You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which of the following Hepatitis has worst prognosis and explain in detail?
Answer is D (HDV super-infection on HBV): HDV superinfection of a person with chronic Hepatitis B (HBV) has the worst prognosis with high likelihood of fulminant hepatitis and death. Among patients ill enough to be hospitalized for acute hepatitis B infection the case finality rate is 1%. Patients with simultaneous acute hepatitis B and hepatitis D do not necessarily experience a higher moality rate than do patients with acute hepatis B alone, however in several recent outbreaks of acute simultaneous HBV and HDV infection amongst injection drug users the case fatality rate has been - 5%. In the case of HDV super infection of a person with chronic hepatitis B, the likelihood offuhninant hepatitis and death is increased substantially. In out breaks of severe HDV super infection in isolated populations with a high hepatitis B carrier state the moality has been recorded in excess of 20% - Harrison's 1e/2552 Prognosis in HBV Infection Acute HBV infection simultaneous HBV- HDV confection << HDV super-infection on HBV infection (Best prognosis) (worst prognosis)