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What is Bulls eye retinopathy is seen in toxicity of: and explain in detail?
Ref: Parson's 21st edition Diseases of the Eye page no:358Kanski: Clinical Ophthalmology; 7th edition, pg no 864Explanation:Chloroquine is a melanotropic drugIt is excreted very slowly from the body & get accumulated in melanin containing structures like RPE & choroidHydroxychloroquine - Less toxicMaximum dosage - Chloroquine - 6mg/kg/dayHydroxychloroquine - 4.5mg/kg/dayOther ocular side effects:vortex keratopathy - reversibleAnterior capsular cataract,Optic neuropathyOther causes of Bull's Eye MaeulopathyCone dystrophyCone rod dystrophyInverse retinitis pigmentosaStargardt 's disease