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What is Most common cause of Vaccine failure is: and explain in detail?
- Primary vaccination failure: Failure to serologically respond to vaccine: Too young age where Maternal antibodies interfere (MC Cause) Vaccine production problems Cold chain failure Inappropriate administration technique Immunodeficiency Poor health - Secondary vaccination failure: 'Waning immunity' where there is loss of vaccine induced protection in an individual who had previously seroconveed to vaccination. Causes are not well understood.