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What is A middle aged woman with history of backache underwent a Schober test and came as positive. She had hyperpigmented nose and ears. Looking at this radiograph, most likely diagnosis is:(AIIMS 2017) and explain in detail?
Ans. C OchronosisImage shows Intervertebral disc calcification commonly seen in alkaptonuria due to deposition of homogentisic acid. Schober's test is non-specific test that denotes loss of elasticity of spine. Hyperpigmented cartilage is another clue that points towards Alkaptonuria/Ochronosis.