METHODS	Seventy-five adult male Sprague Dawley rats were randomized into five groups : ( 1 ) SBI + drug vehicle ( peanut oil , 1ml kg ( -1 ) ) ; ( 2 ) SBI + DEXA ( 1mg kg ( -1 ) ) ; ( 3 ) SBI + low-dose PRO ( 10mg kg ( -1 ) ) ; ( 4 ) SBI + high-dose PRO ( 20mg kg ( -1 ) ) ; and ( 5 ) sham SBI + drug vehicle .\