You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Pendred&;s Syndrome is due to defect in: and explain in detail?
Pendred&;s Syndrome: Consists of congenital sensorineural hearing loss+ goitre Due to defects in sulfate transpo protein (Chromosome 7q) to the thyroid gland and cochlea. Rafetoff Syndrome End organ resistance to T4 Ref: Schwaz 10th edition Pgno: 1534