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What is All of the following are Vitamin-K deficiency features EXCEPT: and explain in detail?
Ans. (a) Associated thrombocytopenia with prolonged bleedingRef: Harrison 19th ed. / 96e-8* Vitamin-K is a fat soluble compound. It promotes blood clotting by increasing hepatic biosynthesis of prothrombin and other coagulation factors.* The best sources are green leafy vegetables, liver, cheese, butter and egg yolk. Deficiency, usually seen only in neonates, in disorders of absorption or during antibiotic therapy is characterized by hemorrhage.* Warfarin acts by inhibiting Vitamin K, and does not causes deficiency of the same.