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What is The hypothalamus produces several releasing peptides. Which releasing peptide is responsible for the release of adrenocoicotropin (ACTH) from the pituitary? and explain in detail?
Coicotropin releasing factor (CRF) released from the hypothalamic paraventricular nucleus is responsible for release of ACTH. The cell type within the paraventricular nucleus is termed the parvicellular or small neurons. These neurons project their axons into the tuberohypophyseal tract to be released into the hypothalamo hypophyseal poal system to act on the pituitary. Ref: Javorsky B.R., Aron D.C., Findling J.W., Tyrrell J.B. (2011). Chapter 4. Hypothalamus and Pituitary Gland. In D.G. Gardner, D. Shoback (Eds),Greenspan's Basic & Clinical Endocrinology, 9e.