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What is Which of the following regarding sickle cell disease is false? and explain in detail?
In HbS, the nonpolar amino acid valine has replaced the polar surface residue Glu6 of the β subunit, generating a hydrophobic “sticky patch” on the surface of the β subunit of both oxyHbS and deoxyHbS.
Ref: Harper’s illustrated biochemistry. 30th edition page no: 56