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What is Aspirin should be used with caution in the following groups of patients because of which of the following reason: and explain in detail?
Aspirin- Urate excretion: Aspirin in high dose reduces renal tubular excretion of urate- dose more than 5 grams per day- that is more than the antiinflammatory dose ESSENTIALS OF MEDICAL PHARMACOLOGY;7TH EDITION; KD TRIPATHI; PAGE NO 195