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What is Which of the following anti TB drugs acts on extracellular organisms and is bactericidal drug? and explain in detail?
Streptomycin is the only anti-TB drug which acts on extracellular organisms and is bactericidal. All first line antitubercular drugs are bactericidal except ethambutol which is bacteriostatic. Impoant points about first line ATT: Drug Action Hepatotoxic Bacteria Inhibited Isoniazid CIDAL Yes Both Rifampicin CIDAL Yes Both Pyrazinamide CIDAL Yes Intracellular Ethambutol STATIC No Both Streptomycin CIDAL No Extracellular