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What is Vascular involvement and thrombosis is seen in - and explain in detail?
The agents of zygomycosis (Rhizopus,Mucor) are angioinvasive. In humans, they invade tissues of patients with reduced host defense. From there, they enter the blood vessels and proliferate in the walls of blood vessels paicularly paranasal sinuses, lungs, or intestines. This results in infarction and necrosis of tissues distal to blocked vessels. Aspergillus can cause paranasal sinuse and lung cavity infection but not angioinvasive. Coccidiodomycosis- m/c pulmonary infection, other skin lesions and joint pain. Histoplasmosis- cause primary pulmonary infection with cavitation