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What is A15 year old boy presented with pancarditis, on myocardial biopsy, following finding was seen. Diagnosis? and explain in detail?
Ans. (a) Aschoff noduleHere one can see collection of foci of swollen eosinophilic collagen surrounded by: Lymphocytes (primary T cells), Occasional plasma cells, Aschoff giant cells Q (macrophages of rheumatic fever) Q and Antischkow cells (cells with caterpillar like chromatin marked with an arrow)