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What is In juvenile myoclonic epilepsy (JME), which is the most common presentation? and explain in detail?
Juvenile myoclonic epilepsy (JANZ syndrome) - Polygenetic inheritance, Strong family history - Onset: 10 -19 yrs. - Myoclonic Jerk (early morning) and prominent in morning after awakening. Consciousness is preserved unless severe - EEG: 4-6 Hz Polyspike pattern seen. - May develop GTCS in future and in 30% will also develop absence seizure in future Rx - Valproate (lifelong)