You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Hyalin emembrane disease presents as and explain in detail?
In hyaline membrane disease the basic pathology is surfactant defeciency.surfactant is a lipoprotein containing phospholipids like phosphatydylcholine and phosphatydylglycerol. Surfactant is produced by type ll alveolar cells of lungs which helps to reduce surface tension in alveoli,in its absence surface tension increases and alveoli tend to collapse during expiration.During inspiration more negative pressure is needed to keep alveoli patent.There is inadequate oxygenation and increased work for breathing. Ref : ESSENTIAL PEDIATRICS,O.P.GHAI,PG NO:143, 7th edition