You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is After digestion by restriction endonucleases DNA bands can re-joined by which of the following substance? and explain in detail?
DNA ligase is used to join the DNA bands formed after digestion by restriction endonuclease. DNA gyrase: Its a special type of topoisomerase, has the unusual propey of being able to introduce negative supercoils into resting DNA. This facilitates the future replication of DNA because the negative supercoils neutralise the positive supercoils introduced during opening of the double helix.