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What is More than 90% of this drug is excreted in the urine in intact form. Because its urinary solubility is low, patients should be well hydrated to prevent nephrotoxicity. The drug is: and explain in detail?
- Both indinavir and acyclovir can cause nephrotoxicity and renal stone formation. - But indinavir is metabolized mainly in the liver and acyclovir is excreted unchanged in the urine. - Therefore patients should be well hydrated to prevent nephrotoxicity of acyclovir.