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What is Which of the following drugs, is used for Smoking Cessation? and explain in detail?
Answer is B (Bupropion): Bupropion (along with Varenicline and Nicotine replacement therapy) is a USFDA approved first line agent for pharmacotherapy in Smoking Cessation. USFDA Approved Agents for Smoking Cessation Nicotine Replacement Therapy (Transdermal Patch, gum, lozenges, oral inhaler, nasal spray) Bupropion (Atypical Antidepressant with dopaminergic and noradrenergic activity) Varenicline (Selective paial agonist at the Alpha4-Beta2 Nicotinic A-Choline receptor that is believed to mediate nicotine dependence) Clonidine and Noriptyline are two other medications that have efficacy but are NOT USFDA approved for this indication. These are classified as second line agents.