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What is Triad of hairy cell leukemia includes all Except and explain in detail?
Hairy Cell Leukemia: This is rare but distinctive B-cell neoplasm constitutes about 2% of all leukemias. Clinical manifestations result largely from infiltration of the bone marrow, liver, and spleen. Splenomegaly, often massive, is the most common and sometimes the only abnormal physical finding. Hepatomegaly is less common and not as marked; lymphadenopathy is rare. Pancytopenia resulting from marrow involvement and splenic sequestration is seen in more than half the cases. About one-third of those affected present with infections. There is an increased incidence of atypical mycobacterial infections, possibly related to frequent unexplained monocytopenia. Reference: Robbins and Cotran Pathologic Basis of Disease; 9th edition; Chapter 13; Diseases of White Blood Cells, Lymph Nodes, Spleen, and Thymus