RESULTS	After four weeks of double-blind treatment , there was a statistically significant and clinically relevant improvement in the mean ( SD ) Asthma Control Questionnaire score in the ICS-treated group ( n = 6 ) ( decrease of 1.0 0.5 ) compared with the placebo group ( n = 6 ) ( decrease of 0.09 0.4 ) ( P = 0.008 ) .\