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What is Nilutamide is an: and explain in detail?
Antiandrogen -Flutamide and bicalutamide, nilutamide antagonise androgen action on prostate carcinoma and have a palliative effect in advanced/metastatic cases. Because they increase androgen levels, combination with orchiectomy or GnRH analogs is required to produce a full therapeutic effect. (REF. Essentials of Pharmacology TD TRIPATHI 6th EDITION page no 828)