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What is A one year old child presents with sho stature, lethargy, & constipation. Clinical examination shows a palpable goiter. Laboratory investigations revealed a low T4 and elevated TSH which of the following is the most likely diagnosis. and explain in detail?
Child with presence of a palpable goitre ,along with clinical and laboratory features of hypothyroidism suggests a diagnosis of thyroid dyshormonogenesis from the options listed in the question. Ref: Pediatrics By Lloyd J. Brown, Lee Todd Miller page 168.