Is there a check by which a combatant can force-feed an unwilling target a potion? 

The question stems from several magic items, including the Potion of Diminution and Potion of Poison. I am seeking to develop an expanded list of potions for the Unearthed Arcana Artificer class and the ability to affect an enemy with potions such as these would be grounds for a much higher spell slot to Infuse than if it was restricted to willing targets (or misled, in the case of Poison). 

This question is specifically in reference to conscious opponents, enemies who can resist the attempt.