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What is The following enzyme is required for the hexose monophosphate shunt pathway: and explain in detail?
Glucose-6-phosphate is oxidized by NADP+ dependent Glucose-6-phosphate dehydrogenase (GPD). 6-phospho glucono lactone is formed.
One molecule of NADPH is formed in the reaction. This is the rate-limiting step. Regulation is effected by this enzyme
 
Reference: Vasudevan 7th  ed, pg 130