You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is For initiation of HAART, following is generally evaluated and explain in detail?
(D) All of the above > The indication for antiretroviral therapy is based on the clinical assessment, CD4+ T-cell count, and viral load. These three important factors determine whether therapy should be started or if it can still be deferred, starting therapy in asymptomatic patients> Below 200 CD4+ T-cells/pl treatment should be started as soon as possible.> "As soon as possible" does not mean "immediately": one should still take the time to get acquainted with the patient, give proper counseling, start prophylaxis in advance, and undergo diagnostic procedures (fundoscopy) - it's not usually a question of having to start within a few days!> Above 200 CD4+ T-cells/pl, there is even more time - the individual course of the CD4+ T-cell count is important. Beware the percentage values!> A decrease of more than 80-100 CD4+ T-cells/pl per year is too much! Don't delay too long in such patients!> Because of considerable variability a single CD4+ T-cell count (especially when in the range of 200-350/pl) should be repeated before starting therapy.> Above 350 CD4+ T-cells/pl: wait, but continue to monitor at least every three months.> The higher the viral load, the more frequent checks ofCD4+ T-cell counts are necessary: > 100,000 copies/ml, testing should be performed at least every two months.> Initiation of treatment may be justified at levels above 350 CD4+ T-cells/pl - if viral load is very high, CD4+ T-cell count is decreasing rapidly or the patient requests it (after careful counseling).> A 25 year-old patient with 100 CD4+ T-cells/pl and a viral load of 100,000 copies/ml has a risk of approximately 10 % for developing AIDS within six months - for a 55 year-old, this level of risk is reached at 150 CD4+ T-cells/pl and a viral load of 30,000 copies/ ml