You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is IL - I produces - and explain in detail?
Interleukin -1 

Also known as leucocyte activating factor (LAF) or B cell activating factor (BAF).


Principally secreted by macrophages and monocytes, and epithelial cells.
Other sources are B lymphocytes, fibroblasts and endothelial cells.
Immunological effects-

- Activation of T cells for the production of IL - 2.
- B cell proliferation and antibody synthesis
- Neutrophil chemotaxis and increased PMN release from bone marrow.
- Increases body temperature (important endogenous pyrogen).
- Bone marrow cell proliferation
- Induction of acute phase protein.