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Atrial fibrillation occurring in a patient taking etanercept plus methotrexate for rheumatoid arthritis.
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Stent-grafts were constructed from Z stents covered with polyester fabric and were delivered remotely through a catheter under fluoroscopic guidance.
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Moreover, treatment with immunosuppressive drugs such as cyclosporine, cisplatin, tacrolimus, and interferon-alpha can induce a condition resembling RPLS.
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She received 5-fluorouracil, doxorubicin, and cyclophosphamide.
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B-cell lymphoproliferative disorders are rare but serious complications of solid organ and bone marrow transplantation.
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Successful treatment of rhegmatogenous retinal detachment secondary to globe perforation during peribulbar injection in a case of sympathetic ophthalmia.
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She was treated with subcutaneous twice-daily danaparoid (Orgaran) for the remainder of the pregnancy, achieving anti-Xa levels in the therapeutic range 0.5-1.0 IU/ml.
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This article reviews the results of all cases of C-TMA reported to date in the English literature and discusses the theories of pathogenesis, clinical features, treatment, and treatment-related complications of the syndrome.
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They require immediate discontinuation of the drug and a washout procedure to hasten drug elimination from the body.
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Both patients presented with abdominal pain and turbid dialysis effluent with or without fever.
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Early detection of such hearing loss is important for providing management options.
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Three Alzheimer's disease patients with Pisa syndrome were presented.
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Drug-induced immune hemolytic anemia (IHA) is rare but is being reported with increasing frequency.
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DISCUSSION: Patients with 5-FU-induced ectropion experience tender, red, scaled lids, making contact lens wear difficult.
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We report 5 patients (3 patients with chronic hepatitis C treated with pegylated interferon alfa-2b in association with oral ribavirin and two patients with chronic myelocytic leukemia) who developed local cutaneous reactions at sites of injection after the administration of weekly subcutaneous injections of pegylated interferon alfa-2b at different doses.
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Hydrocortisone prophylaxis and verapamil therapy were the primary therapies used in patient 1 (the only survivor).
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At the time of deterioration all three had reduced HIV viraemia and increased CD4 cell counts.
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Toxic epidermal necrolysis resulted after 19 days of treatment with 5-fluorocytosine and amphotericin B.
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An issue under much clinical debate is whether treatment with two antipsychotic agents simultaneously is advantageous for optimizing response in patients whose previous monotherapy with antipsychotic agents has failed.
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We describe the development of ischemic colitis in a woman who was treated with tegaserod and review the relationship among ischemic colitis, tegaserod use, and irritable bowel syndrome.
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Sweet's syndrome is an acute febrile neutrophilic dermatosis that is a known complication of the administration of filgrastim, a drug that causes increased neutrophil proliferation and differentiation.
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He has not had any further episodes of thrombocytopenia to date.
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The fifth patient experienced nausea and discontinued treatment after 4 weeks.
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Until recently, discontinuance of anticoagulant therapy has been recommended, as this cessation has been shown to slow or halt further tissue infarction.
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Used injudiciously, naloxone can lead to withdrawal syndrome, return of severe pain, and other adverse effects.
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Anti-thyroid Abs were found positive.
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A 53-year-old man developed lower leg edema 4 weeks after rosiglitazone was increased from 4 mg once/day to 4 mg twice/day.
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Intracranial hemorrhage and focal seizures secondary to use of L-asparaginase during induction therapy of acute lymphocytic leukemia.
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Considering the possibility of this diagnosis in patients developing confusion and neurological degradation with respiratory alkalosis after intensive chemotherapy, could allow earlier treatment and perhaps improved survival.
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We reported a case of disulfiram-induced hepatitis with unique clinical features and compared our case with others in the literature.
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In August 2005, he was admitted to a medical facility in the local community with upper gastrointestinal bleeding, and received several units of blood and blood products.
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Radiation recall from gemcitabine is rare, but can potentially arise in any site that has been previously irradiated.
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Therapy-related myelodysplastic syndrome with der(17)t(12;17)(q13;p13) as a new recurrent cytogenetic abnormality after treatment for chronic lymphocytic leukemia.
