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What is Oxygen dissociation curve shifts to left in all except: and explain in detail?
When the O2 affinity for Hb is increased, the dissociation curve shifts to the left. O2 has less affinity for Hb which is in "T-state". When Hb is snapped into "R-state", O2 affinity for it increases. Increased affinity of O2 for Hb/shift to the left Decreased H+/alkalosis Decreased PCO2 Decreased temperature Decreased 2,3-DPG HbF CO poisoning Stored blood (2,3-DPG decreases) NO & H2S (bind to Hb; snap it into "R-state")