Datasets:

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[ "vienal Eoemate euch se ciek Madders” [36), populstion\ncharts [27], ple charts [28], and histograms [29-31] sug\njest better understanding, increased isk perception,\nhigher sk aversion, and better aeceplance of interven\nons in pallens. Restrictions on the use of visual fr\nwots dani iaok bn Became Uepslsine os ue lio", "Ara FR ESN br HE COARSER eae Senem Peo Ee. BE\nature, which show that visual lormats are easier\nunderstand than ther, especially verbal, formats [5-7\nOnly few studies address the visual formats used by\nhe physicians in our study [25] However, compared t\nTeil all pained Sectieds aloe, Recigs or athe", "", "", "" ]

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[ "(for decidua: 10mg/ml, PA, 37°C; for endometruum: 0.6mg/m.,\n12h, room temperature). The srpersan war psd hugh\nrcs of ll sine 040m, a layered ont Lmpbonrep\nsine immedi, reared for up to seen dys in RPM\ntions Al vere maples were double stained for CDSE ad\n-U9 (Fig. 1) and thove with any CDS6°CD9 cells prs\nficarded a this indzates contamination by maternal od\nhaces (4). Deda roma cell were separated rom he\nshar and clued a deve (SI. Immature (age 3\nSour calls wore extracted ana catnared an dosesthed [23]", "ee ee ake a, A\nnepndetkeratin 7 (Dao), which war detected inact\nsty wing FOC & PERM {ADG}” CD12? (ebiscince)s NEP\n(RAD). NKGZA (ope 7198, Bec Cote) COIS! (BD),\nLAC (DTS Kind pit of Veronique Brau) ap HLA (doa\nSDI, eisciene) exprnion was examined by inc sain\ninary ssboy (mi, 4), then Wael nd ited it\nati mau (Sigma) Cn, 4) olwing a father wh,\nls were locke ip O.mg/ni. mow 7 globulins (Sem\n‘smin 40) and stained wah deetlyconugted anol 3\nW000 events calla theengh the gate of interes.", "ee ee eee\nsmn, 4C) blk non spec nding ear neaton wa\nnsrocrone cnjpsted snd (30min, 4). Diet con\ntel anodes were: CDS6, KIEZDLI/S1 clone 6, LR\none HPEEI (Beckman Cole); CD9, COS felone 151412,\nraneiaAb/es Gun Coke. Cons. Com Coes crea", "1819}. ee, he individual genes were enotyped by PC fr\nso Fis of primers per gene orale KR pene ped wer", "", "Patient Cycleday Cycle length Serum progesterone (ng/ml) Phase assigned Antigens examined\n2 8 n ese Seaetory EDS, CDE, CDSG, NKpA4, Np", "riow cytometry", "Genotyping of KIX and HLA-C" ]

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[ "or sghes apes. er pect needed Et = que dad\nhis ls towards diferent organs. Compound (benz) a\ndn (CHsNMe bene) esitaned broad-spectrum activity bat\nCHR-Etsaangl) vand Lanetiva aguinet a hiseheion at'25 pt", "tee microorganisms at the highest concentraden tested. These\nehued the now aromatic tomorpholne aide 4, amine\nto the carbonic cds rand aa\" me hye 9a\nyyy ap were inactive against E saya and lm\nnd wealy patent against Cai, comin the tend\nae te ae el eon", "OO ee aieate that me parent ane © possesses panent\ntivity against Cite, E hiss abd G lable. THeefore\nvive assessing combat ike Has of ee mater fo\nological acti the ai of ay teat pate compoud\n=a part consideration, pat wes te inp", "The MICs of 1. 3 and 4a-t were >32 ug/ml against the repre-\nenfative ESKAPE pathogens (MRSA, Ecol pheumonie\nation, he MC values subset of compounds (netoniazo\nazide 4a (pen) a (CO) eral 4 pn aga\npatel af additonal og festa S ares ssi vcore\ncosta Jaca, anconyein estan Jct abd mule\nseta Spe Ts ack of atv conta to Been\nport. bat consistent wih the repertedlaactly of 378 Mt\nroles agaist Ecol in Miyrot's st and the inet\nmatrenidatola apuinet facuteseive aniarabie hecuta,", "eaters Cane tte ttetinii.\nth epidemies (Table 1), The MICS of individual eompouts typ\naie ested Tus sport. as abled eanddates st\npossess appropriate broad aan coverage A evew of ania\nng candites in development found that att) against mls\nple strains of eifite culd vay substan [20 Ths ca be\npained since Cafe as 4 highly mole ase genone\nneces wie tain diversity between Solas [2122 lates ea\npe vied arose min pylogenetic lage, mule rate\nnd toxnypes [25 Recent genomic epidemiology sta\nining apd aching C fic outbreaks i Turope foun ha\nigh propo of sans causing lection were no ated\npio infectious stains (22. Teteloxe, there a ge pol\ngenctcaly diverse stuns fo the conway and seecon an\npend of nes sessan stains could eect However. th\ndan atvy ef Ma-tiaznes agit Caf ths\nssecacane Sethie demaiegwasat of tae thaws", "SS ee ee es ee\ncviaat tants ping of C ie incites tom call", "Mans mepiepeieanie upelstnace bas been aepanied is the clae\n9.24, perlorming antimicrobial suscepbiity testing aginst\nestan! Cf iolates i peoblematie since the resistance\nphenotype usable and often reported to beloston ene ha\neles oon passing the sates [5 However eet a ae\nported stable metronidaole resistant (MU) ail don\n5, The actly af Mtoe was sessed gant ti a\n2 Stain fC bf (CDZEASA.R) andthe patent tron\nae senstve (Mes) (CD26ASK S) tain which asthe meta\nle weston ee hig bt ete 4 gy\nSara eer cared Cie Ma 4a egheoeddla in nd cme", "McEWvily GF MI2-SreazOles agaiiist ¢. dayicie EAE Decora, & Nisei dake to lovin.", "cree peed in ng coment seen win 3 Ee, whe he 3ICE aM DRRNTEE ESMONATCE ae", "", "ped eee", "RA ACUICY of metronichzote niazale Conpegates against\nsclvenhinads reshetest Ee aude", "" ]

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[ "ae StaDIEY (Oe Broce catise’ Oy mutation, maratona’ using\nisan 30 [2] i ras where ele pe tation\nseveral honk seas Testud the ee of ation\ner the say nd might led to pabogeicty ae peas\nported flyPhen2(Plenorpis Pheotyping v2) [25] 3 oa\nwh predispose pct ofan ain cd sbststton oh\ntrsctre at function of human proteins that deseie the hn\nynoayenus Pec Ths to analyte elles a mation th\nol has Bee sed encoe the damaging elect determined by\nseasttuthy and sparttichy scnma", "ee ee ae\nexecpt the sic laa apes ol seer proteins. The sat\nseaperinental methodlogis hs ben singed by siulato\npprch as revel the chan inlved in alos el\nhe prot, Herein ou stay the elec dais silat\nporch hasbeen applied to ty the say aspect a Wl\na uted pees In ard pepie 1-12 Fr he pose\ndeity the fects fata the tated id wd type pts\nwere subjected to Seale Malet Dyas NAMD [24 sta\nom Theoret Bop Group, Unive a lina pd ena\nsti which command ine progam inept nd esd\need tiecvior aaa tin reine", "he pathogenesis of AD is a hypothesis, which ls supported by\nete evidence at argues te accumulation and apse\nyd fee Several mistnse uaa support fet hl\nhe change ithe ana ace eas to onat of AD. The pray\nclr faye precise poten mutation ave been pre\nur snc tm 1290, sao fer the destin ef pao fA\nby German psi and ea pathalogt As seme i 80\n2] The common type af mutations ate Swedish (1982) Feri\n1962), Dtch (1990), Act (2001), ian (2010), Oka (2008\nJn 001, Astin (200), aa (2002) Fen 198), Ce\n200) led (1997), endo (1981) dian (190), an Atala\n2000 Experimental evidence by NMR studesWenied tat\natts at poston £22 and 023 mains destalize th un\nregion V4 to Ks (ig) hey promt igor fea\nat cendts ta agavegetion 130311", "_ The ammytid Struchire aggregation prediction that & a resubass olf\nets om het stbiaed residues second strc conor\non waste as epi inthis work whi was doe by Si\nPASTA 20. The egal lls generated ths ply ta the resides\nging fom 32 fo 40 sued to alan eet conformation\namy cegions The grap states the pra agpezao\nbei esi ange of 12-40. great ee ebery Poi\nsar pote precited fom the ster sows tha theres\nong to the rsa fange 320 fo oration of ase\nvere slow te tveold sue, which lay shows the tay\ndet and aggyegation of ame saplene an chem ta (ig abc)", "were cone using several Parameters, The temperature was set ta\nSOK with CHARBEM oc eld are and tgiate tie tp\n2 The pele was cantered wt ube sion bat wt\nam dslance alowed between the peptide ad the edges a the\netd wh peer candns where tsb the Stab\nsta prt nde aso bat whch the dean nthe BSD a\npapal LANGEVIN Temperature ha ideal parameter\niiguation fe and PME Cor flystem pero cna)\nwere slo 175 ding parameterization The estat enc Wa\ntw S00 see for ety 1 pe The sation and Gti wa\ndone for 10 ps wih 4 fae ate af 1100 that plots + devise\nVSD} in whch the stay ofthe pons was yz se show\naa", "Scere Ana naptianierieeerienrenl: don oneehaeiapechmrieeren\nconformations de to mutations in protein tough MD simulation\nch dpi theatre molec apt i atoll Te\nted proteins wel the wpe een were sujet to VD\not pce Sects generation PS), which s precast\nNALaD sianaetion, Tha sueheization ueel ayitcarin’ of the peottias", "eee", "~ é\n: cs\ncs", "", "3.3. Types of mutations", "", "+. Dynamics", "" ]

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[ "nue to people exerting more pressure on the already\nweak health system as they fled the conflict zone. The\nmmpact ofthis station on the 6 bulding blocs ofthe\nWHO in tems of diabetes inthe two ates of Mal\nstamarized in Table 1. Becaise of this people with\ndiabetes faced a whole sees of challenges in terms of\nsocom [toes ead caoiciaoe (LI", "As of Apel 2012 4 manesive hemmeniiecion reqpones wes\naganized to help the 224 rallon people living in ae\nlec impacted by the conflict and 198.500 displaced\npeople (190. To addrets this situation two parallel\nsponses were developed, ne by the Ministry of Health\nechnical aff andthe other developed by humanitarian\ncrs. Both of these were then combined ino a Com\nmon Humaniuisan Action Plan. The overll resources\nlocated to this cists were USS 150 milion for the\neral humanitarian response and USS 95 millon\nspecifically for health {19,20},", "tuicren’s Fund (ONCE) Gecined’ to support diabetes\nlated activites deste the small amount quested, USS\n11000 ftom OCHA and USS 12.700 from UNICEF. The\nesponse fom OCHA was “betes ig notin the fame\nwork and nots emergency” and UNICEF stated “Dishes\nno a ploy” [21 It was not the actual proposals de\noped by Sant Diabite that were eeted, but the pop\nton in eel need of labetes services ot seen a\nroety by thse responding tothe ers. The reason fo\nhs that people with NCDs and diabetes were ot in\nded in thepriety Ist’ as Uy were not considered a\nrulerabe. Diabetes shouldbe seen a a platy as peopl\nwth this condition are vulnerable even in norte cu\nsauces a eet Leleip oneeeshched aren a pekea we celia", "Jin asking for support for people with diabetes Sante\nDisbite received many negative reqponse froma tndiina\nJonas. Far example the Oifice for the Cootdatin\nof Humanttarlan Affairs (OCHA) and United Nations", "ae cn Oe ee rr ency Srategy\nor people with dabetes building off is knowledge and\nexperience asa development NGO ative in Mall since\nSu Tics eet ocened os nw toot partie", "Table 1 Impact of conflict on the health system in the north and south of Mali [18]", "WHO Health System Building Block Ee ven a\nety Tine es BERET deo ry\n‘Somanter mena Seed ppl\n\nny 2 fase Lined af een\n{See poe ces\n\nten ee ‘am core at a an anne\ncUeieume Novatel Sa em aaa ey\n=e Rgoncige\n\n— tte ie Lato pyc ela dn\nuae SRS ny ae ae\n\nYe posacenccpet Compe ematinct ies Laclede\n+ Destruction of existing rfasractre wrth chabetessready being managed\n\na fle son onsen rnd ye\ntie pees thee poplin fe sah ed\nslits see’ de dhe ne", "EE\nsti that sea\n1 Inleenatiy nepiaced pomsle we haus" ]

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[ "af both shop types sald a schedule H medicine, although\nchains did not sell any of the move vesticted HI drs\nSeven independent shops (3%) sold HI medicines (all\nof which were antibiotics). I notable that nota sngle\nhop sold fistine antiTB medicine. Figure 2 shows of\nmedicine sales, the proportion accounted for by each\nmedicine category. The reals are suikingly similar for\nchains and independents, Almont two-thirds cf enedicnes\nold were cold and/or cough preparations. The second\nand third mos commonly sold medicines were anti\n“ici cud enlentbonn dicta, seapectioaly", "are comeiciered Rareninl in (he manegument of (his case,\ntd chains were found to sell significantly fewer of this\ncombined category of harmful medicines (35% vs 48%\n\np-0.029). Antibiotics” or antidarrhoeals accounted for\nreay all the schedule H medicines sod thus, we see\ngaifcandy fewer chains selling schedule H medicines\n(39% v8 40%, pa0.045). H1 category medicine was sold\npy one independent pharmacy and no chain A quarter\nof chain and 22% of independent sold eaten that\nae not recommended for darthoea, Although not-bac\n\nrial dirthoea can be managed in the pharmacy, 41%\nof chains and 97% of independents referred the child to\nharem", "‘No sop: managed the cose of childhood dinarhoen\naccording to current guidelines (Figure $ and online\nupplementary appendix A2 for corresponding table).\n\nFurther, no shops sold oral relation sls (ORS)\nand zine together. The sale of zine was extremely sate,\nrecommended by only two chain shops (2%) and no\nindependents (p=0.084). Only 125 of chains and 10%\nof inwependents sold ORT and in exactly hall of these\nales: this was alongside harmful medicines A total of\n29% of chains and 42% of independents sl antbitis\n\nAntidiatshoeal use was also higher in independents, 7%\n5 9 ter casi, ots autaes acid cece", "(OF medicines acid She the patient with dlerhoes,\nworryingly, antibiotics made up the largest proportion\nor both chains and independents, 45% and 52%, respec\nively (gure 4). Prebioucs and probiotics were popula\nccnmien Ser SUL of as a choles ond Se So", "", "Table 3 History taking in chain and independent pharmacies when presented with cases of suspected TB and diarrhoea", "", "Canin pt Independent (n=230)\n\ncase Recommended questions _% (95%cI) sesh pValue\n\n‘Suspected TB Consulted a doctor? 19 @sw75 S5(7io8m) os\n(Chest pain? 1001310087 25 (121057) 0536\n‘Sputum or biood in cough? 11.7 (67 to 105) 135950185 08t6\nWeaknes orfaigue? 0.9(02t034) 0302\nWiig oss? ° °\nLoss of appetite? ° °\nconten ° °\nNight sweats? 1001 100-7) 17071048) soe\n‘Any oter symptoms? ——-4.9,20%0112) 170748) 0s:\n“Wed any medicaton? 0 17071048) x78\n‘Asked any recommended 16.8 (105 1025.0) 226 (17710285) 0.208\nquestions?\n\nDiarnoss ood in stool? ° °\nDurston ot demos? ——3.9(1.5t0 100) 44p4t079) oss\nNumber of stools per day? 49 (2010 1.2) 22(090%05.1) 185\nNumberof episodes ot 1.9(05t07.5) sapot07) oss2\nvomiteg?\nPrasance of ever? ° 09,0210.) 0302\nProline focding practices? 0 °\n“ype of fulds and toods 0 ©\nung arass?\n(hia passing wine? ° o4portoss) 50s\n“Wed any medicaton? °\n‘Asked any recommended 9.7(6.310172) 21 (6010136) ose?\nquestions?" ]

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[ "ee eee\nound. when adjusting for age, gender and number o\nvoxels in the SCP: (i) FA. was associated with th\ninverse of TWT (bein ~0.0012, 98% CI 0.002,\n0001, p=0.047} (i) MD was associated with th\ninverse of TWT (hela O40, 95% CL 0.035, 0.7\n)=0.035); (i) RD was associated with the inverse o\nWT (beta 05, 95% CI O12, O88, p=0016\nFigure 3) (0) FA was associated with the inverse o\nHPT (beta 0.15, 95% Cl -0.28, -Q011, p=0039)\nFigure 3). No. other associations were observed\nbetween the tractography-derived measures of th\nMCP or SCP, of cerebellar GM volume, and perfor.\nance on te clinical ests. In particular no association\nvas found between MRI mcasures of erebelle dame\nnd CESS.", "Vorrecting tor age, gender and’ the number of Tract\nyotls, there was no signiiant association of nonma:\nzed cerebellar GM volumes with tractography deriv\nvalues of the MCP and SCP in patients with cites\nnceenclpeny", "TE a ee eee\nRMS; (i) cerebellar WM volume was associated\nvith worse performance on the upper limb moto\nask in patonts with PPMS; (i) in patients with\nPPMS, there were signifeant associations between\nSCP FA and upper limb Function, and between SCP\nFA and MD and walking ability. This latter elation\nhip was mainly driven by SCP radial diffusivity. We\nso explored the association between WM and GM\nJamage in the cerebellum, and found that the exten\nof damage in the WM was independent front that i\nhe GM in both groups of patients. We wil discs\nthese findings in turn.", "me nave Pertormed’ a comprehensive assessment oF cer-\nella involvement in MS using difusion tractography\nand volumetric analsis, and investigated its impact on\nlisabiiy. Our main findings were: () patients with\nPPMS showed reduced FA. which was mainly dive\nwy increased radial diffusivity. in the MCP when", "Ur medng of reduced © in the Nt 1h patients\nvith PPMS extends the results of previous studs\nwhich have reported a. widespread decrease in FA\nsross the hen,\" by showing thatthe mai cerebel\na connections, which contribute to associative, limbic\nens0r9 and motor cites, are affeted.”” Therefor\nlifusion-based tractography is uble to reflect underly.\nng pathological changes and may complemeat, th\nformation obtained with voxe-hased analyse,\" In\nsddition, our analysis suggests that the detected\ndecrease in FA was due to an increase i radia dit\nvty which, despite reflccting the water difeion pe\npendula to the main direction of res, and therefor\nping a marker of demycinaion in animal studies,\" is\nnot considered to Selectively measure demyelination in\nvatient studies.”", "SUIPIESINg'Y, We Cid’ not detect signilicant Clierences\nany MRI-derived measure Between patients with\nRRMS and controls. This could indicate that patholo\ncal changes in the cerebellar tract in thi group a\nTebttlo wad bulow the eonaltivity of the teclalaee. oc", "ee etary a Laer be Coadanes ude unto nnt iste Gah ohn MAD LhLT ILL bs Bante Bea\nmrese of TWT and 9-HPT. pases with primary progesine muepe scrosa, HPT, NveHole Pe Tex: FA, raconal", "x Rm", "nesccation Detween Craue Camoge a up\ncerebellar GM and WM", "Jiscussion" ]

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[ "Open shortage separsents a criicel problem In trnae\nplantation medicine, In 2010, 1192 liver transplantations\nwere performed in Germany as opposed to 1846 net en\nies a the wailing Ist (German Organ Teansplntation\nFoundation (Deutsche Suftung Organtansplntation,\nDSO}, Annual Report, 2010). As a consequence ofthis\nliscrepancy, there is a noticeable trend towards the\nlization of extended donor citer (EDC) grafts. Dat\npovided bythe Eurotransplant International Foundation\ndate that the proprtan of Wer grafts exiting one\nne more EDC inctesed from 29% in 1997 to 73% in\n2010 (Axel Rahinel, Medial Digecto, Eurotansplant\npersonal communication). The proportion af gas wit\nwo or tore EDC increased from 4% up to 28% over the\nsame time period.", "Sven gralts [ED D2). Besides poor gralt quality, the recip-\nats health satus (model for end-stage Iner disease\n(MELD) score) may also influence the outcome alte\nWer transplantation [15], The combination of extended\nciter donors and poor recipient condition may be\nsponsible for a reduction of graft survival fllowing\nWer traneplantation. In 201, the S-year graft survival\nte in Germany was 52.6% compared to the inter\nnational mean of 66.2% (ala provided by DSO, Collab\nsrative Transplant Study (CTS)).", "[Ischemia reperfusion injury (IRI) is a complex inflam-\natory,allogenindependent process commonly sen\nallowing graf transplantation: however, ts prtcaly\npronounced sn marginal organs [13], and may conte\neto poor graft function and reduced survival in thes\neipients [45] During ischemia and. reperusion,\nproinflammatory eytokines such as IL-6 or TNF-a ae\nleased into the sjstemie cecuation by Kuplfer ells\nind migrating aewrophs 6) These molecules induce a\ncomplex inflammatory cascade and trigger the genet\nlon of reactive oxygen specie (ROS) thereby allecting\nhe redox status of the cell 7] I ten, increased na\nnllular levels of oxidized glutathione contibute to\nvpuement of the livers anlloxidtive defense system\ni In addition to sinusoidal congestion caused by\ndthelil sticking of migrating neutrophils an inal\nance between vasoconsecuve (endothelin) [9] and\nasodlatatory substances (NO) [10] may direey dis\nurb the hepatie micecreulation. This considered t\npe a central pathomechanism for organ djfuncton\nsad primary nonfunction [9,10], especially i. marginal", "Therefore, strategies miwt be developed ba improve the\nuncion and survival of EDC organs Several experiment\ndele have shown that tacrolimus precondoning be\njor ver tansplantation has protelive eflets (Table 1)\nThe authors have recently demonstzatel that an ex\nacrolins ish reduces IRL in model of experimental\ner transplantation in eats (14). Based on these expec\nmental findings, a study protocal ofa single ex vivo ta\nvolimus rinse prior to Feperusion in marginal Iver\nvas developed (Teal register EudeaCT number: 2010\n)21539-31, Clinical ralsgov Mente: NCT 01562095)\nThe aim ofthe TOP Study (tacrolimus organ perfusion)\n2 edice hepatic IRI and improve long-term organ\nversie idan tag tnpsanlanistion of anomianl mean.", "The hypothesis of the study is that 9 single an vine te-\nrole perfusion prior to reperfusion reduces IRI and\nimproves longterm grat aural, The primary end\n\npoint isthe maximus alanine tansrainase (ALT) level\nwithin the Crs 48 hours fllowing liver transplantation,\nSecondary endpolats are ALT and aspartate transi\n\n0 (AST) levels, graft function (peathrombin time, bi\n\nubia), and erelinine on days 1,2, 4 and7- In addition,\nhe study documents graft and patient sural, histo\n\njgically confirmed rejection, as well as ichemle-type\nbiliary lesions (ITBL}.", "Table 1 Tacrolimus and ischemia reperfusion injury experimental animal studies", "", "SS SS\nSee PA Was sna Tat Sen —Salanranaaieoms a\nrota 9511 Warn rues at Sie Menciodon anions;\nenrol 8411 Cal omnes Rat Spee Upspemetiten aninciafeses <0\nSecreta 90718 Warn tres Bat Sie santa «eo\nfoGofaineamrctasecie,\nevo nar\ndace. 2008 (11 Wars Sree at Sse semaines neaophltuten <0\nsere 2000) alk orice fat Spe rates ny x\nratchet 2012 144d 2Mtows fat Orgindrae—_—_prinarareecnes ghtathore metal. <O08", "introduction", "Hypothesis and endpoints" ]

