Feature SQL Server 2012 - Filetable - The location of the file can not be opened When trying to access the files available on the virtual directory created for FileTable, you receive the following error message:


  "The location of the file can not be opened. Access is not enabled or not you have the permissions for it."


Already granted all permissions, however, the application displays this error.
You need to have 


  "Allow remote clients access to FILESTREAM data"  selected  as shown below :




Also, you need to leave the windows share as a Globalroot path and manage permissions through table properties, not Windows share properties.

Refer to : Prerequisites for FileTable