You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Reverse transcriptase is a RNA dependent DNA polymerase. Which of these use it? and explain in detail?
Ans. (b) Hepatitis B virus Set ot te,, DNA polymerase of HBV has both DNA-dependent DNA polymerase and RNA-dependent reverse transcriptase activities. Not Instead of DNA replication directly from a DNA template, hepadnaviruses rely on reverse transcription (effected by the DNA polymerase) of minus-strand DNA from a "pregenomic" RNA intermediate. Then plus-strand DNA is transcribed from the minus strand DNA template by the DNA-dependent DNA polymerase and conveed in the hepatocyte nucleus to a covalently closed circular DNA, which serves as a template for messenger RNA and pregenomic RNA.