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What is Isolated rise in aPTT is seen in? and explain in detail?
Isolated rise of APTT are seen in APTT measures the activity of the intrinsic and common pathways of coagulation CAUSES Lupus anti-coagulant (anti-phospholipid syndrome) Heparin exposure Haemophilia A and B (Factor VIII and IX deficiency respectively) Factor XII deficiency Factor XI deficiency Contact factor deficiency e.g. pre-kallikrein (not clinically impoant) Aefactual (incorrect amount of blood in the tube) Ref Robbins 9/e pg 54