You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Feature of deficiency of the enzyme alkaline phosphatase: and explain in detail?
Hypophosphatasia is due to deficiency of enzyme alkaline phosphatase in serum or tissues and excretion of phosphoethanol amine in the urine.
Loosening and premature loss deciduous teeth. Chiefly the incisors, irregular qualifications of metaphyses of long bones are important features. The teeth characteristically shows absence of cementum as a result of failure of cementogenesis. So, there is no sound functional attachment of the tooth to bone by periodontal ligament and this accounts for early toss of deciduous teeth.