You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Vitamin B12 is required for a number of metabolic processes. Which of the following lesions would NOT lead to a deficiency of this vitamin? and explain in detail?
Absorption of vitamin B12 requires formation of a complex with intrinsic factor, which is secreted by parietal cells of the stomach. Destruction of these cells thus results in a vitamin B12 deficiency. The vitamin B12-intrinsic factor complex is absorbed in the ileum. Thus, surgical resection of the ileum, but not of the jejunum, will also produce a deficiency. Ref: Kaushansky K., Kipps T.J. (2011). Chapter 37. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In L.L. Brunton, B.A. Chabner, B.C. Knollmann (Eds), Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e.