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[ 1, 1, 1, 1, 1, 1, 1, 4, 2, 2 ]

[ "a a\npandgap energy value forthe nickel oxide iin the cane\nof 24-38 eV. This suggests hat the optical transition i\nNiO takes place through dec intertnd tastion [19\nAso, NiO can act 8a promoter fo the generation of OH\nradicals {20},", "See ee a ee 2 es eee\nnce they are tn realltrant, and suspected carcinogen\nand mutagen to lving chlrophenols (Cs) posing serious\ncola problems [21], Environmental ites with thes\ncemieals coeur Got indo wastewater, such t pt\nleur refining, and production of pesticides, ait pls\ni, resin, texte on, sohent pharmaceutics and wood\nreserving chemi [22-25]. &chlorphenal (1-CP) has\ntracted interests owing tos direct elevance to environ\nment and informative photochemical behaviors [27].", "Dilirent ADEs remncwing planciic compounds haw\npen reported, suchas UV/H.O, (28), UVieatalyst [29],\nphoto-enton process [0], MWINO [31], UVIH,O¥\nTO; [32.33], 0,/2n0 [34] and UVIO4/TIO, [12] Des\nite extensive research, robust and economic eaten\nnf the 4CP has sl to be implemented, and there I 3\ncontinued need to develop eflecive systems. The majo\njective of this atidy was to examine the effciency of\nUVIH,O,/NIO system. The effets of pH, conceatration\nnf H,0, and the amouat of NiO photocatalyst, on CP\nemia tate were des caheuied,", "CS (purity 99%) and hydrogen peroxkle (20%, wiv)\nagents were purchased from Merck Co. Nike oxide\nnano posider (O8.8% purty and <50 nm parle sie)\nwae obtained om Sigma-Aldrich. Other chemical\nwere of analytical grade and were used without further\npunfeaton. Deionized and doubly distilled witer was\nied throughout this study. The pH of solution was\nsdjusted using NaOH and H,SO,, where needed.", "whe Photocatalytic experiments were perlonmed in a\npatch reactor. The schematic experimental deals of re\nstor are shown in Figure 1 Ie consisted ofa ends\nass eeator (2 L total volume with an inner dlamete\nibd eight of 1 em and 16 em, respectively In each ex\nperiment the reactor was led with 1000 maf a8 aque\npus solution of 4CP- with predetenmined pH. value\nradation was achieved by using UV lamp of 150 W\nediu-pessure lamp) wth main emision wavelength\n10247 rm The UV lamp as located verily i the cen\ner of reactor within a double-wall cooling ester, The re\nction chamber was filed with the enature, which wa\nscared Ibeteteen the mcetiee wl nt UY laces meson,", "EE Se eee ae TO ee Se\nng constant concentration of 100 mg/L 4-CP to simu\nate a high loaded industrial wastewater. The reaction\nwas performed at neutral pH except for afew euns to\nalate pH elfects on the reaction fate For euns of UV)\nH,0;1NiO stems the pH value of solution was adjusted\n3 the desired value before start-up, and then a given\ntnount of NiO was added. The nanocstalyst was mixed\nery well with 4-CP before the sition of given volume\nnf hydrogen peroxide The tine at which UV’ lamp was\nurned an was considered te zero, The inital concen\nrations of HO, and NiO varied inthe range of 0005.\n14 mal/L and 0025-02 g/L. respectivety.", "eee eee Heaee ere ae ene Pet See reac\npredetermined time interials. Potential reactions wi\nhydrogn peroxide and hydrosy ada in the samples\nwere quenched by using 6 M NOH solution. The si\nles were fered by syringe membrane fer (04 ym\npore iae to remove NiO particles. Analyses of iia and\nemaning concentration of 4-CP were determined with\nKnauer HPLC instrument with a reversed phase CL ea\numn (Erouphere 250.46 min). The injected vlume of\naction solution was 20 pL. The moble phase was pre\nvared by methanol and delonized water {containing 2%", "ee\nhemi ee sping par & UY emting ters 8\ntrl note 7 due wale cong ote", "ore 2", "Materials and methods", "Experimental set-up", "Procedure", "Analysis" ]

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[ "= lL\ndd as\nTS CS aa ee\n-<—— Sa, &\nSS “tT\n== Ss\nEEE", "" ]

[ [ 209.88, 104.9, 385.43, 692.35 ], [ 123.65, 709.13, 143.43, 718.29 ] ]

[ 103127.26474029437, 181.1802704082802 ]

[ 5, 2 ]

[ "usuially investigate more than one Single Nucteatide “oly-\nmozphsen (SNP) simultaneously. However. the author\nend to report only SNPs with mote favorable resus, a\nsell ds toneis uae: Eevamala pemetic canals", "ee eee ee ee\nsuggest the existence of publation bas under the per\nele made and the recessive model. We have confined\nhat the precampsi rk assoclated withthe ACE.D-\nele may largely bea esl of pubeaton bis. Note tha\nhe publication bas o repoeting bas i the HUGE eee\nsriace frorn particular sources, Genetic association studies", "See eee eee ee ee\nmethods that use smoothed variance estimates to replace\nhe asymptote variance estimates in Eger’ test when the\nfect sine ls the ods tte. This soothed vatance re\nduces the colton between the etiated odds rai\nands valance. Using Thompsons mathod, we ino\nfuced the parameter f° of between-atudy heterogeneity to", "Figure 1 Empéical type | error rate. Empirical type | error rate with respect ao she number of included studies and aiferent OF values and\ntoate a Tipe era of test eter b pe ere 10 that eter) al ghee", "ae onenene\n“ eo ae SS\nie ree cee I rsa\n: ct i ieee af |\n{ ea! pe =\nre) a .\ni aa saa ne\nSige asa =\n; ‘hg\n. SE Bet\nost) =\ne en ‘ a ise=t—t pet\nEe esos\nGeno =\nas a\nPihySaid ; ms\n(= Ke % WV\nix us 1 —— West om\nbo mi", "ase positive results under the dominant model (y+ ws\nMf none of the other eight tests found asymmetry in ths\nop. The postive results gen by Egger’ est, Harbord\nst, Peles st the AS-Eer ts, AS-Begy test, and SVE\nest forthe DD vs Il group may have been caused by the\ninflated type I ertor rate under severe heterogenelty.", "" ]

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[ 1, 1, 1, 1, 5, 3, 2 ]

[ "Our Eeaework Kiendilieg thane core arene wich ane ky\npotheszed to conebute to state balding, which ae (1)\npacity and willingess to provide cote service ta the\npopulation, (2) legitimacy, and (3) peoviding secur and\nstably. These ae broad supported within the pia\nences and economics erature (18, In partialay\niakeroll [19] argues that yovernance reconstruction”\nfailed slates and post-conflict societies is articulated\naed eee die", "Al he OECD augnment om the Enkage between effect\nveness and legacy shows, thee thece dimensions\nrem necestarly oul linked. This constitutes the base\nithe \"whole of government” approach tht the OECD\nund many donors are increasingly adopting i thee itr\nrenton in post-conflict and rage etn, negating de\nfence, diplomatic and development agencies [2123 The\ndances erature generally ienties the same [24] o\nar hice dimensions of state-building, the Worl\nDevelopment Report 2011, for example, sues the abit\n2 provide secu, justice and jobs [25], while the\nDepartment for International Development (DFID) fo\names on politcal setdement and processes, cote function\ntad expected functions [26].", "other authors (see, for exampie, (2/1) make a slighty\nlferent analysis of state-building, diferentiaing be\nween constitutive and outputs domains. Constitute\nJomins include poliialsetlement and rege, seu\nty, Fle of la, administrative governance: whl outpu\nJomains incade service delivery (health, education, ut\nes, el), Jusice system and. processes and economic\ngovernance. Sanaly, Halder [7] makes an inteeting\nlistincion between tangible and intangible aspects of\ntat-bulding. The Gest group includes actions such\nJemoiliang soldiers, restoring infrastructure, bulding\nsttutions and providing services, while the second in\nJudes promoting positive state-sciety and ita socket\nlations: restoring/ generating rst in goveenment pub\nle istutons and among clizen; and fostering solo\nsolitical cohesion.", "‘Beed cx thls evstew of Che Unecasticnl Mecnee on\nate-buling, we Ment two pose pathways through\nwhich the lngtimaey of state may be increased with\nSinuus Ea", "Un a sense, These pathways Could be seen as pertaining,\nspectively, to the tangible and the intangible aspets 0\nAa ballin deol hove", "rin Gevelopment clearly intersects wit state-buneng\naa wider web of human, isttutonal and economic\nevelopment. State building per sei a tlavely recent\nconcern for economists, who have, however; been tr\nted in the role of inaituans and human capital in\neconomic growth and development fora longer tie\n28) Thre Isa well-established Iterature on the role of\nwhat economists cll human capil often narovly\nunderstood as (formalschoal) education, in generating\nsonore growth though innovation and gains in prod\nictvity [29-1]. Economie surplus and growth ate, i\nen, perceived 3s fundamental elements fo the emer\ngence of sates, which are deemed ae resting on the\nprotection of productive economic interest (expecially\ncut) in exchange for taxation [32]. Contrary t0\npostwar gro theories 33, recent neo-asieal growth\nhele argue that human rather thin plyseal capa\nrlocd enias ofan a", "» Reconstructing legitimacy, Le. \"the acceptance of a\ngoverning regime as correc, appropiate and/or\nTigh. Legitimacy doesnot const only\nprclpation, inclusion, accountability and\nontstabiity(leions) but also refers to delivering\nServices, which links othe “ellecveness” dimension\nbelow. The bilty to deliver scl services sen to\ndemonstrate government wilngness and caput to\nrespond to eltzens’ needs and demands [9\n\n+ Revstablshing security, which includes effective\ndsarament, demobizaton and reiteration\n(DDR) processes\n\n+ Rebling effectiveness, which refers tothe delivery\nof coe sevies (heath education, eect, water\ntnd sniaton, nfastructre tc) at the ceateal\ntnd sub-national level, Economie governance\ndso included here. This alsa recognized by the\n(Organisition for Economic Co-operation and\nDeelopment (OECD) [20), which argues that, in\nturn, che integrity and effectiveness ofthe cil\nservice will influence the legitimacy ofthe state\n‘The link between the presence of el servants\n(eluding HRH) and eglmacy af the tate therefore\nuns in bath ways and whle he presence af apa\nservants eset to ensure the fanttoning of\npubl drinktaton and service provision, thee\npresences untly nthe oa abeence of state\nLoni", "nptnhirennahinnnd-ainemaionirniaans A\n‘erent leading to increased sate responsiveness t\n‘elzns' neds, which i tue inzeases legacy in\nthei eyes\n\n2. resence of publicly employed HRH (ll servants)\nleading to the presence af alginate and responsive\nStat, which iceeases trust and legitimacy ofthe", "The “building blocks” of state-building", "state Subaing and’ human, institutbonal and economic\ndevelopment" ]

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[ 23455.327399720845, 37493.966936689336, 42617.00244360836, 8955.025685753208, 6770.2416352164, 48905.656768944114, 63650.94283334073, 15611.971681097057, 1678.8299320142396, 2898.931059707422 ]

[ 1, 1, 1, 1, 1, 1, 3, 3, 2, 2 ]

[ "may not only go some way fo explaining why Chere are lew legal approaches that\ncn be used to lit auch practices, but also why various negative effects sight\nsce ds es ok ee Ca", "ie COEEE® OA MEM CONEDETCRNO, OF Ceres Lk ee ee Ceo\nae of many fos) sno a tern that ne ids realy in legal erature at eas oth\nthors knowledge It isnot something fr which in most junctions there ia eeadly\nlube legal efsiion. Indeed, most erste deing with criss communication\nate communication in general sot legal in nature. Depending onthe exact dicipine\nvolved or the particule context at pay the focus may be oa the eleay of such\nses, the form they take and, in many instances, the problems that arise theretrom\nsuch dscusions the precise deny ofthe author ofthe communication (or his or he\negal status) 1s not something that usually oeused upon. The focus is usualy eather on\nhe content and the forts of the communication in general, This isto a certain extent\ngia. Most of the academe and societal densi concerning cis communication\nor eample concerned with the elctvenss of ptcular communication stati\nparticule contest On other acasans decusston may be focused on the neal\nsiicts cached Wy wach aceon", "eS Se\nay exe in terns of crs communkalions. In dcusing what communication’ ial\nsully constiutes, sof couse important to recognise that such communication ca\nary enormously in both for nd content I not poable to describe such actives in\ncanis or exhaustive way. In terms af the form, communiation in general could take\nhe fort of verbal address, the distsbuton of physi! mater (such as pamphlets and\nposter) letter or emals and ever increasingly, the use of communiaion on vale\nforms on social media More specially with egard to ess communication the type\nof form used will depend very much of the circumstances in question and the target\nutence* Often several forms may be used to dsterinae the sine mesage ln order to\ncach a wider audience. Its not only the shee yarationavaale in tems offer that\nmake an exhaustive disruption impossible bu ao the fact that given social and techno\ngia changes and evolitions, new forms of communication ate becoming ever mot\nctv. nthe domain of rs communication the use of soll medi far of com\nnication have become ever more popula including in the contest of public heath\nise\" Such mathods allow public authorities to harnes the powe of pete indus\nsh organisations to further disteminate their desired mesage. Given the constant and\ncessant evolution inthe nature and scope of social med simple definion of such\nprocesses s largely impossible (even if ts were not the ease i would be fr beyond the\nscope of this paper).", "ne Ee Se, ee ee ee ee, ee\ncontest in question. Within cris conte, this could fr example inole the need t\nake particular security measutes (eg i incidents related to disorder oF toes).\nvice on where particular forms of healthcare teatment (eg, in an epidemic) should\nne sought or advice on where food and shelter can be found (e.g. within the context of", "What is communication (including during a crisis)?", "impossible to define in terms of form or content" ]

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[ 1, 1, 1, 1, 2, 2 ]

[ "egress Leet vein etwas oe Cri to Doth the seule ancl Runction cf leewes. A cacawing bocty Of racers\nwerk as inked lef vein network structure to the physiology, ecology and evolution of land plants Inthe process,\nmule inetutons and individual esarchers have aeambled collections of cleared Sef specimens invtch\ncular bundles (veins) are rendered viele. nan effort to facitate analy anc cigtaly preserve these specimens\nrigh-escuton images are eualy ceated, ether of tte leaves or of magnified lea subfection. na Few cate,\nlection of digital mages of cared leaves are avaiable for use online. Honevey, these eolections do not share\n-ommen platform ror i thee a means to cigtaly archive eared let images held by indviual researches (mn\nston thas held by isiutons) Hence, hee a growing need fora dtl achive that enables online viewing,\nSharing and disseminating of cleared leaf image collections held by both institutions and individual researchers.", "erent Ne eee Leet iiaepe Eitan Hyeeth tesa ea be Or Dane Weare, een. a a STE\nof reserchers to cotbute, acess and share cleared leaf mages. Cleared eavsD8 leverages resources flare cae\ncrated calecons whi enabing the aggregaton af smalcale collectors within the same anlne platfom,\ncearedLeavesD8 fs bulk on Drupal an open source content management platform, flow plant Bolan to store\nea imapesonine wth coresponding metadata, share image collections with a user community and discuss image\nand colton via a comma forum We provide tool to upload processed images and results 0 the database vis 2\nweb services client application that can be dowmloaded from the database.", "a cect cath sca sewer lst ng sm hc haa Maal\nbetween ues and data wa an itutve we interac, The web inerface allo torane of ge cllecone and\nmegiates with ef mage ais applications va an open application programming inte'ace (AP. The open AP\nlows uploading of processed images and other vat data 1 the database futher enabling strbution and\ndocumentation of analyze data within th community Theta database's seeded with nearly 19000 cleared eat\nmages representing over 40 Gof image data tense storage and grout ofthe database is ensured by\nsing the data storage resources ofthe Plant Discovery Environment. CearedLeavesD8 can be accessed at\nhttpy/clearedleavesdb.org.", "Keywords: Database, Images, Leaves, Digital archiving, Digital curation", "interconnected’ set of veins present in a Kea! Carbon, nu.\nvient, and water are tatsported tough xylem and\npoem contained with the vascular bundles that cons\nute veins [2] In addition, wens confer mater strength\nothe leaf du to the higher stiffens of vine elative to\nother leaf tissue [3:4]", "rhe leat organ is the site of the majority of primary\nproduction within land plats. Leaves vary in shape\ncompo, colo as well as the structure of thelr ven\non networks [1] Here, we focus an efforts to describe\nand analyze the last of these characteristis: the ver\nitn network. A leaf venation network represents the", "ee Se eee eee ee\ninterest due to multiple hypotheses inking venation ne\nworks to changes in leaf pyilogia ates [5] and to\nhe diversicaton of early land plants [73], For example,\nincreases in the density of leaf veins are hypothesized to", "Abhiram Das’, Alexander Bucksch’~, Charles A Price® and Joshua 5 Weitz’", "ClearedLeavesDB: an online database of cleared\nplant leaf images", "Abstract", "Background" ]

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[ 49049.4458512289, 35965.4646646434, 38375.36580826063, 3266.7973286894266, 14797.21057073865, 16593.482691585552, 13672.883836138994, 4132.20738839882, 16708.3638838029, 453.70184174999304, 655.0555694299983 ]

[ 1, 1, 1, 1, 1, 1, 1, 1, 2, 2, 2 ]

[ "Sregnancy outcomes were compared to a contro! co-\npart 0627? women delivering at cur hosptal over the\nsme time period (January 2005-uly 2011) previously\nreported elsewhere [12| Ths contol population was\nepresentatve of «tery referral obstetric population\nvith 18% prevalence of conic disease, excluding pre\nsting renal disease, hypertension and dlabetes. Fisher’\nact teat was used for bvuiate comparion of dicho\noie dake", "TMS manuscript describes & service evaluation and did\nnot reguire formal NHS Research Ethics Comittee re\new, The study ws designed to measure curent cate\nwiththe ain of eablshing the standard of pe-pregnancy\nrourseling for women with CKD at a singe tertiary\nentre, with reals that would not be generalizable out\nde the assessed area of practice. The anal of exiing\nlla was performed by the det cate health tar and\nsubsequently anonyrnised.", "a\nusted om the basis that there was no. deviation\nrom normal clinieal practice. In addition patelpant\nwere informed ofthe rationale forthe study, the vol\nunary mature of the questionnaire and the anoayety\noftheir response with informed consent being given\nby return of the questionnaire.", "Other thes che Cine taken te comglete aac) rete\nhe questionaire thee was no additonal burden\nsk for putiipans. Although there are ao explicit\nciter for prepregnancy counseling, our use of the\n2001 Institute of Medicine dimensions of patient cae\nmeant that this study was registered and approved\nin audit at Guys and St. Thomas’ NHS Foundation\na", "78 women wih CRD stteacied Her pne-pregeancy come-\nselling between 2003-2011. There was trend fora i\neasing number of referrals overtime (see Additional\nle 2: Figure SI). Age ranged from 2116 years with\nmedian of 33 years. 131 women (73%) were nulliparous.", "the 179 women fad 36 chagnoses (see Baie Be ine\nmedian number of diagnotes per patient was 1\nhough some women had more than one dlagnois with\nhe potential to impact a pregnancy (eange 1-3), fo\nexample, diabetic nephropathy and subsequent trans\nplanation, or hypertensive nephropathy with secon\nlary glomeruloscleresia.", "The severity of renal impairment pre-pregnancy ranged\nfrom CKD stage 15 (o0e Table 2).", "‘Pre-peagmancy Blood presence records wese avaliiole\nor 167 women (93% of cohaet). 56 (34%) were normo-\nensive without wealment (2140/90 mmHg), 89 (534)\npad ontelled blood pressure on ants hypertensive\nmedication and 22 (138) had uncontelled blood pes\nure (2140 oF 290magHy) despite treatment. 77 women\n3) had detectable proteinuria and 18 women (104)\npad 2 story of neplvotierange proteinuria (33g\n> hours).", "Motication dita wore avelletie Mer 175 women: 09\nwomen (49%) were counselled reparding a required\nchange in medication for pregnancy including dco\ninuation and/or aubsthuton of angiotensin, receptor\nlocke in 46 women (26%) and mycophenolate mote\n38 women (10%). Other medlcatons of relevance to\npegnancy included bisphosphonates, diuretics, war,\neduca", "7* Women responded to the questionnaire {response rate\n10%). 65 women (90%) stated that they found the clin\nformate, 6 women (92%) reported tha they under\nood the advice given and 64 women (9%) ft that the\nConsultation had’ helped them decide about purauing", "Reiiie 1 Gelegmenss in mapenen eqvendiing for pay-pegeenry\nae", "Table 2 CKD stage in the pre-pregnancy counselling", "", "egos Number of patients (36)\"\nsha eshpahy pou\npeer netcpty ne\nney pancreas tap ne", "", "Ethics statement", "", "Demograpinics and clinical presentation of women\nstanding the linke", "Questionnaire data" ]

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[ 22722.56162747671, 23445.194743779954, 18063.697620289517, 19592.17005783459, 13726.273676533485, 17712.94957448519, 4112.55300850264, 22595.12074573338, 20446.262114309706, 13780.316020462662, 2856.3348096275004, 2452.947212507832, 3106.6716963549843, 39159.97214945711, 22794.447381782928, 693.1437516974111, 384.21925715000543, 3046.3211360025452, 797.8680109146517 ]

[ 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 4, 4, 2, 2, 2, 2 ]

