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What is Spoligotyping is done for ? and explain in detail?
Ans. is 'c' i.e., Mycobacterium tuberculosis Spoligotyping (spacer oligotyping) is a type of polymerase chain reaction (PCR). Compared with other PCR-based methods that combine detection and typing of such DNA, spoligotyping is more sensitive, because it targets the direct repeats (DRs) present in multiple (sometimes up to 60) copies in the genomic DR locus of M. tuberculosis complex bacteria.The well-conserved 36-bp DRs are interspersed with nonrepetitive spacer sequences of 34 to 41 bp in length (2, 3, 4).