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What is In the investigation of a patient with suspected essential thrombocythaemia, in which of the following genes may you find abnormalities? and explain in detail?
All of these mutated genes are associated with haematological conditions : BCR with chronic myeloid leukaemia (CML), c-MYC and BCL-2 with lymphoma, and MYH-9 with congenital thrombocytopathy. Only CAL-R, calreticulin, is associated with the myeloproliferative neoplasm essential thrombocythaemia.