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What is Which of the following calcium channel blocker has a predominant peripheral action: September 2006 and explain in detail?
Ans. C: Nifidepine Sublingual nifedipine has previously been used in hypeensive emergencies. This was found to be dangerous, and has been abandoned. Sublingual nifedipine causes blood-pressure lowering through peripheral vasodilation. It can cause an uncontrollable decrease in blood pressure, reflex tachycardia, and a steal phenomenon in ceain vascular beds