You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Intractable secondary glaucoma is seen in – and explain in detail?
Iris melanomas may be of two types :-

Circumscribed/ Nodular: - It is the most common type which presents as a pigmented spot on the iris. Glaucoma is less common and usually treatable.
Diffuse iris melanoma: - Present as a unilateral dark iris (hyperchromic hetrochromia). The tumor has diffusely infiltration pattern of growth and invades the intertrabecular spaces, and plugs the drainage mechanism. This results in intractable secondary glaucoma.