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What is In which of the following sites is Salmonella typhi most likely to be found during the carrier state? and explain in detail?
Salmonella typhi is the most likely to be found in gall bladder during the carrier state. Carriage: Up to 5% of patients become carriers. - The carrier state is more common in women than in men and in the older people (over 40 years) than in young people. - Carriers usually harbour the organisms in the gallbladder or biliary tract. - Type of Carriers:- Convalescent - shed bacilli for 3 weeks-3 months after clinical cure. Temporary - shed bacilli for 3 months to 1 year after clinical cure. Chronic - shed bacilli for more than 1 year. - Carriers can be diagnosed by stool/ urine culture or sewer swab culture. - Treatment of carriers: Ampicillin or Amoxicillin + probenecid for 6 months.