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What is All are true about familial male limited precocious pubey, EXCEPT: and explain in detail?
Familial male limited precocious pubey is also called testotoxicosis. FACTS : It is an autosomal dominant disorder It presents as premature androgenization of boys Testosterone is elevated, LH is suppressed in the condition Treatment options : 1. Ketoconazole - Inhibits testosterone synthesis. 2. Flutamide - Used as an androgen receptor antagonist. 3. Anastrazole - Is a useful aromatase inhibitor. Ref: Harrison, Edition - 18, Page - 3015