You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which is the most efficacious treatment of Mesial emporal lobe epilepsy syndrome? and explain in detail?
Mesial temporal lobe epilepsy is due to hippocampal sclerosis. These patients have epilepsy refractory to medical therapy and hence need devices like vagal nerve stimulation. Definitive treatment involves 1. Resection of Antero-medial temporal lobe or limited removal of hippocampus and amygdala (Amygdalo hippocampectomy) 2. Focal seizures, abolished by focal neo coical resection with removal of identified lesion (Lesionectomy).