You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Loss of social inhibition occurs when the site of disease is? and explain in detail?
Ans. D. Frontal cortexFrontal Lobe LesionA. Foster Kennedy syndromeB. Features: Ipsilateral optic atrophy and contralateral papilledemaC. A tumor of the frontal lobe is likely to damage the pre-frontal network. This presents as two relatively distinct syndromes.a. Frontal disinhibition syndromei. Socially disinhibited and shows severe impairment of judgment, insight and foresight.ii. Antisocial behavior is a characteristic feature of frontal disinhibition syndrome produced from frontal lobe damageb. Frontal abulic syndromei. Loss of initiative, creativity and curiosityii. Pervasive emotional apathy and blandnessiii. Akinetic mutismD. Urinary incontinence can occur in lesion of paracentral lobule area of frontal lobe.E. Frontal release signs - Grasp reflex, palmomental response, rooting reflex.