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What is Drug of choice for pneumocystis carinii is and explain in detail?
The treatment of choice for PCP is trimethoprim-sulfamethoxazole (TMP-SMX), given either IV or PO for 14-21 days .TMP-SMX, which interferes with the organism's folate metabolism, is at least as effective as alternative agents and is better tolerated. Ref Harrison 19th edition pg 1019 Davidson edition23rd pg 587