You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Fatty liver with Hepatomegaly is seen in:- and explain in detail?
Metabolic syndrome: Central obesity Insulin resistance Hyperglycemia Risk of dyslipidemia Diabetes On HPE examination of fatty liver, macro vesicular steatosis is seen. Lipid accumulates inside hepatocytes forming vacoules which gives clear appearance on staining. Wilson's disease: ATP 7B gene defect Body retains excess copper Kayser Fleischer ring ( Brown ring on the edge of cornea) Thesunflowercataract inWilson's disease is pathognomonic sign . Predominant presentation includestremor, dysphasia, ,dysahria , neuropsychiatric manifestations , gait and limb ataxia Nutmeg liver: Associated with chronic venous congestion of liver Dark spots represent dilated and congested hepatic venules and small hepatic veins Marasmus: Due to deficiency of proteins and calories Lean appearance Oedema is absent No fatty liver