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What is Fluoroquinolone with highest oral bioavailability and explain in detail?
Fluoroquinolones:- * Gemifloxacin is a third generation fluoroquinolone having absolute oral bioavailability. * All third generation fluoroquinolones: Sparfloxacin, Gatifloxacin and Gemifloxacin have 100% oral biovailability. * Among the Fluoroquinolones, Norfloxacin has the least oral bioavailability. Ref:- HL & KK Sharma's Principles of Pharmacology 3rd Ed; Pg Num:- 724