BioMCQA/test_mcq · Datasets at Hugging Face

question_key stringlengths 16 58	relation stringlengths 6 48	question_template stringlengths 29 90	subject_cui stringlengths 8 8	subject_label stringlengths 4 160	correct_object_cui stringlengths 8 8	correct_object_label stringlengths 3 204	opa stringlengths 7 150	opb stringlengths 3 204	opc stringlengths 4 221	opd stringlengths 5 166	cop int64 0 3
C2981613::disease_excludes_finding	disease_excludes_finding	Which finding is specifically excluded in the diagnosis of disease {subj}?	C2981613	Stage IIIA Digestive System Neuroendocrine Tumor AJCC v7	C0333868	Severe cytologic atypia	Neurofibrillary degeneration (morphologic abnormality)	Trisomy 18 (morphologic abnormality)	Severe cytologic atypia	Squamous metaplasia	2
C5420536::disease_excludes_finding	disease_excludes_finding	Which finding is specifically excluded in the diagnosis of disease {subj}?	C5420536	Advanced Cervical Adenosquamous Carcinoma	C0277565	Local disease	Regional enteritis	Basal pneumonia	Local disease	Nodal block	2
C4725707::disease_excludes_normal_cell_origin	disease_excludes_normal_cell_origin	Which normal cell origin is specifically excluded in the disease {subj}?	C4725707	Extracavitary Primary Effusion Lymphoma	C0032112	Plasma Cells	Phagocytes	Cells.HLA-B27	Plasma Cells	Plasma cells.abnormal marker pattern	2
C0079773::disease_excludes_normal_cell_origin	disease_excludes_normal_cell_origin	Which normal cell origin is specifically excluded in the disease {subj}?	C0079773	Lymphoma, T-Cell, Cutaneous	C0887899	Myeloid Cells	Myeloid precursor cell	Myeloid Cells	Pre-B Lymphocytes	Blood Cells	1
C5855556::disease_excludes_normal_cell_origin	disease_excludes_normal_cell_origin	Which normal cell origin is specifically excluded in the disease {subj}?	C5855556	IgM Monoclonal Gammopathy of Undetermined Significance, Plasma Cell Type	C1516097	B lymphoblast	Monocytoid B-Lymphocyte	CYIG+ lymphocyte	B lymphoblast	Activated B-Lymphocyte	2
C1335388::disease_excludes_normal_tissue_origin	disease_excludes_normal_tissue_origin	Which normal tissue origin is specifically excluded in the disease {subj}?	C1335388	Peripheral Intraneural Angiosarcoma	C0014609	Epithelium	Entire respiratory epithelium	Bile Duct Epithelium	Epidermis	Epithelium	3
C5554988::disease_excludes_normal_tissue_origin	disease_excludes_normal_tissue_origin	Which normal tissue origin is specifically excluded in the disease {subj}?	C5554988	Unresectable Myxofibrosarcoma	C0014609	Epithelium	Epithelium	Epidermis proper	Epidermal Ridge	Transitional epithelium	0
C0206717::disease_excludes_normal_tissue_origin	disease_excludes_normal_tissue_origin	Which normal tissue origin is specifically excluded in the disease {subj}?	C0206717	Olfactory Neuroblastoma	C1708239	Germinal Layer	Structure of germinal epithelium of ovary	Basal Domain of the Epithelium	Peyer Patch Germinal Center	Germinal Layer	3
C4520724::disease_excludes_primary_anatomic_site	disease_excludes_primary_anatomic_site	Which primary anatomic site is specifically excluded in the disease {subj}?	C4520724	Stage III Adult Soft Tissue Sarcoma AJCC v7	C0262950	Skeletal bone	Skeletal muscle structure of head	Skeleton of forearm	Skeletal bone	Bone structure of forearm	2
C1332903::disease_excludes_primary_anatomic_site	disease_excludes_primary_anatomic_site	Which primary anatomic site is specifically excluded in the disease {subj}?	C1332903	Cerebellar Vermis Medulloblastoma	C0037925	Spinal Cord	Spinal cord posterior horn	Spinal nerve root NEC	Spinal Cord	Spinal cord tissue structure	2
C1516417::disease_excludes_primary_anatomic_site	disease_excludes_primary_anatomic_site	Which primary anatomic site is specifically excluded in the disease {subj}?	C1516417	Cervical Large Cell Neuroendocrine Carcinoma	C0460004	Head and neck structure	External nose structure	Chest and abdominal vessels	Upper jaw region	Head and neck structure	3
C5206840::disease_has_abnormal_cell	disease_has_abnormal_cell	Which abnormal cell type is characteristic of the disease {subj}?	C5206840	Unresectable Oropharyngeal Squamous Cell Carcinoma	C1514101	Neoplastic Squamous Cell	Neoplastic Cell	Primitive neuroblastic cell	Lymphosarcoma cell	Neoplastic Squamous Cell	3
C2212014::disease_has_abnormal_cell	disease_has_abnormal_cell	Which abnormal cell type is characteristic of the disease {subj}?	C2212014	Ovarian Mucinous Adenocarcinofibroma	C0334227	Tumor cells, malignant	Entire endometrial glandular cell	Tumor cells, malignant	Vacuolated Malignant Fibroblast	Neoplastic Polygonal Cell	1
C2825773::disease_has_abnormal_cell	disease_has_abnormal_cell	Which abnormal cell type is characteristic of the disease {subj}?	C2825773	Malignant Epithelioid Cell Type Gastrointestinal Stromal Tumor	C1514104	Neoplastic Stromal Cell	Endocrine-Stromal Cell	Primitive neuroblastic cell	Neoplastic Epithelial Polygonal Cell	Neoplastic Stromal Cell	3
C2347926::disease_has_associated_anatomic_site	disease_has_associated_anatomic_site	Which anatomic site is associated with the disease {subj}?	C2347926	Refractory Spinal Cord Neoplasm	C0037925	Spinal Cord	Spinal nerve root S1	Spinal Cord	Spinal cord posterior horn	Cervical Spinal Nerve Root	1
C0033375::disease_has_associated_anatomic_site	disease_has_associated_anatomic_site	Which anatomic site is associated with the disease {subj}?	C0033375	Prolactinoma	C0149543	Base of skull structure	Base of skull structure	Orbital complex of bones - floor	Base of cochlear canal	Base of cochlear duct	0
C1520094::disease_has_associated_anatomic_site	disease_has_associated_anatomic_site	Which anatomic site is associated with the disease {subj}?	C1520094	Vulvar Sebaceous Carcinoma	C1261210	Reproductive system	Reproductive system	Skeletal system	Arterial system	Digestive system subdivision	0
C0279748::disease_has_associated_disease	disease_has_associated_disease	Which other disease is associated with the disease {subj}?	C0279748	Undifferentiated carcinoma of nasopharynx	C0042769	Virus Diseases	B Virus Infection	Flavivirus Infections	Virus Diseases	Coronaviridae Infections	2
C1335509::disease_has_associated_disease	disease_has_associated_disease	Which other disease is associated with the disease {subj}?	C1335509	Prostate Kaposi Sarcoma	C0042769	Virus Diseases	B Virus Infection	Filoviridae Infections	Virus Diseases	Pestivirus Infections	2
C2986686::disease_has_associated_disease	disease_has_associated_disease	Which other disease is associated with the disease {subj}?	C2986686	Ann Arbor Stage IV AIDS-Related Lymphoma	C0009450	Communicable Diseases	Immune System Diseases	Opportunistic Infections	Communicable Diseases	Pneumonia in bacterial diseases classified elsewhere	2
C0302592::disease_has_associated_gene	disease_has_associated_gene	Which gene is associated with the disease {subj}?	C0302592	Cervix carcinoma	C2826017	MIR218-1 wt Allele	MIR218-1 wt Allele	MIR373 wt Allele	MIR191 wt Allele	MIR135B wt Allele	0
C0279628::disease_has_associated_gene	disease_has_associated_gene	Which gene is associated with the disease {subj}?	C0279628	Adenocarcinoma Of Esophagus	C1332804	CTSB gene	LTB gene	CTSB gene	SPIB gene	CTNS gene	1
C0002395::disease_has_associated_gene	disease_has_associated_gene	Which gene is associated with the disease {subj}?	C0002395	Alzheimer's Disease	C1705380	ZFYVE9 wt Allele	WDFY2 wt Allele	SIGLEC9 wt Allele	ARHGEF10 wt Allele	ZFYVE9 wt Allele	3
C5238468::disease_has_finding	disease_has_finding	Which finding is characteristic of the disease {subj}?	C5238468	Locally Advanced Neuroendocrine Neoplasm	C0277565	Local disease	Disseminated scars	Burn shock	Local disease	Bone destruction	2
C4764032::disease_has_finding	disease_has_finding	Which finding is characteristic of the disease {subj}?	C4764032	Recurrent B-Cell Prolymphocytic Leukemia	C0277556	Recurrent disease	Recurrent phimosis	Recurrent disease	Recurrent infections, mild	Relapsing Fever	1
C1335035::disease_has_finding	disease_has_finding	Which finding is characteristic of the disease {subj}?	C1335035	Non-Destructive Post-Transplant Lymphoproliferative Disorder	C0021051	Immunologic Deficiency Syndromes	Immunologic Deficiency Syndromes	Hyper-IgM Immunodeficiency Syndrome, Type 1	Simian Acquired Immunodeficiency Syndrome	Immune System Diseases	0
