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Fatal outcome of intravesical formalin instillation, with changes mimicking renal tuberculosis.
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The septal defect, repaired surgically by Hazeltine's method healed completely within 6 weeks.
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There are now reports of liver failure following treatment of childhood cancers with AMD.
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After standard treatment had failed, we tried to treat the patient by administering rituximab directly into the cerebral ventricle through an Omaya reservoir, in addition to conventional intrathecal and systemic chemotherapy.
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IMPLICATIONS FOR NURSING PRACTICE: Nurses must understand the pharmacology, mechanism of action, clinical presentation, potentially lethal risks, and traumatic psychosocial stresses experienced by DPD-deficient patients with cancer receiving 5-FU therapy in order to develop timely interventions and alternative plans of care.
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It can also be found in the United States, where illegal sales have been reported in California gift shops, markets, bakeries, and other retail establishments.
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Since the thrombocyte count started to increase immediately after initiation and dropped immediately after discontinuation of ciprofloxacin and tazobactam/piperacillin and all other drugs were discontinued already before or were started after the nadir of the thrombocyte count, these two antibiotics were regarded causative.
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Three days after stopping the infusion she collapsed and died.
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Adrenal crises in children treated with high-dose inhaled corticosteroids for asthma.
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We suggested that colchicine should be used with caution in the presence of renal failure especially when other drugs which affect the metabolism of colchicine are also prescribed.
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His serum calcium returned to a normal range in three months with Vitamin D and calcium supplement.
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Objective improvement of tremor after use of metoprolol was documented by accelerometry.
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Findings from biopsy specimens of skin and jejunum suggested a cell-mediated pathogenesis, and lymphoproliferative studies of the patient's mononuclear cells revealed a positive response to phenobarbital.
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Uniquely, however, relief of peptic symptoms induced by hypergastrinemia is now available from acid-suppressive drugs such as proton-pump inhibitors (PPIs).
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This rare association suggests that oral hormone replacement therapy poses a risk of thrombosis especially in patients with cc-TGA after prosthetic valve replacement.
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Cyclosporine is a potent inhibitor of simvastatin metabolism, and may therefore facilitate simvastatin-induced rhabdomyolysis.
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To the best of our knowledge, corneoscleral melting in the first postoperative week after a single intraoperative application of mitomycin C has not been reported.
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This patient recovered after aggressive supportive therapy including intravenous alkali and fluid administration as well as continuous venovenous hemodiafiltration.
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Streaky pigmentation in a patient with acquired immune deficiency syndrome (AIDS).
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Liver biopsy was consistent with a drug-induced intrahepatic cholestatic reaction.
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Urine volume ranged from 1,640 to 2,260 mL/24 hr, and serum creatinine level rose from 2.3 to 8.3 mg/dL.
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We report a rare case of colonic mucosal necrosis following Kalimate (calcium polystryrene sulfonate), an analogue of Kayexalate without sorbitol in a 34-yr-old man.
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Localized panniculitis and subsequent lipoatrophy with subcutaneous glatiramer acetate (Copaxone) injection for the treatment of multiple sclerosis.
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A 69-year-old type 2 diabetic man was admitted due to diabetic gangrane.
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Etoposide is an important component of current HLH treatment regimes.
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The reporting rate for angioedema was calculated to be 9.8 cases per 1,000,000 pediatric patients.
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The epiphyseal myeloid cells were reduced or sometimes eliminated during id injection.
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Neurotoxicity can occur at any time using high-dose cytosine therapy.
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A toxic encephalopathy characterized by depressed level of consciousness, marked irritability, and ataxia developed in seven children, 5 years of age and younger, following administration of an antiemetic combination of pentobarbital and pyrilamine maleate.
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A patient presented with lactic acidosis and severe acidemia; sodium bicarbonate was administered to titrate the very large hydrogen ion load.
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She developed large swellings in both sides of her lower abdomen.
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In a series of 104 cases of intentional or inadvertent use of zidovudine at differing gestations in pregnancy, there were eight spontaneous first trimester abortions, eight therapeutic terminations, and eight cases of fetal abnormality occurring among a total of 88 cases where the pregnancy progressed.
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Screening serologic tests for autoantibodies including antinuclear antibodies, antidouble-stranded DNA, anti-SS-A, anti-SS-B and anti-Sm were all negative.
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Patients treated with captopril who develop "atypical cholangitis" should be suspected of having captopril-associated liver damage.
