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What is Wrong about clonidine is ? and explain in detail?
Ans. is 'b' i.e., First line for ADHD o Behavioural therapy is the first line therapy for the treatment of ADHD. The first line drug for ADHD is Methylphenidate. Clonidine It acts (paial agonist) on areceptors, especially a2 in brainstem - Stimulation of a2A receptors in medulla (vasomotor centre) - decrease sympathetic outflow - fall in BP and bradycardia (also due to enhanced vagal tone). Uses of clonidine Hypeension Opioid withdrawal Menopausal syndrome Alcohol withdrawal Smoking cessation Loose motions in diabetic neuropathy