You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Treatment of lithium Induced diabetes Insipidus - and explain in detail?
Ans is option 3- amiloride Amiloride is currently the treatment of choice for polyuria in lithium induced diabetic insipidus. Amiloride a potassium sparing diuretic is the drug and raise maximum urinary osmolality in lithium treated patients. It blocks the cellular uptake of lithium ENaC. Thus antogonizing the inhibitory effects of lithium on Vasopressin induced water transpo. Ref Harrison 19 /304