Making the world better, one answer at a time. 21 vaccines before the age of six, and generally 6 more before the age of 18, for a total of 27 in childhood. Some vaccines are given multiple times (for example, the DTaP - diptheria, tetanus, and pertussis - is given 5 times). 21 vaccines before the age of six, and generally 6 more before the age of 18, for a total of 27 in childhood.