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What is A 40-year male patient who is a known smoker presents with fever, fatigue and complete aversion to cigarette smoking. On examination he has icterus with an enlarged tender liver. LFT shows Total bilirubin 17.5 mg% Direct bilirubin 5.5 mg% SGOT 700 IU SGPT 900 IU What investigations will you do for ruling out acute viral hepatitis? and explain in detail?
LFT repo shows elevated bilirubin with conjugated bilirubin >15% of total serum bilirubin. SGOT and SGPT elevation indicates cytopathic effect of probably a virus. For diagnosis of acute viral hepatitis four serological tests should be performed. These are: 1. HbsAg 2. IgM Anti- HBc 3. IgM Anti- HAV 4. Anti- HCV Absence of all of these serological markers is consistent with diagnosis of non-A, non-B and non-C hepatitis. Presence of positive test for only Anti- HCV confirms the diagnosis of acute hepatitis C.