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What is Which is true about type II hypersensitivity reaction? and explain in detail?
Type II or Cytotoxic Hypersensitivity depends on the abnormal production of IgG or IgM directed against tissue antigens or a normal reaction to foreign antigens expressed on host cells. There are three main mechanisms of injury in Type II reactions:* Activation of complement followed by complement mediated lysis or phagocytosis and removal by leukocytes* Antibody dependent cellular cytotoxicity* Inactivation of a biologically active molecule