You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Lactic acidosis is common with: and explain in detail?
Small increase in blood lactate occurs with metformin but lactic acidosis is rare because it is poorly concentrated in hepatic cells. phenformin has been withdrawn from the market due to risk of lactic acidosis (REF.Essential of medical pharmacology K D TRIPATHI 6 Edition, Page No - 269)