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What is Which of the following antimicrobial agents do not require reduction in dose in patients with renal failure? and explain in detail?
Rifampicin is primarily metabolized in the liver and excreted in bile. Rifampicin does not require dosage adjustment in Renal failure. Ref: Essentials of Medical Pharmacology By K D Tripathi, 5th Edition, Pages 667, 700, 719, 721; KDT 6th Edition, Page 741