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What is Coccidioides immitis is identified in tissues on the basis of which of the following and explain in detail?
Laboratory diagnosis of coccidioidomycosis: 1. Demonstration of spherules containing endospores in: (a) sputum or smears from the lesion stained by calcofluor white and (b) in biopsy material stained by hematoxylin and eosin, silver, or PerIodic acid-Schiff stains. H & E staining