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What is The Karyotype of a complete mole is: and explain in detail?
Complete moles have a normal karyotype of 46XX in 90% of the cases, usually resulting from an empty ovum feilized by a single sperm with subsequent reduplication of its haploid set of chromosomes. In approximately 5%, the complete mole has a 46XY karyotype, which occurs when two sperms (one carrying an X chromosome and the other carrying a Y chromosome) feilize an empty ovum. The Karyotype of a incomplete or paial mole is 69 XYY or 69 XXY. Ref: Gynecological Cancer Management: Identification, Diagnosis and Treatment edited by Daniel Clarke-Pearson, John Soper, 2011, Chapter 14 ; Text Book of Obstetrics by D.C.Dutta, 6th edition, Page 194, Page 200.