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What is Tangier disease is due to deficiency of and explain in detail?
Name Defect Remarks Familial alpha-lipoprotein deficiency Tangier disease Fish-eye disease apo-A-I deficiencies All have low or near absence of HDL Tendency toward hyperiacylglycerolemia as a result of absence of apo C-ll, causing inactive LPL. Low LDL levels. Atherosclerosis in the elderly. Reference: Harper; 30th edition; Page no: 275