topic_name
stringlengths
3
135
id
stringlengths
36
36
explanation
stringlengths
1
22.5k
subject_name
stringclasses
21 values
data
dict
null
f0f4b676-ab5a-4469-916c-bdfd4113be62
Side effects of clozapine Agranulocytosis Urinary incontinence Unstable BP & Tachycardia Hypersalivation (sialorrhoea) Worsening of diabetes Weight gain Seizures Sedation
Psychiatry
{ "Correct Answer": "Sialorrhea", "Correct Option": "B", "Options": { "A": "Hypertension", "B": "Sialorrhea", "C": "Extrapyramidal S/E", "D": "Neuroleptic malignant syndrome" }, "Question": "The adverse effect of clozapine -" }
null
54941263-b5cb-47b5-9078-427f5c9d1817
ANSWER: (B) SepsisREF: Forensic Medicine and Toxicology By R.N.Karmakar page 230, Textbook of Forensic Medicine and Toxicology, Krishan Vij 5th ed fig 26.2The most common complication from illegal abortion is retained product of conception; the most frequent cause of death is infection and sepsis.NATURAL VS CRIMINAL ABORTION Natural abortionCriminal abortionCauseSpontaneousInducedPrecipitating factorMaternal or fetal diseaseUnwanted pregnancyEvidence of genital violenceAbsentPresentForeign body from genitalsAbsentMay be presentToxic effect of drugAbsentMay be presentFetal injuryAbsentRarely present
Unknown
{ "Correct Answer": "Sepsis", "Correct Option": "B", "Options": { "A": "Hemorrhage", "B": "Sepsis", "C": "Air embolism", "D": "Perforation" }, "Question": "Most common cause of death in criminal abortion is?" }
null
5ba3d7de-9e3f-42cf-9ba8-7330fd1c1701
Ans. is 'c' i.e., Rosuvastatin o Two most potent statins are Pitavastatin (most potent) and rosuvastatin most potent).
Pharmacology
{ "Correct Answer": "Rosuvastatin", "Correct Option": "C", "Options": { "A": "Simvastatin", "B": "Pravastatin", "C": "Rosuvastatin", "D": "Simvastatin" }, "Question": "Most potent statin -" }
null
786b732a-ad84-4eed-a356-cf042326920e
Copper T
Gynaecology & Obstetrics
{ "Correct Answer": "Copper T", "Correct Option": "B", "Options": { "A": "Barrier", "B": "Copper T", "C": "Oral pills", "D": "Spermicide" }, "Question": "Contraception of choice for a post paum village woman with one child :" }
null
4a8925ce-13f8-4d7c-b753-873cc4765df8
null
Pharmacology
{ "Correct Answer": "Amphotericin B", "Correct Option": "C", "Options": { "A": "Ketoconazole", "B": "Fluconazole", "C": "Amphotericin B", "D": "None of these" }, "Question": "All of the following antifungal drugs inhibit ergosterol biosynthesis EXCEPT :" }
Oncology
f8d1aab7-88d9-4a6a-982d-8f8ad20ddd8a
(b) Source: (Devita, pp. 533-534) Only the chronic carrier state increases HCC risk, not previous infection. The majority, but not all, of HCC associated with HBV occurs in the setting of cirrhosis (60-90%). Because the latency period of HBV infection is 35 years, before HCC supervenes, early-life infection is strongly correlated with HCC. The chronic carrier state of HBsAg in endemic areas, such as Taiwan, is associated with a relative risk of over 100 for the development of HCC. Over half the chronic carriers of HBsAg in such a population will die of cirrhosis or HCC. In Taiwan, where childhood vaccination was introduced in 1984, the death rate from childhood HCC has already declined.
Medicine
{ "Correct Answer": "hepatocellular carcinoma (HCC)", "Correct Option": "B", "Options": { "A": "hepatoma", "B": "hepatocellular carcinoma (HCC)", "C": "metastatic cancer", "D": "hepatic hemangioma" }, "Question": "A 33-year-old male immigrant from Taiwan presents with increasing right upper quadrant (RUQ) pain. The pain is dull, and it does not radiate or change with eating. On examination the abdomen is soft, there is a mass in the RUQ, and no ascites is clinically detected. He has a prior history of hepatitis B. His laboratory investigations reveal hepatitis B surface antigen (HBsAg) positive, hepatitis B surface antibody (HBsAb) negative, aspartate amino transferase (AST) 60 U/L, alanine amino transferase (ALT) 72 U/L, and an elevated alpha-fetoprotein level. Which of the following is the most likely diagnosis?" }
Blood Bank & Transfusion Therapy
76f0ee5a-e1a2-4021-b892-34dda1735a99
Done Before ABG Allen test: integrity of palmer arch. Heparin: to rinse the syringe Poking the aery at 45-degree angle. Extend wrist joint: Radial Aery tent.
Medicine
{ "Correct Answer": "Flexion of wrist", "Correct Option": "C", "Options": { "A": "Allen test", "B": "Heparin to rinse the syring", "C": "Flexion of wrist", "D": "Poking the aery at 45 degrees angle" }, "Question": "Which of the following is not done before ABG?" }
G.I.T
ab67dd74-7d14-41f7-9591-9b8e7a4c4151
MRI in Liver lesions MRI had emerged as the best imaging test for liver lesion detection and characterization MRI provides high lesion-to-liver contrast and does not use radiation Liver-specific contrast media, such as mangofodipir trisodium (taken up by hepatocytes) and ferrumoxides (taken up by kupffer cells) demonstrate selective uptake in the liver and primarily used for lesion detection These two contrast agents are also useful in characterising specific liver tumors, such as FNH, hepatic adenoma and HCC Ref: Shackelford 7th edition Pgno : 1560
Surgery
{ "Correct Answer": "MRI", "Correct Option": "A", "Options": { "A": "MRI", "B": "CT", "C": "USG", "D": "PET" }, "Question": "Focal lesion in liver is best detected by" }
null
507d5e62-2027-48e6-a7ba-07c8f343da89
null
Dental
{ "Correct Answer": "9-20% copper", "Correct Option": "A", "Options": { "A": "9-20% copper", "B": "13-20% copper", "C": "9-30% copper", "D": "13-30% copper" }, "Question": "Admixed high copper alloy powder contains" }
Diagnosis of Pregnancy
8156512f-8a11-47f3-8c3f-edfb0de612aa
CRL is the best USG parameter to determine gestational age in first trimester Crown rump length - it is the longest straight line measurement of the embryo from the other margin of cephalic pole to rump mid-sagittal plane with fetus in neutral , non fixed position - Best seen on TVS - Overall best USG parameter to assess the fetal age - Ideal time to measures CRL is 7 - 10 weeks - can be done upto 14 weeks
Gynaecology & Obstetrics
{ "Correct Answer": "Crown-rump length on abdominal or vaginal ultrasound", "Correct Option": "C", "Options": { "A": "Determination of uterine size on pelvic examination", "B": "Quantitative serum HCG level", "C": "Crown-rump length on abdominal or vaginal ultrasound", "D": "Determination of progesterone level along with serum HCG level" }, "Question": "A patient presents with LMP 8 weeks ago. She has history of delayed cycles in the past. Which of the following is the most accurate way of dating the pregnancy?" }
null
2f186270-7452-4e77-889d-c0a9bc89b0cc
All of the above
Anatomy
{ "Correct Answer": "All of the above", "Correct Option": "D", "Options": { "A": "It marks a divide in nerve supply", "B": "It marks the location of change in type of epithelium", "C": "It represents a lymphatic and venous divide", "D": "All of the above" }, "Question": "Pectinate line is an impoant landmark because?" }
Miscellaneous
c337bf74-49d1-4b5d-9838-04319f80bd54
(A) OCD # Obsessive-compulsive disorder (OCD) is a psychiatric anxiety disorder most commonly characterized by a subject's obsessive, distressing, intrusive thoughts and related compulsions (tasks or "rituals") which attempt to neutralize the obsessions.# Obsessions are defined by:> Recurrent and persistent thoughts, impulses, or images that are experienced at some time during the disturbance, as intrusive and inappropriate and that cause marked anxiety or distress.> Thoughts, impulses, or images are not simply excessive worries about real-life problems.> Person attempts to ignore or suppress such thoughts, impulses, or images, or to neutralize them with some other thought or action.> Person recognizes that the obsessional thoughts, impulses, or images are a product of his or her own mind, and are not based in reality.> Tendency to haggle over small details that the viewer is unable to fix or change in any way. This begins a mental pre-occupation with that which is inevitable.# Compulsions are defined by:> Repetitive behaviors or mental acts that the person feels driven to perform in response to an obsession, or according to rules that must be applied rigidly.> The behaviors or mental acts are aimed at preventing or reducing distress or preventing some dreaded event or situation; however, these behaviors or mental acts either are not connected in a realistic way with what they are designed to neutralize or prevent or are clearly excessive.
