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What is Efalizumab disrupts the interaction between which of the following adhesion molecules? and explain in detail?
Agents targeting co-stimulatory molecules and under development for psoriasis include: Efalizumab, -A gainst CD11a (LFA-1), which blocks CD11a-ICAM-1 binding and may inhibit lymphocyte binding to endothelium the same mechanism. Alefacept - Inhibiting the normal CD2/LFA-3 interaction.