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What is Giant papillary conjunctivitis is associated with: and explain in detail?
Ref: Kanski Clinical Ophthalmology 6th edition; page no 218. 234Explanation:Conjunctival papillae: Hyperplasic conjunctivalepithelium with fibrovascular core & subepithelial infiltration w ith inflammatory cells Thi 'ee types of papillae: Micropapillae - mosaic like red dotsMacropapillae - < 1mm in size Giant papillae - > I mm in size Causes of (iiant papillary conjunctivitisRepeated mechanical irritation of the conjunctivaOcular prosthesesExtruding scleral bucklesExposed ocular suturesFiltering blebElevated corneal scars- Giant papillary conjunctivitis symptoms and signs, such as papillary changes in the tarsal conjunctiva, have been associated w ith the use of all types of contact lenses (eg, rigid, hydrogel* silicone hydrogel, piggyback, scleral, prosthetic).Incidence of giant papillary conjunctivitis with various type of contact lensesSoft contact lens wearers: 1% to 45%.Conventional soft contact lens: 34%Extended wear disposable soft contact lens wearers -5%Frequent replacement contact lens (every one day to twrelve weeks): 21.27%Rigid gas permeable lens wearers: Very low (1 % to 5% ).TYPESSITECAUSESAnteriorInvolving part of the whole of the cornea; lined by irisSloughing corneal ulcerIntercalaryLimbus & 2mm from the limbus; lined by ciliary bodyPerforating injuries, marginal corneal ulcer, anterior scleritis, scleromalacia perforans, post surgical wound site, secondary glaucomaEquatorial2-8 mm from the 1mbus ; lined bv the choroidScleritis. pathological myopia, chronic uncontrolled glaucomaPosteriorPosterior pole; lined by the choroidSame as equatorial