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What is Paradoxical response of GH release to TRH is seen in: and explain in detail?
Answer is B (Acromegaly): In patients with Acromegaly TRH can cause a paradoxical increase in GH secretion which is not observed in normal individuals. 'About 60% of patients with GH secreting tumors (Acromegaly) may exhibit paradoxical GH response to TRH administration'- Harrison 16th/2090