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What is The probable interval between throat infection and onset of rheumatic fever is and explain in detail?
Rheumatic fever is an acute, immunologically mediated, multisystem inflammatory disease that occurs after group A b-hemolytic streptococcal infections (usually pharyngitis, but also rarely with infections at other sites such as skin). Acute rheumatic fever occurs most often in children; the principal clinical manifestation is carditis. Neveheless, about 20% of first attacks occur in adults, with ahritis being the predominant feature. Symptoms in all age groups typically begin 2 to 3 weeks after streptococcal infection, and are heralded by fever and migratory polyahritis. (Robbins basic pathology,9th edition.pg no.391)