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What is Most commonly used route of administration of heparin for post-operative thromboprophylaxis is? and explain in detail?
UFH is injected s.c. every 8- 12 hours, staed before surgery and continued for 7-10 day, or till the patient stas moving about. This regimen has been found to prevent postoperative deep vein thrombosis (post operative thromboprophylaxis) without increasing surgical bleeding. It also does not prolong aPTT or clotting time. However, it should not he used in case of neurosurgery or when spinal anaesthesia is to be given.