You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A patient after giving inhalational anaestheia developed fulminant hepatitis, patient was exposed to same drug previously. Which is the drug? and explain in detail?
Ans. is 'a' i.e., Halothane Halothane It is a volatile liquid with sweet odour, nonirritating and noninflammable. It is a potent anaesthetic with poor analgesic and muscle relaxant propeies. Halothane causes direct depression of myocardial contractility by reducing intracellular Ca+2. It causes fall in BP and CO. Hea rate decreases due to vagal stimulation. It tends to sensitize the hea to arrhythmogenic action of adrenaline --* contraindicated in pheochromocytoma. It causes greater depression of respiration and ventilation perfusion mismatch. It dilates the bronchi --> inhalation agent of choice in asthmatics (intravaneous anaesthetic of choice in asthmatics is ketamine). It is a hepatotoxic drug and can also cause malignant hypehermia (Succinylcholine accentuate it). Recovery is smooth and reasonably quick. It causes postanaesthetic shivering and chills. It inhibits intestinal and uterine contractions --> agent of choice for assisting external or internal version during late pregnancy. Because its uterine relaxant action it is contraindicated during labour. It is paicularly suitable for induction and maintenance in children and as maintenance anaesthetic in adults.