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What is Regarding dihydroaemisinin pharmacokinetics, all are true except:- and explain in detail?
Dihydroaemisinin * It has potent schizontocidal action.* These drugs are lethal to early malarial gametes but not mature ones.* They do not kill vivax hypnozoites* The duration of action is sho and recrudescence rate is high.* Dose adjustment is not required in hepatic or renal failure.* Oral bioavailability is around 30%* Auto induction of metabolism.