You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Gold standard method of diagnosing celiac disease is: March 2012 and explain in detail?
Ans: A i.e. Small bowel biopsy Diagnosis of celiac disease Endoscopic small bowel biopsy is the gold standard for diagnosing celiac disease IgA anti-endomysial antibodies are detectable by immunofluorescence in most untreated cases. They are not quantitative, but are sensitivie (85-95%) and specific (approximately 99%) for the diagnosis, except in very young infants A full blood count in celiac disease may show microcytic or macrocytic anaemia from iron or folate deficiency and features of hyposplenism (target cells, spherocytes and Howell-Jolly bodies) Biochemical tests may reveal reduced concentrations of calcium, magnesium, total protein, albumin or vitamin D