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What is Digoxin is contraindicated in - and explain in detail?
Ans. is 'd' i.e., Hyperophic obstructive cardiomyopathy Digitalis is contraindicated in o HOCM - By increasing the contractility it decreases the size of ventricle --> obstruction. o Paia1A-V block - Digitalis increases ERP of A-V node --> A.V. conduction --> may conve paial block into complete block. o WPW syndrome - Digitalis slows the conduction in the normal AV bundle and accelerates it in the aberrant pathway --> increase chances of reentry --> ventricular fibrillation may occur. o Ventricular tachycardia - Digitalis decreases the refractory period of ventricle muscle ventricular fibrillation may occur.