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What is Drug of Choice for hypehyroidism in pregnancy: and explain in detail?
In a case of thyrotoxicosis during pregnancy, lodine-131 is contraindicated. Propylthiouracil is the drug of choice for thyrotoxicosis in pregnancy. It is highly protein bound and therefore less amount of drug is transferred across placenta and in milk. With carbimazole and methimazole there is risk of fetal hypothyroidism, aplasia cutis, and fetal agranulocytosis.