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What is Most important prognostic factor for breast carcinoma is: and explain in detail?
Ans. (b) Lymph node involvementPrognosis related to lymph node status:* Overall the best prognostic factor for ca breast - disease free survival and overall survival is axillary lymph node status.* But if the question has the choice of staging, then it must be opted because it includes lymph node status & metastasis also.* But the question if asked about the prognosis in metastatic: ca breast- the best option is ER or PR status because the further prognosis and survival in metastatic patients is based on their response to hormone therapy.* The patients with ER positive and more with PR positive will respond well with hormone therapy and have a prolonged survival