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What is All of the following statements about Lipoprotein Lipase are true, Except : and explain in detail?
D i.e. Does not require CII as cofactorIn the capillaries of adipose, hea, skeletal muscle and lactating mammary tissuesQ, lipoprotein lipase is activated by apo CII aproprotein of chylomicron and VLDLQ and the enzyme degrades the triacyl glycerol to yield fatty acid and glycerol.Apo CII is essential for activation whereas apo All and C III inhibits the lipoprotein lipase enzymeQ. So the patients with a deficient lipoprotein lipase or apo CII (i.e. Type I hyperlipoproteinemia or Familial lipoprotein lipase deficiency) show a very high (> 1000 mg/dl) accumulation of chylomicrons containing triacyl glycerol in plasma i.e. hyperiacylglycerolemia even in fasting stateQ.