RESULTS	The 12-week incidence of any grade HFSR was significantly lower in the UBC group versus the BSC-alone group ( 56.0 % v 73.6 % , respectively ; odds ratio [ OR ] , 0.457 ; 95 % CI , 0.344 to 0.608 ; P < .001 ) , as was the incidence of grade 2 HFSR ( 20.7 % v 29.2 % , respectively ; OR , 0.635 ; 95 % CI , 0.466 to 0.866 ; P = .004 ) .\