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What is Drug implicated for prolongation of QT interval in a premature baby is - and explain in detail?
Ans. is 'c' i.e., Cisapride Cisapride inhibits the delayed rectifying IC- channels in hea and can cause prolongation of QT interval. o Drugs inhibiting CYP3A4 enzyme can precipitate Torsaes DePointes, Caused by cisapride eg; clarithromycin, erythromycin, cyclosporine, fluconazole, itraconazole, ketoconazole, Nefazodone, Ritonavir, Fluvoxamine.