RESULTS	Mean 6-month serum creatinine ( primary safety variable ) was 112 + / -31 micromol/L ( 1.26 + / -0.35 mg/dL ) and 127 + / -50 micromol/L ( 1.44 + / -0.57 mg/dL ) in the low and standard tacrolimus groups , respectively , ( n.s. ) ; mean estimated GFR ( Nankivell ) was 75.3 + / -16.6 mL/min and 72.5 + / -15.2 mL/min ( n.s. ) .\