RESULTS	At three years , the mean ( + / - SE ) differences in bone mineral density between the women receiving 10 mg of alendronate daily and those receiving placebo were 8.8 + / - 0.4 percent in the spine , 5.9 + / - 0.5 percent in the femoral neck , 7.8 + / - 0.6 percent in the trochanter , and 2.5 + / - 0.3 percent in the total body ( P < 0.001 for all comparisons ) .\