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What is Lipid lowering drug that significantly reduces lipo protein-a levels is? and explain in detail?
Nicotinic acid is B3 vitamin which in higher doses reduce plasma lipids. When nicotinic acid is given, TGs and VLDL decrease rapidly, followed by a moderate fall in LDH-CH and total CH. It also reduces Lp(a) which is considered more atherogenic. It acts by inhibiting lipoprotein lipase produced from the endothelium From essentials of medical pharmacology K D Tripathi 7th edition page no 640