RESULTS	In the total hip BMD , there was no difference in the response to estradiol in smokers vs. non-smokers ( 1.4 % vs. 1.4 % , p = 0.89 ) , whereas the change in the hip on the placebo was similar to that seen in the spine ( -3.7 % vs. -2.6 % , p = 0.08 ) .\