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What is Hepcidin associated with which molecule? and explain in detail?
Ans. is 'a' i.e., Iron Hepcidin is a positive acute phase reactant. Hence during inflammation, liver releases more hepcidin. This inhibits basolateral side transpo of iron along intestine. This results in a hematological picture which mimics iron deficiency anemia. This is the basis of Anemia of Chronic Disease