RESULTS	Total homocysteine concentrations decreased significantly ( P < 0.001 ) in women ( n = 50 ) who took 250 microgram folic acid/d [ mean ( + / - SEM ) deviation from baseline : - 11.4 + / - 198 % ] and in women ( n = 45 ) who took 500 microgram folic acid/d ( -21.8 + 1.49 % ) .\