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What is Minimum inhibitory concentration is ? and explain in detail?
Ans. is 'c' i.e., Minimum concentration of an antibiotic which prevents visible growth of a bacterium Antimicrobial sensitivity To estabilish the activity of an antimicrobial agent, microrganisms are tested for their ability to grow in the presence of suitable concentration of drug. Methods used are ? 1. Disc diffusion method 2. Broth culture with break point Potency of antimicrobial agents is often referred as M1C. 1. Minimum inhibitory concentration (MIC) Lowest concentration of an antibiotic which prevents visible growth of a bacterium. 2. Minimum bactericidal concentration (MBC) The concentration of an antibiotic which kills 99.9% of the bacteria. 3. A small difference between MIC and MBC indicates that the antibiotic is primarily bactericidal, while a large difference indicates bacteriostatic action.