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What is The action of non-competitive muscle blockers is affected by - and explain in detail?
Ans. is 'a' i.e., Hypocalcemia Hypocalcemia has following effects It decreases vesicular ACh release at neuromuscular junction. It causes uncoupling of excitation and contraction. o By action 1. it will enhance the effect of both competitive as well as noncompetitive blockers due to unavailibility of ACh. o By action 2. it will enhance the effect of directly acting muscle relaxant (dantroline).