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What is Translocation seen in Ewing's sarcoma is: and explain in detail?
Ans: B. t(11,22)Genetic exchange between chromosomes can cause cells to become cancerous. Most cases of Ewing's sarcoma (85%) are the result of a translocation between chromosomes 11 and 22, which fuses the EWS gene of chromosome 22 to the FLI1 gene of chromosome 11. Other translocations are at t(21;22) and t(7;22).