For most of the macroscopic observations, everything has a reason, but going into the microscopic level, atoms, then the electrons, then quarks.

Science has proved the existence of quarks by various experiments, but no one has ever seen them, though, electron filming has been done but it is blurry.
Who knows that the thing we are assuming to be present today may not what it seems to be?

How can one conclude that conclusions of scientific experimental results (hypothesis) may always be correct?