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What is Function of hepatic kupffer cells is and explain in detail?
Kupffer cells Kupffer cells, derived from the macrophage - monocyte system Are irregular stellate - shaped cells that also line the sinusoids, insinuating between endothelial cells Phagocytic, play a major role in the trapping of foreign substances and initiating an inflammatory response MHC-II antigens are expressed on kupffer cells but do not confer efficient antigen presentation compared with macrophages elsewhere in the body Ref: Sabiston 20th edition Pgno :1430