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What is Which one of the following drugs does not have active metabolite ? and explain in detail?
- Among the given options, only Lisinopril does not have an active metabolite. Except for Captopril and Lisinopril, all Angiotensin Converting Enzyme (ACE) inhibitors are prodrugs.
- Diazepam produces Oxazepam and many other active metabolites.
- Propranolol can give rise to 4-hydroxyPropranolol which has β antagonist activity
- Oxypurinol is produced from Allopurinol.