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What is Detection rate of down syndrome with first trimester screening with NT, PAPP-A and hCG is and explain in detail?
Selected Down Syndrome Screening Strategies and Their Detection RateScreening testDetection rateQuadruple screen 80-82%First trimester screenNT alone64-70%NT, hCG, PAPP-A80-84%Integrated screening94-96%Sequential screeningStepwise92%Contingent91%Cell-free DNA91%(Ref: William's Obstetrics; 25th edition)