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What is Which of the following is not a prodrug? and explain in detail?
(Ref: KDT 6th ed. pg. 24)Drugs that are administered and then converted to the active drug by biologic processes--inside the body are called a prodrug.If an active drug converted to another active metabolite, they are considered as prodrugs.All ACE inhibitors are prodrug EXCEPT Captopril and Lisinopril (Mn = ACL)Other List of prodrugs are (MAMC-LEADS)#Minoxidil, ace inhibitors, mercaptopurine, cyclophosphamide, clopidogrel#Levodopa, enalapril, alpha methyl dopa, dipivefrine, sulfasalazine, sulindac