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What is A 45-year-old female, known case of Irritable bowel syndrome presented with a poorly localized pain especially involving the axial skeleton. The pain was severe, associated with tenderness, and had been occurring for the past 4 months. She also repoed fatigue, stiffness, sleep disturbance, cognitive dysfunction, anxiety, and depression. Lab and radiographic studies were normal and didn't reveal any abnormalities. All of the following drugs are approved for the above condition EXCEPT: - and explain in detail?
This is a case of fibromyalgia. It is a syndrome of musculoskeletal pain and tenderness along with neuropsychiatric symptoms. It is a chronic disease. It is associated with chronic fatigue syndrome, temporomandibular syndrome, chroni c headaches and irritable bowel syndrome. It is more common in females in ratio of 9:1. Drugs approved are: - 1. Muscle relaxant (Cyclobenzaprine) 2. SSRIs (Duloxetine, Amitriptyline, Milcipran) 3. Anticonvulsants: -Pregabalin 4. Analgesic: - Tramadol