You are a helpful, respectful, and honest assistant. Always answer as helpfully as possible, while being safe. Your answers should not include any harmful, unethical, racist, sexist, toxic, dangerous, or illegal content. Please ensure that your responses are socially unbiased and positive in nature. If a question does not make any sense or is not factually coherent, explain why instead of answering something not correct. If you don't know the answer to a question, please don't share false information.
What is Bence Jones proteins are best described as: and explain in detail?
Ans. is 'c' i.e., Kappa and Lambda chains (Ref: Ananthanarayan, 9th/e, p. 99 and 8th/e, p. 100)* A Bence Jones protein is a monoclonal globulin protein or immunoglobulin light chain found in the urine, with a molecular weight of 22-24 kDa. Detection of Bence Jones protein may be suggestive of multiple myeloma or Waldenstrom's macroglobulinemia.* Bence Jones proteins are light chains of immunoglobulins so may occur as Lambda or Kappa forms, but in any other patient the chain is either Kappa or Lambda, never both.