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What is Treatment of pustular psoriasis is:- and explain in detail?
Most cases of GPP (Generalised Pustular Psoriasis) require systemic therapy. Retinoids--> TOC Response to high doses of acitretin (1 mg/kg/day) is rapid and lower doses of 0.5-0.75 mg/kg/day, sufficient to maintain control. Acitretin> Methotrexate Other drugs used are Cyclosporine ,Colchicine, Razoxane, Dapsone TNF-antagonists, and Basiliximab, an antibody directed at the IL-2 receptor, rapidly control acute GPP. Systemic steroids are C/I in psoriasis.