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What is Not seen in Korsakoff's syndrome and explain in detail?
As Korsakoff's psychosis often follows Wernicke's encephalopathy; these are together referred to as Wernicke-Korsakoff syndrome. Clinically, Korsakoff's psychosis presents as an organic amnestic syndrome, characterised by gross memory disturbances, with confabulation. Insight is often impaired. The neuropathological lesion isusually wide-spread, but the most consistent changes are seen in bilateral dorsomedial nuclei of thalamus and mammillary bodies. The changes are also seen in periventricular and periaqueductal grey matter, cerebellum and pas of the brainstem. The underlying cause is believed to be usually severe untreated thiamine deficiency secondary to chronic alcohol use. Ref: A Sho Textbook of Psychiatry, Niraj Ahuja, 7th Edition, pg. no.38