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What is Exocytic release of ACH is blocked by ? and explain in detail?
Ans. is 'b' i.e., Botulinum ACETYLCHOLINE SYNTHESIS AND RELEASE Choline is actively taken up by the axonal membrane by Na+; choline cotranspoer. (Rate limiting step). This step is blocked by Hemicholinium. Choline is acetylated with the help of ATP and coenzyme 'A' by the enzyme choline acetyl transferase present in the axoplasm.