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What is Function of Topoisomerases and explain in detail?
Classes of Proteins Involved in ReplicationProteinFunctionDNA polymerasesDeoxynucleotide polymerizationHelicasesATP -driven processive unwinding of DNATopoisomerasesRelieve torsional strain that results fromhelicase-induced unwindingDNA primaseInitiates synthesis of RNA primersSingle-strand bindingproteins (SSBs)Prevent premature reannealing of dsDNADNA ligaseSeals the single strand nick between thenascent chain and Okazaki fragments on the lagging strandRef: Harper&;s Biochemistry; 30th edition; Chapter 35; DNA Organization, Replication, & Repair