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What is HER-2/neu gene causes breast carcinoma due to and explain in detail?
Answer- A. OverexpressionHER2/neu or ERBB2 gene which encodes for Receptor tyrosine-protein kinase erbB-2, also known as CD340.Amplification or over-expression of this oncogene has been shown to play an impoant role in the development and progression of ceain aggressive types of breast cancer.