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What is HIV mostly affects which cells? and explain in detail?
harshmohan textbook of pathology 7th edition. *the pathogenesis of HIV infection is largely related to the depletion of CD4 + T cells resulting in preformed immunosuppression .Selective tropism for CD4+ molecule receptors, gp 120 envelope glycoprotein of HIV has selective tropism for the cells containing CD 4 molecules on their surface,most impoantly CD4+T cells