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What is Function of LCAT is: and explain in detail?
The cholesterol (cholesteryl) ester forms an integral pa of HDLThe cholesterol from the peripheral tissues is trapped in HDL by a reaction catalyzed by LCATLecithin-cholesterol acyltransferase/ LCAT/ Phosphatidylcholine-sterol 0-acyltransferaseIt conves free cholesterol into cholesteryl ester (a more hydrophobic form of cholesterol)Which is then sequestered into the core of a lipoprotein paicle, eventually making the newly synthesized HDL spherical and forcing the reaction to become unidirectional since the paicles are removed from the surface.The enzyme is bound to high-density lipoproteins (HDLs) and low-density lipoproteins in the blood plasma