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What is A 50 years old female on junk food diet presented with point hemorrhages in scalp, bleeding in joints and erythemataous lesions in the skin. X-ray of knee joint was suggestive of hemahrosis. Problem lies with: and explain in detail?
Answer- A. Hydroxylation of proline and lysineVitamin C is required for post-translational modification of lysine and proline in collagen synthesisHydroxyproline is formed by post-translational hydroxylation catalyzed by prolyl hydroxylase, whose cofactors are ascorbic acid and Keto- alpha glutarate.