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comment
filoleg
2024-10-11T18:12:09
null
The exact same argument can be applied to literally any medical issue, and it is a pointless one.<p>Someone has an elevated risk of skin cancer due to their genetics? Probably an evolutionary trait that it is more likely for some people to get skin cancer within their lifetime. That doesn’t mean that using sunscreen and providing those people with related medical care (if the need arises) is some crime against nature and will end up hurting evolutionary prospects of the human race.
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41,811,723
41,811,263
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[ 41811903 ]
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cyberax
2024-10-11T18:12:16
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&gt; There were several side effects related to pancreatic cancer<p>In mice.
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41,811,263
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[ 41811840, 41811950, 41811838, 41812040 ]
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rthnbgrredf
2024-10-11T18:12:21
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I doubt that you can do it cheaper. To permantenly archive the whole internet is an ongoing task that basically requires a small company, thats why Internet Archive (169 employee) exist (which costs more than 2.5 million dollar per year). It is not done with buying a huge bunch of disk. Setting up a permanent stream to S3 would be the only solution I can think of a single human could handle.
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beretguy
2024-10-11T18:12:26
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Aye, thank you.
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41,809,193
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41,811,804
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LeifCarrotson
2024-10-11T18:12:27
null
Worry is unproductive in the sense of feeling anxiety, sure, but it&#x27;s noble to worry at the various hammers in the archaic definition to &quot;move, proceed, or progress by unceasing or difficult effort, to shake or pull at with the teeth.&quot;<p>Some of the hammers such as the hammer representing nuclear weapons - are caused by people and can be solved by people. There&#x27;s a big game theoretic hill to climb over, but social pressure and advocacy have been effective at making progress. Others, like cancer and general senescence, are more of a looming threat that&#x27;s a fundamental characteristic of biology, we can (and should) worry at them to make incremental progress but we&#x27;re unlikely to suddenly eliminate them. The murder rate is enormously dependent on individual location and individual relationships. Traffic&#x2F;bicycle&#x2F;pedestrian accidents are enormously dependent on individual behavior.<p>Of those threats, addressing the problem of nuclear weapons - especially for a member of Nihon Hidankyo, with a personal and persuasive story of the damages these weapons caused - is probably near the top of the list for actions which can have the greatest positive change.
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41,808,002
41,807,681
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comment
kortilla
2024-10-11T18:12:28
null
Of course it’s an alternative. A self sustaining colony could be the only thing that survives a massive pandemic.
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41,811,462
41,807,681
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[ 41812716 ]
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41,811,806
comment
stackghost
2024-10-11T18:12:29
null
Which CEO is leaning into far-right conspiracy theories and using Twitter to boost the electoral chances of the most dangerous US presidential candidate in history?
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41,810,057
41,805,706
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[ 41811863 ]
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story
jsmithoner
2024-10-11T18:12:33
Show HN: AudioWorkletProcessor Generator Powered by AI
Hello, Here is an editor and generator for audioworkletprocessor class in javascript. The workspace is dedicated to develop this class. You can drag and drop files to test and signup for free credits or use your personal API KEY
https://angular-audio.com/worklet-generator
2
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41,811,807
0
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41,811,808
comment
YouWhy
2024-10-11T18:12:38
null
First of all, 2FA is a jolly good idea in terms of preventing account hijackings; relying on email&#x2F;SMS (texts) introduces multiple hazards that can reverse 2FA&#x27;s net benefit.<p>One configuration some people use is the KeePass desktop password manager, which supports storing TOTP seeds and has a nice UX for generating tokens; the password database file may be located as you see fit on a hard drive, DOK, cloud drive etc. Example of TOTP config for KeePass:<p><a href="https:&#x2F;&#x2F;www.fhtino.it&#x2F;docs&#x2F;keepass-totp--intro&#x2F;" rel="nofollow">https:&#x2F;&#x2F;www.fhtino.it&#x2F;docs&#x2F;keepass-totp--intro&#x2F;</a><p>Also, Keepass2Android can be used in similar vein from Android devices. iOS equivalents seem to exist as well.
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41,806,749
41,806,749
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41,811,809
comment
red-iron-pine
2024-10-11T18:12:39
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because it&#x27;s the same Russian &#x2F; Chinese &#x2F; NK efforts, and all heavily automated.<p>how is this a surprise?
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41,801,454
41,801,271
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41,811,810
comment
ben_w
2024-10-11T18:12:40
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&gt; The reality is probably somewhere in the middle.<p>I think such paradoxes demonstrate we probably need a completely different approach than anything we&#x27;ve done so far.<p>Utilitarianism feels to me like Mill &amp; Bentham discovered basic arithmetic and didn&#x27;t even realise there was more to maths than that.
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41,811,750
41,811,263
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[ 41812376 ]
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41,811,811
comment
bongoman42
2024-10-11T18:12:46
null
This is actually a good breakdown of the two sides. There is an additional thing that the divergence between the people at the top of the two parties and their respective bases is far larger in the case of the left. And the inclusivity of the left has brought together several groups that are highly antithetical to each other and makes for far less predictable and unstable leadership.
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41,804,460
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41,811,812
comment
wantsanagent
2024-10-11T18:12:51
null
Just say &quot;No&quot; to &quot;Free&quot; trials that require a credit card on file.
