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What is Involvement of sweat gland, dermal appendages, and hair follicles with epitheloid granuloma are typical features of which of the following? and explain in detail?
A i.e. Lichen scrofulosorum Tuberculids is hypersensitivity reaction to mycobacterium tuberculosis, where the evidence of etiology is not definite but show tubercular granuloma on histology & a positive response to antitubercular treatment. - Lichen scrofulosorum & papulonecrotic tuberculide are two definite (true) tuberculidesQ. Papulonecrotic variety is most common and clinically present with chronic, recurrent, symmetrical, necrotizing eruption of papules arising in crops and primarily involving arms & legs. A hallmark is that lesion heals with varioliform scarring. Lichen scrofulosorum is an uncommon asymptomatic lichenoid eruption of minute (0.5-3mm) papules occurring in children and adolescents with strongly positive tuberculin reaction. It mainly involves perifolicular distribution on abdomen, chest, back & proximal limbsQ. A hallmark is that superficial epitheloid dermal granulomas surround hair follicles and sweat ducts and may occupy several dermal papillaeQ.