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What is The drug preferred to stop the growth of prostate in a 70 year old male with Benign hyperplasia of prostate is and explain in detail?
Ref: Katzung 14th ed. pg. 1085* Most of the actions of testosterone are mediated by its conversion to DHT by 5-alpha reductase. Important amongst these are growth of prostate, male pattern baldness and hirsutism in females.* Finasteride and dutasteride are 5-alpha reductase inhibitors useful in the treatment of BPH, male pattern baldness and hirsutism by reducing the production of DHT.Note: Flutamide and Nilutamide act as antagonists of androgen receptors. These are useful for the treatment of prostatic carcinoma. Flutamide can cause gynaecomastia and reversible liver damage.