You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A lady has history of previous child birth with neural tube defect. What is the dose of folic acid to be given to prevent to neural tube defect in this child and explain in detail?
Dose of folic acid for primary prevention is 400 mcg / day
Dose of folic acid for secondary prevention (prevoius child affected with neural tube defect) is 4000 mcg / day started in periconception period = 1 month before to 3 months after conception.