You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Earliest symptom of Tay sach disease and explain in detail?
Ans. is 'a' i.e., Exaggerated stale response Tay-Sach diseaseClinical symptoms are usually evident in the first year of lifeInitial signs are not dramatic and present as enfeeblement, spasticity and slow development.An exaggerated stale response to sound may be the most significant early sign of which a parent is aware.Other features are mental retardation, deterioration of vision and early death.