def METHOD_NAME(sequence: Sequence[U32]) -> Uint:
    """
    Obtain Uint from a U32 sequence assuming that this sequence is little
    endian i.e., the first U32 number of the sequence is the least
    significant U32 number.
    Parameters
    ----------
    sequence :
        The U32 stream (little endian) which is to be converted to a Uint.
    Returns
    -------
    value : `Uint`
        The Uint number obtained from the conversion of the little endian
        U32 stream.
    """
    sequence_as_bytes = le_uint32_sequence_to_bytes(sequence)
    return Uint.from_le_bytes(sequence_as_bytes)