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What is Which of the following is a recently approved monoclonal antibody for treatment of Hemophilia A? and explain in detail?
EMICIZUMAB : Bispecific monoclonal antibody. Binds to both activated factors IX and X and helps in activation of factor X. This is normally the function of coagulation factor VIII, which is missing in haemophilia A patients Act like factor VIII so it is used for HEMOPHILIA A patients. SARILUMAB : MAB against IL -6 Used for Rheumatic ahritis ABALOPARATIDE : It is parathyroid related protein Used for Osteoporosis Injectable drug DURVALUMAB : MAB against PD ligand Used for urothelial carcinoma.