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What is All of the following nondepolarising neuromuscular blocker causes histamine release except- and explain in detail?
All benzylisoquinoline nondepolarising neuromuscular blocker causes histamine release. Aminosteroid group does not release histamine. NDNB divided in three group according to duration of action - Long- acting, intermediate - acting and sho- acting. Aminosteroid Long acting Pancuronium pipecuronium Benzylisoquinoline D-tubocurane, Doxacurium Intermediate acting Aminosteroid Vecuronium Rocuronium Benzylisoquinoline Atracurium Cisatracurium Sho acting Aminosteroid Rapacuronium Benzylisoquinoline Mivavcurium * Benzylisoquinoline group causes histamine release so IV injection of these drugs can cause hypotension,tachycardia, Bronchospasm, Flushing.