You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Aschoff bodies in the myocardium are the hallmark of carditis associated with and explain in detail?
Acute rheumatic fever is characterized by discrete inflammatory foci within a variety of tissues. The myocardial inflammatory lesions--called Aschoff bodies--are pathognomonic for rheumatic fever these are collections of lymphocytes (primarily T cells), scattered plasma cells, and plump activated macrophages called Anitschkow cells occasionally punctuating zones of fibrinoid necrosis. The Anitschkow cells have abundant cytoplasm and central nuclei with chromatin condensed to form a slender, wavy ribbon (so-called caterpillar cells). During acute rheumatic fever, Aschoff bodies can be found in any of the three layers of the hea--pericardium, myocardium, or endocardium (including valves). Hence, rheumatic fever is said to cause pancarditis. (Robbins Basic pathology,9th edition.pg no.391)