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What is Cullen's sign is seen in: March 2013 and explain in detail?
Ans. C i.e. Acute hemorrhagic pancreatitis Cullen's sign It is superficial edema and bruising in the subcutaneous fatty tissue around theumbilicus. It is named for Thomas S. Cullen (1869-1953), an obstetrician who first described the sign in ruptured ectopic pregnancy in 1916. This sign takes 24-48 hours to appear and can predict acute pancreatitis, with moality rising from 8-10% to 40%. It may be accompanied by Grey Turner's sign (bruising of the flank), which may then be indicative of pancreatic necrosis with retroperitoneal or intraabdominal bleeding.