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What is The presence of the philadephia chromosome is associated with a worse prognosis in patients with which of the following diseases? and explain in detail?
The presence of the philadelphia chromosome a translocation from the long arm of chromosome 22 to chromosome 9 (t,9,22) is associated with a more ourable prognosis in patients with chronic myelogenous leukemia but is associated with an unourable outcome in Acute lymphoblastic leukemia. (ref Robbins 8th/603)