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fabba8e7-51aa-4705-90cf-b310d23a59a7
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Dental
{ "Correct Answer": "Type I alpha error", "Correct Option": "A", "Options": { "A": "Type I alpha error", "B": "Type II beta error", "C": "Gamma error", "D": "All of the above" }, "Question": "True about the statement is: When null hypothesis is rejected when it is true?" }
null
3118ef6a-713b-4bc5-908e-6bab3766e8bc
Myosin is thick filament. All others  in the options are thin filaments.
Physiology
{ "Correct Answer": "Myosin", "Correct Option": "C", "Options": { "A": "Actin", "B": "Troponin", "C": "Myosin", "D": "Tropomyosin" }, "Question": "Thin filament consists of all except:" }
Central Nervous System
43746273-1b76-4c58-97ac-7de0af6fdab0
Tay-Sachs disease is a lethal, autosomal recessive disorder caused by an inborn deficiency of hexosaminidase A, which permits the accumulation of ganglioside GM1 in CNS neurons. The disease is fatal in infancy and early childhood. Retinal involvement increases macular transparency and is responsible for a cherry-red spot in the macula. On histologic examination, lipid droplets are seen in the cytoplasm of distended nerve cells of the CNS and peripheral nervous system. Electron microscopy reveals the lipid within lysosomes in the form of whorled "myelin figures." Swollen neurons that exhibit marked vacuolization of the perikaryon and contain lysosomes filled with lipid can also occur in other lipid-storage diseases (e.g., Gaucher disease, Niemann-Pick disease). The other diseases do not produce such neuronal changes.Diagnosis: Tay-Sachs disease
Pathology
{ "Correct Answer": "Tay-Sachs disease", "Correct Option": "D", "Options": { "A": "AL amyloidosis", "B": "Hurler syndrome", "C": "Phenylketonuria", "D": "Tay-Sachs disease" }, "Question": "A 1-year-old boy presents with a delay in motor development. Progressive muscle weakness and blindness ensue, and the patient dies within a year. The brain at autopsy shows swollen neurons that contain numerous lysosomes filled with lipid. Which of the following is the most likely diagnosis?" }
null
3589876c-919b-4ce7-ba8b-598a71343f7d
Ans. is 'b' i.e., E. coli o E. coli & streptococcus agalactie (group B streptococci) are the two most common cause of neonatal sepsis and meningitis.
Pediatrics
{ "Correct Answer": "E. coli", "Correct Option": "B", "Options": { "A": "Staphylococcus", "B": "E. coli", "C": "H. influenze", "D": "Pneumococcus" }, "Question": "Most common cause of neonatal meningitis-" }
null
fa080eec-d8c0-4bbc-9d03-14288e46a80e
null
Medicine
{ "Correct Answer": "Liver", "Correct Option": "B", "Options": { "A": "Lungs", "B": "Liver", "C": "Lymph nodes", "D": "Skin" }, "Question": "Primary complex in which of the following sites suggest congenital tuberculosis -" }
null
69f8092f-1fd4-489f-818f-72c1bd562463
Conjugation Bacterial conjugation is the transfer of genetic material between bacteria through direct cell to cell contact or through a bridge- like the connection between two cells. Conjugation is a process whereby a donor (male) bacterium makes physical contact with a recipient (female) bacterium. Donor status is determined by the presence of plasmid. This plasmid codes for specialized fimbria (sex pilus) and for self-transfer. Sex pilus (conjugation tube) helps in transfer of genetic material from male bacterium to female bacterium. The plasmid is known as transfer factor (sex factor or fertility factor). The plasmid may be R factory which codes for transferrable multiple drug resistance. The DNA of the plasmid replicates during transfer so that each bacterium receives a copy → Recipient becomes a donor and the donor retains its donor status.
Microbiology
{ "Correct Answer": "Conjugation", "Correct Option": "C", "Options": { "A": "Transduction", "B": "Transformation", "C": "Conjugation", "D": "Vertical transmission" }, "Question": "R-factor in bacteria is transferred by" }
null
21ec65bc-a0f9-4c62-b8b0-0d3dc5f8b331
D i.e. Bicarbonate Transpo of CO2 in the form of bicarbonate ions accounts for approximately 70% of transpoed carbon dioxide from the tissues to lungs Q. So CO2 is transpoed as plasma HCO3 - > RBC > HCO3- > Carbamino compound > dissolved CO2 Q &Transpo of Carbon Dioxide Carbon dioxide is transpoed in the blood as: HCO3- (70%) > carbamino compounds (23%) > dissolved CO2 (7%) Chloride Shift/ Hamburger Phenomenon When the negatively charged (HCO3-) bicarbonate ions move out of red blood cell into the plasma, to maintain the electrolytic equilibrium the negatively charged chloride ions move into the Red blood Cells from plasma (In plasma plenty of sodium chloride is present). This process is mediated by band 3 membrane protein Chloride shift occurs in: 1 secondQ Hematocrit of venous blood is: greater (by 3%)than that of aerial bloodQ PH of venous blood (7.36) is lower than that of aerial blood (7.40)Q * For each CO2 molecule added to RBC there is increase in one osmotically active paicle in cell either HCO3- or CI-. So RBC take up water & swell. For this reason plus a fact that some aerial fluid returns lymphatics rather than the veins, the hematocrit of venous blood is 3% greater than aerial bloodQ. Amount of 02 enters the body/min = 250 inVininQ Amount of CO2 excreted by lung/ min = 200 inVininQ (288 L/day)Q * CO2 is 20 times more soluble than 02
Physiology
{ "Correct Answer": "Bicarbonate", "Correct Option": "D", "Options": { "A": "Dissolved CO2.", "B": "Carbonic Acid.", "C": "Carbamino-hemoglobin.", "D": "Bicarbonate" }, "Question": "CO2 is primarily transpoed in the aerial blood as" }
DNB 2018
f09c1184-52d9-481d-97be-018d1a798945
The sequence of SPECIFIC events of Pubeal events in girls is thelarche, pubarche, linear growth spu, menarche. Please note: This is not to confuse with accelarated general physical growth which is the first event in pubey Pubey Specific events in girls Events in boys 1st Thelarche Testicular enlargement 2nd Pubarche Penile enlargement & pubic hairs 3rd Linear Growth,Height, spu Linear Growth spu 4th Menarche Axillary hair and facial hairs In girls, pubeal development typically takes place over 4.5 years. The first sign of pubey is accelerated growth, and breast budding is usually the first recognized pubeal change, followed by the appearance of pubic hair, peakgrowth velocity, and menarche.... Novaks Gyne
Gynaecology & Obstetrics
{ "Correct Answer": "Thelarche, Pubarche, linear growth spu, Menarche,", "Correct Option": "A", "Options": { "A": "Thelarche, Pubarche, linear growth spu, Menarche,", "B": "Pubarche, Thelarche, Menarche, linear growth spu", "C": "Pubarche, Menarche, Thelarche, linear growth spu", "D": "Menarche, Thelarche, Pubarche, linear growth spu" }, "Question": "What is the sequence of development of pubey in girls ?" }
Penicillin & Cephalosporin
5fb4705e-3b44-41da-ad08-25688404bdab
Ans. is 'b' i.e. epinephrine injection Urticaria, swelling of lips, hypotension and bronchospasm within 5 minutes of i.v penicillin suggests anaphylactic reaction. It's a major problem with the use of penicillin.The t/t of choice for anaphylaxis is i.v epinephrine.
Pharmacology
{ "Correct Answer": "Epinephrine inj.", "Correct Option": "B", "Options": { "A": "chlorphenitramine inj.", "B": "Epinephrine inj.", "C": "High dose hydrocortisone tablet", "D": "nebulised salbutamol" }, "Question": "A 70 - year- old man was administered penicilline intravenously. Within 5 minutes, he developed genralised urticaria, swelling of lips, hypotension and bronchospasm. The first choice of treatment is to administer:" }
null
663ce243-7b00-468a-b2cb-aea89130cc9b
Ans. is 'b' i.e., 1700 ml Fluid requirment in a child o It depends on the weight of a child :- Weight Water requirments < 10 kg o 100 ml/kg/day 10-20 kg o 100 ml / kg / day for first 10 kg (i.e. 1000 ml) + 50 ml / kg / d for every kg above 10 kg. >20 kg o 100 ml/kg/day for first 10 kg (i.e. 1000 ml) + 50 ml / kg / d for next 10 kg (i.e. 500 ml) + 20 ml / kg / d for every kg above 20 kg. o The child in question has weight of 30 kg. o So, fluid requirment will be :- i) 1000 ml for first 10 kg Plus ii) 500 ml for 10-20 kg Plus iii) 200 ml (20 x 10) for 20-30 kg o Total requirment will be 1700 ml.
Pediatrics
{ "Correct Answer": "1700 ml", "Correct Option": "B", "Options": { "A": "1300 m1", "B": "1700 ml", "C": "2000 ml", "D": "2500 ml" }, "Question": "Daily water requirement in child weighing 30 kgs, height 123 m and BSA of 1 m2 is-" }
General anatomy
68f71e37-a2a5-44ef-9139-71914b863fa4
.
