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What is At the end of repolarization, the nerve is hyperpolarized. How does the membrane potential return to RMP? and explain in detail?
Simultaneously with the action of the pump, there is inward diffusion of Na+ through the leaky channels (not the voltage-gated channels that cause depolarization). This inward leakage of positive charges will take the membrane potential from - 90 mV to original RMP of - 70 mV. Both the pump and the inward leakage will balance out once the potential again reaches - 70 mV.