You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is The Lab investigation of a patient shows |T4, & |TSH Which of the following is the most likely diagnosis: and explain in detail?
|T4, & |TSH - suggests primary hypothyroidism Chronic thyroiditis or Hashimoto's disease is a common thyroid gland disorder. It can occur at any age, but is most often seen in middle-aged women. It is caused by a reaction of the immune system against the thyroid gland. The disease begins slowly. It may take months or even years for the condition to be detected. Chronic thyroiditis is most common in women and people with a family history of thyroid disease. Laboratory tests to determine thyroid function include: 1. Free T4 test (low) 2. Serum TSH (high) 3. T3 (low or normal) Thyroid autoantibodies: Antithyroid peroxidase pothalamic failure are causes of secondary hypothyroidism with low TSH and T4 Ref: Harrison's 16th Edition, Page 2109 (table)