You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A 40-year-old female presented to B/L parotid gland enlargement with complaints of dry eyes, dry mouth, chronic non-productive cough and shoness of breath. On examination, hepatosplenomegaly was noted. CT scan of chest Ceain tests were conducted. A biopsy from the affected salivary gland was also taken. Which of the following interleukins is involved in the pathogenesis of the above disease: - and explain in detail?
This is a case of Sjogren's syndrome. 1st image shows picture of ILD (honeycombing). 2nd image shows the Schirmer's test being conducted. 3rd image shows the lymphocytic infiltrate - suggestive of Sjogren syndrome. Presents with a triad of: - Dry eyes Dry mouth B/L parotid enlargement Also, there is Hepatosplenomegaly ILD Vasculitis Anemia of chronic disease Pathogenesis Presence of IL-18 positive macrophages Predominance of T-cells. Low levels of C4 complement.