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What is A patient with depression was given Imipramine for 2 weeks. Relatives noticed increased excitement, colourful clothes, increased talking. What is the next step in management? and explain in detail?
ANS-A. Antipsychotic with Imipramine continuedThe condition from which the patient above is suffering is a bipolar disorder which includes both depression and mania. So in order to treat both antidepressant i.e imipramine is continued along with an antipsychotic such as phenothiazines, thioxanthenes, etc.Antipsychotic or valproate alone cannot reduce the depression and Imipramine alone cannot reduce the mania. Ref: ARVIND ARORA review of psychiatry p.no:111