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What is Which of the following represents the marked area in the histology of lymph node? and explain in detail?
Ans. (a) Mantle zone(Ref: R 9/p 583)A normal lymph node has 2 areas: Cortex - Lymphoid follicles and paracortical areas, Medulla - predominantly blood vesselsStructures in a FollicleGerminal center: Round/oval zone containing pale staining cells, surrounded by darker cellsMantle zone: Small dark coloured unchallenged B cells surrounding pale staining germinal centersMarginal zone: Light zone surrounding follicles; contains postfollicular memory B cells derived after stimulation of recirculating cells from T cell dependent antigen; named "marginal cells" due to location