C0677689::disease_has_molecular_abnormality	disease_has_molecular_abnormality	Which molecular abnormality is characteristic of the disease {subj}?	C0677689	Ann Arbor Stage II Grade 3 Contiguous Follicular Lymphoma	C1516672	Clonal Immunoglobulin Gene Rearrangement	Absence of Biallelic TCRgamma Deletion	Clonal Immunoglobulin Gene Rearrangement	FEV Gene Rearrangement	IGH Gene Rearrangement	1
C5670614::disease_has_molecular_abnormality	disease_has_molecular_abnormality	Which molecular abnormality is characteristic of the disease {subj}?	C5670614	Embryonal Tumor with Multilayered Rosettes, DICER1-Mutated	C4528702	DICER1 Gene Mutation	Deleterious DICER1 Gene Mutation	DICER1 Gene Mutation	DOT1L Gene Mutation	DIS3 Gene Mutation	1
C0281700::disease_has_molecular_abnormality	disease_has_molecular_abnormality	Which molecular abnormality is characteristic of the disease {subj}?	C0281700	Stage I Childhood Burkitt Lymphoma	C1516673	Clonal Immunoglobulin Heavy Chain Gene Rearrangement	Absence of Biallelic TCRgamma Deletion	IGK Gene Rearrangement	T-Cell Receptor Gene Rearrangement	Clonal Immunoglobulin Heavy Chain Gene Rearrangement	3
C5669728::disease_has_normal_cell_origin	disease_has_normal_cell_origin	From which normal cell type does the disease {subj} originate?	C5669728	Extramedullary Disease in Multiple Myeloma Involving the Skin	C1511241	Bone Marrow-Homing Plasma Cell	Bone Marrow-Homing Plasma Cell	Mobilized Peripheral Blood Stem Cell	Neoplastic Medium-Sized Lymphocyte	Neoplastic Small to Medium-Sized B-Lymphocyte Resembling a Centrocyte	0
C4682696::disease_has_normal_cell_origin	disease_has_normal_cell_origin	From which normal cell type does the disease {subj} originate?	C4682696	Stage IIB Penile Cancer AJCC v8	C0014597	Epithelial Cells	Ciliated epithelial cell	Epithelial Cells	Endocrine Cells	Malignant Myoepithelial Cell	1
C5855486::disease_has_normal_cell_origin	disease_has_normal_cell_origin	From which normal cell type does the disease {subj} originate?	C5855486	B Acute Lymphoblastic Leukemia with HLF Rearrangement	C0024264	Lymphocyte	CD105+ lymphocyte	HLE+ lymphocyte	Lymphocyte	B-Lymphocytes, Regulatory	2
C3146256::disease_has_normal_tissue_origin	disease_has_normal_tissue_origin	From which normal tissue does the disease {subj} originate?	C3146256	Stage II Rectal Cancer AJCC v7	C0014609	Epithelium	Oral epithelium tissue specimen	Stratified squamous epithelium	Epidermal basement zone	Epithelium	3
C4727196::disease_has_normal_tissue_origin	disease_has_normal_tissue_origin	From which normal tissue does the disease {subj} originate?	C4727196	Recurrent Gastroesophageal Junction Adenocarcinoma	C0014609	Epithelium	Endothelium	Epidermal Ridge	Epithelium	Ductal Epithelium	2
C1292772::disease_has_normal_tissue_origin	disease_has_normal_tissue_origin	From which normal tissue does the disease {subj} originate?	C1292772	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	C0229619	Hemopoietic tissue	All bone marrow of bone organ	Hemopoietic tissue	Entire transplanted bone marrow	Genitourinary lymphoid tissue	1
C4763829::disease_has_primary_anatomic_site	disease_has_primary_anatomic_site	What is the primary anatomic site of the disease {subj}?	C4763829	Metastatic Bladder Plasmacytoid Urothelial Carcinoma	C1508753	Urinary system	Skeletal system.peripheral	Articular system	Urinary system	Entire genitourinary system	2
C1710249::disease_has_primary_anatomic_site	disease_has_primary_anatomic_site	What is the primary anatomic site of the disease {subj}?	C1710249	Superficial Epithelioma with Sebaceous Differentiation	C0036505	Sebaceous Glands	Duct of sebaceous gland	Sebaceous Glands	Sebaceous lobule	Sebaceous gland of areola	1
C3899978::disease_has_primary_anatomic_site	disease_has_primary_anatomic_site	What is the primary anatomic site of the disease {subj}?	C3899978	BCLC Stage C Adult Hepatocellular Carcinoma	C0012240	Gastrointestinal system	Respiratory system subdivision	Upper digestive tract NEC	Gastrointestinal system	Entire digestive system	2
C4553846::disease_is_stage	disease_is_stage	For which disease is {subj} a stage?	C4553846	Stage IV Thyroid Gland Papillary Carcinoma AJCC v8	C4683415	Differentiated Thyroid Gland Carcinoma 55 Years and Older AJCC v8 Stage	Stage I Differentiated Thyroid Gland Carcinoma AJCC v8	Stage IVC Differentiated Thyroid Gland Carcinoma AJCC v7	Stage I Differentiated Thyroid Gland Carcinoma Under 45 Years AJCC v7	Differentiated Thyroid Gland Carcinoma 55 Years and Older AJCC v8 Stage	3
C4683425::disease_is_stage	disease_is_stage	For which disease is {subj} a stage?	C4683425	Stage II Thyroid Gland Papillary Carcinoma Under 55 Years AJCC v8	C4683413	Differentiated Thyroid Gland Carcinoma Under 55 Years AJCC v8 Stage	Stage II Thyroid Gland Follicular Carcinoma Under 55 Years AJCC v8	Stage I Thyroid Gland Papillary Carcinoma Under 55 Years AJCC v8	Stage IVB Differentiated Thyroid Gland Carcinoma AJCC v8	Differentiated Thyroid Gland Carcinoma Under 55 Years AJCC v8 Stage	3
C4553875::disease_is_stage	disease_is_stage	For which disease is {subj} a stage?	C4553875	Stage IVB Differentiated Thyroid Gland Carcinoma AJCC v8	C4683415	Differentiated Thyroid Gland Carcinoma 55 Years and Older AJCC v8 Stage	Stage I Differentiated Thyroid Gland Carcinoma Under 55 Years AJCC v8	Stage II Thyroid Gland Follicular Carcinoma 55 Years and Older AJCC v8	Stage II Thyroid Gland Papillary Carcinoma 55 Years and Older AJCC v8	Differentiated Thyroid Gland Carcinoma 55 Years and Older AJCC v8 Stage	3
C1709312::disease_mapped_to_gene	disease_mapped_to_gene	Which gene is mapped to the disease {subj}?	C1709312	Oncocytic Variant Thyroid Gland Papillary Carcinoma	C1847162	GOLGA5/RET Fusion Gene	HMGA2/LHFP Fusion Gene	HMGA2/CCNB1IP1 Fusion Gene	TFG/NTRK1 Fusion Gene	GOLGA5/RET Fusion Gene	3
C1332471::disease_mapped_to_gene	disease_mapped_to_gene	Which gene is mapped to the disease {subj}?	C1332471	Benign Anal Granular Cell Tumor	C1412687	ATP6AP1 gene	NCKAP1 gene	ATP6AP1 gene	CPA6 gene	CPA1 gene	1
C5854746::disease_mapped_to_gene	disease_mapped_to_gene	Which gene is mapped to the disease {subj}?	C5854746	Childhood Acute Myeloid Leukemia with t(5;11)(q35;p15); NUP98-NSD1	C1847677	NSD1/NUP98 FUSION GENE	HOXD11/NUP98 FUSION GENE	NSD1/NUP98 FUSION GENE	MESDC2/SENP1 FUSION GENE	HOXA9/NUP98 FUSION GENE	1
C1336015::disease_may_have_abnormal_cell	disease_may_have_abnormal_cell	Which abnormal cell type may be found in the disease {subj}?	C1336015	Smoldering Adult T-Cell Leukemia/Lymphoma	C1514093	Neoplastic Small T-Lymphocyte	Neoplastic T-Cell Large Granular Lymphocyte	Neoplastic Small T-Prolymphocyte	Tumor Associated Lymphocyte	Neoplastic Small T-Lymphocyte	3
C5668167::disease_may_have_abnormal_cell	disease_may_have_abnormal_cell	Which abnormal cell type may be found in the disease {subj}?	C5668167	Pericardial Primary Effusion Lymphoma	C1513927	Neoplastic B-Immunoblast	Neoplastic Follicle Center B-Cell	Neoplastic Granulocyte	Neoplastic B-Immunoblast	Neoplastic Myeloid Cell	2
C0855142::disease_may_have_abnormal_cell	disease_may_have_abnormal_cell	Which abnormal cell type may be found in the disease {subj}?	C0855142	Nodal marginal zone B-cell lymphoma stage I	C1514058	Neoplastic Plasma Cell	Neoplastic Glial Cell	Neoplastic Melanocyte	Neoplastic Endocrine Cell	Neoplastic Plasma Cell	3
C0855184::disease_may_have_associated_disease	disease_may_have_associated_disease	Which other disease may be associated with the disease {subj}?	C0855184	Testicular choriocarcinoma stage III	C0010417	Cryptorchidism	Indeterminate sex and pseudohermaphroditism	Cryptorchidism	Opodidymus	Hologastroschisis	1
C5206775::disease_may_have_associated_disease	disease_may_have_associated_disease	Which other disease may be associated with the disease {subj}?	C5206775	Refractory Kidney Medullary Carcinoma	C0037054	Sickle Cell Trait	hemoglobinopathy trait SS	Sickle Cell Trait	Sickle cell arthropathy	Sickle cell beta plus thalassemia	1
