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What is Contractile dysfuncation seen in which type of cardiomyopathy? and explain in detail?
Dilated cardiomyopathy (DCM) is characterized by progressive cardiac dilation and contractile (systolic) dysfunction, usually with concurrent hyperophy; regardless of cause, the clinicopathologic patterns are similar. DCM results in systolic (contractile) dysfunction. Causes include myocarditis, toxic exposures (e.g., alcohol), and pregnancy. In 20% to 50% of cases, mutations affecting cytoskeletal proteins are responsible. Ref Harrison 20th edition pg 1445