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What is Cobalt poisoning and explain in detail?
Cobalt poisoning is intoxication caused by excessive levels of cobalt in the body. Cobalt is an essential element for health in animals in minute amounts as a component of Vitamin B12. A deficiency of cobalt, which is very rare, is also potentially lethal, leading to pernicious anemia.Exposure to cobalt metal dust is most common in the fabrication of tungsten carbide. Another source is from wear and tear of certain metal-on-metal hip prostheses.Per the International Agency for Research on Cancer (IARC), cobalt metal with tungsten carbide is "probably carcinogenic to humans" (IARC Group 2A Agent), whereas cobalt metal without tungsten carbide is "possibly carcinogenic to humans" (IARC Group 2B Agent).

Cobalt salts
The LD50 value for soluble cobalt salts has been estimated to be between 150 and 500 mg/kg. Thus, for a 100 kg person the LD50 would be about 20 grams.Soluble cobalt(II) salts are "possibly carcinogenic to humans" (IARC Group 2B Agents).

Beer drinkers cardiomyopathy
In August 1965, a person presented to a hospital in Quebec City with symptoms suggestive of alcoholic cardiomyopathy. Over the next eight months, fifty more cases with similar findings appeared in the same area with twenty of these being fatal