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What is Branching enzyme is found in and explain in detail?
Glycogen synthesis:- i. The glycogen synthase can add glucose units only in the alpha-1,4 linkage. A branching enzyme is needed to create the alpha-1,6 linkages. ii. When the chain is lengthened to 11 - 12 glucose residues, the branching enzyme will transfer a block of 6 to 8 glucose residues from this chain to another site on the growing molecule. The enzyme amylo--transglucosidase (branching enzyme) forms this alpha-1,6 linkage (Fig. 9.37). iii. To this newly created branch, fuher glucose units can be added in alpha-1,4 linkage by glycogen synthase.Ref: DM Vasudevan, 7th edition, page no: 125