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What is Immunoglobulin transpoed through the placenta is and explain in detail?
IgG is the only immunoglobulin class to cross the placenta and therefore is the most abundant immunoglobulin in newborns. Isotype-specific transpo of IgG across the placenta occurs with a preference for IgG1 and IgG3 subclasses.IgG also mediates opsonization of antigen through binding of antigen-antibody complexes to Fc receptors on macrophages and other cells.IgM is a Millionaire molecule, largest. IgA - Secretory Ig. IgE - AnaphylaxisJawetz 27e pg: 137