You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Virus causing cervical cancer in the ectocervix - and explain in detail?
Ans. is 'a' i.e., HPV 16 Carcinoma cervixo The m/c etiological factor associated with cancer cervix is Human Papillomavirus (HPV).o HPV is epitheliotropic.o High-risk HPVInclude 16, 18, 31, 33, 35, 39. 45, 52, 56, 58, 59, 68.o Low-risk HPV associated with genital warts are subtype 6 and 11.o Almost 80% women are infected by HPV at some point in their lives.o HPV DNA detection is used along with pap smear as a screening procedure:o (PCR) polymerase chain reaction or Southern blot or hybrid capture technique is used for HPV DN A detection.Factors predisposing to CIN/Ca Cervixo Human papilloma virus infection (most important)o Factors increasing the risk of sexually transmitted infections :Coitus before 18 years of ageMultiple sex partnersMultiparityPoor personal hygienePoor socioeconomic statuso Smokingo Immunosuppressed individualso Women on OCP or progesterone therapy for a long time, are predisposed to adenocarcinoma of the endocervix.o In utero exposure to diethylstilbestrol (DES).