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What is In the management of symptomatic Benign Prostatic Hyperplasia with finasteride the period of trial required for determining a satisfactory response is and explain in detail?
Finasteride is 5-alpha reductase inhibitor which inhibits conversion of testosterone to dihydrotestosterone. It is effective in palpably enlarged prostate(>50g). 5mg is used daily for at least 6 months for satisfactory response. It has fewer side effects. It is contraindicated in obstructive uropathy or carcinoma prostate.Reference : page 1047 SRB&;s manual of surgery 5th edition and page 1350 Bailey and Love&;s sho practice of surgery 25th edition