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What is Inhalation of asbestosis particle of 15 micro meter will cause: and explain in detail?
Ans: A (Mesothelioma) Ref: Robbins, 7 ed, p. 768-769Exposure to asbestosis is associated with incidence of malignant pleural tumours (mesothelioma)Types of asbestosis:Serpentine (curly and flexible fibres) e.g.: chrysoliteAmphibole (straight stiff and brittle) e.g.: crocidolite.Amphiboles are more pathogenic than chrysolitesThe greater pathogenicity of amphibole is apparently related to their aerodymanic properties and solubility. The straight stiff amphiboles may align themselves in the airstream and delivered to the deeper long tissues, where they can penetrate epithelial cells and reach interstitium.Length of amphibole also play a role in pathogenicity, those longer than 8 micro meter and thinner than 0.5 micrometer being more injurious than shorter thicker ones.