You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A 13 year girl with fatigue and weakness was found to be having reduced hemoglobin. Her MCV 70FC, MCH22pg and RDW 28. What is her likely diagnosis and explain in detail?
Decreased heamoglobin with the clinical features of fatigue and weakness is diagnostic of anemia.
MCV is 70% Ft, So, microcytosis is present (normal MCV is 80-96ft)
MCH is 22pg, so, decreased MCH is suggestive of hypochromic anermia (normal MCH is 27 - 33 pg)
Red Cell distribution with (RDW) is the co efficient of variation of size of RBC's normal value is 11.5 - 14.5 it is an indicator of anisocytosis which may present in IDA as well as heamolytic anemia.
In early iron deficiency anemia, RDW increased along with low MCV white in beta thalassemia trait RDW is normal with low MCV, thus distingguishing from each other.