You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which among the following is NOT a coenzyme of pyruvate dehydrogenase during the decarboxylation of pyruvate? and explain in detail?
Pyruvate is oxidatively decarboxylated by pyruvate dehydrogenase (PDH) complex, producing acetyl CoA, which is the major fuel for the tricarboxylic acid cycle. This multienzyme complex requires five coenzymes: Thiamine pyrophosphate Lipoic acid FAD NAD+ Coenzyme A Pyruvate dehydrogenase is inhibited by its products, acetyl-CoA, and NADH Ref: Biochemistry By Richard A. Harvey (Ph. D.), Richard A. Harvey, Denise R. Ferrier, 2011, Page 114.