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What is Which of the following is not a feature of neonatal lupus erythematosus? and explain in detail?
Neonatal lupus erythematosus (NLE) is a disorder caused by the transplacental passage of maternal antibodies. The most frequent clinical manifestations are cutaneous lesions andcongenital hea block (CHB). Approximately 50% of NLE infants manifest skin lesions at bih or occur in the first few weeks of life as an erythematous eruption on the face and periorbital skin (raccoon sign/owl-eye/eye mask). Thrombocytopenia may occur in up to 20% ofcases and does not usually require treatment. The main antibody is Ro/SS-A. Ref: Rook's textbook of dermatology, Edition-8, Page-51.49.