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What is Which of the following anticancer drug causes hemolytic uremic syndrome: and explain in detail?
Ref: KDT 6th ed. pg. 827* After 8-10 months of start of mitomycin-C treatment, the drug leads to endothelial damage* The Renal lesions seen are similar to those seen in idiopathic HUS and include arteriolar fibrin thrombi, expanded sub-endothelial zones in glomerular capillary walls.* HUS can be seen with: Mitomycin C, Gemcitabine