Psychiatry
{ "Correct Answer": "OCD", "Correct Option": "A", "Options": { "A": "OCD", "B": "Mania", "C": "Depression", "D": "Anxiety" }, "Question": "A lady used to repeatedly wash her hands due to the fear of acquiring AIDS is due to" }
Infectious Disease
df8d695f-de6a-4843-aeed-e80a6ea24c76
Cystic fibrosis is the most common lethal autosomal recessive disorder in the white population. The disease is characterized by (1) chronic pulmonary disease, (2) deficient exocrine pancreatic function, and (3) other complications of inspissated mucus in a number of organs, including the small intestine, the liver, and the reproductive tract. It results from abnormal electrolyte transport caused by impaired function of the chloride channel of epithelial cells. The pulmonary symptoms of CF begin with cough, which eventually becomes productive of large amounts of tenacious and purulent sputum. Episodes of infectious bronchitis and bronchopneumonia become progressively more frequent, and eventually shortness of breath develops. Respiratory failure and the cardiac complications of pulmonary hypertension (cor pulmonale) are late sequelae. The most common organisms that infect the respiratory tract in CF are Staphylococcus and Pseudomonas species. As the disease advances, Pseudomonas may be the only organism cultured from the lung. In fact, the recovery of Pseudomonas sp., particularly the mucoid variety, from the lungs of a child with chronic pulmonary disease is virtually diagnostic of CF.Diagnosis: Cystic fibrosis
Pathology
{ "Correct Answer": "Pseudomonas sp.", "Correct Option": "D", "Options": { "A": "Klebsiella sp.", "B": "Legionnella sp.", "C": "Pneumocystis sp.", "D": "Pseudomonas sp." }, "Question": "A 5-year-old boy is brought to the emergency room with a fever of 103degF (38.7degC), chest pain, and productive cough. The patient has a history of recurrent pulmonary disease and respiratory distress. What microorganism recovered from the lungs of this child is virtually diagnostic of cystic fibrosis?" }
Heart, Circulation, and Blood
5c30c58e-aa88-4ad7-9c3f-59e0fbae78c0
Ans. is 'a' i.e., 0.05 meter/sec Cardiac tissueConduction velocity (meter/second)SA node0 [?] 05Inteatrial pathways1Atrial muscle0 [?] 30AV node0 [?] 05 (minimum)Bundle of His1Purkinje system4 (maximum)Ventricular muscle1
Physiology
{ "Correct Answer": "0.05 meter/sec", "Correct Option": "A", "Options": { "A": "0.05 meter/sec", "B": "0.5 meter/sec", "C": "1 meter/sec", "D": "5 meter/sec" }, "Question": "Conduction velocity in AV node 8c SA node-" }
null
67addd49-aef4-4a17-8a92-cb1d6d4c5048
. Cells which are not able to express MHC 1
Pathology
{ "Correct Answer": "Cells which are not able to express MHC 1", "Correct Option": "B", "Options": { "A": "Cells which express MHC 1", "B": "Cells which are not able to express MHC 1", "C": "MHC cells which express MHC 2", "D": "Cells which are not able to express MHC" }, "Question": "Which of the following cells do Natural killer cells attack?" }
Epidemiology
382bb95e-7844-47d5-8371-4cfd97a22c7d
Surveillance has been defined as the continuous scrutiny of all aspects of occurrence and the spread of diseases that are peinent to effective control. Surveillance goes beyond the passive repoing of cases Ref: 25th edition, Park's Textbook of Preventive and Social Medicine, Page no. 138
Social & Preventive Medicine
{ "Correct Answer": "Surveillance", "Correct Option": "C", "Options": { "A": "Epidemiology", "B": "Monitoring", "C": "Surveillance", "D": "Screening" }, "Question": "Continues scrutiny of factors that affect the occurence of a disease is -" }
G.I.T
d5e663c9-e7c1-4d04-866a-8fd26dea53b1
MALLORY WEISS syndrome is seen in adults with severe prolonged vomiting, causing a longitudinal tear in the mucosa of the stomach at and just below the cardia leading to severe hematemesis.violent vomiting may be due to a migraine or veigo or following a bout of alcohol.common in 1 o' clock position.investigations include Hb%, PCV.treatment includes blood transfusion, IV fluids, sedation and hemostatic agents such as vasopressin. Ref: SRB&;s manual of surgery,3 rd ed, pg no 734
Surgery
{ "Correct Answer": "Cardia stomach", "Correct Option": "D", "Options": { "A": "Upper esophagus", "B": "Mid operation", "C": "Lower esophagus", "D": "Cardia stomach" }, "Question": "Most common site of tear in Mallory-weiss syndrome is in" }
Miscellaneous
ba2134ba-abee-4784-b236-ce9d70776cf7
(A) Granuloma > Granuloma usually presents with increased ICP, with massive parietal edema. CT/MRI shows single circumscribed region lesion. Gliomas include astrocytomas, oligodendrogliomas and mixed tumours. Common sites include the cerebellum, optic nerve and chiasma, hypothalamus and brainstem. Diffuse astrocytomas (WHO grade II) are most common in the fourth decade of life and often present with seizures or are incidental findings. CT scan shows enhancement which is often irregular around a centre of low density which may represent necrosis calcification may be present. Cerebral metastases are by far the most common intracranial tumours and will affect approximately one in every four cancer sufferers. They tend to occur in the fifth to seventh decades. The majority of patients with cerebral metastases have multiple lesions. Metastatic tumours show isodense on unenhanced CT and enhance vividly on intravenous contrast.
Surgery
{ "Correct Answer": "Granuloma", "Correct Option": "A", "Options": { "A": "Granuloma", "B": "Metastases", "C": "Glioblastoma", "D": "All of the above" }, "Question": "A patient presented with 2 months history of increased ICP, with massive parietal edema, CT/MRI shows single and were circumscribed region lesion" }
null
5a4be86e-b212-46aa-91ba-101c6bf23dd7
Ans. is 'c' i.e., Category 6
Social & Preventive Medicine
{ "Correct Answer": "Category 6", "Correct Option": "C", "Options": { "A": "Category 7", "B": "Category 9", "C": "Category 6", "D": "Category 5" }, "Question": "Incineration is done for waste category ?" }
null
daeb3aaf-6056-484e-a38a-5ef8af889e9a
Answer is C (Microangiopathic changes in blood vessels): Macroangiopathic changes in blood vessels in the form of peripheral aerial disease contribute to the generation of foot ulcers and non microangiopathic changes. Pathogenic Factors in generation of foot ulcers in DM Neuropathy (Peripheral Sensory neuropathy): Trophic changes Abnormal Foot Biomechanics (d/t disordered propioception and sensorimotor neuropathy) Peripheral Aerial disease (Macroangiopathy) and poor wound healing Autonomic neuropathv (anhidrosis and altered superficial blood flow in ,foot)
Medicine
{ "Correct Answer": "Microangiopathic changes in blood vessels", "Correct Option": "C", "Options": { "A": "Trophic ulcers", "B": "Neuropathy", "C": "Microangiopathic changes in blood vessels", "D": "Macroangiopathy" }, "Question": "Pathognomic factors involved in foot ulcers in DM include all, Except:" }
Cellular Pathology
9a6a5483-3749-4f06-bdb0-8d3aadf2990a
Ans. is 'b' i.e. Kupffer's cell hyperplasia with macrophage infiltration around periportal area laden with pigments * In severe infections with plasmodium falciparum, the vital organs are packed with erythrocytes containing mature form of the parasite.* There is abundant intra and extraerythrocytic pigment and organs such as liver, spleen and placenta may be grey black in colour.Also know * Durck's granuloma are pathognomic of malignant cerebral malaria.Histopathological features in liver due to falciparum malariaReticuloendothelial cell proliferation i.e., Kupffer cell hyperplasia.Malarial pigmentation i.e., haemoglobin pigmentation.CongestionPortal infiltration of the macrophageSinusoidal infiltration and sinusoidal dilatationCholestasisNuclear vacuolationLiver cell necrosisFatty changeBallooning of hepatocytesVacuolated cytoplasm's
Pathology
{ "Correct Answer": "Kupffer's cell hyperplasia with macrophage infiltration around periportal area laden with pigments.", "Correct Option": "B", "Options": { "A": "Microabscess formation", "B": "Kupffer's cell hyperplasia with macrophage infiltration around periportal area laden with pigments.", "C": "Non caseating granuloma", "D": "Non specific finding of neutrophilic infiltratio" }, "Question": "Finding on histopathological examination in liver in case of malaria is :" }
null
ebedbb4a-c05e-4942-907c-d7a3f943b37f
HbA/S heterozygotes (sickle cell trait) have a sixfold reduction in the risk of dying from severe falciparum malaria. This decrease in risk appears to be related to impaired parasite growth at low oxygen tensions and reduced parasitized red cell cytoadherence. Parasite multiplication in HbA/E heterozygotes is reduced at high parasite densities. Ref: White N.J., Breman J.G., Osler W. (2012). Chapter 210. Malaria. In D.L. Longo, A.S. Fauci, D.L. Kasper, S.L. Hauser, J.L. Jameson, J. Loscalzo (Eds), Harrison's Principles of Internal Medicine, 18e.
Pathology
{ "Correct Answer": "Protective against adult malaria", "Correct Option": "D", "Options": { "A": "Stability", "B": "Altered function", "C": "Decreased oxygen carrying capacity", "D": "Protective against adult malaria" }, "Question": "Which of the following is true about sickle cell red blood cells?" }
null
1737b275-7ba0-4c38-9de2-a4bdd3822a67
Ans. is 'a' i.e., Cotrimoxazole
Pharmacology
{ "Correct Answer": "Cotrimoxazole", "Correct Option": "A", "Options": { "A": "Cotrimoxazole", "B": "Erythromycin", "C": "Penicillin", "D": "Metronidazole" }, "Question": "Drug of choice for pneumocystis carinii ?" }
null
9002d192-e641-4d19-8c77-f898455cf855
This man has a respiratory acidosis. Overdose with drugs that suppress ventilation (e.g., heroin, morphine, barbiturates, methaqualone, and "sleeping pills") often causes hypercapnia. In patients with an intact renal response, the respiratory acidosis causes a compensatory rise in plasma HCO3-, which lessens the fall in pH. However, the renal response requires several days to develop fully. The plasma HCO3- of 26 mEq/L (normal: 22-28 mEq/L) for this man is typical of acute respiratory acidosis with little or no renal compensation. pH 7.34, PaCO2 (mm Hg) 29, HCO3- (mEq/L) 15 reflects metabolic acidosis. pH 7.40, PaCO2 (mm Hg) 40, HCO3- (mEq/L) 24 is normal. pH 7.47, PaCO2 (mm Hg) 20, HCO3- (mEq/L) 14 reflects respiratory alkalosis.