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OBJECTIVE: To report a case of serotonin syndrome associated with interaction between fentanyl and citalopram, as evidenced by medication history, clinical features and reversal following discontinuation of fentanyl.
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If associated with a prolonged QT interval, it is called torsades de pointes.
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We discuss how these patients management differs from other intensive care unit patients with CLS and how it is important to diagnose this condition early in haematological oncology cases.
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Scleromyxedema in a patient with multiple sclerosis and monoclonal gammopathy on interferon beta-1a.
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We describe a detailed case of fulminant hepatitis induced by nevirapine (Viramune) and treated by liver transplantation.
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Patients receiving amifostine who develop only fever should be evaluated for an adverse drug reaction, as well as for sepsis and fevers of neutropenia, and it may be necessary to discontinue the drug.
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Endogenous pneumococcal endophthalmitis after splenectomy: report of two cases.
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One patient was treated with amphotericin B and his central venous catheter was removed, but he died of Klebsiella pneumoniae bacteremia.
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CONCLUSIONS: Any patient undergoing medical treatment for tuberculosis requires proper education concerning potential drug side effects.
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It was presumed that the upbeating nystagmus in this case was elicited from the lesion of the anterior vermis of the cerebellum and/or its connections.
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Two of these patients, who also received the anti-emetic prochlorperazine, lost consciousness for 48-72 h and then fully recovered.
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Interstitial granulomatous dermatitis associated with darifenacin.
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After using the antibiotic lock technique, the patient maintained his catheter without further infection for an additional 2 months.
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Two animals were injected with balanced salt solution as controls.
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The frequency of compensatory hyperhidrosis often reflects the extensiveness of the denervation.
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In 3 dogs scheduled for surgical removal of cataracts, systemic and topical treatment with antibiotics and topical ocular treatment with prednisolone, atropine, flurbiprofen, and phenylephrine were used to achieve maximal mydriasis, with minimal risk of pupillary constriction in response to surgery.
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We suggest adding this side effect to the list of untoward effects of lidocaine and to the differential diagnosis of fixed dilated pupils in neonates treated with lidocaine.
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Tamoxifen has proved efficacious in all settings of breast cancer.
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These findings strongly support the hypothesis that pulmonary capillaritis may represent a form of acute humoral rejection in the lung allograft that is less common than, and clinically and histologically distinct from, typical acute cellular rejection.
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This adverse reaction is more common in children than adults and is rarely symptomatic.
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A 77-year-old woman was urgently admitted for the treatment of diabetic ketoacidosis and a duodenal ulcer hemorrhage in March 1999.
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CD3/CD4 T-helper lymphocyte count showed a significant decrease immediately after LT which rapidly recovered after initiation of HAART.
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An individualized approach must consider local resources, the patient's age and prognosis, type of immunosuppression, opinions of patient and family regarding invasive measures and heroic support, and previous patterns of infection in the institution.
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It appears to be selectively protective to salivary glands and kidneys without being tumor protective.
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The favourable outcome in these two patients contrasts with the fatal outcome of the two other reported cases of nitrofurantoin induced BOOP.
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CONCLUSION: The new quinolone derivatives (levofloxacin, sparfloxacin, grepafloxacin, trovafloxacin, gatifloxacin and moxifloxacin), also called gyrase inhibitors, are known for their potential to cause central nervous system-related adverse effects, including headache, dizziness and insomnia.
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Hypersensitivity to aspirin can be manifested as acute asthma, urticaria and/or angioedema, or a systemic anaphylactoid reaction.
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Growth and spread of malignant cells within the stagnant dilated lymphatics are the likely cause of the characteristic nodular dissemination of the tumor in a lymphedematous extremity, regardless of the type of neoplasm.
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Besides those manifestations, the patient also showed mucocutaneous lesions that were both clinically and histologically indistinguishable from those of pustular psoriasis.
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Doxorubicin cardiotoxicity: possible role of digoxin in its prevention.
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Complete seizure control was achieved but the patient developed hallucinations, agitation and self-harming behaviour, as well as poor social contact.
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Twenty-nine patients reported spontaneous pain; a variety of other paresthesialike sensations, e.g., tingling, numbness, and formication, occurred in 32 patients.
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An analysis of the literature shows that perfusion, usually combined with excision, seems to give definitely better results than surgical excision alone.
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This is an image and brief case report of a 13-year-old boy who presented with severe rash and systemic symptoms after starting oxcarbazepine.
