standard-less, depth-resolved and highly accurate elemental composition analysis in the depth regime from several nm up to few μm. By changing type of incident ion, the geometry of experiment, particle energy, or by acquiring different products originating from ion-solid interaction, complementary information can be extracted. However, analysis is often challenged either in terms of mass resolution - when several comparably heavy elements are present in the sample - or in terms of sensitivity - when light species are present in heavy matrices. Hence, typically only a combination of several ion beam-based techniques will overcome the limitations of each individual method and provides complementary information about the sample. The combination of several IBA techniques (RBS, EBS, PIXE, ERD) in an iterative and self-consistent analysis prove to enhance the accuracy of the information that can be obtained from each independent measurement. Software and simulation Dating back to the 1960s the data collected via ion beam analysis has been analyzed through a multitude of computer simulation programs. Researchers who frequently use ion beam analysis in conjunction with their work require that this software be accurate and appropriate for describing the analytical process they are observing. Applications of these software programs range from data analysis to theoretical simulations and modeling based on assumptions about the atomic data, mathematics and physics properties that detail the process in question. As the purpose and implementation of ion beam analysis has changed over the years, so has the software and codes used to model it. Such changes are detailed through the five classes by which the updated software are categorized. Class-A Includes all programs developed in the late 1960s and early 1970s. This class of software solved specific problems in the data; niy did not provide the full potential to analyze a spectrum of a full general case. The prominent pioneering program was IBA, developed by Ziegler and Baglin in 1971. At the time, the computational models only tackled the analysis associated with the back-scattering techniques of ion beam analysis and performed calculation based on a slab analysis. A variety of other programs arose during this time, such as RBSFIT, though due to the lack of in-depth knowledge on ion beam analysis, it became increasingly hard to develop programs that accurate. Class-B A new wave of programs sought to solve this accuracy problem in this next class of software. Developed during the 1980s, programs like SQEAKIE and BEAM