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What is |ed maternal serum a-FP is seen in: and explain in detail?
Ans. is b, i.e. Trisomy 21Ref. Williams Obs. 25/e, p 287; Fernando Arias 2/e, p 38Low levels of MSAFP (< 0.25 MOM) are seen in:Devils: Diabetes mellitusG: Gestational trophoblastic diseaseO: Overestimated gestational age Maternal ObesityA: AbortionT: TrisomyNote: The list given in the Williams Obs. 25/e, p 291 -- Includes fetal death both in causes of increased and decreased AFP. But Fernando Arias 2/e, p 38 specifically includes -- IUD in the causes of increased AFP and Blighted ovum/Abortion in the causes of decreased AFP