You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which of the following is true about the WHO analgesic ladder for chronic pain in adults? and explain in detail?
The 3 main principles: By the clock: Drugs should be given "around the clock" rather than "on demand". By the mouth: Oral route is preferred. By the ladder: Non-opioids - Mild opioids - Strong opioids. Non opioid analgesic are given for mild pain. Adjuvants can be used for mild, moderate and severe pain