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What is Risk of rubella to fetus is maximum, if the mother is infected in: and explain in detail?
Risk of rubella to fetus is maximum, if the mother is infected in 6-12 weeks. Timing of fetal infection determines the extent of teratogenic effect in fetus Ist 2 months Abnormalities in 65-85% cases, Multiple congenital defects (cataracts, deafness and hea defects) Spontaneous aboion 3rd month of fetal life: 30% to 35% chance of developing a single defect, Deafness ,CHD. During the 4th month 10% risk for a single congenital defect Beyond the 4th month No risk to fetus