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What is JAK-STAT kinase receptors is associated with ? and explain in detail?
Ans. is'd'i.e., Nuclear transcriptionJAK-STAT-Kinase binding receptors:These receptors differ in not having intracellular enzymatic action on receptor itself. Agonist binding induces interaction of these receptors with free intracellular tyrosine kinase - Janus kinase (JAK).jAK phosphorylates activators of transcription (STAT), which then regulate the nucleus transcription resulting in a biological response.Examples -+ Growth hormone, Prolactin,