Matisse was also one of the first 20th-century artists to make color the central element of the painting, chosen to evoke emotions. "A certain blue penetrates your soul", he wrote. "A certain red affects your blood pressure." He also was familiar with the way that complementary colors, such as red and green, strengthened each other when they were placed next to each other. He wrote, "My choice of colors is not based on scientific theory; it is based on observation, upon feelings, upon the real nature of each experience ... I just try to find a color which corresponds to my feelings."