You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is All are true regarding Toxoplasmosis, except ? and explain in detail?
Ans. is d i.e., Not infective in third trimester in pregnancy . The incidence of transplacental infection is highest in third trimester but the infant is not severely affected. . The presence of IgM (which does not cross placenta) in the infants circulation is diagnostic. Clinical manifestation of toxoplasmosis 1. Adults a) Immunocompetant host - Asymptomic in 90% of patients. - M.C. clinical featur is cervical lymphadenopathy. - Other less common manifestations are pneumonia, myocarditis, encephalitis. b) Immunocompromised host - M.C. signs and symptoms are principally within CNS Encephalopathy, Meningoencephalitis. 2. Children a) Congenital - May present with hydrocephalus, microcephaly mental retardation, deafness, blindness, epilepsy. - Intracerebral calcification may occur. b) Acquired - Mostly asymptomatic - C/Fs are chorioretinitis (most common), cataract, glaucoma.