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What is Zileuton is - and explain in detail?
Ans. is 'a' i.e., 5 lipooxygenase inhibitor 5-lipoxygenase inhibitoro 5-lipoxygenase involved in production of leukotrienes especially LTB4 (chemoattractant) and LTC4, LTD4 (Bronchoconstrictor). These are the most important mediators in bronchial asthma.o Zileuton inhibits 5-lip>>xygenase and thereby the production of leukotrienes. Therefore, Zileuton is useful in the treatment of asthma.