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What is Adenosine deaminase deficiency is seen in the following - and explain in detail?
Severe combined immunodeficiencies include syndrome with severe deficiency of both humoral and cell mediated response. Adenosine deaminase deficiency is a distinct pattern of SCID. - ADA catalyses the conversion of adenosine to inosine in the purine metabolic pathway. This condition is associated with chondrocyte abnormalities. Reference : Anathanarayan & paniker's 9th edition, pg no:174,175 <\p>