You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which of the following is dihydroorotate dehydrogenase inhibitor? and explain in detail?
Ans. is 'b' i.e., Leflunomide Important DMARDsMechanism of action* MethotrexateDihydrofolate reductase inhibitor* SulfasalazineSulfapyridine moiety suppresses the generation of superoxide radicals and cytokine production* LeflunomideIs rapidly converted in the body to an active metabolite which inhibits dihydroorotate dehydrogenase.* Hydroxychloroquine* Reduce monocyte IL-1, consequently inhibiting B-cells* Interferes with antigen processing* Stabilizes lysosome and free radical scavenging.