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What is Xanthogranulomatous pyelonephritis is most often due to and explain in detail?
Xanthogranulomatous pyelonephritis occurs when a chronic urinary obstruction (often by staghorn calculi), together with chronic infection, leads to the suppurative destruction of renal tissue.Proteus infection is associated with staghorn formation.Ref: Harrison; 19th edition; Page no: 1033