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What is True about barbiturates ? and explain in detail?
Ans. is ,a, i.e., Have steep dose response curve(Ref: Goodmen & Gillmen |2',h/e p. 471)Barbiturates depress all areas of CNS, but the reticular activating system is most sensitive.Barbiturates have steep dose response curve.Except For phenobarbitone in epiteliu andthiopentonein anaesthesia,barbituratesare used now'The enzwe inducing propey- of jhnobarbitine can be utiliad to hasten clearance of congenital nonhemolytic jaundiceand kernicterus,There is no specific antidote for their pokoning