You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which of the following represents the mechanism of action of Eternacept? and explain in detail?
Etanercept is a fusion protein of TNFRII and the Fc region of IgG1, that binds to TNF and prevent the molecule from interacting with its two receptors, TNFRI and TNFRII, thereby stopping signaling events. TNF is involved in inflammatory and immune responses. Etanercept can also modulate biologic responses regulated by TNF. Ref: Handbook of Dermatologic Drug Therapy By Steven R. Feldma, Page 76