You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which is not a feature of neoplastic cell? and explain in detail?
Ans: d (Nuclear cytoplasmic ratio 1:4)The hallmark of malignant transformation is anaplasia.The morphological changes in anaplasia are:-1) Pleomorphism: by both cell & nuclei2) Abnormal nuclear morphology: HyperchromasiaNuclear cytoplasmic ratio approaches 1:1 (normal is 1:4 or 1:6)Large nucleoli3) Large no of mitoses4) Loss of polarity5) Other changes: tumour giant cells