C4725616::disease_may_have_associated_disease	disease_may_have_associated_disease	Which other disease may be associated with the disease {subj}?	C4725616	Refractory Ovarian Endometrioid Adenocarcinoma	C0476089	Endometrial Carcinoma	Type II Endometrial Adenocarcinoma	Recurrent Endometrial Undifferentiated Carcinoma	Recurrent Endometrial Endometrioid Adenocarcinoma	Endometrial Carcinoma	3
C1333842::disease_may_have_cytogenetic_abnormality	disease_may_have_cytogenetic_abnormality	Which cytogenetic abnormality may be present in the disease {subj}?	C1333842	Grade 3 Cutaneous Follicular Lymphoma	C1515604	del(6q23)	del(6p21)	del(6q23)	del(8p12p21)	del(11q22.3)	1
C4763841::disease_may_have_cytogenetic_abnormality	disease_may_have_cytogenetic_abnormality	Which cytogenetic abnormality may be present in the disease {subj}?	C4763841	Metastatic Bladder Giant Cell Urothelial Carcinoma	C1517979	Loss of Chromosome 2q	Loss of Chromosome 20	Chromosome 15q, partial deletion	Loss of Chromosome 2q	Chromosome 5q31-33 Deletion	2
C1332997::disease_may_have_cytogenetic_abnormality	disease_may_have_cytogenetic_abnormality	Which cytogenetic abnormality may be present in the disease {subj}?	C1332997	Childhood T Lymphoblastic Leukemia/Lymphoma	C1515789	t(7;9)(q34;q34.3)	t(3;3)(q21.3;q26.2)	t(7;9)(q34;q34.3)	t(13;22)(q22;q13.3)	t(1;19)(q23;p13.3)	1
C1334249::disease_may_have_finding	disease_may_have_finding	Which finding may be present in the disease {subj}?	C1334249	Intraductal Micropapillary Breast Carcinoma	C0520594	Breast Microcalcification	Breast Microcalcification	Cervical Microglandular Hyperplasia	Cortical calcifications	Calcified granuloma	0
C5237826::disease_may_have_finding	disease_may_have_finding	Which finding may be present in the disease {subj}?	C5237826	Advanced Colorectal Adenocarcinoma	C0024050	Lower gastrointestinal hemorrhage	Other neonatal gastrointestinal hemorrhage	Duodenal hemorrhage	Gastrointestinal bleeding neonatal	Lower gastrointestinal hemorrhage	3
C1519915::disease_may_have_finding	disease_may_have_finding	Which finding may be present in the disease {subj}?	C1519915	Vaginal Adenosquamous Carcinoma	C2979982	Vaginal Hemorrhage	Vaginal Hemorrhage	Hemorrhoidal Hemorrhage	Genital hemorrhage	Hemorrhage of tunica vaginalis	0
C1512749::disease_may_have_molecular_abnormality	disease_may_have_molecular_abnormality	Which molecular abnormality may be present in the disease {subj}?	C1512749	Invasive Bladder Urothelial Carcinoma with Trophoblastic Differentiation	C3266989	H-ras gene mutation	KRAS Exon 3 Mutation	Checkpoint kinase 2 gene mutation	NRAS Gene Amplification	H-ras gene mutation	3
C4743673::disease_may_have_molecular_abnormality	disease_may_have_molecular_abnormality	Which molecular abnormality may be present in the disease {subj}?	C4743673	Digestive System Small Cell Neuroendocrine Carcinoma	C1515171	TP53 Gene Inactivation	Deleterious TP53 Gene Mutation	Inactivating RAD51B Gene Mutation	TP53 Gene Inactivation	TGFBR2 Gene Inactivation	2
C1334052::disease_may_have_molecular_abnormality	disease_may_have_molecular_abnormality	Which molecular abnormality may be present in the disease {subj}?	C1334052	Human Papillomavirus-Related Cervical Squamous Cell Carcinoma	C1512127	HER2 gene amplification	HER2 gene amplification	TERT Deficiency	BLyS polymorphism	Hypermelanosis due to hormonal factor	0
C5401025::disposition_of	disposition_of	Which of the following is {subj} a disposition of?	C5401025	Estrogen receptor agonist (disposition)	C0059668	estrone sulfate	estrone sulfate	butacaine sulfate	estradiol valerate compounding powder	nomegestrol and estrogen	0
C5434066::disposition_of	disposition_of	Which of the following is {subj} a disposition of?	C5434066	Alpha-adrenergic and beta-adrenergic agonist (disposition)	C0304430	pseudoephedrine hydrochloride	pseudoephedrine hydrochloride	aminacrine hydrochloride	Methscopolamine nitrate + pseudoephedrine hydrochloride	cinnamedrine hydrochloride	0
C3853002::disposition_of	disposition_of	Which of the following is {subj} a disposition of?	C3853002	Androgen Synthesis Inhibitors	C5686001	Steroidal androgen synthesis inhibitor	testosterone cypionate compounding powder	Calcium antacid compound combinations	Steroidal androgen synthesis inhibitor	Testosterone esters	2
C0185622::do_not_code_with	do_not_code_with	Which of the following should not be coded with {subj}?	C0185622	Open treatment of fracture of orbit, except blowout; with implant	C1609555	Irrigation of implanted venous access device for drug delivery systems	Revision of implantable venous access port	Irrigation of implanted venous access device for drug delivery systems	Implantation of electronic stimulator into urinary bladder	Fluoroscopy guided removal of implantable venous access device	1
C0197419::do_not_code_with	do_not_code_with	Which of the following should not be coded with {subj}?	C0197419	Corneal wedge resection for correction of surgically induced astigmatism	C1609555	Irrigation of implanted venous access device for drug delivery systems	Irrigation of ventricular catheter	Accessing of implantable venous access port	Implantation of spinal drug delivery reservoir	Irrigation of implanted venous access device for drug delivery systems	3
C0812502::do_not_code_with	do_not_code_with	Which of the following should not be coded with {subj}?	C0812502	Laparoscopy, abdomen, peritoneum, and omentum, diagnostic, with or without collection of specimen(s) by brushing or washing (separate procedure)	C1736652	Laparoscopy, surgical, supracervical hysterectomy, for uterus 250 g or less	Total hysterectomy via vaginal approach using intrafascial technique	Laparoscopy, surgical, supracervical hysterectomy, for uterus 250 g or less	laparoscopic vaginal hysterectomy with repair of cystocele and rectocele	laparoscopy with fulguration of gynecologic lesions of uterine surface	1
C0695240::due_to	due_to	Which of the following is {subj} due to?	C0695240	Mechanical complication of gastrostomy	C0017196	Gastrostomy	Gastrostomy	Button gastrostomy feeding	Hepatogastrostomy	Gastroenterostomy	0
C4040068::due_to	due_to	Which of the following is {subj} due to?	C4040068	Hepatic coma due to acute hepatitis C	C0400914	Acute hepatitis C	Hepatitis with hepatic coma	Chronic viral hepatitis D	Acute hepatitis C	Acute hepatopathy	2
C0410706::due_to	due_to	Which of the following is {subj} due to?	C0410706	Osteoporotic kyphosis	C0029456	Osteoporosis	Low turnover osteopathy	Osteopenia or osteoporosis	Osteoporosis	Osteophyte	2
C3887685::enzyme_metabolizes_chemical_or_drug	enzyme_metabolizes_chemical_or_drug	Which chemical or drug is metabolized by the enzyme {subj}?	C3887685	Cytochrome P450 2D6, human	C0282321	propranolol hydrochloride	alprenolol hydrochloride	celiprolol hydrochloride	tulobuterol hydrochloride	propranolol hydrochloride	3
C0535996::enzyme_metabolizes_chemical_or_drug	enzyme_metabolizes_chemical_or_drug	Which chemical or drug is metabolized by the enzyme {subj}?	C0535996	CYP3A5 protein, human	C0006462	buspirone	profenamine	buspirone	Doprin	Buspirone only product	1
C1142644::enzyme_metabolizes_chemical_or_drug	enzyme_metabolizes_chemical_or_drug	Which chemical or drug is metabolized by the enzyme {subj}?	C1142644	cytochrome P450 3A4 protein, human	C0085170	astemizole	astemizole	terizidone	piminodine	tolazamide	0
C1517178::eo_disease_maps_to_human_disease	eo_disease_maps_to_human_disease	Which human disease does the experimental organism disease {subj} map to?	C1517178	Fibroma of the Mouse Skin	C0016045	fibroma	Recurrent fibromatosis	Fascial fibroma	fibroma	fetal myxolipoma	2
C1522089::eo_disease_maps_to_human_disease	eo_disease_maps_to_human_disease	Which human disease does the experimental organism disease {subj} map to?	C1522089	Adenoma of the Mouse Pulmonary System	C0001430	Adenoma	Carcinofibroma	Solid carcinoma	Adenoma	Flat adenoma	2
C1517177::eo_disease_maps_to_human_disease	eo_disease_maps_to_human_disease	Which human disease does the experimental organism disease {subj} map to?	C1517177	Fibroma of the Mouse Intestinal Tract	C0017185	Gastrointestinal Neoplasms	Gastrointestinal Neoplasms	Gastrointestinal Carcinoid Tumor	Jejunal Neoplasms	Gastrointestinal Stromal Tumors	0
