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What is HER-2/ neu receptor play a role in: and explain in detail?
Ans. is 'a' i.e., Predicting therapeutic response o Overexpression of HER-2/neu in breast cancer patients is associated with poor prognosis and increases disease recurrence. o Overexpression HER-2/neu also predicts good response to transtuzumab (Herceptin), a drug approved for HER-2/ neu overexpressing breast cancer. o Because of its prognostic role as well its ability to predict response to transtuzumab (Herceptin), breast cancers are routinely checked for overexpression of HER-2/neu.