RESULTS	With increasing proportions of soluble IAsp , the insulin formulations showed significantly higher early metabolic activity ( ratio of AUC ( GIR ) 0-6 h : BIAsp 50/BIAsp 30 = 1.28 [ P < 0.001 ] , BIAsp 70/BIAsp 50 = 1.18 [ P < 0.001 ) , IAsp/BIAsp 70 = 1.15 [ P < 0.01 ] ) and lower late metabolic activity ( ratio of AUC ( GIR ) 12-28 h : BIAsp 50/BIAsp 30 = 0.17 [ P < 0.01 ] , BIAsp 70/BIAsp 50 = 0.21 [ P < 0.05 ] ) .\