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What is Most common vascular tumour in AIDS and explain in detail?
(Kaposi - sarcoma) (256 - R) (164- Basic pathology 8th)* Patients with AIDS have a high incidence of certain tumours especially Kaposi-sarcoma, non hodgkins B-cell lymphoma, cervical cancer in women and anal cancer in men* Kaposi - sarcoma is a vascular tumour that is otherwise rare in US is the most common neoplasm in patients with AIDS* The lesion of kaposi sarcoma are characterised by the proliferation of spindle cells that express markers of both endothelial (vascular or lymphatic) and smooth muscle lineages. There is also a profusion of slit -like vascular spaces, suggests that the lesions may arise from primitive mesenchymal precursors of vascular channels