You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Acute poststreptococcal glomerulonephritis is characterised by which of the following hypersensitivity reactions? and explain in detail?
Acute poststreptococcal glomerulonephritis is a well-known immune complex disease. Its onset occurs several weeks after a group A alpha hemolytic streptococcal infection, paicularly of the skin, and often occurs with infection due to nephritogenic types of streptococci. The complement level is typically low, suggesting an antigen-antibody reaction with consumption of complement. Lumpy deposits of immunoglobulin and complement component C3 are seen along glomerular basement membranes stained by immunofluorescence, suggesting antigen-antibody complexes. It is likely that streptococcal antigen-antibody complexes are filtered out by glomeruli, fix complement, and attract neutrophils. This series of events results in an inflammatory process that damages the kidney. Ref: Brooks G.F. (2013). Chapter 8. Immunology. In G.F. Brooks (Ed), Jawetz, Melnick, & Adelberg's Medical Microbiology, 26e.