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What is Alpha-fetoprotein is a tumor marker for and explain in detail?
Answer- A. Hepato cellular carcinomaAlpha-feto protein (AFP)AFP is a well estabilished tumor markerIt is a glycoprofein synthesized normaily early in fetal life by the yolk sac, fetal liver and fetal GIT.AFP is raised in -Carcinomas > Liver Ca, Lung Ca, Colon Ca, Pancreatic Ca, Non-seminoma germ cell tumor of testis.Non-neoplastic conditions > Cirrhosis, Hepatitis, Pregnancy