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What is Call exner bodies are found in: and explain in detail?
Ans: A (Granulosa cell tumour)Explanation:GRANULOSA CELL TUMOURAccounts for 2% of ovarian neoplasmsOriginates from rest of Primitive granulosa cellsMost common ovarian stromal tumour2% bilateral, slow growingSolid/cvsticCut section--yellow/orange due to lipid contentHistopath- Cells polygonal or round with granular eosinophilic cytoplasm with ill defined borders with coffee bean nuclei- Granulosa cells are arranged in small clusters around a central cavity called call exner bodiesTumour marker--InhibinUnapposed estrogen secretion- Endometrial hyperplasia- Endometrial caC/F--due to hyperestrogenismPrecocious pubertyAUBPostmenopausal bleedingMay rupture and cause acute abdomenTreatment--Laparotomy and surgical staging. Unilateral salpingooopherectomyChemotherapyVAC Regimen BEP Regimen