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What is Gluten sensitive enteropathy is strongly associated with: and explain in detail?
Gluten enteropathy/Celiac Sprue It is associated with HLA -DQ2 Due to auto Ab against brush border epithelium which is present in the gut mucosa Clinical Feature-Osmotic diarrhoea Auto ab: Anti tissue transglutaminase Ab - Screening test Small intestinal mucosal Biopsy - Confirmatory test Treatment: No 'BROW'(Barley, Rye, Oats, Wheat) Only maize is allowed