You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Continuous GnRH is useful in all except: and explain in detail?
Ans. (C) Male infertility(Ref: Goodman Gilman 13th E/P781)GnRH agonists can be used by pulsatile and non-pulsatile or continuous dosing.By pulsatile dosing they increase release of LH/FSH and cause ovulation, spermatogenesis and increase synthesis estrogen and testosterone. Hence used for treatment of anovulation, oligospermia (male infertility), delayed puberty and sexual infantilism.By continuous dosing, they decrease synthesis of estrogen and testosterone. Hence used for treatment of estrogen and testosterone dependent conditions like ER positive breast cancer, endometriosis, uterine fibroids and prostate cancer.