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What is Doxycycline is used in the treatment of following disease except: and explain in detail?
TETRACYCLINES These are a class of antibiotics having a nucleus of four cyclic rings. The tetracyclines still available in India for clinical use are: Tetracycline Oxytetracycline Demeclocycline Doxycycline Minocycline Uses: Although tetracyclines are broad-spectrum antibiotics, they should be employed only for those infections for which a more selective and less toxic AMA is not available. Clinical use of tetracyclines has very much declined due to availability of fluoroquinolones and other efficacious AMAs. USES: >Mild leptospirosis is treated with doxycycline, ampicillin, or amoxicillin. For severe leptospirosis, intravenous penicillin G has long been the drug of choice, although the third-generation cephalosporins cefotaxime and ceftriaxone have become widely used. >Rickettsial infections: typhus, rocky mountain spotted fever, Q fever, etc. respond dramatically. Chloramphenicol is an alternative. >Relapsing fever* due to Borrelia recurrentis responds adequately ESSENTIALS OF MEDICAL PHARMACOLOGY, www.medscape.com K.D.TRIPATHI SIXTH EDITION PAGE NO:715