Not to be confused with Orange, California or Orange County, California. The Orange Cove Santa Fe Railway Depot now serves as City Hall and is also listed on the National Register of Historic Places. City of Orange Cove. Orange Cove is a small city in Fresno County, California, United States. The population was 9,078 at the 2010 census, up from 7,722 at the 2000 census. Almost all of Orange Cove's residents are Hispanic, many of whom are farmers.