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What is Which of the following has a Ketogenic effect on liver? and explain in detail?
Physiological Actions of GlucagonGlucagon is the most potent hyperglycemic hormone. It is anti-insulin in nature. Therefore, the net effect is decided by the insulin-glucagon ratio (Fig.24.8).Glucagon is mainly glycogenolytic. The active form of glycogen phosphorylase has formed under the influence of glucagon. Liver is the primary target for the glycogenolytic effect of glucagon.It depresses glycogen synthesis.Gluconeogenesis is ored by glucagon by inducing enzymes like PEPCK, glucose-6-phosphatase, and fructose-1,6-bisphosphatase.Glucagon increases plasma free fatty acid level. In adipose tissue glucagon ors beta-oxidation, as it activates carnitine acyltransferase. The mitochondrial acetyl CoA level increasesKetogenesis is ored.Ref: DM Vasudevan - Textbook of Biochemistry, 6th edition, page no: 284-285