You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is At the physiological pH the DNA molecules are: and explain in detail?
DNA molecules are negatively charged. Histones, along with positively charged ions such as Mg2+, help neutralize the negatively charged DNA phosphate groups. Histone proteins possess an unusually high content of basic amino acids (arginine and lysine) that, through ionic bonds, facilitate interaction with the negatively charged DNA. Ref: Biochemistry By Richard A. Harvey (Ph. D.), Richard A. Harvey, Denise R. Ferrier, 2011, Page 409.