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What is All of the following statement about pralidoxime in organophosphate poising are true except and explain in detail?
- Oximes are given for the reactivation of the inhibited Acetylcholinesterase in OPC poisoning - Two oximes which are used : * PAM (Pralidoxime) : does not cross blood brain barrier * DAM (Diacetyl mono-oxime) : crosses blood brain barrier, both central and peripheral action - Oximes should be staed as soon as possible after atropine is given , if we take long time then enzyme aging may occur (enzyme cannot work)