METHODS	This 1-year randomised , double-blind study was an extension of a 6-month randomised controlled trial , in which adults with type 2 diabetes received one of six treatment regimens ( linagliptin 2.5 mg plus metformin 500mg bid , linagliptin 2.5 mg plus metformin mg 1000 bid , metformin 1000mg bid , metformin 500mg bid , linagliptin 5mg qd or placebo ) .\