You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Takayasu disease most commonly affects? and explain in detail?
TAKAYASU'S AERITIS This inflammatory disease often affects the ascending aoa and aoic arch, causing obstruction of the aoa and its major aeries. It also may involve the descending thoracic and abdominal aoa and occlude large branches such as the renal aeries. Aoic aneurysms also may occur. ( Harrison&;s principle of internal medicine,18th edition,pg no. 2065)