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What is ratelimiting enzyme in fatty acid synthesis ? and explain in detail?
Fatty Acid Synthesis * Fatty acids are built from 2-C units derived from acetyl-CoA * Acetate units are activated for transfer to growing FA chain by conversion to malonyl-CoA * Decarboxylation of malonyl-CoA and reducing power of NADPH drive chain growth * Chain grows to 16-carbons (eight acetyl-CoAs) * Other enzymes add double bonds and more ref : lipincott 9th ed