You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is The following statement about this condition is true: and explain in detail?
The given condition is keloid. Keloid- Has Excessive scar tissue- Scar extends beyond the boundaries of original wound or incision - Etiology - Unknown- Associated with* Elevated levels of growth factors* Deeply pigmented skin* Genetic predisposition* Areas of body where there is increased risk of keloid formation- Above clavicle- Upper extremities- Trunk & Face- Especially seen in the Triangular region with boundaries of Each shouldertip and Xiphisternum - On Histology* Excess collagen & Hypervascularity* Contains disorganized Type I & III collagen* Contains thicker collagen bundles - causes formation of acellular node like structures* Rarely regresses with time* Often refractory to Medical & Surgical intervention - Treatment* First line treatment - Silicones + Pressure therapy + Intralesional injection of triamcinolone * In Refractory Cases (No improvement after 12 months of treatment) - Excision + Post-operative Radiotherapy (External beam radiotherapy / Brachytherapy)