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What is Alcohol in substrate inducer for which gene? and explain in detail?
Ans. is 'a' i.e., Pol III gene Alcohol induces pol III gene (RNA polymerase III-dependent genes) transcription in vivo and in vitro. Brfl specifically regulates pol III gene transcription. Changes in pol III gene and Brfl expression tightly link to cell transformation and tumor formation. Alcohol induced deregulation of pol III genes may be fundamental to the development of breast cancer.