You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which drug is not acetylated ? and explain in detail?
Metoclopromide Acetylation is a phase II metabolic reaction Phase II reactions serves to attach a conjugate to the drug molecule. After the phase II reactions all drugs becomes water soluble, so that they can be readily eliminated from the body. Phase II reactions includes - Glucuronidation - Acetylation - Methylation - Sulfation - Glycine conjugation Acetylation Drugs having amino or hydrazine resides are conjugated with the help of acetyl coenzyme A. Examples are : S - Sulfonamides (Dapsone) H- Hydralazine I - Isoniazid P - PAS Acetylation is a genetically mediated condition. Multiple genes control the acetyl transferases and the rate of acetylation shows genetic polymorphism