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What is Amino acid which is usehil in Neutrophil extracellular traps (NETs) as to causes lysis of chromatin is? and explain in detail?
Ans. (a) Arginine(Ref: R 9th/pg 81)NETs contain a framework of nuclear chromatin with embedded granule proteins, such as antimicrobial peptides and enzymes. The nuclear chromatin in the NETs, includes histones and associated DNA. Histone modification by peptidylarginine deiminase 4 (PAD4) is necessary for NET release.