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What is Which of the following is responsible for the inactive state of Phosphorylase b? and explain in detail?
Insulin increases the uptake of glucose leading to the increased formation of glucose 6-phosphate which is an inhibitor of phosphorylase kinase, which in-turn is needed for the activation of Phosphorylase b. Ref: Lippincott's Biochemistry, 5th Edition, Pages 132, 133, 311 ; Harper's Textbook of Biochemistry, 27th Edition, Pages 161, 162, 163