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What is TH1 is involved in w hich type of hypersensitivity? and explain in detail?
* Delayed type of hypersensitivity is mediated by T cell dependant effector mechanisms involving both CD4+ TH1 cells and CD8 Cytotoxic T cells.* Antibodies do not play a role in type IV hypersensitivity reactions. The activated TH1 cells release Cytokines that will cause accumulation and activation of macrophages which will cause local damage.* TH 2 cells release IL-4 and are involved in Type 1 Hypersensitivity reaction.