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41,807,783
41,807,783
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[ 41811931 ]
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41,811,813
comment
mavhc
2024-10-11T18:13:04
null
They should have put a massive trunk in the back to carry goods, and more than 1 seat, and not banned old people from taking trips, those bastards<p>And if you wanted to use inductive charging why didn&#x27;t you acquire a company that does that a few years ago, you can&#x27;t just announce things with no experience in the area, that would be madness
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41,806,174
41,805,706
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41,811,814
comment
lurking_swe
2024-10-11T18:13:12
null
what you say is mostly true, but I will point out that it does not break any spiral. It’s frequently reported that as soon as you stop taking Ozempic, the weight comes back immediately. so unless one resolves the underlying problem, you will be on this drug for life.
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41,811,667
41,811,263
null
[ 41811914, 41813006 ]
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41,811,815
story
coloneltcb
2024-10-11T18:13:14
I Do Not Care About Impediments to a Creepy Growth Hacking Technique
null
https://pxlnv.com/blog/growth-hack/
2
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41,811,815
0
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null
41,811,816
comment
hackinthebochs
2024-10-11T18:13:21
null
Criticality is the boundary between order and chaos, which also happens to be the boundary at which information dynamics and computation can occur. Think of it like this: a highly ordered structure cannot carry much information because there are few degrees of freedom. The other extreme is too many degrees of freedom in a chaotic environment; any correlated state quickly gets destroyed by entropy. The point at which the two dynamics are balanced is where computation can occur. This point has enough dynamics that state can change in a controlled manner, and enough order so that state can reliably persist over time.<p>I would speculate that the connection between grokking and criticality is that grokking represents the point at which a network maximizes the utility of information in service to prediction. This maximum would be when dynamics and rigidity are finely tuned to the constraints of the problem the network is solving, when computation is being leveraged to maximum effect. Presumably this maximum leverage of computation is the point of ideal generalization.
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41,811,264
41,810,753
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[ 41811949 ]
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41,811,817
comment
hosh
2024-10-11T18:13:46
null
There&#x27;s an effort to port uxn to DuskOS (<a href="https:&#x2F;&#x2F;duskos.org&#x2F;" rel="nofollow">https:&#x2F;&#x2F;duskos.org&#x2F;</a>). The goal here isn&#x27;t to be maximally performant or memory efficient (though at this point, running uxn on DuskOS on certain architecture is faster than the mainline uxn implementation).<p>Rather, these are computing platforms to maximize usefulness in the event of a societal collapse.<p>That is why there is a handbook of uxn opscode made to include hand gestures (<a href="https:&#x2F;&#x2F;wiki.xxiivv.com&#x2F;site&#x2F;uxntal_opcodes.html" rel="nofollow">https:&#x2F;&#x2F;wiki.xxiivv.com&#x2F;site&#x2F;uxntal_opcodes.html</a>), so that computing and transmission of computing can continue even with the loss of the computing hardware or documentation.
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41,810,909
41,777,995
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41,811,818
comment
aftbit
2024-10-11T18:13:46
null
Oh yeah, back when Minio was good, before they decided that POSIX filesystems were &quot;legacy technology&quot; and nobody could want to use their product in combination with the cloud, only as an equally-locked-in replacement.<p>Okay I&#x27;m being a bit harsh, but honestly gateway-mode Minio was 1000% better than their current offering.
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41,799,076
41,797,041
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41,811,819
comment
beretguy
2024-10-11T18:13:57
null
Got it. Great! Sorry for my asshole reply.
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41,810,423
41,809,193
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41,811,820
comment
setgree
2024-10-11T18:14:04
null
I would hope this happens, but merely having fewer animals alive in factory farming conditions would be a welfare gain from me because I think a factory farmed animal&#x27;s life falls below the &quot;life is worth living&quot; threshold. YMMV.
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41,811,719
41,811,263
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comment
nescioquid
2024-10-11T18:14:11
null
There is a story about an inventor who approached Trajan[0] with plans for new construction machinery that would require far fewer laborers. Trajan&#x27;s response was incredulous: if he used the new construction equipment, how did he expect he would manage to pay everyone? I.e. the construction project was itself a beneficium to those it employed.<p>[0] Could be another emperor -- I just have an association of this story with Trajan&#x27;s markets for some reason.
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41,811,822
comment
zarathustreal
2024-10-11T18:14:23
null
Right, and the associated cultural impact of increasing hedonism
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41,811,662
41,811,263
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[ 41812669 ]
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story
ontrackglobal
2024-10-11T18:14:26
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1
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41,811,823
null
[ 41811824 ]
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true
41,811,824
comment
ontrackglobal
2024-10-11T18:14:26
null
The blog &quot;21 Best School Management Tools&quot; by OnTrack highlights top software solutions designed to improve school administration. The tools cover areas like student data management, communication platforms, resource scheduling, and school security systems. These technologies help streamline administrative tasks, enhance communication with parents and staff, and ensure real-time access control for better safety and operational efficiency within educational institutions.
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41,811,823
41,811,823
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41,811,825
comment
ssl-3
2024-10-11T18:14:28
null
Can it not be cryptographically proven?<p>Leave a public key in your HN bio.<p>And leave a matching private key and validation instructions in your will.<p>If the keys match along with a death certificate, then: The account owner is validated as being dead.
