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What is Nelson syndrome is seen following and explain in detail?
Nelson's syndrome also referred to as post adrenalectomy syndrome occurs following bilateral adrenalectomy in patients with pituitary dependant Cushing's syndrome. The common symptoms include: hyper-pigmentation of the skin, visual disturbances, headaches, abnormal high levels of beta-MSH and ACTH, abnormal enlargements of the pituitary gland(invasive pituitary macroadenoma), interruption of menstrual cycles in women.Reference : page 776 Davidson's principles and practice of Medicine 22nd edition