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What is Drug of choice for maternal toxoplasmosis and explain in detail?
Ref: Text book of Obstetrics by D.C.Dutta. 7th ed. Pg. 297.Explanation:Treatment of choice for toxoplasmosis during pregnancy:Spiramycin 3 g/dayPyrimethamine 25mg + sulphadiazine 1 gQlD for 4-6 weeksPyrimethamine is not given in 1' trimesterMode of infection : Eating raw, Uncooked meat/ through cat feces/ Through placentaEffects on baby:HydrocephalusChorioretinitisCerebral calcificationsMicrocephalyMental retardation