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What is Which of the following is the most common cause of clinically significant consumptive coagulopathy? and explain in detail?
One of the most common causes of clinically significant consumptive coagulopathy in obstetrics is placental abruption. Major mechanism of consumption coagulopathy are Disseminated intravascular coagulation (DIC) and to a lesser degree retroplacental bleeding. It is associated with hypofibrinogenemia (less than 150mg/dl), raised D dimer and fibrin degradation products, and low level of coagulation factors factor V, VIII.