RESULTS	The mean ( SD ) percentage changes from baseline of sex hormone-binding globulin , total T , and free T with oral CEE were +132.1 % ( 74.5 % ) , +16.4 % ( 43.8 % ) , and -32.7 % ( 25.9 % ) , respectively , versus +12.0 % ( 25.1 % ) , +1.2 % ( 43.7 % ) , and +1.0 % ( 45.0 % ) with TD E2 .\