Medicine
{ "Correct Answer": "pH 7.22, PaCO2 (mm Hg) 66, HCO3- (mEq/L) 26", "Correct Option": "A", "Options": { "A": "pH 7.22, PaCO2 (mm Hg) 66, HCO3- (mEq/L) 26", "B": "pH 7.34, PaCO2 (mm Hg) 29, HCO3- (mEq/L) 15", "C": "pH 7.40, PaCO2 (mm Hg) 40, HCO3- (mEq/L) 24", "D": "pH 7.47, PaCO2 (mm Hg) 20, HCO3- (mEq/L) 14" }, "Question": "A 26-year-old man is admitted through the casualty of the hospital for a heroin overdose. His hea rate is 45 beats/min, and his blood pressure is 75/40 mm Hg. Which of the following best depicts the results from an aerial blood sample?" }
Injuries Around Shoulder
62654a1a-2b78-4b92-b306-35c20dfb1b73
Ans: b (Clavicle)Ref: Maheshwari Ortho, 3rd ed, p. 73
Orthopaedics
{ "Correct Answer": "Clavicle", "Correct Option": "B", "Options": { "A": "Radius", "B": "Clavicle", "C": "Femur", "D": "Vertebra" }, "Question": "Most common bone fracture in body is:" }
Larynx
78287b9c-d2ff-40bd-aa9f-afa70e8d805d
Mitomycin-C is an antineoplastic antibiotic that acts as an alkylating agent by inhibiting DNA and protein synthesis. ... Topical application of mitomycin-C (0.4 mg/mL) was used as an adjuvant treatment in the endoscopic laser management of laryngeal and tracheal stenosis Ref: Internet sources
ENT
{ "Correct Answer": "Mitomycin C", "Correct Option": "B", "Options": { "A": "Adriamycin", "B": "Mitomycin C", "C": "Cyclophosphamide", "D": "Doxorubicin" }, "Question": "Drug treatment for laryngeal stenosis is" }
C.V.S
dfe3c09d-5b5e-41a9-be50-cb272175c9e6
Graduated compression stockings (GCS) help prevent the formation of blood clots in the legs by applying varying amounts of pressure to different pas of the leg. Thigh or waist-high stockings help reduce pooling of blood in the legs and help prevent lightheadedness or falling when you stand up (ohostatic hypotension). Stockings that rise to just below the knee help limit lower leg swelling due to fluid buildup Ref Davidson 23rd edition pg 450
Medicine
{ "Correct Answer": "Graded compression stockings", "Correct Option": "A", "Options": { "A": "Graded compression stockings", "B": "Salbutamol", "C": "Fludrocoisone", "D": "b-blockers" }, "Question": "A 40 year old presenting with dizziness on standing with systolic reduction of BP of 50mm Hg; appropriate treatment" }
null
74f8db4f-702b-45d5-a690-e3f2cac78a5f
null
Dental
{ "Correct Answer": "<3 DMFT at 12 years", "Correct Option": "B", "Options": { "A": "<2 DMFT at 12 years", "B": "<3 DMFT at 12 years", "C": "<4 DMFT at 12 years", "D": "<5 DMFT at 12 years" }, "Question": "WHO global programme for oral health targets for 2000 irtclude;" }
null
6756d58a-7931-4c20-a4eb-e0d91428056c
Ans. is `c' i.e., Classify as severe pneumonia, sta antibiotics and refer urgently
Social & Preventive Medicine
{ "Correct Answer": "Classify as severe pneumonia, sta antibiotics and refer urgently", "Correct Option": "C", "Options": { "A": "Classify as pneumonia and refer urgently to secondary level hospital", "B": "Classify as pneumonia, sta antibiotics and advise to repo after 2 days", "C": "Classify as severe pneumonia, sta antibiotics and refer urgently", "D": "Classify as severe pneumonia and refer urgently" }, "Question": "A child aged 24 months was brought to the Primary Health Centre with complaints of cough and fever for the past 2 days. On examination, the child weighed 11kg, respiratory rate was 38 per minute, chest indrawing was present. The most appropriate line of management for this patient is ?" }
All India exam
a4ca461a-ede2-4d85-906a-419003eccfd9
USG shows highly reflective echogenic focus within the gallbladder lumen, with prominent posterior acoustic shadowing, characteristic of Cholelithiasis. If there is associated cholecystitis, gallbladder wall thickening along with the pericholecytic fluid. Murphy&;s sign might be elicited with probe over gallbladder.
Surgery
{ "Correct Answer": "Gall stone", "Correct Option": "A", "Options": { "A": "Gall stone", "B": "Cholecystitis", "C": "Porcelain gall bladder", "D": "Cholangiocarcinoma" }, "Question": "A 40-year-old female have a right hypochondriac pain. USG is taken. What is the inference?" }
null
fe71c76c-f651-44dd-9cce-ab9d8782fba3
null
Dental
{ "Correct Answer": "Gingival fibres and junctional epithelium", "Correct Option": "B", "Options": { "A": "Gingival fibres", "B": "Gingival fibres and junctional epithelium", "C": "P.D. fibres and ligament", "D": "None of the above" }, "Question": "Dentogingival unit comprises of" }
null
00c45685-53fb-40a9-a05a-1c75446522cd
Answer is C (Smoking):Smoking has not been mentioned as a risk factor, for Alzheimer's disease.
Psychiatry
{ "Correct Answer": "Smoking", "Correct Option": "C", "Options": { "A": "Down-syndrome", "B": "Low education level", "C": "Smoking", "D": "Female sex" }, "Question": "All of the following are known predisposing factors for Alzheimer's disease except :" }
General Pharmacology
8f726ce9-e9cf-40ea-a158-ff085d122e28
Ans. (C) Breakdown of GTP to GDP(Ref: KDT 8th/e p54)Alpha subunit of G protein contains GTPase activity and thus dissociates GTP to form GDP. This result in re-uniting a subunit with b and g subunit
Pharmacology
{ "Correct Answer": "Breakdown of GTP to GDP", "Correct Option": "C", "Options": { "A": "Binding of agonist", "B": "Conversion of GDP to GTP", "C": "Breakdown of GTP to GDP", "D": "Internalization of receptors" }, "Question": "Action of alpha subunit of G-protein is:" }
Gallbladder
6825a23d-8f16-4e4c-8c06-7130affb99e0
In the given question there was an episode of jaundice, but LFT is normal and CBD is not dilated. The best option is laparoscopic cholecystectomy only Management of CBD stones associated with GB stones * Pre-operatively detected stones:- * Unsuspected stones found at the time of cholecystectomy:- Experienced laparoscopic surgeon Experienced laparoscopic surgeon Cholecystectomy and choledochotomy in same sitting Laparoscopic CBD exploration and stone retrieval through the cystic duct * Laparoscopic choledochotomy and stone extraction Inexperienced laparoscopic surgeon Inexperienced laparoscopic surgeon Pre-op ERCP with stone removal and laparoscopic cholecystectomy later Conve to open procedure and remove CBD stone Complete the cholecystectomy and refer the patient for ERCP
Surgery
{ "Correct Answer": "Laparoscopic cholecystectomy", "Correct Option": "A", "Options": { "A": "Laparoscopic cholecystectomy", "B": "Open choledocholithotomy followed by laparoscopic cholecystectomy", "C": "ERCP + choledocholithotomy followed by Laparoscopic cholecystectomy", "D": "Laparoscopic cholecystectomy followed by ERCP + choledocholithotomy" }, "Question": "A 50 year old with history of jaundice in the past has presented with right upper quadrant abdominal pain. Examination and investigations reveal chronic calculous cholecystitis. The liver functions tests are within normal limits and on ultrasound examination, the common bile ducts is not dilated. Which of the following will be the procedure of choice?" }
null
380388e0-cdda-4430-954e-df5537a40c30
LONG THORACIC NERVE ■ Arises from ventral rami of C5, C6, and C7. ■ Descends behind the brachial plexus on the lateral surface of the serratus anterior, to which it supplies. ■ The serratus anterior muscle can be examined by asking patient to push against a wall with both hands. Winging of scapula will be typically noted
Anatomy
{ "Correct Answer": "Serratus anterior", "Correct Option": "A", "Options": { "A": "Serratus anterior", "B": "Supraspinatus", "C": "Teres minor", "D": "Deltoid" }, "Question": "Which muscle paralysis can cause ‘Winging of scapula’?" }
null
64d1c32f-b4b3-4730-a2a8-c825824c1b17
The peritrochanteric fracture is one of the most serious causes of mortality and morbidity in the elderly. Subtrochanteric fractures account for approximately 10-30% of all peritrochanteric fractures, and they affect persons of all ages. 1,2 The subtrochanteric region of the femur is generally recognized to be the area of the femur below the inferior border of the lesser trochanter, extending distally 7.5 cm to the junction of the proximal and middle third of the femur.3 Most frequently, these fractures are seen in two patient populations, namely older osteopenic patients after a low-energy fall and younger patients involved in high-energy trauma.1-3 In elderly patients, minor slips or falls that lead to direct lateral hip trauma are the most frequent mechanism of injury. This age group is also susceptible to metastatic disease that can lead to pathologic fractures. In younger patients, the mechanism of injury is always high-energy trauma, either direct or from axial loading (e.g., a fall from height), which often creates a comminuted fracture.
Orthopaedics
{ "Correct Answer": "All of the the above", "Correct Option": "D", "Options": { "A": "Flexion", "B": "Abduction", "C": "External rotation", "D": "All of the the above" }, "Question": "True about proximal fragment In supratrochantric fracture is" }
null
6661e270-bfeb-47fd-84db-a8335649f1c9
A demonstration is a carefully prepared presentation to show how to perform a skill or procedure. Here a procedure is carried out step by step before an audience. Demonstration is found to have high education value in programmes like teaching a mother the use of oral rehydration therapy at home. Ref: Park 21st edition, page: 803.
Social & Preventive Medicine
{ "Correct Answer": "Demonstration", "Correct Option": "B", "Options": { "A": "Group discussion", "B": "Demonstration", "C": "Lecture", "D": "Flannel graph" }, "Question": "The BEST method for teaching mothers about using ORS is:" }
null
bf0dbdb9-f0ba-4c00-960c-8f7a58d78765
Post coital or emergency contraceptives are, Ethinyl oestradiol Conjugated estrogen Ethinyl oestradiol + Norgestrel Levonorgestrel Mifepristone Copper IUDs Ref: Textbook of Obstetrics by D.C. Dutta, 6th edition, Page 550.
Gynaecology & Obstetrics
{ "Correct Answer": "LNG IUD", "Correct Option": "A", "Options": { "A": "LNG IUD", "B": "Oral Mifepristone", "C": "Oral Levonorgestrel", "D": "Cu-containing IUD" }, "Question": "A female wanted to have an emergency contraception after an unprotected intercourse. Which of these is NOT useful as an emergency contraceptive?" }
null
40475463-bff9-4d47-9def-271d7ca80d6d
Stills disease is a variant of rheumatoid commonly occurring in adults in 20's and 30's. Patients characteristics clinical features are: High spiking fever often up to 40°C. Sore throat Evanescent salmon coloured non pruritic rash, seen on chest & abdomen Lymphadenopathy Pericardial effusion Wrist joint involvement Chances are that you might confuse it with Felty's syndrome so I am giving the important features of both these conditions together
Pathology
{ "Correct Answer": "Rashes", "Correct Option": "B", "Options": { "A": "Prominent kidney involvement", "B": "Rashes", "C": "Positive Rheumatoid factor", "D": "Neutropenia" }, "Question": "A characteristic feature of Still's disease -" }
Urinary bladder
435a8f7a-d981-484e-ab33-696d5860ea3b
PRIMARY BLADDER CALCULI (ENDEMIC BLADDER CALCULI) Mainly seen in underdeveloped countries (Noh Africa, Thailand, Myanmar, Indonesia), in pediatric age group. Most common in children <10 Years, with a peak incidence at 2 to 4 years of age. Related to chronic dehydration and low protein, low phosphate, exclusive milk & high carbohydrate diet. Low phosphate diet Increases urinary ammonium excretion leading to ammonium urate stones Treatent Small stones: Removed or crushed transurethral electrohydraulic lithotripsy or Cystolithotomy. Primary bladder calculi rarely recur after treatment.
