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What is AIDS involves: and explain in detail?
Ans. is 'a' i.e., Helper T Cells (Ref: Ananthanarayan, 9th/e, p. 574, and 8th/e, p. 572)The receptor for the virus is the CD4 antigen on surface. The cells affected are:- CD4 T Cells (major target).- B lymphocytes.- Monocytes and macrophages.- Langerhans cells in dermis.- Glial cells and microglia in the CNS.- Follicular dendritic cells from tonsils can be infected by HIV without the involvement of CD4.