You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is During autopsy of a patient died due to suspected myocardial infarction, the hea was stained with triphenyltetrazolium tetrachloride dye. What will be the color of the ble myocardium? and explain in detail?
Ans: B(Ref: Robbins 9/e p544)Triphenyltetrazolium chloride (TTC) stain:Impas a brick-red color to intact, non-infracted myocardium where dehydrogenase enzymes are preserved.Acute Ml - Early morphologic recognition:Infarct preceding death by 2 to 3 hours:Highlighting area of necrosis by immersion of tissue slices in a solution of triphenyltetrazolium chloride.Gross histochemical stain impas brick-red color to intact, non-infarcted myocardium where lactate dehydrogenase activity is preserved.Dehydrogenases leaks out damaged membranes of dead cells.Hence, an infarct appears as an unstained pale zone.By 12 to 24 hours after infarction:MI identified grossly as a reddish-blue area of discoloration.Caused by stagnated, trapped blood.By 2 days to 10 days:Infarct becomes progressively more sharply defined, yellow-tan & soft.By 10 days to 2 weeks:Rimmed by a hyperemic zone of highly vascularised granulation tissue.Over succeeding weeks:Fibrous scar