DNA samples from 1228 Russians show that the Y chromosomes analyzed, all except 20 (1.6%) fall into seven major haplogroups all characteristic to West Eurasian populations. Taken together, they account for 95% of the total Russian Y chromosomal pool. Only (0.7%) fell into haplogroups that are specific to East and South Asian populations. Mitochondrial DNA (mtDNA) examined in Poles and Russians revealed the presence of all major European haplogroups, which were characterized by similar patterns of distribution in Poles and Russians. An analysis of the DNA did not reveal any specific combinations of unique mtDNA haplotypes and their subclusters. The DNA clearly shows that both Poles and Russians are not different from the neighbouring European populations.