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What is Type of nephropathy in DM- and explain in detail?
Nodular lesions of diabetic glomerulosclerosis are also called as Kimmelstiel-Wilson (KW) lesions or intercapillary glomerulosclerosis.These lesions are specific for type 1 diabetes (juvenile onset diabetes) or islet cell antibody-positive diabetes mellitus. The pathologic changes consist of one or more nodules in a few or many glomeruli. A nodule is an ovoid or spherical, laminated, hyaline, acellular mass located within a lobule of the glomerulus. The nodules are surrounded peripherally by glomerular capillary loopswhich may have normal or thickened GBM Ref: Harsh Mohan textbook of pathology page 678 6th edition