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What is Which of the following is associated with an intrinsic defect in RBC membrane and explain in detail?
Ref Robbins 9/e p632regarding hereditary spherocytosis: this inherited disorder is caused by intrinsic defects in the red cell membrane that render red cells sheroid ,less deformable, and vulnerable to splenic sequestration and destruction Other disorders with intrinsic defect in red cell membrane are hereditary elliptocytosis and abetalipoproteinemia