You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is In the placenta, maternal blood comes in direct contact with: and explain in detail?
The syncytiotrophoblast forms the surface layer of the chorionic villi and is bathed by maternal blood flowing through the intervillous space. The syncytiotrophoblast is a product of division infusion of cells in the underlying cytotrophoblast. Fetal capillaries course through the fetal connective tissue that forms the core of all orders of villi, and thus have no contact with maternal blood when placental structure is intact. As the syncytiotrophoblast is a derivative of the embryonic trophoblast layer, it is incorrect to state that maternal blood has no contact with fetally derived cells. Ref: Cunningham F.G., Leveno K.J., Bloom S.L., Hauth J.C., Rouse D.J., Spong C.Y. (2010). Chapter 3. Implantation, Embryogenesis, and Placental Development. In F.G. Cunningham, K.J. Leveno, S.L. Bloom, J.C. Hauth, D.J. Rouse, C.Y. Spong (Eds), Williams Obstetrics, 23e.