You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is True statement regarding Bupivacaine is: and explain in detail?
Bupivacaine is more cardio toxic than Lignocaine as it more prone to prolong QTc interval and induce ventricular tachycardia or cardiac depression- should not be used for intravenous regional anesthesia. It has high lipid solubility: distributes more in tissues than in blood after spinal or epidural injection . Therefore less likely to reach foetus. Hence used widely in obstetrics . From Tripati 7th edition Page no 367