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41,809,879
null
[ 41812117, 41812651 ]
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41,811,826
story
mitya777
2024-10-11T18:14:30
Infinitely Branching Chat
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https://home.treechat.ai/quest/df7df6da-402d-40f0-8735-b3ce9e49f7aa
1
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41,811,826
0
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41,811,827
comment
chermi
2024-10-11T18:14:31
null
What? Physics programs don&#x27;t work like that, at least not T1-2 ones I know about. A physics PhD is not pay to play and anyone thinking it is would fail out on their qual at every university I&#x27;m familiar with.
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41,803,568
41,786,101
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[ 41812572 ]
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41,811,828
comment
SV_BubbleTime
2024-10-11T18:14:32
null
I don’t think that’s a great comparison.<p>Have you wondered why ADHD has exploded?<p>Have you not realized how many people at hacker news are on SSRIs? Watch this comment, you will.
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41,811,790
41,811,263
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comment
jancsika
2024-10-11T18:14:39
null
&gt; So if my self-image is, &quot;I&#x27;ve advanced our understanding of the fundamental nature of reality,&quot; then the idea that my contributions weren&#x27;t useful becomes painful.<p>Only if one believes the logical fallacy that the dependent steps of a process of elimination weren&#x27;t useful.
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41,808,404
41,808,127
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[ 41812113 ]
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comment
w0m
2024-10-11T18:14:44
null
it&#x27;s easier to ignore 100 papercuts than it is to ignore missing a hand.
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41,808,396
41,807,681
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[ 41812373 ]
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41,811,831
comment
kortilla
2024-10-11T18:14:48
null
Boil it
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41,809,132
41,807,681
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41,811,832
comment
DrillShopper
2024-10-11T18:14:56
null
I don&#x27;t think I&#x27;ve ever seen someone seriously put forth the argument &quot;all you need is Ozempic&quot;.<p>For context: I am an overweight type 2 diabetic. I lost about 70 lbs before my doctor started me on Mounjaro (another GLP-1 agonist). My diet and exercise routine were far from perfect, and it took me about a <i>year</i> to lose that weight. My doctor started me on Mounjaro, both for type 2 diabetes and weight loss. I have lost 20 lbs in about a month on it, which means I will lose <i>three times</i> the weight if that pace keeps up (very unlikely). When my doctor and I discussed starting Mounjaro (which the doctor suggested, not me) he made it very, VERY clear that diet and exercise were important things to work on as the weight came off.<p>The key there is that the pace of weight loss will not keep up as the body&#x27;s caloric needs reduce due to that weight loss. So naturally a GLP-1 user will plateau if they do not adjust their diet (and potentially exercise routine, though diet is much more important) as the weight comes off. You know what really makes it easier to have the energy to a healthy meal, to work out, and to take care of yourself? Losing weight! You know what helps form those healthy habits in people who did not form them during childhood? Reduced cravings for calorie dense food! Both of those things are where Ozempic and other GLP-1 drugs shine. It gives the person on them the space to make those changes without cravings, without feeling hungry, and at a faster pace than they could do naturally.<p>So yes, in the short term, these drugs are a great catalyst for change, but I don&#x27;t see many medical professionals saying &quot;oh just stick someone on Ozempic for life and that&#x27;s that!&quot; because for the vast majority of people who would use those drugs for weight loss cannot achieve their goals with just the drug alone.
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41,811,617
41,811,263
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41,811,833
comment
jrflowers
2024-10-11T18:14:57
null
Wait is the “Wikileaks” here the Reddit post or is the “Wikileaks” the couple of links to public news sites?
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41,810,971
41,805,706
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comment
cyberax
2024-10-11T18:14:57
null
It&#x27;s not the manic behavior, but the opposite. GLP-1 agonists appear to reduce the impulsive behavior.
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41,811,789
41,811,263
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[ 41811940, 41812010 ]
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41,811,835
comment
jijji
2024-10-11T18:15:03
null
you can buy tirzepatide &#x2F; semaglutide all day long from labs in china for between $4 per injection all the way down to $0.50 per injection depending on quantity and type (prepackaged in vial vs raw powder)
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41,811,263
41,811,263
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[ 41812341 ]
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41,811,836
story
nateb2022
2024-10-11T18:15:15
Pepsi's Soviet Navy (2021)
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https://foreignpolicy.com/2021/11/27/pepsi-navy-soviet-ussr/
2
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41,811,836
0
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41,811,837
comment
cynicalpeace
2024-10-11T18:15:25
null
In terms of 20-50 years where will we be if the Ukraine conflict continues? At best an entrenched, decades long conflict, where we&#x27;re at odds with 2 major nuclear powers. At worst, we&#x27;re all dead. Including my children.<p>Over a bunch of neoliberal theories proposed by the architects of the last number of catastrophic wars? No thanks.<p>The left&#x2F;Democrats&#x2F;progressives used to be anti-war. But they&#x27;ve been entirely co-opted as a result of Trump derangement syndrome.
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41,808,822
41,807,681
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[ 41812185 ]
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41,811,838
comment
copperx
2024-10-11T18:15:27
null
Did the drug help pancreatic cancer?
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41,811,801
41,811,263
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41,811,839
story
kunarmando
2024-10-11T18:15:28
Ask HN: How does GTM for pre-revenue early stage startup look like?
Hey! While designing a pitch deck for an accelerator, one question always pops up in my head about what should we write about GTM being pre-revenue early stage startup? I get the target audience, testing right hypothesis, distribution channels, but I feel YC content doesn&#x27;t provide the clear answer to this situation. Other content dictates a version of GTM that&#x27;s way beyond our stage, series A at least.<p>I&#x27;m wondering, does that mean we are too early to apply for an accelerator?<p>Thanks to all taking a look.
