You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which of the following statements about Hepatitis C is TRUE? and explain in detail?
Progression to cirrhosis or hepatocellular carcinoma is a major cause of morbidity and the most frequent indication of liver transplantation in adults in united states. Ref: Kliegman, Behrman, Jenson, Stanton (2008), "Nelson Textbook of Pediatrics", Chapter 355, "Viral Hepatitis", Volume 2, Page 1687; Harrison's Principles of Internal Medicine, 17th Edition, Pages 1939, 1963, 1984; Current Gastroenterology, 2nd Edition, Page 556