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RESULTS: Ten eyes in 6 patients with late-onset interface inflammation and increased intraocular pressure were identified.
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We believe that these skin eruptions belong to a spectrum of neutrophilic dermatoses that can be induced or aggravated by G-CSF therapy.
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The nesiritide treatment duration was longer for this patient than the 45 days previously reported in a pediatric patient.
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Thoracic CT showed a markedly enlarged mediastinum, with a voluminous mass in the middle mediastinum.
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Prior neurologic illness and the syndrome of irreversible lithium-effectuated neurotoxicity (SILENT).
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Many pus cells and a few red blood cells were detected in the patient's stool, but the results of a stool culture for bacteria were negative.
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Nitrogen-oxygen saturation therapy in serious cases of compressed-air decompression sickness.
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These three cases illustrate the diagnostic and therapeutic overlap between childhood and adult anxiety disorders and indicate the need for empirical studies aimed at evaluating diagnostic and treatment issues in childhood anxiety disorders.
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Immune-mediated reactions to nonsteroidal anti-inflammatory drugs (NSAIDs) are unusual, and true allergy to the drug flurbiprofen has never been documented.
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G-CSF (50 micrograms/m2/day, subcutaneous injection) was administered simultaneously with a continuous intravenous infusion of Ara-C (70 mg/m2/day).
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Pharmaceutical drugs, industrial compounds, and inhaled particles have been implicated as causative agents.
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Using an illustrative case this article examines the prognostic significance of gastrointestinal haemorrhage and the risk of stopping anti-platelet therapy.
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Although a few case reports link metronidazole with the development of pseudomembranous colitis, albendazole has not been associated with the development of this condition.
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The infant had growth retardation and multiple anomalies including microbrachycephaly, coronal craniosynostosis, hypotelorism, shallow orbits, proptosis, blepharophimosis, small, abnormal ears, unilateral preauricular pit, broad, flat nasal bridge, microstomia, high-arched palate, micrognathia, preaxial upper limb and postaxial lower limb defects consisting of hypoplastic thumbs, and bilateral absence of the 4th and 5th toes.
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An understanding of the proposed pathophysiology of various types of delirium will allow appropriate clinical measures to be taken.
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Final treatment plans for the HNCP should include medical assessment of past dental history, oral hygiene, potential compliance, or lack of, to dental care recommendations, the emotional state of the patient, socio-economic status of the patient (lifestyle, cost of care), future quality of life, the medical and/or life prognosis of the patient.
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After three cycles of chemotherapy over a 10-week period, the patient's dosage requirements returned to her baseline level (before treatment with 5-fluorouracil and leucovorin had started).
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Severe abdominal pain in low dosage clofazimine.
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Five of the patients had D-Dimers levels measured, all were elevated.
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Bronchial anthracostenosis describes a disease entity consisting of bronchial destruction, deformity and stenosis related to dark pigmentation on bronchoscopy in patients with a history of coal workers' pneumoconiosis or chronic exposure to biomass smoke.
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He recovered well and was able to walk by postoperative day 4.
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Staphylococcus lugdunensis endocarditis following cardiac catheterisation.
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Weight loss during therapy with olanzapine orally disintegrating tablets: two case reports.
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In the untreated infant with Menkes Kinky Hair Syndrome, copper concentrations in brain and liver are deficient, while excessive copper accumulates in other tissues.
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In a postural challenge test after administration of isosorbide dinitrate (5 mg), blood pressure decreased from 120/67 to 65/35 mmHg, followed by syncope with a sudden decrease in pulse rate from 85 to 60 beats/min.
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This case, in which continuous morphologic adaptation of the cornea occurred, indicates that observation, rather than intervention, is a valid therapeutic option for stage 4 DLK.
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Occurrence of withdrawal dyskinesia indicates that the neuroleptic effects of amoxapine may be clinically significant.
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Medical practitioners are also applying recombinant factor VIIa toward the control of bleeding in patients without hemophilia.
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CASE SUMMARY: A 10-year-old white girl with bilateral optic glioma developed a hypersensitivity reaction to carboplatin after nine courses.
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When patch test are performed with several drugs of the same family, results seem to indicate an absence of cross-sensitivity, but in several patients, oral provocation test were needed because patch test gave no conclusive information.
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We reported 3 patients who developed acute generalized dystonia and akinetic rigid syndrome following an initial therapy with d-penicillamine 125-500 mg daily.
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No changes in respiratory/hemodynamic status or oxygen saturation were observed.
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