You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Most common site of metastasis in choriocarcinoma and explain in detail?
(Lung) (233 - Shaw's 14th)CHORIOCARCINOMA - Malignant growths arising in the body of uterus* Most common, metastases are seen in the lungs (80%), brain and liver* Less common sites are GIT, kidney, spleen, genital tract and lymphnodes (10%)* "Cannon ball" metastasis in lung is typical of a malignant lesion* beta - hCG is very specific marker*** Purple haemorrhagic projections either into the lower third of the vagina or around the vaginal orifice is characteristic and pathognomic of chorio carcinoma* The development of chorio carcinoma following H. mole ranges between 2 - 10%* A post molar GTN may be benign or malignant. But a GTN after non-molar pregnancy is always a choriocarcinoma (201 - Dutta 6lh)