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What is In Testicular Feminization syndrome Gonadectomy is indicated : and explain in detail?
At pubey Patients of Testicular Feminization syndrome (Androgen insensitivity) are genotypically males (Karyotype 46XY) but phenotypically females (i.e. male pseudo hermaphroditism). Due to the presence of Y chromosome gonads are testis which remain intraabdominal and have a malignant potential (Most common = Gonadoblastoma, Dysgerminoma). Therefore testis should be removed in such patients. B/L Laparoscopic Gonadectomy is the preferred proceduredeg. As far as timing of Gonadectomy is concerned ? "In patient with complete androgen insensitivity, the testis should be removed 'ter Pubeal developmen is complete to prevent malignant degeneration.