Anatomy
{ "Correct Answer": "Methylphenidate", "Correct Option": "A", "Options": { "A": "Methylphenidate", "B": "Modafinil", "C": "Amitriptyline", "D": "Adrenaline" }, "Question": "Drug of choice for ADHD is" }
Abdominal Radiography
07869051-9b4b-47c8-8f93-1b9828078a28
Ans. is 'd' i.e., All of the above o Double bubble sign is seen in duodenal atresia, duodenal web, deudenal stenosis, Ladd's band, Annular pancreas, Malrotation of gut, preduodenal vein.Single Bubble signCongenita] hypertrophic pyloric stenosisDouble Bubble signDuodenal atresiaDuodenal webDuodena] stenosisLadd's bandAnnular pancreasMalrotation of gutPreduodenal veinTriple Bubble signJejunal or proximal ileum atresiaMultiple Bubble signIleal atresia
Radiology
{ "Correct Answer": "All of the above", "Correct Option": "D", "Options": { "A": "Ladd's band", "B": "Annular pancreas", "C": "Duodenal atresia", "D": "All of the above" }, "Question": "Double bubble sign is seen in -" }
Schizophrenia Spectrum and Other Psychotic Disorders
b9aac52e-05c8-4feb-9869-ab57c9704bdd
The history is suggestive of delusion of persecution (fear that schoolmates may "harm" him) and delusion of reference (belief that classmates laugh at him and talk about him). Had they not used the term "harm" and "scared" a diagnosis of social anxiety disorder could have been enteained.
Psychiatry
{ "Correct Answer": "Schizophrenia", "Correct Option": "D", "Options": { "A": "Anxiety disorder", "B": "Manic depressive psychosis (bipolar disorder)", "C": "Adjustment reaction", "D": "Schizophrenia" }, "Question": "A 16 year old boy does not attend school because of the fear of being harmed by school mates. He thinks that his classmates laugh at him and talk about him. He is even scared of going out of the market. He is most likely suffering from:" }
Substance abuse
abd192eb-0adf-49cf-ac78-e01855cfbce7
LSD is a type of hallicinogen LSD means lysergic acid diethylamide LSD was introduced and first used by ALBE HOFFMANNBad trip is seen with LSD and cannabis but common with LSD Ref: Essentials of postgraduate psychiatry By JN Vyas 1st ed Pg 330-336
Psychiatry
{ "Correct Answer": "LSD", "Correct Option": "B", "Options": { "A": "Cannabis", "B": "LSD", "C": "None", "D": "Both" }, "Question": "Bad trip is seen with which of the following drugs?" }
Childhood tumors
9efce15d-8682-4927-b158-6927e4fd276e
WTl is the best characterized Wilms tumor gene. It is located at chromosome llp13 and encodes for a transcription factor that is critical for normal development of kidneys and gonads. WT2 is localized to a cluster of genes at llpl5. Reference: Essential paediatrics; O.P.Ghai; Childhood Malignancies; Page no: 617
Pediatrics
{ "Correct Answer": "11", "Correct Option": "A", "Options": { "A": "11", "B": "13", "C": "18", "D": "22" }, "Question": "Chromosome involved in Wilm's tumor is" }
S.T.D.
79efe49b-5816-4588-a0d7-4f9433db2335
Ans. is 'c' i.e., LGV * 'Groove sign of Greenblatt' is pathognomonic of LGV (secondary stage) - when inguinal lymph nodes are enlarged, they are separated by Poupart's ligment, producing a groove.Lymphogranuloma venerum (lymphogranuloma inguinale)* LGV is caused by chlamydia trachomatis, serotypes LI, L2, L3. Serotype L2 is the most common cause. The clinical course of LGV consist of following three stages : -i) First stage (Primary LGV): - Self limited, Single, asymptomatic, painless, non bleeding genital ulcer.ii) Secondary stage: - Painful inguinal lymphadenopathy (Remember - Ulcer is painless but lymphadenopathy is tender & painful). Swollen lymph nodes coalesce to form bubos, i.e., matted lymph nodes. Buboes may rupture to form discharging sinus.# Groove's sign - Enlarge lymph nodes both above and below inguinal ligament.iii) Tertiary LGV (genitorectal syndrome): - Characterized by proctocolitis.Complications of LGV* Esthiomene - Enlargement, thickening and fibrosis of labia.* Elephantiasis of the genitals* Rectal stricture* Systemic - Arthritis, pneumonitis, Perihepatitis
Skin
{ "Correct Answer": "LGV", "Correct Option": "C", "Options": { "A": "Syphilis", "B": "Dermatomyositis", "C": "LGV", "D": "SLE" }, "Question": "Groove sign is seen in-" }
Fluid and electrolytes
5a2c6025-f375-422b-b787-a56ec6b23bca
The combination of hyperkalemia and hyperchloremic metabolic acidosis is often present, even at earlier stages of CKD (stages 1-3).In patients with diabetic nephropathy or in those with predominant tubulointerstitial disease or obstructive uropathy; this is a non-anion-gap metabolic acidosis.
Medicine
{ "Correct Answer": "A", "Correct Option": "A", "Options": { "A": "A", "B": "Diarrhoea", "C": "DKA", "D": "Dehydration" }, "Question": "Hyperchloremic acidosis is seen in-" }
null
8f10721c-3ef4-4c3a-a6eb-77b8da9a9cf0
Ans. is 'a' i.e. Lead time
Social & Preventive Medicine
{ "Correct Answer": "Lead time", "Correct Option": "A", "Options": { "A": "Lead time", "B": "Screening time", "C": "Serial interval", "D": "Generation time" }, "Question": "A patient with cervix cancer is missed by a screening test and later diagnosed with advanced disease. This time interval is called ?" }
null
13807e41-a89f-4da3-ab6b-7a64ec0fdb2e
The internal iliac aery divides into an anterior and a posterior trunk near the greater sciatic foramen.Branches of ANTERIOR TRUNKUmbilical aeryObturator aeryUterine aeryInferior vesical and vaginal aery (females)Middle rectal aeryInternal pudendal aeryInferior gluteal aeryBranches of POSTERIOR TRUNKIliolumbar aeryLateral sacral aerySuperior gluteal aery
Anatomy
{ "Correct Answer": "Internal iliac aery", "Correct Option": "C", "Options": { "A": "External iliac aery", "B": "Inferior vesical aery", "C": "Internal iliac aery", "D": "Inferior epigastric aery" }, "Question": "The internal pudendal aery arises from which of the following aeries?" }
G.I.T
502328ba-6339-4d52-a737-4f7b57b333b5
Serum IgA increased in - Alcoholic cirrhosis Serum IgM increased in -Primary biliary cirrhosis (Ref: Clin Exp Immunol.2009 Oct; 158(1): 115-124, Liver.1984 Jun;4(3): 214-8)
Pathology
{ "Correct Answer": "Alcoholic cirrhosis", "Correct Option": "B", "Options": { "A": "Alcoholic hepatitis", "B": "Alcoholic cirrhosis", "C": "Microvescicular fatty change", "D": "Macrovesicular fatty change" }, "Question": "Increased Ig A levels are seen in" }
Targeted Anticancer Drugs and Immunosuppressants
7217ed20-27bf-4bf1-84d2-6ddb18022234
Rituximab is a monoclonal antibody against CD20. It is used for treatment of: Non-Hodgkin lymphoma Chronic lymphoid leukemia Rheumatoid ahritis SLE Auto-immune hemolytic anemia Idiopathic thrombocytopenic purpura
Pharmacology
{ "Correct Answer": "Non-Hodgkin's lymphoma", "Correct Option": "A", "Options": { "A": "Non-Hodgkin's lymphoma", "B": "Gastrointestinal Stromal Tumors", "C": "Chronic Myeloid Leukemia", "D": "Acute Myeloid Leukemia" }, "Question": "Rituximab is a monoclonal antibody used for treatment of:-" }
Intestinal obstruction
6b60772d-c91f-450a-92a3-4c26c3c8112a
Types of Intussusceptions (in decreasing order) Ileocolic (77%) Ileo-ileo-colic (12%) Ilioileal (5%) Colocolic (2%): MC in adults Multiple (1%) Retrograde (0.2%)
Surgery
{ "Correct Answer": "Multiple", "Correct Option": "A", "Options": { "A": "Multiple", "B": "Colocolic", "C": "Ileoileal", "D": "Ileoileocolic" }, "Question": "The least common type of intussusceptions is:" }
Nose and paranasal sinuses
33d6780f-f9b8-4528-bbd9-2b6c065ada10
Sinuscopy is a method of Endoscopic sinus observation or surgery using Nose telescope. It involves the evaluation of nasal and sinus passages using the endoscope called Sinuscope. The Sinuscope has a narrow tube with a built-in camera so that the physician can see the internal details of the sinuses. By observing the sinus, it is possible to diagnose the problems and treat properly.
