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What is Pyridoxine deficiencies is seen in - and explain in detail?
Ans. is 'a' i.e., Isoniazid o Alcoholism and isoniazid are contributing factors for pyridoxine deficiency. o Clinical findings of pyridoxine deficiency are seborrhea, glossitis, convulsions, neuropathy, depression, confusion, microcytic anemia. Contributing factors to deficiency of other vitamins. o Thiamine --> Alcoholism o Niacin --> Alcoholism, Vit B6 deficiency, Riboflavin deficiency. o Folate --> Alcoholism, sulfasalazine, pyrimethamine, triamterene. o VitB12 --> Gastric atrophy (pernicious anemia), terminal ileal disease, strict vegetarian o VitC --> Smoking, alcoholism. o Vit A --> Fat malabsorption, Protein energy malnutrition, Infection, measles, alcoholism. o VitD --> Aging, lack of sunlight exposure, fat malabsorption. o VitE --> Fat malabsorption, genetic abnormalities of vit E transpo / metabolism. o VitK --> Fat malabsorption, liver disease, antibiotic use.