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What is A 16-year-old boy is admitted with fever, icterus, conjunctival suffusion and hematuria for 15 days. Which serological test should be done for diagnosis? and explain in detail?
Microscopic agglutination test is used for diagnosis of Leptospirosis. History of fever with liver(icterus) and kidney(hematuria) involvement should arouse suspicion for leptospirosis (Weil&;s disease). Serotype-specific tests: Microscopic agglutination test Macroscopic agglutination test WIDAL test is used to screen for typhoid fever Weil Felix reaction is used to diagnose rickettsial fevers Paul Bunnell test is the investigation of choice for infectious mononucleosis. Reference: Ananthanarayan and Paniker&;s Textbook of Microbiology Tenth edition