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What is Which of the following statement regarding gas gangrene is TRUE? and explain in detail?
Gas gangrene is a rapidly developing and a spreading infection caused by the toxin producing clostridial species namely, Clostridium perfringens ( formerly known as C. welchii). It is highly fatal if left untreated and accompanied by profound toxicity. If the oxidation-reduction potential in a wound is sufficiently low, C perfringens spores can germinate and then multiply, elaborating alpha-toxin. The process passes along the muscle bundles, producing rapidly spreading edema and necrosis as well as conditions that are more orable for growth of the bacteria. As the disease progresses, increased vascular permeability and systemic absorption of the toxin and inflammatory mediators leads to shock. Ref: Oxford Textbook of Medicine, Vol 1 By D. A. Warell, Timothy M. Cox, Page 553