You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which one of the following makes epiphyseal cailage matrix fail to calcify? and explain in detail?
In the absence of vitamin D, epiphyseal chondrocytes continue to proliferate, but their matrix does not calcify, which leads to rickets.