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What is In treatment of shock Dobutamine is preferred over Dopamine because? and explain in detail?
ANSWER: (D) All of the aboveREF: KDT 5th edp.470DopamineActs on D1 , D2 , alpha and betal receptorsLow doses: renal vasodilation (D1 action)Moderate doses: Positive ionotropism (betal action) High doses: Vasoconstriction ( alphal action)DobutamineRelatively betalspecific agonistIonotropic i.e increases force of cardiac contraction without causing vasoconstriction . increasing afterload, heart rate or BP.Therefore since dobutamine is betal specific, doesn't cause vasoconstriction, it is less arrythmogenic, and doesn't affect renal vasculature it is preferred in cardiogenic shock, however it is less suitable for shocks in which vasoconstriction is required.