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What is Which of the following is best for diagnosing genital TB? and explain in detail?
Ans. (c) LJ mediumRef: Harrison 19th ed. /1110* Harrison states: "In genitourinary TB - culture of 3 morning urinary specimen yields a definitive diagnosis in 90% cases. LJ medium is most common solid medium used for culture.* Prevalence of GU TB= 10-15%* MC c/o- Urinary frequency, dysuria, nocturia, hematuria, and flank or abdominal pain.* Diagnosis- Culture of three morning urine specimens- definitive diagnosis in nearly 90% patient.* Other test- IV pyelography, abdominal CT, MRI-may show deformities and obstructions* Suggestive findings- calcifications and ureteral strictures-* Complication-# Female- affects the fallopian tubes and the endometrium and may cause infertility, pelvic pain, and menstrual abnormalities.# Diagnosis requires biopsy or culture of specimens obtained by dilation and curettage.# Male- affects the epididymis, producing a slightly tender mass that may drain externally through a fistulous tract; orchitis and prostatitis may also develop.* Rx: Genitourinary TB responds well to chemotherapy.