You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Child with proteinuria, generalised edema. With hypoproteinemia & hyperlipidemia-M.C. cause is? and explain in detail?
Ans. is 'a' i.e., Minimal change N.S. Nephrotic syndrome characterised by :? Massive proteinuria = (more than 1 gm/m2/day). Hypoalbuminemia (serum albumin below 2.5 g//dl). Edema Hyperlipidemia often associated. Resultant fall in plasma oncotic pressure leads in edema. Stimulation of Renin - Angiotensin system causes sodium & water retention. More than 90% of childhood N.S. is primary. Most common cause of primary N.S. is minimal change. In electron microscopy, Histopathology show loss of podocyl and loss of negatively charged protein leads to selective proteinuria (albumineria