You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is In cap stage, regulating factor for cusp shape formation is present in and explain in detail?
Enamel Knot: The cells in the center of the enamel organ are densely packed to form enamel knot.
Enamel cord: It is the vertical extension of the enamel knot.
Enamel Septum: The enamel cord extends to meet the outer enamel epithelium and form enamel septum.
Enamel Navel: It is the small depression at the point of meeting of enamel cord and outer enamel epithelium.
Enamel niche is the apparent structure created by the plane of histological sections cutting through a curved dental lamina so that mesenchyme is surrounded by the dental epithelium. It appears as a double attachment of dental lamina to the overlying epithelium.

Recent studies shows that enamel knot acts as a signaling center expressing growth factors which play an important role in determining the shape of the tooth