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What is Regarding sulpha group of drugs all the below statements are true, except: and explain in detail?
Sulfasalazine is usaually absorbed from the small intestines. Only 10% of drug is absorbed remaining excreted unaltered in bowel. Hence, this drug acts locally in the intestine of patient with inflammatory bowel disease. Ref: Paul Beringer (2006), Chapter 90, "Antiinfectives", In the book, "Remington: The Science and Practice of Pharmacy", Lippincott Williams and Wilkins, USA, Page 1631 ; KD Tripathi, 5th Edition, Pages 186, 643 ; Katzung 9th Edition, Page 591