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What is A 7 year old girl is brought with complaints of generalized swelling of the body. Urinary examination reveals Grade 3 proteinuria and the presence of hyaline and fatty casts. She has no history of Hematuria. Which of the following statements about her condition is TRUE? and explain in detail?
A young girl presenting with generalized edema, significant proteinuria, absence of hematuria and hyaline and fatty casts is most likely to be suffering from Minimal change disease (Lipoid nephrosis), the most common type of Nephrotic Syndrome. In patients with Minimal change disease, C3 levels are normal and renal biopsy does not show any significant abnormalities except obliteration of epithelial foot processes. Therefore, No IgG Deposits or C3 deposition on renal biopsy is the best answer. Ref: Essential Pediatrics By O P Ghai, 6th Edition, Pages 446, 450