You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A 69-year-old woman presents to the clinic with memory difficulty. The patient's daughter is concerned that her mother is having difficulty doing her finances, such as paying bills. Memory impairment testing reveals the poor ability to generate lists of words or copy diagrams (intersecting pentagons). Her remaining physical examination is normal. Which of the following anatomic findings is most likely with her condition? and explain in detail?
Alzheimer disease (AD) can be quite diffuse, but there is particular involvement of the medial temporal lobes and cortical association areas. The atrophy of the hippocampus is particularly marked. Microscopic examination reveals neurofibrillary tangles and amyloid plaques. Hemiplegia is not a feature of AD and suggests more vascular disease and vascular dementia. The cranial nerves are not involved in AD.