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What is Drug of choice in Theophylline poisoning? and explain in detail?
Ans. is 'd' i.e., Phenobarbitone Theophylline poisoning Theophylline has a narrow margine of safety. Dose dependent toxicity stas from the upper pa of therapeutic concentration range. Adverse effects are primarily referable to the GIT, CNS and CVS. Children are more liable to develop CNS toxicity. Treatment Prophylactic administration of diazepam in combination with phenytoin or phenobarbital. - Goodman & Gilman Ilth/e - 729 Lidocaine may be used for ventricular arrhythmia. Seizures refractory to anticonvulsant therapy, sometimes requiring general anaesthesia.