[ "ne aie in en we fener we meme\ngudance molecules in. topography (runing of branches\ndonvergence (es efletent projections onto one cl swell\npestyrapie compartment es arent denarii snervton\nspec brain ates\" ™ Changes cucuing pyar\nmorphology in terms of expnsin of denaite complet at\npeaealy aptent in lye I Furthermore, during the fs\nour postnatal wees the lel inhory ntemeuten nets\nhe mPFC undergo an extensive process of maturation both he\nlevel ef insane fanchonal tr well at two prope\nGen that bay acts eco i thought wo Cnt\nhe proper constacion af crcl etwas the renee\nSap connecity Inher and excatery etn led\n ruslocanartel pledicher iad fae-¢asen of corupler taleater", "a a ee oo\nlies upon the guidance of rowing axons to tel snap\nlige To help them tnd tht sap porte, devlopin\nsans afe Upped ith a highly metic sensory sicture he\nsom cone Groth canes te insted to flow pedeter\nmined. wajeceis by heterogeneously dstibuted guidance\nmelecues in the extacar envronnent Bing taro\ngudnce matecls to tector complees othe srt con\nfae intates iacellar signaling evens, which mda\ngrowth cane morphology ond drectonaltyaugh oes\nmedication of the cjekaeton ton guidance moles a\nst as atvactats or repel thats, eter dreting fora\ncones toward 9 speche structure or preventing thet om\nsteing inappropriate regions Furthermore, these Coes os\nmenbrane-tocuted macedes scing aot anges\nube agents with ong stance fect The responses\ngoing axons to pac cs however, may change as the\nrow toward the final targets For example Semaphin 3\nch a bidrectonal glance cue tt tough ining vith\nNeurpiin2 aly repels dopamine sons tom the tos\nyetal egret aca onthe ay athe mPFC and ater are\ntnd vents them within the PFC\" Vine the axonal gon\ninh en ged he ope ae rap tc\nadhe\" New formed synape contacts change the\nuncon properties a development progress ud conte\nfo the maturabon and functioning af a axea™™'™ Funhormore", "AS mentioned above, i rodents and omer pnytogenedicasy\ntigher species, the PFC snot one homageneaus col region\nbat comparenaised io’ numer of tucraly te\nneon sinc petal reas each of which though\npen chance input por he\nfons. Within the medal porn, the ani Gute C3\npsc (PL) an inaibe (L) corte gue 3) and dora\npain ats can be dete an dal wel\nsnd the gran isl cores Te aiferen tes of the\nae ee nrunel to vee ote bea ee nee", "a teh enn Cataes tn than Cae: Coeeerie mitaina, cudduana tanatiinn bad cone tedtinh olf whith sey tn tian bo teal te\nreurodcelopriental events inthe mPFC (preseration migration, guidance targeting and connectivity of which some can aso be found in\nSec sesh es nar neers dudes fab ADE chao Tete se ae gee\nreraereopmertal Cvre'Cp ngs soien Gf corte! pa! OR dang newer C_ growth core: nab Cre\nrermetron fe ntemeate progenitor meamesste ane li migatng Meuron PN, poston neuron Pi. prelim cote #2\npverate zone Rada i Commsurl ond concoct! pojetan neon: respecte) bearer! poets Nero\nSil garg cenenlon mir Hn sd pn on) const pean sear to mesg amc re", "aE\net) — a)\npoten ow curs\nmigfition ——*\na\nAe es —\noe ae\n=", "RAN GUERERCS, Cage SeeCHOR ome! Emapes Korean Of MP.", "—_<“«" ]

[ [ 311.36, 435.72, 559.4100000000001, 578.23 ], [ 45.35, 457.82, 293.40000000000003, 734.9300000000001 ], [ 311.36, 612.99, 559.4100000000001, 734.9300000000001 ], [ 45.35, 327.02, 559.4, 408.11 ], [ 140.2, 59.6, 464.65, 321.69 ], [ 45.35, 435.93, 283.63, 455.94 ], [ 311.36, 591.05, 542.81, 611.1099999999999 ] ]

[ 35345.462820049375, 68728.81843304634, 30244.305728990585, 37791.02428601915, 85036.21122300003, 2706.3007141286216, 2997.557039958425 ]

[ 1, 1, 1, 1, 5, 2, 2 ]

[ "p= OEE Ne OS OB ES 28 p= O09) anc’ te os\ncore (BPD-A: b = ~A7, U= -420, p « 00; BPD-R\np= 118, ¢ = ~429, p = Obl: HC: b = -057, -398,\n» = 001). When predicting the BSL score simultaneously\nbythe RSQ and the SES, only the SES remained sg\nleant predictor (BPD-A-b = ~06, t= 418, p < 00\nBPD-R: b= -O6, t= ~29, p = 015; HC: b = —Ot,\n| = -265, p = 010), wheres the eifect of the RSQ\nlminished (BPD-A:b = 02. €= 101, p = 318; BPD-R\np= 002, t = 05, p = 959, HC: b= OL, ¢=\n» = 400), The SOBEL zest revealed an indict effec\nDF RSQ om BSL dough SES inal groups tht was sg\nicantly higher than 2e0 (BPD-A 2 = 212, p = 00k\nBPD-R: 2 = 236, p= O18 HC: 2 = 216, p = 031). Se\nane", "a\nting scores in the HC and BDD-A groups, a nom\nparametic bootstrapping method was additonally used\n eatimate the confidence interval ofthe indict effec.\nThe indirect effect was different fren zero with a prob\nbly of 9% for bot patient groups. For the HC, the\npotstrapping method could not eonem the mediating\n-fiect revealed by the SOBEL 2-test.", "ncirect elect of Mond on Boh Trougn tne ee tp > 99).\nJn contrast n the HC group, the SOBEL 1-test indicated\natthe BDI score medter the effect of RSQ on BSL\n2 = 225, p = 25) although ths could nat be con\nirmed by the boolstapping method. To take into\nrecount the influence of depressive symptoms on the\nedn role of sell-etern inthe elation between RS\nind borderline symptom severity, we repeated the mai\nalee with self-esteem scores corrected for depressive\nymploms. Sine bordertine and depressive symp\nhare lage portion of variance due to an overap of\nymploms (57, we corrected BDI scores fr common\nrarance with BSL score, and used dhe exultng BDI re\ndual na second step to cortet self-esteem scares fo\ndepressive symptorns. Meditonal analysis using thes\nsorvected self-esteem scores confited our finding: the\nSOBEL s-test reveled an indivect fect of RSQ on BSL\nthrough the SES in all thee samples In both patent\nroups, but not in the HC group this nding was con\nrand acing Sus hnstebenee eaeaea.", "A CORIO BOE ce CU-Cis Ot Oepceeeve Farpcane te\nhe association between RSQ and BSL, we raleulated\nmediation analyses using the BDI scree at mediators\na oth patient groups, neler the SOBEL 2-tst noe the\nsootstrapping cnethed supported the existence of an", "oe\njute and remited BPD patients and the ration of this\ncognitive alfectve disposition with chldkood malteat\nat ed ealbaoieees", "As we hypothesized, BPD patients reported markedly\nnigher RS compared to healthy individuals, Both increased", "ao eee eee", "oa eee ee\n1 : ops . t °\ngobire ot tier |i", "" ]

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[ 39457.664915832225, 21049.87919229269, 55009.76994940173, 13683.001604421996, 9237.195034252014, 5267.787810290465, 4638.826602692716, 127064.00744889991, 570.2673805300146 ]

[ 1, 1, 1, 1, 1, 1, 1, 5, 2 ]

[ "Focal segmental glomerulosclerosis (FSGS) Is a kidney disease with progressive glomerular scarring anc a Clinical\npresentation of nephyotic syndrome, FSGS is a common primary glomerular csorder that causes rena dysfunction\nhich progresses only overtime to end stage rena disease Most cases af FSGS ae idiopathic Athough kidney\nvansplantation& a potentall curative eatmert 409% of patients have recurence of FSGS ae vansplntation. In\nhis review a rie summary of the pathogenesis causing FSGS In humans ven and a variety af anal models\nvse to study FSGS fe clecused. These animal models chad the recucton of renal mats by reecing 5/6 ofthe\ndey, rciton of teal mass due to systemic seater auch as hypertension typeripidema or SLE, drug-induced\n=SGS ung adlamyein, puromycin o steptazotocin,wrusinduced FSGS, gneticalyinduced FSGS such as ia\nMy inactvation and acini 4 and podocn knockouts and a model fr cculting permeabiy facto. In\nation, an animal mode that spontaneously develops FSGS is dscussed. To date there Is no exact understanding\naf the pathogenesis of idiopathic FSGS, and thee sno definite curate weatment One requirement fctaing\nFG research ean animal mod! that resembles human FSGS, Most animal models induce secondary fers of\nFSGS in an acute manne. The deal animal model fr primary FSGS, hoNevet, should mimi the human primary\norm in that & develops spertaneoutly and ha slo chron progression Such modes ate curetly not avaiable\nWe canlude tha hee isa need fora beter animal made! to investigate the pathogenes and potential\ntreatment options of FSGS.", "Reynwords: Focal Segmental qamnenucsclerosis, Anime! mocel, Remnant kidney, Adriamycin, Purrrycin\nsminonucleoside-induced nephrosis, hiv, Mpv-17, c-actinin 4", "ot proteinuria, Aypoabuminemia, hypercholesterolemis\nind peripheral edema [3].", "roca’ segmental gomerwosclerosis ('SG5) is a disease\nvith progressive glomerular scarring. Studies [1.2] hae\nhows that podocytes are the main cls involved in the\nevelopment of FSGS. Podacytes are epithelial cells of\nhe scr layer of the kidneys Bowmans capsule. The\njunction i to form a flralion structure that prevents\npel asta the urine. Destrtion af podocytes induced\nby collar sree eeauls in across of prt (egmenta of\nhe glomerular capil ina minority Hoel of glomerl\nthe aclerois continues, glabalglerulosleross wil\nJevelopCliialy the loss of podocytes and thei za\non function results in nephrotic syndrome, consisting", "USGS Ras an incidence of 7 per million, and in 20% of\nJuldren and in 404 of adults isthe underying cause\nnf nephetiesyadeomse. When FSGS ls accompanied by\nhigh peotsnuria lvls atthe time of presentation, 50M\neases progres 0 end-stage renal disease (ESRD) wih\n10 8 years, making FSGS causal or 4 of al ESRD cases\n3]. After kidney transplantation (KT) for primary FSGS,\nhe recurrence rate is 40% [4],", "an BO OF BSS Patients, the etiology is unknown. ‘a\nhe remaining 20% of ese, FSGS develops secondary to\nnher underying diseases Genetic causes (@aciin 4\ntations) were found, as well a forms that were HIV\nin-assoiated, induced by drugs auch as interferon,\nused by a congenital reduction in eenal mass (unter\ngenes) or by reduction of renal mass due to systemic\nMocave such as hypertension [6", "httpe/ www. beomeccentraLoonmy 1471-2369) 14/74", "Sylvania ML de Mik’, Martin J Hoogduijn’, Ron W de Bruin’ and Frank JMF Dor’", "Pathophysiology and treatment of focal segmental\nglomerulosclerosis: the role of animal models", "Abstract", "Background" ]

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[ 82808.56661062129, 7630.2428521344555, 3828.109139015898, 33416.55879526865, 20804.295493060723, 20852.765964075457, 1475.1927194905056, 4404.381850503531, 24122.454620650038, 453.70184174999304, 655.0555694299983 ]

[ 1, 1, 1, 1, 1, 1, 1, 1, 2, 2, 2 ]

[ "To padeceand the Seactional selene commen for the\nast-evalving of slow-evolving genes among differen\nsubgroups of mammals, we categorized the shared gene\nthe lineages of primates, age mammals, and rodents\nThere were 185, 609, and 695, fst-evolving genes in pet\nmates large mammals, and rodents, respectively, and\n$55,600, and 730 slow-evolving genes. However, we\nnly found 15 fs-evolving and 72 slow-evelvng genes\nhat were shared by all nine species This result suggest\nhat fst-evalving and slow-evolving genes tend to be\nade’, hneage- of species-specific However limited\nnumbers of shared genes may ail lead toa significant\nsulin of chal Wectane tratie 1", "Ee eS eee ee\n105, 127,48, 49, 23 132 and 446, respectively in chi\npannee, orangutan, macaque, horse, dog, cow, gues\ni mouse, fl opossum and platypus, respectively) can\npe obviously seen from the degree of vasabilty [60\nThese two ease studies provide a footnote that supports\nee ane ote wee", "AEhough we have only compared hamen genes {at 4\nference) with those of other mammals, instead o\nJong pairwise comparisons, our coclasions can stil be\nly extended to broader spectrum af mammals, o\nven ather vertebrates. To validate out analyses, we\nlected two representalive proteins, ISG20 and RAB30\nbased on orthologs fom 20 and 22 mammals, respec\nively rom 87 shared fst-islow-evolving genes i nine\nspecies to demonstrate their degrees of variation and\n-onservation (Fue 5). The fast volving 1SG20 (ranked\n25,71, 94, 69,95, 128, 321, 58, 82, 260 and 423 in\n-nimpanzee, orangutan, macaque, horse, dog. cow, gu\nnea pig, mouse, rat, opossum and platypus, reapecthvely)", "in Hs ately, we Carried at am evolntionery anntyels oF\npuman protein-coding genes that are shared among\nmammals We not only demonstrated tat Ka i useful\nind sable indicator far studying mammalian gene evo\n\njullon, but we also feveaed thatthe rate at which\ngene evolves i elated toe function. In paiculr, we\nfound entichedimmnune-related functions in both fat\n\nvolving and slow-evolving genes, and slow-evolving\njens were sigalcantlyeneched in functions edated to\nhe celzal nervous system. Furthermore, we observed\nhat slowevolving genes tended to be expressed a\nhigher levels. Our results provide valuable insights fo\nhe funcional charactervaton of genes and gene asses\ndifferent mammalian lineages.", "SOF RE ER WEN ECE ee eee Verne\n161] (hitp://heww blomart org); hitp://wwvw.ensernbLorg/)", "Table 3 Functional enrichment of fast-evolving and slow-evolving genes in large mammals", "ee eeeEeEeEeEeEe EE", "", "rhe shared last-evolving and slow-evolving genes among\namas.", "Conclusions", "Methods", "Data acquisition and quality assessment" ]

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[ 35167.949960191734, 17934.901584025472, 35990.94875503704, 37684.192521777004, 5339.877418154385, 3784.8915319407606, 3991.266544585291, 124578.206592419, 2874.5600638111355, 642.0048858074588, 471.28584011655767, 1678.5883878986351 ]

[ 1, 1, 1, 1, 1, 1, 1, 4, 2, 2, 2, 2 ]

[ "be door % ungufed (fore) capes A female\nripoyae commented “| dove tin is gh fr", "HY & mecas being equal, let's compete. ft shouldnt come just\nanus sone Face bcaefv ae shen\nJe yr uf nd yeep ea wit\nnie ponte cea", "net becweenpromasng eq opporenty 2 ding ws", "-We fad an appicatan lee, | would want to maybe t» encaurage\nven be ea, btn ta ek ete fico\nef da wae ato pr of Ses Be", "wae percaved 2 “proce reed For nano", "Men hove « biolegical make-up that makes them wuines-\net eppeaanc Seven gt Be\nvc ewe re ely mpl eed\nast be Foe a tn ih Ho\nvon nth nasty wh ee fiche nee,", "gt) nt\nrasment and responslityshting was cere fom\nsehlighted 2 vsrontype by onan ube snan, hat they are", "leekitlecclardl aces eieikmenicneticalatiasened", "We are odmiang @ weakness, but...1wonsan can help us nat jump the\nun cnet ig Ma aes oa ey\nve oedon ro ara ek\nmn mare ey ed ene sea gS\nre an ap © et Oy By meds a\nrene ooo eects tutti eon edowwnal bap", "(UPSO focus group participants’ comments suggested", "fable Ao. Gender essentiotst and male primacy stercegpes about male and fermale workers ond /eoders : 2°50)", "Table AG. Gender essentiafst and male primacy stereaqypes about male and fermale workers and leaders: UPSO", "By mare, nen are bora wth adept?” = “Hep\nA man & more ently gle han 3 ere 1 ce ore [snd mars respon\nere product 1 Noe rey quae\necsle to speararcs\"\"Man by rare euly pet + “Sek revenge towards mle 2\ntrove when thy ee caring. pots ay «we ped ob rsh may have babies the ent\nIve to fed on ps {kes worn, your mind cn be bere by probleme you\n+ \"Worn ar rel uggs dred", "“Dench + \"Not eompeten enough”\n“Wen men bay, thy ink thy cn ke snping fom would not be stale or igh poston ht aga\n(ere borden 20 they sare ing or 0 vor Te of pons" ]

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[ 14466.797969595063, 7236.310866170563, 5921.849563084543, 6905.7288300583605, 6152.655694300309, 10270.976838114439, 12492.427880700212, 6010.045672076056, 17639.58610084327, 4729.678036483005, 3254.263798290631, 3235.845468011743, 85954.63685030007, 48151.23994278 ]

[ 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 4, 4 ]

[ "nependient UPS). iin the mentioned study, earlier expres:\nion of HATES in response to salt stress was observed\nleaves of bread wheat eather than rats, Additionally,\nude high NaCl level (200 mat) weatment, the allele of\nD genome (HKTLS-D) showed higher expeession than\nhe allele of A genome (HKTES-A). We found that pro\nater region of HKTIS-D has jasmonie ack respons\nJement [15] which this element is not present a\nHICTLS-A. In other words, the observed difereaial ex\npesionpatern of HKT canbe explained by diferent\nrehitecture of promoter regions tn the view of east\ncelabuence of regulary elements, This an encour\nging and moatly unknown tople for future studies.", "The coomlle of the PLANT CARE pasiyes of promoter\negjons are shown in Table 1. Interestingly, TATA. box\nahd CAAT elements were more frequent inthe\nTmHKT:S peomoter than TaHKTHS, The presence and\nhe number of TATA boxes can increase the quantity of\ngene expression. However, the exact activation ofthe pu\native TATA boxes in HK has not been investigated in\naboratory level", "Some studies suggested that LALA box has a variable\nposition in ~100 and ~40 nudeotdes fom the start\ncodon [16-20 In contrast, other studs argued thatthe\nfective region of TATA box s 3227 and can alter up\n050 nucleotides upseeam ofthe transcription ination\nite 16-19] It seems that postion of putative TATA box\nis wathdblo Neteeen cass pecs peonotore,", "[nterestingly, Sharma and co-workers in 2011 illus-\nrated that the presence of two TATA boxes at pos\ntons -59 and -359 and two CCAAT elements sting\n3 positions of -355 and ~500 are involved in strong\nexpression of AIX in Aspergillus Niger (211.", "ACCORENBY: T'S possible that eacly of the preaicted\nTATA boxes in the present study to have posite impact\noa HIT expeession earls of thr postions o the eo\nmater sagion. Consequently, we supposed that the in\neased number of TATA ous in promoter of TTI\nld wheat) compared i TAHKT:S (bead whet) ca\nwalt in higher expression of TmHKTIS.", "specific position of promoter (~30) ls mare effective than\nhe whole numbers of TATA boxes which ae spread\nrss the entire promoter gone should be noted that\nTATA boxes in ther regions of promoter suchas pation\nof 50s TKS ean fanelion in diferent stations\nch eater able tresses The ink betneen pos\non of TATA box and tissue specie expresion i als\nprobable as TnHIKTHS has sical higher expresion\nE costs catia: Gan faa loeee EPL", "PLANTCARE snalyeis detected Righ Mequency of\nTATA boxes around poston -50 (42/4/5052) i\nTAT whe ts TAHKTES promoter the peak of TATA\npos happened around psion 30 (-19/ 20) 22) 5)\nin our 20st, we sugested hatin high lity cond\nfon, D genome of TAHKT:S te mone effective than A\ngenome of THHKTIS and ToHIKTIS 12]. With eespect\nOthe positon of TATA boxes in TaHKTIS promote\nround postion -20), it canbe concluded tht postion\nof -30 is more important than pstlan of 50 inition\nof wanscripuon under high slit (200 mM condition,\ncatering higher level af expeession st TAHKT:S com\npared to TBHKTIS. in other wordt seems tht at ls\nseas: ldehs ninety dicien tea maar of FTA bao tn", "Another interesting regulatory element in comparison of\nPACTS with TAHKT! & CAAT box (Table 1). CAAT-\npax sequences have proved ps impact on quency of\nvanscrponaliaitation [23 Interestingly, alle Ise\nras of promote eons inthis study zeveaed the exist\nce of two CAAT-oxes in TmHKTES promater atthe\nange of ~80 t ~100 positon (-38 and 76, respective)\na contast, CAAT-boxes in promoter of TAKTES azo\nated out of -100 poston tm the start codon. Artange\nment of CAAT-basescloe to transcription start codon i\nTHK can lp wd what i beter esponse to ei\nTeenonial ona texuis tuphd actieuten ox uk.", "SCE RAE CPEREENS (PORES DOPPOLK? TO PRERNORAAN, FREIB-\nates ae univer signal of deferred gene expression\nInthe presen study, the asmonate response element\nMela) was two tines moe common Ia DATS than\nTaHKTI:S (Tbe 1), mona elved in plant adap\noa oblte ane sbi resis, and i accused tan\ndently in seaponse to oatnotic/ealt stress [25]", "‘thas been stated that expression of ThHKT1;5 is higher\nhan TAHATES under lowed salt sts G0 and\n100 mM Nai) [15]. So, ths salty tolerance in the\nTBHKTIS can be related to some elements in the pro\nmoter region suchas asmonate response element (Me)\nat was moe feguent i this plant Lnterestingy, thas\npen shown that aplication of MeJA improves the tle\nune under moderate sine steess (40 mM NaCt) in roe\nsl, but aati igh sity conditions (200 mM Nac\n26), which en parallel to cur assumption about the rl\nof MGIA in PUKTI:S) THHKTIS promote. Is pos\nble that the MoJA and TATA bones are not active i\nhigher salt conditions so the expression of HAT deczease\nToco in high salisty condition. However. the\nsmportant point Ua jasmonate response demeat ca\nuse salinity tolernce, a postive trait in salt environ\nsao ot lone tn loveteondcenie miei cmadions,", "Tie Yremioter ete Ae aewen At Hara Be\ncing element involved in hest stress responsvenets,\nore eguent ip TaHATIS-D than ToHKTIS. Thus,\nkey that these HKTR are expresed in rexponse to\nhigh temperature too.", "Phe promoter analysis was performed in all available rice\nHKT tranaporter looformna, separated into two subfarnilies.", "Promoter analysis of all HAT isoforms in rice" ]

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[ 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 2 ]

[ "a a See Se ee ee ee ey\nheight internal carotid artery to occde the origin of\night middle cerebral artery (MCA). After 90 minates of\npclson, the auture was removed to allow reprfisin,\nhe external caruid artery was ligated, the wound ws\nsed and the rts were allowed to awaken. Rectal tem\nperature was maintained (37.0 05°C) with eating ad\ntad lamp and blood pressure was monitored.", "EEE ORES EEE ae Ty OE ee Se\nsusion and perfused through the heat with parafr\naldehyde in phosphate buffered saline (PBS, pH 7.)\nBrains were dehydated in graded ethanal, cleared in 3)\nene, and paralfin-embedded. Seven micrometer thik\neal coronal sections were cut and mounted on gs\nides, which were died overnight at 4. Sections wer\nhen washed in PBS for 20 min, pemmeabilzed in 0.2%\nTitoa in Tris-buffered saline for Ih, locked using 5%\nnormal gost serum with 02% Triton in Tes bullered\nline for 1 hand incubated with pinay antibody in\nlocking bur at 4°C overnight The primary antibod\nsed were: ft ant-VEGP-B (150, Santa Caz, abit\nsneMAP2 (1500, Chemicon), rabbit ant-CD1ub\n1:200, Abcam), eabbt anl-GFAP (1:00, Sigma), and\nrabbit anti-von Willebrand factor (vwF) (1:500, Signa).", "Vn a oe\nmouse IgG secondary anubody (1200, Vectastain Et\nABC, Vector) in blocking butler for 1h, and placed i\nida peronidase conjugate (Vector) for th. The hose\nadsh peroxidase reaction was detected wih 0.05% DAB\nsnd 003% H.0,. Processing was stopped with H,0 and\ntions were imaged using a Nikon E300 epdluores-\nnena iatonller", "Sor caminobenzdine (OAS) salning. sections stalnes\ni VEG as doe were ered Pes coniaieies", "2 et ke\ntained with the primary antibodies Usted above wer\nwashed in PBS containing 01% Tween 20 for 1h ine\n\npated with secondary antibody in Blocking buf for 1,\nwashed in PRS for 1h, and mounted using Prolong Gol\nvith DAPL (1,6-damidino2-phenlindle, nvitogen.\nSecondary antibodies were Alera Fuoe-conjugated donkey\nsnimouse of ani-abbi IgG (1200, Molecala Probes)\nSections were imaged ona laser scanning canforl miro\n\nscope (LSM 510, Carl Zeles)", "a a a ee ee\nfrat brains showed increawed VEGF-A immunoreact-\nity primary in the Scheme border zone, a 1 3 and\n? days ater MCAO (Figure 1). Ths immunoreactivity\nwis astolated with call bodies of round and polygons\nnelle and was more pronounced at 1 and 3 than at 7 days", "Pippen 1 6 Km moraacttty in cavabral cortex 17 dais after ICAO, Top row, tap night comer sin the direction of the ischermic\nsenda greene are dea er ntaereanyna -machmer adres salvage tes", "VEGF-B (1 day) VEGF-B(3 days) VEGF-B (7 days)\n\nSa 2 See\nRamet tare bc bee ec 5\nWea ei asked Bader S's;\ncaste F thong\nvee iis: 1\nao", "" ]

