You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A girl at 16 years of age presents with primary amenorrhea. On examination breast development is normal , axillary and pubic hair are present. Vaginal examination reveals an absent vaginal opening. Ultrasound suggests normal ovaries with absent uterus. Most probable diagnosis is? and explain in detail?
MRKH Androgen insensitivity syndrome Genotype XX XY Gonad Ovaries Testes Breast development Normal Normal Pubic and axillary hair Normal Absent (insensitivity to testosterone) Vagina Shallow and blind Shallow and blind Uterus Absent Absent Vulva Normal Normal Sr Androgen levels 20-80 ng/dl 200-800 ng/dl TURNERS IS XO - Near normal female phenotype and streak ovaries. This is the most common type of gonadal dysgenesis.