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What is SGPT is found in: and explain in detail?
SGPT and SGOT are found in cytoplasm of hepatocytes whereas SGOT is also found in mitochondria of hepatocytes. SGPT can be raised in other forms of tissue damage, such as: Myocardial infarction Muscle necrosis Renal disorders Cerebral disorders Intravascular hemolysis. In these diseases, serum SGOT levels are much higher than SGPT levels. However, in liver disease, generally SGPT increases more than SGOT.