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What is A 50 year old male is taking medication for tuberculosis since the last 2 months comes to the OPD with a complaint of hearing problems. The drug with which of the following mechanisms of action is most likely causing these symptoms? and explain in detail?
Streptomycin used in Tuberculosis produce ototoxicity. Aminoglycosides act by inhibiting protein synthesis after binding to the 30s ribosome and inhibiting 1st step - initiation complex formation.Ref: Katzung 13th ed Pg 799