You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is An i.v. bolus dose of thiopentone leads to loss of consciousness within 10-15 sec. The patient regains consciousness in just a few minutes. This is because it is: and explain in detail?
(Ref: KDT 6/e p374) Thiopentone and other highly lipid soluble agent first reach the highly perfused organs like brain. therefore, onset of action of these agents is very quick. However, action also terminates quickly because of redistribution to less well perfused tissues like fat and muscle.