RESULTS	Both short - and long-term treatments with iloprost significantly reduced PAI-1 activity ( baseline vs end : 17.4 + / - 1.9 AU/ml vs 15.0 + / - 1.6 AU/ml , P < 0.02 ; 20.5 + / - 7.6 AU/ml vs 7.9 + / - 2.1 AU/ml , P < 0.002 , respectively ) .\