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Her condition stabilized during treatment with intravenous heparin, aspirin, nitrates, beta-blockers, digoxin, ACE inhibitor and anticoagulants.
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The patient made a full neurologic recovery and remains free of disease recurrence 21 months after treatment.
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Each procedure reduced the serum level of intercellular antibodies by 50% to 87%.
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Eight deaths that occurred during Upjohn-sponsored clinical trials of topical minoxidil and two deaths in subjects who used extemporaneous formulations of the drug are summarized.
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These effects can increase the likelihood of its aspiration and subsequent impaired clearance from the respiratory tract.
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Acute tumour lysis syndrome (TLS) is a catastrophic complication of the treatment of certain neoplastic disorders.
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Also to be considered in the differential diagnosis are multifocal infection and polysynovitis/arthritis of other etiology.
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The following is a report of 2 cases of rifampicin-induced renal insufficiency.
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A patient was admitted to the intensive care unit because of respiratory failure, and warfarin therapy was started at 2 mg/day for the treatment of pulmonary embolism, together with other medications.
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There have only been three reports of Mycobacterium chelonae prosthetic infection of which two cases were associated with total hip arthroplasty and one with total knee arthroplasty and no reports of both Mycobacterium tuberculosis and M. chelonae occurring in the same joint.
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Transient acute myopia resulting from isotretinoin (accutane) therapy.
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Valproate elimination was enhanced by the continuous infusion of activated charcoal.
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Local control of tumor with preservation of organ function was achieved.
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We report the case of a 69-year-old patient with metastatic renal clear-cell carcinoma, treated with nephrectomy and three lines of therapy (interleukin-2 plus interferon-alpha2a, vinorelbine plus gemcitabine, and capecitabine), who started a fourth-line therapy with oral sunitinib because of disease progression.
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Bisphosphonate-related osteonecrosis of the skull base.
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She was successfully treated with intravenous cefoxitin and removal of the indwelling central catheter.
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The daily doses ranged from 0.5 to 3 mg.
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Psoriasis triggered by toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors.
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The patient had a favourable outcome.
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We report 4 patients with involvement of 5 hips with septic arthritis in established osteonecrotic joints.
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RESULTS: A total of 97% were removed after completion of chemotherapy, and 3% because of sepsis or malfunction.
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There are major side effects of anastrozole including decrease in both lumbar spine and total hip bone mineral density, increase in the incidence of all bone fractures (especially fractures of spine, hip and wrist), joint disorders and increase in the cholesterol level.
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The first patient developed a monoarthritis 2 weeks after initiation of IFN-beta, which persisted during the 14 months of therapy and resolved with discontinuation of the medication.
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Experimental evidence indicates that corticosteroid administration causes a reduction in T lymphocytes mediated by suppression of cytokines.
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Indometacin is reported to improve growth in Bartter syndrome, but not in Gitelman syndrome, where magnesium supplements are recommended.
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In addition to being used as adjuvant chemotherapy, S-1 is a promising agent for palliative treatment.
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However, raising the dose increases the likelihood of side effects and may significantly compromise patient compliance.
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Awareness of this unusual entity will help to avoid misdiagnosis of malignancy or unnecessary thoracotomy.
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Controversy exists as to whether making a definitive diagnosis in these patients has an impact on overall outcome.
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At its peak the daily protein loss was 35.82 g.
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Two cases of malignant hyperthermia (MH) are presented.
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We also review the literature describing the spectrum of clinical findings due to intraocular blastomycosis.
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The clinical presentation was disseminated varicella infection with multiple organ involvement.
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During the first days of arsenic trioxide treatment a rapid decrease in the D-dimers was seen (normal values reached until day 7), together with a slight decrease in peripheral blood leukocytes.
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Neutrophilic eccrine hidradenitis mimicking cutaneous vasculitis in a lupus patient: a complication of cyclophosphamide.
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Arginine has been shown to shift potassium from cells to the extracellular compartment, an effect directly related to its serum concentration.
