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We report a case of a 60-year-old woman affected by squamous lung carcinoma, who developed paroxysmal supraventricular tachycardia during cisplatin and etoposide combination chemotherapy.
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Immunosuppressive treatment of rippling muscles in patients with myasthenia gravis.
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Usually, these patients develop hepatitis B surface antigen (HBsAg) seroreversion during the flare.
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A 52-year-old, white female developed low-grade fever, cough, and dyspnea after 8 weeks treatment with sodium aurothiomalate for rheumatoid arthritis.
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Post-transplant lymphoproliferative disorder following cytomegalovirus reactivation in a lung recipient.
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The subjects were confined to female patients to exclude patients with potential prostate hypertrophy.
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Splenic hemorrhage: a complication of tissue plasminogen activator treatment.
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Ruptured Meckel diverticulum mimicking mucositis in a patient receiving induction therapy for high-risk acute lymphoblastic leukemia.
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Neuroleptic-induced "painful legs and moving toes" syndrome: successful treatment with clonazepam and baclofen.
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The present case is the first report of hypercalcemia induced by vitamin D3 ointment and thiazide simultaneously.
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We report two pediatric cases who developed veno-occlusive disease-like hepatotoxicity while receiving chemotherapy for Wilms' tumor and clear cell sarcoma of kidney.
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The catheter was removed and the abscess was drained.
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A 48-year-old woman with known epilepsy presented to the Emergency Department with a 1-day history of decreasing coordination, impaired speech, and recurrent falls.
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The clinical symptoms of gastric mucosa foveolar hyperplasia due to long-term PGE1 therapy simulate hypertrophic pyloric stenosis.
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We describe two dark-skinned patients who developed hyperpigmented skin and tongue lesions during combination therapy with IFN and ribavirin.
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Although not typical, this result was suspicious of tumor seeding, the more since the lesions appeared in gray matter areas outside the high-dose-rate irradiation field.
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CONCLUSIONS: Clinicians should be aware of the possible association of thrombocytopenia with lansoprazole and discontinue the drug if thrombocytopenia becomes apparent.
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Smoke inhalation injury from newer synthetic building materials--a patient who survived 205 days.
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Patients were followed with sequential ocular examinations for a maximum of 36 weeks.
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Three days after intravitreal injection of bevacizumab, acute ocular ischemic syndrome occurred.
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RSV was the only infectious agent that could be isolated, and treatment with aerosolized ribavirin lead to prompt improvement of all symptoms.
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After cessation of chemotherapy, the pulmonary lesions resolved and all three patients sustained their remissions.
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Alopecia is a rare but important side effect of anti-parkinsonian medications.
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We describe the case of a man with dermatomyositis and stage IV nasopharyngeal cancer treated with chemoradiotherapy and s.c. amifostine.
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Skin rash began after 2 weeks of treatment, and signs of hepatocellular failure developed 3 weeks after phenobarbital had been started.
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To our knowledge, this is the second report of HSOS after standard dose chemotherapy for brain tumor in childhood.
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Fournier's gangrene complicating aggressive therapy for hematologic malignancy.
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Postmortem examination revealed white matter vacuolation in the brain stem tegmentum and cerebellar hemispheres similar to that seen in toxicity from hexachlorophene, to which our patient was not exposed.
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Polymicrobial sepsis is sometimes seen due to enteric organisms adhering to the parasite.
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A treatment, possibly radiation-associated tumor cell alteration resulting in a different catecholamine production, is discussed.
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Clinical manifestations resolved after surgical drainage of the thyroid abscess, prolonged antibiotherapy and diminution of immunosuppressive regimen.
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However, many patients who should receive or be offered preventive treatment are not.
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Adalimumab belongs to the group of tumour necrosis factor-alpha inhibitors and has been approved for the treatment Crohn's Disease since 2007.
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Management of pericatheter cerebrospinal fluid leak after intrathecal implantation of a drug delivery system.
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Common adverse events (frequency 10%) of lacosamide doses up to 600 mg/day include nonspecific central nervous system effects (e.g., dizziness, ataxia, diplopia, and somnolence).
