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What is Anesthetic agent contraindicated in raised ICT is? and explain in detail?
Ans. is 'a' i.e., Ketamine * Ketamine increases cerebral metabolic rate, cerebral blood flow and intracranial tension.Neurophysiology and anaesthesiaA. Intravenous inducing anaesthetics# All intravenous inducing agents except for ketamine (i.e., etomidate, thiopentone, methohexitone and propofol) decrease cerebral metabolic rate, cerebral blood flow and intracranial tension. Maximum decrease in cerebral blood flow and cerebral protection is caused by thiopentone - IV agent of choice for neurosurgery.B. Inhalational agents# All inhalational agents: -i) Increase intracranial tension and cerebral blood flow.ii) Decrease cerebral metabolic rate - There by provide cerebroprotection.iii) Amongst inhalational agents, isoflurane provides maximum cerebroprotection, therefore it is the inhalational agent of choice for neurosurgery.C. Lidocaine# Lidocaine decreases ICT, Cerebral blood flow and metabolic rate.