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What is Moderate to high titres of anti-DNA and anti-Smith antibodies are almost pathognomonic of: and explain in detail?
Laboratory Findings
Antinuclear antibodies are frequently found in patients with SLE and can be used to indicate a systemic involvement, but patients with other rheumatologic diseases, such as Sjögren’s syndrome and rheumatoid arthritis, may be positive as well. Moderate to high titers of anti-DNA and anti-Smith antibodies are almost pathognomonic of SLE.