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What is Hypouricemia and explain in detail?
Hypouricemia or hypouricaemia is a level of uric acid in blood serum that is below normal.  In humans, the normal range of this blood component has a lower threshold set variously in the range of 2 mg/dL to 4 mg/dL, while the upper threshold is 530 μmol/L (6 mg/dL) for women and 619 μmol/L (7 mg/dL) for men.  Hypouricemia usually is benign and sometimes is a sign of a medical condition.

Presentation
Complications
Although normally benign, idiopathic renal hypouricemia may increase the risk of exercise-induced acute kidney failure. There is also evidence that hypouricemia can worsen conditions such as rheumatoid arthritis, especially when combined with low Vitamin C uptake, due to free radical damage.

Causes
Hypouricemia is not a medical condition itself (i.e., it is benign), but it is a useful medical sign.  Usually hypouricemia is due to drugs and toxic agents, sometimes it is due to diet or genetics, and rarely it is due to an underlying medical condition.  When one of these causal medical conditions is present, hypouricemia is a common sign.

Medication
The majority of drugs that contribute to hypouricemia are uricosurics (drugs that increase the excretion of uric acid from the blood into the urine)