Propargyl substituted bislactim ethyl ether is generated by using Schöllkopf chiral auxiliary bis lactam ether with n-BuLi, THF, and 3-halo-1-9trimethylsily1)-1-propyne and extracting the trans-isomer of the propargyl-substituted bislactim. Other relevant applications include the synthesis of 5-HT1D receptor agonist MK-0462, an anti-migraine drug. References Indole forming reactions Name reactions