You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Which of the following is the rate limiting enzyme in glycogenesis? and explain in detail?
Glycogen synthase catalyzes the formation of a glycoside bond between C-1 of the glucose of UDPGlc and C-4 of a terminal glucose residue of glycogen, liberating uridine diphosphate (UDP).
The principal enzymes controlling glycogen metabolism glycogen phosphorylase and glycogen synthase—are regulated in opposite directions by allosteric mechanisms and  covalent modification by reversible phosphorylation and dephosphorylation of enzyme protein in response to hormone action.

Rate Limiting Steps

Glycogenesis: Glycogen synthase.
Glycogenolysis: Glycogen phosphorylase.

Harper 30th edition Pg-179,175