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What is Predisposing factor for esophageal cancer is all except: and explain in detail?
* External beam irradiation but not mediastinal fibrosis is risk factor for esophageal cancer. * HPV DNA is found frequently in esophageal squmaous cell carcinoma in high incidence regions. OTHER RISK FACTORS PREDISPOSING TO CARCINOMA OF ESOPHAGUS: - SQUAMOUS CELL CARCINOMA: Alcohol & tobacco use Intake of nitrosamines Caustic esophageal injury Deficiency of Zn/Mo/Vit A/ Vit C Achalasia Plummer-Vinson syndrome Frequent consumption of very hot beverages Previous radiation therapy to mediastinum Esophageal diveicula Tylosis et palmaris - ADENOCARCINOMA: Barrett's esophagus