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What is Which antiepileptic drug can lead to this adverse effect: and explain in detail?
Ans. (A) PhenytoinThe figure shows the gum hypertrophy which is caused by phenytoinThe mechanism of action of antiepileptic drugsMain mechanismDrugNa Channel blockersPhenytoinCarbamazepineLamotrigineValproateStimulate GABA-BZD Cl channel complesBarbituratesBenzodiazepinesInhibit GABA transaminaseVigabatrinInhibit GAT-1TiagabineAct on SV2ALevetiracetamOpen K+ ChannelsRetigabineBlock NMDA receptorsFelbamateBlock AMPA receptorsPerampanelBlock L type Ca ChannelsEthosuximide