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What is Poorest prognosis in AML is seen in which cyiogcnetic abnormality- and explain in detail?
Monosomy 7 or paial deletion of the long arm of chromosome 7 (7q-) is a frequent cytogenetic finding in the bone marrow of patients with myelodysplasia (MDS) and acute myelogenous leukemia (AML) Ref Davidson 23rd edition pg 789