You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A patient with cancer received extreme degree of radiation toxicity. Fuher history revealed that the dose adjustment of a paicular drug was missed during the course of radiotherapy. Which of the following drugs required a dose adjustment in that patient during radiotherapy in order to prevent radiation toxicity - and explain in detail?
Ans. is 'b' i.e., Dactinomycin o The patient was most probably taking a radiosensitiser i.e., drugs which increases the toxicity due to radiotherpy. o The dose of these drugs should be decreased during radiotherapy o Among the drugs given in the question Actinomycin D or Dactinomycin is a radiosensitizer o Hypoxic cells are resistant to radiotherapy o Augmentation of oxygen is the basis of radiosensitization