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What is Which of the following is not a myeloproliferative neoplasm? and explain in detail?
Juvenile myelomonocytic leukemia is not included in the category of MPNs (myeloproliferative neoplasms) in WHO classification Examples of myeloproliferative neoplasms: Chronic myeloid leukemia Polycythemia vera Primary myelofibrosis Essential thrombocythemia Chronic eosinophilic leukemia Activating JAK2 mutations are seen in: Nearly all cases of polycythemia vera Approx. 50% of cases of primary myelofibrosis and essential thrombocythemia BCR-ABL1 translocation seen in CML