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What is RNA polymerase has which activity and explain in detail?
DNA synthesis cannot commence with deoxyribonucleotides because DNA polymerase cannot add a mononucleotide to another mononucleotide. Thus, DNA polymerase cannot initiate synthesis of complementary DNA synthesis strand of DNA on a totally single stranded template. For this, they require RNA primer, which is a sho piece of RNA formed by enzyme primase (RNA polymerase) using DNA as a template. RNA primer is then extended by addition of deoxyribonucleotides. Later on, the ribonucleotides of the primer are replaced by deoxyribonucleotides. Primase is actually a DNA primase which has RNA polymerase activity. This DNA primase is also called DNA polymerase.