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What is At what gestational age is RU-486, an anti-progesterone drug used in the induction of aboion? and explain in detail?
Mifepristone RU-486 is an analogue of progestin (norethindrone) which act as an antagonist, blocking the effect of natural progesterone. This when used along with prostaglandin E1 is used in first trimester aboion. It is highly successful when used within 50 days of gestation. Ref: Textbook of Obstetrics By D.C.Dutta, 6th Edition, Page 175 ; Clinical Gynaecology By T. F. Kruger, 3rd Edition, Page 358