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What is Which of these is not a non-contraceptive use of levonorgestrel? and explain in detail?
Ans: B. Premenstrual tension(Ref Williams 24/e p701: Goodman Gilman 12/e p1184, 1190)Pre-menstrual tension is not a non-contraceptive use of levonorgestrel.Therapeutic Uses - Levonorgestrel:Emergency contraception:Useful within 120 hours as emergency bih control.Idiopathic menorrhagia:Excessively heavy, regular menses in the absence of intracavitary pathology or coagulopathy.Menometrorrhagia:Excessive bleeding in amount prolonged in duration (regular or irregular intervals).An alternative delivery system - Protect against endometrial hyperplasia in women taking SERM.Management of recurrent pelvic pain secondary to multi- treated endometriosis.LNG-IUS is licensed for use in menorrhagia & to provide endometrial protection to perimenopausal & postmenopausal women on estrogen replacement therapy.LNG-IUS beneficial in endometriosis, adenomyosis, fibroids, endometrial hyperplasia & early stage endometrial cancere (where the patient is deemed unfit for primary surgical therapy).