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What is Orphan annie eye nuclei appearance is characteristic of- and explain in detail?
Orphan Annie eye nuclei is a feature of papillary carcinoma of thyroid. The nuclei of cells in papillary carcinoma thyroid has finely dispersed chromatin . Thus it is optically clear and shows ground glass or Orphan Annie eye nuclei. Ref: Robbins and cotrans 9e Pg 1095