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What is Inodilation is and explain in detail?
(A) (Milrinone) (525-KDT 7th)1NODILATOR - Positive inotropy and direct vasodilation.Both preload and after load on the heart is reduced compared to dobutamine proportionately greater decrease in systemic vascular resistance in noted eg. Inamrinone (Amrinone/ Milrinone)Fasudil is an RhO - Kinase inhibitor involved in the vascular smooth muscle contractile response (ie angina with normal coronary arteries)Octreotide - somatostatin analogue uses - Vipoma, Insulinoma, Glucagonoma, Acromegaly, Acute bleeding of Gastrooesophageal varices, carcinoid tumours.Rotigotine - dopamine analogue that was approved for treatment of early Parkinson's disease in 2007 by FDA.Afixaban is factor Xa inhibitors (Anti coagulant action)