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What is A ten-year old girl presents with swelling of one knee joint. All of the following conditions can be considered in the differential diagnosis, EXCEPT: and explain in detail?
Hemophilia is an X-linked recessive hemorrhagic disease due to mutation in the F8 gene (Hemophilia A or Classic Hemophilia) or F9 gene (Hemophilia B). Males subjects are clinically affected; women who carry single mutated gene are generally asymptomatic. Ref: Kliegman, Behrman, Jenson, Stanton (2008), Chapter 476, "Hereditary Clotting Factor Deficiencies", In the book, "NELSON TEXTBOOK OF PEDIATRICS", Volume 2, 18th Edition, New Delhi, Page 2066; Harrison's Internal Medicine, 19th Edition, Page 975.