In his lifetime, Wright designed about 450 buildings, 380 of which remain standing, according to Barbara Gordon, the executive director of the Frank Lloyd Wright Building Conservancy, a nonprofit organization in Chicago.

While people are most familiar with his public projects like the Guggenheim Museum, or his showcase houses like Fallingwater in western Pennsylvania, Wright designed more than 300 houses, most of which incorporated natural surroundings and materials into a design of clean, angular lines, with an emphasis on public spaces.

About 45 Wright properties have changed hands in the last five years, Ms. Gordon said. The process is not easy, with many going on and off the market over many years, as owners try to find buyers willing to assume the responsibility while appreciating what they are getting.

“These houses may not have the number of bedrooms or baths and the large, open kitchens that people demand now,” Ms. Gordon said, “but the livability comes with the warmth and light, and that special feel you have being in these homes.”

Here are the stories of five Wright houses that have recently changed hands or are now on the market.

A Tough Sale in an Obscure Location

Fred Taber knew he had his work cut out for him in late 2012 when he was approached to sell the three-bedroom Eppstein House in Galesburg, Mich. One of four Wright houses built for scientists from Upjohn in a 70-acre compound known as the Acres, the 2,250-square-foot house had been largely neglected for more than 15 years. The roof leaked, the boiler had rusted out, the 60-year-old wiring needed updating, and the pool surrounded by a chain-link fence was an eyesore.