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What is E6, E7 genes of which virus are implicated in oncogenesis - and explain in detail?
Ans. is 'd' i.e., HPV o HPV selectively infects the epithelium of skin and mucous membrane and may immortalize the keratinocytes leading either asymptomatic infection, or warts or neoplasia. o Products of E-genes (E6, E7) are related to immortalization or malignant transformation of keratinocytes by interfering with p53 and Rb genes, respectively.