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What is Which of the following hormonal concentration decreases with age? and explain in detail?
Secretion of growth hormone (GH) and IGF-1 levels decline during advancing years-of-life. These changes (somatopause) are associated with loss of vitality, muscle mass, physical function, together with the occurrence of frailty, central adiposity, cardiovascular complications, and deterioration of mental function.Ref: Ganong&;s review of medical physiology; 24th edition; page no: 327