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What is G6PD is enzyme of: and explain in detail?
Ans. (b) Cell membraneRef: Lippincotts Biochemistry 6th ed. P 151-152* G6PD enzyme is located at the cell membrane. RBC membrane is one such example, and is associated with severe pathology* Location: X chromosome at q28 locus. (G6PD enzyme is X-linked gene)* It protects the RBC from the deleterious effects of oxidizing agents by reducing themselves to NADPH.* In deficiency of G6PD enzyme - impaired ability of RBC to form NADPH - Hemolysis