You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is The transmission of HIV-1 transplacentally is ? and explain in detail?
Ans. is 'c' i.e., 30-40%. Perinatal transmission of HIV: Veical transmission to the neonates is about 14-25%. Transmission of HIV 2 is less frequent (1-4%) than for HIV 1 (15-40%). Transplacental transmission occurs: 20% before 36 weeks, over 80% of transmissions occur around the time of labor and delivery. Veical transmission is more in cases with preterm bih and with prolonged membrane rupture. Risks of veical transmission is directly related to maternal viral load (measured by HIV RNA) and inversely to maternal immune status (CD4+ count). Maternal anti-retroviral therapy reduces the risk of veical transmission by 70% Breastfeeding doubles the risk of MTCT transmission (14% to 28%).