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  -                                <%--IMPC images--%>
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  -                                <div class="section" id="vignettes">
  -                                    <h2 class="title">Vignettes </h2>
  -                                    <div class="inner">
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                           <%-- commented out venn diaggram for now as disease classification that it relies on is problematic in phenodigm --%>
                           <%--<div class="section">--%>
  
positive.code:                                 <p>In order to identify the function of genes, the consortium uses a series of
                                      standardised protocols as described in IMPReSS (International Mouse Phenotyping Resource of Standardised Screens).</p>
                                  <p>Hearing capacity is assessed using an <a
                                          href="https://www.mousephenotype.org/impress/protocol/149/7">auditory brain stem
                                      response</a> (ABR) test conducted
                                      at 14 weeks of age. Hearing is assessed at five frequencies – 6kHz, 12kHz, 18kHz, 24kHz and 30kHz –
                                      as well as a broadband click stimulus.  Increased thresholds are indicative of abnormal hearing.
                                      Abnormalities in adult ear morphology are
                                      recorded as part of the “Combined SHIRPA and Dysmorphology” protocol and in the developing embryo during gross pathology examination.
                                      Full procedures details are provided in the list below.
                                  </p>
                                  </p>
  
negative.code:                             <%--deafness manuscript --%>
                              <h2 class="title">IMPC Deafness Manuscript</h2>
                              <div class="inner">
                                 <h3>IMPC data reveals a large and unexplored genetic landscape involved in auditory function</h3>
                                 <ul>
  	                               <li>
  	                               Around 360 million people worldwide live with mild to profound hearing loss, of which approximately half have a genetic basis 
  	                               </li>
  	                               <li>
  	                               The extent of the mammalian gene set that impacts auditory function is unknown
  	                               </li>
                                 </ul>
                                	<ul class="pad10px">
  		                                <li>Press releases: <a href="https://www.mousephenotype.org/news/study-unprecedented-size-reveals-how-sex-%E2%80%98blindspot%E2%80%99-could-misdirect-medical-research">IMPC</a>&nbsp;|&nbsp;<a href="http://www.ebi.ac.uk/about/news/press-releases/sexual-dimorphism-dilemma">EMBL-EBI</a>&nbsp;|&nbsp;<a href="http://www.sanger.ac.uk/news/view/study-reveals-how-sex-blindspot-could-misdirect-medical-research">Sanger</a></li>
  		                                <li><a href="http://em.rdcu.be/wf/click?upn=KP7O1RED-2BlD0F9LDqGVeSJ-2BYK13AOQwsehfu7fiqrAw-3D_rlS5NjXTpmOl66SHsP12rLQI7Hycd1QZjA7AhdQ2b6-2FS-2FPWAuljWGaoUUyQdBhNd5qzu1OSDRnDXa0UviCH1ywsoXX2HEGPW67FIlbNWZVB87NAsEeYQQ3F2GD8bvwBOk-2BPkbKRPqfrgHP4barsF-2BrLfjDnMD0fmPe675sK7phkS3L5CVy1mUUmp4mw-2Fgzbv1ueMSvy-2FUyo41KChqsXtnXKcvriwPUvjZxg6BOMnIFU-3D">Manuscript</a></li>
  		                                <li> <a href="https://zenodo.org/record/260398#.WVIkChPys-c">Supporting material to enable replicable analysis</a></li>
  		                        </ul>
                                 	<h3>Hearing loss investigated in 3,006 knockout mouse lines
                                 	</h3>
                                 	<ul>
                                 	<li>
                                 		67 genes identified as candidate hearing loss genes
                                 	</li>
                                 	<li>
                                 		52 genes are not previously associated with hearing loss and encompass a wide range of functions from structural proteins to transcription factors                               	
                                 	</li>
                                 	<li>
                                 		Among the novel candidate genes, Atp2b1 is expressed in the inner ear and Sema3f plays a role in sensory hair cell innervation in the cochlea
                                 	</li>
                                 	<li>
                                 		The IMPC has currently explored 15% of the mouse genome suggesting a minimum of 450 genes required for hearing function in the mammalian genome
                                 	
                                 	</li>
                                 	<li>
                                 		The IMPC will continue screening for hearing loss mutants in its second 5 year phase
                                 		
                                 	</li>
                                 	</ul>
                                 	
                                 	<h3>
                                 		Approach
                                 	</h3>
                                 		Response data from the auditory brainstem response (ABR) test was used – hearing at five frequencies, 6kHz, 12kHz, 18kHz, 24kHz and 30kHz, was measured.
  								<ul>
  								<li>
  									Control wildtype mice from each phenotypic centre included, matched for gender, age, phenotypic pipeline and metadata (e.g. instrument)
  								</li>
  								<li>
  									Our production statistical approach that automatically detects mutants with abnormal hearing was manually curated to yield 67 genes with profound hearing loss
  								</li>
  								</ul>
                           
                              </div>
                          </div>
                          
                          <div class="section">
                              <h2 class="title" id="vignettes">Vignettes</h2>
                              <div class="inner">
                                  <p>[Vignettes here, in addition, or instead of, some figures in the Publication section]</p>
                                  <p>Coming soon.....</p>
                                  
                              </div>
                          </div>
                          
  
                          <div class="section">
                              <h2 class="title" id="phenotypes-distribution">Phenotypes distribution</h2>
  