RESULTS	The rate of cure of the index lesion was 81 % ( 95 % confidence interval [ CI ] , 73 to 87 ) for paromomycin-gentamicin , 82 % ( 95 % CI , 74 to 87 ) for paromomycin alone , and 58 % ( 95 % CI , 50 to 67 ) for vehicle control ( P < 0.001 for each treatment group vs. the vehicle-control group ) .\