RESULTS	For PERMP-A , postdose LS mean ( SE ) effect sizes were 0.5 ( 0.15 ) , 0.8 ( 0.16 ) , 0.7 ( 0.16 ) , 0.7 ( 0.16 ) , 0.7 ( 0.16 ) , and 0.6 ( 0.16 ) at 2 , 4 , 8 , 10 , 12 , and 14 hours , respectively .\