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What is The cardiovascular side effect of Dexmedetomidine is following and explain in detail?
Dexmetetomidine is a highly selective alpha2 - adrenoceptor against thus can cause hypotension and Bradycardia. Dexmedetomidine * Highly selective alpha - 2 adrenoreceptor agonist * Used mainly as IV adjunct during induction and /or maintenance of general anesthetics * Minimal respiratory and cardiovascular depression * Good sedation , good analgesic, sympatholytic effects * Selectivity for alpha1: alpha 2 receptors is 1:1640