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What is Which of the following is not a poor prognostic factor in neuroblastoma? and explain in detail?
Unourable prognostic factors in neuroblastoma: Stage 3, 4 Age >18 months Absence of evidence of schwannian stroma and gangliocytic differentiation High Mitosis-karyorrhexis index (>200/5000 cells) Near-diploid (segmental chromosome losses; chromothripsis) MYCN Amplified Chromosome 1p loss Chromosome 11q loss Absent TRKA expression Presence of TRKB expression Mutations of neuritogenesis genes