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What is Phlegmon; all are true except and explain in detail?
Cellulitis (Phlegmon)
→ Diffuse swelling of face with no defined margins.
→ The tissue are tender, painful, hard to touch.
→ Pain, fever, malaise, exhaustion, all features are more aggressive.
→ It takes 3-7 days to develop.
→ Spreading factor of Duran and Reynals.
→ Rapidly spreading infection of subcutaneous tissue due to micro-organism which are capable to produce hyaluronidase which breakdown intercellular cementing substance hyaluronic acid.
→ Streptococci is more involved in causing cellulitis than staphylococci.
→ Streptocci produce enzymes such as : Streptokinase (fibrinolysin), hyaluronidase, and streptodornase.
→ These enzymes breakdown fibrin and connective tissue ground substance and lyse cellular debris. Thus facilitate rapid spread of bacteria along the tissue planes.