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What is Cholesterosis is - and explain in detail?
• It is an acquired histologic abnormality of the gallbladder epithelium that results in an excessive accumulation of lipid (cholesterols esters and triglyceride)Q within epithelial macrophage of the GB wall.
• Cholesterol stones are found in half of the cases.
Pathology
• Gross Appearance: The mucosa has pale, yellow streaks running longitudinally giving rise to the term strawberry gallbladder (although the mucosa is usually bile stained rather than red).
• Diffuse form (“strawberry gallbladder”): GB mucosa is brick red and speckled with bright yellow flecks of lipid.
• Localized form: Solitary or multiple “cholesterol polyps” studding the gallbladder wall.
Treatment
• Cholecystectomy is indicated in symptomatic cholesterolosis or when cholelithiasis is present.