You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A six year old child is admitted to the Paediatric ICU for seizures. He has been on tretment with Tacrolimus and Prednisolone. On investigations his blood urea is 68 mg/d1, Serum Sodium is 136 meq/1 likely cause of his seizures- and explain in detail?
Ans. is 'd' i.e., Tacrolimus Toxity Tacrolimus neurotoxicity is an established cause for 'seizures' and the most likely reason for seizures in this child. In hyponatremia, seizures usually develop when sodium levels decrease below 125 meq/L. In hypocalcemia, seizures develop when calcium level is below 6 mg/dl. Uremic seizures occur late after delirium, hallucinations and agitation.