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What is Which of the following is FDA approved Anti-CTLA-4 immunotherapy agent for the treatment of metastatic melanoma? and explain in detail?
TREATMENT OPTIONS FOR METASTATIC MELANOMA - Surgery: Metastasectomy for small number of lesions Immunotherapy: - Interleukin-2 - Immune checkpoint blockade FDA approved - Anti-CTLA-4: Ipilimumab Experimental - Anti-PD-1: Nivolumab, Lambrolizumab (Monoclonal antibody to programmed cell death-1 protein (PD-1); blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2 Molecular targeted therapy: - BRAF inhibitor: Vemurafenib, Dabrafenib - MEK inhibitor: Trametinib