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What is platelet activating factor causes all except: and explain in detail?
PAF is another phospholipid derived mediator having the following inflammatory effects: Platelet aggregation Vasoconstriction Bronchoconstriction At extremely low concentration, it may cause vasodilation and increased venular permeability Increases leukocyte adhesion to the endothelium (by enhancing integrin-mediated leukocyte binding), chemotaxis, degranulation, and the oxidative burst. Stimulates the synthesis of other mediators, paicularly eicosanoids, by leukocytes and other cells. ref robbins 9/e page 89