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What is True about RIBOZYME: (AIIMS November 2013, November 20/3) and explain in detail?
Ans. a. Peptidyl transferase activity (Ref: Harper 28/e p364; 27/e p364; Lippincott 4/e p435-439; Lehninger 5/e p1078)Ribozymes are RNA molecule with catalytic activityQ. Ribozymes play a central role in peptide bond formation (peptidyl transferase activity).RibozymeRibozymes are RNA molecule with catalytic activityQ.These generally involve transesterification reactions, and most are concerned with RNA metabolism (splicing and endoribonuclease).Recently, a ribosomal RNA component was noted to hydrolyze an aminoacyl ester and thus play a central role in peptide bond formation (peptidyl transferase) Q.