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What is Carvedilol is an effective antihypeensive agent that, like propranolol, is capable of blocking beta receptors. An impoant difference between the two drugs is that carvedilol and explain in detail?
a + b ADRENERGIC BLOCKERS Includes Labetalol, Carvedilol. Carvedilol:- It is a b1 + b2 + a1 adrenoceptor blocker; produces vasodilatation due to a1 blockade as well as calcium channel blockade, and has antioxidant propey. It has been used in hypeension and is the b blocker especially employed as cardioprotective in CHF. Oral bioavailability of carvedilol is 30%. It is primarily metabolized and has a t 1/2 of 6-8 hrs. Ref:- kd tripathi; pg num:-151