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What is Which of the following is the most abundant glycoprotein present in basement membrane? and explain in detail?
Laminin is a large extracellular glycoprotein found in basal membrane. It is the most abundant glycoprotein in basement membrane. It is typically cross shaped, formed by 3 disulphide bonded polypeptides. It binds to collagen (type IV), heparin sulphate and enactin. Ref: Robbins Pathologic Basis of Disease 6th Edition, Page 98, 100 ; Heparin and Heparan Sulfate Edited by Hari G. Gar, Page 700