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What is Inotropic drugs acts on which receptors:March 2013 and explain in detail?
Ans. C i.e. Beta1Beta adrenergic receptorsActivation of beta-1 receptors induces positive inotropic, chronotropic output of the cardiac muscle, leading to increased hea rate and blood pressure, secretion of ghrelin from the stomach, and renin release from the kidneys.Activation of beta-2 receptors induces smooth muscle relaxation in the lungs, gastrointestinal tract, uterus, and various blood vessels. Increased hea rate and hea muscle contraction is also associated with the beta-2 receptors.Beta-3 receptors are mainly located in adipose tissue. Activation of the beta-3 receptors induces the metabolism of lipids.