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What is Hepatitis B infection persists in 3% asymptomatic individuals. Why is there an increased risk of developing liver cancer in these patients? and explain in detail?
Hepatocellular carcinoma and HBV Hepatis B is am impoant risk factor for HCC HBV persists in 3% of asymptomatic patients. But at increased risk of developing Liver cancer because of Integration of viral DNA to host DNA- Inhibition of apoptosis -Hepato-cellular carcinoma =High rate of hepatocyte proliferation- Refers to high infectivity of the virus so basically higher chances of infection but not cancer. =Inability to induce inflammation to remove organism -Explains for carrier stage