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What is A patient presents with zo11inger-Ellison syndrome due to gastrinoma. He has two bleeding ulcers and diarrhoea. A drug that irreversibly inhibits the H+/K+ ATPase in gastric parietal cells is: and explain in detail?
that react covalently with SH groups of the H+K+ATP ase enzyme and inactivate it irreversibly ESSENTIALS OF MEDICAL PHARMACOLOGY SEVENTH EDITION KD TRIPATHI PG NO 651