You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Flutamide is used in CA - and explain in detail?
Ans. is 'b' i.e., Prostate Flutamideo It is a nonsteroidal drug.o Has antiandrogenic but no other hormonal activity-.o Its active metabolite 2-hydroxyflutamide competitively blocks androgen action on accessory sex organs as well as on pituitary - inceases LH secretion by blocking feed back inhibition - testosterone secretion increases which partially overcome the direct antiandrogenic action,o It is used in metastatic prostatic carcinoma.o It is better used in conduction with GnRH agonist to suppress LH and testosterone secretion,o Reports of liver damage have restricted its use,