You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Negative pressure wound therapy (NPWT) is used in: and explain in detail?
VACCUM ASSISTED CLOSURE/ NEGATIVE PRESSURE WOUND THERAPY (NPWT) NPWT Promotes wound healing by applying a vacuum through a special sealed dressing. Continued vacuum draws out the fluid from wound & increases blood flow to the area. Vaccum may be applied continuosly or intermittently, depending upon the types of wound being treated & clinical objectives. Negative pressure of -125 mm Hg is used Dressing should be changed 2-3 times/week Primary Effects of NPWT on Wound Healing Macrodeformation Drawing the wound edges together leading to contraction Stablization of wound environment Wound protected from outside micro- organisms in a warm & moist envirnoment Reduced edema With removal of soft tissue exudates Microdeformation Leading to cellular proliferation on the wound surface Contraindications for NPWT Use Malignancy in the wound Untreated osteomyelitis Non-enteric & unexplored fistula Necrotic tissue with eschar