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What is A patient with acute history of blistering and denudation involving >30% BSA along with erosions of the lips with hemorrhagic crusting and other mucosa for few days. What is the most common triggering factor? and explain in detail?
Lesions >30% BSA , erosion over lips and mucosa : Dx TEN TEN SJS: Haemorrhagic Crusting Sloughing of mucosa Targetoid lesion (2 rings) Nikolsky sign (Pseudo) due to epidermal necrosis. Epidermal necrosis (SJS/TEN) Etiology: Drugs: -Antiepileptic( MC) - CBZ, Lamotrigine * NSAIDS * Penicillin * Nevirapine CBZ induced SJS/TEN is a/w HLA B1502