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What is An 8 year old child with acute lymphadenopathy, fever, 20% lymphocytosis indicates the diagnosis of ? and explain in detail?
Ans. is 'a' i.e., Infectious mononucleiosis Here the question seems incomplete. Most probably they have asked about atypical lymphocytosis. Infectious mononucleiosis is characterized by classic triad of : Fever, Sore throat, Posterior cervical lymphadenopathy. This classic triad is seen in > 80% of the patients. The W.B.C. count is characteristically increased. Lymphocytosis is demonstrable with 10-20% of them being atypical. The atypical lymphocytes are called Downey cell. These cells have higher cytoplasm to nucleus ratio.