RESULTS	Saxagliptin plus metformin provided significant adjusted mean decreases versus placebo plus metformin ( p 0.0052 ) in HbA ( 1c ) ( -0.78 % versus -0.37 % ) , fasting plasma glucose ( -1.14 mmol/L versus -0.58 mmol/L ) , and postprandial glucose area under the curve from 0 to 180 min ( -315 mmol min/L versus -160 mmol min/L ) .\