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What is Investigation of choice for meningeal carcinomatosis in CNS: and explain in detail?
D i.e. Gd-MRI Investigation of choice for meningeal carcinomatosis is Gd enhanced MRIQ (especially for detection of focal spread, bulky disease and metastases from solid tumor). Demonstration of tumor cells/tumor markers in CSF is definitive & often considered gold standard; but has suboptimal/moderate overall sensitivity, and is more sensitive in detecting diffuse leptomeningeal involvement from hematological malignancy