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What is Toll like receptors, recognize bacterial products and stimulates immune response by: and explain in detail?
Toll-like receptors They are membrane proteins that recognize a variety of microbe-derived molecules and stimulate innate immune responses against the microbes. These derive there name due to homology to a Drosophila protein called 'Toll'. The Toll-like receptors are expressed on many immune cells of the body. Signaling by Toll-like receptors results in the activation of transcription factors, notably NF-kB and AP-1.