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What is Which of the following is not a malabsorption syndrome? and explain in detail?
Tangier's disease is an autosomal recessive disorder caused by mutations in the ATP binding cassette transpoer 1(ABC1) gene.It is characterized by multiple mononeuropathies, polyneuropathy or pseudo-syringomyelia pattern with yellowish orange tonsils, lymphadenopathy, splenomegaly may also be present.There will be markedly reduced levels of HDL and increased levels of triacylglycerol.There are many causes of malabsorption. Some specific disease entities are celiac disease, tropical sprue, Whipple's disease, Bacterial overgrowth syndrome, Sho bowel syndrome, Protein-losing enteropathy.Ref: Harrison 18/e p2475, 3456.