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What is The following drug penetrates into caseous necrosis in TB- and explain in detail?
Ans- B RIFAMPICIN: 1.most effective anti- tubercular drug 2.Most bactericidal antitubercular drug 3.Only bactericidal drug effective against persisters or dormant bacilli in solid caseous lesson 4.Acts on extracellular as well as intracellular organisms 5.Antitubercular drug causing rapid sputum conversion 6.Antitubercular drug causing orange discoloration of urine ISONIAZID: 1.First effective bactericidal drug used to treat tuberculosis 2.Maybe bacteriostatic at lower concentrations 3.Most toxic antitubercular drug 4.Antitubercular drug first to develop resistance STREPTOMYCIN: 1.Injectable antitubercular drug 2. Antitubercular drug contraindicated in pregnancy 3.Antitubercular drug causing vestibular damage ETHAMBUTOL 1.Antitubercular drug contraindicated in children < 6 years age 2. Antitubercular drug causing Optic neuritis(red-green color blindness)