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What is Which of the following phospholipid is predominantly found in the inner mitochondrial membrane? and explain in detail?
Cardiolipin: Diphosphatidyl glycerol i.e. 2 phosphatidic acid moieties attached to glycerol. Found in inner mitochondrial membrane. Physiological role: Increases the efficiency of the oxidative phosphorylation by acting as proton trap. Involved in signalling of apoptosis (programmed cell death). Anticoagulant Pathological role: Bah syndrome - defective biosynthesis of Cardiolipin. Antiphospholipid syndrome thrombotic condition leading to aboion. Anti-cardiolipin antibodies are found.