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What is Intrinsic causes of hemolytic anemia are all except- and explain in detail?
Intrinsic causes of hemolytic anemias are due to defective RBCs which includes- Hereditary spherocytosis,Hereditary elliptocytosis, Hmp shunt enzyme deficiency(G6PD deficiency), glycolytic enzyme (pyruvate kinase )deficiency, thalassemia, sickle cell disease . While in hyper splenism RBCs are destroyed by sequestraion which is an extrinsic cause. Ref : Robbins pathologic basis of disease edition :9 pg 630 ; table 14-1