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What is All are TNF-a antagonists used in rheumatoid ahritis except: and explain in detail?
TNF -ALPHA INHIBITORS 1.Etanercept: chimeric protein and neutralizes both TNF alpha and TNF beta. Can be used along with methotrexate in rheumatoid ahritis. Also used in ankylosing spondylosis, juvenile ahritis, and plaque psoriasis 2.Infliximab: Monoclonal antibody against TNF alpha.used in refractory rheumatoid ahritis, Crohn's disease, ulcerative colitis, and psoriasis. 3.Adalimumab:fully human recombinant antibody anti TNF alpha. It is less antigenic.use same as infliximab ESSENTIAL OF MEDICAL PHARMACOLOGY: SEVENTH EDITION, KD TRIPATHI, Page 883,884