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What is Brown tumor is seen in and explain in detail?
Primary hyperparathyroidism is a disease characterized by excessive secretion of parathormone which results in increased osteoclastic activity therby causing bone loss . The bone loss predisoses to microfractures and secondary hemorrhages that elicit an influx of macrophages and an ingrowth of reparative fibrous tissue, creating a mass of reactive tissue known as brown tumor . Ref: Robbins and cotrans 9e Pg 1102