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What is In a patient with a vesicle on shin. Microscopy on Tzank smear showed giant cells. Causative agents is: and explain in detail?
Ans. (b) Le Varicella zoster Multinucleated giant cells and type a intranculear inclusion bodies may be seen in smears prepared by scraping the base of early vesicles (Tzank smears) and stained with toludine blue, Giemsa or Papanicolou stain" Note: Electron microscopy of vesicle fluid can demonstrate the typical virus