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What is Which of the following drug is alpha 2 agonist? and explain in detail?
Apraclonidine - Selective alpha 2 agonist. Useful in glaucoma. Alpha agonists (Brimonidine and apraclonidine) are contraindicated in hypeensive crisis. Dipivefrin is a prodrug which is conveed into epinephrine inside ttre eyeUall, so can safely be used in hypeension. REF : katzung pharmacology : 14th ed