Full Transaction Log on closed source system I have a closed source application which has the transaction log filling up on a daily basis to 60+gigs. 

I have ran a trace on the database and no inserts and updates are occurring. The following statement though is being executed THOUSANDS of times per minute which doesn't seem right.

set transaction isolation level read uncommitted


If this is not the cause of the issue, is there anything else I can do to find the cause of this issue without turning off full backups as its required.

Thanks
You can try to use some third party tools for transaction log reading, ApexSQL, Idera, RedGate. You can also try to determinate by using fn_dblog function, with all that executions you should be able to easily see the problematic statement:

SELECT [Current LSN], Operation, Context, [Transaction ID], [Begin time] FROM sys.fn_dblog (NULL, NULL)