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What is DOC for acute attack of Hereditary angioneurotic edema? and explain in detail?
Ans. is 'b' i.e., Cl inhibitor concentrate o Hereditary angioedema (HAE) is a condition characterized by recurrent episodes of angioedema affecting the upper airway, bowel wall, or skin, which typically last two to four days.o The angioedema of HAE is mediated bv bradvkinin and does not respond to epinephrine, antihistamines. or glucocorticoids. Instead, first-line therapies for HAE act bv replacing the Cl inhibitor (ClINH)that is deficient pr dysfunctional in this disease or by inhibiting the production or function of bradykinin,o First-line therapies for HAE# Human plasma-derived C1 inhibitor concentrate (pdC1INH)# Recombinant human C1 inhibitor (rhC1INH)# Icatibant, a bradykinin B2-receptor antagonist# Ecallantide, a kallikrein inhibitor (available only in the United States)