You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A 60 year old male presents with features of atypical parkinsonism in conjunction with cerebellar signs and early and prominent autonomic dysfunction, usually ohostatic hypotension is MOST likely suffering from: and explain in detail?
Multiple-system atrophy (MSA) manifests as a combination of parkinsonian, cerebellar, and autonomic features. Clinically, MSA is suspected when a patient presents with atypical parkinsonism with cerebellar signs and early autonomic dysfunction, usually ohostatic hypotension. Ref: Harrisons Principles of Internal Medicine, 18th Edition, Page 3318