You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which of the following is feature of arsenic toxicity? and explain in detail?
Ans. b (Non-cirrhotic portal fibrosis)> C. HCC. (Ref. Robbin's pathology, 7th ed., pg 907; Table 18-8)Hepatocellular damageExamplesAngiosarcomaVinyl chlorideNCPFArsenicMicrovesicular fatty changeTetracycline, salicylates yellow phosphorus, ethanolMacro vesicu lar fatty changeEthanol, methotrexate, amiodaroneCentrilobular necrosisBromobenzane, CCI4, acetaminophen, halothane, rifampinDiffuse or massive necrosisHalothane, isoniazid acetaminophen, methyldopa, trinitrotoluene,Amanita phylloides (mushroom) toxinHepatitis, acute and chronicMethyldopa, isoniazide, nitrofurantoin, phenytoin, oxyphenisatinFibrosis-cirrhosisEthanol, methotrexate, amiodarone, most drugs that cause chronic hepatitisGranuloma formationSulfonamides, methyldopa, quinidine, phenylbutazone, hydrala zine, allopurinolCholestasis (with or without hepato cellular injury) contraceptives, organic arsenicalsChlorpromazine, anabolic steroids, erythromycin estolate, oralContraceptives, organic arsenicals