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What is The most common site of carcinoma esophagus is: and explain in detail?
The incidence of squamous cell esophageal cancer has decreased The rate of adenocarcinoma has risen dramatically. Adenocarcinomas arise in the distal esophagus in the presence of chronic gastric reflux and gastric metaplasia of the epithelium (Barrett's esophagus) They behave clinically like gastric adenocarcinoma and account for >70% of esophageal cancers. Distribution: About 10% of esophageal cancers - upper third of the esophagus (cervical esophagus) 35% in the middle third 55% in the lower third. Ref: Harrison,E-18,P-764.