C1826983::exhibited_by	exhibited_by	Which of the following exhibits {subj}?	C1826983	5-methyltetrahydrofolate-homocysteine methyltransferase reductase activity	C1453956	MTRR protein, human	MUSK protein, human	LTF protein, human	MTRR protein, human	TPR protein, human	2
C1149833::exhibited_by	exhibited_by	Which of the following exhibits {subj}?	C1149833	feruloyl esterase activity	C0117605	feruloyl esterase	2-ethylmalate synthase	vanillyl-alcohol oxidase	benzoyl-CoA reductase	feruloyl esterase	3
C1151783::exhibited_by	exhibited_by	Which of the following exhibits {subj}?	C1151783	methylenetetrahydrofolate reductase NADPH activity	C0066357	Methylenetetrahydrofolate reductase (NADPH)	Aldose-6-phosphate reductase (NADPH)	CoA-disulfide reductase (NADH)	Methylenetetrahydrofolate reductase (NADPH)	Protein-disulfide reductase (NAD(P)H)	2
C1439099::exhibits	exhibits	Which of the following is exhibited by {subj}?	C1439099	CHST15 protein, human	C1325240	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity	positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity	formate C-acetyltransferase activity	UDP-glucose:glycoprotein glucosyltransferase activity	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity	3
C1456416::exhibits	exhibits	Which of the following is exhibited by {subj}?	C1456416	MAPK13 protein, human	C1150590	SAP kinase 4 activity	SAP kinase 4 activity	protein kinase A signaling	negative regulation of protein kinase B signaling	protein kinase regulator activity	0
C2001855::exhibits	exhibits	Which of the following is exhibited by {subj}?	C2001855	EPHX1 protein, human	C2247484	cis-stilbene-oxide hydrolase activity	diacetyl reductase ((R)-acetoin forming) activity	cis-stilbene-oxide hydrolase activity	5'-hydroxyaverantin dehydrogenase activity	all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity	1
C0585526::finding_method_of	finding_method_of	Which of the following uses {subj} as a finding method?	C0585526	Exploration of colon	C2182884	descending colon procedure manual abdominal exploration noting liver nodules	Sigmoid colectomy and exteriorisation of bowel NEC	Left hemicolectomy and exteriorisation of bowel NEC	descending colon procedure manual abdominal exploration noting liver nodules	Emergency excision of abnormal appendix NEC	2
C1536105::finding_method_of	finding_method_of	Which of the following uses {subj} as a finding method?	C1536105	Computed Tomography Angiography	C3694981	CT angiography of head: aneurysm in right posterior communicating artery	CT angiography of head: aneurysm in right posterior communicating artery	angiography of cerebral portion of right carotid artery	fluoroscopic angiography of cerebral artery and left internal carotid artery	fluoroscopic angiography of cerebral artery with right carotid artery with IA contrast	0
C0412716::finding_method_of	finding_method_of	Which of the following uses {subj} as a finding method?	C0412716	Magnetic resonance imaging of ankle	C5765162	MRI of tibiocalcaneal ligament	MRI of calcaneus	MRI of acromioclavicular joint	MRI of tibiocalcaneal ligament	MRI of calcaneus, talus, navicular and cuboid bones of foot	2
C0032005::finding_site_of	finding_site_of	Which condition or procedure has {subj} as a finding site?	C0032005	Pituitary Gland	C5568640	Xanthomatous hypophysitis	Pseudomembranous stomatitis	Xanthomatous hypophysitis	Palmoplantar hypohidrosis	Secondary syphilitic osteopathy	1
C0000726::finding_site_of	finding_site_of	Which condition or procedure has {subj} as a finding site?	C0000726	Abdomen	C0206646	Fibromatosis, Abdominal	Fibromatosis, Abdominal	Intra-Abdominal Lymphangioma	Endometrioid adenofibroma, malignant	Cystadenoma, Papillary	0
C0700038::finding_site_of	finding_site_of	Which condition or procedure has {subj} as a finding site?	C0700038	Female Reproductive System	C0346170	Serous cystadenoma of ovary	Schneiderian carcinoma of cervix	Mucinous adenocarcinoma of appendix	Serous cystadenoma of ovary	Papillary serous cystadenoma	2
C1706514::gene_associated_with_disease	gene_associated_with_disease	Which disease is associated with the gene {subj}?	C1706514	GNAI2 wt Allele	C0032000	Pituitary Adenoma	Childhood Parathyroid Gland Adenoma	Pituitary Adenoma	Primary pituitary carcinoma	Pituitary Neoplasms	1
C2825749::gene_associated_with_disease	gene_associated_with_disease	Which disease is associated with the gene {subj}?	C2825749	MIRLET7G wt Allele	C0684249	Carcinoma of lung	Carcinoma of lung	Primary solid carcinoma of lung	Carcinoma of upper gum	Primary carcinoma of penis	0
C1416655::gene_associated_with_disease	gene_associated_with_disease	Which disease is associated with the gene {subj}?	C1416655	KIT gene	C0205851	Germ cell tumor	Extragonadal primary germ cell cancer	Germ cell tumor	Ovarian germ cell polyembryoma	Testicular gonadoblastoma	1
C1336804::gene_encodes_gene_product	gene_encodes_gene_product	Which gene product is encoded by the gene {subj}?	C1336804	Transforming Growth Factor-Beta Family Gene	C0053932	Bone Morphogenetic Proteins	Eosinophil Major Basic Protein	Bone Morphogenetic Proteins	MAGE-A1/MAGE-A3/NY-ESO-1 Peptides Vaccine	Heparan Sulfate Proteoglycans	1
C0017362::gene_encodes_gene_product	gene_encodes_gene_product	Which gene product is encoded by the gene {subj}?	C0017362	Genes, Regulator	C3254737	LRRTM2 protein, human	SEphB4-HSA	BCDX2 Complex	rca protein, plant	LRRTM2 protein, human	3
C1334166::gene_encodes_gene_product	gene_encodes_gene_product	Which gene product is encoded by the gene {subj}?	C1334166	Immunoprotein Gene	C1870106	Immunoglobulin Lambda-Like Polypeptide 1, human	Virus-specific Hyperimmune Globulins	Immune Globulin (Human)	Secretory Immunoglobulin A	Immunoglobulin Lambda-Like Polypeptide 1, human	3
C1709988::gene_in_chromosomal_location	gene_in_chromosomal_location	What is the chromosomal location of the gene {subj}?	C1709988	SMARCD2 wt Allele	C1520781	17q23-q24	14q23-q24.1	3q21-q28	17q23-q24	4q26-q32	2
C3538709::gene_in_chromosomal_location	gene_in_chromosomal_location	What is the chromosomal location of the gene {subj}?	C3538709	DDX3X wt Allele	C1520174	Xp11.3-p11.23	Xp11.3-p11.23	3p24.1-p22	1p36.2-p36.12	17p11.1	0
C1705990::gene_in_chromosomal_location	gene_in_chromosomal_location	What is the chromosomal location of the gene {subj}?	C1705990	LGALS8 wt Allele	C1521015	1q42-q43	13q12-q13	Xq11-q13	1q42-q43	1p32-q12	2
C1708291::gene_involved_in_molecular_abnormality	gene_involved_in_molecular_abnormality	In which molecular abnormality is the gene {subj} involved?	C1708291	CDC73 gene	C1708292	CDC73 Gene Mutation	CDC73 Gene Mutation	PCDH19 gene mutation	JAK Family Gene Mutation	Non-synonymous JAK Family Gene Mutation	0
C1335675::gene_involved_in_molecular_abnormality	gene_involved_in_molecular_abnormality	In which molecular abnormality is the gene {subj} involved?	C1335675	Receptor Tyrosine Kinase Gene	C5447807	ERBB2 NM_004448.3:c.2033G>A	CYP3A4 gene.c.6C>T	Point mutation in exon 21 (L858R)	ERBB2 NM_004448.3:c.2033G>A	NR5A1 gene mutation	2
C0919528::gene_involved_in_molecular_abnormality	gene_involved_in_molecular_abnormality	In which molecular abnormality is the gene {subj} involved?	C0919528	KMT2A gene	C1518132	KMT2A-MLLT1 Fusion Protein Expression	CDX2 Protein Overexpression	KMT2A-MLLT1 Fusion Protein Expression	EGFR gene overexpression	Non-synonymous RAS Family Gene Mutation	1
C1537502::gene_involved_in_pathogenesis_of_disease	gene_involved_in_pathogenesis_of_disease	In the pathogenesis of which disease is the gene {subj} involved?	C1537502	KRAS gene	C1335167	mucinous adenocarcinoma of ovary	mucinous adenocarcinoma of oral cavity	mucinous adenocarcinoma of ovary	mucinous adenocarcinoma of anal canal	mucinous adenocarcinoma of breast	1
C0079419::gene_involved_in_pathogenesis_of_disease	gene_involved_in_pathogenesis_of_disease	In the pathogenesis of which disease is the gene {subj} involved?	C0079419	TP53 gene	C1332166	Adenocarcinoma of the gastroesophageal junction	Primary carcinoma of lower third of esophagus	Adenocarcinoma of the gastroesophageal junction	Adenocarcinoma of duodenum	Basal cell carcinoma of esophagus	1

