You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A 50 year old male presented with history of hematemesis - 500ml of blood and on examination shows BP- 90/60, PR-110bpm and splenomegaly 5cm below lower costal margin. Most probable diagnosis is and explain in detail?
Splenomegaly and massive bleeding leading to hypotension are in our of poal hypeension. Common causes of upper Gastrointestinal Hemorrhage Non-variceal bleeding (80%) Poal Hypeensive Bleeding (20%) Peptic ulcer disease (MC) 30-40% Gastroesophageal varices >90% Malory-weiss tear 15-20% Hypeensive poal gastropathy <5% Gastritis or duodenitis 10-15% Isolated gastric varices <5% Esophagitis 5-10% Aeriovenous malformations 5% Tumors 2% Others 5% Ref: Sabiston 20th edition Pgno : 1142