You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Craniosynostosis occurs due to premature fusion of and explain in detail?
Craniosynostosis is the premature fusion of one or more cranial sutures, either major (e.g. metopic, coronal, sagittal and lambdoid) or minor (frontonasal, temporosquamosal, and frontosphenoidal). Cranial sutures normally fuse during early childhood, staing with the metopic suture (beginning at 2 months), followed by sagittal, coronal and lambdoid sutures (22-26 months), such that the frontonasal and frontozygomatic sutures close last (68-72 months). Premature fusion restricts the growth of the skull perpendicular to the affected suture. Compensatory skull growth occurs parallel to the affected suture in order to accommodate the growing brain. The resulting skull deformity is termed as scaphocephaly, plagiocephaly or trigonocephaly based on the suture involved. Cloverleaf skull deformity is caused by the fusion of multiple sutures and is associated with hydrocephalus. Patients with tower skull or acrocephaly have combined sagittal, coronal and lambdoid synostosis, often as pa of Ape or Crouzon syndrome. Oxycephaly or turricephaly refers to a tall cranium resulting from delayed repair of brachycephaly and is often syndromic.