You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is In acute myeloid leukemia, Auer rods are numerous in: September 2009 and explain in detail?
Ans. B: M3 The diagnosis of AML is based on the presence of at least 20% myeloid blasts in the bone marrow. Myeloblast have delicate nuclear chromatin, two to four nucleoli, and more voluminous cytoplasm than lymphoblasts. The cytoplasm often contains fine, peroxidase-positive azurophilic granules. Auer rods, distinctive needle like azurophilic granules, are present in many cases; they are paicularly numerous in AML with the t(15;17) (acute promyelocytic leukaemia-M3).