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What is All of the following statements are TRUE about second generation antihistaminic agents EXCEPT: and explain in detail?
1st generation 2nd generation Cross BBB, cause sedation Donot cross BBB, no sedation Ach blockade, anticholinergic side effect occur No Ach blockade Useful for - Motion sickness - Drug induced parkinsonism - Muscular dystonias - Allergy Useful only for allergy Promethazine, diphenhydramine, diphenhydrinate, phenramine, Terfenadine, fexofenadine, loratidine