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What is Recalcitrant acne is treated by: and explain in detail?
The European S3 guidelines recommend isotretinoin for the treatment of severe recalcitrant acne or moderate acne that has failed to respond to conventional antibiotic therapies. Retinoids - Isotretinoin : D.O.C for severe / gd 4 / nodulocystic acne/ acne conglobata. Dose 0.5 - 1 mg / kg body weight to be given till cumulative dose of 120-150mg/kg body weight.