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What is Dietary cholesterol is transpoed from intestine to liver by: and explain in detail?
Dietary cholesterol is transpoed from intestine to liver with the help of Apo-E Dietary lipids (TG +cholesterol) is transpoed from intestine to blood chylomicron. Chylomicron acquires apo E from HDL in circulation. They later get conveed to chylomicron remnants after the action of lipoprotein lipase. Apo-E is the ligand for chylomicron remnants for uptake by liver which brings dietary cholesterol from the intestine to the liver. Even though chylomicron contain Apo B48 mainly, but uptake of chylomicron remnant in liver is due to Apo E. Therefore, Apo E is the answer here.