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What is lxabepilone is and explain in detail?
Ans. is 'b' i.e., Antineoplastic Ixabepilone o Ixabepilone also known as azaepothilone B. o It has been approved by FDA for the treatment of aggressive metastatic or locally advanced breast cancer which is not responding to standard chemotherapy o It is given in combination with capecitabine. o It has also been investigated for use in treatment of non-Hodgkin's lymphoma. o It acts by binding to tubulin and promoting microtubule stabilization (like taxanes) thereby acting on M phase of cell cycle.