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What is Which of the following drug is specifically for Her 2 positive breast carcinoma is: and explain in detail?
Monoclonal antibody against HER2/neu receptor are:- Trastuzumab Peuzumab S/E:- Cardiotoxic Tamoxifen:- Antagonist on estrogen receptor expressed in mammary tissue. - Agonist on estrogen receptor in bone - Useful not only in treatment and prophylaxis of breast cancer but also in prevention of osteoporosis Exemestane:- a steroid molecule, irreversible inhibitor of aromatase(enzyme required for estrogen synthesis) Fulvestrant:- Pure estrogen receptor antagonist(Selective estrogen receptor down regulator)