You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is In cirrhosis in space of disse which type of collagen accumulates - and explain in detail?
Harshmohan textbook of pathology 7th edition. fibrosis in the liver mobiles may be poal- central, poal poal, or both. The mechanism of fibrosis is by increased synthesis of type1 and type3 collagen in the space of disse. There is proliferation of fat storing Ito, uderlyig the sinus epithelium, which are transformed into myofibroblast and fibro cells..