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What is About giant cell tumor, all are true except: and explain in detail?
Ans: C. Osteoclast giant cells constitute the proliferative component of the tumor(Ref: Robbins 9Ie p1204; Apley's 9Ie p202).In giant cell tumors, osteoclast giant cells are the malignant cells, which induce the proliferation of mononuclear macrophage lineage cells, hence the dividing cell population is the mononuclear cells which form the matrix.Osteoclast giant cells do not constitute the proliferative component of the tumor.