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What is Increased alanine during prolonged fasting represents: and explain in detail?
Ans. A. Increased breakdown of muscle proteinsDuring prolonged fasting, there is increased gluconeogenesis. Alanine provided by muscle is one of the substrates for gluconeogenesis.This is called Glucose Alanine Cycle or Cahill Cycle.So plasma level of Alanine rises in prolonged starvation.Remember:In prolonged fasting plasma level of Alanine rises.In hyperammonemia plasma level of Glutamine rises.