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What is Von Magnus phenomenon? and explain in detail?
When passaged serially in eggs,using as inocula undiluted infected allantoic fluid,the progeny virus will show high hemagglutinin titres ,but low infectivity. This has been called the Von Magnus Phenomenon and is due to the formation of incomplete virus paicles lacking nucleic acid. REF:ANANTHANARAYAN AND PANIKER'S TEXTBOOK OF MICROBIOLOGY 9TH EDITION PAGE NO.500