Surgery
{ "Correct Answer": "Always associated with recurrence", "Correct Option": "A", "Options": { "A": "Always associated with recurrence", "B": "High incidence in cereal based diet", "C": "Peak incidence in 3 years old children in India", "D": "Most common type is ammonium urate or calcium oxalate" }, "Question": "Which of the following is false regarding endemic bladder stones?" }
Physiological Changes of Pregnancy
7c021870-c90d-4a27-93c5-e0a629acc78b
Glucosuria during pregnancy is not necessarily abnormal. The appreciable increase in glomerular filtration, together with impaired tubular reabsorptive capacity for filtered glucose, accounts in most cases for glucosuria. Though glucosuria is common during pregnancy, the possibility of diabetes mellitus should not be Ignored when it is identified.
Gynaecology & Obstetrics
{ "Correct Answer": "Glucose", "Correct Option": "A", "Options": { "A": "Glucose", "B": "Lactose", "C": "Galactose", "D": "Fructose" }, "Question": "Which of the following is present normally in the urine of a pregnant women in the third trimester and lactation?" }
null
83b407ed-1452-40fc-bf28-1e5120ba340a
Ans. is 'd' i.e., Halitosis The clinical symptoms of acute sinusitis have been classified into major and minor Major Facial pain or pressure Purulent nasal discharge Fever Nasal congestion Nasal obstruction Hyposmia or Anosmia Facial congestion or fullness Minor Headache Cough Fatigue Halitosis Dental pain Ear pain or pressure
ENT
{ "Correct Answer": "Halitosis", "Correct Option": "D", "Options": { "A": "Nasal bluckage", "B": "Facial congeion", "C": "Nasal congestion", "D": "Halitosis" }, "Question": "All are major symptoms of sinusitis except ?" }
General Microbiology (Sterilization and Bacterial Genetics)
5796ec13-1a66-4072-9648-7be79e8308e9
Option a, b, c, d * There are three mechanisms of horizontal gene transfer in bacteria:- 1.Transformation 2. Transduction 3. Conjugation (Most common mechanism), It was discovered first by Lederberg and Tatum. * Conjugation plays an impoant role in the transfer of plasmids coding for antibacterial drug resistance and bacteriocin production . * R factor (or the resistance factor) is a plasmid which has two components. o Resistance transfer factor (F) is the plasmid responsible for conjugational transfer(similar to F factor) o Resistance determinant (r): Codes for resistance to one drug. An R factor can have several r determinants.
Microbiology
{ "Correct Answer": "Conjugation", "Correct Option": "D", "Options": { "A": "Transformation", "B": "Transduction", "C": "Lysogenic conversion", "D": "Conjugation" }, "Question": "Which of the following is the most widespread method of genetic transfer among bacteria?" }
General anatomy
b2a15042-9ed0-417c-b113-e79f5d1c25fe
steps: (1) migration and proliferation of fibroblasts into the site of injury and (2) deposition of ECM proteins produced by these cells. The recruitment and activation of fibroblasts to syn- thesize connective tissue proteins are driven by many growth factors, including PDGF, FGF-2 (described earlier), and TGF-b. The major source of these factors is inflamma- tory cells, paicularly macrophages, which are present at sites of injury and in granulation tissue. Sites of inflamma- tion are also rich in mast cells, and in the appropriate chemotactic milieu, lymphocytes may be present as well. Each of these cell types can secrete cytokines and growth factors that contribute to fibroblast proliferation and activation. As healing progresses, the number of proliferating fibroblasts and new vessels decreases; however, the fibro- blasts progressively assume a more synthetic phenotype, so there is increased deposition of ECM. Collagen synthe- sis, in paicular, is critical to the development of strength in a healing wound site. As described later, collagen syn- thesis by fibroblasts begins early in wound healing (days 3 to 5) and continues for several weeks, depending on the size of the wound. Net collagen accumulation, however, depends not only on increased synthesis but also on diminished collagen degradation (discussed later). Ulti- mately, the granulation tissue evolves into a scar composed of largely inactive, spindle-shaped fibroblasts, dense collagen, fragments of elastic tissue, and other ECM com- ponents (Fig. 2-30, B). As the scar matures, there is proA A gressive vascular regression, which eventually transforms the highly vascularized granulation tissue into a pale, largely avascular scar. Growth Factors Involved in ECM Deposition and Scar Formation Many growth factors are involved in these processes, including TGF-b, PDGF, and FGF. Because FGF also is involved in angiogenesis, it was described earlier. Here we briefly describe the major propeies of TGF-b and PDGF. * Transforming growth factor-b (TGF-b) belongs to a family of homologous polypeptides (TGF-b1, -b2, and -b3) that includes other cytokines such as bone morphogenetic proteins. The TGF-b1 isoform is widely distributed and is usually referred to as TGF-b. The active factor binds to two cell surface receptors with serine-threonine kinase activity, triggering the phosphorylation of transcription factors called Smads. TGF-b has many and often oppo- site effects, depending on the cell type and the metabolic state of the tissue. In the context of inflammation and repair, TGF-b has two main functions: TGF-b stimulates the production of collagen, fibro- nectin, and proteoglycans, and it inhibits collagen degradation by both decreasing proteinase activity and increasing the activity of tissue inhibitors of pro- teinases known as TIMPs (discussed later on). TGF-b is involved not only in scar formation after ref Robbins 9/e p83
Anatomy
{ "Correct Answer": "Myeloperoxidase", "Correct Option": "B", "Options": { "A": "Tumor necrosis factor", "B": "Myeloperoxidase", "C": "Interferons", "D": "Interleukins" }, "Question": "Which of the following is not an inflammatory mediator" }
null
7cee84e8-c62b-47fa-ad8b-b6b8cf0560d0
"Acute muscle dystonia caused by antiemetic-antipsychotic drugs is promptly relieved by parenteral promethazine or hydroxyzine." This is based on the central anticholinergic action of the drugs. Promethazine is a first-generation anti-histaminic which has a maximum penetration of blood-brain barrier and maxi­mum anticholinergic activity.
Pharmacology
{ "Correct Answer": "Promethazine", "Correct Option": "B", "Options": { "A": "Pheniramine", "B": "Promethazine", "C": "Chlorpromazine", "D": "Prochlorperazine" }, "Question": "A drug given for metoclopramide induced dystonic reaction is :" }
Breast Milk & Breast Feeding
8e18e69d-c81f-4039-9c95-310b07c39dda
Mother's milk has more lactose as compared to cow's milk.
Pediatrics
{ "Correct Answer": "Lactose", "Correct Option": "A", "Options": { "A": "Lactose", "B": "Vitamin D", "C": "Proteins", "D": "Fat" }, "Question": "Compared with cow's milk, mother's milk has more?" }
null
56191ff4-6fcc-4c6f-9344-111dfc8fac69
null
Dental
{ "Correct Answer": "Mummifying agent", "Correct Option": "D", "Options": { "A": "Obtundant", "B": "Astringent", "C": "Haemostatic", "D": "Mummifying agent" }, "Question": "When pulp cannot be extirpated in narrow canals, which of the following can be used" }
null
38b99eb5-0ca1-4025-a359-45dfb85913a3
In a patient with CSOM, persistent ear discharge with or without deep seated pain in spite of an adequate coical or modified mastoidectomy points towards petrositis. Spread of infection from middle ear and mastoid to the petrous pa of temporal bone is petrositis it can also involve adjacent 5th cranial nerve and 6" cranial nerve when it produces classical triad of symptoms - 6th nerve palsy, retro orbital pain (5th nerve) and persistent discharge from the ear, known as Gradenigo's syndrome Treatment Adequate drainage is the mainstay of treatment along with specific antibiotic therapy. Modified radical or radical mastoidectomy is often required if not done already. The fistulous tract should be identified, curetted and enlarged to provide free drainage.
