You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is The following antiasthma drug is not a bronchodilator and explain in detail?
Bronchodilators :- a) b2 Sympathomimetics: Salbutamol, Terbutaline, Bambuterol, Salmeterol, Formoterol, Ephedrine. B) Methylxanthines: Theophylline (anhydrous), Aminophylline, Choline theophyllinate, Hydroxyethyl theophylline, Theophylline ethanolate of piperazine, Doxophylline. C) Anticholinergics: Ipratropium bromide, Tiotropium bromide. Sodium cromoglycate:- mech of action :- It inhibits degranulation of mast cells by trigger stimuli(MAST CELL STABILISER). Bronchospasm induced by allergens,irritants,coldair and exercise may be attenuated. It is also not a bronchodilator and does not antagonize constrictor action of histamine, ACh, LTs, etc. Therefore, it is ineffective if given during an asthmatic attack. Pharmacokinetics:- Sod. cromoglycate is not absorbed orally. It is administered as an aerosol through metered dose inhaler it is rapidly excreted unchanged in urine and bile. uses:- 1. Bronchial asthma: Sod. cromoglycate is a long-term prophylactic in mild-to-moderate asthma. Decrease in the frequency and severity of attacks is more likely in extrinsic (atopic) and exercise-induced asthma, especially in younger patients. 2. Allergic rhinitis 3. Allergic conjunctivitis Ref:- kd tripathi; pg num:- 222,229