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What is Treatment of choice for severe falciparum malaria is? and explain in detail?
Intravenous or intramuscular aesunate is the treatment of choice in severe malaria. Quinine can be used when aesunate is not available. Aemether by intramuscular route is acceptable as an alternative in the treatment of severe falciparum malaria during an epidemic. Ref: Harrison's Principles of Internal Medicine, 17th Edition, Pages 1288-9 ; Guidelines for The Treatment of Malaria By World Health Organization, 2nd Edition, Pages 17, 57 ; Essentials of Medical Pharmacology By KD Tripathi, 5th Edition, Pages 747-8