effects such as burning, redness, pain, and a foreign body sensation. For contact lens users, specific drops should be used to avoid ingredients that can damage the contact lens. If using multiple types of eye drops, it is important to wait a few minutes in between application of each to avoid rinsing out the prior drop. Proper technique should be conducted to avoid contaminating the bottle. Washing hands prior to use and avoiding contact between the bottle and eyes can prevent infections. Veterinary uses Artificial tears are a part of the topical therapy for keratoconjunctivitis sicca for animals such as dogs, cats and horses. Similarly to human use, proper care should be performed to avoid contamination of the bottle. A veterinarian should be contacted if any signs of allergy, irritation, or pain develop due to the usage of artificial tears. Research A 2016 Cochrane Review seeking to compare the effectiveness of various over the counter artificial tears in treating dry eye. While the review stated that it is unclear which artificial tear formulation works best, two trials found that 0.2% polyacrylic acid-based tears were more effective in treating dry eye symptoms over 1.4% polyvinyl alcohol-based tears. 2023 recall On February 2, 2023, Global Pharma Healthcare issued a recall on artificial tears eye drops distributed by EzriCare and Delsam Pharma after reports of bacterial contamination. A multi-state cluster of Verona Integron-mediated Metallo-β-lactamase (VIM)- and Guiana-Extended Spectrum-β-Lactamase (GES)- producing carbapenem-resistant Pseudomonas aeruginosa (VIM-GES-CRPA) infections from the contaminated eye drops has led to reports of eye infections, permanent loss of vision, and one death. See also Sjögren's syndrome References External links Use of preservatives in artificial tears Ophthalmology drugs Electrolyte disturbances Dog medications Cat medications Equine medications