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What is True statement about Antistreptolysin ‘O’ titre is: and explain in detail?
Retrospective Diagnosis of Streptococcal infection

ASO (Anti Streptolysin ‘O’) titre :

– Estimation of antibody aganist streptolysin is a standard serological test for retrospective diagnosis of streptococcal infection.
– ASO titre > 200 are indicative of prior streptococcal infection.
– Raised after throat infection only
– Acute rheumatic fever :
- High level of ASO titre are usually found
- Titres > 300 or 350 are taken as significant.
– Acute glomerulonephirits :
- ASO titres are often low.

Streptozyme test – Passive slide hemaglutination test

Becomes positive after nearly all types of streptococcal infection whether of throat or skin.

Anti DNA ase B and Antihyaluronidase – Useful for retrospective diagnosis of Streptococcal Pyoderma or for acute glomerulogephritis for which ASO titre is of much less value