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What is A diabetic and hypeensive patient taking several drugs presented with septicemia. Serum creatinine levels are 5.7 mg/dL. Which of the following drug should be stopped? and explain in detail?
Serum creatinine levels are raised indicating renal failure. In renal failure and hepatic failure --> Metformin is C/I as it |ses the risk of developing lactic acidosis. Contraindicated in patients with an eGFR below 30 mL/minute/1.73 m2. eGFR should be measured annually for patients taking metformin therapy. eGFR is preferred over serum creatinine concentration to assess renal function for a person taking metformin therapy Linagliptin is a DPP-4 inhibitor. Metoprolol is a b blocker.