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What is Gilbe syndrome - True is and explain in detail?
Gilbe&;s disease : It is inherited as an autosomal dominant trait.The defect is in the uptake of bilirubin by liver.Bilirubin level is usually around 3mg/dl, and the patient is asymptomatic except for the presence of mild jaundice. Reduction of hepatic bilirubin glucoronidating activity to about 30% of normal levels.It is detected in the adult life,typically in association with stress,such as an intercurrent illness,strenous exercise,or fasting. Ref : ROBBINS AND COTRAN PATHOLOGIC BASIS OF DISEASES,7 TH EDITION,PG NO:888