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What is Increase in alkaline phosphatase is seen in: and explain in detail?
LAP is found in the membranes of secondary granules of neutrophils. Its activity is measured in mature neutrophils and band cells only. Esinophils donot show alkaline phosphatase activity and must not be mistaken with mature neutrophils with a score of zero.Malaria is characterized by monocytosis.( ref Robbins 8/e p595, 9/e p584)