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What is Which of the drug Does not have active metabolite and explain in detail?
(Ref KDT 6e p485). Captopril and lisinopril are ACE inhibitors that are not prodrugs. Diazepam produce many active metabolites like.oxazepam. Propranolol can produce 4-hydroxypropanolol .which has b-antagonist activity. Allopurinol gives rise to oxypurinol which can inhibit xanthine oxidase.