You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Commonly used route of administration for general anaesthesia is and explain in detail?
Ans. b (Intravenous). (Ref: Anesthesia by Ajay Yadav 2nd/pg. 71; KD Tripathi, 5th/pg. 342)INTRAVENOUS ANAESTHESIA# The most commonly used route of administration used for general anesthesia is IV for induction of anesthesia and inhalational agents are preferred for maintenance.# The most commonly used IV anesthetic agent for induction is thiopentone,# Ideal characteristics of IV anesthetics are- Compatible with other dugs- High therapeutic index- Inexpensive- Independent of liver/kidneys for metabolism/excretion- No toxic metabolites- Long shelf life and resistance to microbial contamination- Non-cumulative- Non-allergenic- No cardiopulmonary depression- No effect on cerebral blood flow- No endocrinologic effect- No pain on injection- Quick and smooth induction-recovery- Reversible with specific antagonist- Potent, so small volume is required for anesthetic induction/maintenanceIV Anesthetic agents:BarbituratesNon-barbituratesDissociatives- Oxybarbiturate - pentobarbital and methohexital- Thiobarbiturates - thiopental and thiamylal- Propofol- Etomidate- Alphaxalone- PropanididKetamineTiletamine