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What is CYP–450 inducers are: and explain in detail?
- P450 inducers

   Phenobarbitone
   Rifampicin
   Phenytoin
   Chloral hydrate
   Griseofulvin
   Phenylbutazone
   DDT
   Chronic alcohol ingestion

-          Cimetidine and Ketoconazole inhibits metabolizing enzymes.