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What is Contraction of endothelial cytoskeleton in acute inflammation leads to and explain in detail?
Increased vascular permeability is the hallmark of acute inflammation.

Remember

Early transient increase is due to = Endothelial cell contraction
Delayed transient increase in permeability is due to = Direct endothelial injury
Delayed permanent increase Endothelial cell retraction is due to = endothelial cell damage