RESULTS	For the 1.01-microm aerosol , I :O ratios averaged 2.09 + / -0.96 and 3.19 + / -1.95 ( p < 0.05 ) , indicating that deposition was predominantly in the smaller airways while breathing at 18 + / -5 L/min and in the larger airways while breathing at 38 + / -8 L/min , respectively .\