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What is Which of these is true of E. Coli and explain in detail?
Heat-labile toxin of E.coli acts similar to Cholera toxin as it binds to GM1 ganglioside receptors on intestinal epithelial cells by means of subunit B, following which subunit A is activated to yield two fragments: A1 and A2. The A1 fragment activates adenyl cyclase in the enterocyte to form CAMP, leading to an increased outflow of water and electrolytes into the gut lumen, with consequent watery diarrhea. Reference: Textbook of Microbiology; Anathanarayan and paniker's; 10th edition; Page no: 282