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What is Calculate the loading dose of a drug whose systemic bioavailability will be 20%, Vd-200L and target concentration is 5gm/L and explain in detail?
In pharmacokinetics, a loading dose is an initial higher dose of a drug that may be given at the beginning of a course of treatment before dropping down to a lower maintenance dose Loading dose-= 1000/20=5 Ref: KD tripathi 8th ed