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What is In Bater's Syndrome, which of the following is not seen- and explain in detail?
Bater's syndrome - There is loss of transpo function of Thick ascending loop of henle(TALH) Segment of nephron which results in hypokalemic metabolic alkalosis classic BS- typically suffer from polyuria and polydypsia due to reduction in renal concentrating ability . Increase in urinary calcium excretion 20% are hypomagnesemic. Marked activation of RAAS. Antenatal BS- They suffer from severe systemic disorder characterized by marked electrolyte wasting, polyhydramnios ,hypercalciuria with nephrocalcinosis . Ref:Harrison 20 th edition pg no 306.