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What is Large giant cells are found in - and explain in detail?
Ans. (b) Neonatal hepatitis(Ref: Robbins 9th/pg 857)The morphologic features of neonatal hepatitis include:Lobular disarray with focal liver cell apoptosis and necrosis QPanlobular giant-cell transformation of hepatocytes QProminent hepatocellular and canalicular cholestasisMild mononuclear infiltration of the portal areas,Reactive changes in Kupffer cellsExtramedullary hematopoiesis