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What is Ursodeoxycholic acid is a and explain in detail?
Medical therapy of Gallstones Medical therapy of gallstones utilize bile acids : Chenodeoxycholic acid(CDCA) and Ursodeoxycholic acid(UDCA) Mechanism of Action : They inhibit HMG-CoA reductase, rate limiting enzyme for cholesterol synthesis, thus decreasing cholesterol saturation of bile They cause disruption of cholesterol from the stones by physicochemical means Ref: Sabiston 20th edition Pgno : 1494