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What is A patient having prinzmetal angina is started with ISMN. Patient got symptomatic relief from angina. What is the MOA? and explain in detail?
ANS. A# Important points on nitrates1. All nitrates have high FPM metabolism except ISMN (Isosorbide mononitrate)2. Skin rashes are maximum with Pentaerythritol tetranitrate3. Nitrates used in acute attack: NTG and ISDN (Isosorbide dinitrite)