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What is Which of the following drug is used to decrease postpaum hemorrhage in a normotensive woman? and explain in detail?
Ergot alkaloids markedly increase the motor activity of the uterus. They are used to prevent or treat postpaum hemorrhage in normotensive women. In this setting, the preferred ergot alkaloids are ergonovine (ergotrate) or its methyl analog methylergonovine (methergine). They are administered intramuscularly or intravenously, exhibit rapid onsets of action (2-3 minutes intramuscularly, Ref: Schimmer B.P., Parker K.L. (2011). Chapter 66. Contraception and Pharmacotherapy of Obstetrical and Gynecological Disorders. In L.L. Brunton, B.A. Chabner, B.C. Knollmann (Eds), Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e.