You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which of the following infectious disease is transmitted through Rat? and explain in detail?
Leptospirosis is a zoonotic disease. Human to human transmission does not occur. The most impoant sources of transmission of infection to humans are rats, dogs, cattle, and pigs. Leptospira: They are tightly and regularly coiled with characteristic hooked ends. It is highly motile. The clinical hallmarks of this disease as an acute process IS characterized by splenomegaly, jaundice, and nephritis. Weil's disease is characterized by variable combinations of jaundice, acute kidney injury, hypotension, and hemorrhage. Ref: Harrison's Principles of Internal Medicine, 18th Edition, Chapter 171