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What is True about primary CNS lymphoma - and explain in detail?
Primary CNS Lymphoma Lymphomas in the brain may occur as a pa of disseminated non-Hodgkin's lymphoma or may be a primary CNS lymphoma. Primary CNS lymphoma has a poor prognosis. MORPHOLOGIC FEATURES. Grossly, the tumor is frequently periventricular in location and may appear nodular or diffuse. Microscopically, the features are as under: i) Characteristically, the tumor grows around blood vessels i.e. has an angiocentric growth pattern. Reticulin stain highlights this feature well. ii) Typically, CNS lymphomas are diffuse, large cell type with high mitotic activity. iii) They are generally b-cell type. Ref: TEXTBOOK OF PATHOLOGY 6th EDITION - HARSH MOHAN PAGE NO:889