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What is "Diluting segment" of a nephron is: and explain in detail?
Thick ascending LOH is k/a the diluting segments of the nephron. It is impermeable to water. It has NKCC cotranspoer proteins that reabsorb Na+, K+, 2Cl- ions. Thus,There is a net reabsorption of solutes with no movement of water, making the tubular fluid that reaches the DCT hypotonic.