ENT
{ "Correct Answer": "Sinuscopy", "Correct Option": "C", "Options": { "A": "X- ray PNS", "B": "Proof puncture", "C": "Sinuscopy", "D": "Transillumination test" }, "Question": "Most definitive diagnosis of sinusitis is by" }
null
2d906c4a-16b9-494d-83d6-d6831dea8413
Vascular malformation (VM) in bone occurs more frequently than the central hemangioma (CH) of bone. Some 35% of VMs occur in bone, whereas CHs of bone are rare. The CH of bone is a benign tumor that rarely occurs in the jaws; it occurs more frequently in the skull and vertebrae. It may be congenital or traumatic in origin and may be difficult to differentiate from VM. The usual complaint of a patient with a VM or CH is of a slow-growing asymmetry of the jaw or localized gingival bleeding. Numbness and tenderness or pain may also be described. This solitary tumor is found approximately twice as often in female patients, and about 65% occur in the mandible. Some tumors demonstrate pulsation and bruits. Paresthesia is occasionally a feature.
Radiology
{ "Correct Answer": "Vascular malformation", "Correct Option": "A", "Options": { "A": "Vascular malformation", "B": "Cherubism", "C": "Eosinophilic granuloma", "D": "Brown tumor" }, "Question": "An 18 year old male patient presented to the clinic with pain and swelling in the lower jaw. Intraoral examination\nrevealed localized gingival bleeding in the right posterior region. On palpation, pulsations can be appreciated. Lesions are also appreciated on the frontal bone on a radiograph. Which condition is present in this patient?" }
Misc.
224684fc-43a1-4ea2-b3c4-2137a5b092a9
Ref: Bailey and Love, 26th edition, P 868Most common anterior mediastinum tumor is thymoma. Choice B is seen in posterior mediastinum. Choice C and D are found in middle mediastinum.
Pathology
{ "Correct Answer": "Thymoma", "Correct Option": "A", "Options": { "A": "Thymoma", "B": "Neurofibroma", "C": "Pericardial cyst", "D": "Bronchogenic cyst" }, "Question": "Most common anterior mediastinal tumor?" }
Systemic histology
a11d6f28-7147-4a50-9745-41499c36a2b8
Anatomical unit of liver - Hepatic Lobule Functional unit of liver- Liver Acinus
Anatomy
{ "Correct Answer": "Liver Acinus", "Correct Option": "C", "Options": { "A": "Hepatocytes", "B": "Poal Tracts", "C": "Liver Acinus", "D": "Hepatic Lobule" }, "Question": "Functional unit of Liver is" }
Introduction to Forensic Medicine and Medical Jurisprudence
d6ed9456-f50e-4add-af7e-74ff49545af6
Ans: a (320 IPC) Ref: Reddy, 21st ed, p. 244Grievous hurt is defined under IPC 320Some important IPC'sIPC 375 - definition of rapeIPC 376 - punishment of rapeIPC 320 - definition of grievous heartIPC 84 - deals with the criminal responsibility of insaneIPC304A - deals with criminal negligenceIPC 304B - dowry deathIPC 300 - defines murderIPC 299 - defines culpable homicideIPC 302 - punishment of murderIPC 304 - punishment of culpable homicide
Forensic Medicine
{ "Correct Answer": "320IPC", "Correct Option": "A", "Options": { "A": "320IPC", "B": "318 IPC", "C": "321 IPC", "D": "375 IPC" }, "Question": "Grievous hurt is defined under:" }
General Considerations - Definition, Classification, Pathogenesis
6e90b215-167a-448f-89c5-4d05d26c9000
Ans. is 'a' i.e., Raised intraocular pressure The most common risk factor known is increased intraocular pressure (lOP)o Glaucoma is a group of eye diseases causing optic nerve damage i.e., glaucoma is a chronic, progressive optic neuropathy caused by a group of ocular conditions which lead to damage of optic nerveo Optic neuropathy in glaucoma results in a characteristic appearance of optic disc and a specific pattern of irreversible visual field defects, called glaucomatous changes. It is worth noting that raised IOP without optic neuropathy is not referred to as glaucoma, it is simply called ocular hypertension.So, glaucoma is a type of optic neuropathy, which is usually caused by increased IOP.
Ophthalmology
{ "Correct Answer": "Raised intraocular pressure", "Correct Option": "A", "Options": { "A": "Raised intraocular pressure", "B": "Raised intracranial Pressure", "C": "Intraocular infection", "D": "Orbital mass" }, "Question": "Glaucoma is caused by -" }
obstetrics,pediatrics and geriatrics
b93b305f-5080-4b89-b598-f20947050b76
Rate of increase of height and weight is the best measure for nutritional status of a child. REF. PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICAL 21ST EDITION. 500,501
Social & Preventive Medicine
{ "Correct Answer": "Rate of increase of height and weight", "Correct Option": "C", "Options": { "A": "Mid arm circumference", "B": "Head circumference", "C": "Rate of increase of height and weight", "D": "Chest circumference" }, "Question": "Best indicator for nutritional status for a child is -" }
null
c4a71346-9a2b-4446-bb03-427398f957b8
null
Pediatrics
{ "Correct Answer": "RSV", "Correct Option": "A", "Options": { "A": "RSV", "B": "H.influenza", "C": "Pneumococcus", "D": "Streptococcus" }, "Question": "Aerosolized ribavirin is used in the treatment of bronchiolitis with –" }
null
5490fe0e-173c-482e-805b-0482ba08204d
PCR is an in vitro method for the polymerase-directed amplification of specific DNA sequences using two oligonucleotide primers that hybridize to opposite strands and flank the region of interest in the target DNA. The specificity and yield in amplifying a paicular DNA fragment by PCR reaction is affected by the proper setting of the reaction parameters (e.g., enzyme, primer, and Mg2+ concentration, as well as the temperature cycling profile). Ref: Feng X., Lin X., Brunicardi F.C. (2010). Chapter 15. Molecular and Genomic Surgery. In F.C. Brunicardi, D.K. Andersen, T.R. Billiar, D.L. Dunn, J.G. Hunter, J.B. Matthews, R.E. Pollock (Eds), Schwaz's Principles of Surgery, 9e.
Biochemistry
{ "Correct Answer": "Magnesium", "Correct Option": "C", "Options": { "A": "Calcium", "B": "Lithium", "C": "Magnesium", "D": "Sodium" }, "Question": "Amplification of DNA uses the polymerase chain reaction (PCR) technique. Cation used in PCR is:" }
null
5aaf7feb-8094-4590-9a67-2345167bf66c
C i.e. It has indolent course and good prognosis
Skin
{ "Correct Answer": "It has a indolent course and good prognosis", "Correct Option": "C", "Options": { "A": "It is the most common skin lymphoma", "B": "Pautriers micro abscesses are common", "C": "It has a indolent course and good prognosis", "D": "It presents with diffuse erythroderma." }, "Question": "Which of the following statements about mycosis fungoides is not true?" }
Parasitology
9a778c55-b44d-46f9-a387-07f4764a5ed4
Ans. is 'a' i.e., Tick Babesiao Babesiosis is a protozoan disease caused by two species of Babesia : Babesia microti and Babesia divergens.o It is transmitted by loxdid tick.o Babesia infects the RBCs and resides inside the RBCs ( intraerythrocytic). Intraery throcytic infection of Babesiosis is characterised by maltese cross. Maltese cross is a characteristic arrangement of parasites within the erythrocytes - Parasites within erythrocytes are arranged such that pointed ends of four parasites come in contact thereby giving a tetrad configuration resembling a maltese cross. Tetrad forms or 'Maltese cross' appearance is considered pathognomic of Babesiosis.o Clinically Babesiosis presents with chills, fever, mild hepatosplenomegaly, and mild hemolytic anemia,o Treatment includes Atovaquone plus azithromycin or quinine plus clindamycin.o Babesiosis can easily be confused with P. falciparum malaria.Following two features distinguish Babesiosis from malariaPresence of maltese cross in Babesiosis (absent in malaria)Absence of pigment Hemozoin in Babesiosis (present in malaria)Note - Maltese cross is also seen in cryptococcus and aspergillus.
Microbiology
{ "Correct Answer": "Tick", "Correct Option": "A", "Options": { "A": "Tick", "B": "Mites", "C": "Flea", "D": "Mosquito" }, "Question": "Babesiosis is transmitted by -" }
null
cf77282d-7a63-458f-8dfb-a471cd7534ed
Answer is C (MR) Mitral Regurgitation is not a feature of Aoic dissection Aoic Regurgitation and Pericardial Tamponade may be seen in proximal dissection Hemopericardium and cardiac tamponade may complicate a dissection involving the ascending aoa (type A lesion with retrograde dissection): Acute Aoic Regurgitation (AR) is an impoant and common complication of proximal dissection - Acute Myocardial Ischemia may be associated with Aoic dissection 'Bowel Ischemia, hematuria and myocardial Ischemia have all benn observed with Aoic dissection'
Medicine
{ "Correct Answer": "MR", "Correct Option": "C", "Options": { "A": "Pericardial effusion", "B": "AR", "C": "MR", "D": "AMI" }, "Question": "Manifestation of Acute Dissection include all of the following, Except:" }
null
60506fc9-20d7-414b-a85f-de78719c10fa
Hepatitis is the most common preceding infection, and post hepatitis marrow failure accounts for about 5% of etiologies in most series. Patients are usually young men who have recovered from a bout of liver inflammation 1 to 2 months earlier; the subsequent pancytopenia is very severe. The hepatitis is seronegative (non-A, non-B, non-C, non-G) and possibly due to a novel, as yet undiscovered, virus. Ref: Harrison's principle of internal medicine 17th edition, chapter 102.
