**If I place runes in the sockets of Wirt's Leg, can I still use it to get to the secret cow level? Or does it have to be "clean" for that to work?**

Reason I am asking is because it is the only weapon that I have with 3 empty sockets, and I have (luckily!) 3 Tal Runes. These do +75 poison damage over 5 seconds. So I would get a minimum 225 poison damage before my other perks kick in.