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What is Most common post operative complication in polycythemia vera- and explain in detail?
Increased risk of urate stones and gout due to hyperuricemia is seen in polycythemia vera. Relative Reduced plasma volume (hemoconcentration) Absolute Primary Abnormal proliferation of myeloid stem cells, normal or low erythropoietin levels (polycythemia vera); inherited activating mutations in the erythropoietin receptor (rare) 2.secondary Increased erythropoietin levels Adaptive: lung disease, high-altitude living, cyanotic hea disease Paraneoplastic: erythropoietin-secreting tumors (e.g., renal cell carcinoma, hepatomacellular carcinoma, cerebellar hemangioblastoma) Surreptitious: endurance athletes Reference :textbook of Pathology ,author Harsha Mohan 7th edition page number 339 RefRobbins 9/e pg 425