METHODS	The following parameters were measured : symptom score , forced expiratory volume in 1 second ( FEV1 ) , provocative concentration of histamine causing a 20 % fall in FEV1 ( PC20 ) for histamine and peripheral blood eosinophil count , serum levels of eosinophil cationic protein ( ECP ) , soluble receptor of interleukin-2 ( sIL-2R ) , level of interleukin-4 ( IL-4 ) , level of soluble intercellular adhesion molecule-1 ( ICAM-1 ) , and immunoglobulin E ( IgE ) level before and after treatment .\