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What is Hypeension with hypokalemic alkalosis is seen in? and explain in detail?
Liddle syndrome Gain of function of epithelial Na+ channels. More salt & water accumulating in body - Hypeension Loss of K+ and H+- Hypokalemic alkalosis Gitelman Defect in DCT Salt wasting, polyurea - BP cannot be | Baer Defect in thick ascending limb of loop of Henle Salt wasting, polyuria Normotension or | B.P | Aldosterone (2deg Aldosteronium) Hypokalemic, M. Alkalosis Fanconi syndrome/Renal tubular acidosis Type 2 Etiology- Wilson disease/Expiry date Tetracycline C/F: - Bicarbonaturia, salt wasting, M. Acidosis