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What is All are true regarding G protein Except? and explain in detail?
G Protein have trimeric structure with alpha,beta and gamma subunits.But activated form has only GTP bound alpha subunit-GTP-alpha. The action is terminated when the GTPase activity of alpha subunit hydrolyses GTP to GDP.ADP ribosylation of alpha subunit leads to inhibition of GTPase activity. Ref:Murray R.K. (2011). Chapter 46. Intracellular Traffic & Soing of Proteins. In D.A. Bender, K.M. Botham, P.A. Weil, P.J. Kennelly, R.K. Murray, V.W. Rodwell (Eds), Harper's Illustrated Biochemistry, 29e.