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What is Which of the following oncogenes is a growth factor? and explain in detail?
The 'sis' oncogene is a growth factor. The protooncogene 'sis' encodes the ( b chain of) Platelet Derived Growth Factor (PDGF). Ref: Robbin's Illustrated Pathology, 7th Edition, Pages 293, 295; Cancer: Principles and Practice of Oncology, 6th Edition, Page 13