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What is A 40 year male presented with massive splenomegaly. There was mild hepatic enlargement also. Peripheral blood film shows cells with hair like projections; which are positive for CD 25 and CD 103 and negative for CD 23. The likely diagnosis is a : and explain in detail?
Peripheral B - cell neoplasm Hairy cells on peripheral blood smear and CD 103 positivity are diagnostic of hairy cell leukemia which is a peripheral B cell neoplasm.