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However, it is controversial whether progressive hepatic lesions develop in complete abstainers as a result of long-term cyanamide treatment.
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Her course continued to be complicated until consistent follow-up with a nutritionist was established.
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The clinicoradiologic features in this patient were consistent with posterior leukoencephalopathy, which is a rare complication of chemotherapy.
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Lack of experience with patient reporting in real life was one of the main drawbacks in this debate.
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Gastric tumor, endometrial carcinoma and cervical adenocarcinoma in situ were detected after treatment with tamoxifen for breast cancer.
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The results thus far are very encouraging and the study is being continued.
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CONCLUSIONS: Carboplatin desensitization can be successfully performed on an outpatient basis with close observation and cardiorespiratory monitoring.
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Two patients with ovarian cancer who had received multiple courses of cisplatin without complications experienced hypersensitivity reactions to cisplatin: one, involving intrahepatic artery infusion, manifested general erythema, dyspnea, and hypotension; the other, involving intravenous infusion, manifested abdominal pain, general erythema, and fever.
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Four patients were treated with acyclovir, but three were given suboptimal doses.
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Thus, troglitazone should be prescribed with caution and should not be used as a first-line agent in the treatment of type II DM when potentially less toxic alternatives are available.
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The leukoencephalopathy, documented clinically and by CT and EEG, cleared after 2350 mg of leucovorin (citrovorum factor, folinic acid) was given in addition to the 135 mg given as part of the therapy.
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Carbamazepine toxicity following Oxybutynin and Dantrolene administration: a case report.
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OBJECTIVES: The improvement of pre-existing inflammatory bowel disease after orthotopic liver transplant might be anticipated.
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OBJECTIVE: To report a case of calcineurin-induced pain syndrome (CIPS) in a child undergoing his second hematopoietic stem cell transplant (HSCT).
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Von Willebrand's disease has been established as the most common hereditary hemorrhagic disease.
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To date, eight cases of TEN and one of SJS related to lamotrigine administration have been reported in the literature.
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We hypothesize that during interferon therapy, melanocytes may produce more melanin pigment in the presence of alpha-melanocyte stimulating hormone and sufficient amounts of tyrosine, leading to melanin deposits and clinical hyperpigmentation.
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Angioimmunoblastic lymphadenopathy with dysproteinemia following doxycycline administration.
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We describe a patient with the antiphospholipid syndrome who had skin necrosis develop from low-molecular weight heparin therapy at sites distant from injection sites.
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Impairment of consciousness developed with a remarkable temporal delay of 24 to 48 hours after occurrence of peak serum concentrations and resolved with a comparable delay after reaching the therapeutic range (anticlockwise hysteresis).
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We introduce a case of a sixty years old woman with several previous episodes of rhinitis, conjunctivitis and perspiration immediately after the administration of salmon calcitonin with nasal spray or intramuscular administration (Calsynar).
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Recent studies show that patients with other injury patterns do not appear to have significant differences post trauma, although the data about such outcomes is sparse.
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Minimal change nephrotic syndrome after allogenic hematopoietic stem cell transplantation.
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We calculated the changes in alpha(1)-adrenoceptor occupancy by endogenous norepinephrine during treatment with the usual doses of milnacipran, fluvoxamine and imipramine by using pharmacokinetic and pharmacodynamic parameters obtained from the literature.
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The neuropathologic findings in these cases, although similar, varied in severity and distribution.
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High-dose tamoxifen in treatment of brain tumors: interaction with antiepileptic drugs.
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It is suggested that the patient had sulfasalazine-induced lupus, which manifested with serositis and pulmonary parenchymal involvement in the absence of joint symptoms.
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OBJECTIVE: To report a case of significant hepatic and renal failure with the use of argatroban in a patient with heparin-induced thrombocytopenia (HIT) requiring continuous veno-veno hemodialysis (CVVHD).
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Patient ages ranged from 19 to 36 years at the time of diagnosis of their Crohn's disease, and all were white.
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The children were symptom-free at follow-up, which ranged from 5 months to 3 years.
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Possible mechanisms for damage to the urothelium by ketamine are suggested.
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Crumley).
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Interferon-alpha (IFN-alpha) may precipitate or exacerbate the occurrence of MPGN.
