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What is Earliest sign In hepatic encephalopathy is - and explain in detail?
<p>Davidson&;s principles and practice of medicine 22nd edition. *Earliest features are very mild and overlooked but as the conditions become more severe ,apathy ,inability to concentrate,confusion,disorientation,drowsiness,slurring of speech and eventually coma developed.Examination usually shows a flapping tremor (asterixis),inability to perform simple mental arithmetic task or to draw objects such as a star (constructional apraxia).</p>