You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Not a predisposing factor for atherosclerotic plaque formation? and explain in detail?
B i.e. Alpha 2 - macroglobulinAtherosclerosis is a/w increased LDL (or oxidized LDL), Lp (a) & homocysteine and decreased or defective apo B-100 & EQ. Alpha-2 (a-2) macroglobulin, a large plasma glycoprotein (720 kDa) containing Zn (zinc) and a unique internal cyclic thiol ester bond (formed between cysteine & glutamine), is a panproteinase inhibitor (i.e. neutralize many proteases) and target ceain cytokines (like platelet-derived growth factor, transforming growth factor (3 etc) towards paicular tissues or cells. It is not a predisposing factor for atherosclerosisQ.