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What is Chrugstrauss involves following except ? and explain in detail?
Ans. is `d' i.e., Hea Churg-Strauss syndrome It is an autoimmune small-vessel vasculitis associated with peripheral eosinophilia, cutaneous purpura, mononeuritis, asthma, and allergic rhinitis. Hypergammaglobulinemia, elevated levels of serum IgE, or the presence of rheumatoid factor sometimes accompanies the allergic state. Lung inflammation, including fleeting cough and pulmonary infiltrates, often precedes the systemic manifestations of disease by years. A third of patients may have exudative pleural effusions associated with eosinophils. Small-vessel vasculitis and focal segmental necrotizing glomerulonephriti scan be seen on renal biopsy, usually absent eosinophils or granulomas. Interestingly, some asthma patients treated with leukotriene receptor antagonists will develop this vasculitis.