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What is A 36-yrs-old woman presents with increased trouble swallowing. Physical examination finds hypeension and sclerodactyly. Lab tests find Anti- Scl- 70. Which of the following biopsies is most characteristic of this disorder? and explain in detail?
A skin biopsy that reveals dermal fibrosis with an absence of adnexal structures * The combination of trouble swallowing, hypeension, and sclerosis of the skin should raise the possibility of progressive systemic sclerosis (scleroderma), a multisystem disease that involves the cardiovascular, * a peripheral nerve biopsy that reveals rare acid-fast bacteria is diagnostic of leprosy; and a temporal aery biopsy that reveals fragmentation of the internal elastic lamina is characteristic of ternporal aeritis.