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What is Alopecia universalis and explain in detail?
Alopecia universalis (AU), also known as alopecia areata universalis, is a medical condition involving the loss of all body hair, including eyebrows, eyelashes, chest hair, armpit hair, and pubic hair. It is the most severe form of alopecia areata. People with the disease are usually healthy and have no other symptoms and a normal life expectancy.

Causes
Alopecia universalis can occur at any age, and is currently believed to be an autoimmune disorder, in which a persons immune system attacks the hair follicles. Genetic factors may contribute to AU, as about 20% of those affected have a family member with alopecia.

Treatment
Many treatments have been explored, including immunomodulatory agents such as imiquimod. Tofacitinib citrate may also have benefits. In June 2014,  a 25-year-old man with almost no hair on his body was reported to have grown full head of hair, as well as eyebrows, eyelashes, and facial, armpit, and other hair, following eight months of treatment.Contact immunotherapy involves the use of contact allergens, such as diphencyprone  and squaric acid dibutylester, to induce an immune response that is thought to oppose the action of cells causing hair loss