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What is Antinuclear antibody specific for SLE is - and explain in detail?
Ans. is 'a' i.e., Anti ds DNA o Generic antinuclear antibody-Most sensitive for SLE.o Anti ds DNA & anti smith (Sm)-Most specific for SLE.o Anti histone-Drug induced lupus.o Anti-Ro & Anti-La-Neonatal lupus with congenital heart block and sjogren syndrome,o Anti DNA Topoisomerase (Anti Scl-70)-Diffuse systemic sclerosis (Diffuse scleroderma),o Anti - centromere-Localized systemic sclerosis (Localized scleroderma - CREST syndrome).o Anti Jo-1 (Histidyl-t-RNA synthase)-Inflammatory myopathies,o Anti U1 RNP-Mixed connective tissue disease.