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What is Cerebral malaria is most commonly associated with which of the following? and explain in detail?
Appropriately and promptly treated, uncomplicated falciparum malaria (i.e., the patient can swallow medicines and food) carries a moality rate of 0.1%. However, once vital-organ dysfunction occurs or the total propoion of erythrocytes infected increases to >2% (a level corresponding to >1012 parasites in an adult), moality risk rises steeply. Cerebral Malaria : Coma is a characteristic and ominous feature of falciparum malaria and, despite treatment, is associated with death rates of 20% among adults and 15% among children. Any obtundation, delirium, or abnormal behavior should be taken very seriously. The onset may be gradual or sudden following a convulsion. Ref: White N.J., Breman J.G., Osler W. (2012). Chapter 210. Malaria. In D.L. Longo, A.S. Fauci, D.L. Kasper, S.L. Hauser, J.L. Jameson, J. Loscalzo (Eds), Harrison's Principles of Internal Medicine, 18e.