ENT
{ "Correct Answer": "Petrositis", "Correct Option": "C", "Options": { "A": "Diffuse serous labyrinthitis", "B": "Purulent labyrinthitis", "C": "Petrositis", "D": "Latent mastoiditis" }, "Question": "A man presented with persistent ear pain and discharge, retro-orbital pain and modified radical mastoidectomy was done to him. Patient comes back with persistent discharge, what is your diagnosis?" }
null
0cecd862-910f-4395-96c2-4e6a0c3945e4
Verrucuous epidermal nevus Linear verrucuous lesions, with characteristic histopathological feature of granular degeneration of the epidermis ours the diagnosis of verrucous epidermal nevus. Epidermal nevus Epidermal nevi are hamaomas that are characterized by hyperplasia of the epidermis and adnexal structures. These nevi may be classified into a number of distinct variants which are based on clinical morphology, extent of involvement and the predominant epidermal structure in the lesion. Variants of the epidermal nevi are ? - Verrucuous epidermal nevus - Nevus sebaceous - Nevus comedonicus - Eccrine nevus - Apocrine nevus - Becker's nevus - White sponge nevus Verrucuous epidermal nevus Verrucuous epidermal ,nevus consists of hyperplasia of the surface epidermis and typically appears as verrucuous papules that coalasce to form well demarcated, skin colored to brown, papillomatous plaque. Most lesions are present at bih and develop during infancy. They enlarge slowly during childhood and generally reach a stable size at adolescence. Lesions may be localized or diffuse. Linear configurations are common especially on the limbs and may follow skin tension lines or Blaschko's lines. The salient histological features are ? Perinuclear vacuolization of the cells in the stratum spinosum and stratum granulosum. Irregular cellular boundaries peripheral to the vacuolization and increased number of irregularly :,aped large keratohyaline granules. Compact hyperkeratosis in stratum corneum. Darner white disease Autosomal dominant disease. Males and females are equally affected. Daffier white disease is not present at bih and usually begins in the first or second decade. Characteristic sites of prediliction are the face, forehead, scalp, chest and the hack (seborrhic sites). Clinical features consists of way papules and plaques in (seborrhic sites). Histology shows suprabasal acantholysis in epidermis with dyskeratotic cells. Incontinentia pigmentii X linked disease (so only seen in females) Lesions are present along the Blaschko lines, which are initially vesicular, that later on turns into verrucuous lesions and hyperpigmented stages. Common histological features are : - Hverkeratosis - Eosinophilic spongiosis of epidermis - Basal cell degeneration - Pigment incontinenti
Skin
{ "Correct Answer": "Verrucous epidermal nevus", "Correct Option": "C", "Options": { "A": "Incontinenta pigmenti", "B": "Delayed hypersensitivity reaction", "C": "Verrucous epidermal nevus", "D": "Linear darriers disease" }, "Question": "Child presents with linear verrucous plaques on the trunk with vacuolisation of keratinocytes in S.Spinosum and S.Granulosum. Diagnosis is ?" }
null
440ced06-5425-41ca-9509-5b64d2082026
null
Surgery
{ "Correct Answer": "Condylar fracture", "Correct Option": "D", "Options": { "A": "Zygomatic complex", "B": "Temporal bone", "C": "Orbital floor fracture", "D": "Condylar fracture" }, "Question": "A swelling behind the ear suggest fracture of:" }
null
6c110742-768c-4dbd-8d12-7fa08d8d7d9c
X-ray abdomen in lateral decubitus
Radiology
{ "Correct Answer": "X-ray abdomen in lateral decubitus", "Correct Option": "D", "Options": { "A": "Chest X-ray", "B": "X-ray abdomen in supine position", "C": "X-ray abdomen in supine position", "D": "X-ray abdomen in lateral decubitus" }, "Question": "Best test to detect pneumoperitoneum is:" }
G.I.T
655de91c-95e0-4166-8a2a-d04c42d55729
IEL are6 a distinctive population of T cells dispersed among the luminal epithelial cells. paicularly in the small intestine there is a predominantly of CD8+T cells
Anatomy
{ "Correct Answer": "T cell", "Correct Option": "B", "Options": { "A": "B cell", "B": "T cell", "C": "Plasma cells", "D": "Basopils" }, "Question": "In the intraepthielial region of the mucosa of intestine the predominant cell population is that of" }
Forearm wrist and hand injuries
a0e1a2d9-7a9e-4457-8dd7-925d12f31a25
scapholunate dislocation : * Most common ligamentous instability of the wrist * Patients may have high degree of pain despite apparently normal radiographs * Physicians should suspect this injury if patient has wrist effusion and pain seemingly out of propoion to the injury * If improperly diagnosed can lead to chronic pain * Located proximal axial line from 3rd metacarpal Scapholunate Dissociation-Diagnosis * Exam -- Watson&;s test -- Scaphoid shuck test -- Pain/swelling over dorsal wrist, proximal row * Imaging -- Plain films: >3mm difference on clenched fist view -- Scaphoid ring sign Scapholunate Dissociation Treatment * If discovered within 4 weeks, surgery * After 4 weeks, conservative treatment reas -- Bracing -- NSAIDS -- Consider evaluation by hand surgery to confirm no surgery needed ref : maheswari 9th ed
Orthopaedics
{ "Correct Answer": "Carpal dislocation", "Correct Option": "B", "Options": { "A": "Keinbock's disease", "B": "Carpal dislocation", "C": "Calcaneal disorder", "D": "Hip trauma" }, "Question": "Terry Thomas sign is seen in" }
Conducting System of Hea
7a80dd43-865e-46ac-ada9-e531c3ba686a
After MI, there is failure of Na+-K+ pump resulting in NCX failure Thus intracellular Ca+2 increases Now when perfusion is established (nutrients are available), because of increased ICF Ca+2, cardiac fibers contract very strongly Already muscle fibers are fragile due to M.I, now this contraction results in fuher damage. This is basic reason for "reperfusion injury".
Physiology
{ "Correct Answer": "Increased ICF", "Correct Option": "C", "Options": { "A": "Generation of free radicals", "B": "Extension of the ischemic zone", "C": "Increased ICF", "D": "Increased ECF" }, "Question": "The basic reason for \"reperfusion injury\" to the myocardium is:" }
null
2e35d2c0-424b-4fb3-8df8-63430419fbc7
null
Dental
{ "Correct Answer": "Third molars", "Correct Option": "D", "Options": { "A": "Lateral incisors", "B": "Permanent canines", "C": "Permanent central incisors", "D": "Third molars" }, "Question": "The maxillary teeth which have single antagonist are:" }
G.I.T.
bdcb31fe-c6de-4120-ae58-4eecc6e8888c
Peutz-Jeghers syndrome is an autosomal dominant, hereditary disorder characterized by intestinal hamartomatous polyps and mucocutaneous melanin pigmentation, which is particularly evident on the face, buccal mucosa, hands, feet, and perianal and genital regions. The polyps seen in Peutz-Jeghers syndrome are hamartomatous, characterized by a branching network of smooth muscle fibers continuous with the muscularis mucosa that support the glandular epithelium of the polyp. Congenital teratoma (choice A) does not involve the intestine. The other choices are principally colonic polyps that derive from the luminal epithelium.Diagnosis: Gastrointestinal polyp, Peutz-Jeghers polyp
Pathology
{ "Correct Answer": "Peutz-Jeghers polyp", "Correct Option": "C", "Options": { "A": "Congenital teratoma", "B": "Hyperplastic polyp", "C": "Peutz-Jeghers polyp", "D": "Tubular adenoma" }, "Question": "A 5-year-old girl is brought to the physician after her parents noticed red blood in her stool. Physical examination reveals mucocutaneous pigmentation. Small bowel radiography discloses multiple, small- to medium-sized polyps that are diagnosed pathologically as hamartomas. Which of the following is the most likely diagnosis?" }
Nutrition and health
a2bce9c5-44fc-444b-9a40-d2f7fc02a0db
The single most sensitive tool for evaluating the iron status is by measurement of serum ferritin. Hemoglobin concentration is relatively insensitive. REF. PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICAL 21ST EDITION. PAGE NO - 623
Social & Preventive Medicine
{ "Correct Answer": "S. Ferritin", "Correct Option": "C", "Options": { "A": "S. Iron", "B": "Total iron binding capacity", "C": "S. Ferritin", "D": "S. Haemoglobin concentration" }, "Question": "First indices to change in iron deficiency anemia is -" }
Pediatric dermatology
a446fbdd-d3a9-4b22-bf10-aa7f2f948c78
Child with right sided po-wine stain- seen in sturge weber syndrome. Features of sturge weber syndrome: S- Seizure T- Trigeminal distribution of po wine stain U- Unilateral weakness R- Retardation( mental retardation) G-Glaucoma E- Buphthalamos here, glaucoma is associated with surface ocular vascular malformations .
Dental
{ "Correct Answer": "Glaucoma", "Correct Option": "C", "Options": { "A": "Leg length discrepancy", "B": "Airway involvement", "C": "Glaucoma", "D": "Growth hormone deficiency" }, "Question": "Which of the following is associated with the disease pathology seen in this child?" }
null
979d83d1-92f8-4224-a5ee-342f0c01138f
null
Dental
{ "Correct Answer": "Simultaneously etch and prime dentin and enamel", "Correct Option": "A", "Options": { "A": "Simultaneously etch and prime dentin and enamel", "B": "Etches enamel only", "C": "Only bonds to enamel", "D": "Only removes smear layer" }, "Question": "Self etching primers" }
Cornea
d966d76a-613c-45a1-af6f-084422083130
Penetrating keratoplasty has to be done in cases of deep corneal scar or hydrops. SURGICAL MODALITIES FOR KERATOCONUS Keratoplasty for Keratoconus DALK (deep anterior Lamellar keratoplasty): when > 1/2 of stroma is involved. ALTK (Anterior lamellar therapeutic keratoplasty) : When less than 1/2 of stroma is involved. Penetrating Keratoplasty: When full thickness of cornea is involved as in hydrops with scar. INTRASTROMAL CORNEAL RING SEGMENTS Reduce corneal steepening Made of PMMA. Femtolaser is used to make tunnel in cornea. Used in Pellucid Marginal Degeneration, post LASIK ectasia and keratoconus.
Ophthalmology
{ "Correct Answer": "Penetrating Keratoplasty", "Correct Option": "A", "Options": { "A": "Penetrating Keratoplasty", "B": "Endothelial lamellar Keratoplasty", "C": "Deep anterior lamellar keratoplasty", "D": "Collagen cross linking" }, "Question": "Patient came with hydrops and scarring of cornea. What would be the treatment modality you would opt for him:" }
Communicable diseases
40f8775f-ba22-451b-80d6-fa93674bc7e2
Incubation period of mumps varies from 2 to 4 weks, usually 14- 18 days Reference : Park&;s Textbook of preventive and social medicine, 24th edition.Pg no.162
Social & Preventive Medicine
{ "Correct Answer": "12-24 days", "Correct Option": "C", "Options": { "A": "4-5 days", "B": "7-15 days", "C": "12-24 days", "D": "50 days" }, "Question": "Incubation period of Mumps -" }
null
24203aa2-0e3b-476c-b8a5-7dfe29c6e74d
Ans. A: Cremasteric veinVaricocelectomy, the surgical correction of a varicocele, is performed on an outpatient basis.The three most common approaches are inguinal (groin), retroperitoneal (abdominal), and infrainguinal/subinguinal (below the groin).Possible complications of this procedure include hematoma (bleeding into tissues), infection, or injury to the scrotal tissue or structures.In addition, injury to the aery that supplies the testicle may occur.An alternative to surgery is embolization, a non-invasive treatment for varicocele.Embolization is an effective treatment for post-surgical varicoceles.
Surgery
{ "Correct Answer": "Cremasteric vein", "Correct Option": "A", "Options": { "A": "Cremasteric vein", "B": "Dorsal vein of penis", "C": "Internal pudendal vein", "D": "Pampiniform plexus" }, "Question": "Drainage of venous blood from testes following division of testicular vein for treatment of varicocele is by: March 2009" }
null
2f450319-b190-46b6-9de9-f5645e019e33
Moore suggested a classification of omphalocele into types 1, 2 and 3 with the diameters of < 2.5 cm, 2.5 to 5 cm and > 5 cm respectively.
