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What is A patient with Miller Dieker syndrome on neuroimaging showed a smooth coex with no involutions. This condition of the brain where the convolutions are absent is called? and explain in detail?
Smooth cerebral coex with no convolutions is called Lissencephaly. It may be associated with microcephaly, developmental delay, seizure, optic nerve hypoplasia and microphthalmia. Holoprosencephaly means a single sphered brain. Rachischisis is congenital fissure of veebral column. Ref: Oxford Handbook of Clinical Specialities, Edition 8, Page - 139