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What is Rosiglitazone mechanism of action is - and explain in detail?
Ans. is "a' i.e., Acts as PPAR gamma agonist [Ref KDT 7*/ep. 276\Rosiglitazoneo It is oral antidiabetic drugo They are selective agonists for nuclear peroxisome proliferator activator receptor gamma (PPAR gamma) expressed in the fat and muscle cells.o It enhances transcription of several insulin responsive genes,o Reverse insulin resistance by enhancing GLUT 4 expression and translocation.