Medicine
{ "Correct Answer": "Hepatitis", "Correct Option": "A", "Options": { "A": "Hepatitis", "B": "Infective carditis", "C": "Pyelonephritis", "D": "Meningitis" }, "Question": "Pancytopenia is most common after:" }
Anti Microbial
99f5d0ae-9123-44a6-a1c1-7eda87aba41b
Ans. is 'd' i.e., Cefuroxime Third generation cephalosporins include Parenteral OralCefotaxime - CefiximeCeftizoxime - Cefpodoxime proxetilCeftriaxone - CefdinirCeftazidime - Ceftibuten Cefoperazone Also knowFourth generation cephalosporinsCefepimeCefaparole
Pharmacology
{ "Correct Answer": "Cefuroxime", "Correct Option": "D", "Options": { "A": "Ceftriaxone", "B": "Cefotaxime", "C": "Ceftizoxime", "D": "Cefuroxime" }, "Question": "Which is NOT a third generation Cephalosporin" }
null
19514f92-0244-4363-9913-03e861548b72
B i.e. 1 - 2 hours
Forensic Medicine
{ "Correct Answer": "1-2 hrs", "Correct Option": "B", "Options": { "A": "1/2-1 hrs", "B": "1-2 hrs", "C": "3-6 hrs", "D": "12 hrs" }, "Question": "Rigor moritis devolops ..... after death :" }
null
c7bc24f2-6ab4-4913-9437-10c2ccbcbb0b
Answer is D (Pansystolic murmur)
Medicine
{ "Correct Answer": "Pansystolic murmur", "Correct Option": "D", "Options": { "A": "High-pitched decrescendo diastolic murmur.", "B": "Soft, low pitched mid distolic rumbling murmur.", "C": "Mid-systolic ejection flow murmur", "D": "Pansystolic murmur" }, "Question": "All of the following murmurs may be heard in patients with aoic regurgitation except:" }
Ultrasonography, CT, and MRI
12725f6c-3ce1-4ccc-9657-7c7e58a9aa6e
Ans: A (CT ?) Ref: Harrison !v Principles of internal medicine.18th edition.Explanation:CT is the best technique to detect pericardial calcification; however, overpenetrated films, conventional tomography, fluoroscopy, and MRI may be helpful.Plain radiographs have poor sensitivity for detection of coronary calcification and have a reported accuracy as low as 42%High-quality mammography is the best diagnostic tool for the identification of breast calcifications.
Radiology
{ "Correct Answer": "CT", "Correct Option": "A", "Options": { "A": "CT", "B": "MRI", "C": "X-ray", "D": "USG" }, "Question": "Best investigation to see calcification is:" }
Anesthesia Circuit
8fe8bc4d-d411-4281-98fa-f74eaf59212a
A nasal cannula is generally used wherever small amounts of supplemental oxygen are required, without rigid control of respiration, such as in oxygen therapy. Most cannulae can only provide oxygen at low flow rates--up to 5 litres per minute (L/min)--delivering an oxygen concentration of 28-44%. Rates above 5 L/min can result in discomfo to the patient, drying of the nasal passages, and possibly nose bleeds (epistaxis). Also with flow rates above 6 L/min, the laminar flow becomes turbulent and the oxygen therapy being delivered is only as effective as delivering 5-6 L/min. The nasal cannula is often used in elderly patients or patients who can benefit from oxygen therapy but do not require it to self respirate. These patients do not need oxygen to the degree of wearing a non-rebreather mask. It is especially useful in those patients where vasoconstriction could negatively impact their condition, such as those suffering from strokes.
Anaesthesia
{ "Correct Answer": "0.44", "Correct Option": "D", "Options": { "A": "1", "B": "0.6", "C": "0.2", "D": "0.44" }, "Question": "Maximum FiO2 which can be given through a nasal oxygen catheter:-" }
null
a416ccba-a1a3-4c20-8456-e93759bd8b61
null
Pathology
{ "Correct Answer": "manifests with blue sclera which are pathognomonic of this disease", "Correct Option": "B", "Options": { "A": "Is a sex-linked disorder of bones that develop in cartilage", "B": "manifests with blue sclera which are pathognomonic of this disease", "C": "May be associated with deafness", "D": "Has associations with amelogenesis imperfecta" }, "Question": "Osteogenesis imperfecta" }
General anatomy
8cd5014f-869e-4dc2-ad05-401b60b7ad26
Neuropraxia is due to compression of the nerve,the nerve conduction velocity is increased. It has good prognosis Ref:Guyton and Hall textbook of medical physiology 12th edition,page number:74,75,76
Anatomy
{ "Correct Answer": "Both", "Correct Option": "C", "Options": { "A": "Prolongatinon of conduction velocity", "B": "Good prognosis", "C": "Both", "D": "None" }, "Question": "True about neuropraxia" }
Other topics and Adverse effects
7b3a5354-653e-4558-b990-061ced67975b
Ref-KDT 6/e p146 Stimulation of Alpha 2 receptors located on ciliary epithelium reduces secretion of aqueous humor.
Anatomy
{ "Correct Answer": "Alpha 2 receptor", "Correct Option": "D", "Options": { "A": "Beta 1 receptor", "B": "Beta 2 receptor", "C": "M2 receptor", "D": "Alpha 2 receptor" }, "Question": "Agonistic action at which of the following adrenergic receptor result in the reduction of excess secretion" }
Infectious Lung Disease: Pneumonia
2e01c33d-078f-406c-b2a9-7d91a0c7e179
Typical Pneumonia Atypical pneumonia -Bacterial etiology -Alveolar exudate + neutrophilic infilitration -C/F - High grade fever productive Cough Pleuritis Signs of consolidation -Non - bacterial etiology (e.g. Virus) -Interstitial tissue inflammation -C/F- Low grade fever Dry cough Malaise no signs of consolidation
Pathology
{ "Correct Answer": "Predominance of alveolar exudate", "Correct Option": "B", "Options": { "A": "Presence of interstitial inflammation", "B": "Predominance of alveolar exudate", "C": "Bronchiolitis", "D": "Multinucleate giant cells in the bronchiolar wall" }, "Question": "All of the following features are seen in the viral pneumonia except:" }
Radiology Q Bank
d586e17c-d764-4a7b-8d14-d3bc8bdc1c21
Superior rib notching -Polio -Restrictive lung disease -Neurofibromatosis -Connective tissue disease -Osteogenesis imperfecta Inferior rib notching -Thrombosis of aoa -Coarctation of aoa -Blalock Taussig shunt -Occlusion of subclan aery -Pulmonary AV malformation Both Superior and inferior rib notching -NF-1 -Hyperparathyroidism
Radiology
{ "Correct Answer": "NF-1", "Correct Option": "A", "Options": { "A": "NF-1", "B": "Blalock Taussig shunt", "C": "SVC occlusion", "D": "Coarctation of aoa" }, "Question": "Which of the following causes BOTH superior and inferior rib-notching in a chest radiograph?" }
Stomach & Duodenum
977cfd21-baf1-4a64-a125-378d92fbdafb
-All patients with gastrinoma have an elevated gastrin level, and hypergastrinemia in the presence of elevated basal acid output (BAO) strongly suggests gastrinoma. -Patients with gastrinoma usually have a BAO >15 mEq/h or >5 mEq/h if they have had a previous procedure for peptic ulcer. -Acid secretory medications should be held for several days before gastrin measurement, because acid suppression may falsely elevate gastrin levels. 1). The diagnosis of Zollinger-Ellison syndrome (ZES) is confirmed by the secretin stimulation test. An intravenous (IV) bolus of secretin (2 U/kg) is given and gastrin levels are checked before and after injection. - An increase in serum gastrin of 200 pg/mL or greater suggests the presence of gastrinoma. Patients with gastrinoma should have serum calcium and parathyroid hormone levels determined to rule out multiple endocrine neoplasia type 1 (MEN1) and, if present, parathyroidectomy should be considered before resection of gastrinoma.
