You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is The indicator of active multiplication of Hepatitis B virus is: and explain in detail?
HBsAgAnti HBsAnti HBcHBeAgAnti-HbeInterpretation+-IgM+-Acute hepatitis B, high infectivity+-IgG+-Chronic hepatitis B, high infectivity+-IgG-+1. Late acute or chronic hepatitis B, low infectivity2. HBeAg-negative ("precore-mutant") hepatitis B(chronic or, rarely, acute++++/-+/-1. HBsAg of one subtype and heterotypic anti-HBs(common)2. Process of seroconversion from HBsAg to anti-HBs (rare)--IgM+/-+/-1. Acute hepatitis B2. Anti-HBc "window"Diagnostic approach in Patients with HepatitisHBs AgIgm Anti -HAVIgm Anti HBCAnti HCVDiagnostic Interpretation+-+-Acute hepatitis B +---Chronic Hepatitis B++--Acute Hepatitis A superimposed on Chronic Hepatitis b+++-Acute Hepatitis A and B-+--Acute hepatitis A-++-Acute Hepatitis A and B--+-Acute Hepatitis B---+Acute hepatitis CRef: Harrison's 18/e p2550 17/e p1933