The rainforest contains several species that can pose a hazard. Among the largest predatory creatures are the black caiman, jaguar, cougar, and anaconda. In the river, electric eels can produce an electric shock that can stun or kill, while piranha are known to bite and injure humans. Various species of poison dart frogs secrete lipophilic alkaloid toxins through their flesh. There are also numerous parasites and disease vectors. Vampire bats dwell in the rainforest and can spread the rabies virus. Malaria, yellow fever and Dengue fever can also be contracted in the Amazon region.