Surgery
{ "Correct Answer": "Secretin stimulation test", "Correct Option": "D", "Options": { "A": "Fasting serum gastrin", "B": "Computed tomography (CT) scan", "C": "Endoscopy", "D": "Secretin stimulation test" }, "Question": "The most accurate diagnostic test for Zollinger-Ellison syndrome (ZES) is" }
Communicable diseases
10957cbd-4a0e-4d84-afef-f08ee2a1cf1a
<p> It is the average number of each species per rat/rodent. Reference:Park&;s textbook of preventive and social medicine,K.Park,23rd edition,page no:294. <\p>
Social & Preventive Medicine
{ "Correct Answer": "Specific Flea index", "Correct Option": "B", "Options": { "A": "General Flea index", "B": "Specific Flea index", "C": "Incidence of Fle species", "D": "Flea infestation Rate" }, "Question": "What is the average number of fleas of each species per rodent called -" }
null
6c68e78f-09e1-4dc6-8a22-b2469804b24e
Ans: B i.e. 10 days The earliest sign to appear on the X-ray is a periosteal new bone deposition (periosteal reaction) at the metaphysis. It takes about 7-10 days to appear Osteomyelitis Earliest site of involvement: Metaphysis Diagnosis of acute OM: Blood culture (positive in 65% cases) Periosteal reaction seen in acute OM appears after: 10 days MC organism in acute OM: Staph. aureus Brodies abscess: - Equilibrium between host & organism; - Abscess cavity remains without fuher enlargement
Surgery
{ "Correct Answer": "10 days", "Correct Option": "B", "Options": { "A": "5 days", "B": "10 days", "C": "15 days", "D": "20 days" }, "Question": "Periosteal reaction in a case of acute osteomyelitis can be seen earliest at: March 2012" }
null
65aaa955-47b2-4791-b9c2-e3272ba7b4e1
Ans. C: Pigmentation Acrodermatitis enteropathica is a rare inherited form of zinc deficiency, characterized by periorificial and acral dermatitis, alopecia, and diarrhea. Symptoms of Zinc Deficiency Poor Immune system Weight loss Intercurrent infections Hypogonadism in males Lack of sexual development in females Growth retardation Dwarfism Delayed pubey in adolescents Rough skin Poor appetite Mental lethargy Delayed wound healing Sho stature Diarrhea One easily recognized sign which may be caused by zinc deficiency is white spots, bands, or lines on fingernails (leukonychia). Some women may have multiple parallel white bands or lines on the fingernails marking menstrual cycles when marginal zinc deficiency was present.
Medicine
{ "Correct Answer": "Pigmentation", "Correct Option": "C", "Options": { "A": "Delayed wound healing", "B": "Loss of libido", "C": "Pigmentation", "D": "Sexual infantilism" }, "Question": "Which of the following is not associated with zinc deficiency: March 2005" }
null
abf516bd-aeec-4fee-a74e-4fcaf83bdeec
Pre implantation genetic diagnosis is used for daignosis of single gene disorders such as cystic fibrosis, β - thalassemia and hemophilia.
Gynaecology & Obstetrics
{ "Correct Answer": "Single gene mutation analysis", "Correct Option": "B", "Options": { "A": "Fetal gender determination", "B": "Single gene mutation analysis", "C": "HLA typing", "D": "Karyotyping" }, "Question": "Preimplantataion genetic diagnosis is used for" }
null
0a1b9d20-8102-4e64-a537-5cc6068abea5
Ans. is 'a' i.e., It follows zero order kinetics Phenytoin is metabolized in liver by hydroxylation and glucuranide conjugation (option 'c' is incorrect) o This drug follows saturation kinetics (kinetics changes from first order to zero order within therapeutic concentrations) Phenytoin is an enzyme inducer and induces the metabolism of many drugs. Phenytoin is a known teratogenic and produces fetal hydantoin syndrome.
Pharmacology
{ "Correct Answer": "It follows zero order kinetics", "Correct Option": "A", "Options": { "A": "It follows zero order kinetics", "B": "Not an hepatic enzyme inducer", "C": "It is excreted unchanged in urine", "D": "It is not teratogenic" }, "Question": "Which of the following about phenytoin is true ?" }
null
93e16540-7e0c-4dd7-aa21-caeb07a1d676
Stagardt's disease is autosomal recessive.
Ophthalmology
{ "Correct Answer": "Autosomal dominant", "Correct Option": "A", "Options": { "A": "Autosomal dominant", "B": "No family history", "C": "Beaten bronze appearance fundus", "D": "ERG and EOG both are normal" }, "Question": "False about stagardt's disease" }
null
c554afb1-9705-4a40-b97d-30e243390fc3
17-D vaccine is a live attenuated vaccine used to control yellow fever. Killed vaccines are used to control typhoid, cholera, peusis, plague, rabies, salk (polio), influenza, hepatitis A, B, japanese encephaltis and KFD. Ref: Park's Textbook Of Preventive and Social Medicine 20th edition page 98.
Social & Preventive Medicine
{ "Correct Answer": "17-D Vaccine", "Correct Option": "C", "Options": { "A": "Salk", "B": "Hepatitis B vaccine", "C": "17-D Vaccine", "D": "HDCV" }, "Question": "All of the following are killed vaccines, EXCEPT:" }
null
81697ce5-1551-43f9-a2c6-b41cf41fb01b
Ans. is 'd' i.e., Pleural surface Kerley's line Kerley's line is a linear opacity which, depending on its locaton, extent and orientation, may be be fuher classified as :? Kerley's A lines o These are thin, non-branching lines radiating from hilum. These lines are 2-6 cm in length. These lines are found in the mid and upper zones of the lung fields pleural. These lines are due to the thick interlobar septa. Kerley's B lines (septal lines) These are transverse (Horizontal) lines at the lung base pleural. These are 1-2 cm in length and are perpendicular to pleura. Kerley's B line is due to the thickening of interlobar septa due to edema caused by pulmonary venous hypeension (congestion), as occurs in left ventricular failure or mitral stenosis
Medicine
{ "Correct Answer": "Pleural surface", "Correct Option": "D", "Options": { "A": "Apex", "B": "Cardiophrenic angle", "C": "Lung fissure", "D": "Pleural surface" }, "Question": "Kerley B line are seen at" }
null
397b415a-2a93-42de-a74c-727db8f8ea83
Site of injection should be cleaned with soap but not with disinfectant or spirit.
Microbiology
{ "Correct Answer": "Site of injection should be cleaned with spirit", "Correct Option": "D", "Options": { "A": "WHO recommends Danish 1331 strain of M.bovis", "B": "Given intradermally", "C": "Normal saline is a diluent", "D": "Site of injection should be cleaned with spirit" }, "Question": "All of the following are true about BCG vaccine except." }
null
202f3a45-d0cd-490a-92f8-7dcf2bf230b3
A. i.e. Viral
Skin
{ "Correct Answer": "Viral", "Correct Option": "A", "Options": { "A": "Viral", "B": "Bacterial", "C": "Food", "D": "Drugs" }, "Question": "Commonest etiology of erythema multiforme is -" }
Community Ophthalmology
79e04d67-af42-4b0e-b242-cd83473eed50
Dr RP Centre for Ophthalmic Sciences, New Delhi has been designated as the apex national institute of ophthalmology.
Ophthalmology
{ "Correct Answer": "Dr. R P Centre for Ophthalmic Sciences , Delhi", "Correct Option": "C", "Options": { "A": "Advance eye care PGI Chandigarh", "B": "RIO", "C": "Dr. R P Centre for Ophthalmic Sciences , Delhi", "D": "Shankara Netralaya , Chennai" }, "Question": "Apex national institute of ophthalmology is" }
null
5b6dc8b7-df2e-4cee-8466-bdafd94dc6c6
Ans. Nd-YAG
Ophthalmology
{ "Correct Answer": "Nd-YAG", "Correct Option": "C", "Options": { "A": "Argon", "B": "Krypton", "C": "Nd-YAG", "D": "Excimer" }, "Question": "Which laser is used in the management of after cataracts:" }
Miscellaneous
ae109a16-29aa-4d8f-89e7-24dc53863115
Ans. A. The most common site is scalpKaposi sarcoma is mostly seen in extremities: most commonly on feet and occasionally on hands, ears, and nose.* Lesions are usually dark blue or purple and they may blanchewhen tumid (swollen).* Locally aggressive lesions can ulcerate, fungate or leave pigmented scars.* Lesions are usually multifocal which eventually fuse to form plaques and tumors of several centimeters in size.* Lymph nodes, mucosae and viscera may be involved as the disease progresses, although this can occur without skin involvement.Characteristic purple-colored plaques on the alar and tip of the nose in an HIV-positive female patient.
