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What is Tumor that follows rule of 10 is - and explain in detail?
Ans. is 'a' i.e., Pheochromocytoma Note-o Pheochromocytomas usually subscribe to a convenient "rule of 10s":-10% of pheochromocytomas arise in association with one of several familial syndromes. These include the MEN-2A& MEN-2B syndromes, type I neurofibromatosis, von Hippel-Lindau syndrome & Stuige-Weber syndrome.10% of pheochromocytomas are extra-adrenal, occurring in sites such as organ of Zuckerkandl & carotid body, where these chromaffin-negative tumors are usually called paragangliomas to distinguish them from pheochromocytomas.10% of nonfamilial adrenal pheochromocytomas are bilateral: this figure may rise to 70% in cases that are associated with familial syndromes.10% ofadrenal pheochromocytomas are biologically malignant, although the associated hypertension represents a serious & potentially lethal complication of even "benign1" tumors.10% of adrenal pheochromocytomas arise in childhood, usually the familial subtypes, and with a strong male preponderance. The nonfamilial pheochromocytomas most often occur in adults between 40 & 60 years of age, with a slight female preponderance.