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What is True about Wilson's disease and explain in detail?
Wilson disease is an inborn error of metabolism due to toxic accumulation of copper in the liver, brain, cornea and other tissues.
Serum ceruloplasmin is decreased(<20 mg/dl) and the 24-hour urinary copper excretion is more than 100 micrograms/day.
Hepatic copper values usually above 250 micrograms /gram of dry weight of liver.