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What is “Call-Exner bodies” are seen in and explain in detail?
GRANULOSA CELL TUMOR
■ It is a sex cord stromal tumor that occurs at any age but most common\y in postmenopausal woman (2/3rd).
■ It is a virilizing tumor, produces estrogen, causing precocious puberty in prepubertal girls and endometrial hyperplasia, cystic disease of breast and endometrial carcinoma.
■ These are potentially malignant tumors.
■ The tumor cells are arranged in sheets punctuated by small follicle like structures filled with an acidophilic material, known as Call-Exner bodies. Classification of Ovarian Tumors