Define e-beam sterilization. e-beam sterilization synonyms, e-beam sterilization pronunciation, e-beam sterilization translation, English dictionary definition of e-beam sterilization. tr.v. sterÂ·ilÂ·ized , sterÂ·ilÂ·izÂ·ing , sterÂ·ilÂ·izÂ·es 1. To make free from live bacteria or other microorganisms. 2. To eliminate the ability of a person or...