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What is False about Randomised Control Trials is and explain in detail?
The essential purposes of randomization in a randomized controlled trial are:
- Participants have ‘Equal and Known Chance’ of falling into either ‘Experimental Group’ or ‘Reference Group’
- To eliminate Selection Bias (Selection Bias or ‘Susceptibility Bias’ is the bias due to differential susceptibility of two groups to outcome, even before intervention/experiment is performed; Thus two groups are not comparable)
- To ensure comparability among two groups
- To have ‘similar prognostic factors’ among two groups
- ‘Randomisation is done while dividing patients into the Experimental (Intervention) Group and the Reference Group’ AND not while selecting patients for RCT
- Randomisation is known as ‘Heart of a trial’
- Randomisation is superior to Matching.