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What is Concentration of epinephrine used in neonatal resuscitation is and explain in detail?
Medications: indication, dosage and effects MedicationIndicationEffectsConcentration administeredDose of prepared solutionRouteEpinephrine (1:1000)HR <60 / min after 30 sec of effective PPV and chest compressions Inotropic; chronotropic; peripheral vasoconstrictor 1:100000.1-0.3 ml/kgIV; through umbilical vein (endotracheal route if no IV access) Normal salineRinger lactateAcute bleeding with hypovolemia Increased intravascular volume improves perfusion 10 ml/kgUmbilical vein Naloxone (0.4 mg/ml) Respiratory depression with maternal history of narcotic use within 4 hr of bihNarcotic antagonist 0.4 mg/ml 0.25 ml/kgIV preferred; delayed onset of action with intramuscular use; administer only after restoring ventilationSodium bicarbonate is administered only if prolonged asphyxia is associated with metabolic acidosis despite use of epinephrine and volume expanders.IV intravenous; PPV positive pressure ventilation Ref: Paediatrics; O.P. Ghai; 8th edition; Page no: 132