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What is All of the following are indications for using RU 486, EXCEPT: and explain in detail?
Misoprostol (PGE1) and dinoprostone (PGE2) are two forms of prostaglandins are commonly used for cervical ripening before induction at term. RU-486 or mifepristone is an anti-progestin. It acts primarily as a competitive receptor antagonist for both progesterone receptors. Indications for its usage are, Termination of pregnancy Emergency contraception Prevention of conception Induction of labor For treatment of uterine leiomyomas, endometriosis, meningiomas, and breast cancer. Ref: Levin E.R., Hammes S.R. (2011). Chapter 40. Estrogens and Progestins. In L.L. Brunton, B.A. Chabner, B.C. Knollmann (Eds), Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e.