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What is Most common drug induced skin reaction: and explain in detail?
Ans. b (Morbilliform rash). (Ref Harrison's medicine 18,h/ch. 55)DRUG-INDUCED SKIN REACTIONSMaculopapular eruptions are seen in the classic childhood viral exanthems, including:1)rubeola (measles)a prodrome of Coryza, Cough, and Conjunctivitis followed by Koplik's spots on the buccal mucosa; the eruption begins behind the ears, at the hairline, and on the forehead and then spreads down the body, often becoming confluent;2)rubellathe eruption begins on the forehead and face and then spreads down the body; it resolves in the same order and is associated with retroauricular and suboccipital lymphadenopathy; and3)erythema infectiosum (fifth disease)erythema of the cheeks ("Slapped-cheek" appearance) is followed by a reticulated pattern on extremities; it is secondary to a parvovirus B19 infection, and an associated arthritis is seen in adults.