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What is True statement about pulmonary embolism and explain in detail?
Unfractionated Heparin UFH anticoagulates by binding to and accelerating the activity of antithrombin, thus preventing additional thrombus formation. UFH is dosed to achieve a target activated paial thromboplastin time (aPTT) of 60-80 s. The two principal indications for inseion of an IVC filter are (1) active bleeding that precludes anticoagulation and (2) recurrent venous thrombosis despite intensive anticoagulation. Ref Davidson edition23rd pg 620