You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Drug of choice for precocious puberty in girls is: and explain in detail?
Ans. (A) GnRH analogue(Ref: Harrison 19th/2380, KDT 8/e p264)Long-acting gonadotropin releasing hormone (GnRH) agonists are the current therapy of choice for central precocious puberty. In girls, mostly central precocious puberty is seen.GnRH agonists are not effective as therapy for peripheral precocious puberty. Androgen antagonists, spironolactone, aromatase inhibitors (Anastrozole and Letrozole), ketoconazole, and medroxyprogesterone acetate are used to treat peripheral precocious puberty.