You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which NSAID can cause hyperuricemia? and explain in detail?
ASPIRIN can cause hyperuricemia depending on dose used. At low doses :1-2g/day -decrease uricacid excretion and hence cause hyperuricemia. It also blocks the effects of probencid and other uricosuric drugs. Intermediate doses:2-3g/day-No effect Large doses:>5g/day-uricosuric 1st most commonly used NSAID in hyperurecemia ahritis (gout) is NAPROXONE 2nd most commonly used is IBUPROFEN ref : maheswari th ed