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What is Alcohol is metabolized by ? and explain in detail?
Ethyl alcohol (ethanol) is readily absorbed from GIT and degraded by oxidation (oxidative process).Liver is the major site for ethanol oxidation.At least three enzyme systems are capable of ethanol oxidation :-i) Alcohol dehydrogenase (ADH) - Major pathwayii) Microsomal ethanol oxidising system (MEOS) : It involves cytochrome P450.iii) Catalase of peroxisomes.The product of all three oxidation pathways is acetaldehyde, which is rapidly oxidized to acetate by aldehyde dehydrogenase (ALDH).