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What is In congenital dystrophic variety of epidermolysis bullosa, mutation is seen in the gene coding for? and explain in detail?
In scarring dystrophic types, blisters developed beneath the lamina densa, in association with rudimentary or defective anchoring fibrils. Dystrophic epidermolysis bullosa is an inherited disease resulting from mutations in the COL 7A1 gene that encodes type 7 collagen Ref: Pathologic basis of disease (Robbins and cotran)7th edition, page no.1263