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What is Inhibits mitosis by forming microtubules - and explain in detail?
Ans. is 'b' i.e., Docetaxel Taxanes (Paclitaxel and Docetaxel) enhances polymerization of tubulin (a mechanism opposite to that of vinca alkaloids) --> the microtubules are stabilized and their depolymerization is prevented. Vinca alkaloids (vincristine, vinblastine) prevent polymerization and assembly of microtubules.