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What is All of the following statements about treatment of migraine are true, except and explain in detail?
Ans. is 'd' i.e., Sumatriptan is used for chronic migraine Triptans Triptans are selective agonists at 5HT 1B/ID receptors a variety of triptans are now available for the management of acute migraine Triptans Fast acting Rizatriptan Eletriptan Sumatriptan Z olmitriptan Almotriptan (relatively slower) Slow acting/ Better tolerability naratriptan Frovatriptan These agents have longer half life Rizatriptan and eletriptan are the most efficacious of the triptans currently available in the United states ? Efficacy appears to be related more to 1 max (time to peak plasma concentration) than to the potency, half life or bioavailability