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What is Methotrexate toxicity is treated by? and explain in detail?
Ans. is 'a' i.e., Folinic acid Folinic acid rescue o Where it is desired to maximise the effect of methotrexate a potentially fatal dose is given and is followed 24 h later by a dose of folinic acid to terminate its action. o High concentrations of methotrexate are obtained and bone marrow cells recover better than the tumor cells and some degree of useful selectivity is achieved