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What is A patient of thrombosis of veins has been receiving coumarin therapy for three years. Recently she developed bleeding tendency. How will you reverse the effect of coumarin therapy? and explain in detail?
Ans. (B) Vit. K injection(Ref: KDT 8/e p661,662)Vitamin K is used to reverse bleeding tendency (raised INR) in warfarin overdose whereas fresh frozen plasma is treatment of choice for bleeding due to warfarin.