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What is . Primary biliary cirrhosis is positive for and explain in detail?
Primary Biliary Cirrhosis(PBC) - A progressive autoimmune liver disease characterised by non suppurative, inflammatory destruction of intra hepatic bile ducts. Characteristic autoantibody detected in primary biliary cirrhosis is antimitochondrial antibody Consequences: bile duct destruction-impaired secretion of bile, cholestasis, and inflammatory reaction in the poal tract-hepatic damage, fibrosis- cirrhosis and liver failure. SYSTEMIC AND GENERAL PATHOLOGY RAMDAS NAYAK PG NO 461 IMAGE REF: