You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is 25/M presented with jaundice, clay coloured stool and pruritus. Bilirubin was 7gm%, Direct Bilirubin 5gm%, ALP 500 IU/L. Biopsy from biliary tract revealed the following. What is your diagnosis? and explain in detail?
Ans. (a) PSC* Clinical feature of jaundice, clay coloured stool and pruritus is suggestive of obstructive jaundice. Biopsy showing fibrotic obliteration of bile ducts ("onionskin" fibrosis) seen in primary biliary cirrhosis.