The luminence of pixels on a computer screen is not usually linearly related to the digital RGB triplet values of a pixel. The nonlinear response of early CRTs required a compensating nonlinear encoding and we continue to use such encodings today.

Usually we produce images on a computer screen and consume them there as well, so it all works fine. But when we antialias, the nonlinearity — called gamma — means that we can't just add an alpha value of 0.5 to a 50% covered pixel and expect it to look right. An alpha value of 0.5 is only 0.5^2.2=22% as bright as an alpha of 1.0 with a typical gamma of 2.2. 

Is there any widely established best practice for antialiasing gamma compensation? Do you have a pet method you use from day to day? Has anyone seen any studies of the results and human perceptions of the quality of the graphic output with different techniques?

I've thought of doing standard X^(1/2.2) compensation but that is pretty computationally intense. Maybe I can make it faster with a 256 entry lookup table, though.