Skeletal formulae of <a href="https://en.wikipedia.org/wiki/clonidine" class="extiw" title="w:clonidine">clonidine</a> and <a href="https://en.wikipedia.org/wiki/lofexidine" class="extiw" title="w:lofexidine">lofexidine</a> — both are <a href="https://en.wikipedia.org/wiki/Alpha-2_adrenergic_receptor" class="extiw" title="w:Alpha-2 adrenergic receptor">α<sub>2</sub> adrenergic receptor</a> agonists. Created with <a rel="nofollow" class="external text" href="http://www.chemdoodle.com">ChemDoodle 7.0.2</a> and <a rel="nofollow" class="external text" href="http://www.adobe.com/products/illustrator.html">Adobe Illustrator CC 2015</a>.
<a href="//commons.wikimedia.org/wiki/User:Vaccinationist" title="User:Vaccinationist">Vaccinationist</a>
Own work  using: <a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/2803">Clonidine on PubChem</a><br><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/30668">Lofexidine on PubChem</a>