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What is Feature(s) of Lipoid nephrosis is/are- and explain in detail?
Minimal Change Disease (Synonyms: MCD, Lipoid Nephrosis, Foot Process Disease, Nil Deposit Disease) In lipoid nephrosis the light microscopy shows no apparent abnormality, there will be a slight increase in the mesangial matrix at the most. Tubules show fine lipid vacuolation and hyaline droplets in cells of PCT, interstitium may be oedematous, no blood vessel changes. By electron microscopy, diffuse flattening of foot processes of the visceral epithelial cells(podocytes) hence also called foot processes disease or podocytopathy. By immunofluorescence microscopy- no deposits of compliments or immunoglobulins are recognized. From Textbook of pathology HARSH MOHAN 7th edition pg no:656