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What is Drug which doesn't inhibit nucleic acid synthesis? and explain in detail?
Ans. D. Linezolida. Linezolid - Inhibits protein synthesis via binding to 50s subunit on ribosomes.b. Inhibition of Nucleic Acid Synthesis:c. Rifamycins- Inhibit bacterial RNA polymerased. Fluoroquinolones- Inhibit enzymes (DNA Gyrase) that are required for bacterial DNA synthesise. Nitrofurantoin- Generates metabolites that are incorporated into DNA strands, making more prone to breakage