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What is In Gaucher's disease there is accumulation of ---inside the cells - and explain in detail?
Ans. is 'd' i.e., Cerebroside Lysosomal storage diseases o Lysosomes are key components of the intracellular digestive tract. o They contain a battery of hydrolytic enzymes. o These hydrolytic enzymes catalyze the breakdown of a variety of complex macromolecules. With an inherited deficiency of a functional lysosomal enzyme, catabolism of its substrate remains incomplete, leading to accumulation of the paially degraded insoluble metabolite within the lysosomes. Stuffed with incompletely digested macromolecules, these organelles become large and numerous enough to interfere with normal cell functions, giving rise to the lysosomal storage disorders.