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What is Aspirin is used for ischemic heart disease: and explain in detail?
Ans. A. Inhibit TXA2 synthesisAspirin is irreversible COX inhibitor. At low dose 40-325mg they act as antiplatelet agent. They inhibit TXA2 synthesis which is platelet aggregator but also inhibit PGI2 which is platelet anti aggrator. But the net effect is TXA2 inhibition.