You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Most common site for the initiation of otosclerosis: and explain in detail?
(c) Fissula ante-fenestrum(Ref. Cummings, 6th ed., 2212)Though otosclerosis ultimately results in the fixation of the footplate and margins of stapes which is lying over the oval window, it actually gets initiated most commonly in the immature cartilaginous area of the bony labyrinth which lies anterior to the fenestra of oval window and hence called fissula ante fenestrum.Fissula post-fenestrum area of the bony labyrinth is also cartilaginous but otosclerosis is uncommon here.