You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is All of the following statements about Myasthenia Gravis are true, except: and explain in detail?
Anti-MuSK antibodies are autoantibodies directed against muscle-specific tyrosine kinase (MuSK) Anti-ChR antibodies and Anti-MuSK Antibodies directed against muscle-specific tyrosine kinase (MuSK) Anti-AChR antibodies are the most common antibodies in generalized myasthenia gravis. The pathogenic antibodies aee IgG and are T cell dependent The chief target of the autoimmune attack (Anti-AChR antibodies) in most cases of myasthenia gravis is the skeletal muscle nicotinic acetylcholine receptor (nAChR) The underlying defect is a decrease in the number of available Nicotinic ACh Receptors (nAChR) on the motor end plate at the "Neuromuscular junction" due to an antibody mediated autoimmune attack. Anti-MuSK antibody occurs in about 40% of patients without AChR antibody. Muscle -specific kinase (MuSK) is a protein involved in AChR clustering at neuromuscular junctions. An immune response to muscle-specific kinase (MuSK), can also result in MG, with reduction of AChR demonstrated experimentally. Anti-MuSK antibody occurs in about 40% of patients without AChR antibody. Ref: Harrison&;s 19th edition Pgno: 2701