You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Th 1 type of cells are most dependent on - and explain in detail?
Ananthanarayanan and Paniker's textbook of microbiology 9th edition . TH1 cells which produce cytokines , INF Gamma and IL2, which activate macrophage and T cells promoting cell mediated immunity, destruction of the target cells and killing of intracellular pathogens. .