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What is Which Which of the following statement is TRUE about Bohr&;s effect? and explain in detail?
The decrease in O2 affinity of hemoglobin when the pH of blood falls is called the Bohr effect. It is closely related to the fact that deoxygenated hemoglobin (deoxyhemoglobin) binds H+ more actively than does oxygenated hemoglobin (oxyhemoglobin). The pH of blood falls as its CO2 content increases, so that when the PCO2 rises, the curve shifts to the right and the P50 rises. REF: GUYTON 12TH ED