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What is Severe combined immunodeficiency is seen with: and explain in detail?
Ans. (c) BothRef Microbiology by Ananthanaray an and Paniker 9th ed. 174* Severe combined immunodeficiency (SCID) syndrome has impairment of both humoral and cell mediated immunity (B and T cell defect).* Inheritance pattern of SCID is X-Iinked recessive > Autosomal recessive.Clinical Manifestation of SCID* Oral candidiasis in infants* Recurrent infection with candidia albicans, RCarinii, CMV, varicella.* Organs like lymph nodes, tonsils, peyers patches are absent.* Very small thymus gland* Poor survival rate.