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What is Increased formation of ketone bodies during fasting is a result of: and explain in detail?
Free fatty acids bound to albumin are increased as a result of an increased activity of Hormone sensitive lipase in adipose tissue as this enzyme breaks TG into glycerol & fatty acids. These fatty acids are taken up by liver. b-oxidation of these fatty acids in liver provides the acetyl CoA for ketogenesis. Hepatic ketogenesis is also stimulated by elevated levels of glucagon during fasting.