METHODS	Noninclusion criteria were histologically proven tracheobronchial involvement , esotracheal fistula , major alteration of general health status ( Karnofsky score < 50 ) , cerebral or extensive ( > 30 % of parenchyma ) hepatic metastasis , peritoneal carcinomatosis , associated or previously treated upper airway cancer , or , conversely , complete resection of tumor without lymph node involvement .\