You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Cryptococcus rarely cause infection of and explain in detail?
Cryptococcus neoformans, a capsulated yeast is the causative agent, it is the only deep mycoses present in India .
It has a spherical budding cell with a prominent polysaccharide capsule.
It is a true yeast and gram positive the capsule can be demonstrated using india ink or nigrosin staining 
Disease is usually asymptomatic and seen in immunocomprmised individuals, pulmonary cryptococcosis may lead to mild pneumonitis, cryptococcal meningitis occurs by haematogenous spread, skin, bone and lymph nodes are most commonly affected.

Ref : Textbook of Microbiology, C P Baveja 5th Edition pg no:556