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What is The unique propey of SERMs is that they: and explain in detail?
SERM: 1. Raloxifene- Agonist at bone - Agonist in blood : Increase HDL level- Antagonist at breast: Decrease breast carcinoma risk- Antagonist at endometrium: Decrease endometrium carcinoma- Agonist at liver: Increase thromboembolism risk 2. Tamoxifen- Agonist at bone - Agonist in blood : Increase HDL level- Antagonist at breast: Decrease breast carcinoma risk- Agonist at endometrium: Increase endometrium carcinoma- Agonist at liver: Increase thromboembolism risk Tamoxifen, Doloxifen and toremifene are beneficial on: - Bone - Blood - Breast 3. Clomifene Antagonist at pituataryHypothalamus - GnRHPituatary - LH/FSHOvary - E/P