Surgery
{ "Correct Answer": "2.5", "Correct Option": "B", "Options": { "A": "0.5", "B": "2.5", "C": "3.5", "D": "4.5" }, "Question": "In Moore's classification of omphalocole (examphalos), type I umbilical defect is less than ________ cm." }
null
9e9fee42-68a2-4df8-a01b-abb800da69cb
null
Pathology
{ "Correct Answer": "Conservative surgery", "Correct Option": "D", "Options": { "A": "Surgical excision", "B": "Removal of adjacent teeth", "C": "Irradiation of the Lesion", "D": "Conservative surgery" }, "Question": "A patient with fibrous dysplasia can be treated by" }
Environment and health
fe85d6f0-28d1-413d-8f6e-2bf1f7bafe21
Hard ticks transmit the following disease Tick typhus Viral encephalitis Viral fever Viral hemorrhagic fever Tularemia KFD Tick paralysis Human babesiosis Soft tick transmits Q fever Relapsing fever KFD(outside India) Park's Textbook of Preventive and Social Medicine, 25th edition, Page No. 840
Social & Preventive Medicine
{ "Correct Answer": "Tick", "Correct Option": "B", "Options": { "A": "Rat flea", "B": "Tick", "C": "Mite", "D": "None" }, "Question": "Lyme disease is transmitted by -" }
Endocrinology
36a78af0-82a3-4d63-9dbf-b8c057217e7c
The diagnosis is secondary hyperparathyroidism as a consequence of the chronic renal disease. Calcium deposits are seen in the periarticular areas of the fourth and fifth metacarpophalangeal, third proximal interphalangeal, and fourth distal interphalangeal joints. There is slight soft tissue swelling, especially, of the fourth and fifth metacarpophalangeal joints. Calcification in scleroderma is subcutaneous in location. In gout if monosodium urate is deposited it could appear as a soft tissue mass.
Medicine
{ "Correct Answer": "secondary hyperparathyroidism", "Correct Option": "C", "Options": { "A": "scleroderma", "B": "gout", "C": "secondary hyperparathyroidism", "D": "pseudogout" }, "Question": "A 35-year-old woman, on hemodialysis for chronic renal disease, complains of pain in the hands. On examination, the joints are normal with no inflammation or tenderness on palpation. Lab values reveal a low calcium, high phosphate, and high PTH level. What is the most likely diagnosis? (See Figure below.)" }
null
492d4dca-0785-455b-acdd-57b32b8f6947
null
Pathology
{ "Correct Answer": "Amyloid", "Correct Option": "B", "Options": { "A": "Mucin", "B": "Amyloid", "C": "Glycolipid", "D": "Phospholipid" }, "Question": "Hyaline in islets of Langerhans resemble -" }
Drowning
a9f22898-cc6a-4ad0-af7c-729d13827f21
Emphysema aquosum is a sign of wet drowning. Drowning fluid actually penetrates alveolar walls to enter the tissues and the blood vessels. This has been described as emphysema aquosum. Cause of death in wet drowning: Disruption of pulmonary surfactant Dry drowning: Water does not enter the lungs, but death results from: Immediate sustained laryngeal spasm Cardiac arrest due to vagal inhibition
Forensic Medicine
{ "Correct Answer": "Wet drowning", "Correct Option": "B", "Options": { "A": "Dry drowning", "B": "Wet drowning", "C": "Immersion syndrome", "D": "Secondary drowning" }, "Question": "Emphysema aquosum is associated with?" }
null
6b2d7107-6914-4bb7-a018-2bff8b75adbd
Ans. is 'b' i.e., Can be mixed with saline o While phenytoin cannot be injected in a drip of glucose solution, fosphenytoin can be injected with saline and glucose.
Pharmacology
{ "Correct Answer": "Can be mixed with saline", "Correct Option": "B", "Options": { "A": "Can be used in absence seizures", "B": "Can be mixed with saline", "C": "Can be given orally", "D": "It is the drug of choice for myoclonic seizures" }, "Question": "Fosphenytoin different from phenytoin in which of the following-" }
Haematology
dd8b902e-eeb4-4f92-85b0-1c362b10d777
Robbins basic pathology 8th edition, page no 423, Answer is option3, post hemorrhagic anemia Post Hemorrhagic anemia is normocytic and normochromic. With chronic blood loss, iron stores are gradually depleted. Iron is essential for hemoglobin synthesis and effective eeythropoiesis, and it's deficiency thus leads to chronic anemia of underproduction.
Pathology
{ "Correct Answer": "Post hemorrhagic anemia", "Correct Option": "C", "Options": { "A": "Vitamin B12 deficiency", "B": "Hemolytic anemia", "C": "Post hemorrhagic anemia", "D": "Anemia of chronic disease" }, "Question": "Macrocytic anemia is seen in all EXCEPT -" }
Infection
bb21518a-3cea-45de-b40f-c3db7315194b
The most common presentations of the lymphatic filariases are asymptomatic (or subclinical) microfilaremia, hydrocele , acute adenolymphangitis (ADL), and chronic lymphatic disease. If there is obstruction of the retroperitoneal lymphatics, increased renal lymphatic pressure leads to rupture of the renal lymphatics and the development of chyluria, which is usually intermittent and most prominent in the morning. (Harrison's Principles of internal medicine, 20th edition, page 1747)
Medicine
{ "Correct Answer": "Filaria", "Correct Option": "C", "Options": { "A": "Carcinoma", "B": "Tuberculosis", "C": "Filaria", "D": "Malaria" }, "Question": "Chyluria is due to-" }
Metabolic disorders - 1
0f06eb10-64f5-41bc-bcac-0092825873ed
Fluorosis: Excessive deposition of fluorine occurs in bone and soft tissues. Fluorine stimulates osteoblastic activityand fluoroappatite crystals are laid down in bone which are resistant to osteoclastic resorption. This leads to calcium retention, impaired mineralization and secondary hyperparathyroidism. Interosseousmembrane ossification is a diagnostic radiological finding in skeletal fluorosis The characteristic pathology involves Sub-periosteal new bone formation, Osteosclerosis(Most commonly seen veebrae, ribs and pelvis) Hyperostosis at the bony attachments of ligaments, tendons and fascia.
Orthopaedics
{ "Correct Answer": "Fluoroappatite crystals are resistant to osteoclasts", "Correct Option": "B", "Options": { "A": "Fluorine increases PTH levels by direct action", "B": "Fluoroappatite crystals are resistant to osteoclasts", "C": "Fluorine decreases vitamin D levels", "D": "Fluorine erodes bone, thereby decreasing bone density" }, "Question": "Which of the following is true about pathophysiology of skeletal fluorosis?" }
Stomach & Duodenum
f3141bf3-7ab9-407e-ab73-6cd9800a3b8b
Ans. (a) Perforation of duodenum* This is a clear-cut case of drug induced ulcer and perforation - Duodenal ulcer perforation* Features are diffuse abdominal pain with right iliac fossa pain due to tracking of pus in right colic gutter - Valentino Syndrome* Obliteration of liver dullness* Board like rigidity
Surgery
{ "Correct Answer": "Perforation of duodenum", "Correct Option": "A", "Options": { "A": "Perforation of duodenum", "B": "Diverticulitis", "C": "Gastroenteritis", "D": "Enteric perforation" }, "Question": "Patient is on Autocoids for 1 year now complains of severe pain Epigastrium relieved by antacid drugs. He complaints of Right Iliac fossa pain and loss of liver dullness. Diagnosis is:" }
All India exam
455fe350-422c-48c0-a567-6594893b2ef0
.
Pathology
{ "Correct Answer": "The acrosome reaction", "Correct Option": "A", "Options": { "A": "The acrosome reaction", "B": "The zona reaction", "C": "The perivitelline space", "D": "Pronuclei formation" }, "Question": "Upon contact between the sperm head and the zona pellucida, penetration of the sperm into the egg is allowed because of" }
Lipoproteins
1b5f7a7d-4d04-45cd-93c1-655d411b2ffd
As excess of carbohydrates are conveed to fat in the body (liver) which eventually gets packed into VLDL so, VLDL represents the amount of fat production in the body, or in other words, it also represent excess dietary carbohydrate intake. While Chylomicrons represents the externally taken fats. Function Lipoproteins Lipoprotein rich in triglyceride Lipoprotein with least electrophoretic mobility Transpoer of dietary (exogenous) triglycerides & Cholesterol Chylomicrons Transpoer of endogenous triglycerides VLDL Transpos endogenous Cholesterol from Liver to Peripheral tissue. LDL Lipoprotein rich in apolipoproteins Transpos excess Cholesterol from Peripheral tissue to Liver called as reverse cholesterol transpo HDL has the highest electrophoretic mobility and least lipid content. HDL paicles are the densest. On electrophoresis, HDL moves fahest on electrophoretic plate towards the anode. HDL Lipoprotein resembling plasminogen Lp(a)
Biochemistry
{ "Correct Answer": "VLDL", "Correct Option": "B", "Options": { "A": "Chylomicron", "B": "VLDL", "C": "IDL", "D": "HDL" }, "Question": "A person switches from high fat diet to low fat diet with compensatory increase in carbohydrates to maintain the same calories. Which of the following fat component will be increased ?" }
null
df6ffed5-db98-4145-b97d-1205ce9fc8dd
Ans. is 'c' i.e., Pyloric antrum
Surgery
{ "Correct Answer": "Pyloric antrum", "Correct Option": "C", "Options": { "A": "Fundus", "B": "Cardia", "C": "Pyloric antrum", "D": "Body" }, "Question": "G-cells are present mostly in- G-cells are present mostly in-" }
Immunity
5205bc00-4502-4d71-8dd9-16dca58c1f7a
(B) T-cells[?]Role of T cells in RAoProminent T-cell infiltrate in RA synoviumoGenetic similarities between RA patients-Specific human leukocyte antigen (HLA)-DR genes - HLA DR4, DR14 and DR1oShared Epitope: The third hypervariable region of DR b chains, especially amino acids 70 through 74.oCD4+ T helper (Th) cells may initiate the autoimmune response in RA by reacting with an arthritogenic agent, perhaps microbial or a self-antigenoSynovial lining or intimal layer: Normally, this layer is only 1-3 cells thick. In RA, this lining is greatly hypertrophied (8-10 cells thick).oPrimary cell populations in this layer are fibroblasts and macrophages.
