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What is Ba's hydrops fetalis is lethal because - and explain in detail?
Ans. is 'c' i.e., Hb Ba's cannot release oxygen to fetal tissues `In the foetus excess gamma globin chains form tetramers (Hb Bas) with such high affinity for oxygen that they deliver almost no oxygen to tissues' - Robbins o Clinically this condition manifests as hydrops fetalis and fetus shows features similar to those of erythroblastosis fetalis ----> Severe pallor, Generalized edema, Massive hepatosplenomegaly