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What is Which of the following malformation in a newborn is specific for maternal insulin dependent diabetes mellitus ? and explain in detail?
The fetal malformations seen in Caudal regression syndrome are the most typical seen in cases of maternal diabetes'.- Early detection of caudal regression syndrome, D. Subtil et al.
Caudal regression :

Caudal regression syndrome (CRS) is a rare malfonnative syndrome seen mainly in cases of maternal diabetes with poor metabolic control.
This syndrome associates vertebral agenesis of variable level with genito-urinary and digestive malformations. These abnormalities are related to the impaired development of the mid-posterior axis mesoderm