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What is Kalli, 35yrs old female presents with Bilateral deep vein thrombosis in legs. There is past history of recurrent foetal loss and one attack of pulmonary embolism. Screening tests of coagulation reveal a prolonged aPTT. Likely diagnosis is: and explain in detail?
A female with history of deep vein thrombosis in legs, recurrent foetal loss and one attack of pulmonary embolism with prolonged aPTT highlights the diagnosis of a hypercoagulable state which is anti phospholipid syndrome. Ref: Hughes Syndrome: Antiphospholipid Syndrome By Munther A. Khamashta, 2006 ; Textbook of Obstetrics By Dutta, 6th Edition, Page 343 ; Williams Obstetrics, 21st Edition, Page 1390