You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Placental ALP is used as tumor marker of and explain in detail?
Ans a: (Ref: Robbins 7th edition 1041-42)Testicular tumorsTumor markers1 SeminomaPlacental ALP2 Embryonal carcinomahC'GAFP3 Yolk sac tumor (endodermal sinus tumor)AFP, Alpha 1 AT4 ChoriocarcinomahCGSeminomaMost common type germ cell tumor of testis(50%)Female counterpart is dysgerminoma. Tumor is positive for placental ALP & negative for AFP.Spermocytic seminoma is a morphologic variant that tend to occur in old people.