Skin
{ "Correct Answer": "The most common site is scalp", "Correct Option": "A", "Options": { "A": "The most common site is scalp", "B": "Lesions are dark blue or purple mostly", "C": "They are usually multifocal", "D": "Lymph nodes may be involved" }, "Question": "Which of the following statements about Kaposi sarcoma is not true?" }
null
b99f828c-44db-4bb5-b862-ead7b0034e98
Veins which do not have valves are:IVCSVCHepatic, ovarian, uterine, renal, emissary, cerebral, pulmonary, and umbilical veinsPoal venous system is a valveless system
Anatomy
{ "Correct Answer": "Femoral vein", "Correct Option": "A", "Options": { "A": "Femoral vein", "B": "Poal vein", "C": "IVC", "D": "Dural venous sinuses" }, "Question": "All of the following veins lack valves except" }
null
1da9268f-ba06-4576-8f19-ca634a3e0dce
null
Pathology
{ "Correct Answer": "Biopsy", "Correct Option": "C", "Options": { "A": "Bacterial smear", "B": "Blood studies", "C": "Biopsy", "D": "Blood chemistry" }, "Question": "The best laboratory test to use in the diagnosis of Lupus vulgaris in the oral cavity is:" }
null
7b7870d5-cd64-4e63-b9d5-cdf8aa81f9c5
Ans. B i.e. Black people Melanoma is commoner in fair complexion Malignant melanoma/ MM Mode of spread of MM: Lymphatic channels or hematogenous Cutaneous melanoma arises from: Epidermal melanocytes MC site involved in lentigo maligna (least common): Face MC type of MM: Superficial spreading Most malignant type of MM: Noduar melanoma
Surgery
{ "Correct Answer": "Black people", "Correct Option": "B", "Options": { "A": "Exposure to UV radiation", "B": "Black people", "C": "First degree relative with melanoma", "D": "Multiple or dysplastic naevi" }, "Question": "Risk factor for melanoma are all of the following EXCEPT: March 2013" }
Anti Microbial
c939bbeb-af27-43ec-8ad1-d7f70f5543eb
Ans. is 'a' i.e., Ofloxacin Drugs acting on M. leprae* Established agents used to treat leprosy include dapsone (50-100 mg/d), clofazimine (50-100 mg/d, 100 mg three times weekly, or 300 mg monthly), and rifampin (600 mg daily or monthly. Of these drugs, only rifampin is bactericidal.* The sulfones (folate antagonists), the foremost of which is dapsone, were the first antimicrobial agents found to be effective for the treatment of leprosy and are still the mainstay of therapy.* Other antimicrobial agents active against M. leprae in animal models and at the usual daily doses used in clinical trials include ethionamide/prothionamide; the aminoglycosides streptomycin, kanamycin, and amikacin (but not gentamicin or tobramycin); minocycline; clarithromycin; and several fluoroquinolones, particularly preferred is ofloxacin.* Next to rifampin, minocycline, clarithromycin, and ofloxacin appear to be most bactericidal for M. leprae, but these drugs have not been used extensively in leprosy control programs. Most recently, rifapentine and moxifloxacin have been found to be especially potent against M. leprae in mice. In a clinical trial in lepromatous leprosy, moxifloxacin was profoundly bactericidal, matched in potency only by rifampin.
Pharmacology
{ "Correct Answer": "Ofloxacin", "Correct Option": "A", "Options": { "A": "Ofloxacin", "B": "Pefloxacin", "C": "Ciprofloxacin", "D": "Moxifloxacin" }, "Question": "Preferred fluoroquinolone against m. leprae is -" }
Ear
7d6c6949-7c51-44f2-9c75-3be538acae26
DEGREES OF HEARING LOSS 0-25dB-Not significant impairment- no significant difficulty with faint speech 26-40dB-Mild impairment-Difficult with faint speech 41-55dB-Moderate impairment -Frequently difficult with normal speech 56-70dB-Moderately severe impairment-Frequently difficult with loud sound 71-91dB-Severe impairment-Can understand only shouted or amplified sound Above 91-Profound impairment-Usually cannot understand even amplified sound Ref: Diseases of EAR, NOSE AND THROAT by PL DHINGRA - 6th Edition. Page no. 39
ENT
{ "Correct Answer": "Severe hearing loss", "Correct Option": "C", "Options": { "A": "Mild hearing loss", "B": "Moderate hearing loss", "C": "Severe hearing loss", "D": "Profound hearing loss" }, "Question": "When the patient fails to understand normal speech but can understand shouted or amplified speech the hearing loss is termed as" }
null
aa99ff73-6f36-4c45-a44a-86a3bbf319fb
null
Pharmacology
{ "Correct Answer": "Block the influx of sodium into the cell", "Correct Option": "B", "Options": { "A": "Block the release of neurotransmitters", "B": "Block the influx of sodium into the cell", "C": "Increase the release of inhibitory neurotransmitters", "D": "Inhibit the efflux of sodium from neurons" }, "Question": "Local anaesthetics :" }
null
cac8d3b2-1ef7-459d-8ee5-7582fb4d7f0e
null
Dental
{ "Correct Answer": "Periodontal probe", "Correct Option": "C", "Options": { "A": "Periodontal hoe", "B": "Periodontal curette", "C": "Periodontal probe", "D": "Periodontal sickle" }, "Question": "Gingival sulcus is V shaped and it barely permits the entrance of a" }
null
70e492ea-3cbe-4dbb-a180-fc3bdd1df593
Ans. is 'b' i.e., Laryngotracheobronchitis This child has : - i) 3 days history of upper respiratory tract infection. ii) Followed by stridor These features suggest the diagnosis of croup. Clinical manifestations of Croup Most patients have an upper respiratory tract infection with some combination of - Rhinorrhea Pharyngitis Mild cough Low grade fever o After 1-3 days signs and symptoms of upper respiratory tract obstruction become apparent - Barking cough Hoarseness Inspiratory stridor
Pediatrics
{ "Correct Answer": "Laryngotracheobronchitis", "Correct Option": "B", "Options": { "A": "Acute Epiglottitis", "B": "Laryngotracheobronchitis", "C": "Foreign body aspiration", "D": "Retropharyngeal abscess" }, "Question": "A child with three days history of upper respiratory tract infection presents with stridor, which decreases on lying down postion. What is the most probable diagnosis -" }
null
ccfdaf28-aa1a-49c4-84b1-943e68d6b648
null
Dental
{ "Correct Answer": "Streptococci", "Correct Option": "A", "Options": { "A": "Streptococci", "B": "Bacteroides", "C": "Spirocheates", "D": "Actinomyces" }, "Question": "Predominant bacteria found in two days old plaque" }
null
d553ada9-cbb7-4fab-95f3-c4cc4ce536dd
Flexion injury is the commonest spinal injury. Ref: Essential ohopedics by Maheshwari 3rd Edition, Page 144,259,260.
Surgery
{ "Correct Answer": "Flexion", "Correct Option": "A", "Options": { "A": "Flexion", "B": "Extension", "C": "C Rotation", "D": "Compression" }, "Question": "Most common movemnet force involved in fractures of the spine is which of the following?" }
null
dadacc3d-d999-45e2-a343-f58debb1da3b
Pseudoridine arm of tRNA is involved in binding of aminoacyl tRNA to ribosomal surface.
Biochemistry
{ "Correct Answer": "Pseudouridine arm", "Correct Option": "B", "Options": { "A": "DHU arm", "B": "Pseudouridine arm", "C": "Acceptor arm", "D": "Anticodon arm" }, "Question": "Which arm of tRNA binds it to vibosomal surface" }
Contraception
e209480e-ce98-4f4e-9bd6-883ee8cc4bfa
Mirena now used as first line of treatment of menorrhagia, in addition to the contraceptive effect. Another use is in providing progestogens component of hormone replacement therapy after menopause. THE TEXTBOOK OF GYNAECOLOGY SHEILA BALAKRISHNAN SECOND EDITION PAGE NO 379
Gynaecology & Obstetrics
{ "Correct Answer": "stage 2 endometrial cancer", "Correct Option": "D", "Options": { "A": "Management of menorrhagia", "B": "Contraceptive effect", "C": "Hormone replacement therapy after menopause", "D": "stage 2 endometrial cancer" }, "Question": "Benefits of LNG lUCD are all except :" }
Miscellaneous
53c85cf9-4ec1-4485-91cf-1bd3b077dbaf
(A) Dystonia # Drug Induced & Tardive Movement Disorders> Movement disorders secondary to pharmacological agents represent a large number of extrapyramidal disorders seen by neurologists and psychiatrists in the outpatient setting.> Involuntary movements, including tremor, chorea, athetosis, dyskinesias, dystonia, myoclonus, tics, ballismus and akathisia, may be symptoms of primary neurologic disease or occur secondary to pharmacotherapy CHARACTERISTICS* TremorRhythmic. Oscillatory movement categorized according to its relationship to activity or posture* ChoreaIrregular, unpredictable brief jerky movements* AthetosisSlow, writhing movements of distal parts of limbs* DyskinesiasRecessive abnormal involuntary movements* DystoniaSlow sustained, posturing or contractions of a muscle or group of muscles* MyoclonusRapid, brief shock like muscle jerks* TicRepetitive, irregular stereotype movements or vocalizations* BallismusWild flinging or throwing movements* AkathisiaSubjective sensation of restlessness often associated with inability to keep still. Easily confused with psychiatric symptoms such as agitation, hyperactivity and anxiety> Central stimulants that act as indirect dopamine agonists such as amphetamine> Levodopa, a precursor of dopamine> Direct dopamine agonists such as bromocriptine> Presynaptic dopamine antagonists (dopamine depleting agents) such as reserpine> Neuroleptics such as haloperidol (Haldol) or chlorpromazine (Thorazine), and other medications such as metoclopramide (Reglan) which antagonize or block central dopamine receptors> By far, the most common cause of drug-induced and tardive syndromes are those that block or antagonize dopamine receptors, usually the neuroleptics.
