You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is In severe cases Lucio's phenomenon is treated with: and explain in detail?
Lucio phenomenon - Type of lepra reaction seen in patients of Lucio leprosy where lesions are ulceronecrotic over lower extremities Do not respond to conventional treatment (Thalidomide) So in Severe cases exchange transfusion is done