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What is Which vitamin deficiency causes excretion of xanthurenic acid? and explain in detail?
Pyridoxine deficiency causes the increased excretion of xanthurenic acid Pyridoxal phosphate is required for the synthesis of niacin from tryptophan.Kylureninase is a dependent enzyme.Hence in Pyridoxine deficiency there is a less production of niacin.Moreover, kylurenine is not conveable fuher which is metabolised to xanthurenic acid and excreted through urine. REFERENCE : DM.VASUDEVAN.Textbook of Biochemistry.6th edition Page no 397