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What is Calabar swelling is due to - and explain in detail?
Ans. is 'a' i.e., Hypersensitivity to adult worm of Loa-Loa [Ref: Chatterjee 12thIe p. 202}Loiasis* Loiasis is caused by L. Loa (the African eye worm)* Habitat of adult worms is subcutaneous connective tissue of man; often in the sub-conjuctival tissue of the eye.* The worm passes its life cycle in two hosts :# Man# Chrysops (Mango or deer flies)* It causes a characteristic subcutaneous swelling called Calabar (fugitive) swelling. It is due to hypersensitivity reaction to adult worm.