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What is A 40yr old male presenting with URTI, hemoptysis and has elevated cANCA value is most likely having and explain in detail?
Ans: b) Wegner's granulomatosis Wegner's granulomatosis is a necrotizing vasculitis characterized by:i) Acute necrotizing granuloma of URT/LRTii) Necrotizing vasculitis involving small to medium vesselsiii) Renal disease - focal necrotizing crescentic glomerulitiscANCA is positive in 95% of all patients with acute generalized disease. Arise in titre suggest relapse.cANCA typically found in Wegner's granulomatosispANCAMicroscopic polyangitisChurg strauss syndromeGood pasteur's syndromeIdiopathic crescentic glomerulonephritis