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What is True regarding Oncogenes are all except ? and explain in detail?
Protooncogenes o These are physiological regulator of cell proliferation ando They act under proper physiological stimuli.o Without physiological stimuli they will be silent and there will be no replication.Oncogenes When, due to any cause (mutation or overexpression), protooncogenes become autonomous, i.e. they promote cell growth without any physiological stimulus.So, oncogenes is derived from protoncogens.o Infact oncogene and protooncogene is the same, in normal cell it acts as protooncogen while in cancer cell it acts as oncogene.Oncoproteins o Oncogenes encode proteins called Oncoproteins which resemble the normal products of protoncogenes with the exception that ?(a) Oncoproteins are devoid of impoant regulatory elements.(b) Their production in the transformed cells does not depend on growth factors or other external signals.Proto-oncogenes (Normal genes required for cell proliferation and differentiation) Oncogenes (Genes promoting autonomous cell growth in cancer cells) Oncoproteins (Proteins lacking regulatory control and responsible for promoting cell growth)