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What is Which of the following feature differentiates pethidine from morphine? and explain in detail?
In contrast to morphine, pethidine has following features 1/10 analgesic potency More rapid onset of action Shoer duration of action Not an effective cough suppressant Lesser spasmodic action on smooth muscles Local anesthetic action Less histamine relief - safer in asthmatics Higher oral; parenteral activity ratio Atropinic effects - dry mouth, blood vision Miosis, constipation Urinary retention are less prominent.