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What is A 1-week-old neonate presents to the pediatric emergency room with fever, irritability, poor feeding, and a bulging anterior fontanelle. Lumbar puncture is performed, and the cerebrospinal fluid (CSF) grows group B Streptococcus. Which of the following is the most likely pathogenic mechanism? and explain in detail?
There has been speculation concerning the pathogenesis of GBS. This includes failure to activate complement pathways and immobilization of polymorphonuclear leukocytes due to the inactivation of complement C5a, a potent chemoattractant.