You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A 6 year old male child presented with deterioration of renal functions. On examination, he is mentally retarded and has got athetosis. There are multiple healed wounds on his body. His mother reassures you that it was as a result of self inflicted injuries. USG showed bilateral renal calculi. Which of the following statements is FALSE regarding the above mentioned condition? and explain in detail?
Lesch - Nyhan syndrome is an X linked recessive condition and is seen in males. In this condition there is complete lack of hypoxanthine guanine phosphoribosyl transferase. This causes the accumulation of both hypoxanthine and guanine, it is subsequently metabolised to xanthine and finally to uric acid. In Kelley - Seegmiller syndrome occurs due to paial deficiency of HP. Ref: Essential revision notes for MRCP by Philip A Kalra, Edition 3, Page 323