You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Treatment of choice for pleomorphic adenoma? and explain in detail?
Ans. c (Excision of tumor [surgical removal) (Ref. Bailey and Love Surgery 25th/pg. 762)PLEOMORPHIC ADENOMA# Initially described as a 'mixed' salivary gland tumor# Accounts for 75% of parotid and 50% submandibular tumors# Believed to have both epithelial and mesothelial elements# Now appears to arise from ductal myoepithelial cells# Slight female predominance known# May undergo malignant change but risk is small# Little is known about the origins of these neoplasms except that radiation exposure increases the risk. Equally uncertain is the histogenesis of the various components. A currently popular view is that all neoplastic elements, including those that appear mesenchymal, are of either myoepithelial or ductal reserve cell origin (hence the designation pleomorphic adenoma).# Requires excision with 5-10 mm margin as local implantation of cells can lead to recurrence.# Treatment of choice for pleomorphic adenoma is superficial parotidectomy but, if the deep lobe of parotid is involved -Total parotidectomy is done.