You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Poor prognostic indicator in ALL- and explain in detail?
Poor prognostic factors in ALL Age less than two years, largely because of the strong association of infantile ALL with translocation involving MLL gene. Presentation in adolescence oor adulthood Peripheral blood blast count greater than 100000 which probably denotes a high tumour burden. Reference : Robbins and Cotran Pathologic basis of disease.South Asia Edition volume 1.page no. 592