You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Urinary anion gap is an indication of excretion of which of the following? and explain in detail?
Urinary anion gap is calculated using the equation, urinary anion gap = ( Na+ + K+) - (Cl-). It reflects the ability of the kidney to excrete NH4Cl. During metabolic acidosis, kidneys normally eliminate NH4+Cl- to enhance the removal of excess H+ion. In response to acidosis, daily urinary excretion of NH4Cl can be increased from 30 mEq to 200 mEq. Ref: Harrison's Principle of Internal Medicine, 16th Edition, Page 368 ; Current Medical Diagnosis and Treatment 2012, Chapter 21