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What is Most important buffer system in human blood: and explain in detail?
Ans. a (Bicarbonates); (Ref. Ganong, Physiology, 21st ed., 736; Satyanarayan, Biochemistry 2nd ed. - 525)PRINCIPAL BUFFERS IN BODY FLUIDSBlood1. H2CO3 K H+ +HCO-3 (Bicarbonate buffer) =>>most predominant buffer of ECF. especially blood plasma.2. HProt K H+ + Prot- & HHb K H++ Hb- (Protein buffer)3. H2PO4 - KH-+ HPO42- (Phosphate buffer)Interstitial fluid1. H2 CO3 K H+ + HCO-3Intracellular fluid1. HProt K H+ + HCO 32. H2PO4 - KH-+ HPO42-