You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A 30 years man presented with nausea, fever and jaundice of 5 days duration. The biochemical tests revealed a bilirubin of 6.7 mg/dl (conjugated 5.0 mg/d1) with SGOT/SGPT (AST/ALT) of 1230/900 IU/ml. The serological tests showed presence of HBs Ag IgM anti-HBc and HBeAg. The most likely diagnosis: and explain in detail?
Ans. (b) Acute hepatitis B infection with high infectivity See the following table, Do not try to learn it, just try to understand Commonly Encountered Serologic Patterns of Hepatitis B Infection HBsAg Anti-HBc Anti-Hac HBeAg Anti-HBe Interpretation + - lgM + - Acute hepatitis B, high infectivity + - lgG + - Chronic active Hepatitis B, high infectivity + - lgG - + 1. Late acute or chronic hepatitis B, low infectivity 2. HBeAg-negative (precore mutant) hepatitis B + + + +/- +/- 1. HBsAg of one subtype and heterotypic anti-HBs (common) 2. Process of seroconversion from HBsAg to anti-HBs (rare) - - lgM +/- +/- Acute hepatitis B Anti-HBc "window" - - lgG - +/- Low-lenel hepatitis B carrier or hepatitis B in remote post - + lgG - +/- Recovery from hepatitis B - + - - - 1. lmmunization with HBsAg (after vaccination)2. Hepatitis B in the remote past3. False-positive