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What is Minimum hCG level that a urine pregnancy test can detect is? and explain in detail?
5 m IU/ ml REF: Danfoh's Obstetrics and Gynecology, 10th Edition page 4, Current OB/GYN > Chapter 9. Normal Pregnancy & Prenatal Care > Normal Pregnancy > URINE PREGNANCY TEST: Sensitive, early pregnancy test measure changes in levels of hCG. There is less cross-reaction with luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyrotropin, which all share common a subunit with hCG, when the /3 subunit of hCG is measured. hCG is produced by the syncytiotrophoblast 8 days after feilization and may be detected in the maternal serum after implantation occurs, 8-11 days after conception. hCG levels peak at approximately 10-12 weeks of gestation. Levels gradually decrease in the second and third trimesters and increase slightly after 34 weeks. The half-life of hCG is 1.5 days. After termination of pregnancy levels drop exponentially. Normally, serum and urine hCG levels return to nonpregnant values (< 5 m U/mL) 21-24 days after delivery. hCG is measured in milli-international units per milliliter (m IU/ml) The detection of greater than 35 m IU of human chorionic gonadotropin (hCG) in the first morning void has a very high specificity for pregnancy /3 Hcg in m IU/m1 Result Under 5 m IU/ml Negative- Not pregnant Between 5-25 m IU/ml: "Equivocal"- Maybe pregnant may not be- Repeat test Over 25 m IU/ml Positive- Pregnant