InnoDB buffer. Should I increase buffer size? Database monitor



InnoDB and Key always 100%. How can I increase buffer size ? 
can this cause any problems or slow database speed?  

My configuration

skip-external-locking
key_buffer_size = 64M
max_allowed_packet = 32M
table_open_cache = 256
sort_buffer_size = 4M
read_buffer_size = M
read_rnd_buffer_size = 10M
myisam_sort_buffer_size = 64M
thread_cache_size = 16
query_cache_size= 64M
thread_concurrency = 16

#innodb_use_native_aio = 0
innodb_file_per_table
Short answer:  Set innodb_buffer_pool_size to 70% of available RAM (assuming you have more than 4GB of RAM).

Long answer:  For deeper investigation, we would need SHOW VARIABLES, SHOW GLOBAL STATUS and the RAM size.  And the buffer being "full" does not mean that things are running poorly -- it is a cache.