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What is Defence mechanism by the bacteria which produce biofilm are all except? and explain in detail?
Biofilms: These are well-organised microcolonies of bacteria enclosed in self-produced extracellular polymer matrices known as glycocalyx. They are separated by water channels that remove water and deliver nutrients. Biofilm is one of the mechanisms of antibiotic resistance. They stick to the surface strongly. Antibiotics penetration into the biofilm is less. They protect from the inflammatory mediators. Efflux pumps- Expulsion of the drug from the cell soon after their entry to prevent intracellular accumulation of the drug.