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What is true about TRIAD congenital rubella syndrome and explain in detail?
Answer: A. PDA, cataract and deafness is seenCongenital rubella syndrome (CRS) can occur in a developing fetus of a pregnant woman who has contracted rubella, usually in the first trimester. If infection occurs 0-28 days before conception, the infant has a 43% risk of being affected.Infection in 2nd trimester - may be deafness only.>6 wks - no major abnormalitiesDiagnosis: Isolation of virus in cell cultures of throat samples, urine or other secretions.Detection of IgM in single serum sample sholy after bih.Persistance of Rubella IgG antibodies serum beyond 1 year or rising antibody titer anytime during infancy in an unvaccinated child