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What is Darling disease is caused by - and explain in detail?
Histoplasmosis or Darling's disease is caused by dimorphic fungus - Histoplasma capsulatum. It is called Darling's disease because it was found by Samuel Darling in histopathologic specimens about a century ago. Reservoir: Humid and acidic soil containing bird or bat droppings. Clinical Manifestations: Pulmonary histoplasmosis: It is the most common form. Acute form stas as mild flu like illness Chronic form - Cavitary histoplasmosis Disseminated histoplasmosis develops if CMI is very low (as in HIV).