You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Longest acting drug among the following drugs for over reactive bladder: and explain in detail?
Solefenacin is the longest acting drug from this group.
Gastro-intestinal tract

Anticholinergic drugs decrease the motility, tone and secretions in the gastrointestinal tract.

— Pirenzepine and telenzepine are selective M1 blockers useful in peptic ulcer disease.
— Hyoscine, dicyclomine, propantheline, oxyphenonium and clidinium are useful as anti-spasmodic agents for the treatment of intestinal colic.
— Darifenacin and solefenacin are selective M3 blockers useful for irritable bowel syndrome and overactive bladder.
Oxybutynin is shortest acting and solefenacin is longest acting drug from this group.
Mirabegron is a newer drug approved for overactive bladder. It acts by stimulating β3 receptors.