You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A five year old girl is brought to a pediatrician because she is developing breasts. Physical examination shows large hyperpigmented macules with irregular margins on one side of her back. Which of the following bony abnormalities would most be likely associated with these symptoms? and explain in detail?
McCune-Albright syndrome is the combination of precocious sexual development, irregularly shaped ("coast of Maine") pigmented skin macules, and polyostotic fibrous dysplasia. The latter condition is characterized by local bony defects containing unmineralised whorls of connective tissue. Renal osteodystrophy refers to a constellation of bony changes occurring in the context of chronic renal failure. Features may include those of osteitis fibrosa cystica (marrow fibrosis, bony resorption and cyst formation within the marrow cavity) and osteomalacia. Osteomalacia results from vitamin D deficiency in adults, and is characterized by a generalized thinning of bony spicules. Osteopetrosis is characterized by excessive bony deposition that can obliterate marrow , causing anemia. Ref: Bauman D. (2013). Chapter 37. Pediatric & Adolescent Gynecology. In A.H. DeCherney, L. Nathan, N. Laufer, A.S. Roman (Eds), CURRENT Diagnosis & Treatment: Obstetrics & Gynecology, 11e.