You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Jejunal biopsy is diagnostic in: and explain in detail?
Per-oral jejunal biopsy is used in the diagnosis of malabsorption syndromes: Celiac sprue Amyloidosis Whipple's disease Lymphoma Abetalipoproteinemia Scleroderma. Malabsorption Syndrome Jejunal biopsy findings Non-tropical sprue Blunting or absence of the villi, Substitution of cuboidal for columnar surface cells, Infiltration of the lamina propria with lymphocytes and plasma cells. Amyloidosis Deposition of amyloid in the lamina propria and around blood vessels. Whipple's disease Villi of the intestinal mucosa are thickened and have bulbous tips, Laminae propria contain foamy histiocytes and lipid deposits Lymphoma Mucosal lesions may be identical to those seen in spure Lamina propria -lymphocytic cellular infiltrations Abeta-lipoproteinemia Numerous vacuoles of fat are found in the epithelial cells. Scleroderma Collagen deposition around Brunner s glands