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What is In cystic fibrosis mutation occurs at? and explain in detail?
Ans. (a) One gene(Ref: Robbins 9th/pg 466-470)Cystic Fibrosisis an Autosomal recessive disease, caused by mutation in Cystic Fibrosis Transmembrane conductance Regulator (CFTR) gene on chr7q31.2, which leads to abnormal function of ion transport channel.