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What is 68-years-old man weighing 60 kg has plasma creatinine 3mg/dL. What will be creatinine clearance? and explain in detail?
By Cockcroft & Gault formula Factors influencing 1. Body wt. - Assumed to be d/o muscle mass - Muscle - creatine - creatinine 2. Age - with advancing age, number of functional nephrons decrease Cockcroft & gault formula unreliable in: - 1. Obesity 2. Pregnancy