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What is Whorled keratopathy is seen with the use of: and explain in detail?
Ans: B (Amiodarone) Ref: kanski 7th edition Clinical Ophthalmology page no 862 - 863Explanation:Vortex Keratopathy/ CorneaverticillataCharacterized by whorl like corneal epithelial depositsIn chronological order it starts as bilateral brow n opacities in the inferior cornea - whorl like patternDRUGS-Antimalarials - chloroquine & hydrxychloro- quineNo relationship with dosage or durationReversible on cessation of therapyOther ocular manifestations - Cataract, bull's eye retinopathyAMIODARONE - anti arrhythmic drugDeposits are more in high dose usage & longer duration usage: but slowly reversible with cessation of amiodaroneOther ocular manifestations - Anterior subcapsular lens deposits. Optic neuropathy