You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which of the following is an inhibitor of RNA polymerase in eukaryotes ? and explain in detail?
RNA polymerase II enzyme is inhibited by a-amanitin in eukaryotes. a-amanitin is a potent toxin produced by the poisonous mushroom Amanita phalloides (sometimes called "death cap"). a-Amanitin forms a tight complex with the polymerase, thereby inhibiting mRNA synthesis and, ultimately, protein synthesis. Rifampicin inhibits the prokaryotic DNA dependent RNA polymerase Reference: Harpers illustrated biochemistry 30th edition