You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is DNA analysis of chorionic villus/amniocentesis is not likely to detect : and explain in detail?
Ans. is a i.e. Tay sachs disease In chorionic villous biopsy, trophoblastic tissue is obtained from the chorionic villi. followed by biochemical or molecular (DNA) analysis of this tissue to diagnose various conditions. Diagnostic chorionic villous biopsy Conditions which require molecular or DNA analysis Conditions which require biochemical analysis Hemoglobinopathies tsickle cell disease) * Tay Sacn s disease Cystic fibrosis * Neimen pick disease Duchenne's or Berkers muscular dystrophy * Gaucher's disease Hemophilia A & B * Urea cycle defects Down syndrome * Amino acid disorder Congenital adrenal hyperplasia * Congenital adrenal hyperplasia Thus for diagnosis of Tay Sach's disease biochemical analysis of chorionic villous sample is done (not DNA analysis). Note : Congenital adrenal hyperplasia can be diagnosed both by biochemical testing and DNA analysis.