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What is Excess dietary intake of carbohydrates increases the RDA level of: and explain in detail?
Thiamine is needed for only 4 enzymes in the body.They are:- Pyruvate dehydrogenase a keto glutarate dehydrogenase Transketolase Branched chain ketoacid dehydrogenase. Branched chain ketoacid dehydrogenase is involved in the metabolism of amino acids Rest all the 3 enzymes are involved in carbohydrate metabolism. So, increased carbohydrate intake increases the requirement of thiamine also. Transketolase enzyme estimation is used in thiamine deficiency