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What is Anti-influenza drug which is/are given through inhalation route ? and explain in detail?
Ans. C. ZanamivirAnti-influenza drugsAmantadine, rimantadine, oseltamivir and zanamivir.Only zanamivir is given by parenteral route (intranasd or intravenous). all others are given orally.Zanamivir has lowest oral bioavailability lowest t1/2 (shoest acting).Rimantadine has maximum plasma protein binding, while oseltamivir has minimum plasma protein binding.Rimantadine has maximum metabolism.