You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is RNA participates directly in all of the following except: and explain in detail?
POST TRANSLATIONAL MODIFICATIONS OF PROTEINS
The proteins synthesized in translation are, as such, not functional. Many changes take place in the polypeptides after the initiation of their synthesis or, most frequently, after  the protein synthesis is completed. These modifications include protein folding, trimming by proteolytic degradation, intein splicing and covalent changes which are collectively known as modifications.