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What is First purine nucleotide, which is synthesized in purine biosynthesis ? and explain in detail?
The biosynthesis of purine begins with ribose-5-phosphate, derived from pentose phosphate pathway (PPP). First intermediate formed in this pathway, 5-phosphoribosyl-pyrophosphate (PRPP), is also an intermediate in purine salvage pathway. REF: Lippincott book of biochemistry 6th ed.