RESULTS	All three non-switched groups maintained reductions in glycosylated haemoglobin ( HbA1c ; meanstandard deviation reductions across the 1.5-year period : linagliptin 2.5 plus metformin 1000 bid , -1.631.05 % ; linagliptin 2.5 plus metformin 500 bid , -1.321.06 % ; metformin 1000 bid , -1.250.91 % ) while the switched groups showed additional HbA1c reductions .\