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What is Not true about bone metastasis and explain in detail?
Ans is 'd' ie soft tissue sarcomas causes bony metastasis Most common cause of osteoblastic metastasisIn males--- Prostate Cancer In Females-- Breast CancerSkeletal sites most frequently involvedSpine > proximal femur > pelvis > ribs > sternum > proximal humerus > skullLytic expansile metastasis seen inRenal Cancer Thyroid carcinomasOsteolytic lesions are associated with hypercalcemia and excretion of hydroxyproline - containing peptides.Osteoblastic lesions are associated with increased levels of serum alkaline phosphatase.Metastasis distal to knee and elbow is rare and usually arises from a primary tumors of theBronchus Colon or Bladder