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What is What is the chance of HIV infection after needle prick injury? and explain in detail?
Needle prick injury: HIV transmission following skin puncture from a contaminated needle is 0.3 % and a mucous membrane exposure is 0.09%. The seroconversion rate for HIV is 1:300, or 0.3% from a hollow-bore needle stick injury. Antiretroviral drugs as postexposure prophylaxis decreases the risk of infection. Must know: In Hepatitis B, the seroconversion ranges from 23 to 62%, with higher rates associated with patients who are HBeAg positive, as compared to HBeAG negative. The seroconversion rate for Hepatitis C is 1.8%. For Hepatitis C no prophylactic treatment is available. HBV post exposure prophlylaxis with hepatitis B immunoglobulin and initiation of Hep B vaccine is 90%effective. Ref: Harrison's Principles of internal medicine, 16th edition, page 1081.