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What is Digitalis has positive ionotropic effect by the viue of its effects on and explain in detail?
Effects of digitalis on cell biochemistry: sodium pumpinhibition. It is now generally agreed that Na+-K+ adenosine triphosphatase (ATPase), a transpo enzyme derived from the sarcolemmal sodium pump, is the primary site at which digitalis exes its effects on the myocardial cell. Refer kDT 6/e p497