Medicine
{ "Correct Answer": "Dystonia", "Correct Option": "A", "Options": { "A": "Dystonia", "B": "Chorea", "C": "Tardive dyskinesia", "D": "Hemiballismus" }, "Question": "Most common drug induced Extra Pyramidal Syndrome includes" }
null
a4294bee-22af-4c61-bdc0-be1a892d1e35
Early signs of elevated iCP include drowsiness and a diminished level of consciousness (altered mental status). Coma and unilateral papillary changes are late signs and require immediate intervention. Ref: Harrison's Internal Medicine, 16th Edition, Page 1633; Clinical Hepatology: Principles and Practice of Hepatobiliary Diseases By Henryk Dancygier, Scott L. (FRW) Friedman, H. D. (CON) Allescher, U. (CON) Beuers, Volume 2, 2010, Page 938
Surgery
{ "Correct Answer": "Altered mental status", "Correct Option": "C", "Options": { "A": "Ipsilateral pupillary dilatation", "B": "Contralateral pupillary dilatation", "C": "Altered mental status", "D": "Hemiparesis" }, "Question": "The earliest manifestation of increased intracranial pressure following head injury is:" }
Abdominal wall ,Inguinal and Femoral region
9068aea8-3633-4c43-b958-41861be80599
External oblique: Most superficial muscle which originates from the outer pa of the 5th to 12th ribs on each side of the rib cage. This muscle then runs diagonally down each side and connects to the iliac crest, linea alba, and the pubis. Function: External oblique contributes to the maintenance of abdominal tone, increasing intra-abdominal pressure (as in active expiration), and lateral flexion of the trunk against resistance. Bilateral contraction flexes the trunk forward and aid in movement of spine and back. Contraction of external oblique muscle approximates the two crura (medial and lateral) of superficial inguinal ring like a slit valve to maintain the integrity of inguinal canal.
Anatomy
{ "Correct Answer": "All of the above", "Correct Option": "D", "Options": { "A": "Anterior flexion of veebral column", "B": "Active expiration", "C": "Closure of inguinal ring", "D": "All of the above" }, "Question": "Function of external oblique muscle:" }
C.V.S
178a2e17-db01-44b3-9c8a-b5e62b5d1e8f
Absence of the P wave with a flat baseline may indicate: Fine atrial fibrillation Sinoatrial arrest (with a secondary escape rhythm ) in ventricular fibrilation ,ventriculat tachycardia and atrial asystole,a waves are present Ref Harrison 20th edition pg 1423
Medicine
{ "Correct Answer": "Atrial fibrillation", "Correct Option": "A", "Options": { "A": "Atrial fibrillation", "B": "Atrial asystole", "C": "Ventricular fibrillation", "D": "Ventricular tachycardia" }, "Question": "P wave is absent in-" }
null
757489e2-1d81-48b0-b83c-9015ebb54943
The addition of a poly A tail to the 3' end is one of the post-transcriptional modifications that occurs in the processing of eukaryotic messenger RNA (mRNA). A cap consisting of a guanosine derivative is attached to the 5' end. Intervening sequences (introns) are removed by splicing. All of these processing events occur in the nucleus of eukaryotes. Prokaryotic mRNA undergoes none of these modifications.
Surgery
{ "Correct Answer": "3' end of a eukaryotic mRNA", "Correct Option": "D", "Options": { "A": "5' end of a prokaryotic messenger RNA (mRNA)", "B": "3' end of a prokaryotic mRNA", "C": "5' end of a eukaryotic mRNA", "D": "3' end of a eukaryotic mRNA" }, "Question": "A Poly A base sequence would be most likely found at the" }
null
0297e7f0-4705-4b8d-9289-98ec58229859
Type I RPGN is anti - GBM mediated and it is seen in Goodpasture's syndrome.
Pathology
{ "Correct Answer": "Goodpasture's syndrome", "Correct Option": "C", "Options": { "A": "Cryoglobulinemia", "B": "SLE", "C": "Goodpasture's syndrome", "D": "Wegner's granulomatosis" }, "Question": "Type I RPGN is seen in" }
null
a8f0ecfa-295c-46ae-9357-5aa92429e19d
Ans: C (Succinyl choline) Ref: Ajay Yadav, Short textbook of Pediatrics, 1st editionExplanation:Cardiac Sideeffects of Anesthetic DrugsDrugsCardiac Side effectsMidazolamMinimal reduction in Heart rate, Blood pressure and cardiac outputEpinephrineProduces tachycardia, hypertension and ventricular arrhythmiasSuccinyiCholineIt produces muscarinic effects, similar to Acetyl cholineIt causes Profound BRADYCARDIA, so atropine should be given prior to use of Succinylcholine Choline, especially in childrenDopamineProduces tachycardia, hypertension and ventricular arrhythmiasThiopentoneit causes Hypotension, which is more because of venodilatation and direct depression of vasomotor centreDirect myocardial depressant
Unknown
{ "Correct Answer": "Succinyl choline", "Correct Option": "C", "Options": { "A": "Midazolam", "B": "Epinephrine", "C": "Succinyl choline", "D": "Dopamine" }, "Question": "Bradycardia is seen with:" }
null
3cd896db-2ff3-451c-9e7e-e6865e50453d
null
Psychiatry
{ "Correct Answer": "Othello syndrome", "Correct Option": "B", "Options": { "A": "Capgras syndrome", "B": "Othello syndrome", "C": "Hypochondrial paranomia", "D": "Declerambault's syndrome" }, "Question": "Infidelity & jealousy involving spouse is the thought content of which disorder -" }
Small & Large Intestine
eed4f2ca-a443-4de6-8bba-51cf3098269d
Ans: b (Congenital megacolon)Ref: Bailey & Love, 24th ed, p.l 153 & 23rd ed, p. 1027
Surgery
{ "Correct Answer": "Congenital megacolon", "Correct Option": "B", "Options": { "A": "Albinism", "B": "Congenital megacolon", "C": "Odontomes", "D": "Adrenal tumour" }, "Question": "Failure of migration of neural crest cells is seen in:" }
null
e07a117b-53b8-4029-8b7e-4d97bd1ef590
Ans. b. Weight loss
Surgery
{ "Correct Answer": "Weight loss", "Correct Option": "B", "Options": { "A": "Pain", "B": "Weight loss", "C": "Increase in size", "D": "Increase in thickness of cailage cap" }, "Question": "The signs of malignant transformation in osteochondroma are all except" }
null
80a59636-4395-44dd-b040-48c3ae1dfb49
null
Dental
{ "Correct Answer": "1.2 mm in width", "Correct Option": "D", "Options": { "A": "12 mm in length", "B": "1.2 mm in length", "C": "12 mm in width", "D": "1.2 mm in width" }, "Question": "The number 12 in a 3 unit formula 12-6-8 indicates the blade is" }
null
ff3bc438-722d-4724-8f52-5f7597ea4bd3
null
Social & Preventive Medicine
{ "Correct Answer": "ab", "Correct Option": "C", "Options": { "A": "ac", "B": "a", "C": "ab", "D": "bc" }, "Question": "Prophylaxis for health personnel working in a plague ward is -a) Vaccineb) Tetracycline throughout the dutyc) A cource of tetracyclined) Vaccine and Erythromycine) Observation" }
Blistering disorders
58a3c43f-c28a-4679-96ad-f95dafd52835
Drugs that most commonly cause SJS/TEN Antibiotics Antifungals Antivirals Sulfonamides, e.g., cotrimoxizole; beta-lactams i.e. penicillins, cephalosporins Imidazole antifungals Nevirapine (non-nucleoside reverse-transcriptase inhibitor) Allopurinol Nonsteroidal anti-inflammatory drugs (NSAID) (oxicam type mainly) Naproxen Ibuprofen Anti-convulsants Carbamazepine Phenytoin Phenobarbital Valproic acid Lamotrigine
Dental
{ "Correct Answer": "Paracetamol", "Correct Option": "D", "Options": { "A": "Cephalosporins", "B": "Ibuprofen", "C": "Carbamazepine", "D": "Paracetamol" }, "Question": "Drugs known to cause Steven Johnson syndrome include the following except:" }
Nervous system
70ccdb13-7ec5-4de9-aeaf-6ffb4d184372
Neurapraxia is a disorder of the peripheral nervous system in which there is a temporary loss of motor and sensory function due to blockage of nerve conduction, usually lasting an average of six to eight weeks before full recovery.Ref: Ganong&;s review of medical physiology 23rd edition
Physiology
{ "Correct Answer": "Neuropraxia", "Correct Option": "A", "Options": { "A": "Neuropraxia", "B": "Axonotemesis", "C": "Neurotemesis", "D": "Complete transaction" }, "Question": "Best prognosis in nerve injury" }
Organic Mental Disorder
b6be509b-8060-4678-80d8-605dccfc56a5
Ans. is 'a' i.e., MMSE o The most w idely used test for bedside evaluation of the mental status is folstein's mini mental state examination (MMSE).
