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What is A 28 year old female patient who is a lactating mother and has a history of hepatectomy reported for follow up. Which of the following cellular adaptations will be seen in this patient? and explain in detail?
Hypertrophy:-
→ Increase in size and functions of cells.
→ Results due to increase in growth factor or trophic stimuli.
→ Includes puberty, lactating breasts and skeletal muscle fibers (in bodybuilders).
Hyperplasia:-
→ Increase in number of cells (in tissue) organ.
→ Results due to increase in growth factors, increased expression of growth-promoting genes and increased DNA synthesis.
→ It persists as long as stimulus is present.
Eg:- Breast development at puberty, endometrial hyperplasia, benign hyperplasia of prostate, hypertrophy of liver cells after partial hepatectomy.