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What is Mutation seen in sickle cell anemia: and explain in detail?
Sickle-cell anemia Due to a single base alteration Point mutation Glutamate at the 6th position of b-chain of haemoglobin is replaced by Valine. UCA (serine) UCU (Serine) CCA (Proline) UAA (Stop codon) Silent mutation Mis-sense mutation Non sense Mutation