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What is DOC for prophylaxis against Diphtheria is:- and explain in detail?
Erythromycin is macrolide group of drug which binds irreversibly to a site on the 50s subunit of bacterial ribosome thus inhibiting translocation steps of protein synthesis. It is used to eliminate the carrier state of Corynebacterium Diphtheriae. Rifampicin: Blocks RNA transcription by interacting with B subunit of mycobacterial DNA dependent RNA polymerase.