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What is Anti-coagulant of choice for heparin induced thrombo.. Cytopenia is? and explain in detail?
Lepirudin is a parenterally acting direct thrombin inhibitor. They inactivate fibrin bound thrombin in their clots since their activity is independent of antithrombin III. It&;s use has been approved in HIT. From medical pharmacology padmaja 4th edition Page no 338