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What is The biochemical mechanism of action of digitalis is associated with: and explain in detail?
Digoxin is a cardiac glycoside. It directly inhibits Na-K ATPase and increases intracellular Na and decrease the extrusion of calcium. Thus increases intracellular Calcium. By increasing the calcium content and sodium content, force of contraction increases. (Ref-Essential of medical pharmacology K D TRIPATHI 6 Edition)