You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is O2 dissociation curve is shifted to right in all except- and explain in detail?
Ans. is 'd' i.e., Metabolic alkalosis o Hypercapnea (raised CO2), rise in temprature and increased 2, 3 DPG cause righward shift of O2 dissociation curve,o Metabolic alkalosis causes leftward shift.o Alkalosis (increased pH), increased HbF, and hypothermia (decrease in temperature) cause a leftward shift of oxygen dissociation curve, i.e. increase oxygen affinity to hemoglobin,o Hypoxia (with decrease PaO,) causes a rightward shift of the curve, i.e. decreased oxygen affinity to hemoglobin.Ox Veen dissociation curveShifted to rightShifted to lefto Decreased oxygen affinity' to hemoglobino Increased P50o Increased oxygen delivery to tissueso Causes :y Decreased pH (Acidosis)y Increased temperaturey Increased PCO,y Increased 2,3 DPG (BPG)i) Growth hormone. Androgen, thyroid hormoneii) Exerciseiii) Tissue hypoxiaiv) High altitudev) Anemiavi) Alkalosisvii) Cyanotic CHDviii) Pregnancyix) Chemicals : E no sine, Pyruvate, PEP, phosphateySickle hemoglobin (HbS)o Increased oxygen affinity to hemoglobino Decreased P50o Decrease oxygen delivery to tissueso Causes :y Increased pH (alkalosis)y Decreased temperaturey Decreased PCO,y Decreased 2,3 DPG (BPG)Stored bloody Fetal hemoglobin (HbF)