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What is Mechanism of action of Levetiracetam are all except and explain in detail?
(C) Inhibits post synaptic calcium channels# Mechanism of Action:> Inhibits a specific high-voltage activated calcium channel, the N-type> Inhibit the release of calcium from intracellular stores.> Oppose the inhibitory action of zinc and beta-carbolines on GABA- and glycine-gated currents. Inhibits burst firing without affecting normal neuronal excitability.> Hypersynchronization of epileptiform activity is inhibited, and its distinguished Levetiracetam from other AEDs.> Saturable and reversible stereoselective binding site specific for levetiracetam in CNS, SV2A.> Exact mechanism by which levetiracetam acts to treat epilepsy is unknown However, the drug binds to a synaptic vesicle glycoprotein, SV2A, and inhibits presynaptic calcium channels reducing neurotransmitter release and acting as a neuromodulator.> Levetiracetam: Binds to a synaptic vesicle glycoprotein (involved in the regulation of vesicle exocytosis), SV2A, & inhibits presynaptic calcium channels reducing neurotransmitter release & acts as a neuromodulator. Levetiracetam is an anticonvulsant used to treat epilepsy. Levetiracetam may selectively prevent hypersynchronization of epileptiform burst firing and propagation of seizure activity.