Menopause The Musical is a 2001 musical with book and lyrics by Jeanie Linders which premiered on March 28, 2001 in Orlando, Florida. The musical follows four mature women shopping for lingerie at a Bloomingdale's sale, with lyrics parodying popular music from the baby boomer era to reflect symptoms of the menopause. Following the success of an Off-Broadway production, running for over 1,500 performances until 2006, the show was produced across the United States touring to the present day including in Las Vegas, where it has been running since 2006 as the longest running scripted musical in Las Vegas history. The show has spawned productions worldwide. Productions Original Orlando production The original Orlando production opened on March 28, 2001 at the Church Street Theatre building, that was specifically converted from a perfume shop into a 76-seat theatre for the show. Its original cast members were Shelly Browne as the Power Woman (later renamed the Professional Woman), Patti McGuire as the Iowa Housewife, Pammie O'Bannon as the Earth Mother, and Wesley Williams as the Soap Star. The show then transferred to West Palm Beach's Cuillo Center on June 22, 2001. Original off-Broadway productions The Off-Broadway production officially opened at Theatre Four on April 4, 2002, after a month of previews. It then transferred to Playhouse 91 in September of that year. After running for four years, the Off-Broadway production closed in May 2006. North American productions Alongside the New York and Florida runs, GFour Productions mounted further sit-down productions throughout the United States. These opened at the Apollo Theatre in Chicago on July 25, 2003, becoming the highest grossing musical in the theatre's history after 1,281 performances, the Coronet Theatre in Los Angeles on October 30, 2003, the Gem Theatre in Detroit on March 17, 2004 becoming the longest running show in Michigan's history and the Stuart Street Playhouse in Boston on March 31, 2004 running for 1,092 performances. The Las Vegas production has been running continuously since 2006, currently at Harrah's Las Vegas. This was followed by a national tour that continues to run to this day, reaching over 500 cities worldwide. A further American tour specifically to raise funds and awareness for the fight against ovarian cancer was later launched in 2015. International productions International productions have been staged all over the world. Local references in the show are customized to the location of the performance. For example, the