You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Histologic examination of the lesion in stomach reveal fat-laden cells, likely cause is - and explain in detail?
Lipid-laden macrophages (foam cells) are seen in xanthomatosis of the stomach.

Xanthomatosis of stomach

It is characterized by a collection of lipid-laden macrophages (foam cells), forming plaques or nodules.
Gastric xanthomatosis is more common in patients with : -

1. Gastritis
2. Gastric ulcer 
3. Deudenogastric reflux after gastric surgery.