RESULTS	Mean A1C was reduced by 1.1 % with metformin/colesevelam ( from 7.8 % at baseline to 6.6 % at study end ) and by 0.8 % with metformin/placebo ( from 7.5 % to 6.7 % ) , resulting in a treatment difference of -0.3 % at study end ( P = .0035 ) .\