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We present a case of typhlitis in a patient with advanced non-small cell lung cancer (NSCLC) who received pemetrexed, as second-line chemotherapy treatment.
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Although rare, this complication may not be disregarded in the cases that require intraocular corticosteroids for treatment of several conditions, especially in patients who had previously suffered from toxoplasmosis infection.
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TEN is a disease of both children and adults, but TEN in early infancy is a rare event; only two well-documented cases in infants less than 6 months of age have been reported.
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All three cases demonstrate that hyperosmolar hyperglycemic nonketotic coma is a serious potential complication of systemic steroidal therapy, even in a short course of treatment such as is often used in ophthalmology.
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On admission she had 2-3+ pitting edema.
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A 64 year old man with recurrent metastatic squamous cell carcinoma of the head and neck developed severe skin rash and bone marrow aplasia 4 and 7 days, respectively, following a single dose of 40 mg/m2 methotrexate (MTX).
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Thiazide diuretic therapy and chronic photosensitivity.
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The presence of lichen ruber planus and GH insufficiency probably secondary to empty sella are two unusual findings in patients with APECED.
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Sunburn may sometimes be a major injury in psoralen users because high doses or inappropriate use of the drug may render the skin extremely sensitive.
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Glatiramer acetate (copolymer 1, Copaxone) is a mixture of synthetic polypeptides and is used for the treatment of multiple sclerosis.
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Bleomycin pneumonitis potentiated by oxygen administration.
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Eye movement disorders in bone marrow transplant patients on cyclosporin and ganciclovir.
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An evaluation of ovarian structure and function should be considered in women of reproductive age being treated with valproate for epilepsy, especially if they develop menstrual cycle disturbances during treatment.
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This is the first reported use of high-dose-rate remote brachytherapy (HDR) to treat RMS in young children.
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The risk of new-onset diabetic ketoacidosis in patients with diabetic risk factors who are taking perospirone hydrochloride or other atypical antipsychotics should be kept in mind.
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Cerebrovascular complications were the most frequent and were seen in 51% of the liver, 59% of the heart, 58% of the lung, 50% of the heart-lung, 49% of the kidney and 44% of the bone marrow allografts.
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After recovery CT scan follow-up showed marked cerebral atrophy which did not exist prior to the state of coma.
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He was given adriamycin 50 mg/m2 and cyclophosphamide 350 mg/m2 for 6 days followed by 4 days of vincristine 1 mg/m2 and bleomycin 10 mg/m2.
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We review similar reported cases and discuss the direct actions of glucocorticoids on the brain.
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The current report describes a man who was prescribed zonisamide for epilepsy and subsequently developed widespread skin rash, acute kidney injury, high-grade fever, eosinophilia, liver dysfunction, lymphadenopathy and an increase in antihuman herpesvirus-6 immunoglobulin G titer.
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Mutations were detected in the precore region (nt1896) of HBV.
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CASE SUMMARY: A febrile 36-year-old seaman from Mumbai (Bombay) was prescribed >5 times the usual dose of chloroquine for malaria diagnosed empirically onboard ship.
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Even though AZ tends to strongly bind to plasma protein and its clearance is generally poor by hemodialysis (HD), in our patient, HD was observed to be rather effective since the clearance of AZ was 45.8 ml/min on HD and 66 ml/min on direct hemoperfusion (DHP).
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Other causes of acute hepatocellular necrosis were excluded.
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This is a case report of fatal cryptococcal meningitis in a child with systemic lupus erythematosus being treated with prednisolone and azathioprine.
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A retrospective review of TTP patients with quinine-associated thrombotic microangiopathy (TMA) for whom ADAMTS13 was measured before plasma exchange was performed.
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The patients were followed up for an average of 32 months (range 16-75 months).
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This paper presents 3 sisters with Gitelman syndrome who could not tolerate magnesium supplements, and whose hypotension and polyuria were eliminated by taking 2 mg/kg/day indometacin, but who grew poorly.
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Putative drug-related pemphigus foliaceus in four dogs.
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Use of recombinant human hemopoietic colony-stimulating factor was reported to be of benefit in patients who developed agranulocytosis, although there is still some doubt regarding the efficacy in AA.
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Case report.
