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What is The most common complication associated with 'Total Parenteral Nutrition' is and explain in detail?
The most common complication associated with TPN is a Catheter-related infectionTotal parenteral nutrition (TPN) is defined as the provision of all nutritional requirements by means of the intravenous route and without the use of the gastrointestinal tract.Parenteral nutrition is indicated when energy and protein needs cannot be met by the enteral administration of these substrates. The most frequent clinical indications relate to those patients who have undergone massive resection of the small intestine, who have an intestinal fistula or who have prolonged intestinal failure for other reasons.TPN can be administered either by a catheter inseed in the central vein or peripherally inseed central venous catheter (PICC) line or a conventional cannula (not preferred).Catheter-related sepsis occurs in 3-14% of patients. It may occur at the time of line inseion or afterwards by migration of skin bacteria along the external catheter surface.