def translate_variant_reads(
        variant,
        variant_reads,
        protein_sequence_length,
        transcript_id_whitelist=None,
        min_alt_rna_reads=MIN_ALT_RNA_READS,
        min_variant_sequence_coverage=MIN_VARIANT_SEQUENCE_COVERAGE,
        min_transcript_prefix_length=MIN_TRANSCRIPT_PREFIX_LENGTH,
        max_transcript_mismatches=MAX_REFERENCE_TRANSCRIPT_MISMATCHES,
        include_mismatches_after_variant=INCLUDE_MISMATCHES_AFTER_VARIANT,
        variant_sequence_assembly=VARIANT_SEQUENCE_ASSEMBLY):
    """
    Given a variant and its associated alt reads, construct variant sequences
    and translate them into Translation objects.

    Returns 0 or more Translation objects.

    Parameters
    ----------
    variant : varcode.Variant

    variant_reads : sequence or generator
        AlleleRead objects supporting the variant

    protein_sequence_length : int
        Try to translate protein sequences of this length, though sometimes
        we'll have to return something shorter (depending on the RNAseq data,
        and presence of stop codons).

    transcript_id_whitelist : set, optional
        If given, expected to be a set of transcript IDs which we should use
        for determining the reading frame around a variant. If omitted, then
        try to use all overlapping reference transcripts.

    min_alt_rna_reads : int
        Drop variant sequences from loci with fewer than this number of
        RNA reads supporting the alt allele.

    min_variant_sequence_coverage : int
        Trim variant sequences to nucleotides covered by at least this many
        reads.

    min_transcript_prefix_length : int
        Minimum number of bases we need to try matching between the reference
        context and variant sequence.

    max_transcript_mismatches : int
        Don't try to determine the reading frame for a transcript if more
        than this number of bases differ.

    include_mismatches_after_variant : bool
        Include mismatches after the variant locus in the count compared
        against max_transcript_mismatches.

    variant_sequence_assembly : bool
        Use overlap assembly to construct longer variant cDNA sequences.
    """
    if len(variant_reads) == 0:
        logger.info("No supporting reads for variant %s", variant)
        return []

    # Adding an extra codon to the desired RNA sequence length in case we
    # need to clip nucleotides at the start/end of the sequence
    cdna_sequence_length = (protein_sequence_length + 1) * 3

    variant_sequences = reads_to_variant_sequences(
        variant=variant,
        reads=variant_reads,
        preferred_sequence_length=cdna_sequence_length,
        min_alt_rna_reads=min_alt_rna_reads,
        min_variant_sequence_coverage=min_variant_sequence_coverage,
        variant_sequence_assembly=variant_sequence_assembly)

    if not variant_sequences:
        logger.info("No spanning cDNA sequences for variant %s", variant)
        return []

    # try translating the variant sequences from the same set of
    # ReferenceContext objects, which requires using the longest
    # context_size to be compatible with all of the sequences. Some
    # sequences maybe have fewer nucleotides than this before the variant
    # and will thus have to be trimmed.
    context_size = max(
        len(variant_sequence.prefix)
        for variant_sequence in variant_sequences)

    reference_contexts = reference_contexts_for_variant(
        variant,
        context_size=context_size,
        transcript_id_whitelist=transcript_id_whitelist)

    return list(translation_generator(
        variant_sequences=variant_sequences,
        reference_contexts=reference_contexts,
        min_transcript_prefix_length=min_transcript_prefix_length,
        max_transcript_mismatches=max_transcript_mismatches,
        include_mismatches_after_variant=include_mismatches_after_variant,
        protein_sequence_length=protein_sequence_length))
Given a variant and its associated alt reads, construct variant sequences
    and translate them into Translation objects.

    Returns 0 or more Translation objects.

    Parameters
    ----------
    variant : varcode.Variant

    variant_reads : sequence or generator
        AlleleRead objects supporting the variant

    protein_sequence_length : int
        Try to translate protein sequences of this length, though sometimes
        we'll have to return something shorter (depending on the RNAseq data,
        and presence of stop codons).

    transcript_id_whitelist : set, optional
        If given, expected to be a set of transcript IDs which we should use
        for determining the reading frame around a variant. If omitted, then
        try to use all overlapping reference transcripts.

    min_alt_rna_reads : int
        Drop variant sequences from loci with fewer than this number of
        RNA reads supporting the alt allele.

    min_variant_sequence_coverage : int
        Trim variant sequences to nucleotides covered by at least this many
        reads.

    min_transcript_prefix_length : int
        Minimum number of bases we need to try matching between the reference
        context and variant sequence.

    max_transcript_mismatches : int
        Don't try to determine the reading frame for a transcript if more
        than this number of bases differ.

    include_mismatches_after_variant : bool
        Include mismatches after the variant locus in the count compared
        against max_transcript_mismatches.

    variant_sequence_assembly : bool
        Use overlap assembly to construct longer variant cDNA sequences.