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What is Mechanism of action of sodium nitrate in cyanide poisoning is and explain in detail?
Sodium nitroprusside contain 1 Iron molecule coordinated to five cyanide molecules and one molecule of nitric oxide Prolonged use of Sodium nitroprusside may cause cyanide poisoning Detoxification occurs when cyanide and methamoglobin combines to form cyanomethamoglobin. Amyl nitrate and sodium nitrates enhance the oxidation of hemoglobin to methamoglobin, ensuring reliable mechanism of detoxification Refer kDT 6/e p 527