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What is Which of the following provides the best explanation for neostigmine being preferred over physostigmine for treating Myasthenia gravis and explain in detail?
Ref-KDT 6/e p103 Neostigmine is a quaternary ammonium derivative and is lipid insoluble. Its absorption from GIT penetration in the brain and cornea is much less than physostigmine . It produces additional action on NM receptor