You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A 32-year-old female, asymptomatic, not requiring blood transfusion, presents with Hb 13.0 gm/dl. Her HbF levels are 95%, HbA2, 1.5%. Which of the following is the most likely diagnosis - and explain in detail?
<p>In contrast to alpha thalassemia ,gene deletion rarely ever causes beta thalassemia & is only seen in an entity called hereditary persistence of foetal hemoglobin (HPFH).</p><p>In the given case scenario ,HbA2 is within normal limit (1.5-3.5%) in contrast to thalassemia where the HbA2 will be increased .</p><p>Reference :Harsh mohan textbook of pathology sixth edition pg no 322.</p>