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What is Select the most suitable antiarrhythmic drug for counteracting ventricular extrasystoles due to digoxin toxicity and explain in detail?
Digitalis Toxicity:- Toxicity of digitalis is high, margin of safety is low (therapeutic index 1.5-3). Higher cardiac moality has been repoed among patients with steady-state plasma digoxin levels > 1.1 ng/ml but still within the therapeutic range during maintenance therapy. Manifestations and treatment of toxicity For ventricular arrhythmias:- Lidocaine i.v. repeated as required is the drug of choice. It suppresses the excessive automaticity, but does not accentuate A-V block. Quinidine, procainamide and propafenone are contraindicated. Ref:- kd tripathi; pg num:-516