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What is Effacement of foot process of nephron is seen in? and explain in detail?
* Minimal change renal disease is the most common form of idiopathic nephrotic syndrome in children of age group 2 to 6 years. It accounts for around 85% of cases and are mostly steroid sensitive.* The finding in renal biopsy in light microscope is usually normal. Electron microscope shows effacement of epithelial foot process.* Other most commonly asked question in nephrotic syndrome is the indication for renal biopsy -# Age group less than 1 and more than 10 years# Steroid resistant nephrotic syndrome# Steroid dependent nephrotic syndrome# Nephritic onset nephrotic syndrome# Persistent hematuria and hypo complement levels more than 2 months# Before starting cyclosporine analog drugs.