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What is Drug induced poal hypeension is seen with and explain in detail?
Vitamin A induced Hepatotoxicity Normal dose of vitamin A are not associated with liver injury or liver test abnormalities, but higher doses can be toxic Mechanism of injury : Excess Vitamin A is stored in stellate cells in the liver and accumulation can lead to their activation and hyperophy, excess collagen production, fibrosis and liver injury Serum bilirubin is typically only mildly elevated Liver biopsy is diagnostic Ref: Internet sources