RESULTS	The mean serum HBV-DNA decreases from baseline at 3 , 6 , 12 , and 24 months were -3.23 , -4.41 , -5.32 , and -5.58 log ( 10 ) IU/mL in the ADV + ETV combination therapy groups , respectively ; the most significant among the three treatment groups ( p < 0.01 ) .\