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What is Live attenuated vaccine can be given to: and explain in detail?
Ans. (a) Children under 8 yearsRef.: K. Park 23rd ed. /103, 21st ed /28* Live vaccines are prepared from live (generally attenuated) organisms. Generally live vaccines are more potent then killed vaccines . In case of administration of live vaccines usually require single dose except polio vaccine which require 3 doses .* Live vaccines are usually contraindicated in persons with immunodeficiency disorders or persons with leukemia, lymphoma, malignancies, or because of therapy with alkylating agents, corticosteroids, radiotherapy, antimetabolite drugs.* Pregnancy is the another contraindication unless risk of infection exceeds the risk of harm to the fetus .