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What is Centrally acting antihypeensive drugs are all EXCEPT: March 2004 and explain in detail?
Ans. D i.e. Trimethoprim Trimethoprim is structural analogue of the pteridine poion of dihydrofolic acid but, unlike sulfonamides, it blocks the conversion of dihydrofolic acid to tetrahydrofolic acid (active form)by competitively inhibiting the enzyme dihydrofolate reductase.