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What is Superantigen includes all, Except and explain in detail?
Superantigens are ceain protein molecules that activate very large number of T cells irrespective of antigenic specificities They bind directly to the lateral aspect of TCR b chain and activate upto 20% of the circulating T cells compared to conventional (0.001%) causing multisystem dysfunction.Examples :Toxic shock syndrome toxinExfoliative toxinStaphylococcal anterotoxinPyrogenic exotoxin