You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A 60-year-old male presents with hematuria, weight loss. Cystoscopy biopsy of the superficial lesion in bladder shows hyperchromatic nucleus, increased nuclear - cytoplasmic ratio, the lesion involves full thickness of epithelium but doesn't invade basement membrane. The diagnosis is: and explain in detail?
Ans. (c) Bladder Carcinoma in situRef: Bailey 26th Edition, Page 1333* Carcinoma in situ stands when the lesion does not invade basement membrane.