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What is Treatment of choice for sputum positive pulmonary tuberculosis detected in 1st trimester of pregnancy? and explain in detail?
Ans. is 'b' i.e., Sta cat. I immediately Treatment of TB during pregnancy o Active tuberculosis in pregnancy should be treated. o Treatment should be initiated as soon as the diagnosis is made because maternal tuberculosis is associated with spontaneous aboion, perinatal moality, small for gestational age and LBW. o First line drugs can be safely used in pregnancy except streptomycin which is contraindicated because of its association with fetal ototoxicity. Isonizide, Rifampicin, pyrizinamdie and ethambutol are safe to use. o Second line drugs such as fluoroquinolenes, ethionamide and protionamide are teratogenic and should not be used.