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What is Which Anti glaucoma drug can induce pigmentation of iris? and explain in detail?
Ans. C. LatanoprostPGF2 analogsa. Latanoprost, bimatoprost, travoprost and unoprostoneb. Lower IOP by increasing aqueous outflow through uveo-scleral outflow pathway. Bimatoprost also increases trabecular outflowc. 1st line drugs due to their once-daily dosing, low incidence of systemic side effects, and potent IOP lowering effectd. Side effects (CLIP-D)e. C- Cystoid macular edema (more common in aphakic individuals)f. L-lengthening of eye lashesg. I - Inflammatory condition of eye like Uveitis, Keratitis, conjunctivitis can be worsenedh. P - pigmentation (brownish) of iris and lower eye lids (heterochromia iridis)i. D-Deepening of upper eyelid sulcus