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What is Drug of choice for neurocysticercosis is: and explain in detail?
Out of the two anthelmintics effective in killing cysticerci, albendazole is now preferred over praziquantel for the following reasons: * The course of treatment is shoer (8-15 day) compared to praziquantel (15-30 days). * Cure rates in terms of resolution of symptoms and disappearance of cysts are higher (75-85% with albendazole) than praziquantel (50-60%). * Coicosteroids (which have to be given concurrently) enhance the absorption of albendazole, but lower the blood levels of praziquantel. * Albendazole is cheaper. ESSENTIALS OF PHARMACOLOGY page no. 856