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What is Level of prolactin above which hyperprolactinemia term is used is? and explain in detail?
Normal adult serum PRL levels are about 10-25 mg/L in women and 10-20 mg/L in men. PRL secretion is pulsatile, with the highest secretory peaks occurring during rapid eye movement sleep. Peak serum PRL levels (up to 30 mg/L) occur between 4:00 and 6:00 a.m. The circulating half-life of PRL is about 50 min. Hyperprolactinemia refers to prolactin levels more than 200mg/L in blood and most common cause is PRL-secreting pituitary adenomas called as prolactinoma. Hyperprolactinemia is the most common pituitary hormone hyper-secretion syndrome in both men and women.