We are getting the error like this

```
12/06/2015 14:42:35   HTTP JVM: CLFAD0211E: Exception thrown. For more detailed information, please consult error-log-0.xml located in F:/Lotus/Domino/data/domino/workspace/logs

12/06/2015 14:42:35   HTTP JVM: CLFAD0246E: Exception occurred servicing request for: /xsp/.ibmxspres/domino/ckeditor/ckeditor.js - HTTP Code: 500. For more detailed information, please consult error-log-0.xml located in F:/Lotus/Domino/data/domino/workspace/logs

12/06/2015 14:42:36   HTTP JVM: CLFAD0211E: Exception thrown. For more detailed information, please consult error-log-0.xml located in F:/Lotus/Domino/data/domino/workspace/logs

12/06/2015 14:42:36   HTTP JVM: CLFAD0246E: Exception occurred servicing request for: /xsp/.ibmxspres/domino/ckeditor/skins/lotus21/editor.css - HTTP Code: 500. For more detailed information, please consult error-log-0.xml located in F:/Lotus/Domino/data/domino/workspace/logs

```

or 

```
12/06/2015 16:22:37   HTTP JVM: CLFAD0211E: Exception thrown. For more detailed information, please consult error-log-0.xml located in F:/Lotus/Domino/data/domino/workspace/logs

12/06/2015 16:22:37   HTTP JVM: CLFAD0246E: Exception occurred servicing request for: /ASAP/helpdesk2000.nsf/xpASAPRequest.xsp - HTTP Code: 500. For more detailed information, please consult error-log-0.xml located in F:/Lotus/Domino/data/domino/workspace/logs

12/06/2015 16:22:38   HTTP Web Server: Command Not Handled Exception [/path/db.nsf/xpage.xsp?documentId=BE7D455563ECAD9DC1257E5F0031A703&action=editDocument&viewname=abc&$$ajaxid=view%3A_id1%3AidAssignTo] CN=user name/OU=OrgUnit../OU=OrgUnit../OU=OrgUnit../O=Org..

```

This does not happen always but happens 6 to 8 times every day.
Please help to identify the reason and how to rectify.