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What is IL-2 is secreted by - and explain in detail?
Option 1 IL-2 (Previously called T-cell growth factor) is a protein produced mainly by helper T 1 cells. It is a major T-cell growth factor. It stimulates both helper and cytotoxic T cells to grow. It also promotes the growth of B cells and can activate natural killer (NK) cells and monocytes. IL-2 acts on T cells in an autocrine fashion. Activation of T cells results in expression of IL-2R and the production of IL-2. Option 2, 3, 4 IL-1: Produced by all nucleatedcells (Mainly by APCs such asMacrophages, monocytesdendritic cell, B-cells andendothelial cell). IL-6: TH 2 cells, macrophages IL-8: Macrophages, endothelial cells IL-12: Macrophages