You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which of the following is not TRUE about bone metastasis? and explain in detail?
"Skeletal metastases are typically multifocal, not unifocal" Metastases are usually osteosclerotic and pathologic fractures are common. Osteoblastic lesions are rare and typically seen in carcinoma prostate. Osteoblastic lesion are associated with higher level of alkaline phosphatase and if extensive my produce hypoglycemia. "The commonest source of bony metastases, is carcinoma of the breast; next in frequency are carcinoma of prostate (in males), kidney, lung, thyroid bladder and gastrointestinal tract Ref: Apley's Ohopedics 8/e, Page 193; Robbins 7/e, Page 1303.