You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Black necrotic mass seen in the nose of a elderly diabetic patient. Most probable diagnosis - and explain in detail?
Ans. is 'c' i.e., Mucormycosis o Mucormycosis is fungal infection of nose and paranasal sinuses which may prove rapidly fatal if untreated.o It is seen in uncontrolled diabetics or in those taking immunosuppressive drugs.o From the nose and sinuses, infection can spread to orbit, cribriform plate, meninges and brain.o The rapid destruction associated with the disease is due to affinity of fungus to invade the arteries and cause endothelial damage and thrombus.o It presents as black necrotic mass filling the nasal cavity and eroding the septum and hard palate.o Treatment is by amphotericin B and surgical debridement.