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1
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41,811,839
1
[ 41811865 ]
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41,811,840
comment
minifridge
2024-10-11T18:15:28
null
If something causes cancer in mice, the curent consensus is that it is deemed unsafe for humans.
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41,811,801
41,811,263
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[ 41811927 ]
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41,811,841
comment
red-iron-pine
2024-10-11T18:15:35
null
votes are part of it; she&#x27;s also drawing attention away from other topics the GOP would prefer to not get looked at...<p>...like how all of the GOP voted against federal aid for the hurricane victims, esp. several in southern states that got hit.
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41,801,271
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41,811,842
comment
matthoiland
2024-10-11T18:15:49
null
&gt; If you own dead&#x2F;brown&#x2F;unoccupied land, you&#x27;re an asshole.<p>Well said.<p>But yes, we should all be re-reading Progress and Poverty (1879), as our world shares many similarities.
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41,789,228
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41,811,843
comment
xethos
2024-10-11T18:15:53
null
Fords history of working with the cops and saying &quot;Here&#x27;s what we have, what fits best as a base to modify, how can <i>we</i> meet <i>your</i> needs?&quot; that is older than Tesla&#x27;s founding<p>The F-150 Lightning may not be dramatically better, but an OEM willing to work with you can make all the differnece in the world
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41,811,139
41,810,627
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story
brodo
2024-10-11T18:15:58
Realtalk binders by Bret Victor (2022)
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https://dynamicland.org/archive/2022/Realtalk_binders
1
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41,811,844
0
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41,811,845
comment
FireBeyond
2024-10-11T18:16:10
null
&gt; and needed a quick recovery. We seem to be at stuff like that every thousand or so miles, down from every mile five years ago. it is WAY WAY WAY ahead of any other car I&#x27;ve driven or ridden in that can be bought.<p>That&#x27;s orders of magnitudes better than other FSD users.<p>Independent testing of over 1,000 miles through Southern California required 77 interventions, at an average of once every 13 miles.<p>I suspect your &quot;one intervention every one thousand miles&quot; might be a little optimistic.
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41,807,412
41,805,706
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[ 41812735 ]
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41,811,846
comment
talldayo
2024-10-11T18:16:17
null
Who would have guessed: profiting off video streaming is prevented by making adblock accessible. News at 11.<p>I&#x27;m entirely sympathetic to the idea that Google abuses their advertising business, but people demanding Google get taken to court for making Chrome-only sites are going to be sorely disappointed. The internet is a free market that will converge on the most attractive featureset even if it&#x27;s not healthy for users. That means that all businesses that rely on advertising like Google does for YouTube will inevitably end up with a similar strategy. Twitch.tv certainly isn&#x27;t controlled by Google, but they&#x27;ll happily degrade an adblocker&#x27;s experience until it&#x27;s unusable because ads are their moneymaker.<p>If you don&#x27;t want to use Firefox, try WebKit. You&#x27;ll gain an appreciation for &quot;not as good&quot; as opposed to &quot;barely functional&quot;, trust me.
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41,809,888
41,801,202
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41,811,847
comment
dtkav
2024-10-11T18:16:23
null
Obsidian is free for individual use. The $50&#x2F;yr is a commercial license. They also have a $4&#x2F;month sync product (sync across devices with e2e encryption), but you can use icloud, google drive, etc too.
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41,808,943
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41,811,848
comment
indiebat
2024-10-11T18:16:33
null
&gt; Break out from the spiral<p>I see the point in this, but do you think it’s marketed as such and perhaps better question, used for exactly that and not more by vulnerable patients etc? (not well informed about long term side effects, some might even be unknown, if I might add)<p>I take my vaccines and generally gravitate to sanity over conspiracy stuff (that is to say, If I sound like that, i’m not)
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41,811,667
41,811,263
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41,811,849
comment
mavhc
2024-10-11T18:16:33
null
Doesn&#x27;t distributed computing generally cope with nodes going offline?<p>The point is it&#x27;s just a way to use free compute that&#x27;s sitting around, if you want to sign up to use it you&#x27;d obviously make sure it was in wifi range
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41,807,631
41,805,706
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41,811,850
comment
optimalsolver
2024-10-11T18:16:36
null
What happened to self-control?
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41,811,263
41,811,263
null
[ 41811990, 41811999, 41812009 ]
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41,811,851
comment
s1artibartfast
2024-10-11T18:16:37
null
&gt;Yeah, the problem isn&#x27;t masculinity nor a mixed gender work environment. It&#x27;s mindsets like this.<p>The stronger interpretation of this point is not about mixed gender work environments, but heavily skewed ones.<p>Just as women may feel uncomfortable and face challenges in a heavily skewed workplace, men (also being human) have the same experience when the roles are reversed.<p>I dont think I would want to work somewhere that was 4:1 women.
