You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is In the stage of Grey hepatization- and explain in detail?
Ref:Textbook of pathology (Harsh mohan)6th edition,page no. 469 GREY HEPATISATION: LATE CONSOLIDATION This phase lasts for 4 to 8 days Grossly, the affected lobe is firm and heavy. The cut surface is dry, granular and grey in appearance with liverlike consistency .The change in colour from red to grey begins at the hilum and spreads towards the periphery. Fibrinous pleurisy is prominent. Histologically, the following changes are present i)The fibrin strands are dense and more numerous. ii)The cellular exudate of neutrophils is reduced due to disintegration of many inflammatory cells as evidenced by their pyknotic nuclei. The red cells are also fewer. The macrophages begin to appear in the exudate. iii)The cellular exudate is often separated from the septal walls by a thin clear space. iv)The organisms are less numerous and appear as degenerated forms.