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What is How many bacilli should be there in the tissue for slit skin smear to be positive for Hansen's disease? and explain in detail?
Ref: Rook s Textbook of DermatologyExplanation:At least 1114 bacilli should be present per gram tissue for 1+ bacteriological index in slit skin smear,Maximum number of bacilli in a highly bacillated lepromatous leprosy patient is 1012.Average density of bacilli in lepromatous leprosy is 2.5 billion per 1 cm3 tissue.