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What is True statement about cyclooxygenase-2 is and explain in detail?
Ref-KDT 6/e p185 COX-1 is a house-keeping enzvme that is responsible for the generation of gastroprotective PGs. COX-2 is an inducible enzyme whose production is markedly increased at inflammatory sites. Indomethacin is a non-selective inhibitor of both isoforms of COX.