on the northwest corner of Lexington Avenue and 42nd Street (Manhattan), opening May 1, 1870. The building had a fire-proof staircase and an elevator run by a steam-engine. There was no operating room until 1888 after a hospital fire. At the turn of the century, it became the target for efforts to expand Grand Central Terminal and negotiations were led by Cornelius Vanderbilt, II, a member of the Board of Managers of the hospital. In 1912, the hospital moved to a six-story building on 42nd Street between First Avenue and Second Avenue, a site that is now the home of the Ford Foundation. The hospital moved to its present location in 1955. About Research Current clinical trials focus on issues related to lupus and arthritis. In addition to clinical trials, HSS has several research programs that center on the prevention of musculoskeletal diseases. Basic and applied research conducted at the hospital addresses specific problems such as arthritis, injury, osteoporosis, scoliosis, autoimmune diseases such as lupus, and related musculoskeletal diseases as they affect children and adults. Affiliations The Hospital for Special Surgery is affiliated with the NewYork-Presbyterian Healthcare System through the hospital's affiliation with Weill Cornell Medical College. The hospital is also affiliated with Memorial Sloan-Kettering Cancer Center, and Rockefeller University. Facilities Located on the Upper East Side of Manhattan, HSS is built over the Franklin D. Roosevelt (FDR) drive and partially located in the Belaire building at 535 East 70th Street. Currently HSS has 205 beds and 29 operating rooms. HSS recently completed the construction of a new, ninth floor that adds of new space and of re-engineered and re-designed space. HSS has several specialized centers that focus on specific patients and joint problems, including: Institute for Cartilage Repair Children and Adolescent Hand and Arm (CHArm) Center Foster Center for Clinical Outcome Research Computer Assisted Surgery (CAS) Center Center for Hip Pain and Preservation Gosden Robinson Inflammatory Arthritis Center Integrative Care Center - Combining traditional medicine (Physiatry, with inter alia Chiropractic and Acupuncture) Institute for Limb Lengthening and Complex Reconstruction Mary Kirkland Center for Lupus Care Mary Kirkland Center for Lupus Research Musculoskeletal Magnetic Resonance Imaging Center The Center for Musculoskeletal Ultrasound and Nuclear Medicine Orthopedic Trauma Service Osteoporosis Prevention Center The Kathryn O. and Alan C. Greenberg Center for Skeletal Dysplasias Spine Care Institute Barbara Volcker Center for Women and Rheumatic Disease Women's Sports Medicine Center Notable alumni Notable