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What is In which of the following tissues is glucose transpo into the cell enhanced by insulin? and explain in detail?
Under conditions of low insulin, most GLUT4 is sequestered in intracellular vesicles in muscle and fat cells.Insulin induces a rapid increase in the uptake of glucose by inducing the translocation of GLUT4 from these vesicles to the plasma membrane.As the vesicles fuse with the plasma membrane, GLUT4 transpoers are inseed and become available for transpoing glucose, and glucose absorption increases.Ref: DM Vasudevan, 7th edition, page no: 320