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What is EBV is associated with. and explain in detail?
Epstein-Barr Virus (EBV)is closely associated with nasopharyngeal cancer. EB virus has two impoant antigens:Viral capsid antigen(VCA) andEarly antigen(EA). IgA antibodies of EA are highly specific for nasopharyngeal cancer but have sensitivity of only 70-80% while IgA antibodies of VCA are more sensitive but less specific. IgA antibodies against both EA and VCA should be done for screening of patients for nasopharyngeal cancer.