You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which of the following is NOT associated with Crohn's disease: and explain in detail?
Ans. (c) Toxic megacolonRef. Harrison's 17th ed. Ch. 289* Crohn's disease is a chronic, recurrent disease characterized by patchy transmural inflammation involving any segment of the gastrointestinal tract from the mouth to the anus but most common site is Ileum.* Crohn's disease is one of the two main forms of Inflammatory bowel disease and is also known as Granulomatous colitis.* Earliest manifestation is Apthous ulcers.* Skip lesions, stricture formation, string sign of kantor is also seen.* Hallmark feature of crohn's is fistula formation.* Cobble stone appearance is seen on X-Ray.* NOTE: Toxic mega colon is seen in Crohns disease but most commonly toxic megacolon is seen in Ulcerative colitis.