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What is Limulus amoebocyte lysate assay is used for the detection of and explain in detail?
Limulus amebocyte lysate (LAL) is an aqueous extract of blood cells (amoebocytes) from the Atlantic horseshoe crab, Limulus polyphemus. LAL reacts with bacterial endotoxin lipopolysaccharide (LPS), which is a membrane component of gram-negative bacteria.LAL test is widely used for the detection and quantification of bacterial endotoxins. Ref: Ananthanaryanan 9th ed pg 78