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What is Most specific antibody seen in RA and explain in detail?
Answer- A. Anti CCPThe presence of serum anti-CCP antibodies has about the same sensitivity as serum RF for the diagnosis of RA.However, its diagnostic specificity approaches 95% (most specific for RA), so a positive test for anti-CCP antibodies in the setting of an early inflammatory ahritis is usefrrlfor distinguishing RA from other forms of ahritis.