You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is All the following statements are true regarding beta-lactams except and explain in detail?
Among carbapenems, Imipenem should always be given with cilastatin to prevent renal failure and convulsions. No need to give mero and doripenem with cilastatin.Cross-resistance is not seen with aztreonam among beta-lactams.Methicillin is inactivated by gastric acid so administered parenterally.Ref: Katzung 3rd ed; pg 781