You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is In diabetic nephropathy all of the following are true, except- and explain in detail?
Diabetic nephropathy (diabetic kidney disease) is kidney damage that results from having diabetes. Having high blood glucose levels due to diabetes can damage the pa of the kidneys that filters your blood. The damaged filter becomes 'leaky' and lets protein into your urine . Insulin therapy in type 1 diabetic patients with ove diabetic nephropathy is characterized by two features: while suffering from a considerably increased risk of severe hypoglycemic episodes , they show poorer metabolic control than diabetic patients with normal renal function . The increased hypoglycemic risk may be paially explained by the decline in renal insulin clearance, as 30-80% of systemically circulating insulin is removed by the kidneys . A reduction of insulin clearance has been described in nondiabetic patients with end-stage renal failure and mild to moderate renal impairment ; however, until now, it has not been studied in patients with diabetic nephropathy. Ref - diabetes journals.com