You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Predisposing features for germ cell tumour? and explain in detail?
Ans. is 'a' i.e., Cryptorchidism; 'b' i.e., Testicular feminising syndrome; 'c' i.e., Klinefelter syndromeThe predisposing factor of germ cell tumors of testes are :1. Cryptorchidism2. Testicular feminisation syndrome3. Klinefelter syndrome4. Excess 12P copy number either in the term of i(12P) or increased 12P an aberranthy banded marker chromosome.o In most large testicular tumour approximately 10% associated with Cryptorchidism.o Abdominal cryptorchid testes are higher risk than inguinal cryptorchid testes.o Early orchiopexy before pubey reduced the risk of GCT.o Klinefeleter's syndrome is associated with mediastinal GCT.o An ischromosome of sho arm of chromosome 12. is pathognomic of GCT in all histological types.