You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Trans-placental spread is least associated with ? and explain in detail?
HSV infection may be acquired in utero, during the bih process,or during the neonatal period. Intrauterine and postpaum infections occur infrequently. Most cases of neonatal herpes result from maternal infection and transmission usually during passage through a contaminated infected bih canal of a mother with asymptomatic genital herpes. TRANSPLACENTAL spread is associated with the following - Toxoplasmosis,syphilis, parvovirus,rubella, cytomegalovirus (TORCH)infections. some other bacterial infections also occur transplacentally like TREPONEMA pallidum, LISTERIA monocytogenes. Reference: Nelson textbook of pediatrics 19th edition Page 1101