You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is A newborn infant becomes markedly jaundiced on the second day of life, and a faint petechial eruption, first noted at birth, is now a generalized purpuric rash. Hematologic studies for hemolytic diseases are negative. Acute management should include which of the following? and explain in detail?
Although hypothyroid neonates may develop hyperbilirubinemia, the patient described most likely has a congenital or acquired infection requiring immediate diagnosis and, if possible, treatment. Among the important causes of neonatal sepsis are prenatal infections, including congenital syphilis, toxoplasmosis, cytomegalovirus infection, and rubella. Useful diagnostic studies, in addition to cultures for bacteria, include specific serologic tests for pathogens, viral cultures, lumbar puncture, and x-rays of the chest and long bones. Longitudinal striations in the metaphysis are characteristic of congenital rubella, whereas osteochondritis or periostitis usually indicates congenital syphilis. Congenital syphilis, cytomegalovirus, and rubella can be highly contagious. Urine can contain rubella virus for more than 6 months and is, therefore, a special hazard to nonimmune pregnant women.