Psychiatry
{ "Correct Answer": "MMSE", "Correct Option": "A", "Options": { "A": "MMSE", "B": "GCS", "C": "MMPI", "D": "WAIS" }, "Question": "Bedside test for mental status-" }
Urology
d73190cf-3f68-4d02-a7f5-0d6fac8cdcdb
pt. is suspected to have Ca Prostate as Prostatic Ca is the most common malignant tumor in men over 65 yrs. of age. Symptoms of Bladder outlet obstruction and back pains (due to bony metastasis in the pelvis & lumbar veebra) indicate towards prostate Ca. Serum acid phosphates is a tumor marker of prostate Ca. But now serum acid phosphates assay has been superseded by PSA assay (Prostate specific antigen). Prostate-specific antigen It is a glycoprotein produced only in the prostatic cells (both benign & malignant). It facilitates liquefaction of semen. It is neither sensitive nor specific for early prostate carcinoma (it is prostate specific and not prostate cancer specific), neveheless it gives some help in making a diagnosis. Normal serum level - less than 4 mg/ml 4 - 10 mg/ml - this range is common for both BHP and Ca. More than 10 mg/ml - approx 75% will have cancer. Since PSA is not specific for Ca, PSA Velocity & PSA density is used to detect Prostate cancer. PSA velocity is the rate of change in PSA levels over time and is expressed most commonly as the PSA doubling time. For men with a PSA above 4, PSA velocity of more than .75 mg/ml year is suggestive of Ca. While for those with lower PSA levels, rates above 0.5 mg/ml, per year should be used to advise biopsy. PSA density is calculated by dividing the serum PSA by the estimated prostate weight (measured by TRUS). It was developed to correct for the contribution of BPH to the total PSA level. Values < 0.10 are consistent with BPH. > 0.15 suggest cancer Ref : Bailey & Love 25/e p1356
Anatomy
{ "Correct Answer": "Serum acid phosphatase", "Correct Option": "A", "Options": { "A": "Serum acid phosphatase", "B": "Serum Calcium", "C": "Serum alkaline phosphatase", "D": "Serum electrophoresis" }, "Question": "A 70-year-old man comes to casualty with urinary retention and back pain. Which investigation should be performed -" }
null
a188906b-d986-4bad-9952-126f99fd2a30
null
Gynaecology & Obstetrics
{ "Correct Answer": "Pregnancy beyond 14 weeks", "Correct Option": "D", "Options": { "A": "Leaking membranes", "B": "Features of amnionitis", "C": "History of vaginal bleeding", "D": "Pregnancy beyond 14 weeks" }, "Question": "Contraindications of circlage operation are all except:" }
Chemotherapy
2a60f39a-e630-4fe9-9836-6a32f37d3809
Refer KDT 6/e p688 Resistance to fluoroquinolone is mediated by mutation in DNA gyrase
Pharmacology
{ "Correct Answer": "Quinolone", "Correct Option": "A", "Options": { "A": "Quinolone", "B": "Pencillin", "C": "Chloramphenicol", "D": "Aminoglycoside" }, "Question": "Elaboration of inactivating enzymes are the impoant mechanism of drug resistance among all of these antibiotics except" }
null
9f1744a7-19f6-4169-8465-c6a816133865
null
Medicine
{ "Correct Answer": "Dubin Johnson syndrome", "Correct Option": "D", "Options": { "A": "Hemolytic jaundice", "B": "Crigler Najjar syndrome", "C": "Gilbert's syndrome", "D": "Dubin Johnson syndrome" }, "Question": "A patient presents with unconjugated hyperbilirubinemia and presence of urobilinogen in urine. Which amongst the following is the least likely diagnosis -" }
null
a6c666a5-7859-43f7-8ddd-6422068d04e5
A confounding factor is defined as one which is associated both with exposure and disease, and is distributed unequally in study and control groups. More specifically a confounding factor is one that, although associated with exposure under investigation, is itself, independently of any such association, a risk factor for the disease. Ref: Park's Textbook of Preventive and Social Medicine, 19th edition, Page 67.
Social & Preventive Medicine
{ "Correct Answer": "It is itself a risk factor for the disease", "Correct Option": "B", "Options": { "A": "It is found equally between study and the control groups", "B": "It is itself a risk factor for the disease", "C": "Confounding can be eliminated by selecting a small group", "D": "It is associated with either the exposure or the disease" }, "Question": "Which among the following is TRUE about confounding factor?" }
All India exam
8293f730-fd62-4d63-bfd7-c758905013c1
Gastrografin (water soluble) is preferred to prevent extravasation of barium into the mediastinum or pleura. If no leak is seen, a barium study should follow
Surgery
{ "Correct Answer": "Water soluble low molecular weight contrast swallow", "Correct Option": "D", "Options": { "A": "Dynamic MRI", "B": "Rigid esophagoscopy", "C": "Barium contrast swallow", "D": "Water soluble low molecular weight contrast swallow" }, "Question": "Investigation of choice for esophageal rupture is" }
Autonomic nervous system
b59118d8-34fc-4814-935c-523da1791c48
Dopamine (DA):- It is a dopaminergic (D1 and D2) as well as adrenergic a and b1 (but not b2) agonist. Dobutamine:- A derivative of DA, but not a D1 or D2 receptor agonist. Though it acts on both a and b adrenergic receptors. Ref:- kd tripathi; pg num:-134
Pharmacology
{ "Correct Answer": "It does not activate peripheral dopaminergic receptors", "Correct Option": "D", "Options": { "A": "It has good blood-brain barrier penetrability", "B": "It causes pronounced tachycardia", "C": "It does not activate adrenergic b receptors", "D": "It does not activate peripheral dopaminergic receptors" }, "Question": "Dobutamine differs from dopamine in that" }
Poisoning
0ee1e184-ebb7-4f8d-8029-fc644944ce06
Postmoem appearance Esophagus and stomach shows inflammatory changes and luminous material may be seen in the GIT. There may be garlicky odour in the gastric contents. There may be jaundice, and fatty change in the liver. Liver shows centrilobular steatosis and neurosis. If the person survived for one week or so, there may be yellow atrophy of liver and cloudy swellings of kidney. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 432
Anatomy
{ "Correct Answer": "Phosphorus", "Correct Option": "B", "Options": { "A": "Sulphur", "B": "Phosphorus", "C": "Iodine", "D": "Chlorine" }, "Question": "Garlicky odour in the gastric contents seen in which non metallic poisoning" }
null
5f4b321f-8d37-411c-b1ab-7262eb4a2a2e
null
Medicine
{ "Correct Answer": "Cystic fibrosis", "Correct Option": "C", "Options": { "A": "Ehlers Danlos syndrome", "B": "Marfan syndrome", "C": "Cystic fibrosis", "D": "Diabetes insipidus" }, "Question": "Abnormal function of epithelial chloride channel protein is the cause of" }
null
4aba0ab7-8db0-4de7-99be-fdf787ed3f0c
Cryptococcus is the capsulated yeast. Among the given staining techniques, India ink preparation is the best staining technique used for demonstration of capsule (negative staining) - sensitivity of the technique: 60–75%. Other capsular staining techniques are: 10% Nigrosin staining Modified India ink preparation with 2% chromium mercury Alcian blue staining Methanamine silver and Periodic acid- Schiff – used for tissue sample. Sensitivity of various diagnostic tests- Harrison 18/e p1652 Cryptococcal antigen detection in CSF—90% Blood culture: 10—30% in non-HIV patients and 60% in HIV patients Sputum culture: 10% Sputum antigen detection: 30%
Microbiology
{ "Correct Answer": "India ink preparation", "Correct Option": "B", "Options": { "A": "Gram stain", "B": "India ink preparation", "C": "Giemsa stain", "D": "Methenamine-silver stain" }, "Question": "The capsule of cryptococcus neoformans in a CSF sample is best seen by -" }
All India exam
aa2c69c6-22ee-43c0-8c4b-6c73a2ff84b0
ref : harrisons 21st ed
Radiology
{ "Correct Answer": "Oligemia", "Correct Option": "D", "Options": { "A": "Kerley B lines", "B": "Kerley A lines", "C": "Cardiomegaly", "D": "Oligemia" }, "Question": "which is not a radiographic finding of CHF" }
null
0a8d5e9a-0c63-4550-adde-ea69ba439d37
Ans. is 'd' i.e., Bi-fascicular block Bifascicular block - combination of RBBB with either left anterior hemiblock or left posterior hemiblock. Tri fascicular block - RBBB plus either LAHB/LPHB+ first degree AV block. Complete hea block destruction of - AV node leading to AV dissociation
Medicine
{ "Correct Answer": "Bi-fascicular block", "Correct Option": "D", "Options": { "A": "1' degree hea block", "B": "Complete hea block", "C": "Mobitz type II block", "D": "Bi-fascicular block" }, "Question": "Alternating RBBB with Left anterior hemiblock is seen in" }
null
69fa1e5c-3053-49cb-b4f0-2de8d464d5ef
Diagnosis is made by MRCP
Surgery
{ "Correct Answer": "Staging is done by PET CT", "Correct Option": "B", "Options": { "A": "Investigation of choices MRCP", "B": "Staging is done by PET CT", "C": "Diagnosis is done by CECT", "D": "Choledochal cyst is a risk factor." }, "Question": "Which of the following is false about cholangiocarcinoma" }
null
bdcc584c-b77b-461b-84f5-21a04ab33437
null
Medicine
{ "Correct Answer": "Ejection click", "Correct Option": "C", "Options": { "A": "Opening snap", "B": "Pericardial knock", "C": "Ejection click", "D": "Tumor plop" }, "Question": "All of the following heart sounds occur shortly after S2 except" }