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What is OCPs are C/I in pts receiving: and explain in detail?
Ans. is a, i.e. RifampicinRef: KDT 6th/ed, p317; Novak 14th/ed, p276Interactions of OCPs with other Drugs.Effect of other drugs on OCP's:Drugs reducing the effectiveness of OCPDrugs which increase the plasma level of steroids of OCP* RifampicinQ* CarbamazepineQ* Phenytoin* Ascorbic acid* Acetaminophen* Antifungals like- Griseofulvin- Ketoconazole- ItraconazoleInduce synthesis of cytochromeP450 enzymes in liver.* Ampicillin* TetracyclineKill gut bacteria and cause hydrolysis of steroid glucuronides in intestine.