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What is Richter transformation is conversion of? and explain in detail?
MC B cell NHL : DLBCL CLL/SLL (Small lymphocytic lymphoma) | Richter transformation DLBCL (Diffuse lager B cell Lymphoma) Clinical signs of Richter's transformation include rapid progression in lymphadenopathy and constitutional symptoms including fatigue, night sweats, fever, and weight loss. LDH is usually high. Therapy for DLBCL Richter's transformation usually involves combination chemoimmunotherapy.