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What is Greater risk of transformation into carcinoma is seen in: March 2009 and explain in detail?
Ans. C: Intestinal metaplasia Intestinal metaplasia is the transformation (metaplasia) of epithelium, usually of the stomach, to a type that bears some resemblance to the intestine. Initially, the transformed epithelium bears resemblance to the small intestine; in the later stages, the epithelium resembles the colon. It is characterized by the appearance of goblet cells It is considered to be a risk factor for the development of adenocarcinoma