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What is In Alibe bazin syndrome, origin of lymphoma is from: and explain in detail?
Albe Bazin Syndrome (Mycosis Fungoides):- Neoplastic Proliferation of mature CD4 T cell Infiltrates the skin producing localized skin rash, plaque, and nodule. Aggregates of neoplastic cells in epidemic are called Pautrier's micro-abscesses (Epidermatropism) Cell can spread in blood producing Sezary syndrome:- Characteristic lymphocyte with cerebriform nuclei( Sezary cells) Also k/a Cutaneous T cell lymphoma Rx- Topical steroid and exposure to UV rays Vorinostat (Histone deacetylase inhibitor)