You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Antihypeensive used in angina pectoris is? and explain in detail?
The anti hypeensives used in angina pectoris is beta blockers . Beta-blockers These lower myocardial oxygen demand by reducing hea rate, BP and myocardial contractility, but they may provoke bronchospasm in patients with asthma. The propeies and side-effects of b-blockers are discussed on page 500. In theory, non-selective b-blockers may aggravate coronary vasospasm by blocking coronary aery b2-adrenoceptors, and so a once-daily cardioselective preparation such as slow-release metoprolol (50-200 mg daily) or bisoprolol (5-15 mg daily) is preferable. Beta-blockers should not be withdrawn abruptly, as rebound effects may precipitate dangerous arrhythmias, worsening angina or MI. This is known as the b-blocker withdrawal syndrome. Ref Harrison 20th edition pg 1567