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What is Which of the following statement is true about clomiphene citrate, EXCEPT: and explain in detail?
Although clomiphene is effective in inducing ovulation in perhaps 75% of women, successful pregnancy ensues in only 40-50% of those who ovulate. This has been attributed to clomiphene's inhibition of estrogen action on the endometrium, resulting in an environment that is not optimal for feilization and/or implantation. Ref: Schimmer B.P., Parker K.L. (2011). Chapter 66. Contraception and Pharmacotherapy of Obstetrical and Gynecological Disorders. In L.L. Brunton, B.A. Chabner, B.C. Knollmann (Eds), Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e.