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What is Verapamil is contraindicated in all, except ? and explain in detail?
Ans. is 'b' i.e., Variant angina "All CCBs are effective in reducing frequency and severity of classical as well as variant angina". Due to these cardiodepressant effects, it is C/I in the following conditions. Sick sinus syndrome (causes cardiac arrest) A- V block (Accentuate conduction defects) Congestive hea failure Hypotensive states Ventricular tachycardias AF with accessory pathway or WPW syndrome. o Other conditions in which Verapamil is C/I. Digoxin toxicity ---> Increases plasma digoxin level by decreasing its excretion, toxicity can develop. Quinidine and disopyramide ---> Both these drugs have cardiac depressant action. Verapamil is not used with b blockers because their depressant effect on SA and AV node may add up. b