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What is The number of cafe au lait macules as one of the diagnostic criteria for adult a neurofibromatosis is - and explain in detail?
Ans. is 'd' i.e., > 6 o Presence of six or more cafe-au-lait macules constitutes one of the diagnostic criterias for diagnosis of neurofibromatosis (Type-1).Diagnostic criteria for Neurofibromatosis 1 (NF1)o The patient should have two or more of the following :Six or more cefe-au-lait spots :# 1[?]5 cm or larger in individuals past puberty.# 0[?]5 cm or larger in individuals before puberty.o Two or more neurofibromas of any type, or one or more plexiform neurofibromas, o Two or more Lisch nodules (benign iris hamartomas),o Freckling in the axilla or groin.o Optic glioma (tumor of the optic pathway).o A distincive bone lesions :# Dysplasia (abnormal development) of the sphenoid bone.# Dysplasia or thinning of long bone cortex.o A first degree relative with NFL