You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Tolvapton is a/an - and explain in detail?
Ans. is 'c' i.e., Vasopressin antagonist VAPTANSo A new class of medication, the "vaptan drugs", act by inhibiting the action of vasopressin on it receptors (V1A, V1B and V2) - Vasopressin receptor antagonists.# As already explained, V1 A receptors are involved in vasoconstriction - V1A antagonist can be used when total peripheral resistance is increased, e.g. in CHF and hypertension.# Example - Relcovaptan2) V1 B receptor antagonist# V1 B receptors are expressed in brain and pituitary gland - V1 B antagonist can be used as psychiatric drugs.# Example - Nelivaptan3) V2 receptor antagonists# V2 receptors are mainly responsible for increase water permeability in kidney - V2 antagonists can be used when there is excessive ADH induced fluid retention as in SIADH.# Examples - Lixivaptan, satavaptan, mozavaptan, Tolvaptan.4) Non-selective (mixed V1A/V2)# Can be used in CHF# Examples - Conivaptan