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What is False about pseudomyxoma peritonei is: and explain in detail?
Pseudomyxoma peritonei: It is caused due to the rupture of mucinous adenocarcinoma. The most common primary tumor is appendix > ovary. It is the presence of jelly-like substance collected in the cavity and they are usually attached with other abdominal structures. Patient usually presents with abdominal distention, signs/symptoms of paial obstruction, weight loss and occurrence of sudden and multiple hernia (due to increased abdominal pressure) Diagnosis-by omental biospy Staging- PET CT Treatment is usually "Cytoreduction" which includes omentectomy+ peritonectomy+ right hemicolectomy + if female, bilateral salphingo-oophrectomy. If there is recurrence due to residual jelly-like substance after surgery, the treatment is Hypothermic Intra-peritoneal Chemotherapy (HIPEC) which as mitomycin C and cisplatin as impoant agents. Other agents are doxorubicin and docetaxel and these 4 agents are used as single drug or by combination.