You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is b-blockers act in glaucoma by - and explain in detail?
Ans. is 'a' i.e., Decreased aqueous production Mechanism of action of pharmacological agents in POAGAgentMechanism of actiono b-blocker (Timolol. Betaxolol, levobunolol, carteolol)o Decreased aqueous secretion from ciliary epitheliumo Prostaglandins (latanoprost, bimatoprost, travoprost)o Increased uveosclerai aqueous outflowo Alpha agonists # Non-selective (Epinephrine, Dipivefrine)# Selective a-2 (Aprocionidine, Brimonidme)Increased uveosclerai aqueous outflow.Decreased aqueous secretiono Carbonic anhydrase inhibitors (Dorzolamide, Brinzolamide, Acetazolamide)o Decreased aqueous secretion due to lack of HCOt"o Cholinomimetics (Pilocarpine, physostigmine. carbachot, echothiphate)o Increased aqueous outflow due to opening of trabecular meshwork due to ciliary muscle contractiono Hyperosmotic agents (Mannitol, glycerol)o Reduce vitreous volume and deepen anterior chamber