You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is The following drug is used recently in Alcohol dependence patients and explain in detail?
(B) Naltrexone # Rehabilitation of Alcoholics> While the mainstay of alcoholic rehabilitation involves counseling, education, and cognitive approaches, several medications might be useful.> The first is the opioid-antagonist drug Naltrexone, 50 to 150 mg/d, which has been reported in several small-scale, short-term studies to decrease the probability of a return to drinking and to shorten periods of relapse.> However, at least one longer-term large-scale trial questioned the superiority of naltrexone to placebo, and more studies are required before the cost-effectiveness of this approach can be established.> A second medication, acamprosate (Campral), 2 g/d, has been tested in >5000 patients in Europe, with results that appear similar to those reported for naltrexone.> Several long-term trials of naltrexone and acamprosate, used individually and in combination, are in progress, and early results are promising.> A third medication, which has historically been used in the treatment of alcoholism, is the ALDH inhibitor disulfiram.> In doses of 250 mg/d this drug produces an unpleasant (and potentially dangerous) reaction in the presence of alcohol, a phenomenon related to rapidly rising blood levels of the first metabolite of alcohol, acetaldehyde.