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What is All are true about hepatitis A except and explain in detail?
Hepatitis A virus (HAV):HAV is a 27-nm, non-enveloped RNA virus belonging to picornavirus family. It was originally designated as 'enterovirus 72'. Because of its unique features, HAV is now recognized as the prototype of a new genus Hepatovirus. HAV can be grown in some human and simian cell cultures and is the only human hepatitis virus which can be cultivated in vitro. Chronic carriers are not seen. Serological diagnosis: IgM HAV, HAV RNA. Prophylaxis: Improved sanitary practices and prevention of fecal contamination of food and water. A safe and effective formalin inactivated, alum conjugated vaccine containing HAV grown in human diploid cell culture is available. A full course consists of two intramuscular injections of the vaccine. Protection begins 4 weeks after injection and lasts for 10-20 years.(Ref: Ananthanarayan 9th edition, p541)