You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is False regarding calcium homeostasis in pregnancy is? and explain in detail?
Ans. B. Serum ionized calcium levels fallTotal serum calcium levels, (which include both ionized and non-ionized calcium), decline during pregnancy, reduction follows lowered plasma albumin concentrations and, a consequent decrease in the amount of circulating protein- bound non ionized calcium. Serum ionized calcium levels remain unchanged. The fetal skeleton accretes approximately 30g of calcium by term, 80 percent of which is deposited during the third trimester. This demand is largely met by a doubling of maternal intestinal calcium absorption mediated, in part, by 1,25-dihydroxyvitamin D3 . Dietary intake of sufficient calcium is necessary to prevent excess depletion from the mother.