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What is HLA complex in humans is located on? and explain in detail?
Ans. b (Short arm of chromosome 6). (Ref Harrison's medicine 16th ed. 1930)MAJOR HISTOCOMPATIBILITY COMPLEX (MHC)# MHC is a gene cluster of various loci grouped together on a single locus.# The MHC of humans, or the HLA complex, is located on the short arm of chromosome 6 approximately 32 CM from the centromere.# The loci of the HLA complex may be divided into three classes: Class I, Class II, and Class III.# The products of Class I and Class II genes play an important role in the communication between cells. These MHC molecules are surface proteins which present antigenic peptides to T lymphocytes.