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What is Me Ardle's disease is due to deficiency of - and explain in detail?
Ans. is 'a' i.e., Myophosphorylase o Deficiency of muscle phosphorylase (myophosphorylase) causes Me Ardle's disease.Type Enzyme deficiencyOrgan (s) affectedIvon Gierke's diseaseGlucose 6-phosphataseLiver, kidneyIIPompe's diseasea (1 - 4) Glucosidase (acid maltase)All organsIIICori's disease/Forbe's diseaseDebranching enzymeMuscle, liverIVAndersen's diseaseBranching enzymeLiver, myocardiumVMcArdle's diseasePhosphorylaseMuscleVIHers' diseasePhosphorylaseLiverVIITarui's diseasePhosphofructokinaseMuscle, RBCsVIII Phosphorylase kinaseLivero There is also on X-linked form of phosphorylase kinase deficiency. This is sole exception as all other glycogen storage diseases are inherited as autosomal recessive trait.