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What is Degradation of a substance takes place in which part of the cell: and explain in detail?
Ans: c (Lysosome) Ref: Vasudevan, 4th ed,p. 17Degradation of a substance takes place in lysosomes. Phagosomes fuse with lysosomes to form phagolysosomes, inside which particles are digested.Lysosomal storage disease:DiseaseEnzyme deficiencyMajor accumulating metaboliteGlycogenosesType II (Pompes disease)Lysosomal glucosidaseGlycogenSphingolipidoses GM 1GMl gangliosideGM 1 gangliosideGM 2Beta galactosidaseGM 2 gangliosideTay sachs diseaseHexosaminidase A Sulfatidoses Gaucher diseaseGlucocerebrosidaseGlucocerebrosideNiemann Pick diseaseSphingomyelinaseSphingomyelinMucopolysaccharidoses MPS 1 (Hurler)L-IduronidaseHeparan sulfate Dermatan sulfateMPS 11 (Hunter)L- Iduronosulfate sulfataseHeparan sulfate Dermatan sulfate