You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A 35-year-old HIV positive patient comes with intractable diarrhea, crampy, abdominal pain and vomiting. Biopsy of small intestine was taken which shows cyst <10 um as given below. What is the appropriate diagnosis? and explain in detail?
- Kinyoun stain positive and clinical features like diarrhea in a immunocompromised individual highly suggestive of organism - Cryptosporidium parvum. - Its oocyst is of size 2-6 micron and it is pink coloured. - Cryptosporidium, microsporidia, and Isospora belli are the most common oppounistic protozoa that infect the GI tract and cause diarrhoea in HIV-infected patients. - Diarrhoea is accompanied by crampy abdominal pain, nausea and/or vomiting. - Diagnosis- stool Cryptosporidium examination or biopsy of the small intestine. - Diarrhoea is noninflammatory, and the characteristic finding is the presence of oocysts that stain with acid-fast dyes. - Treatment: - 2000 mg/d of nitazoxanide (NTZ)