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What is All of the following statements are true about quinidine except: and explain in detail?
(Ref: KDT 6/e p511, 512) Quinidine is a class I antiarrhythmic agent. It blocks Na+ channels in the open state and also delays the recovery of these channels. Blockade by these antiarrhythmic agents is frequency dependent. Class Ia antiarrhythmics, in addition blocks myocardial K+ channels also.