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What is Glycoprotein II b / III a receptor antagonists is and explain in detail?
(Abciximab) (573-KDT) (610-11-KDT 6th)Antiplatelet Drugs (Antithrombotic drugs)* Aspirin* Dipyridamole* Ticlopidine* Clopidogrel* * Glycoprotein lib /Ilia receptor antagonists - Abciximab, Eptifibatide and TirofibanAbciximab* Given along with aspirin + heparin during PTC A it has markedly reduced the incidence of restenosis, subsequent MI and death* Used in unstable angina and as adjuvant to coronary thrombolysis* Non antigenic, the main risk is haemorrhage. Thrombocytopenia is another complications.Antifibrinolvtics - EACA, Tranexaemic acid, Aprotinin