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What is Which of the following drugs can be safely prescribed in pregnancy? and explain in detail?
Ans. is 'c' i.e., Heparin Heparin does not cross the placenta because of its large molecular size; it is the anticoagulant of choice during pregnancy.About other options.WarfarinWhen used in early pregnancy, it causesSkeletal disorders (bossed forehead, sunken nose, foci of calcification in the epiphyses)Absence of the spleenACE inhibitorsFetal growth retardation, hypoplasia of organs and fetal death may occur if ACE inhibitors are given during later half of pregnancy.Not teratogenic in the first half Must be stopped when women conceives.b BlockersMay impair fetal response to hypoxia.