You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which of the following substrates links urea cycle to Kreb's cycle? and explain in detail?
Arginosuccinate an intermediate of urea cycle is cleaved by argininosuccinate lyase to arginine and fumarate. This fumarate formed in the urea cycle can be funnelled into TCA cycle to be conveed to malate and then to oxaloacetate. Oxaloacetate formed in the krebs cycle can be transaminated to aspaate which is an intermediate of urea cycle. Ref: Textbook of Biochemistry By D M Vasudevan, 3rd Edition, Page 161