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What is Antidepressant drug that can cause neuroleptic malignant syndrome and tardive dyskinesia is:- and explain in detail?
Amoxapine acts by blocking D2 receptors in addition to the inhibition of NA reuptake. It possesses antipsychotic propeies as well It is a metabolite of antipsychotic drug; loxapine. Due to blockade of D2 receptors, there is risk of extrapyramidal symptoms like dystonia, neuroleptic malignant syndrome, tardive dyskinesia etc.