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What is Neurotensinoma causes- and explain in detail?
Answer is option 4 Neurotensinomas Vinik A. Publication Details Neurotensin (NT) is a 13 amino acid polypeptide first extracted from bovine brain by Carraway and Leeman(1). It subsequently was isolated from the human GI tract and found to have the same amino acid sequence(2). Neurotensin has a number of interesting pharmacologic effects that include hypotension, tachycardia, and cyanosis (3)(4) and stimulation of secretion from the small intestine (5). It also has been repoed to inhibit the interdigestive myoelectric complex and stimulate insulin release(6). NT also increases venous vascular permeability, raises blood glucose, (7)(8)(9)and lowers blood pressure(1)(4). Ref: Neurotensin is a 13 amino acid peptide produced by the N cells of the ileal mucosa. It stimulates intestinal secretion and motility, and inhibits gastric secretion.