You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is True statements about osteoblasts are all except: and explain in detail?
Ans: C. Have a plasma membrane showing multiple folds(Ref Gray's 40/e p87, 88, 91)Characteristic of osteoclasts:Plasma membrane showing multiple folds.I.e. ruffled borders are involved in osteocytic resorption.Osteoclasts:Large (40 or more) polymorphic cells.Have upto 20 oval, closely packed nuclei.Howship's lacunae - Lie in close contact with bone surface in resorption bays.Cytoplasm:Contains numerous coated transpo vesicles & microtubule arrays.Involved in vesicles transpo between Golgi stacks & ruffled membrane.Ruffled membrane - Highly infolded cell surface of active osteoclasts at local bone resorption sites.Osteoblasts:Derived from osteoprogenitor (stem) cells of mesenchymal origin.Present in bone marrow & other connective tissues.Proliferate & differentiate after stimulated by bone morphogenetic proteins (BMPs a into osteoblasts prior to bone formation.