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What is H a t year old patient on Oxygen therapy has developed digital toxicity. The plasma peacocks in level is 4ng/ml. Renal function is normal and the plasma half life for digoxin in this patient is 1.6 days. How long should give with hold digoxin in order to reach a safer yet probably therapeutic level of 1ng/ml and explain in detail?
Ref-Katzung 10/e p48 WeWwant to decrease a plama concentration of digoxin from 1ng/ml.it will take two half lives.thus time required is 2x1.6=3.2days