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41,811,050
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[ 41812904 ]
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story
Zobat
2024-10-11T18:16:47
Lego the Movie went physically viral on a plane
null
https://www.thepoke.com/2024/02/08/this-fabulous-tale-of-an-in-flight-movie-that-went-old-school-viral-is-making-everyones-day-better/
2
null
41,811,852
0
null
null
null
41,811,853
comment
lurking_swe
2024-10-11T18:16:47
null
I think the answer to your question is that people who avoid drugs understand that drugs do not fix anything permanently, in 99% of cases. They only treat symptoms. The people who avoid drugs attempt to treat the underlying problems.<p>of course it’s not always practical. For example, some skinny people are simply genetically predisposed to high blood pressure, even if they work out and eat pretty healthy. It’s rare, but these things happen.
null
null
41,811,734
41,811,263
null
null
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41,811,854
comment
cynicalpeace
2024-10-11T18:16:51
null
When did Russia withdraw from the nuclear testing treaty?
null
null
41,809,226
41,807,681
null
[ 41812280 ]
null
null
41,811,855
comment
K0balt
2024-10-11T18:16:58
null
lol. Interesting stuff but here I was thinking this was about the new transformer architecture.<p>Differential Transformer <a href="https:&#x2F;&#x2F;arxiv.org&#x2F;abs&#x2F;2410.05258" rel="nofollow">https:&#x2F;&#x2F;arxiv.org&#x2F;abs&#x2F;2410.05258</a>
null
null
41,784,521
41,784,521
null
[ 41811888 ]
null
null
41,811,856
comment
jackcosgrove
2024-10-11T18:17:07
null
To address the question in your first paragraph, I think it&#x27;s due to whether you think your locus of control is internal or external.
null
null
41,811,734
41,811,263
null
[ 41812019 ]
null
null
41,811,857
comment
dtkav
2024-10-11T18:17:24
null
They must be talking about the commercial license.<p>[0] <a href="https:&#x2F;&#x2F;obsidian.md&#x2F;pricing" rel="nofollow">https:&#x2F;&#x2F;obsidian.md&#x2F;pricing</a>
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null
41,811,351
41,808,943
null
null
null
null
41,811,858
comment
brudgers
2024-10-11T18:17:35
null
4500kg is ~10,000lbs. That&#x27;s about where the US draws the line, <a href="https:&#x2F;&#x2F;ai.fmcsa.dot.gov&#x2F;NewEntrant&#x2F;MC&#x2F;Content.aspx?nav=License" rel="nofollow">https:&#x2F;&#x2F;ai.fmcsa.dot.gov&#x2F;NewEntrant&#x2F;MC&#x2F;Content.aspx?nav=Lice...</a><p>There are of course exceptions.
null
null
41,810,051
41,794,912
null
null
null
null
41,811,859
comment
danieldk
2024-10-11T18:17:46
null
One thing to keep in mind is that if your provider uses PPPoE, it is quite CPU-heavy. Moreover the netgraph-based PPPoE implementation that pfsense&#x2F;opnsense uses is single-threaded. So if you have a multi-gig connection, you need a CPU with very good single-thread performance. Linux has a multi-threaded implementation, so it&#x27;s probably less of an issue on OpenWrt.<p>Interestingly, some ARM SoCs that are worse on paper do much better because they hardware-accelerate PPPoE (e.g. recent MediaTek Filogic SoCs or some Qualcomm&#x2F;Marvel SoCs). Most of those routers also use less power and have great WiFi. The downside (coming back to buffer bloat) is that they may not be able to do multi-gbit SQM.
null
null
41,797,423
41,793,658
null
null
null
null
41,811,860
comment
mritchie712
2024-10-11T18:17:55
null
Has there ever been a case where something like #2 has happened?<p>Don&#x27;t think you need to worry about that one.
null
null
41,811,539
41,811,263
null
[ 41812114, 41811875, 41813012, 41812154, 41812277 ]
null
null
41,811,861
comment
dang
2024-10-11T18:18:00
null
Related: <i>Dismantling the Ship That Drilled for the Ocean&#x27;s Deepest Secrets</i><p><a href="https:&#x2F;&#x2F;www.nytimes.com&#x2F;2024&#x2F;08&#x2F;26&#x2F;science&#x2F;drilling-ship-science-joides-resolution.html" rel="nofollow">https:&#x2F;&#x2F;www.nytimes.com&#x2F;2024&#x2F;08&#x2F;26&#x2F;science&#x2F;drilling-ship-sci...</a><p><a href="https:&#x2F;&#x2F;archive.is&#x2F;3UMcU" rel="nofollow">https:&#x2F;&#x2F;archive.is&#x2F;3UMcU</a><p>(via <a href="https:&#x2F;&#x2F;news.ycombinator.com&#x2F;item?id=41360598">https:&#x2F;&#x2F;news.ycombinator.com&#x2F;item?id=41360598</a>, but no comments there)
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null
41,785,543
41,785,543
null
null
null
null
41,811,862
comment
copperx
2024-10-11T18:18:01
null
It would be interesting to compare the anxiolytic effects of the drug versus the cancer anxiety caused by being on the drug.<p>The cancer anxiety could be reduced by frequent testing. e.g., having a thyroid ultrasound every 6 months, or a yearly abdominal MRI, just to make sure cancer is not brewing.
null
null
41,811,603
41,811,263
null
[ 41811930, 41812030 ]
null
null
41,811,863
comment
mavhc
2024-10-11T18:18:02
null
The Twitter that&#x27;s barely used by anyone and thus isn&#x27;t important?<p>Surely they should be using facebook, that&#x27;s already proven to be great at helping with genocides
null
null
41,811,806
41,805,706
null
[ 41812398 ]
null
null
41,811,864
comment
beretguy
2024-10-11T18:18:13
null
I’ll wait for other people to test it.
