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What is Drug of choice for the treatment of Taenia solium and Taenia saginata infestation is- and explain in detail?
Niclosamide is highly effective against Taenia solium & T.saginata. It acts by inhibiting oxidative phosphorylation in mitochondria & interfering with anaerobic generation of ATP by the tapeworm . Injured by niclosamide, the tapeworm are paly digested in the intestine. Reference: Harrison20th edition pg 1137