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What is Drug used for smoking cessation and explain in detail?
Varenicline * Varenicline - paial agonist at alpha 3 beta 4, alpha 4 beta 2 & alpha 6 beta 2 subtypes of nAChRs and agonist at alpha 7 nicotinic Acetyl Choline Receptors. Block rewarding propeies of nicotine, alcohol and drugs of abuse. Ref:- Goodman & Gilman Pharmacological Basis of Therapeutics 13th Ed; Pg num:- 430