You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A variety of causative factors have been implicated in the development of Ca esophagus. Which of the following is NOT a predisposing factor for Ca esophagus? and explain in detail?
Etiologic Factors Believed to Be Associated with Esophageal Cancer: Excess alcohol consumption Cigarette smoking Other ingested carcinogens Nitrates (conveed to nitrites) Smoked opiates Fungal toxins in pickled vegetables Mucosal damage from physical agents Hot tea Lye ingestion Radiation-induced strictures Chronic achalasia Host susceptibility Human papillomavirus infection Esophageal web with glossitis and iron deficiency (i.e., Plummer-Vinson or Paterson-Kelly syndrome) Congenital hyperkeratosis and pitting of the palms and soles (i.e., tylosis palmaris et plantaris) Chronic gastric reflux (i.e., Barrett's esophagus) for adenocarcinoma Esophageal diveicula Ref: Phan A.T. (2011). Chapter 17. Gastric and Esophageal Cancer. In H.M. Kantarjian, R.A. Wolff, C.A. Koller (Eds), The MD Anderson Manual of Medical Oncology, 2e.