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What is Skin lesion in meningococcal meningitidis is due to and explain in detail?
The endotoxin lipopolysaccharide of Meningococci is released by autolysis.- vascular endothelium is paicularly sensitive to the endotoxin. All major inflammatory cascade systems, as well as cytokines and nitric oxide, are triggered and unregulated. Reference: Textbook of Microbiology; Anathanarayan and panicker's; 10th edition; Page no: 232