Inherited hemophilia. In 70% of cases of hemophilia, there is a known family history. The gene that causes hemophilia is passed from mother to child. A mother that carries the gene is called a carrier. A carrier has a 50% chance of having a son with hemophilia and a 50% chance of having a daughter who is also a carrier.In other words, a female carrier has a 25% chance of having a child with hemophilia. female can have Hemophilia because of X-inactivation or Lyonization. It is possible for one X to âshut-downâ or not to express itself. If the X chromosome with the Hemophilia gene is the active chromosome than she will have lower levels. 50% of carriers have low factor levels.