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What is Gemfibrozil is:- and explain in detail?
Gemfibrozil: MOA: Activation of the nuclear transcription receptor "peroxisome proliferator - activated receptor alpha" (PPAR-a). Major effects are to increase plasma HDL and to decrease plasma TG. Myopathy risk highest when used with statins Statins: Inhibit HMG COA reductase Inhibit cholesterol synthesis. EZETIMIBE- Inhibit intestinal cholesterol absorption.