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What is Fatal familial insomnia is associated with: and explain in detail?
Ans. is 'a' i.e., Prion diseaseFatal familial insomnia: Patients with this illness present with intractable insomnia, dysautonomia, dementia and motor paralysis. Death occurs within 6 months to 3 years following presentation. The clinical presentation of the disease, however, varies widely; hence definitive diagnosis of the condition is made by genotyping.