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What is GLUT responsible for secretion of insulin from beta cells of pancreas and explain in detail?
Glucose transpoer 2 (GLUT2) also known as solute carrier family 2 (facilitated glucose transpoer), member 2 (SLC2A2) is a transmembrane carrier protein that enables protein facilitated glucose movement across cell membranesGLUT2 has high capacity for glucose but low affinity (high Km, ca. 15-20 mM) and thus functions as pa of the "glucose sensor" in pancreatic b-cells. It is a very efficient carrier for glucose.Ref: DM Vasudevan, 7th edition