null
null
41,811,341
41,811,341
null
[ 41812059 ]
null
null
41,811,865
comment
rogerkirkness
2024-10-11T18:18:17
null
Customer development is when founders cold email (or Tweet, whatever is appropriate) and talk to customers trying to test the following in the following orders:<p>1. Is the problem that you&#x27;re going to solve important? Do people respond to cold email about a hypothesis to solve it? (testing problem relevance)<p>2. Is the solution that you put forward realistic sounding to customers? Do they believe that you&#x27;ll be able to build it, and want it if you do? (testing solution relevance)<p>3. When you show customers an early version of what you&#x27;re building, do they ask to use it (testing problem&#x2F;product fit)<p>4. When early users get access to your sketchy prototype, do they usage retain? Regardless of funds changing hands, do they keep using it?<p>If you have a product where you can email people about a problem, who consistently reply, see a demo of your product and ask to use it, then adopt it and continue using it without pressure, you should figure out pricing.
null
null
41,811,839
41,811,839
null
null
null
null
41,811,866
comment
brudgers
2024-10-11T18:18:24
null
The article is paywalled for me.
null
null
41,794,698
41,794,697
null
null
null
null
41,811,867
comment
FireBeyond
2024-10-11T18:18:32
null
&gt; Why isn’t any other car company doing it?<p>No other car company offers it, or promises it&#x27;s coming next year, or ...<p>Similarly, who actually believes a $39,000 CyberTruck will EVER appear?<p>Crickets?
null
null
41,809,984
41,805,706
null
null
null
null
41,811,868
comment
dghlsakjg
2024-10-11T18:18:34
null
Anecdotally, I disagree.<p>I went through a period of vegetarianism (for health reasons, not directly for ethics), and once I started eating meat again, 1. I eat a lot less, which 2. means that I can be much more intentional about sourcing it.<p>Right now the bulk of the meat that I eat at home throughout the year comes from 1 or 2 animals that are locally sourced and butchered (normally I share a portion of a pig and a cow), and the occasional wild caught fish. The meat is tastier, and I can go see the actual animals at the farm if I so choose. They are not factory farmed, and the price per pound is about the same as buying industrial meat at the grocery store since I am buying directly from the farmer, and paying a local processor for their services.<p>As things wane in popularity it might be true that they become more of a commodity, or it might be true that they become more of a niche product where people care more.<p>I would like to think that if meat consumption becomes more of a treat than an everyday thing, that people would treat it as such, and go out of their way to eat something that tastes better.<p>Food for thought?
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null
41,811,739
41,811,263
null
null
null
null
41,811,869
comment
talldayo
2024-10-11T18:18:35
null
&gt; GPUs (CUDA) are orthogonal to consumer processors (ARM &#x2F; X86).<p>We&#x27;re talking about vector operations. CUDA is not a GPU but a library of hardware-accelerated functions, not necessarily different from OpenCL or even NEON for ARM. You can reimplement everything CUDA does on a CPU, and if you&#x27;re using a modern CPU you can vectorize it too. x86 handles this well, because it&#x27;s still got dedicated logic that keeps pace with the SIMD throughput an integrated GPU might offer. ARM leaves out the operations entirely (which is smart for efficiency), and therefore either relies on someone porting CUDA code to an ARM GPU shader (fat chance) or offloading to a remote GPU. It&#x27;s why ARM is excellent for sustained simple ops but collapses when you benchmark it bruteforcing AI or translating AVX to NEON. SIMD is too much for a base-spec ARM core.<p>&gt; Maybe we could assume a platonic ideal merged chip, a CPU that acts like a GPU, but there&#x27;s more differences between those two things than an instruction set for vector ops.<p>Xeon Phi or Itanium flavored?
null
null
41,810,799
41,808,013
null
[ 41812263 ]
null
null
41,811,870
comment
GeoAtreides
2024-10-11T18:18:39
null
but op wasn&#x27;t talking about what extensions are seeing, but what the ad servers do. You haven&#x27;t address their point at all
null
null
41,811,022
41,809,698
null
null
null
null
41,811,871
comment
yohannparis
2024-10-11T18:18:57
null
Could you provide some of those papers? I&#x27;m interested on what you are saying, but I am not able to find what you are mentioning using the link you provided.
null
null
41,811,762
41,811,263
null
[ 41811923 ]
null
null
41,811,872
comment
bshanks
2024-10-11T18:19:04
null
One of the authors talks about using C with SDL or libdraw here: <a href="https:&#x2F;&#x2F;news.ycombinator.com&#x2F;item?id=31715080">https:&#x2F;&#x2F;news.ycombinator.com&#x2F;item?id=31715080</a><p>Since they were on a boat with a Raspberry Pi and not much battery power or internet, in addition to execution speed and portability, they were probably also concerned with:<p>- speed of compilation and linking (on small machines like Raspberry Pi)<p>- binary size of anything that might have to be updated or shared over the internet<p>- having to troubleshooting emergent issues without the ability to lookup documentation or download updates or tools from the internet<p>In this situation, a simpler language on a simpler VM is probably going to be faster to develop with than compiling&#x2F;linking a subset of C, and after the initial implementation of the VM, might present less opportunity for an unintended interaction of leaky abstractions in your libuxn and your toolchain to ruin your day on a day when you don&#x27;t have internet connectivity to check Stackoverflow or to update some buggy dependency.