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[ 21551.237664396875, 44442.38071205234, 20284.868283095188, 5252.771710613102, 26282.53816999425, 16574.510886520147, 7865.056311105145, 131680.98813999997, 384.21925715002 ]

[ 1, 1, 1, 1, 1, 1, 1, 5, 2 ]

[ "wath Great disect. Te Comman trend in Domechanics research #s (0\nonside! ddl paraters sch a5 leion manent peak vale,\nvtaton toma dane By Kaan eta =) ad then sta\nsteal test there ae sigan dferences each pane\ner betwen the patent and novmal sujet: However, achine\namin ook tthe complet of the data as 2 whale [0 ve\nomg hatains tht arse Kom pass testing sng ind\nial paaeters chery ning the chess and complexity of\nhe daa, For example, mache leming canbe sed to ies\nlcromjograp, tiene ad Wet: data om the tee,\nrprate haa patente mid ad sever knee OA scan 2\nere a [5 Feder et a. (6 ened systematic dferences\npete ely and med Eace-stesrtivie ga wg pi\npul component anal. a ths sy we ana pratt af\nound reacian forces (GH) to estimate ang a eject sede\nhe degiee of knee ON and to exact parueters tat deat\nte more electvly between atl and nee OK sujet To the\nses ofthe author knowledge ths the study detect\nng tne OA via analsng the GRFs using andor fret, We be\nve thats purely dat-denappoath lds objet teases\nsn pater well fr bath boll ed cel advancement\nsige by sal ea 7 Emphasis gen an detecting pa\neters ith psi meaning as unding s tht rere\nly eerpretabl even to aoa acai experte, The gudince\nules may be adopted in autine eal vst to pode support\nfo healvare profesional dng deson making Our Bl st\npysican when diagnosing new patients oo tain scents t di\nseen parionts.", "Se I ee\nscsminant anal after principal component aaj achieving\nram covet cssction Mote tien, Gs have been sad\ned. Wavelet anass by Mowsatidse a 10) has shaw tha 2\nction in peak aneit-petrio ground reaction fee ding\nhe stance phase occurs koe OA subjects (2 heat, 24 wih\nbe 08) They were grouped in bo, dette, and shee OR ct\nies with 2 93. performance A second study By Meghant\na [I clued the cuties of 2 pobooml expansion\nthe coufets of wavelet decamposton for 16 Bally abd\n25 tbifemoral koe OR subject A nearest neighbour chsser\nseed accra ang ro G72 to 1 depend othe et\nican,", "nee dreeaainn on adie Sonnet aides,\nAtehen 3) Mousa ea [10] and Mezghan fa [| have\nes, a detaed below. for ample Beynon et as] explored\nte seo saptalfiontaltrnsverte plane range of ation snd the\npak vet gun elon fee daring the sane phase oat\nted cadence. Tey mee abet disci kae OM sujet (0\n30 subject, 15 with Ene OA. ga eee pr Sabet) wing\nhe Dempster theory of eden, Depending on whether\nhe proposed metbod's heute aes ae corp by esc\nve tite or povided by an expert te yes a & perfor\nmance of 2 te S678 respective, a another sty by Belo\nsnd teen [3 5D patents wth en-tte knee OR and 63 co\nsd eoidcin vecicaans tat malin bios os mentee onina eee", "a ee ee eee\nJanine. Tat the zason why we relan fom abet\natheuteal pprsches uch a wavelet past decomposition 3\nJoe by Mousa ea | a6 they lek diet py\ncreation Moreover we cider sl the tal provided by each\nbet ater han averaging cons Us ode ocala the\nea GAs, as isthe ease of Meghan ea [I Averaging i\nars the nea subject arbi Whe previous work oes\not petting dtrteeucaien ur appcach pre Cin\nale coins ouput cater na yesooanaves, whit at\nhe same time reflecting the progresive degenerative nature of\nscars Very ew previaus suds pole am aerate 1\nsects pedir. Bayon et [proved a eel of bee! hat\ntity. Rally out approach does ht adopt a a Boe hes\nss Tin tee ane eeeancd to ee ot", "is wort mentioning at the ics of machine learning ines\nnt hae Tobe nee OA peditin For camp the authors Fare\na 12 applied rer etwas to pede Kee dation to\nent during walking based on ground vation frce and st\nnets measurements whereas Beg hd Kazsaan (13) 3p\ned suport vector mhies to dsriniate young fom eidety\npects Crplaling etc and Kinematepaateter and Mit\nta [eased Parkinson dete explating Ge According\nne proposed te here aking the pole af estimating the\npesca of Kae OA vin ave ted appcach that conctenty\nstale the most deities othe pt Ha\nrt ould ao beled to sae aol mussel\nacies ie back pi, gen the repective Kote pratt for", "epee Pu agintbors mein mirdsenactiaabe pinta iri\nwath gender and age mated contol subjects. We collected Io\nemotion data om 7 subjects wih Kae stout and 47\naly subjects The mean value an the sandr deviation be\nen pal a tee OA aes of ea. we\nced na eal pov fo hy was tied om", "ug, wih a ex he onl ae He\nhigh, wei", "", "", "", "", "", "" ]

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[ 77613.50958395656, 32256.143459489103, 36859.60389036778, 44090.64562716009, 34788.04152723774, 20884.19984437572, 2876.85317909273, 3182.651144729345, 9592.418844, 20538.340559999982, 967.7329568719142, 187.25723671009473, 187.19213287296589 ]

[ 1, 1, 1, 1, 1, 1, 1, 1, 4, 4, 2, 2, 2 ]

[ "The Tetle wetes OE EL Mele) aes ee\nood ad ibtum. They underwent surgery in the labore\nary of microsurgery under proper Technical supervision\nThe animale were anesthetized with itamuscular xylazine\n10 mgikg pls keane 50-75 mglkg. We used hee brands\nof 75 micron nylon 10-0 suture wire: Microsuture®, Poly.", "After sneethesis, the animals were shaved snc placed in\nrorzcr supine passion Antiepsie was made the ron\nand media thigh region. Then a transverse incison was\nade inthe thigh flowing the inguinal crease. The subcu\n\njancous tisvs was cesected toward the exin incision and\npigastic vessels wore cautorized and the femoral neu\n\nvascular bundle wae ‘denied. The femoral arery was\nndvdualzad va dasection ofthe connective esue that\nConnects to ether stuctires, A rubber shield was used\nor batter vaualzaton ofthe Tamora arery. The vessel vas\nhushed vith 2% idocane o prevent aerial spasm. A double\nlamp Was postcned between the inguinal garment anche\npegining ofthe inferior epigastic branches (cstaly) and\nhe atterictomy was held at hal distance trom the double\nlamp. Then, Stumps were propered by removal ofthe ad\n\nrenitious, ation with cating forceps and lumen iigation\nwith 5000 IU/ml sodium heparin.", "The clamps were appronched ancl faen sutured wih interrurted\nsure tough tho tanguaton fchniue (we anerar Por,\n120\" beteen the). The clamp was tuned facing the rear wal\nuta the ariecewl ire wae ended wth 810 stiches\non average. 8 the end ofthe etre, the clamp was removed\nand Placed in prensin balance pre-weighed gauze for 3 me,\nAer that, the gauze was weighed once again fo quanti the\nnastomesis bleetng by subracieg the fnal weigh ofthe\ngauze fom is fore weight. At this time, the anastomoss\ntency a est. The coaure of he cision was perormed\nrough simple sudure with non-absorbable nyion 4-0 wire.", "sebtesaned ty 6 theme lg sen aecnoc a ee\n\nond bya vera the ats wer subjected to 8 no\nrnin fr aasnoee poche the ssa\nocedure as permed aan te fat surge. Th akin\nches we removed and the csaecton and hiclza\nen of theft stress hac acorn to precusly\nMacated orcomtwen", "ihe Enel enestorncels prresskilty feet wee paricemed using\ncst sation tothe blood vest anastomasia ana direc\nsbematon of presanes floc fi, beng expected pdsaing\nbleeding of the artery in question.", "enn et reid SOC! Pe a ee\n2 aeralanastrona was asacted, Thelumen fhe vaccar\ngrrens wasiigated with a 10% famaldehyd sluten wih\n sythge and alco cahet. The animals, si anesthetized,\nsere euthanized by esraveneus lethal necton, flown the\n1909 recommendations of Calgio rasibio de Experimenta\n- Anil (COBEA). The vascular segments were anchored 0\nsna pide of syne foam by is edges usng mcrosugcal\n‘ation icitaer th ancid anual Gumsnoncr,", "3 um in the longitudinal plane of the vessels. Each sample was\nsaluted by tee saning methods: hematoayi-cosn (HE)\n\nMasson strchrome, and Varo. The ees wer bd wxam-\nned bythe sane pathologist ina conventonal optical Zas5\"\nrietoseope using 0-200 fold augmentation. The pethvasca-\nfr olammaton ae ranked n ach sample aa abaert, mid\n\nederateoilense Furthermore, samples are assessed ot\nhe prosence of anourysm or trombus. Al ses wore bind\nevaluated by an experienced pathologist", "ihe vessels Segments were sent to the Anatomopathological\nSenice. Aller proper processing, the surgical specimens were\necirertiner| speed -yenannls duvten matinee feats", "The Laboratory of Medion! investigation of the Musculcshetsiel\nSystm of Faculdade de Medlcna da Universidade 6 530\nPaulo, wih fa funds. hae borne the resources to cay out he\nsecenenry eseeeLrek.", "For chassolestzstion of te quasiteive cise cescspive state.\nios of parameters measured was pafomed: mean, standard\nsoviet, piviauey orci tanheaee eahua:", "TO compare the test results regarding the Instological analysis\nanatomical parts, vided in specie classes, he Pearson's\n“hi-equare test was employed.", "The normality test for weeght, length af surgery, number of\nnodes and bleeding weight was the Kolmogorov Smimova test.", "in all cases we adopted 5% significance level (a=0.05).", "Tn sere Te CS one coer Ee ee\nhe tree greups analyzed, namely Merosute®, Pyuture®\n2nd Ethicon\" groups, confming the pating of the groups.\nThee was ono sgnificant ference betwoen the quanti\nstiches of ter’ anastomoses sutra aac of he hee\nsoups analyzed.", "Te EE Me ee Oe eos es Se eee ee\n3736 min, on average nthe Merosutze® group, 3240 min ny\nna Pluie rcup aed 326 min the Eicon” group The\nference betas values was eatealy signa fp = 005)\nriven cormparing the Micossture®greup wi the Psat\nsoup, te later showing a lover surgical time. There was ro\nsny'tsuat marorite boubeaaa Sra ehior vai (ukie 1)", "The bisecting cooured is each paoceduse, Quaniled a8 pre-\nius described, was higher in the Mcrosuize™ group as\ncompared to Poyutur® and Ethicon? groupe, wth no ie-\nsca beieoen ¥s beat ee. CRIs =", "Histological enalyels were renhed es abeert, mid, snoderste OF\nefense in each sar, except forthe dichelomzed variables\nlysis such a thrombus and aneuryr, which wera sch\nminated as present or abeent.", "Lcrrachaeistedbersiochaletet ele tadketsctace bert lschradiniaiec ul\nmatory procaes among the tives groupe anakyzad.", "", "", "", "RESULTS" ]

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[ 17567.396982799954, 48774.15977551858, 32254.997612918727, 18665.014565074118, 10373.622580180876, 25680.534115341958, 25541.207780639175, 8783.72786617896, 9890.2215151391, 7835.937368347193, 7295.300546331098, 5834.295740245143, 2711.674240743683, 15562.09502579947, 20308.25518919062, 10489.345873792889, 10201.753763495013, 5248.349887226475, 1897.5815232000314, 453.1676133599831, 21825.77965045988, 429.2941445100005 ]

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[ "oot ey ana le ed Sec leseer ee ean [alata] eves Va, Lise Eun En Se ere eee\ncreases, One such assolton fests multvatate distance mak regression (MDM), We explore some ofthe fete\n2 IDNR using Genetic Anas Werlshop 17 simultd data i search of potential improvements in dtance\nmeasures We used genotype data fom 687 unrelated inva, in 200 replatons to test the power of MDM 10\ndetec 12 rat QD causative genes bared onthe Eucidean distance metric We ako estimated the fae postive rate of\nMOMR use 508 canol genes In aditon, we compared MOM with Mantes est and cling anal fr rate\nvatiants. MDMA performed comparably well even with the Euclidean distance meature.", "High theoughpet sequencing techaelogy slows ientilice\non of new ear alleles in human population, but the\nparseness of these allele in samples becomes a por\nant obstacle to detecting the ue elects af are variants\nunder a single varant-based paradigm. The increasing\nnumber of Mentied genetic variant also requires nace\nait ests, thereby aggravating the sue of lw sai\nical power. Several methods, based on collapsing\nouping rte variants, have been developed to alleviate\nhs problem However, these methods arbitrarily define\ncommon and rae variant and treat them differently fo\naly. This artificial catifieation may fl to eaptue\nportant biological reality. For example, st has been\nown that a common variant can act asa node ofa\nae vila fet 12) Te quite posible that collapsing\nmultiple rare variants may dilute the true genetic effect.", "aggregmtes each geastic warinat's information to build «\ndistance matrix. For this reason, once an appropriate\ntance mati is asuened, the sues of enlipletsig\nand sparsenes of data become less cic for MDM\nThe most crcl problem ia MDM i how to define\ndistance metic for summarizing genetic diferences\npetween individuals in elation to thei influence on\nrai(s) of diseases). Dieent distance measures can be\nused: one of them isthe Fuldean distance, Sima\npaved ansciation txts such as MDM can be a8 power\nfal as some trnditional tests of astocation when com\nmon variations ae involved [. However, the uty of\nhese methods for rare variant analyse i not wel\nunderstood and needs to be interrogated [5]", "(Miultivariate distance matrix regression (iis) can\nprovide a flexible platform fr a phenotypic association\nest of DNA sequence [3]. In ths method, for a regon\nAINA sequence, genotype dsm between ind\nviduals are associated with phenotype dissimilarities.\nMIMI thee mk talk 0 ocala went oot laiend", "nS ee ae ee ee eee eee\nmodel [36.7] defined in matrix notation an", "where ¥ Is on ox p date suntrix, in which 0 is the\nnumberof subjects and p i the sumer of unknown\npologallyeelevant genetic vatables; and X isa\nmodel matex, in which mis the number of predictor\nvariables. ls an m x p matrix of beta coefficients and t", "inhentty Schone of bheicen 9t Cads MES QUIIOL LA", "Doyoung Chung , Qunyuan Zhang, Aldi T Kraja, Ingrid B Borecki, Michael A Province", "Distance-based phenotypic association analysis of\nDNA sequence data", "Abstract", "Background", "Methods", "Multivariate distance matrix regression" ]

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[ 36329.772663623095, 44310.56280656252, 38341.96978319902, 16419.60516206757, 4683.5309725583065, 13850.876320094336, 3271.5679785269895, 4434.225239424501, 17873.517708204134, 451.392730978936, 649.6004365690314, 471.2858401166741, 1627.3869130733074 ]

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[ "ally restored to a healthy level. The problem is that few\naients are able to maintain their new higher weight: in\ntad, alarge proportion relapse [3-7] and asareslt dur\nng the first year following discharge 30-50% of patients\nneed tbe rchosptalized [8-10]. This fure to maintain\nhe changes achieved in hospital has led to interest in de\nveloping post-hosptaization means of preventing the\nJeteriration that follows discharge. An initial report\nsuggested that uoxstine might have this effec [1], but\nhis was not confirmed in a subsequent controlled til\n7]. Theres preliminary evidence tht form of cognitive\nbehaviour therapy (CBT) might be beneficial [12,13] but\nhhis remains to be substantiated.", "In the present study we adopted a different strategy.\nthis was to modify the inpatient aspect of treatment, the\ngoal being to reduce patients’ propensity to relapse on\nlischarge. To this end, the usual eclectic approach to in-\natient treatment was feplaced with a programme based\non’enhanced' cognitive behaviour therapy fr eating dis\norders (CBT-E) [14] as this form of treatment is explic\ntly designed to produce enduring change. To this end, i\nfocuses both on modifying the mechanisms thought to\nerpetuate eating disorder psychopathology [15] and on\ndeveloping personalized relapse prevention skill [16\nthe treatment hasbeen found in two independent studies\n(combined n = 245) to produce sustained change in those\nating disorder patients who are not significantly under\neight, thats, those with bulimia nervosa or eating ds\norder not otherwise specified (17, 18]. thas aso been\nown tobe associated witha well maintained and good\nputcome in two cohorts of adults with anorexia nervosa\n(otal n= 99) [19] aswell asa cohort of adolescents (n =\n46) (20.", "There are two forms of CBT-E, a focused form (CBT:\nED) that targets eating disorder psychopathology exclu\nively, and a more complex broad form (CBT-Eb) that\nso addresses certain additional problems (1, mood in\nlerance, clinical perfectionism, low self-esteem, and in\nerpersonal dificultis) that in some patients appear to\nmaintain the eating disorder psychopathology [15,21\nAn outpatient study of CBT-E with patients who were not\nundereight (Le, those with bulimia nervosa or eating\nlisorder not otherwise specified) found that in those with\nsubstantial addtional psychopathology of the type tar\nsted in CBT-Eb, ths version of was more effective than\nhe focused form, whereas in the remaining patients the\nopposite was the case [18], although overall the two treat\nments were equally effective. To date, no data are aval\nsleon the relative effect ofthese two forms of CBT-Ein\nthe treatment of patients with anorexia nervosa.", "The present study was designed to address three key\nclinical questions and to compare the effects of the two\nCiT-E inpatient programmes, The thee questions were:\n(1) Among patients with marked anorexia nervosa, what\nproportion is able to complete inpatient CBT-E? (2)\nAmong those patents who ean complete the treatment,\nwhat is their outcome? (3) Are the changes sustained?", "Arendemined conteolied tal was conducted at on cating dis-\nrnp unt Hl pans were ano snp 0\neto popaines inp CHT ornate CBT EP.\n\nsn were ceed ele ests ae he endo teat\n\n6 and 12 month ler. The prod of erpalaton sed\nwes thet 19 wk ing on a nae as adhe\nvnning 7 ang ay pat Ti alc coma a\nonal Heb Unt? Raseng ppovel testy Sty Pro\n\nx No, aie Un spovedS01205) ad al perpen\n(or tepals Lr pests user 8) av we\n\nrnd content parca the anon nt pe\n\naan hi", "‘The sample wos recruited Sem consecative selberals to ths ost\ning does inpatient uit Vila Garda Hemp (Nortbern ts)\n\nris source of he eer was betarogencot, Minced Ely\nJct and econdary cre helt professionals, ating dae\n\nler specialists, outpatient eating dardr nis of the Nana\naan Health Sem. general pubis and ace internal\nmedicine wit) Paints had tobe aged etmeen abd 6 years\n\nfall the DSM-IV dngontierei for anoreia ery [2] 2\naged bath bythe elering diniian sdb an eng dnorder sp\n\nnt (RDG. and wo regu inpatient restment her are\nfare of oupaten trestment or Heusen order\nld ot be anaged lyon an cute at. Eighty-one er\n\n8099} of theeiblepatiens accepted estmentandwere\nedt the its wating lt of up ot wen Dung the pred\nba the wings the paints ere nage by the lrg age\n\nFe erent (5199) a the cll atin were exladd for the\nlowing resans (an acte psychotic stem = 2: sigan\nbane abun. n= 3), whe 1% (149) declined to pata\n\nPipe L ahowr the flow of participects through the ato.", "The two inpatient CBT-E programas wore decived thems\nctpatint based CBT-E Both were deiged to ensures wie,\nle than edertic opproach to he ptt apt teatro\n[14 The programs rtcined al he mn sabe aod proce\nJures of CBI E These were provided in both individ CBT E\nlived sod ina grouptarnal However, th progres ied\nom outpatient CBT ip that there was asstance wih eting\nhe euly weks of haspitalzaton Tha was provided dens\nDetails ofthe prograttmes are provided eleeeehere [23°25].", "CBT-E includes many strategies and procedures designed to\nsa i the he ie fas and Procedures deaine", "Method", "Design", "", "" ]

[ [ 42.52, 60.27, 293.76, 228.11 ], [ 42.52, 226.03, 293.76, 483.12 ], [ 42.52, 481.03, 293.76, 699.87 ], [ 304.02, 60.27, 555.26, 151.61 ], [ 304.02, 209.02, 554.92, 338.56 ], [ 304.02, 357.55, 554.89, 561.36 ], [ 304.02, 580.36, 554.92, 678.07 ], [ 304.02, 675.85, 554.92, 699.28 ], [ 316.77, 177.09, 354.42999999999995, 189.48000000000002 ], [ 316.77, 198.29, 344.9, 211.23 ], [ 316.77, 346.82, 366.27, 359.76 ], [ 316.77, 569.62, 366.11, 582.5600000000001 ] ]

[ 40692.07346319524, 61558.874020436546, 54095.111686348915, 22597.432165330043, 30028.264480635058, 50524.7240998745, 24085.653023724444, 5719.4369496500585, 466.5702300000121, 363.9798925500072, 640.538725499995, 638.4490769999684 ]

[ 1, 1, 1, 1, 1, 1, 1, 1, 2, 2, 2, 2 ]

[ "ts equivalent in D. melanogaster (Figure 6, Figure 7A,\nAdditional fe 4: Table $4) In fet, stapes 3-6 are In\nally located more than one stripe’ width more poster\nor than thelr D. melanogaster counterparts (Figure 7A).", "As reported for eve mRNA [54,55], each Eve protein\nstripe la located more posteriorly in C. albipunctata than", "Figure @ Comparison of quantitative Eve protein expression pattems between Clogs aftipunctats and’ Drosaphile melanogaster.\nipecenatve ere Mage ching Ee pte eypesacn naga pet landcare Yon! el eae ft\nche crn Cando 8 Lt ive eta lek onal phe gop ton caer tates age\npon paso te is Coburn dene shown Bick Dre ane esi ee el se\nmia nang fo st vor aes epee ae ptr) aban part ere he ep Te\nrctze pte compan exon snc apa wen ed ht Pach pes ten pe iy", "EmE or\nWAN | UA", "npaincta ss shut\n—\nane Eve\n‘NB er\nsite sriorly over" ]

