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What is Risperidone increases the risk of: and explain in detail?
Risperidone Another compound whose antipsychotic activity has been ascribed to a combination of D2 + 5-HT 2 receptor blockade. In addition it has high affinity for a11 a2 and H1 receptors: blockade of these may contribute to efficacy as well as side effects like postural hypotension. However, BP can rise if it is used with selective serotonin reuptake inhibitors. Risperidone is more potent D2 blocker than clozapine; extrapyramidal side effects are less only at low doses ( <6 mg/ day). Prolactin levels rise during risperidone therapy, but it is less epileptogenic than clozapine, though frequently causes agitation. Caution has been issued about increased risk of stroke in the elderly. Ref KD Tripati 8th ed.