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What is A resident sustained a needlestick injury while sampling blood of a patient who is HIV positive. A decision is taken to offer him post-exposure prophylaxis. Which one of the following regimens would be the best recommendation? and explain in detail?
Recommended post-exposure prophylaxis is a combination of Lopinavir+Ritonavir for 4 weeks. NACO recommended PEP regimen : Dosages of the drugs for PEP for adults Recommendation for PEP Duration Tenofovir (TDF) 300 mg + Lamivudine(3TC) 300 mg (FDC) One tab Immediately within 2 hours of accidental exposure,from next day one tab once OD, 4 weeks Lopinavir (200 mg) + Ritonavir (50 mg) (FDC) Two Tab Immediately within 2 hours of accidental exposure,from next day two-tab BD, 4 weeks Reference: Ananthanarayan and Paniker&;s Textbook of Microbiology Tenth edition