RESULTS	The effects of 0.5 mg of lasofoxifene on total breast cancer were similar regardless of Gail score , whereas the effects were markedly stronger for women with baseline estradiol levels greater than the median ( odds ratio = 0.11 ; 95 % CI = 0.02 to 0.51 ) vs those with levels less than the median ( odds ratio = 0.78 ; 95 % CI = 0.16 to 3.79 ; P ( interaction ) = .04 ) .\