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What is Paget's disease of breast is a manifestation of and explain in detail?
Ans. (a) Ductal carcinoma(Ref Bailey and Love 27th edition Page 873)* Paget's disease of nipple is the manifestation of underlying Ductal carcinoma, Nipple gets eroded completely and disappears.* Large ovoid cells with abundant Pale staining cytoplasm in malphigian layer of skin is Paget's cells