You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Lymph node first involved in Ca breast is /are:
(A)Axillary
(B)Internal mammary
(C)Supraclavicular
(D)Contralateral axillary and explain in detail?
Lymphatic Spread in Carcinoma of Breast Occurs through:
• Subareolar Sappey's lymphatic plexus
• Cutaneous lymphatics
• Inflammatory lymphatics  Lymphatic drainage of the breast is predominantly through axillary (75%).
Posterior 1/3 rd of the breast are more likely to drain to the internal mammary nodes 1 ,
Involvement of supradaviular nodes & of any contralateral lymph nodes represents advanced disease