You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is What is mechanism of action of curonium drugs as muscle relaxant? and explain in detail?
Persistently depolarizing at neuromuscular junction - propey of succinylcholine depolarising eg : succinylcholine 1. MOA - persistent / prolonged depolarising of nicotinic cholinergic receptors 2. fasiculation seen 3. post operative myalgia 4. not reversed by neostigmine 5. train of four response not seen 6. TOF ratio (B/A = 1 ) 7. neuromuscular monitoring not done 8. no post tetanic facilitation non - depolarising 1. MOA - competitive antagonist 2. fasiculation not seen 3. no post operative myalgia 4. reversed by neostigmine 5. train of four response seen 6. TOF ratio (B/A< 1 ) 7. neuromuscular monitoring done 8. post tetanic facilitation seen