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What is A 7-year-old girl is brought with complaints of generalized swelling of the body. Urinary examination reveals grade 3 proteinuria and the presence of hyaline and fatty casts. She has no history of hematuria. Which of the following statements about her condition is true? and explain in detail?
Grade 3 proteinuria, and the presence of hyaline and fatty cast in urine suggest the diagnosis of nephrotic syndrome.
Most common cause of nephrotic syndrome in a child is minimal change disease ( not IgA nephropathy or Alport syndrome)
In minimal change disease there is no deposition of immune reactants (immunoglobulin or complement), and serum complement levels are normal.