RESULTS	The mean ( SD ) percentage changes of cortisol-binding globulin , total C , and free C with oral CEE were +18.0 % ( 19.5 % ) , +29.2 % ( 46.3 % ) , and +50.4 % ( 126.5 % ) , respectively , versus -2.2 % ( 11.3 % ) , -6.7 % ( 30.8 % ) , and +1.8 % ( 77.1 % ) with TD E2 .\