def METHOD_NAME(value, system):
    if 'examined_loci' in value:
        for locus in value['examined_loci']:
            if 'expression_measurement_method' in locus:
                if locus['expression_measurement_method'] == 'CRISPRi-FlowFISH':
                    locus['expression_measurement_method'] = 'PrimeFlow'
            else:
                gene = locus['gene']
                locus['expression_measurement_method'] = 'qPCR'
                if 'notes' in value:
                    value['notes'] = f'{value.get("notes")} Upgraded expression_measurement_method to qPCR for examined_loci gene {gene}.'
                else:
                    value['notes'] = f'Upgraded expression_measurement_method to qPCR for examined_loci gene {gene}.'