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What is Duodenal ulcer is most commonly caused by:March 2013 (c, d, e) and explain in detail?
Ans. D i.e. H. pyloriPeptic ulcer/Peptic ulcer diseaseIt is defined as mucosal erosions equal to or greater than 0.5 cm.As many as 70-90% of such ulcers are associated with Helicobacter pylori, a helical-shaped bacterium that lives in the acidic environment of the stomach.Four times as many peptic ulcers arise in the duodenum--the first pa of the small intestine, just after the stomach--as in the stomach itself.About 4% of gastric ulcers are caused by a malignant tumor, so multiple biopsies are needed to exclude cancer.Duodenal ulcers are generally benign.