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What is Clonus is due to? and explain in detail?
Ans. A Upper motor neuron damageRef: Ganong, 25th ed. pg. 233Clonus is characterized by repeated rhythmic contractions of muscle subjected to sudden maintained stretch.It is Caused by* Increased Gamma motor neuron discharge* Spinal cord injury causing damage to Renshaw cell which is an inhibitory inter-neuron.Conditions in Which Clonus is seen:1. Amyotrophic lateral sclerosis2. Stroke3. Multiple sclerosis4. Spinal cord damage5. Hepatic encephalopathyClonazepam and botulinum toxin is useful in management of clonus.