You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Substance (s) freely filtered across glomerular capillaries : (PGI Nov 2009) and explain in detail?
Ans: A (Glucose) Filtereability of SolutesFilterability of solutes is inversely related to their size. Substance are freely filtered by glomerulus as water when filterability is of 1.0QIf the size of molecules approaches to that of albumin, filterability decreases approaching zeroSome low molecular wt. substance e.g. calcium and fatty acids are not freely filtered.Na. Inulin & glucose are freely filteredQ (filterability = 1).* Albumin, myoglobin ore not freely filteredQTable (Guyton) : Filtereability of Substances by Glomerular Capillaries Based on Molecular WeightSubstanceMolecular WeightFilterabiltiyWater181.0Sodium231.0Glucose1801.0Inulin5,5001.0Myoglobin17,0000.75Albumin69,0000.005Also RememberNegatively charged large molecules are filtered less easily than positively charged molecules of equal molecular size[Guyton 11th/ 317)