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What is A 1-month-old child presented with bullous lesions at the sites of friction like knees, elbows and fingers. The blisters were hemorrhagic and healed with scarring and milia formation. Nail involvement was seen with sparing of mucosa. Biopsy of the lesion was also taken Which of the following structures is most likely to be involved: - and explain in detail?
THIS IS A CLASSICAL CASE OF AD EPIDERMOLYSIS BULLOSA DYSTROPHICA. Biopsy reveals a sub-epidermal bulla - suggestive of AD epidermolysis bullosa dystrophica. DISEASE EB SIMPLEX (MOST COMMON) DYSTROPHIC EB JUNCTIONAL EB BLISTERS IN EPIDERMIS IN DERMIS B/W DERMIS AND EPIDERMIS MUTATIONS K 5 OR K 14 COL7A1 LAMA3, LAMB3