C2981613::disease_excludes_finding

disease_excludes_finding

Which finding is specifically excluded in the diagnosis of disease {subj}?

C2981613

Stage IIIA Digestive System Neuroendocrine Tumor AJCC v7

C0333868

Severe cytologic atypia

Neurofibrillary degeneration (morphologic abnormality)

Trisomy 18 (morphologic abnormality)

Severe cytologic atypia

Squamous metaplasia

2

C5420536::disease_excludes_finding

disease_excludes_finding

Which finding is specifically excluded in the diagnosis of disease {subj}?

C5420536

Advanced Cervical Adenosquamous Carcinoma

C0277565

Local disease

Regional enteritis

Basal pneumonia

Local disease

Nodal block

2

C4725707::disease_excludes_normal_cell_origin

disease_excludes_normal_cell_origin

Which normal cell origin is specifically excluded in the disease {subj}?

C4725707

Extracavitary Primary Effusion Lymphoma

C0032112

Plasma Cells

Phagocytes

Cells.HLA-B27

Plasma Cells

Plasma cells.abnormal marker pattern

2

C0079773::disease_excludes_normal_cell_origin

disease_excludes_normal_cell_origin

Which normal cell origin is specifically excluded in the disease {subj}?

C0079773

Lymphoma, T-Cell, Cutaneous

C0887899

Myeloid Cells

Myeloid precursor cell

Myeloid Cells

Pre-B Lymphocytes

Blood Cells

1

C5855556::disease_excludes_normal_cell_origin

disease_excludes_normal_cell_origin

Which normal cell origin is specifically excluded in the disease {subj}?

C5855556

IgM Monoclonal Gammopathy of Undetermined Significance, Plasma Cell Type

C1516097

B lymphoblast

Monocytoid B-Lymphocyte

CYIG+ lymphocyte

B lymphoblast

Activated B-Lymphocyte

2

C1335388::disease_excludes_normal_tissue_origin

disease_excludes_normal_tissue_origin

Which normal tissue origin is specifically excluded in the disease {subj}?

C1335388

Peripheral Intraneural Angiosarcoma

C0014609

Epithelium

Entire respiratory epithelium

Bile Duct Epithelium

Epidermis

Epithelium

3

C5554988::disease_excludes_normal_tissue_origin

disease_excludes_normal_tissue_origin

Which normal tissue origin is specifically excluded in the disease {subj}?

C5554988

Unresectable Myxofibrosarcoma

C0014609

Epithelium

Epidermis proper

Epidermal Ridge

Transitional epithelium

0

C0206717::disease_excludes_normal_tissue_origin

disease_excludes_normal_tissue_origin

Which normal tissue origin is specifically excluded in the disease {subj}?

C0206717

Olfactory Neuroblastoma

C1708239

Germinal Layer

Structure of germinal epithelium of ovary

Basal Domain of the Epithelium

Peyer Patch Germinal Center

Germinal Layer

3

C4520724::disease_excludes_primary_anatomic_site

disease_excludes_primary_anatomic_site

Which primary anatomic site is specifically excluded in the disease {subj}?

C4520724

Stage III Adult Soft Tissue Sarcoma AJCC v7

C0262950

Skeletal bone

Skeletal muscle structure of head

Skeleton of forearm

Skeletal bone

Bone structure of forearm

2

C1332903::disease_excludes_primary_anatomic_site

disease_excludes_primary_anatomic_site

Which primary anatomic site is specifically excluded in the disease {subj}?

C1332903

Cerebellar Vermis Medulloblastoma

C0037925

Spinal Cord

Spinal cord posterior horn

Spinal nerve root NEC

Spinal Cord

Spinal cord tissue structure

2

C1516417::disease_excludes_primary_anatomic_site

disease_excludes_primary_anatomic_site

Which primary anatomic site is specifically excluded in the disease {subj}?

C1516417

Cervical Large Cell Neuroendocrine Carcinoma

C0460004

Head and neck structure

External nose structure

Chest and abdominal vessels

Upper jaw region

Head and neck structure

3

C5206840::disease_has_abnormal_cell

disease_has_abnormal_cell

Which abnormal cell type is characteristic of the disease {subj}?

C5206840

Unresectable Oropharyngeal Squamous Cell Carcinoma

C1514101

Neoplastic Squamous Cell

Neoplastic Cell

Primitive neuroblastic cell

Lymphosarcoma cell

Neoplastic Squamous Cell

3

C2212014::disease_has_abnormal_cell

disease_has_abnormal_cell

Which abnormal cell type is characteristic of the disease {subj}?

C2212014

Ovarian Mucinous Adenocarcinofibroma

C0334227

Tumor cells, malignant

Entire endometrial glandular cell

Tumor cells, malignant

Vacuolated Malignant Fibroblast

Neoplastic Polygonal Cell

1

C2825773::disease_has_abnormal_cell

disease_has_abnormal_cell

Which abnormal cell type is characteristic of the disease {subj}?

C2825773

Malignant Epithelioid Cell Type Gastrointestinal Stromal Tumor

C1514104

Neoplastic Stromal Cell

Endocrine-Stromal Cell

Primitive neuroblastic cell

Neoplastic Epithelial Polygonal Cell

Neoplastic Stromal Cell

3

C2347926::disease_has_associated_anatomic_site

disease_has_associated_anatomic_site

Which anatomic site is associated with the disease {subj}?

C2347926

Refractory Spinal Cord Neoplasm

C0037925

Spinal Cord

Spinal nerve root S1

Spinal Cord

Spinal cord posterior horn

Cervical Spinal Nerve Root

1

C0033375::disease_has_associated_anatomic_site

disease_has_associated_anatomic_site

Which anatomic site is associated with the disease {subj}?

C0033375

Prolactinoma

C0149543

Base of skull structure

Orbital complex of bones - floor

Base of cochlear canal

Base of cochlear duct

0

C1520094::disease_has_associated_anatomic_site

disease_has_associated_anatomic_site

Which anatomic site is associated with the disease {subj}?

C1520094

Vulvar Sebaceous Carcinoma

C1261210

Reproductive system

Skeletal system

Arterial system

Digestive system subdivision

0

C0279748::disease_has_associated_disease

disease_has_associated_disease

Which other disease is associated with the disease {subj}?

C0279748

Undifferentiated carcinoma of nasopharynx

C0042769

Virus Diseases

B Virus Infection

Flavivirus Infections

Virus Diseases

Coronaviridae Infections

2

C1335509::disease_has_associated_disease

disease_has_associated_disease

Which other disease is associated with the disease {subj}?

C1335509

Prostate Kaposi Sarcoma

C0042769

Virus Diseases

B Virus Infection

Filoviridae Infections

Virus Diseases

Pestivirus Infections

2

C2986686::disease_has_associated_disease

disease_has_associated_disease

Which other disease is associated with the disease {subj}?

C2986686

Ann Arbor Stage IV AIDS-Related Lymphoma

C0009450

Communicable Diseases

Immune System Diseases

Opportunistic Infections

Communicable Diseases

Pneumonia in bacterial diseases classified elsewhere

2

C0302592::disease_has_associated_gene

disease_has_associated_gene

Which gene is associated with the disease {subj}?

C0302592

Cervix carcinoma

C2826017

MIR218-1 wt Allele

MIR373 wt Allele

MIR191 wt Allele

MIR135B wt Allele

0

C0279628::disease_has_associated_gene

disease_has_associated_gene

Which gene is associated with the disease {subj}?

C0279628

Adenocarcinoma Of Esophagus

C1332804

CTSB gene

LTB gene

CTSB gene

SPIB gene

CTNS gene

1

C0002395::disease_has_associated_gene

disease_has_associated_gene

Which gene is associated with the disease {subj}?

C0002395

Alzheimer's Disease

C1705380

ZFYVE9 wt Allele

WDFY2 wt Allele

SIGLEC9 wt Allele

ARHGEF10 wt Allele

ZFYVE9 wt Allele

3

C5238468::disease_has_finding

disease_has_finding

Which finding is characteristic of the disease {subj}?

C5238468

Locally Advanced Neuroendocrine Neoplasm

C0277565

Local disease

Disseminated scars

Burn shock

Local disease

Bone destruction

2

C4764032::disease_has_finding

disease_has_finding

Which finding is characteristic of the disease {subj}?

C4764032

Recurrent B-Cell Prolymphocytic Leukemia

C0277556

Recurrent disease

Recurrent phimosis

Recurrent disease

Recurrent infections, mild

Relapsing Fever

1

C1335035::disease_has_finding

disease_has_finding

Which finding is characteristic of the disease {subj}?

