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What is Type III reaction is- and explain in detail?
Option 2 Type-III hypersensitivity reactions are as a result of excess formation of immune complexes (Ag-Ab complexes) which initiate an inflammatory response through activation of complement system leading to tissue injury: Localized or Ahus reaction Generalized or Systemic type III Reactions, e.g. Serum sickness. Option 1 Type-I: IgE-mediated degranulation of basophils or mast cells. Type-II: IgG Antibodies against cell surface antigen, causing damage by ADCC or complement activation. Option 3 Type-IV hypersensitivity:- It is delayed type (occurs after 48-72 hours of antigen exposure) Cell mediated: Characteristic cells called TDTH cells are the principal mediators