[ [ 304.72, 688.5, 538.57, 735.44 ], [ 56.69, 712.49, 290.57, 735.44 ], [ 62.7, 587.41, 526.72, 656.49 ], [ 56.69, 90.33, 538.5799999999999, 582.82 ], [ 56.69, 688.52, 267.22, 710.99 ] ]

[ 10975.517053584568, 5365.282709083287, 28059.898832275067, 237326.47738800006, 3159.845287441509 ]

[ 1, 1, 1, 5, 2 ]

[ "members, practitioners and cessaschers, while \"What dees\nhe future hold for autistic adults” was autistic adults\nhird most frequently endorsed question.", "Satiefaction with she ;patiem of current funding. Tn Ge second\npan ofthe survey, participants Were asked how saistod\nbey were with the patem of cutest funding for UK\ntam rescarch (See Figure 1). The mode response fo all\ntakoholdr groups was disasfied (score of 2). Analysis\nof mean ratings showed tht researchers’ ratings were sig\ntical higher electing greater satisfaction, M~ 2-3\n\nSD ~ 0.91) than autistic alts (M = 211; SD = 0.88) and\namily members (M = 2.19; SD = 093) (both ps < 001)\nput not prctioness(M=2.28;SD =0394), Whon asked a\nvat extent they thought this pattem mapped onto thei\ntated procs, the mode response for autistic ads\namily members and pacioners was ‘ot realy (Sore\nof 4) and for researches, “somewhat (sore of 3). Thete\nvgs main effet of aroup, £13, 1812) = 5.24, p= 0.001,\nNy O01; researches ratings were significanly lower\nbeter ligament with ei pics) (M~ 3.39: SD =\n) $9) tan ats adults (M ~ 3.84 SD = 0.94), family\nembers (M = 3.68, SD = 0.90) and pacionees (M =\n3.66; SD = 0.85) (all ps < 0.02),", "services (1) to support individuals at Key trensision points,\nparicully from secondary schol to aul services (2) 0\nsss individuals and Tailies post-iagnosis and (3) 1\nsecinict uetiotie perpls inte euachomment teoe'Tikde di.", "Open questions. Survey seepondents wore also asked te\nvide dts on the one topic of esearch hat they would\nike to be researched inthe coming decade (a of 1238\nsponses) summary ofthe resin themes and cote\nponding quots is presented in Table 4. Thre were may\nomman themes among slaksholdrs, with respondents\njocusing largely on esearch Hat would make a diference\no hee everyay lives. Among the eight emergent themes\nsee Table 4), family members and practisonesstssed\nhe need o develop effective ways of teaching lie sll o\ndividuals with autism and of promoting independence in\nsdalthood. There were also eal, partially fom autistic\ndls, but also fom other community members for\nseu on services, with many respondents expesing 3\ngeneral dissatisfaction with the serves currently aval\nlet thom. Certain groups nevertheless emphasised dis\nst teves ur eorvinen tect eo doen", "Family members and pmctidioness futher emphasioed\nthe need for more research on bow eilfen ad young\npeople with stim shin and ear, which could lead 1\nbeter inervertions inside and outside the classroom,\n\nMany aust peopl, funy members and researcher\nsocalled for more rexearch into co-ocurring conditions.\n\nAuris people and esearhers wasted beter undestand\n\ning of Sensory soasiivides, anxiety and depression, while\nfamily members highlighted the ned to understand co\n\nsccuting medical conditions (eg. gaswoistestinl\nrable)", "Al stakeholder gooupe celled Sor research on under-\nsanding the place of eutistie people in society cher wih\ngad to bow \"newosypical society\" might change to bet\n\ner accommodate autistic people eluding celebrating\nference) ater than ceearh targeted towards det\n\ning “cues or “prevention” of auam orto the need for\nesearch torase more accurate awareness of autism among\nthe general populations, especially in public services.", "Family members, practitioners and sessaschers — but\nnt autistic adults ~ aso prised treatments and inter\nventions for ats chien, young people and adults,\nhough particular weauments were rately. speciiod\nLifespan issues were identified by autistic als, peat\nionors and researches, highlighting the aced far mose\nseach on asic adults, paiculaly older adult.\nFinally, autistic adults, family members and peacitoners\ndetifed the lack of knowledge of gender difevences in", "This study investigated the views and pesspectives of the\nUK's autism community on the ature ofthe research\ncutenily conducted ad prioiies for future research.\nThe sess fom the focus grouptinterviews and the\nlarge-scale survey clearly suggest that mombets of the\nUK autism community are generally dissatisfied by the", "Table 3. Top three research questions endorsed by each stakeholder group.", "Autistic adults (0 = 122) Family members (n= 649) Practitioners (n = 426) [Researchers (n = 120)\nste peop! (61) site poop! (61) este peop (480) este peop? (650)\nteimprovethe ese of bait nanethe andes thkandlnn? (8). ‘hk sn ar? 2)\nsine peop (3%) su peop! 3%)\nforsee si? (9%) thekenaleaen (5), bermecrtha needs of bentnecthe nee of\n\nsuustc people! G70) uostc people (51%)", "Discussion" ]

[ [ 49.61, 226.5, 284.78, 261.57 ], [ 49.61, 274.28, 284.79, 513.5699999999999 ], [ 300.26, 226.5, 535.41, 273.57 ], [ 49.61, 526.37, 284.79, 729.5699999999999 ], [ 300.26, 274.5, 535.44, 405.57 ], [ 300.26, 406.5, 535.45, 501.57 ], [ 300.26, 502.5, 535.43, 621.5699999999999 ], [ 300.26, 658.5, 535.44, 729.5699999999999 ], [ 49.61, 69.04, 334.22, 79.56 ], [ 49.61, 83.55, 532.92, 205.55 ], [ 300.26, 638.26, 358.88, 652.41 ] ]

[ 7368.531900000031, 54950.85234915279, 10855.741200000048, 47687.8253928693, 28307.573999999557, 21855.515399999917, 25319.140499999747, 16711.9347000001, 2993.3138423337587, 58963.46620000001, 829.3557600000058 ]

[ 1, 1, 1, 1, 1, 1, 1, 1, 1, 4, 2 ]

[ "RMS can also provide time-resolved 2D spectral maps of the EBs and is able to detect\nhe increase inthe numberof CMs dung differentiation, Starting with day 7, the spec\nral maps show the appearance of CMS inthe beating EBS, whe no relative increase in\nhe PCI scores was detected in the non-beting EBs. twas so found thatthe areas of\nhgh PCI scores alo matched the regions ofthe EBs where the being was most pro\nnounced, as well as the expression of «-actnin obtained by immuno-Auorescence ln\nwing atthe end of the time-course experiments [65]. These recent studs show the\npotential of RMS for non-invasive monitoring of stem cll diflerentiation, which may\nenable a more efficient optimization of the relevant bloprocesses.", "This paper reviews recent applications of Raman micro-spectroscopy for time- and\nTyuilalipineatied, ruslocsiac’Smsateie OF deems calls ducing @itieeendiotion tation Ee", "lard pchadhnohalda hare Heron renin adenine einitale ital\nppeasten of human embryonic ome A ear ara enemas ot\ntree tg wa oa\n\nrand Gis gown candace show eesion cfc mai cacti —", "A\nll lee «| owale|\n\nraced tgp © stmmpiinnoves Sennett\n8\ng\n: 1\nEEA\n: Day 5 Day6 Day7 Day 8 Day 9 Day 10", "Conclusion" ]

[ [ 117.64, 544.29, 477.71, 668.43 ], [ 117.64, 711.14, 477.61, 736.17 ], [ 123.65, 472.48, 467.45000000000005, 521.62 ], [ 117.64, 90.33, 477.64, 467.77 ], [ 117.64, 695.86, 168, 707.65 ] ]

[ 43256.7167169177, 9010.892652855604, 15285.3059180798, 135876.7749474657, 593.8817414499936 ]

[ 1, 1, 1, 5, 2 ]

[ "ey, eee eee ee ee ee ee\nhich defines the eemetto SBMNH ear (UNFPA 20\nrich canbe cd bs fo renting agement (a\nce for mvs wich ay poe theaavert() Howe\nJolanda (13, 200 WHO, 2010) a are ae one\nrc womens tifa, ante do oo Se", "ee\ntht SRMENIC workforce (USP cl 2010), he way i which\nsna ey need lof ar cde wi\nhertra compan hich uel os pacino he\nhr ae pip ln ns i is Pet\nats argsnts between there bro etme (082\nfn ol Supper and Ue 2017) Hven ander the heigl\nmidvleled ca there a vty of mode cading cane\nam community bse and fy based mien (Seal 2\n\n1g), Bae on wien of he ey of mide ed ear (Sn\n2) he MSF adortes a midveed model ih os\nit iting al interaton of these eres ath he rea\nSee,", "ee eee\nesi hy tn we\nives need (02) e005), earn nin tht he\nraphe and puemilogial condone (cn Hoo eae ot 2\n7), Reference halal be mae aise bl sandr\nSp eiien hentia caehaen OA Eoin Mine", "sen nda to pve highly and reset ere, a\nhc workers ar tated asf, calahrsve ad spp\nwrk emioment. Daring thi agenda ge th", "ee en\nfewlopment steps I and 2) stakes are asked to define what\nseve inplometatin wold oak, a sed ome ei\nison ine dt ed lk\nspplemensatins This Teas fo ths selection of rueausy indicators te", "Pag. 3. “tages of exipermensioteon of the [St Stidwetery Services Pramewor’.", "Preparatory Steps Service Development Modules", "caeckial ts har minaiehd eee ual uae bedees", "————", "Serence development step 4: Tesi, monitor, evaluate and adapt\naan eee" ]

[ [ 37.59, 410.12, 288.69, 503.08 ], [ 37.59, 570.73, 288.70000000000005, 747.08 ], [ 306.59, 441.75, 557.68, 565.83 ], [ 306.59, 567.08, 557.67, 639.08 ], [ 306.59, 685.81, 557.68, 747.0899999999999 ], [ 186.75, 390.54, 408.53, 397.74 ], [ 81.64, 57.11, 513.64, 383.83000000000004 ], [ 37.59, 539.32, 287.72, 558.8100000000001 ], [ 306.59, 410.4, 546.25, 429.83 ], [ 306.59, 654.4, 535.45, 673.8299999999999 ] ]

[ 23099.782559338957, 42065.39636492077, 30629.561529377475, 16749.419168902095, 15255.85818522377, 1596.4721293920884, 141143.472, 4549.594699465495, 2991.339558667387, 2773.1167251596926 ]

[ 1, 1, 1, 1, 1, 1, 5, 2, 2, 2 ]

[ "Bee pA ae Meh nearer f Anes Regent cae SePOne\nng (actions atthe start and end ofthe epidemic. Again\nhe multinomial dstabution with q, a calculated fom\nhe logis function is used to azsgn the misting case\n0 days ofthe epidemle. Figure 4 illustrates the sim\nated outbreaks.", "panclernig Feaimn Tie Te iene by randomly eae\nrom allo the IL eases using a binomial distribution\nwith probability 0.25, 0.50 oF 1.75, indicating that 25%,\n50% ve 75% of vases, respectively, are pHINI", "Finally we consider the possibility that a significant frac:\non ofthe cases were not actually pandemic ifluenea\ntrain and, infact, cates were overreported. We stl\nsume that there was an overall underreporting of\naluenza like illness (IL) according tothe schemes\nJescebed above. However, we addiuonally assume tha\niy 4 Sarton af thas cones axe Sdaod Of fs", "Fon the, ALE anenyeen, We, calcelane, tnt: Penne’ OF Mp\nandthe serial interval, asuming the sell interval fol\n\nows a enltinomal witha masta length of four day\n13} We estimate the parameters under two scenarios\nFist we consider the fst 16 days when the epidemic\ncurve isin exponential growth and 326 cases had been\nnbseved. We perform estimation assuming an infinite\nnumber of suscepuble individual. Second, we consider\nhe entie epidemic curve and estimate the elective\nreproductive number R,, by allowing R, to following a", "hignwi#t_2W“« ee", "AR=30%\n8 a\nze ze\ng g\n3 a?\n28 28\nrare cs eae\nsy ey\nanest% ansse%,\n23 ge\ni i ;\nBe Be\ni r g\n28 q z2&8 w\nos mms os nem ws\n“ dey", "Overreporting" ]

[ [ 56.69, 87.89, 290.53999999999996, 158.57999999999998 ], [ 304.73, 87.89, 538.65, 134.65 ], [ 56.69, 171.57, 290.58, 254.22 ], [ 304.72, 135.18, 538.6500000000001, 255.01 ], [ 62.93, 706.87, 532.36, 725.93 ], [ 56.69, 273.44, 538.5799999999999, 706.3199999999999 ], [ 56.69, 159.71, 110.36, 170.02 ] ]

[ 14504.28583306531, 10400.489168367698, 19326.988689157122, 27922.683972231578, 5874.447209491278, 208598.61564, 553.4340989669981 ]

[ 1, 1, 1, 1, 1, 5, 2 ]

[ "form carbon-centred’ radicals with subsequent propaga-\nion of peroxyl radials. These lipid peroxidation peo\nts raul in membrane dagenersion as wel as pre\nand genome toxey [56], culminating in aging and\nieath (Figure 5).", "ee a a a oe\nas at hats stceneen chart Reed icin", "eae eS eee\npropose the homecscouslangevity adaption hypoth\ninary, thatthe lower dees of fay acid unset\nton in longevusanirals decreases thet sentry to\nip. peroxidation and inacromnolecular damage. ‘They\npve since publahed two indices, which they suggest\nsussvely correlate with espn: the double band index\n13), later refined to the proxsdaton index (1) (57. Bosh\nces describe the sak of oxidation of unsaturated fate,\nhe explanation again being that lower Pleads to ess pi\nand dowastzeam protein and DNA oxidative damage ad\nheefoe leads to espan extension. Valencak as reel\nindependently found that for isolated mitochondria of", "Tlowever, We Wish Lo polft OUF several caveats with\nsing PI to explain aging and longevity cata. Fal,\nPI does no take into accu that saturated fatty acid\nai under certain conditins be more susceptible to ax\njain than unsaturated fatty acids, especialy some\nshorter chained fats [58] Secondly, Pt largely eelleets the\nsntent of one very highly unsaturated PUFA, DHA. I\nled, DHA is relly the predominant PUFA that hs\npeen linked with MLSP [14.2749] ierespective of to\nPUFA levels, which appear not to vary with espa [1]\ngute 4). Third, molecules other than lpi peroxides\nay ulimately be more important in mediating cella\ndative damage. For example, research in huraas and\nial models reveals that the aldehyde pid peroxide\nion products, 4-hydroxy-2-nonenal and malonadehyde\n(MDA), are more stable than lipid peroxyl radicals and", "SS SR Oe eee Eee ee Se reas ee ee ee ee en ee ee en ee ee\nforested tym (6) Presta ays (0) cour The tte apa Sia fe by oc\ntere dad Tae? Teed he ot unsere ttc sa ait nie an fo OA, ochre lA\nsean bans quclmasedaed recedes sandnaane ronan parnaetel Hedge", "B\na z ~\ni ds\nae i:\nis 2\nso J © Pelee\n“rr thy t\n2 ees\n>\n° 2”\ni {>\nie ps\nqt, fE\npee re,\ni: iB\n| ° i o a OM\ni taledid sum ltfeapen tyears)" ]

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[ "Separate chambers were used for NH; and NOOO);\nlux measurements to avoid potential effects of NH, fit\nraps an NO or CO, 2s well a 0 allow independen\nchamber closure times. Using thee replicate chambers\npe treatment, this gave a toa of 1 chamber anchors\nrine under each rof with tealments arranged in Latin\nsare designs. Gas ux measurements were dane a\n1a 14. 71,20 37 44 ames DA", "erennaphalte pnetnbatd. sanmnetaah-sandebenapiys\noftware\\v. 00; Development Coce Team 2013). Fos\nparametric tests, the assumption of normal dstrbuton\nof within group eros was tested by the Kolmogorov\nSmimov test, while homoscedastcty was checkee\nising Levene's test. When analysis of vatiance yelde\n+ sigiticanteflct of the factor ‘tesidue placemat,\ncomparisons among the tee amendment treatment\nwere performed using Tukey's HSD test.Also, compa\n‘ns betweenthe conta andthe combined mean ofthe\namended treatments were dane using linear contrast\ncontol +10, mix ~0'5, mulch -0'5). Emission facto\nor esidues were compared using Welch's two-sample\ntest. Unless tated therwise, results are presented\nmean 21 standard enor ofthe mean (SE ML). Statistica\nSignificance was stated at P< 0-05.", "(until 1 August}, soll matsture tended to be lower with\n014 fin. 0°12, max. 0-18) rll WPS (n= 325) a\ncompared to 019 (min. 0-14, max. 0:25) min WEPS\n(n= 1200 in the remaining period, This was a result\nvery high sil temperatures and lower inigation rates\nFig, 1a). Note that there was 2 gap in soil moisture\ndata during the ist week after resiue application du\n0a data logger flue, Teavads the end ofthe exper\niment wer iigation rates were necessary to ke\nmoisture roughly constant, due to gradually decreasing\nemperatures ig 1a). The median wind speed was 02\nms al th relative frequency of wind speeds overtime\nwa 0:17, 0:35, 029 and 0-19 for the intervals 0-0-1,\n\n1-02, 02-03 and 03-20ms, respectively (a=\n1633, hourly recordings to an accuracy of 20:1 mi\ndata nat shown).", "The brigetion pan etaing te eaperiment wee 12> ma\nwith daily amounts of O-4 mm, which kept the si\nmoisture a an average (9 =1525) of O18 in. 0-12,\nmax. 025) and 021 (min. 0:18, max. 023) mlm\nwaterfiled pore space (WEPS| ata sil depth of 0.05\nand 0-15 m, respectively (ig, 1a). These values cone\nsponded to volumetric water contents per ttl si\nvolume of €-088 and 0.091 ml and were derive\nising average sil porosities according to undisturbec\ncil coesaturation measurements. These water contents\ncanbe regarded 25 high and approximately etc the\noils eld capacity. The field eapacity was not deter\nmined. However, water contents at time of installing\nhe 00 (10 July 2012; Fig. 1a dl not exceed wate\ncontents during the experimental perio, even though\nprecipitation summed up to 75 mm within 2 weeks\nreore nstallng the oo. This suggests afield capaci\nof approximately 0-10 mliml relating 10 sol tt\nvolume. During the first 3 weeks of the experiment", "lace |-8 Chamber Chasing mes me too long fr\nunbiased measurement of sol respiration, the emis\nson values presented should only be interpreted 3\n1 relative proxy of soil_microbial activity anc\ndynamics of residue mineralization,", "Denar ike app ecenen Oy cea nawer reeraees i Wen\ns thoughout the experiment in the contol treatment\nCO, emisin rates were Renerally lw and did ns\nexceed tes of 30mg CO, Cth Fig 1) Aer he\npplication of cauliflower resides, the emision rate\nCO; increased immediately with highest rt\nabuered 1 day after application, fled by a sharp\ndecreas and approaching the te ofthe conta eat\nment 4 weeks later (Fig 1b. The cumulative CO,\ncisions of the three amendment Westmont\nTable 1) were sigticanly (test P0001 dere\nathe early period (Tukey's HSD txt mix > mulch >\ncont) butt in helt peri Fest: P = 000)\nThis difleence was lso apparent inthe EFS, which\niicated that 301 and 16mg CO; Ciy residue\nhad ben respted to CO, dring the eatly peso in\nhe mix and mulch treatment respectively (Welch\nTwo Sample est P'=04036; Table 1). According\nnear contrast, the cumulative essons of he con\npine amended esments were signal highs\nhan thse ofthe contol treatment the ealy (Pe\n01) an ate (P= 042) pera as wel over he\ntal dation (?<0.001) ofthe experiment No sig\ncant iferences occurred between max and mulch\neaten’ in emsion sus Tukey's HSD tes)\nEFRe Welch Two Sample f tes), ether i the ht\nveriod or over the whalt experimental period.", "Statistics", "RESULTS", "Abiotic conditions", "Carbon dioxide emissions" ]

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[ 1, 1, 1, 1, 1, 1, 2, 2, 2, 2 ]

[ "Figure S Oral virls shedding of falcons during WHY lineage | challenge. The oral rus shedding of faicans during challenge is splayed.\noe thal le (tac fsa fe grap ean In Borne gts tcc fhe hicks peat he mn\nerainry sues pe) Cue epee ad wend Th ne ooh aes oe a\nrote mane sch tap bey ered sinh he re acon gaps wah sac upnare ace\nrl nla gre hd cmutan ta ape ae tld wh sn se UIA cal ening Son peas cae\ni ee wate gras the Steal sgn lees nce al Wal gome ong eed ca a\n226) There was no group wrth a satay sinfcant ference in dua", "Figure 6 Cloacal virus shedding of falcons duaing WAY Hneage } challenge. The cloacal ius sheding of cons duting challenge is\nses Cee teil wes lot of vas bal gous thon borne’ she ei fhe ae epee he\nrina manana pec te pete Sart arent Te bo eerste sot\ntoh gop nd rau eth up teenie me mci Vaan gap th satay apnea Stowe ee\ni ofc ed roe sung msmpatan ogoupe ae bens ihn srk ANOVA oe al arg ap puro\n\n8 Tee oS hs ty scan fence ston of aa al eae rg feed caer a wth\nrt erent coneenenaen", "", "" ]

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[ 1, 1, 5, 5 ]