C1335035

Non-Destructive Post-Transplant Lymphoproliferative Disorder

C0021051

Immunologic Deficiency Syndromes

Hyper-IgM Immunodeficiency Syndrome, Type 1

Simian Acquired Immunodeficiency Syndrome

Immune System Diseases

0

C0677689::disease_has_molecular_abnormality

disease_has_molecular_abnormality

Which molecular abnormality is characteristic of the disease {subj}?

C0677689

Ann Arbor Stage II Grade 3 Contiguous Follicular Lymphoma

C1516672

Clonal Immunoglobulin Gene Rearrangement

Absence of Biallelic TCRgamma Deletion

Clonal Immunoglobulin Gene Rearrangement

FEV Gene Rearrangement

IGH Gene Rearrangement

1

C5670614::disease_has_molecular_abnormality

disease_has_molecular_abnormality

Which molecular abnormality is characteristic of the disease {subj}?

C5670614

Embryonal Tumor with Multilayered Rosettes, DICER1-Mutated

C4528702

DICER1 Gene Mutation

Deleterious DICER1 Gene Mutation

DICER1 Gene Mutation

DOT1L Gene Mutation

DIS3 Gene Mutation

1

C0281700::disease_has_molecular_abnormality

disease_has_molecular_abnormality

Which molecular abnormality is characteristic of the disease {subj}?

C0281700

Stage I Childhood Burkitt Lymphoma

C1516673

Clonal Immunoglobulin Heavy Chain Gene Rearrangement

Absence of Biallelic TCRgamma Deletion

IGK Gene Rearrangement

T-Cell Receptor Gene Rearrangement

Clonal Immunoglobulin Heavy Chain Gene Rearrangement

3

C5669728::disease_has_normal_cell_origin

disease_has_normal_cell_origin

From which normal cell type does the disease {subj} originate?

C5669728

Extramedullary Disease in Multiple Myeloma Involving the Skin

C1511241

Bone Marrow-Homing Plasma Cell

Mobilized Peripheral Blood Stem Cell

Neoplastic Medium-Sized Lymphocyte

Neoplastic Small to Medium-Sized B-Lymphocyte Resembling a Centrocyte

0

C4682696::disease_has_normal_cell_origin

disease_has_normal_cell_origin

From which normal cell type does the disease {subj} originate?

C4682696

Stage IIB Penile Cancer AJCC v8

C0014597

Epithelial Cells

Ciliated epithelial cell

Epithelial Cells

Endocrine Cells

Malignant Myoepithelial Cell

1

C5855486::disease_has_normal_cell_origin

disease_has_normal_cell_origin

From which normal cell type does the disease {subj} originate?

C5855486

B Acute Lymphoblastic Leukemia with HLF Rearrangement

C0024264

Lymphocyte

CD105+ lymphocyte

HLE+ lymphocyte

Lymphocyte

B-Lymphocytes, Regulatory

2

C3146256::disease_has_normal_tissue_origin

disease_has_normal_tissue_origin

From which normal tissue does the disease {subj} originate?

C3146256

Stage II Rectal Cancer AJCC v7

C0014609

Epithelium

Oral epithelium tissue specimen

Stratified squamous epithelium

Epidermal basement zone

Epithelium

3

C4727196::disease_has_normal_tissue_origin

disease_has_normal_tissue_origin

From which normal tissue does the disease {subj} originate?

C4727196

Recurrent Gastroesophageal Junction Adenocarcinoma

C0014609

Epithelium

Endothelium

Epidermal Ridge

Epithelium

Ductal Epithelium

2

C1292772::disease_has_normal_tissue_origin

disease_has_normal_tissue_origin

From which normal tissue does the disease {subj} originate?

C1292772

Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

C0229619

Hemopoietic tissue

All bone marrow of bone organ

Hemopoietic tissue

Entire transplanted bone marrow

Genitourinary lymphoid tissue

1

C4763829::disease_has_primary_anatomic_site

disease_has_primary_anatomic_site

What is the primary anatomic site of the disease {subj}?

C4763829

Metastatic Bladder Plasmacytoid Urothelial Carcinoma

C1508753

Urinary system

Skeletal system.peripheral

Articular system

Urinary system

Entire genitourinary system

2

C1710249::disease_has_primary_anatomic_site

disease_has_primary_anatomic_site

What is the primary anatomic site of the disease {subj}?

C1710249

Superficial Epithelioma with Sebaceous Differentiation

C0036505

Sebaceous Glands

Duct of sebaceous gland

Sebaceous Glands

Sebaceous lobule

Sebaceous gland of areola

1

C3899978::disease_has_primary_anatomic_site

disease_has_primary_anatomic_site

What is the primary anatomic site of the disease {subj}?

C3899978

BCLC Stage C Adult Hepatocellular Carcinoma

C0012240

Gastrointestinal system

Respiratory system subdivision

Upper digestive tract NEC

Gastrointestinal system

Entire digestive system

2

C4553846::disease_is_stage

disease_is_stage

For which disease is {subj} a stage?

C4553846

Stage IV Thyroid Gland Papillary Carcinoma AJCC v8

C4683415

Differentiated Thyroid Gland Carcinoma 55 Years and Older AJCC v8 Stage

Stage I Differentiated Thyroid Gland Carcinoma AJCC v8

Stage IVC Differentiated Thyroid Gland Carcinoma AJCC v7

Stage I Differentiated Thyroid Gland Carcinoma Under 45 Years AJCC v7

Differentiated Thyroid Gland Carcinoma 55 Years and Older AJCC v8 Stage

3

C4683425::disease_is_stage

disease_is_stage

For which disease is {subj} a stage?

C4683425

Stage II Thyroid Gland Papillary Carcinoma Under 55 Years AJCC v8

C4683413

Differentiated Thyroid Gland Carcinoma Under 55 Years AJCC v8 Stage

Stage II Thyroid Gland Follicular Carcinoma Under 55 Years AJCC v8

Stage I Thyroid Gland Papillary Carcinoma Under 55 Years AJCC v8

Stage IVB Differentiated Thyroid Gland Carcinoma AJCC v8

Differentiated Thyroid Gland Carcinoma Under 55 Years AJCC v8 Stage

3

C4553875::disease_is_stage

disease_is_stage

For which disease is {subj} a stage?

C4553875

Stage IVB Differentiated Thyroid Gland Carcinoma AJCC v8

C4683415

Differentiated Thyroid Gland Carcinoma 55 Years and Older AJCC v8 Stage

Stage I Differentiated Thyroid Gland Carcinoma Under 55 Years AJCC v8

Stage II Thyroid Gland Follicular Carcinoma 55 Years and Older AJCC v8

Stage II Thyroid Gland Papillary Carcinoma 55 Years and Older AJCC v8

Differentiated Thyroid Gland Carcinoma 55 Years and Older AJCC v8 Stage

3

C1709312::disease_mapped_to_gene

disease_mapped_to_gene

Which gene is mapped to the disease {subj}?

C1709312

Oncocytic Variant Thyroid Gland Papillary Carcinoma

C1847162

GOLGA5/RET Fusion Gene

HMGA2/LHFP Fusion Gene

HMGA2/CCNB1IP1 Fusion Gene

TFG/NTRK1 Fusion Gene

GOLGA5/RET Fusion Gene

3

C1332471::disease_mapped_to_gene

disease_mapped_to_gene

Which gene is mapped to the disease {subj}?

C1332471

Benign Anal Granular Cell Tumor

C1412687

ATP6AP1 gene

NCKAP1 gene

ATP6AP1 gene

CPA6 gene

CPA1 gene

1

C5854746::disease_mapped_to_gene

disease_mapped_to_gene

Which gene is mapped to the disease {subj}?

C5854746

Childhood Acute Myeloid Leukemia with t(5;11)(q35;p15); NUP98-NSD1

C1847677

NSD1/NUP98 FUSION GENE

HOXD11/NUP98 FUSION GENE

NSD1/NUP98 FUSION GENE

MESDC2/SENP1 FUSION GENE

HOXA9/NUP98 FUSION GENE

1

C1336015::disease_may_have_abnormal_cell

disease_may_have_abnormal_cell

Which abnormal cell type may be found in the disease {subj}?

C1336015

Smoldering Adult T-Cell Leukemia/Lymphoma

C1514093

Neoplastic Small T-Lymphocyte

Neoplastic T-Cell Large Granular Lymphocyte

Neoplastic Small T-Prolymphocyte

Tumor Associated Lymphocyte

Neoplastic Small T-Lymphocyte

3

C5668167::disease_may_have_abnormal_cell

disease_may_have_abnormal_cell

Which abnormal cell type may be found in the disease {subj}?

C5668167

Pericardial Primary Effusion Lymphoma

C1513927

Neoplastic B-Immunoblast

Neoplastic Follicle Center B-Cell

Neoplastic Granulocyte

Neoplastic B-Immunoblast

Neoplastic Myeloid Cell

2

C0855142::disease_may_have_abnormal_cell

disease_may_have_abnormal_cell

Which abnormal cell type may be found in the disease {subj}?

C0855142

Nodal marginal zone B-cell lymphoma stage I

C1514058

Neoplastic Plasma Cell

Neoplastic Glial Cell

Neoplastic Melanocyte

Neoplastic Endocrine Cell

Neoplastic Plasma Cell

3

C0855184::disease_may_have_associated_disease

disease_may_have_associated_disease

Which other disease may be associated with the disease {subj}?