null
null
41,810,909
41,777,995
null
null
null
null
41,811,873
comment
red-iron-pine
2024-10-11T18:19:13
null
do you expect there to be 100 pages in English about obscure Chinese gossip and conspiracy?
null
null
41,805,044
41,801,271
null
[ 41811934 ]
null
null
41,811,874
comment
giantg2
2024-10-11T18:19:14
null
Only when applied correctly and with other interventions. Using ozempic without diet and exercise changes is like putting a bandaid on a .5&quot; deep wound without sterilizing it.
null
null
41,811,695
41,811,263
null
[ 41812630, 41812433 ]
null
null
41,811,875
comment
dustingetz
2024-10-11T18:19:23
null
<a href="https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Water_fluoridation" rel="nofollow">https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Water_fluoridation</a>
null
null
41,811,860
41,811,263
null
[ 41812062, 41811920 ]
null
null
41,811,876
comment
filoleg
2024-10-11T18:19:24
null
Why either&#x2F;or?<p>Maybe we should try educate society on dangers of using heroin. I agree that it is a good thing, and we should continue educating people about its dangers. But clearly that alone didn’t solve the problem, and I think it would be a good idea to utilize alternative options as well (in addition to continuing the education of society on its dangers).
null
null
41,811,623
41,811,263
null
null
null
null
41,811,877
story
bhushannemade
2024-10-11T18:19:29
null
null
null
1
null
41,811,877
null
null
null
true
41,811,878
comment
btilly
2024-10-11T18:19:29
null
I&#x27;m not the one you&#x27;re replying to, but the claim seems very reasonable to me.<p>Fundamental breakthroughs in how to think about scientific subjects usually are created by fairly small groups of people. A lot more people are involved in popularizing it, and then filling out the details. But it is rare for it to start with a large number of people.<p>For example that list in the case of quantum mechanics was Max Planck, Albert Einstein, Niels Bohr, Louis de Broglie, Max Born, Paul Dirac, Werner Heisenberg, Wolfgang Pauli, and Erwin Schrödinger.<p>You can think of this as the scientific version of the 2 pizza rule.
null
null
41,811,591
41,808,127
null
[ 41812127, 41812368 ]
null
null
41,811,879
comment
hipadev23
2024-10-11T18:19:55
null
Who has time to eat? Founder mode all day every day.
null
null
41,811,263
41,811,263
null
null
null
null
41,811,880
comment
cyberax
2024-10-11T18:19:56
null
&gt; basically toxic diet<p>This is a bullshit term. Even fast food is not &quot;toxic&quot;, it&#x27;s just calorie-dense.<p>I got overweight eating nothing but &quot;healthy&quot; diet because I have never _liked_ fast food.
null
null
41,811,558
41,811,263
null
null
null
null
41,811,881
comment
DrillShopper
2024-10-11T18:19:57
null
&gt; I still work on eating healthy, but now I&#x27;m not just HUNGRY at all moments.<p>I think this is something a lot of people pushing back against the GLP-1 agonists don&#x27;t realize because they don&#x27;t experience it: back before I started Mounjaro (another GLP-1 agonist) I was <i>constantly</i> hungry if I hadn&#x27;t eaten a meal in the last 45 minutes. Absolutely zero hyperbole there - I once went to an all you can eat buffet, ate until I was over full, came home, and within about an hour and a half of that I was snacking on something because I was hungry. Not peckish. Not &quot;feeling like a snack&quot;. Hungry to the point where that feeling intruded on my every thought until it was sated.<p>After starting Mounjaro that&#x27;s <i>GONE</i>. Gone gone. I now have to set an alarm to <i>remember</i> to eat. It&#x27;s absolutely phenomenal and likely the reason why I&#x27;ll live past my forties instead of being stuck in that same cycle and dying of the effects of obesity.
null
null
41,811,754
41,811,263
null
[ 41812119, 41812309 ]
null
null
41,811,882
story
swyx
2024-10-11T18:20:00
AI Neocloud Playbook and Anatomy
null
https://www.semianalysis.com/p/ai-neocloud-playbook-and-anatomy
1
null
41,811,882
0
null
null
null
41,811,883
comment
randomdata
2024-10-11T18:20:01
null
Maybe. There is some evidence that the decline in fertility rates are associated with overweight and obesity. Social and biological factors leave having children more difficult when one is outside of a &quot;normal&quot; weight range. If everyone is on Ozempic, they might have more children, requiring more overall food and harming even more animals in the process.
null
null
41,811,732
41,811,263
null
[ 41812123 ]
null
null
41,811,884
story
bhushannemade
2024-10-11T18:20:03
null
null
null
1
null
41,811,884
null
null
null
true
41,811,885
comment
cynicalpeace
2024-10-11T18:20:04
null
He explicitly said he&#x27;ll try to get peace before he even gets sworn into office.<p>I don&#x27;t think he&#x27;ll succeed that quick, but that&#x27;s <i>way</i> better than pushing for further conflict.<p>And again, under his administration we saw more peace than any president since at least Clinton.
null
null
41,808,889
41,807,681
null
null
null
null
41,811,886
comment
giantg2
2024-10-11T18:20:13
null
And using ozempic without those diet changes is the same damn thing. You need to work on it from both directions.
null
null
41,811,720
41,811,263
null
null
null
null
41,811,887
comment
giantg2
2024-10-11T18:20:35
null
Way to strawman. That&#x27;s not what I said.