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Sibutramine, a serotonin reuptake inhibitor, currently is used in treatment of obesity.
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Of the four patients who responded to HU with an increase in total Hb, all reported symptomatic improvement and three have not required further transfusions.
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Scans were performed without opioid drugs and 30 minutes after intramuscularly administered meperidine, morphine, hydroxyzine, hydroxyzine plus meperidine, butorphanol, and nalbuphine.
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In addition, patients with blebitis should be observed closely to identify extension into the vitreous cavity so that intravitreous antibiotics can be administered in a timely fashion.
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The neurological complications may be reduced by earlier recognition and better understanding of their etiopathogenesis.
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CASE SUMMARY: A 57-year-old female with cardiomyopathy and "sulfa" (trimethoprim/sulfamethoxazole) allergy documented as pancreatitis presented with symptoms consistent with pancreatitis after use of furosemide.
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METHODS: The human leukocyte antigen (HLA) typing of peripheral leukocytes was studied by lymphocytotoxicity technique.
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A case of acute respiratory failure due to diaphragmatic weakness following adalimumab therapy for psoriasis is described.
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CASE SUMMARY: A 39-year-old white Jewish schizophrenic man treated with olanzapine developed an elevated serum CK concentration with a peak concentration of 4000 IU/L (normal < 230).
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Although gabapentin withdrawal has been previously reported and usually consists of anxiety, diaphoresis, and palpitations, this is the first reported patient with generalized seizures and status epilepticus secondary to gabapentin withdrawal.
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METHODS: A patient who developed dramatic, permanent vision loss after a 9-month course of treatment with ethambutol and isoniazid for pulmonary tuberculosis is presented.
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METHOD: A patient with acquired immunodeficiency syndrome (AIDS) with pulmonary Pneumocystis carinii was treated with 750 mg of atovaquone three times a day.
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Unfortunately, not all patients respond to these treatments.
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A Group IVC AIDS patient experienced repeated methicillin-resistant Staphylococcus epidermidis colonization and infection of his central venous access device.
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We describe a patient with metastatic prostate cancer who developed nonoliguric renal failure during treatment with suramin.
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We postulate that the bolus of sulprostone resulted in possible coronary spasm that resulted in cardiac arrest.
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We review the pathophysiology of prophylaxis-related encephalopathy in leukemia patients and summarize its clinical, histological, and radiological characteristics.
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Although she immediately improved following abortion (within 2 hr, peak airway pressure fell from > 70 to 38 cmH2O, without change in plateau pressure), superimposed morbidities improved more slowly, and the patient made a complete recovery.
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Since no satisfactory remission was achieved using a multi-drug chemotherapy protocol that included cyclophosphamide, vincristine, cytosine arabinoside, prednisolone, and subsequently supplemented by L-asparaginase, it was replaced by another protocol combining vincristine, L-asparaginase, prednisolone, cyclophosphamide and doxorubicin.
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Although its side effects are few, tamoxifen increases the incidence of proliferative lesions of the endometrium, which theoretically should be preventable with progestational agents.
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The individual drug responses vary and no recommended standard doses exist.
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The most common symptom was pain (93%).
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Analeptic-induced paranoid psychosis occasionally occurs in the treatment of narcolepsy.
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Complete dissolution was achieved with a combination of i.v. tissue plasminogen activator and heparin.
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Subsequent observation revealed the presence of choreiform movements.
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An unusual case of chronic coronary artery dissection: did cisplatin play a role?
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We present a retrospective analysis of 4 HSCT recipients who survived long-term artificial respiration subsequent to pulmonary mycosis, and compare our current findings with historic data.
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Discontinuation of MMF was followed by a rapid and spontaneous rise in neutrophils in two patients.
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There is evidence that the angiotensin II receptor antagonist, losartan, increases urate excretion by reducing reabsorption of urate in the renal proximal tubule.
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Portal vein thrombosis was diagnosed in 2 patients.
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Post transplant lymphoproliferative disorder (PTLD) involving the brain was seen in 2% of the liver allografts, 3% of the heart, and 7% of the heart-lung recipients.
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