You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Fulminant hepatitis E is seen in? and explain in detail?
ANSWER: (A) Pregnant womenREF: Park 18th ed p. 174, Robbins 7th ed 891 table 18-6Important points about hepatitis E:Transmitted by feco-oral routeFulminant hepatitis E seen in pregnant women (20-40%) especially in last trimesterMost common cause opf sporadic cases of hepatitis in adults - Hepatitis EEpidemics are almost exclusively caused by enetrically transmitted Hepatitis E Hepatitis AHepatitis BHepatitis CHepatitis DHepatitis EHepatitis GAgentIcosahedral capsid, ssRNAEevelopeddsDNAEnvelopedssRNAEnvelopedssRNANon enveloped ssRNAssRNATrans-missionFecal oralParenteral, dose contactParenteral, close contactParenteral, close contactWaterborneParenteralIncubationperiod2-6 wks4-26 wks2-26 wks4-7 wks2-8 wksUnknownCarrier stateNone0.1-1% of blood donors in U.S & west0.2-1% of blood donors in U.S & west1-10% in drug addicts & hemophiliacUnknown1-2% of blood donors in U.SChronic hepatitisNone5-10% of acute infections>50%< 5% coinfection, 80% upon super infectionNoneNoneHepato-cellularcarcinomaNoYesYesNo increase above HBVUnknown but unlikelyNone