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What is Drug of choice in methicillin-resistant Staphylococcus aureus - and explain in detail?
Methicillin resistance in S. aureus is determined by the mecA gene, which encodes for resistance to all b-lactam drugs. If CA-MRSA infection is suspected, either linezolid or vancomycin should be added to the initial empirical regimen. (Harrison's Principles of internal medicine, 20th edition)