You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A hypertensive patient with BP 160/90 mm of Hg presents with increased level of Lipoprotein a. Which Hypolipidemic drug will you prescribe? and explain in detail?
Ans: (c) NiacinRef: SN Narasingan, Newer Lipid Guidelines: Interpretation and Applications for Indians. ttp://www.apiindia.org/pdf/medicine_update_2017/mu_155.pdfNiacin is the only drug that lowers lipoprotein (a).So, niacin may be preferable for individuals with lipoprotein (a) elevations.It causes maximum HDL increase among drugs used in dyslipidemia treatment.Other options:FenofibrateIt is a fibric acid derivative, acting through PPAR alpha receptor and activates lipoprotein lipase.It reduces triglycerides.PitavastatinHMG CoA Reductase inhibitor.Causes maximum reduction of LDL.EzetimibeIt is a cholesterol ester transport inhibitor, inhibiting transport of cholesterol from intestine to circulation.It is used along with statins.