[ "that dillerent genetic backgrounds might modulate the\nets ofthe QTL fr example de to varying numbers\nnfother modi QT. and/or epsaie interactions with\nnde QTL) Alternately, the vation ia elfet se\ncould reflect diferent underlying genetic buses in the\nlifferent freshwater populations.", "UN second unexplained feature of gi faker reduction\nserved inthe study i the modularity of dorsal and\nrental gl kets: both the chromovome 4 and 20 QT\npave much stronger eats on vena gil raker ube\nan dora gil ker number in all thee crosses. In an\nnthe ess, we peenousy also found extensive modular\nty along the dorsa-venral xis inthe gente contol of\nikleack gil rakerredtion (89. In the time cours\nstudies presented here, ventral gill rkers form much\nraler during development than doral gill rakers, 0\nhs modulanty might rellet dhe temporal window\nJvelopmentl elect forthe QTL, andor regionally re\ntected (lor example, in Yenzal not dorsal peimorda\npression of genes underying the QTL Regards ofthe\nJevelopmenal genetic mechanism, this song modula\nfll rakes even within row 1 suggests that sepaatly\nphenotyping dorsal and vental cow 1 gil ers might\neld diferente esults than suroning the total ofall row\n| rakers, sis commonly done in ecological and evolu\nonary studies", "A hed unexplained’ genetic feature of gi faker reduc:\nson observed inthis study i that one feshwate popu\nson (FTC) is moce faker reduced than the others (BEPA\nsnd PAXB). Interestingly, much a this derences duet\nich stronger seduction of ETC in ow 1 gil ake se\nve to other rows (compare Additional fe 4: gure $3 to\nFigure IC), which might eefleet difrences in freshwater\nits andr avalable genetic variation, Future work using\ngenome-wide Unkage mapping in nulipe F2 crass wil\nsddress the extent of genetic consent, and. whether\nsmaller effet mower QTL are also repeatedly used 1\ncompl repeated gl ker reduction. We hypthes\nat there are additonal and/or stronger elect QTL co\nrollog FTC gil ker than in PAXB or BEPA, possibly\nchiding modular row L-specie gil raker QTL presen\nFIC Ia addition, farther genotyping af the como\nome 4 and 20 QTL inthe tte crosses, we uly 1\nchange the main result presented here of overlapping\nTIT, masy Sieuecwe ac relation of Giece OTL,", "Known about the Cevelopmental processes altered ®y\nhese evolved genetic changes. Here, we find tha gi\nker spacing i increased i all thee freshwater popula\n\nions i adults and dense developmental me courses i\nwo of these populations reveal an early development\nnerease in the spacing of gill eakerpeimorda thats\ncontrolled by the chromosome 4 and 20 QTL. The adult\nlllerence i pattern is specie a8 an increased distance\nptween the budding gil raker peimorda ata surpis\n\nnly eal tage - belore hatching eakeroaication, and\nsing. A previous study found no significant plastic\neaponse in gil raker number to sits in diet (82). This\naut, together with aur findings that marine freshwater\nil aker umber ferences are fed before the onset\nCeding suggests that gl raker number te largely ge\nically haed-wied at an early stage in development\nThis genetically programmed difference in spacing ale\nsomewhere upstzeam ofthe gente regulatory networks\nontolingeaty spacing of Fetadplasin receptor (Eder)\n\napeesng raker primordia although the preci lection\nofthe evaved changes in ths pathway in diferent fresh\n\nwater populations eens to be determined. A comple\n\nmentary expression pattern of Edar and Eda in gl ake\npuds and intraker domains, respectively (9, this work\nsemble the complementary expression patterns of Eda\nund Eda is other epaell appendage bu and inter-bud\nJomains [9897], suggesting a shared gene program fo\nsll rakers and other epithelial appendseea,", "Another main linding of this study is that parallel ceve’-\napmental changes underlie convergent evluton of gi\naber reduction. Despite the established adaptive sia\nince of evolved changes in gil eaker number and the\ncurrent phenomenon ofthis rll valving across many\nfash clades (reviewed in [69,120)), litle wae previously", "Evolved changes in peiterning of epithelinl appendages\npave occured repeatedly daring vertebrate evolution.\nFor example, in human populations, a dered alle of\nhe EDAR gene affecting hae sweat gland, and mas\nmary gland morphology underwent one of the suongest\nlective sweeps inthe genome [121]. Ectodysplasia sg\nnaling is perhaps used repeatedly during stickleback and\nhuman evwlulon because epithelial appendages are\nhotspot for evolation, as they form and function atthe\nterface between an organism and is environmen\nieorieoed ie Wa.", "the early Gillerence in umber and spacing of marine\nand reshwater E-post ake primordia suggests tha\nhere is an evolved earl-acting diference tn a ter\naibtary process Eaty Geawater decreases in Eder\npostive raker primordia number could be exphined\naraly by increases in Geshwater pimorda spacing, bu\neo to a eral extent by a decrease in freshwater el\nue, Future work vill atempt to discover which genes\nandere seMeback gil eaker reduction, and. whether\nhase genes affect tral inion In chickens, selection\nfar fess in hot climates resulted in the evolution\nreeds with featheres necks, cused by the upregulation\nfa inhbiory gene, Bop, during feather placde de\nvdopment (122) Since both acthating and. inhibitor\nsas thar camtpia, bh endl apis coctenl tae wpacinn", "Parallel Cevelopmental features unclerie stcileback om\ner aden" ]

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[ 1, 1, 1, 1, 1, 1, 1, 2 ]

[ "ee ee eS ee ees ae tee\ncvenleen tested compounds showed pronounced sti With\nsaves « 1 pM in bah cel ines Tue gy active itis\nbowed sigmoidal concentration elect carves with Tow baton\nteu nealing toa cell tal at higher test concentrate\nus} Overall 22801 appeared tobe slighty mote sensitive ha\nCPT, The manat active coangound wnt showea tn be a vets 1m", "anes ee ae ee eee ee ee\nales © 05 pM were also detected or 8b, 8,8). 8k and 80\nsh ea Cy values betes 05 ph ab 0 for 8, LB\nsed 84 The further bor (6 at ad Wp) exe mee", "Wine the structural requirements of ring E in podophylicvanin\nFT) have nat boon extensively lnvestionted become of the", "Cano Ue ae", "sthhemie 2. A possike Neocieafiil Of Dae loeiaieon Of The ehexpectod 4-a2apooopiy lotaail products | Bag) rormels & Cafes Chat Portia AL", "s 5\nOnes Ong\nQh, Che,\n7 °", "RQ a Te Olen, Oye,\nBip» Qs of," ]

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[ 1, 1, 1, 1, 1, 5, 5 ]

[ "ey ae ee eee 2\nSMD of 0.24 (95 4 CL-05 to 1.4). The subgroup ana\nys for SR-WBV'Slow-Go showed a SMD of 097 (05\nC1 “007 wo 200). The subgeoup analyss for SR-WBV-\nNo-Go showed a SMD of 080 (95% CL -032 wo 133)\nattialy non sigaleant in fvour of SR-WBN, with 3\nmoderate heterogeneity, F 425 % (p = 0.187).", "ror the comparison Wh) Versus conventional exercise\nive studies (7,50, SI, 60, 6) contebuted with & toa\nof 306 participants The pooled overall SMD was -0.20\n95 % Cl -067 to 027), statistally nonsgaicant i\nfavour ofthe conventional exercise group with substantia\nneterogenelty (F? 70.0 %, p = 0.010).", "Mgniticent in Gvonr ef comwentional exexciee. The enl-\nsoup aalyis for SS-WBV-Go-Go showed & SMD of\n“0.50 (95% Cl -201 to 02) with high heteropenaty, F\n86.3 % (p = 0.007).", "The pikgrenp snails Se SV-WEY-Go-Go mewed 6\nSMD of 20152 (95 % Cl -1.06 to 0.02), statistically nan-", "1 te subgroup analysis lor SV-W SY slow-Go showed a\nSMD of -0.07 (95 % Cl -0:38 to 0.24).", "— ey ee eS ee ee eee\nSMD of 04 95 % Cl -021 to 105), stastialy now\ncellent i ec Uk GE WEY,", "See SS Coe, ey ee ee\nversus non-exereise contal forthe outoomes lott\neength had a sigiicant Eggers test p= 002) fo\nsmal study bis. Funnel plots for individual comparison\nre not shown. Figure 13 shows 4 panel ofthe funnd\nsus tas octagon", "Pip Comparsion of WEN venus ENEICEE GFOURL Outnome: dynamic strength SMD standardized] mean diference, SD standard dewation, $5 6 €\nnavi easly frurtngsehnminad rg konami tring", "", "", "Functional strength: WEV vs. conventional exercise", "", "", "" ]

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[ "2008) INSn Worniers were assigned elmer to conditions requiring\npng interpretations of ambiguus words and event desertion\noctal onto a whch interpretations were sometine\nreatening aod socetines neta Inthe benign tring cond\nion, paripans fst reched homogrphe (ingle anbiguon\nord th bath eaten aod nan threatening mean su\nrots ee Coey 8 Mathews 2000) cies for sobving ward\nagents coreaponding tothe homogsipe benign meat (eg\nveh ~ pat) The second ask nlved listening to ambiguous\nsesrpns of worry related events that were resolved in bei\nmanner (cL Mathews & Mackintosh, 2000). Thus ba tasks\nued the adoption of the noe-heutening rnesnings of unig\nsous muleal and ejection af allernaties that were Mal\ncreasingly sina (ovals wor) content Thase allocated\nne conta condition were exposed tothe sare mate bu th\nsbi sequal often eave na theatening oi\nresent manger Te eects of taining were agin ascae\nng the assesment ofthe numberof gave intrusions thal\nct ding beaing-ocs pevods Delorean after iste\ned wory. Compared to the coil condition, fewer agai\nstron were reported by prints who had practice\nnchsivey benign resolution of sig, wheter costa wa\naoe a uae eee", "fe oe Se ee ee\npoduced equtalent findings (Hes se, Keebs, ta 2010\nThe benig-taied grup agatha ewer negative atrsns ha\nid the cro ro, ad ater test motion interpretatin\nupper Pasupt Fo, Mathews: 2007) cote tat the\nso made fewer negative interpretations, Mediation anal\nJemonsuated hat the elo wang on negative ntesions wa\nedad by interpretive bas Togethe these expeinentl fn\ngs provide song evdeace for out asumpton that emote\nresin bass cotbute casal¥tothe negative nus hal\nune", "A number Of rndings suggest that anxious inuwieuas are\nepaed in ap down attentional contol, even ia the absence\nspernentermposed Ihvestening evens. Ia 2 neuro sbi\nstudy (Bishop, 2009) patiants had to respond to target\neter while prong ther detacig letters under condita\nriven targets were citer ay or diel ond High eal nau\ndividuals were lowed mre by the presence of competing di\nracers (although group dilernces were spputeat oly he\nargts were relatively es) told ands ok up fewer ate\nsources). This slowing was abocted ith es actaton i\nto na reat vey sessing that ass nd.\nering tir an a ale ray wh\nstent with the posit that poor tentonl contol si\nctor fr pathologies! wor, abi wast sel ther Sp\nonto the combination wil make specs cl to en\nnase worry episodes,", "noe ciler ween Meniing about postive or worry topics. However,\nigh wares were Sess anda than lo” woes eve th\npve candon, perhaps de oat drench testo\ntrol oaleatseybecase gh wore continued 0 wot\nne etn! even sh the postive endo. Esther ay tes esl\nvie tong support for the hype ha wary epee\nata aur ees ue eee", "ee ae ee ee ee ee ae\nups eprting high or lw levels of worry were ake to wor,\nnk abut a postive top whe prlrming sar he) es\nsk Lpaes of tention vc in ton-rade sequence sh\nresin Keys rpeately in afd segue so ta the dee\napocty signe to he tak, Whe woning about their Ta\nony top uly high wores responded is ater ath\nhres ak (satin Ls tention coll alate oC\nee ee eee eae ea eeen ccna", "ee ee ee ee ee\n| nr spaal random lteval generation task ad not on\nirc tha wyatt fi ped tenon\nbout worry topics so ager far had eset — inthis ater\nondion high wares id ot dlr tern non worries Add\nnally the groupe did ot dier when pevoring the rand\nterval generation tik stone, Thea Rodings suger tha ay\nrae parent of attentional conte a pahalgial wor\nCL Bshop 2005) 3 exacted by the capture of atetonl\nsourer by wony Keele rene Heme that wory i\nreal fom is patty problematic ia ths respect, ul\nsinned nian", "Ivo iahirvinrber eel abehebaaraane tearm turn-in\npretation bas reduces negative inesive thugs (Hs eal\n\n009) More reevain the present conte, the same std as\neae that modifying negate interpretation bus eles th\nfepietion of atentanal cota veourtes by wor. A wel 3\ner supporting the ssc that wary dopiets stent\nenol theve reals aso show that the depletion eft ca be\nduced by modiying processing bis and 30 sees ail)\nack thonshte aieemioee", "et teas enact dead to incom oie\nhat attention to threat i promoted dec by anity oF by\npothetal “tveat evaluation “systems” (eg. Mathews\nckntosh, 1908: Mogg & Brady, 1998) Such models doo\ntray explanation fa bow bates aeacgied or aw they ca\npe odifedincogitive bie modification experients Hertel\nathews, 2011) In the preseat model af pathlopieal Wee)\nfearing eects over toe covert to btu” cot, by\nroi the unilenooslr-enctnet of the sate pe 0\npocesing that has Bee praciced previous, lacading the pr\nae shuekaieed cent", "expernents i which putin Pate fesponding to son\ncr ir exarpe, nares of vig things, tat witli\nsponses to ters (eg novi thing) I espns instruction\nre ter retersed, responses are slowed to the previous “no 0\"\nord ees in comparion to baseline revealing tha memories\nrevi praciedrespoes or of withholding response) wer\nVerbruggen & Logan 2008) Inthe same ay reminds of teats\nha have ben sepeately processed in parti ays inthe pst\nil end to evoke repetition ofthe same ype of prcering ve\nhat have been repeatedly inepreted previ inpatclt ways\npcome ae lly toe lterpreted in that Sane Way whe\ncout ater, ia boton-up sfveaces (eg Tea, Het\ncnncinaage tay", "EE a aS\nsa duudnediie “ahah teed cata uacececte @ eae bo", "impairment of attentional control by worry", "inviluntary “bottom-up” influences", "The role of verbal processing in worry" ]

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[ "Nee eT eee\ndco of dey aed re aformastionl change\noie et pein,", "The met eilicignt emagenes is tnpeiing Home Rpeegen pemalie\nwater abd oxen ae catalase [11617] Thee are tere\nse bls yeast, oe ta alsin the prasomes (i)\none th ese nthe esl dt maton mt (Ca)\nrill the ms detnieation eye othe SOD? pode ye\nson povoxide tn the autnchendhadd manta", "ane understanding of te rose of Wirathione in particular requires\nce investigation ass eleved that Qtthone play key 0\njr the operat othe mucin, ato kerpighe ROS es", "sembly machinery. The protein ofthis pathway interacts thal\ney geetate the Fe’ ster fom he cts ported on an\npen expert ore he cheers ito maticapoprtcs [A\norn ths acinery there ao the export soars, contig\nthe nitachonda ABC waasparer Ath ane memisane\nbeFAD bang protein and tine 73 Reel. thera\nrc of the pore Am wat salve in cope wih iatinone\nwitha proposed ech of sltathione paul expr\nronal ctr ssemby i the eto [W181 19), Se cen\nutes oc Mit presented i io ud vie rests emeonstaing\nat Wiad ean a bad toro cher ines ough he\nlye CPC mol, we i marl cei s deletion lea\nese to eves tear (2) 20-12] vas pose\nhee epors tae aceupain fhe active ty Fe chistes\nevened te neacton wth Ev, However, the rl the pep\nna it ht has a es cls Yound hasnt ben cae Ye\nathe protein that was shown to have a dul acl Both\nesa a ttechoo theo salu cast protein De\n123-125 hs ben shown tht De tras th Mit ndpe\nool the presence of eS cstrs on Dre? and ths interaction\n124) Laer studies alowed the lectin of Dred ut more deta\nlend ta tsa hy withthe ater emtrae a\nnd andi protest es ln [125 Te ae Dre\nbt one yates would be that each ssc\nre fggered by sei condone under ch he prota al\nevery othe on sles the it nt he etl\ntof the SC export machinery woud be ineresting Yes\nodes Meneihons ta ietcae eaeadenie", "Ee ee eee ene re Gree eee ee eee\nhe mitch preein inporpanay wa the europe\nDeans nd Dystnia Syndrome (127) This disorder cased by\ningle mutation of 8 to typoptan inthe human homoge\nin subst ofthe nidavedutse Mid [128 Tie parca\nruin of Tn resin the rt ering a eed sae\n\nHe unset proper estat ng nd nce eo acre\nvis pte Ten Tscasesaaliity oftaoonial dees\nsad lands tn pashaloggcal nae cheracommad iy daainane and Gpsmania:", "i ee ae\ngenta [19] The eared single pt maton fe\nvoten Sub and FAD nnding bu dos not the ety fae\nna tej. ter major buna dere tht ake oth\nsci pa SA Any ash she\nne die boa propey and core aged lia opal\nef he chon cto The pt SOD she MS es\nthe presence of Cs} whist Vatabyna et |] sowed hat Ma\nel te MDS compen regulate the por othe SOD! rats ha\nrelink o AS Fal, bra eal demoted hat gation\nsel forthe aetna of RSOD depen a the lea Cs\nch eeun tenia", "Saneeneeingy. Seisaeat sheenniiens Mek the qnitetians Siding path\nway partic everal human dese sts The human homolog\nEv called AL hs ee stented a ky aor dling\nseen te pra etc hee ae: Att\niver Regeneration) Reel an AL ruta (ISH) was dented\ntee cause tor the pathological candition of tatee siping eudleing foes", "ee\nerent expression ater in tumor cls a tale the eels\neal peste Koehdown of CHCHDA vas ae\nvith edd tuerprogressan al asked oe ty\nia teal omponet ofthe HE pay that sponds typo\nshina thet repr an asocation beeen he cb\nse ey syste at ear 136157) ote ak ote eld\neon py vo cance asus bythe fing tt 953\napart tuo onl ator hats eset the ed sale\nthe au arested ta mitochon in 8 CHENDS- depen\nrane 18 Oecegresio fe ndoredctae ested ines\nresol 55 ach whip ene stem\nronntnaiindinimeg", "suid sytem and the nerodegeneratve Huntington's disor\n1394) Ths ses character sya sh a uncon\nated maverent of muses, depression and sess, most ase\nsey mations inthe Hunting gee The eels NS red\npotest are ubutate fo the lie ly stem wet ee\nna mouse del of Hutigton's disease The maja the so\nhonda phenotypes eed, depended a the matted Ht\nrota eves Ane beeen ine fein kg Mad\nufodegeneation as Feprted bythe group a M- Con Ts\nnanan branched apintanseaseptein RICAN, wh 2\nredox chaperone conoling poten ising and aggregation\naoe naan yee nae", "Freee. sheer\\qaene chen pereenday a mareny Jaden\ncluster opens remains to be shown ts cata deel\nrtoondeal Fe’ duster byes res nen acamatn in\ntocando tsi ad eahanced ROS predentin\nfe pen rath, whichis aero te mt Sc nahi\nve en tong inked wit des ans (142-145 xcs\nron aca inmotion tox Thee\nech ete inercon a Fran wth the et the pr\n\nie emus howeve tobe eteaned Anther earpiece\nelated oat vel fon in itacondi the ce a eyth\n\ntc potoporpya whch hs ben ned oman othe ne\nce cr tr pe eng\nset wat detonated oe dic elect esha expres\naera ome", "ns ere eee eee\nonda rota biogenesis ith an emphasis he nave ald\nstein he nemebeae pce conection a ed guia\nhw thay be ed sverl aan dards espe\ners understanding the eel ad chan detals fen eu\non the fundamental processes of aitochondial protests an\nron sf citer binges canbe a uing pit in elcating ey\ninananinunes of s aan grou of nitachondrls elanad human fleet", "6. Links to the Fe/S chester biogenesis pathway", "", "" ]

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[ "Background: No recent Australian studies or Kterature, provide evidence of the extent of coverage of muficultural\npea sues in Ausvaan healthcare seach A senes of systematic ieature reves in thee mae Austaan\npekthcare joumals were undertaken to dscove the evel content, coverage abd overal quay of research on\nmulicutual health Austalan hesthcare jours Selected for the surly were The Medial Joumal of Ausval\nWIA), The Austalan Heat Revew (AHR), and The Ausvalan and New Zealand Joumal ef Pubic Heath (ANZPH).\nReviews were undertaken of the as weive (12) years (1895-August 2008) f journal ails using Six standard\nSearch terms: ‘non-English-speaking,, ‘ethnic’, ‘migtant,, immigrant, 'tefugee’ and ‘mufticuttura’", "Results: In total theve were 4,146 articles published in these Joumls over the 12-yeer period. A total of 90 or 2.206\nofthe toa ales were areles pearly based on muiialtal sues A futher 62 aes contained a majo o\ncschwose beral of conaislrvtion «f ruhiccisd lena erdl 107 heel adios mentions", "Cmceipes Tne CRETE BC! FENCE OF ITRAREACUT Na PERCH Bic! eNcAerce eacpaned for eqpty In pokey,\nsence, nfrvetions and plementation fed and uneven. Most ofthe enignal mulcutural heath research\naides focused on newly arved refugees, alum seckrs, Vietnamese or South Eas Asian communes. le\nher s some seminal research n respect ofthese represented groups, there ae other communities and heath\nssues that ae essentially invisle or umepresented in research. The ited coverage and representsion of\nmulticultural populations in research studies has implications for evidence-based health and human services policy.", "URN Se Meche, BOGE Settee SG ant a DER RNCALE\nvironment incteasiagly commitied to evidence-based\nvolicy, may ultimately produce poor policy.", "Moainetrenm healthcare research can be pencetved 44\npeing neglectful of cross-cultural research Iti fe\njuently sen as methodologlaly dificult o do with sg\nlant interpretative problems (1,2. Resources my be\nadequate forthe translation of study instrument o\nhe employment of bicultural researchers and inter\npeters. Concepts do ot always have semantic ofl\njulstic equivalence across linguages oF cultures [3\nSampling methods, subject recruitment achieving ade\nquate sample ss and representative samples may pos\nditional challenges [5]. However, i can equaly be\nrqued tha to ignore populations with limited English\npotency may result in pooe study validity and gener\nslisabilty, could be considered. discriminatery in", "Repassentetions of imunigrsnts Reve sliRed consider:\nbly in the period since the ead af World War Two.\nThre years ago eostcultural health searchers woul\npave studied ‘migrant pails lle ate, paint\nrom non-English speaking buhgroundsat that tine, 3\nJfinable (constructed) field of std, which assumed\nhat the simarites witla these group allowed ther to\npe neatly categorised, labelled and understood as one\nentity. From the post-World War Two period tothe\n160s, the presence of smsmigrans was basally ignored\nThey were expected to be invisible and assimilate int\nhe dominant socety as quickly and a6 fll as posible\n7], Reseach studies india that, i the 1960s, doctors\nand psjehatists developed an intrest in exotle migrant\ndisesses’ or pathologies and the ‘culture-specific’ health", "Pamela W Garrett’ , Hugh G Dickson*”, Anna Klinken Whelan”, Linda Whyte’", "Representations and coverage of non-English-\nspeaking immigrants and multicultural issues in\nthree major Australian health care publications", "Abstract", "Background" ]

