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What is Leukocyte common antigen is: and explain in detail?
Ans. (a) CD 45(Ref: Robbins 9th/pg 590; 8th/pg 600; Wintrobe's 12th/pg 2522)CD 45Found in all hematopoietic cells except erythrocytes.CD45 plays an essential role in lymphocyte activation.Peripheral blood naive T cells are CD45RA, whereas memory (activated) T cells are CD45RO+