Pathology
{ "Correct Answer": "T-cells", "Correct Option": "B", "Options": { "A": "B cells", "B": "T-cells", "C": "NK-cells", "D": "Both B & T Cells" }, "Question": "Which type of cells are prominently infiltrated in Rheumatoid arthritis?" }
Spleen
aa9d2f72-4c71-42fe-ac34-d81c256916fc
Causes of isolated splenic metastasis: Carcinoma Ovary (27%) > Colorectal carcinoma (26%) > Uterine cancer (17%) MC primary for metastasis of spleen: Malignant melanoma (30-50%) > Ca Breast (21%) > Ca lung (18%)
Surgery
{ "Correct Answer": "Carcinoma ovary", "Correct Option": "C", "Options": { "A": "Carcinoma pancreas", "B": "Carcinoma stomach", "C": "Carcinoma ovary", "D": "Carcinoma cervix" }, "Question": "Most common cause of isolated splenic metastasis is:" }
null
bcba6895-89ca-4701-98c4-720de400d0c6
A i.e. Cyanide
Biochemistry
{ "Correct Answer": "Cyanide", "Correct Option": "A", "Options": { "A": "Cyanide", "B": "Carbon dioxide", "C": "Chocolate", "D": "Carbonated beverages" }, "Question": "Cellular oxidation is inhibited by :" }
null
d0ac2334-7071-4716-9233-6a2e4b11167e
Content of Orbit: Eyeball - Eyeball occupies anterior 1/3rd of orbit. Fascia - Orbital and bulbar fascia. Muscles - Extraocular and intraocular muscles. Vessels - Ophthalmic artery, superior and inferior ophthalmic veins and lymphatics. Nerves - Optic, oculomotor, trochlear and abducent, branches of ophthalmic and maxillary nerves and sympathetic nerves. Lacrimal gland. Orbital fat.
Anatomy
{ "Correct Answer": "All of the Above", "Correct Option": "D", "Options": { "A": "Orbital and bulbar fascia", "B": "Abducent nerve", "C": "Superior Ophthalmic Veins", "D": "All of the Above" }, "Question": "Which of the following includes the contents of the orbit" }
C.V.S
09a25352-1655-422e-954b-b5fa0e6497a0
Therefore, a defining characteristic of aoic regurgitation is an increase in aoic pulse pressure (systolic minus diastolic pressure). ... Early in the course of regurgitant aoic valve disease, there is a large increase in left ventricular end-diastolic pressure and left atrial pressure.pulse pressure usually between 75-90 mm/hg Ref Davidson 23rd edition pg 450
Medicine
{ "Correct Answer": "75-90 mm Hg", "Correct Option": "D", "Options": { "A": "30-45mmHg", "B": "45-60mmHg", "C": "60-75 mmHg", "D": "75-90 mm Hg" }, "Question": "Pulse pressure in severe aoic regurgitation is equal to-" }
null
d48fc7eb-671f-4f5c-bdec-6cfc614d3ffc
Placental exchanges that take place occur according to different mechanisms. Simple diffusion is the movement of molecules of gas and water from a high concentration to a low concentration. Iodine readily crosses the placental barrier. Active transpo is another method. This method transpos specific molecules across a membrane or against a concentration gradient which requires energy (ATP) (i. e. Ca++, Na +, and K+). Endocytosis is the method by which the macromolecules are captured by cell microvilli. Leakage is difficult to understand, but it has to do with the connections or like connections between fetal and maternal blood. Ref: Molina P.E. (2013). Chapter 9. Female Reproductive System. In P.E. Molina (Ed), Endocrine Physiology, 4e.
Physiology
{ "Correct Answer": "Exocytosis", "Correct Option": "D", "Options": { "A": "Simple diffusion", "B": "Active transpo", "C": "Endocytosis", "D": "Exocytosis" }, "Question": "Transplacental exchanges that take place are essential to the well being of the fetus. Which of those listed below is NOT a method?" }
null
5d81196e-b944-48a1-ae0e-3ecdcae74003
Superficial Inguinal Lymph NodesThe horizontal groupThe medial members of the group receive superficial lymph vessels from the anterior abdominal wall below the level of the umbilicus and from the perineum. The lymph vessels from the urethra, the external genitalia of both sexes (but not the testes), and the lower half of the anal canal are drained by this route.The lateral members of the group receive superficial lymph vessels from the back below the level of the iliac crests.The veical group lies along the terminal pa of the great saphenous vein and receives most of the superficial lymph vessels of the lower limb.The efferent lymph vessels from the superficial inguinal nodes pass through the saphenous opening in the deep fascia and join the deep inguinal nodes.Deep Inguinal Lymph NodesThe deep nodes are located beneath the deep fascia and lie along the medial side of the femoral vein; the efferent vessels from these nodes enter the abdomen by passing through the femoral canal to lymph nodes along the external iliac aery Lymphatic Drainage of the PenisFrom most of the penis, lymph drains into the superficial inguinal lymph nodes.Vessels from the glans penis drain into the deep inguinal lymph nodes.
Anatomy
{ "Correct Answer": "Glans penis", "Correct Option": "C", "Options": { "A": "Urethra", "B": "Anal canal below the pectinate line", "C": "Glans penis", "D": "Perineum" }, "Question": "Superficial inguinal lymph nodes drain from all of the following except:" }
Cytotoxic Anticancer Drugs
11aa7d32-e159-4432-823e-85d8ee9f8c2a
FLAGELLATED DERMATITIS: It is characterised by pruritic, erythematous, linear streaks that resemble whiplash marks, hence the name flagellated. Bleomycin is metabolized by an enzyme hydrolase. This enzyme is deficient in skin and lungs. Therefore, the major adverse effects of bleomycin is related to skin (flagellated dermatitis) and lungs (pulmonary fibrosis) OTHER CAUSES OF FLAGELLATED DERMATITIS: DRUGS: BLEOMYCIN, DOCETAXEL, BENDAMUSTINE RHEUMATOLOGICAL CAUSES: DERMATOMYOSITIS, ADULT ONSET STILL'S DISEASE TOXINS: SHIITAKE MUSHROOMS
Pharmacology
{ "Correct Answer": "Bleomycin", "Correct Option": "D", "Options": { "A": "Cisplatin", "B": "L-asparginase", "C": "Doxorubicin", "D": "Bleomycin" }, "Question": "Which of the following anticancer drug can cause flagellated dermatitis?" }
null
1e0271c4-2979-4f53-8cfe-119e0022b265
null
Pathology
{ "Correct Answer": "First nine months of life", "Correct Option": "A", "Options": { "A": "First nine months of life", "B": "First two years of life", "C": "First month of life", "D": "Two or three years of life" }, "Question": "Hypoplastic defects in permanent central and lateral incisors are likely to result due to severe illness or other factors during:" }
null
9713b812-2bf3-4513-b009-37e6e86f52f9
As the eighth nerve schwannoma grows, it extends into the posterior fossa to occupy the angle between the cerebellum and pons (cerebellopontine angle). In this lateral position, it is so situated as to compress the seventh, fifth, and less often the ninth and tenth cranial nerves, which are implicated in various combinations. Later it displaces and compresses the pons and lateral medulla and obstructs the CSF circulation.
ENT
{ "Correct Answer": "VIII", "Correct Option": "C", "Options": { "A": "IX", "B": "VI", "C": "VIII", "D": "X" }, "Question": "The commonest cranial nerve involved in acoustic neuroma is:" }
Epidemiology
1955dbdc-2d6c-43cc-adb1-097d8d183d0c
Ans: b (Primary case) Ref: Park, 19th ed, p. 90The term primary case refers to the first case of a communicable disease introduced into the population unit being studied.The term index case refers to the first case to come to the attention of the investigator; it is not always the primary case. Secondary cases are those developing from contact with primary case.
Social & Preventive Medicine
{ "Correct Answer": "Primary case", "Correct Option": "B", "Options": { "A": "Index case", "B": "Primary case", "C": "Initial case", "D": "Reference case" }, "Question": "The first case introduced into the population group to be studied is called:" }
Endocrinology
80e64981-fab4-4f2d-bbfe-23f5dd405386
Answer is option 2, antibody to thyroid receptors. Thyrotropin receptor (TSHR) antibodies that stimulate the thyroid (TSAb) cause Graves' hypehyroidism and TSHR antibodies which block thyrotropin action (TBAb) are occasionally responsible for hypothyroidism. Unusual patients switch from TSAb to TBAb (or vice versa) with concomitant thyroid function changes. We have examined case repos to obtain insight into the basis for "switching."
Pathology
{ "Correct Answer": "Antibody to thyroid cell receptors", "Correct Option": "B", "Options": { "A": "Antibody to thyroid globulin", "B": "Antibody to thyroid cell receptors", "C": "Antibody to thyroxine", "D": "Antibody to thyroid cells" }, "Question": "Long thyroid stimulating agent is" }
null
9bb3f0f5-613a-4dd6-8597-dfa0db03d80b
B i.e. Isoflurane
Anaesthesia
{ "Correct Answer": "Isoflurane", "Correct Option": "B", "Options": { "A": "Halthane", "B": "Isoflurane", "C": "Sevoflurane", "D": "Desflurane" }, "Question": "Pungent volatile anesthetic agents are:" }
Head Injury
44b6fdad-e127-4e7a-a931-20ff71967cb4
Ans. a. Minimum = 3. Maximum = 15 (Ref: Harrison 19/e p1730, 18/e p3381-3382; Sabiston 19/e p1894; Schwartz 9/e p1522; Bailey 26/e p312. 25/e p301. 302)In Glasgow Coma Scale (GCS). maximum score is 15 and minimum score is 3.Glasgow Coma Scale (GCS)Eye OpeningVerbal responseBest Motor responseSpontaneous4Oriented5Obeys commands6To loud voice3Confused, disoriented4Localizes pain5To pain2Inappropriate words3Flexion (withdrawal) to pain)4No response1Incomprehensible sounds2Abnormal flexion posturing3 No response1Extension posturing2 No response1Maximum score-15Q. minimum score-3Q.Best predictor of outcome: Motor responseQPatients scoring 3 or 4 have an 85% chance of dying or remaining vegetative, while scores above 11 indicate only a 5-10% likelihood of deathQ
Surgery
{ "Correct Answer": "Minimum = 3, Maximum = 15", "Correct Option": "A", "Options": { "A": "Minimum = 3, Maximum = 15", "B": "Minimum = 0, Maximum = 13", "C": "Minimum = 0, Maximum = 15", "D": "Minimum = 3, Maximum = 18" }, "Question": "What are the minimum and maximum possible values of Glasgow Coma Score?" }
null
ae8cb5b6-b8e6-467c-8498-03f45c7cd626
Ans: B i.e. DuodenumSite of absorptionStomach is the site of absorption of water and alcoholDuodenum is the site of absorption of iron and calciumIleum is the site of absorption of vitamin B12 and bile salt
Physiology
{ "Correct Answer": "Duodenum", "Correct Option": "B", "Options": { "A": "Stomach", "B": "Duodenum", "C": "Ileum", "D": "Duodenum + Jejunum" }, "Question": "Iron is absorbed in: March 2012" }
Injuries
9c2aada7-eb94-4d00-b2ee-06508fad8e71
Ans. is 'b' i.e., Beating of feet * Beating may be of following types -i) Falanga (Falolka/Baatinada) : Beating of soles of feet with blunt object.ii) Telefono : Simultaneous beating of both ears with palms.iii) Quirofana : Beating on abdomen while upper half of body lying unsupported on table.
