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What is Which of the following statement is not true regarding dapsone? and explain in detail?
Ans. B. Poor oral absorptionDapsone has good oral absorption and it has a long half-life, averaging 28 hours.Dapsone :* Mechanism of Action: Inhibition of folic acid synthesis* It is weakly bactericidal.* It can cause mild hemolysis in the given doses, rarely anemia or psychosis.DDS syndrome:* It is rarely seen as a side effect of dapsone therapy in leprosy patients.* It starts after 5-6 weeks of starting dapsone and leads to exfoliative dermatitis, hepatosplenomegaly, Lymphadenopathy, fever, and hepatitis and may be fatal.* Dapsone (DDS) syndrome is also called the "five-week dermatitis" because it suddenly occurs five to six weeks after the administration of dapsone.