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What is Methotrexate toxicity is prevented by giving? and explain in detail?
Ans. is 'b' i.e., Folinic acid * Folinic acidFor preventing methotrexate toxicity* AllopurinolTo prevent hyperuricemia caused by rapid destruction of cells during cancer chemotherapy.* Lithium carbonateIt has stimulant effect on bone marrow, so used during myelosuppresive drug therapy.* OndensetronFor controlling cytotoxic drug induced vomiting.* MesnaFor prevention of cyclophosphamide/ formamide indused hemorrhagic cystitis