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What is A female pt. present with a hard. mobile lump in her rt. breast. Which investigation would be most helpful in making the diagnosis - and explain in detail?
An open biopsy is the most definitive investigation.
CSDT writes -
"The most reliable diagnostic test for breast cancer is open excisional biopsy. When the sample is properly taken by the surgeon and examined by the pathologist, such a test should give no false-negative and no false-positive results."
" Large-needle (core needle biopsy) is an accepted diagnostic technique n which a core of tissue is removed with a large cutting needle. As in the case of any needle biopsy, the main problem is sampling error due to improper positioning of the needle, giving rise to a false negative test result."