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What is Oxidative or Respiratory burst phenomenon? and explain in detail?
Activation of NADPH oxidase is associated with a sharp increase in O2 uptake and metabolism in the neutrophil (the respiratory burst) and generation of O2- by the following reaction: NADPH + H++ 2O2+ - NADP++ 2H++ 2O2- Reference: Ganong's Review of Medical Physiology; 25th edition; Page no: 68