You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is The uricosuric agent used for acute gout in a chronic renal failure patient is: and explain in detail?
Uricosuric agents such as probenecid can be used in patients with good renal function who underexcrete uric acid. Probenecid is generally not effective in patients with serum creatinine levels >177 mol/L (2 mg/dL). These patients may require allopurinol or benzbromarone. Benzbromarone is another uricosuric drug that is more effective in patients with renal failure. Ref: Schumacher H.R., Chen L.X. (2012). Chapter 333. Gout and Other Crystal-Associated Ahropathies. In D.L. Longo, A.S. Fauci, D.L. Kasper, S.L. Hauser, J.L. Jameson, J. Loscalzo (Eds), Harrison's Principles of Internal Medicine, 18e.