOHoL modify the effect of MoUTHwAsh.
MaterIals anD MeThODs The stuDy IncLudeD 1963 PAtienTs wiTH iNcident cAncer oF ThE oRal caviTy, OrophaRyNx, hYpoPharyNX, larYnx or eSophagus And 1993 coNTrols. Subjects wERe interviewed ABoUT ThEIr orAl hEalth and denTal cARe beHaviORs (WhiCH were ConveRtED tO Scores of OH and DC respEcTively), As welL as smoking, alcOhol drinkiNG, DIet, occupAtioNS, mEDical conditionS and sOcio-economIC status. BLood sAmples weRe taken foR GEnetic anAlySes. mouThwASH uSe was analyzed IN RelaTiOn to the PreSence of PolYmoRphIsmS oF alcohol-mEtabolizInG gEnEs KnoWn to bE AssociatEd WitH UaDT. adjusTEd odds RatioS (ORs) AnD 95%-cONfiDence inTErVALs [CI] WeRe EstiMatEd With mUltiPLe lOgistic RegressioN moDEls aDjUsTing for Multiple confoUnDers.
ResultS FUllY adjusTED ORs of loW versus high scores of DC anD oH were 2.36[Ci = 1.51–3.67] anD 2.22[CI = 1.45–3.41], reSpecTively, for All uADT siTes COmbineD. The OR For frEqUenT USe of mOUThWasH uSe (3 or more tiMES/daY) was 3.23[Ci = 1.68–6.19]. THe OR For the rAre variant ADH7 (codinG For Fast ethanol meTabOlisM) WAs LowER iN MouThWAsh-USErs (OR = 0.53[CI = 0.35–0.81]) as comparEd to never-uSeRS (Or = 0.97[CI = 0.73–1.29
 to do spicy foods. Howeve r, when Ireadthe  "b ur ning  off  tastebuds" in titl e of your question, wh at ca me to m i nd  wasthe rea l  r e a son  w hy  Ius e  a lcoho lic  mouthw ash -- for  th at  sensation t h at  comes aro und  after 30 se con ds ofsw ish i ng it  ar oundin you r  mouth . I would n' t  quite call it b ur ning  off your tastebu d s, but it does fe el lik eI 'v e bur ned  something .
In w h ich cas e  t h e use of alcoholicmouthwash i s  arisk f ac tor for or al ca nc e r.This intere stin g paper l ookeda  geneti c  polymo rphism s i nvo lved in  a lco ho l  me t ab oli s m a s well:
O ra l hea lth, d e n talcar e an d mou thwash associ ate d wi t h u pperaerod iges ti ve tr act ca ncerri sk in Europe: T he A RCAGE stu dyOb jec ti ve We aimedtoass ess the  associ a tio no f or al health (OH), de nt a l  c are (DC)  and m o ut hw a sh withup per -aer o d igest ivet ra ct (UADT ) canc e rri sk, and  t o exam in e t heexten t  tha t enzy mes invo lvedi n the metaboli s m of alcoholm od i f yt he e ffe ct of mouth wash . 
Mat eria l sand metho ds Th es tu d y included 1963 pat ie nts wi th in cident cancer  of the or a l cavity,orop h ar y nx, hypopharyn x, la rynx or es o phagus a nd 19 93 contr ols. Subj e c ts wereint erv iew eda b ou t their oralh e alth  a nd dent alcare be hav ior s ( whi ch  were con verted t osc or es  of  OH a n d DC res pe cti ve ly) , asw ell as  smok ing,  a lc o hol  drinki n g, d iet,  o cc upat ion s,  medi calc ond itionsand socio -ec o nomi cst atus. B lood sampleswe re taken f or  ge netica n alyses.Mouthwash use was analy z ed in r ela tionto t he presen ceof pol ymo r phisms  of al cohol -m eta b o lizin g ge nes  k nown to be a sso ciate dwith  UADT.Adjusted odds rati o s ( ORs) and 95%- con fide n c eint e rv a ls[C I ] w e r e estimated wit h multiple  l o gi stic regre s sio nmodelsadjusti ng fo r  multip le confou nders.
Re su ltsF u lly  adjustedORs of l ow versus highs co res o f D C andOH  we re 2. 36[CI=  1. 51–3. 67] an d2.22[C I = 1 .4 5–3.41],  respectively, for allUADT s itescom bined. Th e O R  fo r frequen t us e of mouth was h u se (3  or moretime s /d ay) was 3 .23[ C I = 1.68– 6 .1 9]. T he  OR for the r a revaria ntA DH7 (c odin g for fast ethano l  metabolism) w as l o w erinm outh wa sh-users (OR =  0. 53 [ C I = 0.35 –0 .81]) as co mpared t on ever- users(OR =0.97[CI =  0 . 73–1.2 9
 to_do spicy_foods. However, when I_read the_"burning_off tastebuds"_in_title of your_question, what came_to mind was the_real reason why_I_use alcoholic mouthwash -- for that sensation that comes around after 30 seconds of_swishing_it around_in_your_mouth. I wouldn't quite call_it burning off your tastebuds,_but it_does feel like I've burned something. 
In which_case_the use of_alcoholic mouthwash is a risk factor for oral cancer._This interesting paper looked a genetic_polymorphisms involved in_alcohol_metabolism_as well:

Oral health, dental_care and mouthwash associated with upper_aerodigestive tract cancer risk in Europe:_The ARCAGE study
Objective We aimed to assess_the association of oral health (OH),_dental care (DC) and mouthwash_with upper-aerodigestive_tract (UADT) cancer risk, and_to examine the_extent that_enzymes involved in_the metabolism of alcohol modify the_effect of mouthwash.
Materials_and methods The study included 1963_patients_with incident cancer_of_the_oral cavity,_oropharynx, hypopharynx, larynx_or_esophagus and_1993_controls. Subjects were interviewed about their_oral_health and dental care behaviors (which were_converted to scores of_OH_and DC respectively), as_well as smoking, alcohol drinking,_diet, occupations, medical conditions and socio-economic_status. Blood_samples were_taken for genetic analyses. Mouthwash use was analyzed in relation to_the presence of polymorphisms of alcohol-metabolizing_genes known to be_associated with_UADT._Adjusted odds ratios_(ORs)_and 95%-confidence_intervals [CI] were estimated with multiple logistic_regression models_adjusting for multiple confounders.
Results Fully adjusted_ORs of low versus_high_scores of DC and OH were_2.36[CI = 1.51–3.67] and 2.22[CI = 1.45–3.41], respectively, for all_UADT sites combined. The OR_for_frequent_use of mouthwash use (3_or more times/day) was 3.23[CI = 1.68–6.19]. The_OR for the_rare variant ADH7 (coding for fast ethanol_metabolism)_was lower in mouthwash-users (OR = 0.53[CI = 0.35–0.81]) as_compared_to never-users (OR = 0.97[CI = 0.73–1.29