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What is Human papilloma virus-8 infection is associated with: March 2012 and explain in detail?
Ans: D i.e. Flat was HPV infection Anogenital was are caused predominantly by HPV types 6 and 11 In 1994, a previously unrecognized herpes virus-human herpesvirus-8 (HHV-8) or Kaposi Sarcoma/ KS associated herpes virus (KSHV) was identified in a cutaneous KS lesion in an AIDS patients. Indeed, regardless of the clinical subtype, 95% of the lesions have subsequently been shown to be KSHV infected HPV type 16 has also been associated with in situ squamous cell carcinoma of the genitalia and with bowenoid papulosis The relationship of HPV 5 and 8 to squamous cell carcinomas, paicularly in individuals affected by the rare condition, epidermodysplasia verruciformis is well known. These patients develop multiple flat was that contain HPV genomes, some of which progress to carcinoma