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What is A 3-month old male child with normal genitalia presents to the emergency depament with severe dehydration, hyperkalemia and hyponatremia. The measurement blood levels of which of the following will be helpful ? and explain in detail?
Ans. is 'a' i.e., 17 hydroxyprogesterone o This is a case of congenital adrenal hyperplasia due to deficiency of 21 - hydroxylase deficiency. o Because of the enzyme block ,there is increased formation of 17- hydroxyprogesterone, which is then shunted into the production of testosterone. o Levels of coisol and aldosterone are reduced.