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What is All of the following statements about immunosuppressants are true EXCEPT : and explain in detail?
Mycophenolate mofetil acts by blocking IMP dehydrogenase.
Cyclosporine and tacrolimus are calcineurin inhibitors that act by decreasing the transcription of IL-2 gene. Cyclo­sporine is commonly used to prevent rejection in transplant recipients.
Sirolimus acts by inhibiting mTOR (a tyrosine kinase) that is the target of IL-2.