You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Pecentage of dose given as Basal insulin in bolus basal regimen in children is ? and explain in detail?
A basal-bolus injection regimen involves taking a number of injections through the day. A basal-bolus regimen, which includes an injection at each meal, attempts to roughly emulate how a non-diabetic person&;s body delivers insulin. Intensive therapy includes the administration of insulin 3 times daily by multiple daily injections (MDI) or pen, or an external pump. Every dose of insulin is adjusted according to the pre-meal blood glucose performed at least four times daily, dietary intake, and anticipated exercise. It does not refer to the type of insulin. Total daily dose is divided as follows: * Basal dose: 25-30% of the total dose in toddlers and 40-50% in older children, given at bedtime. This suppresses the glucose production between meals and overnight. * Bolus doses: Remaining dose is divided into 3 pre-meal doses. The meal time (prandial) doses limit post-prandial hyperglycemia. Every bolus dose of insulin is adjusted as per the scale in Table I. Intensive therapy includes the administration of insulin 3 times daily by multiple daily injections (MDI) or pen, or an external pump. Every dose of insulin is adjusted according to the pre-meal blood glucose performed at least four times daily, dietary intake, and anticipated exercise. It does not refer to the type of insulin .Total daily dose is divided as follows: * Basal dose: 25-30% of the total dose in toddlers and 40-50% in older children, given at bedtime. This suppresses the glucose production between meals and overnight. * Bolus doses: Remaining dose is divided into 3 pre-meal doses. The meal time (prandial) doses limit post-prandial hyperglycemia. Every bolus dose of insulin is adjusted as per the scale in Table I. TABLE I Subcutaneous Basal-Bolus Insulin Dosing and Glycemic Targets Age group (years) Target pre-meal blood sugar* Target HbA 1c (mg%) Dose** (U/kg/d) 0-6 100-180 7.5-8.5%+ 0.6-0.7 6-12 90-180 <8% 0.7-1.0 13-19 80-130 <7.5% 1.0-1.2 Reference: GHAI Essential pediatrics, 8th edition