You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A reversible change occurring in which a mature cell type is replaced by another mature cell, is called: and explain in detail?
Ref: Robbin's Pathology, 9th ed. pg. 37* Metaplasia is an adaptive response of a cell in response to stress.* It is a reversible change in which a differentiated (mature) cell type is replaced by another differentiated cell type.* It can be of two types:# Epithelial metaplasia* Squamous metaplasia: MC seen in respiratory tract (in response to smoking) where columnar epithelium is replaced by squamous epithelium.* Glandular metaplasia: Metaplasia of squamous epithelium into columnar (glandular) epithelium. Example Barret's esophagus (metaplasia of stratified squamous epithelium of esophagus is replaced by intestinal-like columnar cells).# Connective tissue metaplasia:* One type of connective tissue is replaced by another.* Example: Myositis ossificans.* Hypertrophy: Increased cell size in response to increase in workload. It occurs in tissues incapable of cell division.* Hyperplasia: increase in cell number in response to growth factors or hormones.* Atrophy: Decrease in cell and organ size as a result of disuse or decreased nutrient supply.