C0855184

Testicular choriocarcinoma stage III

C0010417

Cryptorchidism

Indeterminate sex and pseudohermaphroditism

Cryptorchidism

Opodidymus

Hologastroschisis

1

C5206775::disease_may_have_associated_disease

disease_may_have_associated_disease

Which other disease may be associated with the disease {subj}?

C5206775

Refractory Kidney Medullary Carcinoma

C0037054

Sickle Cell Trait

hemoglobinopathy trait SS

Sickle Cell Trait

Sickle cell arthropathy

Sickle cell beta plus thalassemia

1

C4725616::disease_may_have_associated_disease

disease_may_have_associated_disease

Which other disease may be associated with the disease {subj}?

C4725616

Refractory Ovarian Endometrioid Adenocarcinoma

C0476089

Endometrial Carcinoma

Type II Endometrial Adenocarcinoma

Recurrent Endometrial Undifferentiated Carcinoma

Recurrent Endometrial Endometrioid Adenocarcinoma

Endometrial Carcinoma

3

C1333842::disease_may_have_cytogenetic_abnormality

disease_may_have_cytogenetic_abnormality

Which cytogenetic abnormality may be present in the disease {subj}?

C1333842

Grade 3 Cutaneous Follicular Lymphoma

C1515604

del(6q23)

del(6p21)

del(6q23)

del(8p12p21)

del(11q22.3)

1

C4763841::disease_may_have_cytogenetic_abnormality

disease_may_have_cytogenetic_abnormality

Which cytogenetic abnormality may be present in the disease {subj}?

C4763841

Metastatic Bladder Giant Cell Urothelial Carcinoma

C1517979

Loss of Chromosome 2q

Loss of Chromosome 20

Chromosome 15q, partial deletion

Loss of Chromosome 2q

Chromosome 5q31-33 Deletion

2

C1332997::disease_may_have_cytogenetic_abnormality

disease_may_have_cytogenetic_abnormality

Which cytogenetic abnormality may be present in the disease {subj}?

C1332997

Childhood T Lymphoblastic Leukemia/Lymphoma

C1515789

t(7;9)(q34;q34.3)

t(3;3)(q21.3;q26.2)

t(7;9)(q34;q34.3)

t(13;22)(q22;q13.3)

t(1;19)(q23;p13.3)

1

C1334249::disease_may_have_finding

disease_may_have_finding

Which finding may be present in the disease {subj}?

C1334249

Intraductal Micropapillary Breast Carcinoma

C0520594

Breast Microcalcification

Cervical Microglandular Hyperplasia

Cortical calcifications

Calcified granuloma

0

C5237826::disease_may_have_finding

disease_may_have_finding

Which finding may be present in the disease {subj}?

C5237826

Advanced Colorectal Adenocarcinoma

C0024050

Lower gastrointestinal hemorrhage

Other neonatal gastrointestinal hemorrhage

Duodenal hemorrhage

Gastrointestinal bleeding neonatal

Lower gastrointestinal hemorrhage

3

C1519915::disease_may_have_finding

disease_may_have_finding

Which finding may be present in the disease {subj}?

C1519915

Vaginal Adenosquamous Carcinoma

C2979982

Vaginal Hemorrhage

Hemorrhoidal Hemorrhage

Genital hemorrhage

Hemorrhage of tunica vaginalis

0

C1512749::disease_may_have_molecular_abnormality

disease_may_have_molecular_abnormality

Which molecular abnormality may be present in the disease {subj}?

C1512749

Invasive Bladder Urothelial Carcinoma with Trophoblastic Differentiation

C3266989

H-ras gene mutation

KRAS Exon 3 Mutation

Checkpoint kinase 2 gene mutation

NRAS Gene Amplification

H-ras gene mutation

3

C4743673::disease_may_have_molecular_abnormality

disease_may_have_molecular_abnormality

Which molecular abnormality may be present in the disease {subj}?

C4743673

Digestive System Small Cell Neuroendocrine Carcinoma

C1515171

TP53 Gene Inactivation

Deleterious TP53 Gene Mutation

Inactivating RAD51B Gene Mutation

TP53 Gene Inactivation

TGFBR2 Gene Inactivation

2

C1334052::disease_may_have_molecular_abnormality

disease_may_have_molecular_abnormality

Which molecular abnormality may be present in the disease {subj}?

C1334052

Human Papillomavirus-Related Cervical Squamous Cell Carcinoma

C1512127

HER2 gene amplification

TERT Deficiency

BLyS polymorphism

Hypermelanosis due to hormonal factor

0

C5401025::disposition_of

disposition_of

Which of the following is {subj} a disposition of?

C5401025

Estrogen receptor agonist (disposition)

C0059668

estrone sulfate

butacaine sulfate

estradiol valerate compounding powder

nomegestrol and estrogen

0

C5434066::disposition_of

disposition_of

Which of the following is {subj} a disposition of?

C5434066

Alpha-adrenergic and beta-adrenergic agonist (disposition)

C0304430

pseudoephedrine hydrochloride

aminacrine hydrochloride

Methscopolamine nitrate + pseudoephedrine hydrochloride

cinnamedrine hydrochloride

0

C3853002::disposition_of

disposition_of

Which of the following is {subj} a disposition of?

C3853002

Androgen Synthesis Inhibitors

C5686001

Steroidal androgen synthesis inhibitor

testosterone cypionate compounding powder

Calcium antacid compound combinations

Steroidal androgen synthesis inhibitor

Testosterone esters

2

C0185622::do_not_code_with

do_not_code_with

Which of the following should not be coded with {subj}?

C0185622

Open treatment of fracture of orbit, except blowout; with implant

C1609555

Irrigation of implanted venous access device for drug delivery systems

Revision of implantable venous access port

Irrigation of implanted venous access device for drug delivery systems

Implantation of electronic stimulator into urinary bladder

Fluoroscopy guided removal of implantable venous access device

1

C0197419::do_not_code_with

do_not_code_with

Which of the following should not be coded with {subj}?

C0197419

Corneal wedge resection for correction of surgically induced astigmatism

C1609555

Irrigation of implanted venous access device for drug delivery systems

Irrigation of ventricular catheter

Accessing of implantable venous access port

Implantation of spinal drug delivery reservoir

Irrigation of implanted venous access device for drug delivery systems

3

C0812502::do_not_code_with

do_not_code_with

Which of the following should not be coded with {subj}?

C0812502

Laparoscopy, abdomen, peritoneum, and omentum, diagnostic, with or without collection of specimen(s) by brushing or washing (separate procedure)

C1736652

Laparoscopy, surgical, supracervical hysterectomy, for uterus 250 g or less

Total hysterectomy via vaginal approach using intrafascial technique

Laparoscopy, surgical, supracervical hysterectomy, for uterus 250 g or less

laparoscopic vaginal hysterectomy with repair of cystocele and rectocele

laparoscopy with fulguration of gynecologic lesions of uterine surface

1

C0695240::due_to

due_to

Which of the following is {subj} due to?

C0695240

Mechanical complication of gastrostomy

C0017196

Gastrostomy

Button gastrostomy feeding

Hepatogastrostomy

Gastroenterostomy

0

C4040068::due_to

due_to

Which of the following is {subj} due to?

C4040068

Hepatic coma due to acute hepatitis C

C0400914

Acute hepatitis C

Hepatitis with hepatic coma

Chronic viral hepatitis D

Acute hepatitis C

Acute hepatopathy

2

C0410706::due_to

due_to

Which of the following is {subj} due to?

C0410706

Osteoporotic kyphosis

C0029456

Osteoporosis

Low turnover osteopathy

Osteopenia or osteoporosis

Osteoporosis

Osteophyte

2

C3887685::enzyme_metabolizes_chemical_or_drug

enzyme_metabolizes_chemical_or_drug

Which chemical or drug is metabolized by the enzyme {subj}?

C3887685

Cytochrome P450 2D6, human

C0282321

propranolol hydrochloride

alprenolol hydrochloride

celiprolol hydrochloride

tulobuterol hydrochloride

propranolol hydrochloride

3

C0535996::enzyme_metabolizes_chemical_or_drug

enzyme_metabolizes_chemical_or_drug

Which chemical or drug is metabolized by the enzyme {subj}?

C0535996

CYP3A5 protein, human

C0006462

buspirone

profenamine

buspirone

Doprin

Buspirone only product

1

C1142644::enzyme_metabolizes_chemical_or_drug

enzyme_metabolizes_chemical_or_drug

Which chemical or drug is metabolized by the enzyme {subj}?

C1142644

cytochrome P450 3A4 protein, human

C0085170

astemizole

terizidone

piminodine

tolazamide

0

C1517178::eo_disease_maps_to_human_disease

eo_disease_maps_to_human_disease

Which human disease does the experimental organism disease {subj} map to?

C1517178

Fibroma of the Mouse Skin

C0016045

fibroma

Recurrent fibromatosis

Fascial fibroma

fibroma

fetal myxolipoma

2

C1522089::eo_disease_maps_to_human_disease

eo_disease_maps_to_human_disease

Which human disease does the experimental organism disease {subj} map to?

C1522089

Adenoma of the Mouse Pulmonary System

C0001430

Adenoma

Carcinofibroma

Solid carcinoma

Adenoma

Flat adenoma

2

C1517177::eo_disease_maps_to_human_disease

eo_disease_maps_to_human_disease

Which human disease does the experimental organism disease {subj} map to?

