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What is Drug of choice for withdrawal syndrome in a neonate due to maternal opiate addiction is- and explain in detail?
Ans. is 'a' i.e., Methadone * Drug withdrawal is a self-limiting process.* However, withdrawal from sedative-hypnotic drugs or narcotics can be lifethreatening.* Indications for drug treatment include seizures, poor feeding, diarrhea, excessive vomiting, inability to sleep, and fever.Management of Opiate withdrawal* Care in a quiet environment with reduction of external stimuli and swaddling.* Pharmacologic treatment of heroin and methadone withdrawal requires opiate replacement during the 1st wk or 2 of life.* Methadone is the drug of choice, but oral or sublingual buprenorphine is an alternate approach.* Adjunct treatment with phenobarbital or clonidine is rarely necessary.* Methadone withdrawal may require larger amounts of medication for longer periods to control clinical manifestations than are needed for heroin withdrawal.