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She had been treated before with other antipsychotic drugs.
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All-trans retinoic acid (ATRA) has been used successfully in inducing remission in patients with acute promyelocytic leukemia (APL).
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The skin lesions disappeared almost completely within three months.
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This is the first reported case of CNS excitatory toxicities in a patient with alcoholic hepatitis and cirrhosis, and normal renal function.
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The mechanism of the interaction is probably inhibition of glipizide metabolism rather than protein-binding displacement.
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Severe slowly resolving heroin-induced pulmonary edema.
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A 60 year-old woman with chronic renal failure developed acute proximal muscle weakness after receiving a regular dosage of colchicine.
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Brain biopsy in all three disclosed PML and marked perivascular lymphoplasmacytic infiltration.
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Successful treatment of invasive aspergillosis complicating prolonged treatment-related neutropenia in acute myelogenous leukemia with amphotericin B lipid complex.
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METHODS: Switching of agents took place in two ways: converting only antipsychotic medications followed by other psychotropics, and changing all psychotropics simultaneously.
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CONCLUSION: The new quinolone derivatives (levofloxacin, sparfloxacin, grepafloxacin, trovafloxacin, gatifloxacin and moxifloxacin), also called gyrase inhibitors, are known for their potential to cause central nervous system-related adverse effects, including headache, dizziness and insomnia.
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An oral glucose tolerance test showed impaired glucose tolerance with marked insulin resistance.
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An alternative preparation, Mastisol, was successfully used without primarily inducing allergy.
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Pancreatic autoantibody tests were negative before the start of therapy, but a significant increase in glutamic acid decarboxylase (GAD) antibody titer was seen after 24 weeks of treatment.
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The subsequent clinical course was unremarkable until postoperative day 146, when a deep stromal infiltrate was present at the graft-host junction, associated with a dense endothelial plaque.
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Magnetic resonance imaging brain showed features of posterior reversible encephalopathy syndrome, a recognised but rare complication of hypertension in children.
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Risks and benefits should be seriously considered before starting treatment.
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EEG was abnormal and somatosensory-evoked potentials (SEPs) showed giant SEPs, transcortical reflex (C reflex) and jerk locked potentials.
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One patient died of a self-inflicted gunshot wound.
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During these episodes she was lost in herself.
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A clinical case of Cheyletiella infestation on a dog born and raised in Korea is reported.
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A patient with severe cholestatic jaundice induced by captopril is presented.
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Steroids are used extensively in modern medicine and dentistry for their anti-inflammatory and immunosuppressive properties.
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ARDS has been associated with the administration of other monoclonal antibodies, such as infliximab, gemtuzumab ozogamicin, and OKT3 and is believed to be directly mediated by release of proinflammatory cytokines.
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Continuous PGE1 administration ensures patency of the ductus arteriosus, which is essential for stabilizing the general condition until cardiac surgery can be performed.
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However, both patients had abnormally large epidural fat deposits as an underlying and contributing condition.
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Serum sickness consists of a systemic reaction resulting from the formation of soluble circulating immunocomplexes after the introduction of a foreign substance into the body We studied a 38-year-old woman diagnosed with anxiety, depression and right sacroileitis who was treated with phenylbutazone, ranitidine, clomipramine and levomepromazine.
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Six of 13 outpatients with schizophrenia who participated in a ten-week open trial of risperidone had an initial good response to the medication followed by development of intolerable affect, including feelings of agitation and depression and periods of crying and insomnia.
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We describe three HIV-infected patients who were given MTX for severe psoriatic arthritis.
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His muscle symptoms were involved in four limbs and tongue, and deep tendon reflexes were exaggerated.
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In order to investigate the mechanism of late asthmatic response (LAR), inhibitory effects of various drugs for LAR were examined in two wheat flour-sensitive asthmatic subjects who showed immediate and late responses in the allergen provocation test and skin test.
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After reviewing the literature we suggest the CPM was a complication of lithium toxicity which affected the lateral geniculate nucleus which produced blindness.
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We describe a case of pneumonitis following local administration of methotrexate for nonsurgical termination of an ectopic pregnancy.
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During 6 weeks of monitoring, arrhythmia did not recur.
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