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What is 25-year-old woman is being treated for a laceration to the forearm. Local anesthesia is used prior to suturing. An allergic reaction is most likely to occur with wof local anesthetics and explain in detail?
The clinically useful LAs are weak bases with amphiphilic propey. A hydrophilic secondaryor teiary amine on one side and a lipophilic aromatic residue on the other are joined by an alkyl chain through an ester or amide linkage. Ref :- kd tripathi; pg num:-360,361