METHODS	We assessed the previously published gene expression modules describing biological processes [ proliferation , apoptosis , human epidermal receptor 2 ( HER2 ) and estrogen ( ER ) signaling , tumor invasion , immune response , and angiogenesis ] and pathways ( Ras , MAPK , PTEN , AKT-MTOR , PI3KCA , IGF1 , Src , Myc , E2F3 , and - catenin ) and the intrinsic subtypes ( PAM50 ) .\