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What is Normal adult GFR is and explain in detail?
(120-130 ml/min, 1.73 msq/cm2) (706-GN) (646- Ganong 23rd)* The GFR in an average-sized normal man is approximately 125 mL/min. Its magnitude correlates fairly well with surface area, but values in woman are 10% lower than those in men even after correction for surface area.Factors that can decrease the GFR (288-Gyton 10th)Physiologic/ Pathophysiologic causes* Renal disease, DM, hypertension* Urinary tract obstruction (eg. Kidney stones)* | Renal blood flow, increased plasma proteins* | Arterial pressure (has only small effect due to autoregulation)* | Angiotensin II (drugs that block angiotensin II formation)* | Sympathetic activity, vasoconstriction hormones (eg. Norepinephrine, endothelin)