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What is Persistent truncus aeriosus leads to: and explain in detail?
TRUNCUS AERIOSUS: - Single aerial trunk arises from hea & supplies - systemic, pulmonary & coronary circulations. VSD is always present with it. - Associated with DiGeorge syndrome - deletion of large region of 22q11 - Clinical features: Immediate new born period - Hea failure is absent. Murmur & minimal cyanosis are only initial findings Next 1-2 months of life - Hea failure is seen d/t increased pulmonary circulation; but still minimum cyanosis is present Wide pulse pressure & bounding pulses are seen Systolic ejection murmur sometimes accompanied by thrill - audible along left sternal border - Diagnosis: ECG - shows right, left / combined ventricular hyperophy X-ray - Cardiac enlargement in 1st week of life - Increased pulmonary vascularity after 1st few weeks of life - pulmonary plethora Echocardiography: Diagnostic & demonstrate large truncal aery overriding VSD & pattern of origin of pulmonary aeries. - It is Ductus independent.