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What is Which of the following statements about fibromyalgia is true: and explain in detail?
Pathogenetic features in fibromyalgia:Disruption of normal stage IV NREM sleepLow levels of serotonin metabolites in CSFReduced levels of growth hormoneIncreased levels of neurotransmitter substance P in CSFDecreased coisol response to stress and coicotrophin-releasing hormoneAutonomic dysfunctionReduced blood flow to the thalamus, caudate nucleus, and tectum on SPECTPsychiatric disturbances(ref:Harrison's 18/e p2849-2851, 17/e p2180)