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What is In which of the following age group myelodysplastic syndrmome (MDS) are most common: and explain in detail?
Answer is D (> 50 years) Idiopathic MDS is a disease of the elderly. The mean age of onset is 68 years. Myelodysplastic Syndromes (Disease of the elderly with mean onset > 68 years) Heterogenous group of haematological disorder Characterized by - Peripheral blood cytopenias - Trilineage dysplastic changes - Hypercellular bone marrow - Propensity to undergo transformation into Acute Myeloid LeukaemiaQ. The French American British Group has classified this disorder into 5 pathological entities - Refractory Anemia - Refractory Anemia with ring sideroblasts - Refractory Anemia with Excess blasts - Refractory Anemia with Excess blasts in transformation - Chronic Myelomonocytic Leukaemia