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What is The triad of "saturnine" gout, hypeension and renal insufficiency seen in poisoning with which of the following metals? and explain in detail?
Heavy metals like cadmium and lead can lead to chronic tubulointerstitial disease. It is usually not commonly diagnosed. This leads to proximal tubular damage and hyperuricemia due to diminished urate excretion. The above mentioned triad should prompt a clinician to ask specifically about lead exposure. Lead chelation therapy can slow the disease progression.