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What is An 8-month-old boy baby is evaluated because of repeated episodes of pneumococcal pneumoniA Serum studies demonstrate very low levels of IgM, IgG, and IgA This patient's condition is related to a deficiency of which of the following proteins? and explain in detail?
As the history is of recurrent infections with bacteria (pneumococcal pneumonia), it indicates primary humoral immunodeficiency. As this is occurring in a 8-month old male child, it indicates X-linked agammaglobulinaemia also called as buon's agammaglobulinaemia. In this disorder there is deficiency of the enzyme tyrosine kinase, which is required for B cell maturation