You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is All of the following are minor criteria for multiple Myeloma, Except and explain in detail?
Answer is C (Plasmacytoma on tissue biopsy) Plasmacytoma or tissue biopsy is a major criterion for diagnosis of multiple myeloma (and not a minor criterion)