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What is False about Pseudomyoxma peritonei is and explain in detail?
Ans. (b) Refractory to drugsRef: Sabiston 20th ed; pg. 1080 & Bailey 27th ed; pg. 1316Explanation:* Pseudomyxoma peritonei is a rare condition which describes mucinous ascites arising from a ruptured ovarian or appendiceal carcinoma.* First described by Fraenkel, condition typically has progressive peritoneal tumor deposits, mucinous ascites, omental cake and ovarian involvement in females* Most commonly associated with appendiceal tumor* Occurs most commonly in patients who are 40 to 50 years of age and occurs in equal frequency in both males and females* Risk of developing pseudomyxoma peritonei following removal of appendix harbouring epithelial tumor is 9%, non mucinous neoplasm is 3% and 30% with mucinous adenocarcinoma* Current accepted treatment is Cytoreductive surgery with Heated or Hyperthemia Intra Peritoneal Chemotherapy (CRS + HIPEC) which includes omentectomy, stripping of involved peritoneum, resection of involved organs and appendicectomy.The survival rates after CRS + HIPEC increased from 20 to 30% to 55% nowadays