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What is Side effect seen with cisplatin: and explain in detail?
Ans. A. Nausea/vomitingCisplatin is highly emetogenic drug. It directly stimulates the CTZ area. Treatment of choice for this toxicity is ondansetron. Methotrexate is highly nephrotoxic. Busulfan and bleomycin are known to cause pulmonary fibrosis. Bone marrow suppression is side effect which is commonly seen with all the anticancer drugs.