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What is Inherited coagulation disorders are and explain in detail?
Ref Harrison 16/e p685 Primary (Genetic) Common (>1% of the Population) Factor V mutation (G1691A mutation; factor V Leiden) Prothrombin mutation (G20210A variant) 5,10-Methylene tetrahydrofolate reductase (homozygous C677T mutation) Increased levels of factor VIII, IX, or XI or fibrinogen Rare Antithrombin III deficiency Protein C deficiency Protein S deficiency Very Rare Fibrinolysis defects Homozygous homocystinuria (deficiency of cystathione b-synthetase)