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What is Cholelithiasis and choledocholithiasis is caused by? and explain in detail?
ANSWER: (A) ClofibrateREF: Robbin's 8th ed CH: 8Drugs causing cholelithiasis and choledocholithiasis:Clofibrates: Clofibrate, used to lower blood cholesterol, increases hepatic HMG-CoA reductase and decreases conversion of cholesterol to bile acids by reducing cholesterol 7-a-hydroxylase activity. The net result of these influences is excess biliary secretion of cholesterolEstrogen and OOP'SSomatostatin analogues appear to predispose to gallstones by decreasing gallbladder emptying.Ampicillin