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What is Graft Versus host reaction is mediated by and explain in detail?
In GVHD, the donated bone marrow or peripheral blood stem cells view the recipient's body as foreign. The donated T cells present in the graft, attack the tissues of the transplant recipient after perceiving host tissues as antigenically foreign. There are two forms of GVHD: Acute graft versus host disease (aGvHD). Chronic graft versus host disease (cGvHD). Ref: Ananthanarayana textbook of Microbiology 9th edition Pgno : 186