Bactroban Cream (mupirocin calcium cream) is an antibiotic used to treat infections of the skin such as impetigo. Some formulations of Bactroban are available in generic form.Common side effects of Bactroban Cream include burning, stinging, itching or pain at first as your body adjusts to it.ur Bactroban Cream (mupirocin calcium cream) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. This is not a complete list of side effects and others may occur.