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What is Which receptors are present in liver for uptake of LDL: and explain in detail?
Apo E and Apo B100 "Apolipoproteins carry out several roles: (1) they can form pa of the structure of the lipoprotein, eg, apo B; (2) they are enzyme cofactors, eg, C-II for lipoprotein lipase, A-I for lecithin:cholesterol acyltransferase, or enzyme inhibitors, eg, apo A-II and apo C-III for lipoprotein lipase, apo C-I for cholesteryl ester transfer protein; and (3) they act as ligands for interaction with lipoprotein receptors in tissues, eg, apo B-100 and apo E for the LDL receptor, apo E for the LDL receptor-related protein (LRP), which has been identified as the remnant receptor, and apo A-I for the HDL receptor. The functions of apo A-IV and apo D, however, are not yet clearly defined."-Harper 26/ p206 "The liver and many extrahepatic tissues express the LDL (B-100, E) receptor. It is so designated because it is specific for apo B-I00 but not B-48..." - Harper 26/e p209