Looking for hints and tips on speeding up and streamlining performance of a Craft site as we prepare for launch. 

The database is approaching 100MB and whilst it is a fairly large and complex build (multiple locales with fairly extensive use of Matrix) this seems fairly excesive and page load times can be slow. Have looked at the Patrick Pohler post but any general, system level wins would be great as site is crawling a fair bit.

Am getting some performance increase through use of {% cache %} tags but then hitting DeleteStaleTemplateCaches issue qiute regularly which is stopping tasks running.

Any help appreciated!