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What is A new born presented with bloated abdomen sholy after bih with passing of less meconium. A full thickness biopsy rectal biopsy finding is most likely to be present. and explain in detail?
.hirschsprung disease is a congenital, familial condition, occurring in newborn due to the absence of ganglion cells-- Auerbach's and Meissner's plexus in anorectum, which may extend proximally either a pa or full length of the colon. * It always involves the anus, internal sphincter and rectum (paly or entirely). * There is narrow, spasmodic, non relaxing pathological segment. * Transitional zone proximal to it contains only few ganglion cells with formation of cone. ref:SRB&;s manual of surgery,ed 3,pg no 818