METHODS	Patients were randomized to receive either an omeprazole treatment strategy ( 363 ) consisting of omeprazole 10 mg stepping up to 20 mg and 40 mg as required , or an antacid-alginate/ranitidine treatment strategy ( 362 ) consisting of antacid-alginate 10 mL q.d.s. stepping up to ranitidine 150 mg b.d. and 150 mg q.d.s. as required .\