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What is Which of the following statement about congenital adrenal hyperplasia is not true - and explain in detail?
Deficiency of 21α hydroxylase is the most common cause of congenital adrenal hyperplasia.
Due to the deficiency of this enzyme there is no synthesis of mineralocorticoid and glucocorticoids in the adrenal cortex.
Decreased mineralocorticoid causes marked sodium loss in the urine resulting in hyponatremia, hyperkalemia acidosis and hypotension.
Due to deficiency of 21α hydroxylase there is increased formation of 17 hydroxyprogesterone which is then shunted into the production of testosterone.
This causes virilisation in females and precocious puberty in males.