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What is 18 year old girl with primary amenorrhea having a karyotype of 45X0 presents with infantile uterus. What should be done next? and explain in detail?
Primary amenorrhea with karyotype of 45 XO with an infantile uterus is suggestive of TURNER SYNDROME Management Screen for associated abnormalities: cardiac (30% have coarctation of aoa), renal (esp.horseshoe kidney), autoimmune abnormalities (thyroiditis), diabetes, hypeension and hearing loss Growth hormone therapy: accelerate growth velocity and improves final height Gonadal steroids: sta with estrogen therapy and add progesterones to induce pubey