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What is What is the cause of hypercoagulation in nephrotic syndrome: and explain in detail?
Thrombotic and thromboembolic complications are common in nephrotic syndrome due to loss of anticoagulant factor (e.g. antithrombin III, protein C and S) combined with increased platelet activation. Renal vein thrombosis is most often a consequence of this hypercoagulative state. There is also increased synthesis of fibrinogen in the liver.