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What is Which is a serine protease: and explain in detail?
Ans. b. Trypsinogen 1Inherited predisposition to pancreatitisGene (chromosome location)Protein productFunctionPRSSl (7q34)Serine protease 1 (trypsinogen 1)Cationic trypsin. Gain-of-function mutations prevent self- inactivation of trypsinSPINK1 (5q32)Serine peptidase inhibitor, Kazal type 1Inhibitor of trypsin. Mutations cause loss-of-function, increasing trypsin activityCTRC (lp36)Chymotrypsin C (caldecrin)Degrades trypsin, protects the pancreas from trypsin-relatedinjuryCPA1 (7q32)Carboxypeptidase A1Exopeptidase involved in regulating zymogen activation