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What is Proinflammatory cytokines include all of the following except and explain in detail?
ref Robbins 8/e p56 ; cytokines and pain p3,9/e p86 the following are anti inflammatory cytokines-IL10,TGF-beta,IL _13 An inflammatory cytokine or proinflammatory cytokine is a type of signaling molecule (a cytokine) that is excreted from immune cells like helper T cells(Th) and macrophages, and ceain other cell types that promote inflammation. They include interleukin-1(IL-1), IL-12, and IL-18, tumor necrosis factor alpha(TNF-a), interferon gamma (IFNg), and granulocyte-macrophage colony stimulating factor (GM-CSF) and play an impoant role in mediating the innate immune response. Inflammatory cytokines are predominantly produced by and involved in the upregulation of inflammatory reactions.