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What is Principal serum enzyme used in clinical diagnosis of Wilson disease and explain in detail?
Serum enzymeDiseaseAspaate aminotransferase(AST, or SGOT)Myocardial infarctionAlanine aminotransferase(ALT, or SGPT)Viral hepatitisAmylaseAcute pancreatitisCeruloplasminHepatolenticular degeneration(Wilson disease)Creatine kinaseMuscle disorders and myocardialinfarctiong-Glutamyl transferaseVarious liver diseasesLactate dehydrogenaseisozyme 5Liver diseasesLipaseAcute pancreatitisb-GlucoscerebrosidaseGaucher diseasePhosphatase, alkaline(isozymes)Various bone disorders,obstructive liver diseasesRef: Harper&;s Biochemistry; 30th edition; Chapter 7 Enzymes: Mechanism of Action