You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Activation of which of the following hormone's receptors produces E.Coli induced diarrhoea? and explain in detail?
Guanylin is a gastrointestinal polypeptide that binds to guanylyl cyclase. It is secreted by cells of the intestinal mucosa. Stimulation of guanylyl cyclase increases the concentration of intracellular cyclic 3',5'-guanosine monophosphate (cGMP), and this in turn causes increased secretion of Cl- into the intestinal lumen. The heat-stable enterotoxin of ceain diarrhea-producing strains of Escherichia coli has a structure very similar to guanylin and activates guanylin receptors in the intestine.