You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is 40-year-old immunocompromized patient presented with complaints of dysphagia. UGI scopy showed multiple ulcers in the distal esophagus. Biopsy from the esophagus showed the following. What is the diagnosis? and explain in detail?
Ans. (b) Cytomegalovirus(Ref: Robbins 9th ed p 755)CMV causes shallower ulcerations and characteristic nuclear and cytoplasmic inclusions within capillary endothelium and stromal cells. Infected cells are strikingly enlarged, often to a diameter of 40 m, and show cellular and nuclear pleomorphism. Prominent intranuclear basophilic inclusions spanning half the nuclear diameter are usually set off from the nuclear membrane by a clear halo