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| "instruction": "Answer this question truthfully", | |
| "input": "Can you provide an overview of the lung's squamous cell carcinoma?", | |
| "output": "Squamous cell carcinoma of the lung may be classified according to the WHO histological classification system into 4 main types: papillary, clear cell, small cell, and basaloid." | |
| }, | |
| { | |
| "instruction": "Answer this question truthfully", | |
| "input": "What does \"Clear: cell\" mean?", | |
| "output": "Clear cell tumors are part of the surface epithelial-stromal tumor group of Ovarian cancers, accounting for 6% of these neoplastic cases. Clear cell tumors are also associated with the pancreas and salivary glands.\nBenign and borderline variants of this neoplasm are rare, and most cases are malignant.\nTypically, they are cystic neoplasms with polypoid masses that protrude into the cyst.\nOn microscopic pathological examination, they are composed of cells with clear cytoplasm (that contains glycogen) and hob nail cells (from which the glycogen has been secreted).\nThe pattern may be glandular, papillary or solid." | |
| }, | |
| { | |
| "instruction": "Answer this question truthfully", | |
| "input": "Can you provide me with information regarding statins?", | |
| "output": "Two Japanese scientists commenced research into inhibitors of HMG-CoA reductase in 1971 reasoning that organisms might produce such products as the enzyme is important in some essential cell wall components. This work lead to the identification of the first clinically useful compound lovastatin(mevinolin) from a mould in the mid 1970's. This agent was first used in the more severe forms of hypercholesteraemia in the 1980s followed by landmark trials with simvastatin that showed the potential for cardio-prevention. Cerivastatin was withdrawn in 2001 because of a ten times higher incidence of rhabdomyolysis than the other statins." | |
| }, | |
| { | |
| "instruction": "Answer this question truthfully", | |
| "input": "What are the historical background and symptoms of Candida-induced vulvovaginitis?", | |
| "output": "Symptoms of vulvovaginitis caused by Candida species are indistinguishable and include the following: \nPruritus is the most significant symptom Change in the amount and the color of vaginal discharge: It is characterized by a thick, white \"cottage cheese-like\" vaginal discharge Pain on urination (dysuria) Pain on sexual intercourse (dyspareunia) Vulvovaginal soreness Symptoms aggravate a week before the menses" | |
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| { | |
| "instruction": "Answer this question truthfully", | |
| "input": "What does the \"Hypotension: Resident Survival Guide\" refer to?", | |
| "output": "Hypotension is the term for low blood pressure (BP). A systolic BP measuring less than 90mmHg and/ or diastolic BP of less than 60mmHg is considered hypotension. A difference of 20 mmHg systolic BP and 10 mmHg diastolic BP is considered orthostatic hypotension (OH). Orthostatic hypotension is the most common type of hypotension, and neurogenic hypotension is demonstrated among 1/3rd of the individuals with OH. A decrease in blood pressure can be life-threatening in conditions such as anaphylaxis and addisonian crisis, and requires prompt treatment. It is important to access the possibility of head injury in a patient with syncope due to hypotension. ECG is an important and essential component of the evaluation of hypotension. Shock requires prompt management with fluids and vasopressors. For other causes of hypotension, identifying the cause and treatment is the best strategy. Lifestyle modifications are usually the first step in management. Medications causing a drop in blood pressure should be discontinued or changed to an appropriate alternative." | |
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