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What is In G6PD deficiency, which cells are more prone for hemolysis? and explain in detail?
a. Older red cells(Ref: Nelson's 20/e p 2335, Ghai 8/e p 339)Because mature red cells do not synthesize new proteins, G6PD enzyme activity falls quickly to levels inadequate to protect against oxidant stress as red cells age. Thus, older red cells are much more prone to hemolysis than younger ones.