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What is Which of the following is seen in Churg-Strauss syndrome? and explain in detail?
Churg-Strauss syndrome is a small vessel vasculitis. The acute presentation includes skin lesions, eosinophilia and asymmetric mononeuritis multiplex. There can be a prodromal period lasting many years in which the patient can have allergic rhinitis, nasal polyposis and asthma. Treatment is by high dose steroids and cyclophosphamide. Maintenance therapy is by low dose steroids, azathioprine, methotrexate and mycophenolate mofetil. Ref: Davidson's Principles and Practice of Medicine, 22nd edition, p1118