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What is Immuno-proliferative lymphoma presents with? and explain in detail?
Immunoproliferative small intestinal disease (IPSID), is a B cell tumor. The presentation includes chronic diarrhoea, steatorrhea associated with vomiting and abdominal cramps. IPSID presents with intestinal secretions of an abnormal IgA that contains a shoened heavy chain and is devoid of light chains. It is suspected that the abnormal chains are produced by plasma cells infiltrating the small bowel. The clinical course is one of exacerbations and remissions, with death due to malnutrition and wasting or the development of a lymphoma.