You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Digoxin toxicity is enhanced by all, except: and explain in detail?
Answer is D (Hepatic dysfunction) Digoxin toxicity is enhanced by renal failure as it is excreted through kidneys where as digitoxin toxicity is enhanced by liver failure because it is eliminated by hepatic metabolism. Hepatic dysfunction does not affect digoxin elemination. Reduced tolerance to digoxin may be seen in : Advanced age Q Acute myocardial infarction Q / ischaemia / hypoxemia Magnesium depletion Hypercalcemia Q Hypothyroidism e Renal insufficiency Q Electrical cardioversion. The administration of following drugs raises the serum concentration of digoxin : (by reducing both the renal and nonrenal elimination of digoxin and by reducing its volume of distribution) Quinidine Q Verapamil Amiodarone Propufenonedeg