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What is The tumor marker for Endodermal sinus tumor is and explain in detail?
Endodermal sinus Tumors often have eosinophilic hyaline globules in which a1-antitrypsin and alpha fetoprotein (AFP) can be demonstrated by immunohistochemical techniques. As mentioned later, AFP can also be detected in the serum .Serum AFP is a very good tumor marker in patients with germ cell tumors composed of or containing endodermal sinus (yolk sac) tumor, irrespective of their location. ref : Robbins Basic Pathology, 9E,page-661