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What is Amoxicillin + clavulanic acid is active against the following organisms EXCEPT : and explain in detail?
Staphylococcus aureus develops resistance to methicillin by acquiring altered penicillin-binding proteins that have low affinity. No Beta-lactam antibiotic is effective against MRSA.
Clavulanic acid is an inhibitor of β-lactamase. It can restore the sensitivity of penicillins against the organisms who have developed penicillinases.