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The authors describe valproate-induced hyperammonemia and mental status changes in an 88-year-old man, the first known reported case in an elderly patient.
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Care should be taken in prescribing antipsychotic drugs to patients who are prone to cardiovascular side effects, and alternatives to antipsychotics with prominent anticholinergic profile, in particular, should be sought.
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Three patients were treated with aminocaproic acid for medically uncontrolled hyphemas that developed after cataract extractions.
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Although some reports suggest that treatment with recombinant erythropoietin may affect A1C values in patients undergoing hemodialysis, we know of no evidence to support this interaction in patients with chronic renal insufficiency who are not undergoing hemodialysis.
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The remainder of the procedure was uneventful.
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Priapism as a complication of heparin therapy.
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Phenytoin and carbamazepine were necessary to control the seizures.
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Pyogenic portal vein thrombosis as a reservoir of persistent septicemia after cyanoacrylate injection for bleeding gastric varices.
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Severe granulomatous inflammatory response induced by injection of polyacrylamide gel into the facial tissue.
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The diagnosis was based on the rapid onset of renal failure, presence of eosinophilia, skin rash, and characteristic renal biopsy finding, following the administration of ampicillin.
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Therapy with IFN-beta has rarely been associated with the development of autoimmune disorders.
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Although combinations of belladonna, ergotamine, and phenobarbital have been used for medical treatment of menopausal symptoms since the 1960s, this is the first known case report of its association with anticonvulsant hypersensitivity syndrome.
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After 1 week of nefazodone therapy the patient experienced headache, confusion, and "gray areas" in her vision, without abnormal ophthalmologic findings.
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We reviewed all cases of RS reported to the Michigan Department of Public Health during 1982 and 1983.
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However, increasing the indometacin dose to 4 mg/kg/day improved their growth significantly, without changing their symptoms or biochemistry.
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For nearly half a century, FMF was thought to cluster primarily in non-Ashkenazi Jews, Arabs, Armenians, and Turks, although the screening of the 8 known mutations in an American cohort has identified substantial numbers of people from the Ashkenazi Jewish and Italian populations in the United States who also have this disease.
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Familial Mediterranean Fever (FMF) is an inherited disease, closely following the pattern of autosomal recessive inheritance.
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PURPOSE: To report a case with concentric retinal pigment epithelium (RPE) atrophy after a single photodynamic therapy (PDT).
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We present the case of a 75-year-old man with ankylosing spondylitis who developed surgically induced necrotizing scleritis (SINS) more than 3 years after uneventful extracapsular cataract extraction and posterior chamber intraocular lens implantation.
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The day after clozapine was stopped, while he was still receiving clomipramine 150 mg/d, he began behaving oddly, started sweating profusely, shivering, and became tremulous, agitated, and confused.
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Most antidepressants and also antipsychotics are metabolized by the polymorphic debrisoquine/sparteine hydroxylase, i.e., cytochrome P450 (CYP)2D6.
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Through November 30, 2004, the FDA received 6 reports of DIC associated with "acute hemolysis" (or similar terms), 5 of which involved fatalities.
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We describe four patients who had seizures while receiving ofloxacin; no other causes were evident.
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Loiasis, caused by the filarial parasite Loa loa, is endemic in West and Central Africa.
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Cardioembolic stroke, early anticoagulation, and brain hemorrhage.
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The authors report 2 cases of renal damage associated with lithium carbonate treatment.
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A 22 year old female was admitted to hospital two hours after ingesting 4 g of dapsone.
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The authors describe a case of combined lithium and haloperidol toxicity characterized by hyperpyrexia, severe rigidity, mutism, and development of irreversible tardive dyskinesia.
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Using insulin's ability to promote fat and protein synthesis is a simple and effective way of treating atrophied scars.
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Adverse effects of amiodarone including pulmonary toxicity, hepatotoxicity, aggravation of arrhythmia, and thyroid diseases are well understood.
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Thiazide-induced hyponatremia.
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Two patients treated for chronic myeloid leukemia with high doses of CCNU (1100 mg/m2 and 1240 mg/m2, respectively) developed a fatal pulmonary fibrosis.
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RESULTS: A clinical diagnosis of fixed drug eruption owing to use of the PDE5 inhibitor tadalafil (Cialis) was made.
