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What is All of the following are true about Graves disease, except:- and explain in detail?
Graves disease is an autoimmune disorder which is 10 times most common in females presenting in 20-40yrs of age. It causes hypehyroidism d/t overstimulation of TSH receptors by TSIg. Its risk is increased in monozygotic twins. It is associated with ceain genes like HLA-DR3 , HLA-B8. Also associated with other autoimmune disorders like SLE, Type-1 DM, Pernicious anemia, Addison's disease etc. Non-thyroid manifestations like eye & skin involvement can be seen.