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What is Eirenz limits HIV infection by: and explain in detail?
Eirenz is a NNI which acts as an allosteric (non-competitive) inhibitor of HIV reverse transcriptase. It is more potent than zidovudine on HIV-1, but do not inhibit HIV-2. If used alone, viral resistance develops rapidly by point mutation of the enzyme; therefore it should always be combined with 2 other effective drugs. S/E of Eirenz : Headache, rashes, dizziness, insomnia, neuro-psychiatric symptoms