You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is The earliest clinical manifestation of siderosis bulbi is and explain in detail?
Siderosis bulbi It refers to the degenerative changes produced by an iron foreign body. Sidesosis bulbi usually occurs after 2 months to 2 years of the injury. However, earliest changes have been repoed after 9 days of trauma. Clinical manifestations : 1. The anterior epithelium and capsule of the lens are involved first of all. Here, the rusty deposits are arranged radially in a ring. Eventually, the lens becomes cataractous. 2. Iris. It is first stained greenish and later on turns reddish brown. 3. Retina develops pigmentary degeneration which resembles retinitis pigmentosa. 4. Secondary open angle type of glaucoma occurs due to degenerative changes in the trabecular meshwork. Ref:- A K KHURANA; pg num:-409,410