You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A 45 Yr old woman presents with a hard and mobile lump in the breast. Next investigation is and explain in detail?
First investigation : Mammography First investigation for tissue sampling : FNAC Best and diagnostic investigation : Biopsy Investigations in CA Breast Mammography - Initial investigation for symptomatic breast in women>35 years and for screening. Investigation of choice for microcalcification Ultrasound- Initial investigation for palpable lesions in women < 35 years. Not useful in screening MRI- Indicated in scarred breast, implants and borderline lesions for breast conservation. Investigation of choice for implant related complication. Gold standard for imaging breast in females with implants. PET scan- Investigation of choice for detecting recurrences in scarred breast. Useful multifocal disease and in helping detect axillary movement Ref:Sabiston 20th edition Pg no : 826- 827