You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Commonest site of bone involvement in hematogenous osteomyelitis: and explain in detail?
Ans is 'a' i.e. Metaphysis Repeat from May 09Acute osteomyelitis is almost invariably a disease of children. When adults are affected it may be because their resistance is lowered by debility, disease or drugs.Acute osteomyelitis may result from hematogenous spread of the infecting organism, or may be infected secondarily from the spread of a contiguous area of infection, or direct inoculation of bacteria in the bone (open fractures, nail punctures of the foot).Hematogenous spread is the commonest means of production of osteomyelitis.Commonest site is metaphysis. This is because of the peculiar arrangement of the blood vessels in that area, which leads to relative vascular stasis, favouring bacterial colonization. - Commonest site: Lower femoral metaphyses > Upper tibial, upper femoral, upper humeral metaphyses.Acute hematogenous osteomyelitis behaves differently in neonates from the way it does in children. Because blood vessels cross the growth plate in neonates and infants younger than age 18 months, the bone infection that develops in that age group will likely cross the physis; however, in older children, acute infections rarely cross the growth plate.In adults, hematogenous infection is more common in the vertebrae than in the long bones.