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What is Contraction of muscle can be caused by and explain in detail?
The process by which the contraction of muscle is brought about is a sliding of the thin filaments over the thick filaments. STEPS INCLUDE: Discharge of motor neuron.Release of transmitter (acetylcholine) at motor end-plateIncreased Na+ and K+ conductance in end-plate membraneGeneration of end-plate potential.Inward spread of depolarization along T tubulesRelease of Ca2+ from terminal cisterns of sarcoplasmic reticulum and diffusion to thick and thin filaments Formation of cross-linkages between actin and myosin and sliding of thin on thick filaments, producing movement.(REF.GANONG'S REVIEW OF MEDICAL PHYSIOLOGY -23rd EDITION. Page No-100)