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What is Sirolimus is more likely to cause ____________ more than cyclosporine: and explain in detail?
* Sirolimus (rapamycin) results in suppression of bone marrow,mainly causing thrombocytopenia.other adverse effects are diarrhoea,liver damage and pneumonitis. * Cyclosporine and tacrolimus cause nephrotoxicity,hepatotoxicity,neurotoxicity as an adverse effect.