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What is Rubeosis iridis and explain in detail?
Rubeosis iridis is a medical condition of the iris of the eye in which new abnormal blood vessels (formed by neovascularization) are found on the surface of the iris.

Causes
This condition is often associated with diabetes in advanced proliferative diabetic retinopathy. Other conditions causing rubeosis iridis include central retinal vein occlusion, ocular ischemic syndrome, and chronic retinal detachment.

Pathophysiology
It is usually associated with disease processes in the retina, which involve the retina becoming starved of oxygen (ischaemic).   The ischemic retina releases a variety of factors, the most important of which is vascular endothelial growth factor (VEGF).  These factors stimulate the formation of new blood vessels (angiogenesis).  These new vessels do not have the same characteristics as the blood vessels originally formed in the eye