METHODS	They were assigned in a 2:1 ratio with a validated interactive voice and internet response system to either 28 day cycles of pomalidomide ( 4 mg/day on days 1-21 , orally ) plus low-dose dexamethasone ( 40 mg/day on days 1 , 8 , 15 , and 22 , orally ) or high-dose dexamethasone ( 40 mg/day on days 1-4 , 9-12 , and 17-20 , orally ) until disease progression or unacceptable toxicity .\