You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Primary immune response is mediated by? and explain in detail?
The primary immune response is the antibody response to an initial antigen. It is mediated by IgM. With most antigens, IgG is a late antibody and makes it appear after initial immune response which is IgM in nature. Reference : Anathanarayan & paniker's 9th edition, pg no:97, 146 <\p>