You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Flow cytometry is done to know - and explain in detail?
Ans. is 'a' i.e., Rapid cell shrinkage o As there is no inflammation in apoptosis - there is no leukocyte migration.Apoptotic cells or apoptotic bodies (end products) are phagocytosed by macrophages,o Endonuclease causes double stranded breaks of nuclear DNA. The nucleus itself may break up producing two or more fragments.o Activation of caspases is central to the pathogenesis of apoptosis. :-Following are the method to identify the apoptopic cellsStaining of chromatin condension by haematoxylin, Feulgen and acridine orange.Flow cytometry to visualise rapid cell shrinkage.DNA changes in situ technique or by electrophoresis,Annexin V as a marker of apoptotic cell.