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What is The most impoant mechanism by which gram negative bacilli acquire chloramphenicol resistance is: and explain in detail?
Resistance to chloramphenicol is usually by a plasmid encoded enzyme acetyltransferase which inactivates the drug. it can also be due to decreased permeability of the drug into the cell and also due to ribosomal mutation. Antimicrobial resistance through inactivating enzymes develops against: A: Aminoglycosides B: Beta lactams C: Chloramphenicol