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What is Histological finding of solitary rectal ulcer syndrome is: and explain in detail?
Mucosal prolapse syndrome/ solitary rectal ulcer syndrome d/t chronic mechanical stimulation Recognized in prolapsing colostomies, inflammatory polyps, solitary ulcer or prolapsing hemorrhoid at the site of rectum - Microscopically, there is Intercryptal erosion, hyperplasia of crypts (some have peculiar diamond shape). Obliteration of lamina propria by fibroblasts, elastin & smooth muscle cells from muscularis mucosae Reduction in number of lymphocytes & plasma cells Thickening of the muscularis mucosa with splaying of its fibers.