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What is Most common cause of Budd-Chiari syndrome is: and explain in detail?
Primary Budd-Chiari syndrome (75%): thrombosis of the hepatic vein Secondary Budd-Chiari syndrome (25%): compression of the hepatic vein by an outside structure (e.g. a tumor) The cause for the disease cannot be found in about half of the patients. Hepatic vein thrombosis is associated with the following in decreasing order of frequency: Polycythemia vera": is a primary,absolute erythrocytosis. The EPO levels are suppressed causing alow to normal EPO in the blood. Pregnancy Post paum state Use of oral contraceptives Paroxysmal nocturnal hemoglobinuria Hepatocellular carcinoma Lupus anticoagulant