You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is In a survey, many children are examined and were found to have urogenital abnormalities. Which congenital anomaly is associated with increased risk of bladder carcinoma? and explain in detail?
Ectopia vesicae(extrophy of the bladder)is incomplete development of the infraunbilical pa of the anterior abdominal wall and anterior bladder wall.Umbilicus is absent & there is separation of pubic bones.In males,epispadias is commonly present with rudimentary prostate & seminal vesicle In females,defective external genitalia is common.Problems associated with bladder extrophy are repeated soakage,ulceration,pain,recurrent pyelonephritis,renal failure,Metaplastic changes in mucosa can lead into adenocarcinoma of bladder. Reference:SRB's manual of surgery,5th edition,page no:1029