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What is Most abundant type of collagen in human body and explain in detail?
The major structural protein found in connective tissue is the collagen..It is the most abundant protein found in body. Type I is the most abundant forn , seen in connective tissues in almost all regions of the body. Type II is mainly seen in cailage and vitreous humor. Type III is seen in skin, lung and vascular tissues and Typa IV is seen in the basement membranes. THE COLLAGEN IS SYNTHESIZED BY FIBROBLASTS INTRACELLULARLY,AS A LARGE PRECURSOR,CALLED PROCOLLAGEN.iT IS THEN SECRETED. REFERENCE: DM VASUDEVAN TEXTBOOK SEVENTH EDITION ; PAGE NO :720