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What is All the following factors predispose to Aoic dissection , except and explain in detail?
Ref Harrison 19 th ed pg 1541 Aoic dissection is the major cause of morbidity and moality in patients with Marfan's syndrome or Loeys- Dietz syndrome, and similarly may affect patients with Ehlers-Danlos syndrome. The incidence also is increased in patients with inflamma- tory aoitis (i.e., Takayasu's aeritis, giant cell aeritis), congenital aoic valve anomalies (e.g., bicuspid valve), coarctation of the aoa, and a history of aoic trauma. In addition, the risk of dissection is increased in otherwise normal women during the third trimester of pregnancy. Aoic dissection also may occur as a consequence of weight lifting, cocaine use, or deceleration injury.