RESULTS	By 12 weeks , ERr 731 caused a highly significant reduction of the MRS total score from 27.0 + / - 4.7 points to 12.4 + / - 5.3 points when compared to the placebo-induced decrease from 27.0 + / - 5.3 points to 24.0 + / - 6.2 points ( P < .0001 ) .\