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What is schultz dale phenomenon the following is true statements : and explain in detail?
Schultz-Dale reaction A method for demonstrating anaphylactic hypersensitivity outside the body by suspending an excised intestinal loop or uterine strip from a sensitized animal in an oxygenated, physiological salt solution; addition of the proper allergen causes contraction of the smooth muscle. TYPE I Hypersensitivity * Type I hypersensitivity -- immediate or anaphylactic hypersensitivity * Immediate hypersensitivity is mediated by IgE * The primary cellular component in this hypersensitivity is the mast cell or basophil * The reaction is amplified by neutrophils and eosinophils ref /; anantharayana 9th ed