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What is A 20-year-old male came to the clinic with fatigue and weakness. Following findings were noted, what will be the likely diagnosis? and explain in detail?
Peripheral smear image shows blast with presence of rod-like cytoplasmic inclusion called as AUER ROD The other image shows Gum hyperophy, seen in some types of acute myeloid leukemia (AML). In AML with monocytic differentiation i.e. AML-M4 and AML-M5 (more commonly), infiltration of the skin (leukemia cutis) and the gingiva leading to gum hyperophy can be observed. In AML, there is an accumulation in the marrow of immature myeloid cells that lack the potential for fuher differentiation and maturation, which leads to suppression of normal hematopoiesis. The presence of myeloblasts in the peripheral blood is indicative of acute myeloid leukemia (AML).