You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Diuretics cause loss of: and explain in detail?
Complications of high ceiling and thiazide type diuretic therapy - Hypokalaemia 
This is the most significant problem. It is rare at low doses used for hypertension, but may be of grave consequence, when brisk diuresis is induced or on prolonged therapy, especially if dietary K+ intake is low. 
Degree of hypokalaemia appears to be related to the duration of action of the diuretic; longer acting drugs cause more K+  loss. 
Hypokalemia is less common with standard doses of high ceiling diuretics than with thiazides, possibly because of shorter duration of action of the former, which permits intermittent operation of compensatory repletion mechanisms. Hypokalaemia can be prevented and treated  by: 
(a)  High dietary K+ intake  or 
(b) Supplements of KCl  (24- 72 mEq/day) or
(c)  Concurrent use of K+ sparing diuretics.
Reference: Essentials of Medical Pharmacology Eighth Edition KD  TRIPATHI  page no 631