Our itineraries divide the city's heart into four from the Duomo north to Piazza San Marco; from the Piazza della Signoria, its Palazzo Vecchio and the Uffizi Galleries east to Piazza Santa Croce; from the Mercato Nuovo west to Piazza Santa Maria Novella; and the southern Left Bank of the Arno River around the Pitti Palace and the Piazzale Michelangelo.