Institute of Psychiatry, London
Anatomy as a Basis for Clinical Medicine E C B Hall-Craggs pp 658 £27.50 ISBN 0-8067-0871-9 London: Pitman 1985 This is a straightforward, no-nonsense textbook of regional anatomy. It is well illustrated, lucidly written and sensibly laid out. The book is modern in its approach insofar as judicious reference is made to the clinical relevance of the anatomical structures and relationships described, though this is achieved without distorting the general flow ofthe text.
Institute of Psychiatry, London
Particular attention is paid to radiological anatomy including CAT scans, sonograms and magnetic resonance imaging. These are features which most textbooks of anatomy lack. Sections devoted to the functional aspects of anatomy and to surface anatomy are not as well illustrated or extensively described as those concerned with topographical anatomy. This is a pity as, indeed, is the omission of reference to developmental and comparative anatomy in parts of the text where they would greatly help the reader's understanding.
Institute of Psychiatry, London
The book is written for medical students and presents 'an appropriate amount of material' with this type of reader in mind. Anatomy teachers will be satisfied with the depth and extent of the coverage and with the author's refusal to cut corners. For the student this volume might, at first sight, appear to be a heavyweight, but this judgment would be unjust; the author has taken trouble to explain important topics properly and, in the long run, this saves time.
Institute of Psychiatry, London
The book does not cover the anatomy of the and sixth are of interest clinically for the immunologist or cancer physician. In the first chapter by Doherty, a history of the evolution of the immunosurveillance hypothesis is set out with a discussion of the data pertaining to the restriction of T-cell recognition, the nature of the MHC, the expression of MHC antigens on tumour cells and other germane topics in sections each with the writers own conclusions. The immunohistological analysis of human lymphoma by Stein et al. appraises the contribution of these techniques to dissecting human lymphoma pathology but unfortunately gives no reference to the studies that attempt to assess its value for disease -management. Richard Rifkind has written a concise chapter on murine erythroleukaemia as a model for inducer-mediated differentiation. Differentiation is related to transcription events at the globin locus on the genome. The fourth chapter by Robert Cardiff is an exposition on murine mammary hyperplasia as a precursor of murine mammary neoplasia and as a model for human breast hyperplasia and neoplasia. The incorporation of the MUMTV provirus at a critical site induces a protoneoplastic (hyperplastic) population that evolves to become fully malignant probably after further exposure to carcinogens. In Chapter 5 Fritz Anders et al. examine in detail the ornamental fish X. maculatus and X. helleri as models for inherited melanoma, with emphasis upon the importance of genes that regulate the transforming gene. Finally, Gershon parallels the control of immune function by T-cells as analogous to other biological systems which require fine tuning, notably the motoneurone system. Suppressor/ contrasuppressor T-cells not only explain the mechanisms of dictating the amplitude but also the quality of immune responses including those mediated by B-cells. In all the book makes very few concessions to the non-expert reader but each chapter is in itself a valuable 'state of the art' review of the field in which the authors are pre-eminent. The contents ofthese impressive reviews on catecholamines describe the plenary, symposium talks and selected voluntary papers presented at the 5th Catecholamine Symposium, Goteborg, Sweden, 1983. Part A covers the biochemical and physiological aspects of the storage, release, metabolism and uptake of catecholamines. Protein phosphorylation is clearly seen as an important mechanism which regulates tyrosine hydroxylase activity and neuronal function. Catecholamine receptors are extensively reviewed, including the solubilization and characterization of dopamine D2 receptors; and beta-and alpha-adrenergic receptors. Also included are the importance of catecholamines and their receptors in perinatal medicine; congestive heart failure, hypertension and ischaenia. One of the fundamental impressions of this volume is the explosion of different techniques used to studycatecholamine enzymes and receptors, which now include biochemical, immunochemical and molecular biology approaches. The chapters are well organized and provide excellent peer reviews of the topics covered.
Institute of Psychiatry, London
The title of Part B, 'Neuropharmacology and Central Nervrous System -Theoretical Aspects', is somewhat of a misnoma. Far from being theoretical, most chapters are informatively packed with experimental data and well constructed interpretation.
Institute of Psychiatry, London
This volume describes the mechanisms and modulation rather than characterization ofcentral catecholaminergic processes. (Another two volumes emerged from the 1983 symposium.) It is written primarily for the guidance of 'health professionals' concerned with the management of obesity, rather than for the obese man or woman in the street. It is now widely accepted that increasing energy expenditure. together with a decreased energy intake forms a sounder basis for weight loss than either regimen alone, and this book is, essentially, a practical manual written by specialists in nutrition, physical education, rehabilitation and behavioural therapy covering all these aspects of weight loss with particular reference to obese subjects. The importance of training, exercise testing, risk appraisal, evaluation of cardiovascular and respiratory function and the precautions necessary for the obese are discussed in relation to a wide range of different exercise programmes and to the guidelines of the American College of Sports Medicine and the American Heart Association Committee on Exercise. It is a useful guide for all those who are engaged in the management of obese patients. T G TAYLOR The contributors were asked to write 'positional papers' concerning their topic, and to express their views and opinions in an editorial fashion. To stimulate discussion, speakers had been invited with differing opinions, and every effort was made to stimulate discussion on controversial subjects. Extra papers have been added to give more complete coverage in the book, and edited transcripts of the discussions included. Sections on acquired immune deficiency syndrome (AIDS) and Legionnaire's disease are included, as well as infections in patients with neoplastic disease. The editors are to be congratulated on putting together an excellent review ofthe symposium which, judgingby the discussions, was highly successful. The majority of the contributions are well-written and authoritative. The edited discussions complement the papers and form a very informative part of the book. The subject is an evolving one, and many of the views strongly held in the 1970s are changing on a whole range of subjects from granulocyte transfusions to the use of isolation facilities. The chapter contributed by Dr Philip Pizzo and associates from the National Cancer Institute in the USA on the antibacterial management of cancer patients is strongly recommended to the busy physician unable to find time to read the whole book.
Institute of Psychiatry, London
This volume will be of interest to a much wider readership than the title suggests, and can be recommended to all physicians with an interest in the management of serious infections. J HOWARD SCARFE Since it is now impossible to read more than a fraction of the literature of any specialty, the regular review volume is an important event in the year; of those available in infectious diseases, 'Remington and Swartz' takes pride of place for the thoroughness, scholarship and balance with which its subjects are treated. The editors have chosen an interesting mixture of topics, some quite specialized ones of immediate current interest, others more general 'state of the art' reviews. This volume, somewhat smaller than its four predecessors, has essays on the following subjects: prostatitis syndromes; Staphylococcus epidermidis infections; management of nocardia infection; toxic shock syndrome; isolation of dangerous contagious diseases; nutrition and infection; dialysis infections; EBV and lymphoproliferative disorders; staphylococcal teichoic acid antibodies; granulocyte transfusion therapy; infections with intrauterine devices; hospital epidemiology; viridans streptococci; prophylaxis of Hinfluenzae infections; and current concepts of rheumatic fever. This series of volumes expounds clearly the many important current advances in the aetiology, pathogenesis and management of infections and reminds us how important both community-acquired and hospital-acquired infections are as a cause of morbidity and mortality even in modern society.
Institute of Psychiatry, London
The seeker after good up-to-date reviews on infectious disease will find this series invaluable. I read each volume with great enjoyment and profit, and go back to the previous volumes again and again. Keep going Remington and Swartz.
H P LAMB3ERT
Communicable Diseases Unit St George's Hospital, London

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