You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Gas gangrene is due to and explain in detail?
The alpha-toxin is produced by all types of Clostridium perfringens and most abundantly by type A strains. This is the most impoant toxin biologically and is responsible for the profound toxemia of gas gangrene. It is lethal, dermonecrotic and hemolytic. It is phospholipids which, in the presence of calcium and magnesium ions, splits lecithin into phosphorylcholine and diglyceride. Reference: Textbook of Microbiology; Anathanarayan and paniker's; 10th edition; Page no: 259