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What is Which of the following is not an antiepileptic agent? and explain in detail?
Ans. is 'b' i.e., Flunarazine o Phenytoin, Topiramate and carbamezepine are antiepileptics,o Flunarizine is a Ca+2 channel blocker used for the prophylaxis of migraine.Mechanism of action of different antiepiiepticsProlongation of Na+ channel inactivationo Phenytoino Carbamazepineo Valproateo Lamotrigineo Topiramateo ZonisamideFacilitation of GABA mediated Cl- channel openingo Barbiturateso Benzodiazepineo Vigabatrino Valproateo Gabapentino TiagabineInhibition of T type Ca++ currento Ethosuximideo Trimethadioneo ValproateDecrease of excitatory neurotransmissiono Felbamale (Katzung 10th/e 382)