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What is Sweaty feet odour in body fluids occur due to deficiency of and explain in detail?
The impaired enzyme in isovaleric acidemia is isovaleryl-CoA dehydrogenase. Vomiting, acidosis and coma follow ingestion of excess protein. Accumulated isovaleryl-CoA is hydrolyzed to isovalerate and excreted. Characteristic odor of sweaty feet is present.
Harper's Illustrated Biochemistry 30 th edition page no 309