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What is Apoptosis is inhibited by? and explain in detail?
Ans. (a) Bcl-2Ref: Robbing pathology 9th ed. /53-54* Apoptosis is inhibited by anti-apoptosis genes which are mostly BCL family genes.# Example: BCL2, BCL-X, BCL-XL* Pro-apoptotic genes: they initiate and are involved in apoptosis.# Example: BAD, BIM, BAX, BAK* P53 is tumor suppressor gene and it causes apoptosis when there is excess of DNA damage which cannot be repaired