You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which of the following tumours have an increased elevation of placental alkaline phosphatase in the serum as well as a positive immunohistochemical staining for placental alkaline phosphatase - and explain in detail?
Alkaline phosphatase - There are four major sources of Alkaline phosphatase in the body. These are:-

Liver       
Bone    
Intestine
Placenta

So the normal serum alkaline phosphatase consists of 4 isoenzymes secreted from the above-mentioned sites.
Placental alkaline phosphatase is elevated in the following conditions -
(a) Seminoma  
(b) Choriocarcinoma
(c) Third trimester of pregnancy
About other options -
In liver diseases and hepatocellular carcinoma the alkaline phosphatase elevated is of liver origin. Similarly the alkaline phosphatase elevated in bony diseases is due to some pathology in bone.