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What is Carbamoyl phosphate intermediates the synthesis of and explain in detail?
(B) Urea & Pyrimidine # Biosynthesis of urea begins with the condensation of CC>2, NHs and ATP to form carbamoyl phosphate, a reaction catalyzed by carbamoyl phosphate synthase I which is a mitochondrial enzyme, and rate limiting or pacemaker enzyme and the enzyme is active only in the presence of its allosteric activator N-acetylglutamate, which enhances the affinity of synthase for ATP.