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What is Drug ezetimibe act by? and explain in detail?
Ezetimibe acts by inhibiting the intestinal absorption of cholesterol and phytosterols. It interferes with a specific CH transpo protein NPC1C1 in the intestinal mucosa and reduces the absorption of both dietary and biliary CH. (REF. ESSENTIALS OF MEDICAL PHARMACOLOGY K.D TRIPATHI-6th edition.Page No-618)