C1517177

Fibroma of the Mouse Intestinal Tract

C0017185

Gastrointestinal Neoplasms

Gastrointestinal Carcinoid Tumor

Jejunal Neoplasms

Gastrointestinal Stromal Tumors

0

C1826983::exhibited_by

exhibited_by

Which of the following exhibits {subj}?

C1826983

5-methyltetrahydrofolate-homocysteine methyltransferase reductase activity

C1453956

MTRR protein, human

MUSK protein, human

LTF protein, human

MTRR protein, human

TPR protein, human

2

C1149833::exhibited_by

exhibited_by

Which of the following exhibits {subj}?

C1149833

feruloyl esterase activity

C0117605

feruloyl esterase

2-ethylmalate synthase

vanillyl-alcohol oxidase

benzoyl-CoA reductase

feruloyl esterase

3

C1151783::exhibited_by

exhibited_by

Which of the following exhibits {subj}?

C1151783

methylenetetrahydrofolate reductase NADPH activity

C0066357

Methylenetetrahydrofolate reductase (NADPH)

Aldose-6-phosphate reductase (NADPH)

CoA-disulfide reductase (NADH)

Methylenetetrahydrofolate reductase (NADPH)

Protein-disulfide reductase (NAD(P)H)

2

C1439099::exhibits

exhibits

Which of the following is exhibited by {subj}?

C1439099

CHST15 protein, human

C1325240

N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity

positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity

formate C-acetyltransferase activity

UDP-glucose:glycoprotein glucosyltransferase activity

N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity

3

C1456416::exhibits

exhibits

Which of the following is exhibited by {subj}?

C1456416

MAPK13 protein, human

C1150590

SAP kinase 4 activity

protein kinase A signaling

negative regulation of protein kinase B signaling

protein kinase regulator activity

0

C2001855::exhibits

exhibits

Which of the following is exhibited by {subj}?

C2001855

EPHX1 protein, human

C2247484

cis-stilbene-oxide hydrolase activity

diacetyl reductase ((R)-acetoin forming) activity

cis-stilbene-oxide hydrolase activity

5'-hydroxyaverantin dehydrogenase activity

all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity

1

C0585526::finding_method_of

finding_method_of

Which of the following uses {subj} as a finding method?

C0585526

Exploration of colon

C2182884

descending colon procedure manual abdominal exploration noting liver nodules

Sigmoid colectomy and exteriorisation of bowel NEC

Left hemicolectomy and exteriorisation of bowel NEC

descending colon procedure manual abdominal exploration noting liver nodules

Emergency excision of abnormal appendix NEC

2

C1536105::finding_method_of

finding_method_of

Which of the following uses {subj} as a finding method?

C1536105

Computed Tomography Angiography

C3694981

CT angiography of head: aneurysm in right posterior communicating artery

angiography of cerebral portion of right carotid artery

fluoroscopic angiography of cerebral artery and left internal carotid artery

fluoroscopic angiography of cerebral artery with right carotid artery with IA contrast

0

C0412716::finding_method_of

finding_method_of

Which of the following uses {subj} as a finding method?

C0412716

Magnetic resonance imaging of ankle

C5765162

MRI of tibiocalcaneal ligament

MRI of calcaneus

MRI of acromioclavicular joint

MRI of tibiocalcaneal ligament

MRI of calcaneus, talus, navicular and cuboid bones of foot

2

C0032005::finding_site_of

finding_site_of

Which condition or procedure has {subj} as a finding site?

C0032005

Pituitary Gland

C5568640

Xanthomatous hypophysitis

Pseudomembranous stomatitis

Xanthomatous hypophysitis

Palmoplantar hypohidrosis

Secondary syphilitic osteopathy

1

C0000726::finding_site_of

finding_site_of

Which condition or procedure has {subj} as a finding site?

C0000726

Abdomen

C0206646

Fibromatosis, Abdominal

Intra-Abdominal Lymphangioma

Endometrioid adenofibroma, malignant

Cystadenoma, Papillary

0

C0700038::finding_site_of

finding_site_of

Which condition or procedure has {subj} as a finding site?

C0700038

Female Reproductive System

C0346170

Serous cystadenoma of ovary

Schneiderian carcinoma of cervix

Mucinous adenocarcinoma of appendix

Serous cystadenoma of ovary

Papillary serous cystadenoma

2

C1706514::gene_associated_with_disease

gene_associated_with_disease

Which disease is associated with the gene {subj}?

C1706514

GNAI2 wt Allele

C0032000

Pituitary Adenoma

Childhood Parathyroid Gland Adenoma

Pituitary Adenoma

Primary pituitary carcinoma

Pituitary Neoplasms

1

C2825749::gene_associated_with_disease

gene_associated_with_disease

Which disease is associated with the gene {subj}?

C2825749

MIRLET7G wt Allele

C0684249

Carcinoma of lung

Primary solid carcinoma of lung

Carcinoma of upper gum

Primary carcinoma of penis

0

C1416655::gene_associated_with_disease

gene_associated_with_disease

Which disease is associated with the gene {subj}?

C1416655

KIT gene

C0205851

Germ cell tumor

Extragonadal primary germ cell cancer

Germ cell tumor

Ovarian germ cell polyembryoma

Testicular gonadoblastoma

1

C1336804::gene_encodes_gene_product

gene_encodes_gene_product

Which gene product is encoded by the gene {subj}?

C1336804

Transforming Growth Factor-Beta Family Gene

C0053932

Bone Morphogenetic Proteins

Eosinophil Major Basic Protein

Bone Morphogenetic Proteins

MAGE-A1/MAGE-A3/NY-ESO-1 Peptides Vaccine

Heparan Sulfate Proteoglycans

1

C0017362::gene_encodes_gene_product

gene_encodes_gene_product

Which gene product is encoded by the gene {subj}?

C0017362

Genes, Regulator

C3254737

LRRTM2 protein, human

SEphB4-HSA

BCDX2 Complex

rca protein, plant

LRRTM2 protein, human

3

C1334166::gene_encodes_gene_product

gene_encodes_gene_product

Which gene product is encoded by the gene {subj}?

C1334166

Immunoprotein Gene

C1870106

Immunoglobulin Lambda-Like Polypeptide 1, human

Virus-specific Hyperimmune Globulins

Immune Globulin (Human)

Secretory Immunoglobulin A

Immunoglobulin Lambda-Like Polypeptide 1, human

3

C1709988::gene_in_chromosomal_location

gene_in_chromosomal_location

What is the chromosomal location of the gene {subj}?

C1709988

SMARCD2 wt Allele

C1520781

17q23-q24

14q23-q24.1

3q21-q28

17q23-q24

4q26-q32

2

C3538709::gene_in_chromosomal_location

gene_in_chromosomal_location

What is the chromosomal location of the gene {subj}?

C3538709

DDX3X wt Allele

C1520174

Xp11.3-p11.23

3p24.1-p22

1p36.2-p36.12

17p11.1

0

C1705990::gene_in_chromosomal_location

gene_in_chromosomal_location

What is the chromosomal location of the gene {subj}?

C1705990

LGALS8 wt Allele

C1521015

1q42-q43

13q12-q13

Xq11-q13

1q42-q43

1p32-q12

2

C1708291::gene_involved_in_molecular_abnormality

gene_involved_in_molecular_abnormality

In which molecular abnormality is the gene {subj} involved?

C1708291

CDC73 gene

C1708292

CDC73 Gene Mutation

PCDH19 gene mutation

JAK Family Gene Mutation

Non-synonymous JAK Family Gene Mutation

0

C1335675::gene_involved_in_molecular_abnormality

gene_involved_in_molecular_abnormality

In which molecular abnormality is the gene {subj} involved?

C1335675

Receptor Tyrosine Kinase Gene

C5447807

ERBB2 NM_004448.3:c.2033G>A

CYP3A4 gene.c.6C>T

Point mutation in exon 21 (L858R)

ERBB2 NM_004448.3:c.2033G>A

NR5A1 gene mutation

2

C0919528::gene_involved_in_molecular_abnormality

gene_involved_in_molecular_abnormality

In which molecular abnormality is the gene {subj} involved?

C0919528

KMT2A gene

C1518132

KMT2A-MLLT1 Fusion Protein Expression

CDX2 Protein Overexpression

KMT2A-MLLT1 Fusion Protein Expression

EGFR gene overexpression

Non-synonymous RAS Family Gene Mutation

1

C1537502::gene_involved_in_pathogenesis_of_disease

gene_involved_in_pathogenesis_of_disease

In the pathogenesis of which disease is the gene {subj} involved?

C1537502

KRAS gene

C1335167

mucinous adenocarcinoma of ovary

mucinous adenocarcinoma of oral cavity

mucinous adenocarcinoma of ovary

mucinous adenocarcinoma of anal canal

mucinous adenocarcinoma of breast

1

C0079419::gene_involved_in_pathogenesis_of_disease

gene_involved_in_pathogenesis_of_disease

In the pathogenesis of which disease is the gene {subj} involved?

C0079419

TP53 gene

C1332166

Adenocarcinoma of the gastroesophageal junction

Primary carcinoma of lower third of esophagus

Adenocarcinoma of the gastroesophageal junction

Adenocarcinoma of duodenum

Basal cell carcinoma of esophagus

1