You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which of the following represents an example of metastatic calcification? and explain in detail?
End-stage renal failure leads to hyperparathyroidism and secondarily to hypercalcemia. The latter results in metastatic calcification. Old foci of tuberculosis, a calcified mitral valve damaged previously by rheumatic fever, and calcification within breast cancer are all examples of dystrophic calcification.