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What is Main mechanism of combined OCP? and explain in detail?
Ans. A. Feedback inhibition of pituitary (causing of LH surge)The estrogen provides a negative feedback on the release of FSH and LH by the pituitary. The progestin inhibits LH release. Both synergize to inhibit MID cycle LH surge. As a result, ovulation does not occur. Interference with ovulation is the most common pharmacologic mechanism for preventing pregnancy