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What is Homeobox gene is responsible for: and explain in detail?
Ans. A Segmental organization of embryo is craniocaudal directionRef: Netter's Atlas of Human Embryology, 2012 ed. pg. 10* Homeobox (HOX) gene is involved in segmental organization of embryo in cranio-caudal direction. The mutation in gene leads to formation of appendages in wrong locations.* Sonic hedge-hog gene is involved in patterning in A-P axis. The mutation in this gene leads to holoprosencephaly.