You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A 41-year-old woman is known to have multiple endocrine neoplasia syndrome. She has multiple family members who have had adenoma tumors removed from the parathyroid, pancreas, and/or pituitary glands. She has severe diarrhea associated with low gastric acid secretion and a normal gastrin level. Which of the following serum assays would be best to evaluate the possible cause of the diarrhea? and explain in detail?
VIP producing tumors (VIPomas) are usually malignant, although benign tumors and hyperplasia may also occur. Increase of VIP results in the WDHA syndrome. Diarrhea is severe and results in fluid and electrolyte disturbances. Treatment is directed to removal of the pancreatic tumor. Gastrinoma is more common but is associated with increased gastrin level in the blood.