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What is Disseminated intravascular coagulation (DIC) is characterized by the following except and explain in detail?
DIC is characterised by bleeding & organ damage due to ischemia caused by the effect of widespread intravascular thrombosis. Platelet count is reduced due to platelet aggregation & adhesion as a result of endothelial injury. Prothrombin time & activated paial thromboplastin time are prolonged due to reduced fibrinogen. Fibrinogen is reduced due to consumption in microvascular coagulation. Fibrin degradation products are raised due to secondary fibrinolysis.Reference :Harsh mohan textbook of pathology sixth edition pg no 338.