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What is Which of the following induction agent produce cardiac stability in coronary aery disease patients? and explain in detail?
Cardiovascular stability after induction is a major advantage of etomidate over either barbiturates or propofol. Induction doses of etomidate typically produce a small increase in hea rate andl little or no decrease in blood pressure or cardiac output. Etomidate has little effect on coronary perfusion pressure while reducing myocardial O2 consumption. Hence it is best suited to maintain cardiovascular stability in patients with coronary aery disease, cardiomyopathy, cerebral vascular disease, or hypovolemia. Ref: Patel P.M., Patel H.H., Roth D.M. (2011). Chapter 19. General Anesthetics and Therapeutic Gases. In L.L. Brunton, B.A. Chabner, B.C. Knollmann (Eds), Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e.