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What is All are true about Lesch-Nyhan syndrome except: and explain in detail?
Answer- D. Occur equally in both sexesA complete deficiency of HP, the Lesch-Nyhan syndrome, is characterized by hyperuricemia, self-mutilative behavior, choreoathetosis, spasticity, and mental retardation.This is a rare X-linked disorder of purine metabolism that results from HP deficiency.The hyperuricemia results from urate overproduction and can cause uric acid crystalluria, nephrolithiasis, obstructive uropathy, and gouty ahritis.Affects Males only.Etiology- hereditaryTreatment-Allopurinol