Forensic Medicine
{ "Correct Answer": "Beating of feet", "Correct Option": "B", "Options": { "A": "Suspension by wrist", "B": "Beating of feet", "C": "Placing electric wires in vagina", "D": "Clamping of thighs between bamboos" }, "Question": "Falanga is -" }
null
ea2b92d7-e16d-4229-9f52-fe6d69487a16
null
Pathology
{ "Correct Answer": "Presence of satellite cysts or daughter cysts", "Correct Option": "C", "Options": { "A": "Increased mitotic activity of the epithelial lining", "B": "Friability of the epithelial lining", "C": "Presence of satellite cysts or daughter cysts", "D": "Continued proliferation of rests of dental lamina" }, "Question": "The most ideal explanation for recurrence of odontogenic keratocyst is" }
null
eef4bc79-54f8-44a9-97a5-47bdc62e9822
Beck Cognitive therapy is a psychotherapy developed by American pyschiatrist Aaron T. Beck. Cognitive therapy is one of the therapeutic approaches within the larger group of cognitive behavioural therapies. Cognitive therapy seeks to help the client overcome difficulties by identifying and changing dysfunctional thinking, behaviour and emotional responses. This involves helping clients develop skills for modifying beliefs, identifying distoed thinkings, relative to others in different ways and changing behaviours. Treatment is based on collaboration between client and therapist and on testing beliefs. Therapy may consist of testing the assumptions which one makes and identifying how some of one's usually unquestioned thoughts are distoed, unrealistic and unhelpful. Once, those thoughts have been challenged, ones feelings about the subject matter of those thoughts are more easily subject to change. Beck initially focussed on depression and developed a list of errors in thought that he proposed could maintain depression, including arbitrary inference, selective abstraction, over generalization and magnification (of negatives) and minimization (of positives). According to Beck's theorey of the etiology of depression, depressed people acquire a negative view of the world in childhood and adolescence. Children and adolescent who suffer from depression acquire this negative view earlier. Depressed people acquire such view through a loss of a parent, rejection by peers, (criticism from teachers or parents, the depressive attitude and other negative events). When the person with such view encounters a situation that resembles the original conditions of the learned view in some way, even remotely, the negative views of the persons are activated. A simple example may illustrate the principle of how cognitive therapy works Having made a mistake at work, a person may believe "I am useless and can't do anything right at work". Strongly believing this then tends to worsen his mood. The problem may be worsened fuher if the individual reacts by avoiding activities and then behaviourally confirming the negative belief to himself. As a result, any adaptive response and fuher constructive consequences become unlikely, which reinforces the original belief of being useless. In therapy, the latter example could be identified as a self fulfilling prophecy or "problem cycle" and the effos of the therapist and client would be directed at working together to change it.
Psychiatry
{ "Correct Answer": "Beck", "Correct Option": "B", "Options": { "A": "Ellis", "B": "Beck", "C": "Godfrey", "D": "Meicheinbanon" }, "Question": "Cognitive model of depression is given by ?" }
Fundamentals in Radiology
e2242b6b-7fb0-4015-a389-66c21827cdcd
MRI as the diagnostic test of choice for hepatic hemangioma at most centers. Nuclear medicine studies may be used to confirm the diagnosis when a probable hemangioma is detected on ultra-sonography. Nuclear medicine studies may also help to clarify the nature of a lesion when the diagnosis is equivocal on CT or MRI. Percutaneous biopsy of a hepatic hemangioma carries an increased risk of hemorrhage. Liver biopsy is contraindicated in most circumstances where a hemangioma is high in the differential diagnosis of a hepatic mass. Hepatic angiography: The diagnostic accuracy of noninvasive tests has obted the need for hepatic aeriography in most cases.
Radiology
{ "Correct Answer": "Hepatic scintigraphy", "Correct Option": "B", "Options": { "A": "Ultrasound guided biopsy of the lesion", "B": "Hepatic scintigraphy", "C": "Hepatic angiography", "D": "Contrast enhanced CT scan of the liver" }, "Question": "A 22 years old man presents with a solitary 2 cm space occupying lesion of mixed echogenecity in the right lobe of the liver on USG. The rest of the liver is normal. Which of the following test should be done next?" }
Fundamentals in Radiology
858c4c56-8d14-48dd-bb95-5195df720725
contrast agents used for myelography are : Iohexol Iopamidol Metrizamide Myodil
Radiology
{ "Correct Answer": "Myodil", "Correct Option": "B", "Options": { "A": "Conray 320", "B": "Myodil", "C": "Dianosil", "D": "Iopaoic acid" }, "Question": "Dye used for myelography" }
Misc.
e3ef3bc0-f3e5-4597-941c-364749ac436d
(C) IL-4 # Pyrogenic cytokines: Known pyrogenic cytokines include IL-1, IL-6, TNF, ciliary neurotropic factor (CNTF), and interferon (INF)a. Others probably exist; although IL-18 - a membrane of the IL-1 family - does not appear to be pyrogenic cytokine. Each cytokine is encoded by a separate gene, and each pyrogenic cytokine has been shown to cause fever in laboratory animals and in humans. When injected into humans, IL-1, IL-6 and TNF produce fever at low doses (10 to 100 ng/kg).> Fever, characterized by an elevation of body temperature, usually by 1deg to 4degC, is one of the most prominent manifestations of the acute-phase response, especially when inflammation is caused by infection. Fever is produced in response to substances called pyrogens that act by stimulating prostaglandin (PG) synthesis in the vascular and perivascular cells of the hypothalamus. Bacterial products, such as lipopolysaccharide (LPS; called exogenous pyrogens), stimulate leukocytes to release cytokines such as IL-1 & TNF (called endogenous pyrogens) that increase the levels of cyclooxygenases that convert AA into prostaglandins. In the hypothalamus the PGs, especially PGE2, stimulate the production of neurotransmitters, which function to reset the temperature set point at a higher level. IL-4 is involved in immediate hypersensitivity reactions.
Pathology
{ "Correct Answer": "IL-4", "Correct Option": "C", "Options": { "A": "IL-1", "B": "TNF-a", "C": "IL-4", "D": "IL-6" }, "Question": "Which is NOT pyrogenic Interleukin" }
Respiration
df63e2e9-3cae-4be2-9699-29e945035e02
Ans. (d) Heart failure cellsThe lung biopsy shows intra-alveolar transudate granular pale pink material along with alveolar micro-hemorrhages & hemosiderin-laden macrophages ("heart failure" cells) seen in left-sided congestive heart failure.
Pathology
{ "Correct Answer": "Heart failure cells", "Correct Option": "D", "Options": { "A": "CMV pneumonitis", "B": "Small cell Ca lung", "C": "Tuberculosis", "D": "Heart failure cells" }, "Question": "A 45-year old male presented with severe respiratory distress. O/E he had pedal edema, bilateral crepitation on auscultation. He was admitted to emergency department and expired 2 days of admission. Lung biopsy done suggested the following. What is your diagnosis?" }
Law & Medicine, Identification, Autopsy & Burn
9d03e175-6ba0-4834-8ce2-1e8bd96adb2f
Ans: (a) Cognizable, non-compoundable and non-bailableRef: The First Schedule, Classification of Offences, Indian Penal CodeCognizable offencesCognizable offences are more serious crimes wherein police can arrest the suspect without any warrant.Ex. rape, murder, ragging, dowry death etc.Compoundable offencesCompoundable offences are those offences where, the complainant (one who has filed the case, i.e., the victim), enter into a compromise and agrees to have the charges dropped against the accused.Bailable offencesBailable offences are less serious crimes wherein the suspect can be released from custody by furnishing a bond on bail.
Forensic Medicine
{ "Correct Answer": "Cognizable, non-compoundable and non-bailable", "Correct Option": "A", "Options": { "A": "Cognizable, non-compoundable and non-bailable", "B": "Cognizable, compoundable and bailable", "C": "Non-cognizable, non-compoundable and non-bailable", "D": "Non-cognizable, compoundable and bailable" }, "Question": "Murder is.............. offence." }
Gynaecological oncology
fd011c29-dc35-41a9-ba97-23ffdcf9a75d
Management of Advanced stage diseaseIncludes stage III and IVDebulking surgery versus neoadjuvant chemotherapy followed by Postoperative chemotherapyPrimary cytoreduction surgery is the preferred in1. Retroperitoneal only disease preoperatively 2. Patients with stage IIIC or IV disease with good performance status who have < 5cm upper abdominal disease 3. Patients who are considered ideal for intraperitoneal chemotherapy if optimally reducedNeoadjuvant chemotherapy and interval debulking surgery is preferred in1. Patients with bulky upper abdominal peritoneal disease >5cm in diameter2. Medically unfit for surgeryPostoperative chemotherapySystemic chemotherapy with 6 cycles of carboplatin and paclitaxelPostoperative radiotherapy1. Not effective compared to chemotherapy2. Used clear cell or mucinous carcinomasMAINTENANCE THERAPY1. No role after the complete clinical response 2. Drugs used: 3month or 12month paclitaxel every 28days
Gynaecology & Obstetrics
{ "Correct Answer": "Debulking surgery", "Correct Option": "A", "Options": { "A": "Debulking surgery", "B": "Mantle cell irradiation", "C": "Abdomino-pelvic radiotherapy", "D": "Neo-adjuvant chemotherapy" }, "Question": "In stage III ovarian cancer patient with upper abdominal disease < 5cm, management of choice is" }