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What is Acantholysis is due to destruction of : and explain in detail?
Ans. is 'c' Intercellular Substance It is loss of cohesion b/w epidermal cells due to destruction of intercellulare substance. IgG Antibodies are formed against the intercellular substance.Acantholysis occurs in stratum Basale in Pemiphus Vulgaris*Acantholysis is demonstrated by Nikolsky's sign*Acantholytic cells are demonstrated by Tzanck smear*