def METHOD_NAME(sender, instance, **kwargs):
    dependents = instance.document.form.questions.exclude(
        calc_dependents=[]
    ).values_list("calc_dependents", flat=True)
    dependent_questions = list(itertools.chain(*dependents))
    for question in models.Question.objects.filter(pk__in=dependent_questions):
        _update_or_create_calc_answer(question, instance.document)