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[ "milk ond rawemilk cheese was defined wsing both the\nfrequency andthe period of consumption ofthese types\nof diets of bovine origi, reaching a numerical estimate\n“ifetime consumption” (days). These estimates were\npase on the reported nue f days none episode atid\nhe Fequencies ofthese episodes combined. We ess\n\ned ations as having ZE ithore was () dtet contact\nvith bovine vesock via arogonic ruts (occupations\nlated to both bovine livestock apd the apr0-f00d in\n\nlusty of bovine origin, (i) consumption above medisn\nevel af bovine favmik and (i consumption above\nmedian levels of raw-amilk cheeses.", "Siatierical analyoss feane-control sedi « Date ware\nanalysed ss a matched eate-contol study. Cotliionsl\njoist regression (CLR) was used to investigate the\ntionship between an outcome of beng ese or con\nrol and a set of prognostic factors.", "The case-contsol anstyses wore carried out in a two-\nage proces. Fis, univariate CLR analyses of ll var.\n\nbls of intrest were evaluated. Second, variables that\npesentedpevae = O10 inthe inal Screening were\nvaluate using mulivayiate CLR. These variables were\neluded inthe mutvarite CLR following the forward\ntepse (likelihood ratio) method. CLR. model were\nverormed using SPSS software, version 20.0 (IBM 2011),", "In univariate logistic regression analyses, if some\npet of exposure had all eases exposed, tha would\nJeerae an indeterminacy inthe release of odds 13\n\nio (OR) results. To achieve the same goal, we applied\ngonad approach to matched data as stated meth\n\nnds for spe data (Greenland 2008). In this appeaach,\nsch sot of matched cases and contos were conidered\nstratum. Using this satay was posible to apply\nHaldane's corrosion ad cease approximate maxim\n\nikelihood estinstes of the common OR values tthe\nunivariate analyses, sing OpenEisftvare (Dean etal\n\n2013), Haldane’ corection involves sing 0. al of\nhe cells of a contingency table any ofthe cell expects\n\nons would case a division by ze eter. Acco,\nOR and 95% confidence intervals (Cis) were shown,", "In the case of multivarints CLR analyses, if some\nype of exposure had ll eases exposed, that would gen\nTae a frequency of zero in any single call of the table,\nvhich implies quasi-complete separation. When quas.\nmomplet separation happen, it prevents the conver\ngece ofthe maximum ielihood etinates forthe coc:\news In that case, we only fepeted liklihoed ratio\nh-squars for complete and partial model. In all CLR\nanalyses, p= 00S wat take to indicate significance\nThe software Ep fo version 3.53 (Dean eta 1998)\nvas used for data management.", "Zibics - The eidy was approved by the Resessch\nEthics Comite ofthe Federal University of Iz de\nFora (protocol 810.125.2006) and Jo Ponigo Regional\nHospital (protocol 5208) Participants wore informed\nout the cbjectives ofthe study, and written informed\nscuee une oiaten", "counselling prior to being asked Ser permission te carry\nbat HIV testing and post-test counseling, acowding to\nvuidelines on ethies for health research", "Patients with » positive diagnosis of TB and HIV\nceived therapy avalable from the government med\nat bovine Au callous au oreo atk pete", "Description of the study population ~ The prevalence\n1.6 OFM. ovis among a Sample of 19 individuals di\n\nposed with TB in Juiz de Fora, an whan ate of Beal,\nhd descriptive characterise of that population have\neoviowsly been eprted Sia eta 2015) That sample\nvaste bass for the cute nested matched ase-contol\nuy. Bey 186 984%) ou of 189 patents presented\nvith only M. ubereudsis, and thee (16%) also ple\n\nete wth MF. bovis in addon to tabercudst. Ta\nhe sample, 18S patients (974%) lived in an urban area of\nJuiz de Fora. Altogcther, 1S ptins (7.9%), 72 G8.)\nand 46 243%) were current, former and ot consumers\nahovine raw mil, especie and 86 29.7%) id not\npave such information recorded. Repatding derivative\niy products, 9 (3.290), 1 (27%) and 23 (12199) were\nurea, oemer abd ot consumers of bovine ai\nhoeses, and 86 (29-4) didnot have sub information\ncorded As foe Bovine contact, 6S patents (344%) had\nhistory of occupations related to bovine livestock ar\ngroan indusees of bovine origin while 67 38.5%)\ndidnot: 57 (30.4) id na have such ifsmation recor\n\nod, Regarding HIV status, 6 (45.5) paints Were HIV-\nmegatve and 24 (127) were HIV-positive, 79 418%)\ndno consent to ny secoopical diagnos or HIV. The\nnim, median and maximum lifetime consumption\nals were 0,18 and 20882 day fer bovine raw milk\nhd er, 279 and 21840 days fr bovine aw-milkehoese,\nspectively Table | shows the proportions of exposures\neach possible variable by co-ineeted Movi.\n\nperculsis paint (03) an Muereaass pains (a\nna pelaerod ec as castchand cues eee ha", "Risk factors for M. ends infections - The waiveriain\nCLR analyses identified that individuals who had EPT\n()= 0.039) ad lifetime consumption above median lv\nsof ovine raw milk cheses (p= 0048) and reported\nZE (p ~ 0024) wot significantly more likely o be Mt\nbovis positive cases (Table 1).", "Affler adjustment for potential confbunding thetors,\nwo variables remained independeuly (p= 0.008) asso\n\nated with zoonotic TB: EPTE and potential zooneic\nsxposues, This final mulivariste model containing\nwo vatahes (ETB and potential 200aaic exposes)\nowed significant changes (p = 0.012) compared to the\novis step (nly the EPTE variable included). Table\nhows that ely likelihood ratio chi-square fo he co\n\nplete and partial models were preseited instead of ma\n\nmua iklinod estimates forte eoetiients, because a\njuasi-complete separation condition was detected.", "Tals is tho first study to evaluate risk factors She n0-\nnatie TB in Beal. Despite the small number of eases,\nisk factors associated with 2aonatie T could be iden\n\nied and ineluded EPTS and ZE by occupation andthe\nconsumption of raw milk and derwative' products that", "", "" ]

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[ "———E——\nroupe were erigally eovsoned to increate the dance\nRtwcen payor chains of PIM-EATE fa ene high perme:\n\nny Instead, tpjeene war considered at 3 desirable alten\nstv bile bung unit a ha een ed extensively to\npci Ree vine td inci wicvoporacty wim ply\n\nmers) The uae of tipigene og IN Top-TE (Figure I)\n\nvat antipated to maintain interchain distances, itu the\nneed for bridgehead methyl eubstituents,", "PIM Hig Te peened sebust wih 6 Tags sedetes of 108 £\n(2 MPa and tena srenpth of 4.6 #32 MPa, which are an\nimprovement onthe equitalent ales for PINCEATE, \"= apd\nmi ranemy viahe-hapeinnrriaea", "PIM: Trip-TB is prepared in tree simple steps irom commer:\naly avaible eiptyeene, The final step ivohes plymeriation\nof 267) damincrpyene™ by reaction wth sx equtalents\nof diethoneathane in iluorooetic x (FFA) a ambient\nenpestre The rvuling paler sx soluble in chorlorm\nlowing fr analjis by Cel. Permeston Chromatogapy\n(GPC) which indicates hat »reaeonably high average oe\nla mast was achieved (My = 21 00M, = 50 00; elie\nlave polystyrene standards) An apparent BET (Brana,\nEmmet, Tl surface area of 899m \"coud be aed\nrm the Ny nother fora pondered sample of PIM Tp TB a\n7) whichis estat it obianed forthe rested per\nPIMEAT (1028 mg bt higher than the ange quted for\nPIMA (20-820 mg) inthe Ierstare Te bation\nopty cear Bene sabe for gx perma states\nwas achieved by casting from chlortforee solution. Films of", "The pt pocuaetiiitivs of o Mins of PIM-MipTR of 152 pan\nhicks ae ge in Table 1 togeee woth the caesponding\nae fra er Bin of IM EAT (182m) whic re im\n[rt the resent repaid! Priorat ln were\nerated by rerio tials thie known ees he\na pp ageing oe ey pra pep end\nen remove the bet eis of he caving save ™ Hence\nhs treatment alls dct comparison betwen the at poe.\nabilities of the different polyrners ia an unaged state.", "The onder obs permeabilities for the tea mesane\nccted lm of PIM Tap TB i CO;>H,90,>He-CHON, which\nfeet fom that af PIM EATS (H,2C0 >He20,9CH>9)\nisa fo moe er PIMs. Gate value of ox pero\n\nsites are bain for PIA Tp TH oer PIMLEAT wth he\nscepon of He al, which sre ima This enhancement\npray notable he film of PINGTep TH was thinner\nhan that of PIM-EATE and, generally for patsy polyenes,\nhe gat permeablies fr thinner Slims ae lower due othe\nge oie cot of re ore dene poche suraee\neons ofthe im.\" OF paiular iret the greater\nCO, pene fr PIMTpTB. nado, eal ade\n\ntes for PIM ip ae sigan higher than thse of\nPIMEAT for some important ga pts (Ox/N COs/CHy\nnd CO, what sar for thers (4,8 yf ad Ha\nCi, Hence the permeability data for PIM THD are well\nove the Robeson upper bounds for ON, (gure 2), al\nN; (igure 2b, HJCH, and HCO, In pati, the strong\nchanemen! in O,/N, perrmance vndeats the choke of\nperme a tocar eto ce fii edectidy\nthe separation ofthis yas pir relies slmort exci 08\nae slecinty bated on only + sal diference in knee di\n\nmeter beeen the gas leu Inport, the PIM Tee\nTB data fr CO/Cy Figure 2) nd CO,/N, (igure 22, both\nie vey clon to the especie 2008 upper bonds in ontast 6\nhat of PIMLEA-TR, which fall well belen,", "Baysica’ ageing (i.e. loss of re vo ume over time) is a gen:\ncal etre of ity paimeni™ andi aberved for bath PME\n\nTapTB snd PIMEATB (abe 1. The vate of ageing i more\nsid in thier fs and therfore, 16 allow det compa\nsan the vale quoted are fr 360% redaction ofthe oil\nalc of PO, which occurs afer 100 das felling methnal\nenna forthe thinner fim of PIMC Tip TH (132 hm) ad\n(70 days or that of PIMG-EAT (80 un. IM TTB apes\nyccflly with a coresponding enhancement of nec\nfo the eduction in permeabty 0 tht nes asin the\n\nse st aged data pans onal the Robeson plo te pre\n\nmately prallt he upper bound fr all imporsnt pa ps\npure 2} Forte ON ga pai the cect in vr of O,\n25,7 fora vale of PO, gree than 1000 Barer exception\n\nin adtion, the data for thea film of PINCEATB cose the\n208 upper bound fr COC Figure 2) and x cmparale\nvith the data of the bet peering Pits fr thie commes\nwally bepenet gee acres", "ee ee ee\nof a gas theough a dense polymer ix dependent on both ite", "SEO en Structures of a} PIM-I; B] PIMEATB and\nSPM .NipTe.", "=\nou\nL> CN\nf GU ox “y\nPIM-1 eal\np) e\nHI\nc) ()\nil" ]

[ [ 51.02, 449.57, 294.21999999999997, 547.7 ], [ 306.14, 75.05, 549.3399999999999, 119 ], [ 51.02, 548.57, 294.21999999999997, 723.7 ], [ 306.14, 119.31, 549.3399999999999, 218 ], [ 306.14, 218.86, 549.3399999999999, 503.99 ], [ 306.14, 504.86, 549.3399999999999, 701.99 ], [ 306.14, 702.86, 549.3399999999999, 723.99 ], [ 51.01, 412.24, 293.96, 430.76 ], [ 75.44, 75.7, 267.51, 404.45 ] ]

[ 22857.09560855804, 9665.945403571008, 42432.865928296, 23318.535197009565, 68176.25597129576, 46200.5369940158, 5029.623352260329, 2689.387472874718, 63144.05414400003 ]

[ 1, 1, 1, 1, 1, 1, 1, 1, 5 ]

[ "pip tel eh lial phar lira anal\nmacolgical and non-phammacological modalies* Thee are\nvera repac of minorelicao eucatonal program on pa,\n\nuncon, ime pantn gyms and weight ae *A evs postie\npenance ina weekly educatna program on pets who\n\neapotos nse the preset proposal ot wo das of lectures\n2d worshops abou Oh patent with knee OA (KOA) at we\neiforesd by elaphane cals Our one-year eat fale sow\nleva olifrence inthe groups that ecevedilephane cals\nBecause hose llores cals were ira-consumng, they were\nsuspended nthe second yea! This sid evaluate he Moyea\nls of @ mul- professional onserate veatnent lr patrts\nshKOA by compaing the alernget he aducabonal program wih\nwithout asses by assessing the subjective pan uncon ar\naly of questonnares and by objective measures (BM,\n\norceriageo bodyfat PBF) unclon tests anc engagerant in\nequler physical actity.", "ee eee SG PSP eee eee eee Be\nrumstlogy, S80 Paulo, Se lr racsvng arora am fhe\nhis Commits othe Analyt Research Projects (CAPs)\naie cio erbereaintl", "Clincal tials registration number: NCTO1S72051.", "valet anor hcaae oposite aaraarans A\nplowedthe gucsines atte CONSORT sazenenisorandemzed\neenrandiy! rapcarnebrfueeinrclichg", "ine cone proukiens Incaied elt orthcpeects sugeces, fur pay\nnolo ve socal otere, one uiionst, ve occupational\neras, hes pyscl heaps ana wo ysis educators,\nlof whom wera voters oat the Otnopsede ee,\nsatiation hoon, Lnleeedip of Sie Pauls,", "Patients had to meet the following criteria: outpatient aged 45\near or older wih KOA accoraing tothe American Calege o\nRreumsobgy cial andradelogeca defion® no rheumatoid\nhits of any eumatioge dbase ther han OAhadrocaived\nvpcacate fo OA hepa suments knes pal aed above 30\nrenon numerical scale and naeastsing crag eaten hou\nny naurlogeal problems. and able oundertaeand prove\nnfomed consent The exclusion crea included undergoing\nSurgery dung the study that was no lated to OA arc woud\navert daly e9.aoxroseeparicpatnginanctarrogam wih\nnational educaton or engaging in another inca a. Patients\nsho wete net abso perm he unctonal ests al base wee\nsecluciod only from the functional analyeie.", "Pemmcipants were patients uncergong typical care foy the veaimant\nKOR atthe Osteomstatoke Dassaes Group. Department of\nOrthopedics and Traumatology Hospial das cas, Unies\nSoe Pal. 8 January 2012, patents vere undoing pa\nce ee oo caret!", "Mt erClnert, petenss were selec! 1 esspond i fie WAS (View\nmnoguoSaig WOMAC™, Loquoae, aS 95qussirnares and\npastes efequency and irat ol pyscal acy porlomed!\nveo Wig, hah, an sven skinfold wee Messed 1\nalte boy mass nda aM) arcpecortage a bod) tPF)\n\nans wer ala peor tnd up-and-g TUG an res\nit sland FTSST tests Al pants ecaved apn adogagh\nhe knee, incung weight baring arte poser, ea\nns pata il vw. Three othopsad surgeons examined al\nacta to cass ne sei OA accorang to Kaleyen and\nrence (KL Incase of sagem between two sugeons,\n\nfr tric eurpann was decioha.", "Participants were randomly allocated into exght subgroups (1 1o\n{scoring to he sna betoeen das faces nA and\n8 according tothe oe or absence of elaphene cl of 28 29\nparispars each The Class group ha ak subgroups named\n2, and whch ha ectures one two and es month ca,\n\ncept, ether wih) or thou) mart lephons cal\n\nSubgroup 4 (wh (A) and wheat (8) meet tlaprene cals)\ncoated nacducatorl mata ony ardiomadte Ca geup,\n\nPars in each Clos subgroup were asedicometo he hepa\nan two spectcSaurdys according othe eral ofeach cup\ns aveccoana lee ecuelraliomeeeen?", "nl participants received the waltien ancl video (V0) iniormeion of\nne lcttes given onthe fist day of class The DVD was 2 hous\n29 anus long Pallets om aubgroupe 48 an aE ached\nre OWD fr helt ie athe Peep Allpatents woe asked\nead the taxt andlor vctch the DVD at hame at least wea tinoe.", "rhe physicians called patients in subgroup A two months after the\ncre and evry oer month ul the year reassessment\nintone fhe inkliotion phon in the adrenal propane", "Reales cl 24 momdhe after the fine lechap ox cer escehing fp\nsdscalonal ara he pater eturd tr evauaon, whet\ncarne seneaamenta portormed at baseline were eepoctad.", "This ae PCR lucy 1 maul the electveness of mt ny\nrogram abeu OA with espe: the sole cet educational\nrar oot and DVD) wih pacar nas between clases\ni elpone eal, The authors aia for 20 pant n each\nsubgIOUp.", "Re eT EON Wee Performed’ by @ computer- generated program\nsvadabla ot tse ureecrenumnizedoncoen.", "rene ee i See eg eee eee\na goups. Groupe Ifo 3tecewed classroom instruction fom\n= ptersonals an bath audiovisual and wrt tons,\n\neh go tala received, When sgnng te armed consent\nrms, the patints Knew hat the groups woud fer according\noe ne betsen class lok eaeees and eephone al\n\nvali’ di ot koow'o which goup he pir bebe Tao\nmain asssans scheduled spponimens an cases, ereved\ncoiiol. wel ciciaxd fen auecicereiae’ unadie In Encalsheaee", "pad slpharsh-enpernadedmrnipearpeninwhansh:Hesiharh bend\nbsolseardraatve quence and he existance a arsocatons\netwoon group a tues a ered uong the aqua eat\nsanelleihendra fo tace, OA sever was compared bawoen\nfeups using th Kruskal Walls test. Quarate characters\noe deserbederhe groups sig sunmary maa and wee\nsompatedbetweengaups using Anais Vaan (ANOVA) for\npeated monaurea ilowedl by Tukey's mutiple comparionn tet.", "ghee ta aah thd hella\nrants of evasion sing summary meaaures (ean. tnd\nJovalon and 95% confidence cra Values Were compared\npalween groups, lephone cals and members (l assess)\nsng ate ace ana of variance wih repeated measures,\njolted by Tukey mutpe comparison at to compare ICups\nslophone ralle endl moranta of oascoamart when monde", "featalions {>henges) In the tunciion, peln and quay of Hie poores\nverecalated, Crangos nthe Gk ant percentage betwoen\nre two-yeaelow-p andbaseine were ao measured Subs\n\nerly, Pearsons colations were cetemired between hose\nsar-slyapenphccnnan-varepadhauplnedia-ar-ediienand", "METHODS", "Sample", "Blinding", "Statistical analysis" ]

[ [ 42.52, 69.62, 294.03, 255.28 ], [ 42.52, 280.93, 293.96999999999997, 324.51 ], [ 42.52, 324.64, 229.16, 335.43 ], [ 42.52, 335.58, 294.03, 368.22999999999996 ], [ 42.52, 368.36, 294, 422.86 ], [ 42.52, 423.02, 294.06, 564.96 ], [ 42.52, 565.1, 293.99, 619.61 ], [ 42.52, 619.75, 294.01, 750.76 ], [ 303.64, 69.34, 555.16, 187.45 ], [ 303.64, 187.39, 555.14, 241.10999999999999 ], [ 303.64, 241.04, 555.16, 273.3 ], [ 303.64, 273.24, 555.13, 305.5 ], [ 303.64, 325.08, 555.13, 378.79999999999995 ], [ 303.64, 378.74, 555.0899999999999, 400.26 ], [ 303.64, 419.84, 555.14, 516.49 ], [ 303.64, 536.07, 555.1, 621.99 ], [ 303.64, 621.92, 555.16, 697.0999999999999 ], [ 303.64, 697.04, 555.14, 750.77 ], [ 42.52, 265.75, 87.93, 276.54 ], [ 303.64, 311.51, 335.07, 322.3 ], [ 303.64, 406.28, 338.40999999999997, 417.07 ], [ 303.64, 522.5, 381.63, 533.29 ] ]

[ 44889.57761713443, 9587.407358615834, 2014.0800441299943, 7206.5017780617345, 12919.090806966997, 34729.579703711905, 12149.763501621084, 31455.00302566169, 28695.637477144017, 13442.100818898878, 7852.019224654185, 7789.7589178205235, 11234.289828129113, 4512.821180054219, 24252.624896666035, 21576.549038915895, 18645.928202971816, 13486.483904855791, 489.96535500000755, 339.20947368003544, 375.1862360399682, 841.5516740400344 ]

[ 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 2, 2, 2, 2 ]

[ "a a ee\npoximately half of als among adults aged 65+ occu\nmn utdoor envitonments [10-13]. Outdoor als als\npave isk factors that are distinct fom indoor falls and\nre linked with risk exposure [14] those who fall ot\nJoors are more likely to be male, younger, and moe\nphysically active and heathy (are more independent\nim aciviles of daly ving and have a faster gat speed)\n10-1315-20) However, despite the high frequency of\nnutdoor falls and the distinct emergent set of rik fc\nor deserted curent dfitons of ls do not tingish\npte indowr and outdoor fl [2], Ths, curret guide\nins fll prevention recommend modification ofthe\npome environment asa component of a mulfactria\nnterventon, but include no specie recommendations\nor the prevention of outdoor falls [7] and no guidance\n2 local authorities and other bodies responsible fo\nmaintaining public areas. Consequently, beyond socio\nJemogeaphic rk factors for outdoor alls, Known\nnthe context in which outdou ills occu, how Fates\nnf the external environment can present as sk actors\njor outdooe falls, and which outdooe fall te move lel\n0 lead to injury andjor fear of falling, The eureent\njualtative study aimed to begin to fl the above two\ngps in the falls Iteratue by examining in det olde\npeoples reuospectve accounts of outdoor fall The\nins of this research study were therefore t9 explore\nhe contextual factors associated with outdoor fall,\nand explore the intereationship of these factors with\nary ead Soar oF ion:", "we ee re ee eee ee\nsoups of around three to seven people that are fell\nated to comment on a particule topic [22.25], Although\nnr wo interviews, the group contest of focus groups\nmake them ideal for providing a breadth of experiences\nand views on a tope [23], and for gaming access to par\nscipans’collecine understandings [24]. While data ob\nated fom focus groups may nok generalise to anion\npopulation, such an exploratory study is important in\nder to highlight arse to be emphasised in future\narge-scalequanltative work. Focus groups were an ap\npropriate tol to collect exploratory, qualtatve data on\nhs subject given the pauity of esearch ia hls ate\nand our aim to acertan several older people's views on\nhe eesearch question. They were also Weal asi afforded\nse of recruitment across the United Kingdom, a de\nalld below. The focus group schedule was orientated\nround our main research aims and tc sub-reeearch\njuestons (ee Additional He 1 for the focus group sche\nle). This paper dtals the ndings in vlan to ode\nseople’s experiences of outdoor falls", "A purposive sampling strategy was employed in order to\nently older people Iely to offer a diversity of views\ndating to the research topic. Given that this study\nconcemed older people's experiences offal in outdoor\nvironments, we were interested in recruiling pate\npans from different geographical contexts, For this\npurpose, focus groups were conducted is both urban\nind rural are in five diferent locations across the\nUnited Kingdom (UK), representing north Seana), west\nWales), south, east, and central parts of the UK (thee\nites in England) (sce Table 1- ln addition to purposive\nampling at group level, we employed quota sampling\nan alfempt to eeeruit participants of both gender,\nand telatively younger (aged 65-70 years) and olde\naged 280 year). Ths strategy was largely successful\nthough we experienced difluly in reculting men\nto the focus groups The Indusion criteria for pate\npation in the study were: aged 65 and above, able and\nwiling to reflect on thei own and others experience\nnf outdoor falls, experienced an outdoor fl nthe past\n12 months, and curently going outdoors as a pedes-\nius at least euice every wae", "een ne eee wwe Conducted nine\nocus groups with 3-7 (median =5)parlpans per group,\nsnd a total of partpants. Partispants were rected\nheough voluntary and private organisations, and lod\njuthortes. Participants were dented for fous groups\nther through the ute of existing contacts or through\naking conttet with venues tat alder people frequen\nuch as day centres and social club, Participants wer\nnot screened for long-term heath issues, however,\noup of older people with low vision was recruted\nfromm a voluntary organisation as they represent those a\nam Increased isk of cutdoor falls (14,25). In addition,\nwe recruited users ofa post ll service provided by the\nNational Health Service (NHS) as they tend to represen\nler clder people who have experenced an injurious\nall reguling medical eatment. NHS patients wer\nentied bythe direct care team either a ital ame\nats or a the beginning of exercise elatsex. For each\naeus group, those who expresied an interest in the\nstudy were seat letter with an information sheet by\nhe focus group faclitator, and Hf they met the entry\ntera and agreed to participate, were eeerited into\njacus group that was arranged locally at a mutually", "Reteee recruicnent comenenced, Appecwel wns precited\npy the Research his Committee of Bournemouth\nUaiversty. In addition, forthe focus group conducted\nwith NHS patients in Scotland, prior approval wa\n“rovided by the local NHS research ethics committee", "Methods", "Design", "Participants", "Ethics" ]

