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What is All of the following are autoimmune diseases, EXCEPT: and explain in detail?
Sickle cell diease is not an autoimmune disease. Sickle Cell Disease is a structural hemoglobinopathy caused by a mutation in the f3-globin gene that changes the sixth ammoacid from glutamic acid to valine (HBS a2 B2 6Glu?Val), The mode of inheritance is autosomal recessive. Ref: Harrison 16th Edition, Page 678 ; Robbins Pathologic basis of disease 6th Edition, Page 611.