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license: apache-2.0 |
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tags: |
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- flow-matching |
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- diffusion |
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- generative-ai |
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- biology |
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- chemistry |
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--- |
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## ⚡️ReQFlow: Rectified Quaternion Flow for Efficient and High-Quality Protein Backbone Generation |
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[](https://arxiv.org/abs/2502.14637)[](https://github.com/AngxiaoYue/ReQFlow)[](https://huggingface.co/AngxiaoYue/ReQFlow/tree/main) |
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Our **ReQFlow** achieves **state-of-the-art (SOTA)** performance 🎯 in protein backbone generation while requiring significantly fewer sampling steps and substantially reducing inference time. For example, it is **37×** faster than RFDiffusion and **62×** faster than Genie2 when generating a backbone of length 300, demonstrating both its effectiveness and efficiency 🚀🚀🔥. |
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<p align="center" style="margin-bottom: -2.8px;"> |
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<img src="assets/scheme_reqflow.png" width="95%"> |
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</p> |
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<p align="center" style="margin-top: 1.5px;"> |
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<img src="assets/prot_vis.png" width="95%"> |
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</p> |
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Ready to dive in? We’ve got checkpoints and step-by-step guides to get you inferencing in no time—playtime starts now! ✨ |
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## 🚀🚀🔥 |
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🔗arxiv link: [https://arxiv.org/abs/2502.14637](https://arxiv.org/abs/2502.14637) |
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🌳github link: [https://github.com/AngxiaoYue/ReQFlow](https://github.com/AngxiaoYue/ReQFlow) |