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What is Non-competitive enzyme inhibition leads to: (PGI Nov 2010) and explain in detail?
Ans: B (Vmax|) Non-Competitive inhibition The inhibitor reacts with an adjacent site and not with the catalytic site, but alters the enzyme in such a way that it loses its catalytic property. Thus Km is unchanged but Vmax is reduced? If the inhibitor can be removed from its site of binding without affecting the activity of the enzyme, it is called as Reversible -Non competitive inhibitionQ