RESULTS	During trimetazidine therapy , patients had significant improvement on angina functional class ( P < .05 ) , with decrease in the number of weekly angina episodes ( 1.5 + / - 0.8 vs 0.4 + / - 0.7 , P < .01 ) , and in sublingual nitrate doses ( 1.4 + / - 0.7 mg vs 0.1 + / - 0.3 mg , P < .001 ) .\