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What is The maximal increase of free histamine content occurs within how much time after injury and explain in detail?
The maximal increase of free histamine content occurs within 20 -30 minutes after injury. Biochemical timing of injury: It depends upon the measurement of histamine and serotonin contents of the injured tissue. Serotonin becomes maximum in about 10 min and histamine in 20-30 min after wounding. If the stroma is damaged ,tissue cathepsins increase immediately, can be demonstrated within 5 to 10 minutes Postmoem wounds do not show any increase.