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What is Transamination of aspaate leads directly to -------- of the citric acid cycle and explain in detail?
Transamination of aspaate leads directly to the formation of oxaloacetate, and a variety of compounds that are metabolized to yield propionyl CoA, which can be carboxylated and isomerized to succinyl CoA are also impoant anaplerotic substrates.Ref: Harper&;s Biochemistry; 30th edition; Chapter 16; The Citric Acid Cycle: The Central Pathway of Carbohydrate, Lipid & Amino Acid Metabolism