[ [ 56.69, 88.54, 290.64, 447.43 ], [ 56.69, 484.54, 290.62, 735.4300000000001 ], [ 304.72, 100.5, 538.64, 363.41 ], [ 304.72, 364.51, 538.6500000000001, 651.4 ], [ 304.72, 676.5, 538.61, 735.43 ], [ 56.69, 459.4, 96.88, 471.19 ], [ 56.69, 472.54, 84.17, 482.98 ], [ 304.72, 88.55, 351.73, 98.99 ], [ 304.72, 664.55, 327.98, 674.99 ] ]

[ 82363.63937355811, 57614.282786003314, 60185.14068959467, 65015.82454397902, 13782.240965507925, 473.98784110001, 286.95657488470897, 490.8619415377907, 242.86113870388363 ]

[ 1, 1, 1, 1, 1, 2, 2, 2, 2 ]

[ "Rergrerees Accomiing to French netong RcOmmendaions, te Catection Of 8 pelient colonia wilt\nslyeopeptidersstantenterococc (GRE) lads to interuption of new admissions and transfer of contact patient\n(CPs) to another unit or healthcare faclity, with weeldy screening of CPs.", "pean We Syeeeew ve Cicer a BOO Ibe ore Pee eee\nssoiaed witha realtime PCR RTP) (Cephea Xper™ vant van) ae part ofthe strategy for controling GRE spread\ntwo medical wards Screening was previously performed using chromogenic selective medium (CSM). Tan\nround time (TA, cos of tests and cost of mised patent days were prospectively colcted. In February 202, the\nentiation of GRE in one patent inthe dabetclogy ward led tote screening of 31 CPs using CSM one second.\nry case was identified in 8 CP aleady transfered to the Nephrology war. Awating the resus of SCM (median\nTA, 705 F, 4 potential patient days were mised. due to ntenuption of admissions. The overall cost (crering\nets + misng patients) as estimated at 14, 30220 € The secondary cae led to screening of 22 CPs inthe\nNephvology wad using RTP. Because of a shor median TAT of 46 h, we did rot interrupt admssons and patents\nvances Avong 22 CPs, 19 (6) were negative for van, 2 were postive for van and 3 had invalid rests need\nng CSM. The overall cost ofthe suategy was estimated at 47040 € (os of Screening tess only), without missing\nshir tng", "Seger SO ne eet, Oe ee ee eure (Oban Gece Oe ie er\nrdection control seutegy and prevented lows of Income dus to diacortinusdon of potient wenalers and ecrissiors", "Keywords: Screening, Glycopeptide, Resistant, Enterococci, Cost, Decision-making, Search and isolate", "GRE (mostiy wewA. gonetypes) smong E faecium blood\nream infections in France declined fora a 3.2% peak in\n2006 to platens at about 1% afterwards [5]. However,\nhie strategy is burdensome ad lite the use of hoxpl\nvies, resulting in both missed opportunites for pa\nMonts and decreased income for HCE.", "lycopeptie-resistant in enterococc! (GSE) Mave risen\npidly in recent yeas, posing a particular threat in\npealheare fees (HF) [I], Several countees have i\ned national guidlines for controling thelr spread\n23], French recommendations const af stele come\npecautions for calonizd patients in sreening and\nston of contact patens (Le sharing the nursing sal\nwith colonaed patents), with neither wansfers of pa\nents nor admissions to the lavohed ward unt thie\nnegative weekly scveening tests [4], The percentage of", "ES Oe eee Caen See Se ay\necopeton of GRE colonized patients by rapid and ac\ncrake screening tests. The Xpert™ sytem (Cepheid\nSunnyvale, CA) is a one-step PCR assay providing\nule generaly i ese chan 1h with a hgh negative\npedicle value (NPV) for GRE detection in etal spec\nmens, However, the camiage of vanB gene by other or\nganisns chan faecium gives a weak polive predictive\nvalue to the test [6]. The purpose of this study was to", "Gabriel Birgend-”', Raymond Rulmy’, Micheel Schweringer'”, lebelle Lotony,, Gistle Bendjelour\nNadia Houhou’, Laurence Armand-Lefeve', Antoine Andremont, Yazdan Yazdanpanah!?®\nand Jean-Christophe Lucet’2?", "Rapid detection of glycopeptide-resistant entero-\ncocci: impact on decision-making and costs", "Abstract", "Findings" ]

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[ 1, 1, 1, 1, 1, 1, 1, 1, 2, 2, 2 ]

[ "were characterised’ by iniration of monoouc ear inliam-\nator ells in HB stained sections (Fg. 3. Luna st\nue (Fg. 30) and Bielichoesky sver staining (Fg. 3h\neo showed mrked myelin le ad severe axonal nur,\nspectively, particulary around lesioned tssue within the\nJorsl column af the spinal coed. Analss of histoloia\nction from the mie transplanted with fve millon cells\nvealed Kite calle inftration with mini demyeli\nom and axonal damage (Fg e.g. Furthermore, we\nsessed IBA-I+ amunoreacthaty, which tains microglia\nand macrophages, within diferent regions of the CNS. A\ngnficant decrease in IBAL+ cls was found in bith the\nhte and gray mates ofthe spinal cord flowing MAEC\nsdminseation compared tothe PBS contols (Pg 3) k\nrespectively). No diference was observed inthe cortex,\npervencula, or subcortical white matter (Fa. 3). Cal\n\nctv, administration of BAECS into RICEAF ress i\nielorstion of beh cna and neuropatholoial sgn\nfon", "wih a increasing cel Gose (ig. 35). Bhe two lignest Coses\nOT RAECS sigicnly reduced the curultve dee sor\n(P00), tend that was almost significant following\nsdminisation of only 01 millon hAECS (P= 0056\nFg. 30). Administration of 05 millon hAECS signi\nnly reduced the maximum disease core compared\nothe DBS contol group (P< 05; Table 3. No sia\nrant differences were observed between the groups in\njerms ofthe disease incidence, day of disease onset, o\njeath due to severe disease (Table 2).", "2 en a eS ae\nRI-EAE, we tated the numberof elle administered to\nJtezmine whether suppression af EAE by hAECS was\nJose- dependant To that elec, hAECs were administered\npat tre diferent concentrations 5, 025, and lon.\nA dose dependant attenuation of EAE severity was observed", "Having chown Get BAEC ademinigizerion senellecetes\nRILEAE dicase seventy in 2 dose-dependant manner\nhe efect on peripheral lmmune responses was then ex\nined. Splenocytes from the Weated mice Were bated\nind simulated in vitro with ether MOG or a-CD3)\nCD28 for 721, In comparison tothe PBS contel group.\n| trend towards decreased MOGspecie proliferation\nwas seen fn the RAEC-teated groupe receving either\nbse oe five aillon RAECS (Fi a). This was accompa\ned bya signiant decrease in IL-17A (P05 Fig Ab\nund TNF secreted in splenocyte caltures fom the\nmice that recived hAECS (Fig 4) In conta sia\nnt inereee in the secretion of the an-inflamanatory\ntokine IL-4 was observed in the mice that recived\nRAECS (P< 005; ig 4). No derence in MOG specific\ncretion of IEN-y (Fig 4) 1-10 (Fig, ) was observed\nptween the groupe Itt noteworthy that dis cytokine\nrole of decreased I-A7A and Increased IL-4 observed\nfllawing AEC administration was also found tobe dose\nlependant (data nat shown).", "ane elect of BAEC adininistrabon of nan-specilic per-\npera immune sponses was also detemied by stim\nae ipleuncrin Oo Col CHINCHIOA Dae een te", "Fig. @ 1 cel responses in FEVEAE mice following HAEC ackmunetration Mononuclear cels were solated from the spleen of NOCYL mice at day,\nPela pase ot noes strated wh MOG er COB hb Care eacion pe vapertant far MOG\nried pape uc: one seawton le sup fm aecDCDIN te ene cates 6 ptere\nPL Onn ele", "caer a cna! OUuCOMe of relapsing emAting EAE mice treated", "", "", "fon oa Seon! Aa! Lo Sd\n0S a", "eS eee\nweaponsea in RREAE" ]

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[ 1, 1, 1, 1, 1, 1, 1, 1, 4, 5, 2 ]

[ "cae emnenaanasey shor dennasiehadlmnatsirerr! pada namlepred\nEMA was exacted withthe agen RNeasy as taco\nmanure’ structions. RNA preparations were quantified in\nfen NO spectrohotametee a 260 260m abr\nwavlengihs. he RNA spl were conser 10 10D cDNA by\nsingh apasy CDNA eter ans (Apdo\ncoding othe mandate tation Rel tie PCR yen 7200\nApter wee perlaed in 2D} eaton with 2046 (10\nNA equal! af ONA er ec. Cats were nae\nneGAPa beeping ne alcatel celts\nscion titumnikani tects tagion aid ealesotememion", "Oe ee cmotz une Barent pop:\natin athe selected population rom SL (nati 2) the back\n\nround expesion of genes ws sured i hunted MEMSCs\nin eo TO), The AR values for indulge expeson oth\nfen popuaton aT were ven teva 0. Al lative ld\n\ndowtrfogation was taralze wo the pret population TO =\nIn, Ths alowed det compar abe made betwen the ic\n\nrund gene expression te unre parent popultio and ia\nSL sete population 70) as wel asthe gee expression ange\nm cach population in response to'T| surface effects", "ee eee ee Eee eae\nn= 3) thvoughou the stay. Satisalanajss was eafed oa\nsing Students ttt sn CraphPad Dri software (95.04) ih\nSte deen ial othe elec,", "Slaonh-ipr set ceaprihemar- pallonnye-hinialiadedame na reeked\nbaSCs having bee xpeed SV. There were signa ihe\nstaniber of dana calla om sr¥ then am any ether'Wl sorters and TC", "Raedipr yr tegarh pent pine ebeantabieter pennirtiatng ail\namount five cella al saraes compared a3 (ig 30 & te\nspectively). Ths suggests that apoptosis on Ts an inital event\nlowed by asl ecvey a the population theagh ell patie\non he mln recovery eet wa sen he poplin", "an tage aeeeiceaie ta pene ear eenememncnn neneeune aummencinimen onmeemansenea er emetic eaeeneien ar tan treamemrectenel pemaneen temoniouacaneemien ut\npct tons: evans sn ogc recut me vay etic expen eee volo ae ene nd uni van\nYaraclated tack ont Ti surfs sad the varatens i stearic dlrencion were evahuaedy genetic expres of bene plysslgy reed genes and hr", "1\n=\n5\na) &\nsees\npeck", "", "", "3.1. Apoptosis" ]

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[ 1, 1, 1, 1, 1, 1, 5, 2, 2, 2 ]

[ "pr wie ng erg aol ia om Me\nne rr ps hii ina nt anna a\n2013.14 (oy 1. Monthy mean dy pr evopeatin (Epa) ws\nle ding asf the prowing eset al es (ta\ner tha the lng average exept in Febrnry an Mar\n11-12 pd Mare 2008-10.) Wie ad yeas al", "Pi eee ee tie eee see, ie aeek, Wr\nst of fal war uh bighera 3010 (1018s) and wares\naL? 432 ha inate jar ring he ay period\nemai ecg ay een nt al he\ni 1) Tews ge ral isolation as ig\ney prod (i 1) Sala dition a lowe than the lng em\nerage rm hyo Ocak 200910, ly 201011 snd 201213,", "management practices yeled 90 to 0951\" 12-19%) igh\nespecie (se) During aly yea, west lin Sean\naber shon tat of See tin the fe ens (209-10 a", "at in eerie ered ith ine (2A an Deane he\nln Scenaioe 3 an saps) 1. athe ear\nras 1. ite rennin fo yar wth & much higher a\n13-14) ia Year In cmprcn to Sena 1, the elie eli\nrai 2 were mote vale wth ose temps end ih\nnaire ye showed + mail incense with tine (\nue a lope = 0.61) (gah and Relative ir were > 14\nranging fo tA) inal the yeas in Se ad ith\ncise Oe lee", "and inconparuon wih yield Sema (Iles fis Dan\nnce cman fear ping de end of Octobe er\nse rots, tnd inna of pun he tm. Coord\nnario 2 the pe eaten of ld adratnges an consent\na een cod Edens ot een dan Gai ee", "Basly wheat sowing and ZT with residue retention have been re-\nrd ty are gto went by aig he\ntalwinge Singh tly Rey SMA, 20%; Chl a 20410, 8\nesata by Uline Sih (2016) re at wheal", "WDA) ms comperiana wth dae of Seomara 2 doing tn fee tay your Por wend\nsn bor pent oar aw ar a", "sana, snags paid dosing sacasir esinn, al ppmnas eal laa (an agpalont", "witht: ai\n‘ie ene el ee ne\n“cence yi amet", "", "cereus\nPe HEA apo\nep EE", "3.2. Crop and system yields", "", "" ]

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[ 1, 1, 1, 1, 1, 1, 1, 1, 1, 4, 5, 2, 2, 2 ]

[ "tions of mitochondria that occur in some normal cells\nand the morphological changes inthe organelle that ac\ncompany many human diseases, which include myopa-\nhis, diabetes mellitus, liver diseases, neurodegenera\non, aging and cancer [4-8]. However, the changes in\nmitochondrial structuremay be secondary’to (cathe than\ncausing) the alteration in cell performance and precisely\npow changes in mitochondrial structure influence call\njanction in health and disease has neither een confirmed\nnor even demonstrated, Nevertheless, the dynamic r-of-\ngansation of mitochondria and changes in organelles\nStructure must regulate cll function, An understanding\nofthe potential physiological functions to which the\nchanges in mitochondrial arrangement may contribute\nrequires characterisation of the mitochondrial pheno-\nype. In this review the diversity of mitochondrial struc\nsires and dynamics i outlined along with proposed phys\nological roles of the various arrangements,", "Mitochondria have a double membrane arrangement\nwhich separates the organelle into four distinct compat\nments ~ the outer membrane, the intermembrane space,\nthe inner membrane, and the matrix. Each compartment\ncrves dlferent functions, The outer membrane contains\nnumber of porins which permit fre dffeson of mole\ncles into the space between the outer and inner mem.\nbranes. The space between the two membranes (intr\nmembrane space) contains proteins (eg. cytochrome ¢)\nhat play major roles in mitochondrial energetics and\napoptosis. In contrast to the outer membrane, the inner\nmembrane is highly impermeable and most ions and\nmolecules require transporters to cross, The inner mem\nbrane contains a large component (20%) ofthe total mi\nchondrial protein composition, amongst which are\nransporters for carying proteins into the matrix (eg\nransocase of the inner membrane) and the enzymes of\nthe electron transport chain. The matrix contains mos of\nhe enzymes that are responsible forthe citric aid cycle", "cells is only beginning to be acknowledged. Mitochondria\nin fibroblasts are usually long filaments (1-10 ym in\nlength with a fairly constant diameter of ~700 nm),\nwhereas in hepatocytes mitochondria are more uniform:\niy spheres or ovoids [9] In native vascular smooth mus-\ndle, mitochondria ate ovoid or rod-shaped organelles\n[10-13], whereas inthe endothelium a tubular mitochon-\ndrial network exists [14]. Even within individual ells, mi-\ntochondral structure varies. In skeletal muscle, mito-\nchondria are ovoid structures and two populations may\nexist ~ one positioned close tothe sarcolemma, the other\nembedded among the myoibril (15) The subsarcolem-\nma mitochondria ate rounder and smaller than those em-\nbedded among the myofibrils [6]. In pancreatic acinar\ncells there are three different regional groups of uncion-\nlly unconnected mitochondria: one group in the periph-\nral basolateral region close tothe plasma membrane, an-\nother around the nucleus and a third positioned in the\nperiphery ofthe granular region separating the granules\nfom the basolateral area [17]. The three distinet mito-\nchondrial groups may serve varios functions as implied\nby the observation that each groupie activated indepen-\ndently by specific types of cytosolic Ca signals [17] In\ncardiac myocytes there are also three distinct popula-\ntone perinuclear, subsarcolemmal and interibrilla. Mi-\ntochondra in the perinuclear region are more rounded in\nappearance and densely packed than elsewhere [18, 19]", "Beyond the eckuewledgei membrene scrangement,\nthe morphology, and indeed distribution ofthe organelle,\nvaries enormously among cell types. The conventional\nJescription of mitochondrial structure is derived largely\nrom electron microscopy (EM) studies and characterizes\nmitochondria as spherical or short rod structures pos\noned in various parts of the cytoplasm. However, the\nSignificant extent to which mitochondria differ between.", "Together these observations highlight some of the\nstructural diversity and suggest mitochondria are ovoid\nor rod-shaped entities positioned in various parts ofthe\nstoplasm, in broad agreement with conventional EM de-\nscriptions of mitochondria, While the resolution of EM\nhas provided detailed insights into mitochondrial struc\ntare, the disadvantage of EM is that it provides only a\nsnap-shot of the arrangement of mitochondria sta par\nicula fixed point in time. in addition, EM sections ae s0\nthin that the entire mitochondrial morphology cannot be\nunderstood without serial sections andimage reconstruc:\ntion, which is rarely done [16, 20]", "‘More recently, understanding of the structure of mito-\nchondria has been revised with ive cell imaging and the\nproposal that mitochondria exist only as ovoid solitary\nstructures has been challenged [21]. Rather than being\ncitar structures, a single mitochondrion consisting of\n+ continuous mitochondrial reticulum spread theough-\nout the cll hasbeen proposed [22,23]. This single struc\ntare may permit the rapid diffusion of solutes within the\norganelle. Two explanations were put forward to explain\nthe solitary ovoid or rod-shaped appearance ofthe organ-\nele seen itn other investigaticns. First, the solitary appear", "Mitochondrial Morphologies" ]

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[ 1, 1, 1, 1, 1, 1, 2 ]

[ "Jin @ previous publicalion, we reported’ on & series of\nmultiple regression models to elit the variables asec\nted with callers “overall saisiction’ of the helpline\nsevice, Statistical modeling ienied that the mes i\nportant factors aflecting satisfaction related to volunteers\npaving Silent ie to del with the elles’ sues the\nformation being perceived a8 helpfl the volunteer\npcviding the support the callers eddy and for callers\nStal teem Gaeoien col EH", "[In this paper, we present new insights into callers’\nsperiences of breastfeeding helpline suppor. Through\nSymes of the qualitative and descriptive dat, the\nnati interpretations of calle’ experiences ae reported\na iuiinate what and how the telephone support wa\nternalised by callers, andthe potential impact ofthis\nfaopat om take tamatioatias opadencen,", "whuist detailed’ insights into the ‘methodology used\nwithin the eration has been detailed within forme\nssimcatioa [7] cx ultias he ionon ened en Somos,", "A mixed-methoc’ design was used for this study within a\nuctued telephone interview. Whist the enjoy of\nquestions posed during the interview were closed o\nlied Likert scales (eg. calles asked to respond\nstatements using 4 scale of 1 (ery satshed song\ngre) to 5 (very dsatisiedstrongly disagee), daring\nhe interviewer training it was agred that any con\nents or feedback ead by callers during thei response\nthese questions would be recorded on the intervie\norm. These statements explored calles” experiences o\ncessing the Helpline. thei attitudes and. percetved\nimpact of the help and support recved: and to what\nextent the support affected thei wellbelg following the\nall The Interview aio included a number af open ques\nsons to record any enels of contacting the helpline\nwhat was ‘most and Teast helpful aswell as recommen\nfetsoc dex parva dewlaement:", "‘Basic Gemograghic infermetion im melstion bo tgt\nparty, ethniy, marta status were also seconded, 3\nsa ta taht ese eintes oll igen ex tho co,", "fo question wording and sequence of questions rather\noe parenenn ty", "‘The Interview ochedule was Gevelged thaongh 4\nview of previous helpline Mature, aswell as research\nnto breasfeeding. peer support, dscussions withthe\njunders and volunteers who operate the helplines, and\nhe Health Technologies Assesment guidance on the\ndaign and ute of questionnaire [28], The schedule was\neviewed by sbe member of the University of Cental\nLancashice (methodologists (a =2) and research stall\nj2=4)) who have experience in survey development\nundo researehealuation into peer support and was\nsisted with far totems, Hochies secant colatod", "ee ee\neviews. All interviewers were involved In a taining\nvent delvered bythe project lad (GT). The fst thre\nwesks of data collection constituted a pilot phase tore\nfect on the recruitment strategy, sampling plan and\ntervew schedule. Seventy-five interviews were under\nken over this perio, following which minor alterations\nweze made othe schedule io improve cacy and reduce\neptiton. The pot data were included within the fia\neee:", "HERICS approval was obtained’ from the Busy salt baie:\npament, Sport and Health) Ethics Committee at the\nUnivesity f Central Lancashire (Proposal No.7) on\n12\" May, 2011, Ethical sues in tems of informed\nconsent, withdrawal and confidentiality were adhered\nis eect Ads ota", "Over a 14-week period (May~August 2011) all the volun-\ncers operating the helpline asked callers tthe end ofthe\nall whether they would be willing to take part in ate\nphone evaluation Whist heath professionals use the\npelle, a the study almed to elt atts and ef\ncelveness ofthe support and impact om eller outcome,\ndecision was made to only ecu caller wth diet ex\nperience (eq) mothers oe a member of tel personal ne\nwork). Once consent had been provided, the vlunter\ncorded the date and tie of cal the caller's nase, te\none number, which pine they had contacted and\nname of the provider organisation (ABM oe BEN).", "On 8 wee as. FEB Wa = 3) and ev\nsordinatrs contacted all the volunteers in their are,\ntnd recorded all the dete of the callers who had\ngreed to partcgate on a master datasheet, wih al\nmpleted datasheets subsequeatly forward wo the pro\nject lead (GT). Once received, any duplicate deal wer\nmoved though checking the names/eontat deta\nwith previous Ist. It was also decided tha any callers\ntis received more than three weeks after the cll had\npeen made would be removed in order to li cecal\npias. Thete occasions occured when the coordinator\neperienced dificules In contacting volunteers within\nhe agreed weey tine ame. The remaining calle\ntals were then forwarded to the Interviewers. Fo\ntempts were made to contact each calls, a varios\nvaenyatirand", "Bien comtactenis. Une Seller, Wena peovened wae & Ma\nard script that provided Information as to why the", "Methods", "Design and interview\ndevelopment", "Ethics", "", "" ]

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