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What is Toll-like receptor associated with virus is and explain in detail?
Toll-like receptors * TLRs in humans recognize PAMPS (pathogen associated molecular pattern) and are usually expressed on APCs. * Interaction between TLRs on APCs and PAMPS on pathogens activation of APCs and presentation of pathogen-derived antigen to T-cells forms a link between the innate and adaptive immune systems. * Activation of TLRs phagocytosis of the pathogen followed by activation of a proinflammatory environment with secretion of cytokines and chemokines. Ref:- Review of Dermatology by Alikhan; pg num:-17,19