null
null
41,811,774
41,811,263
null
[ 41812625, 41812452 ]
null
null
41,811,888
comment
topspin
2024-10-11T18:20:36
null
Likewise. I was pleased to find this instead.
null
null
41,811,855
41,784,521
null
null
null
null
41,811,889
comment
fuddle
2024-10-11T18:20:38
null
Nice work, it would be great to see some benchmarks comparing it to llm.c.
null
null
41,811,078
41,811,078
null
null
null
null
41,811,890
comment
stephenr
2024-10-11T18:20:43
null
Thanks for posting this. I&#x27;m going to link back to this whenever anyone claims that using AWS&#x2F;etc means you don&#x27;t need any experienced infrastructure&#x2F;ops people.<p>As for the actual question: what browser&#x2F;password manager in 2024 doesn&#x27;t support both options 1 and 2?
null
null
41,806,749
41,806,749
null
[ 41812142 ]
null
null
41,811,891
comment
mock-possum
2024-10-11T18:20:44
null
Do you have the time to seek out and keep healthy food? Can you afford it? Do you have the executive function and impulse control etc to bring to bear the necessary self discipline?<p>You’re making some pretty casual assumptions about people’s abilities.
null
null
41,811,669
41,811,263
null
null
null
null
41,811,892
story
mfiguiere
2024-10-11T18:20:45
Arm Exploring io_uring for Graphics Drivers
null
https://www.phoronix.com/news/DRM-Graphics-Drivers-IO_uring
4
null
41,811,892
0
null
null
null
41,811,893
comment
swyx
2024-10-11T18:20:49
null
have you ever read a good expanation of why Minsky Moments happen? it always occured to me if you can time them right you can make a ton of money on the way up and on the way down
null
null
41,808,718
41,805,446
null
null
null
null
41,811,894
comment
6510
2024-10-11T18:20:50
null
If it needs to be fast use oldskool for() loops.<p><pre><code> function processfor(input){ let sum = 0 for (let i = 0; i &lt; input.length; i++){ if (input[i] % 2 !== 0){ continue } sum += input[i] * 2 } return sum } </code></pre> <a href="https:&#x2F;&#x2F;jsfiddle.net&#x2F;gaby_de_wilde&#x2F;y7a39r15&#x2F;5&#x2F;" rel="nofollow">https:&#x2F;&#x2F;jsfiddle.net&#x2F;gaby_de_wilde&#x2F;y7a39r15&#x2F;5&#x2F;</a>
null
null
41,801,337
41,769,275
null
null
null
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41,811,895
story
Bostonian
2024-10-11T18:20:53
null
null
null
2
null
41,811,895
null
null
null
true
41,811,896
comment
eniwnenahg
2024-10-11T18:20:55
null
In EU they banned the sale of oral tobacco (snus), which is safer than smoking tobacco. Snus once had cancer labeling but that was generally considered not-very-true and labeling was removed. Tobacco smoke causes cancer. Drug bans also built many overfilled prisons and likely contributed to the invention and spread of harmful drugs such as crystal meth and fentanyl. This is a one sided view of course. I like William Blakes work, &quot;Auguries of Innocence&quot;.
null
null
41,811,715
41,811,263
null
null
null
null
41,811,897
comment
rahimnathwani
2024-10-11T18:21:00
null
Yeah I get that. I don&#x27;t think my son is ready for something effortful like LingQ. So, even if Duolingo is only a tenth as effective per unit of time spent, it&#x27;s better than nothing.
null
null
41,811,798
41,807,783
null
null
null
null
41,811,898
comment
brianbrown
2024-10-11T18:21:04
null
1. Most tea consumed worldwide is of Asian origin. Camellia sinensis is native to East Asia.<p>&quot;On any given day, more than one half of the American population drinks tea. On a regional basis, the South and Northeast have the greatest concentration of tea drinkers.&quot;<p>Source: <a href="https:&#x2F;&#x2F;www.teausa.com&#x2F;teausa&#x2F;images&#x2F;Tea_Fact_2021.pdf" rel="nofollow">https:&#x2F;&#x2F;www.teausa.com&#x2F;teausa&#x2F;images&#x2F;Tea_Fact_2021.pdf</a><p>Tea may easily contain 5 to 10 times as much fluoride as fluoridated water.<p>2. TOTAL intake is what determines fluoride toxicity. This has been established since the 1930s when fluoride was discovered to be the source of &quot;mottled enamel&quot; - dental fluorosis.<p>In 1991, total intake among adults in fluoridated areas in the US was estimated to be up to 6.6 mg&#x2F;day. (US PHS, 1991)<p>&quot;The daily intake of most adults is about equally divided among food, drinking water, beverages, and mouthrinses.&quot; (U.S. Dept. Health &amp; Human Services, Report on fluoride benefits and risks. MMWR Recomm Rep. 1991 Jun 14;40(RR-7):1-8. PMID: 2051975.)
null
null
41,765,140
41,757,346
null
null
null
null
41,811,899
comment
grecy
2024-10-11T18:21:04
null
My god no.<p>I&#x27;m 42 and I&#x27;ve never taken more than the odd painkiller or antibiotic here or there - less than a pill a year on average I&#x27;m sure.<p>The last thing in the world I want is to be permanently on some drug that alters how my body works. I hike, snowboard, go to the gym and eat sensibly. That&#x27;s all the &quot;weight control&quot; I need.
null
null
41,811,263
41,811,263
null
[ 41811974, 41811996 ]
null
null