You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Serum alkaline phosphatase levels are increased in: and explain in detail?
Laboratory Findings in Paget's disease:
The serum calcium and serum phosphorus levels are usually within normal limits, even in cases of advanced osteitis deformans. The serum alkaline phosphatase level may be elevated; however, to extreme limits. Values as high as over 250 Bodansky units have been reported, particularly in patients in the osteoblastic phase of the disease, when there is rapid formation of new bone and when there is polyostotic involvement. In fact, there is no other disease of bone in which the serum alkaline phosphatase level may be as high as in Paget’s disease.
Ref: Shafer's textbook of oral pathology 7th edition page 733