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In view of the potential hazards of tissue plasminogen activator, close pediatric ICU monitoring is indicated with the use of high-dose tissue plasminogen activator infusions.
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Histopathologic examination and direct immunofluorescence test were consistent with IgA bullous dermatosis.
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Within 6 weeks, endophthalmitis resolved in three consecutive patients with positive aqueous cultures.
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We present a case of interstitial pneumonitis and diffuse alveolar hemorrhage, which represents the second such case reported in the literature.
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The first patient was supported by the use of a paracorporeal air-driven left ventricular assist device of the NCVC type, and had a moderate degree of renal and hepatic dysfunction at the time of transplantation.
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When cyanamide-treated alcoholics relapse into drinking, more severe inflammation develops in the liver.
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All patients had inadequate ACT measurements, despite conventional heparin dosage and ongoing clopidogrel treatment.
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Acute INH toxicity should be suspected in children presenting with seizures with or without fever.
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Prenatal cytomegalovirus (CMV) infection associated with severe brain damage was detected in an infant whose mother had been treated with prednisolone and azathioprine for systemic lupus erythematosus (SLE).
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A 36-y-o patient with schizophrenia, who had consumed gradually increasing quantities of oolong tea that eventually reached 15 L each day, became delirious and was admitted to a psychiatric hospital.
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About 7% of Caucasians are poor metabolizers (PM), and such patients might develop adverse drug reactions when treated with recommended doses of, for example, tricyclic antidepressants.
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BACKGROUND: Uterine malignant mixed mesodermal tumor is a rare variant of uterine cancer.
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Twenty-five (86%) patients had initial visual acuity of less than 20/60.
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Analysis of a phenotyped human liver bank revealed that the antibodies recognised a 52.5 kDa microsomal protein which exhibited marked heterogeneity in its expression and appeared to be regulated co-ordinately with human CYP2C8 and 3A3/4.
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We report four patients, three of whom first developed psoriasis and one who had an aggravation of the condition during treatment with interferon-alpha.
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The infant developed repeated tongue thrust, abnormal hand posturing, and tremor of all extremities.
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Meperidine-associated central nervous system (CNS) excitatory toxicities are believed to be caused by accumulation of the active metabolite normeperidine.
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We reported 3 patients who developed acute generalized dystonia and akinetic rigid syndrome following an initial therapy with d-penicillamine 125-500 mg daily.
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RESULTS: Intradermal tests to intravenous cyclosporine formulation (1 mg/mL) were positive in the patient and negative in two controls.
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Treatment of iron overload in adults with continuous parenteral desferrioxamine.
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Four patients who manifested symptoms of the antiepileptic drug (AED) hypersensitivity syndrome during therapy with carbamazepine are reported.
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A 5-month-old infant became lethargic and poorly responsive after receiving 1 drop of brimonidine in each eye.
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We then review case reports, expert opinion, and manufacturer recommendations regarding hepatitis B viral infection, TNF-alpha, and TNF-alpha inhibitors.
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A total of 311 patients (35.5%) had at least one small intestinal resection.
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Case report and literature review.
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CASE SUMMARY: An 84-year-old woman presented to the emergency department with a bilateral cervical hematoma and symptoms of upper-airway obstruction that had been increasing for 72 hours, with dyspnea and difficulty speaking developing in the previous 24 hours.
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During clarithromycin coadministration, four out of the seven patients developed moderate-to-severe toxic symptoms of carbamazepine, such as drowsiness, dizziness, and ataxia, which resolved within 5 days after clarithromycin discontinuation.
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Pathological examination of both resected femoral heads showed no intravascular thrombosis.
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A case report of treatment with intra-arterial urokinase and review.
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He was administered insulin immediately, however, his fasting plasma glucose level remained unstable despite the insulin treatment.
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Once regarded as fatal not many series of patients with ITO have been reported with the long follow up as in the present case.
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CT scan of the abdomen disclosed a huge abscess in the right lobe of the liver.
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A case of immunosuppressive measles (rubeola) encephalitis in a 12-year-old boy in remission from acute lymphoblastic leukemia is described.
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We suggest that dapsone is an effective second-line agent in the treatment of rheumatoid arthritis.
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