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What is Intranuclear and intracytoplasmic inclusion bodies are seen in: September 2012 and explain in detail?
Ans. C i.e. Measles virus Inclusion bodies They are nuclear or cytoplasmic aggregates of stainable substances, usually proteins. They typically represent sites of viral multiplication in a bacterium or a eukaryotic cell and usually consist of viral capsid proteins. Examples of viral inclusion bodies in animals are: Intracytoplasmic eosinophilic? - Negri bodies in rabies Guarnieri bodies in Small pox - Henderson-Peterson bodies in Molluscum contagiosum Intranuclear acidophilic? - Cowdry type A in HSV and Varicella zoster virus and Torres bodies in Yellow fever - Cowdry type B in Polio Intranuclear basophilic? - Cowdry type B in Adenovirus - "owl eyes" in CMV Both intranuclear and intracytoplasmic? - Wahin finkeldey bodies in Measles