You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is On increasing vagal tone following occurs in pacemaker and explain in detail?
When the cholinergic vagal fibers to nodal tissue are stimulated, the membrane becomes hyperpolarizedThe slope of the prepotentials is decreased because the acetylcholine released at the nerve endings increases the K+ conductance of nodal tissue.Which cause rapid efflux of K+Ref: Ganong's Review of Medical Physiology Twenty-Third Edition Page No: 491