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What is Agglutination test in CSF sample is done for - and explain in detail?
Ans. is 'c' i.e., Cryptococcus Laboratory diagnosis of crvptococcal infectiono Lumbar puncture is the single most useful diagnositc testo Following tests are usedA) Serology# The most useful serological test is LPA test (Latex agglutination test for the detection of cryptococcal polysaccharide capsular antigen).# This is highly specific and sensitive; and gives better results than direct microscopy and cultures.B) Direct microscopy# Unstained wet preperations of CSF mixed with drop of India ink or nigrosine demonstrate the capsule as a clear halo.# Methenamine silver or periodic acid-Schiff are used for staining a tissue sample.C) Culture# Can be easily cultured from CSF on sabouroud's agar.