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What is Which of the following antineoplastic drug causes pulmonary toxicity? and explain in detail?
Bleomycin causes pulmonary toxicity in the form of pneumonitis, dry cough, rales and later pulmonary fibrosis. These complications occur when total dose of 200 units is exceeded.5-Fluorouracil causes myelosuppression, stomatitis and diarrhoea.Cisplatin is nephrotoxic and ototoxic. Ototoxicity affects 4000 to 8000 Hz which may be permanent.Vincristine is neurotoxic and causes sensory or motor peripheral neuropathy.