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What is Which of the following organelles plays a pivotal role in Apoptosis: and explain in detail?
Initiation of apoptosis occurs through two different pathways, intrinsic mitochondria pathway and extrinsic death receptor mediated pathway. Mitochondria plays active role in apoptosis. Ref: Tanley L. Robbins, Ramzi S. Cotran, (2012) , Chapter 1, "Cell Injury", In the book, "Pocket Companion to Robbins and Cotran Pathologic Basis of Disease", 8th Edition, USA, Page 27; Robbin's Basic Pathology, 7th Edition, Pages 28, 29; Essential of Apoptosis (2003), Page 245