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What is A patient with Hb 7 was to be transfused with 2 packs of blood. The first pack was transfused in 2 hours after which vitals were stable and then the transfusion of the next pack was staed . But suddenly the patient develops breathlessness and hypeension. What can be the cause of this sudden reaction? and explain in detail?
Answer- C. transfusion related acute lung injury (TRALI)Transfusion-related acute lung injury (TRALI) is a serious blood transfusion complication characterized by the acute onset of non-cardiogenic pulmonary edema following transfusion of blood products.Hypotension, and fever that develop within 6 hours after transfusion and usually resolve with suppoive care within 48 to 96 hours. Although hypotension is considered one of the impoant signs in diagnosing TRALI, hypeension can occur in some cases.