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What is Drug causing hypokalemia is: and explain in detail?
Drugs causing hypokalemia-furosemide, amphotericin B, salbutamol, cisplatin, hydrochlorothiazide Amphotericin B: Acute reaction of amphotericin B excess- symptoms include chills, fever, aches, pain, nausea, vomiting, and dyspnoea lasting for 2-5 hours due to the release of cytokines (IL, TNF alpha). Injection of hydrocoisone 0.6 mg/kg with the infusion may reduce the intensity of reaction. Thrombophlebitis of the injected vein can occur. Long term toxicity Nephrotoxicity is the most Impoant. Dose-related manifestations are--azotemia, reduced g. r. f acidosis, hypokalaemia and inability to concentrate urine. It reverses slowly and often incompletely after stoppage of therapy . ESSENTIALS of medical PHARMACOLOGY SIXTH EDITION-KD TRIPATHI Page:757,758