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What is Coombs positive hemolytic anemia associated with: and explain in detail?
Answer is C (SLE) Coombs positive hemolytic anemia is a feature of autoimmune hemolytic anemia and is characteristically seen in SLE. Polvaeritis Nodosa (PAN) may also be associated with a Coombs positive hemolytic anemia. However this association is rare, and more commonly patients with PAN present either with an anemia of chronic disease or a microangiopathic hemolytic anemia. TTP and HUS are characteristically associated with Coombs negative microangiopathic hemolytic anemias.