RESULTS	Finasteride significantly decreased the overall risk of high grade prostatic intraepithelial neoplasia ( alone and with cancer ) from 570 cases ( 11.7 % ) in the placebo group to 420 ( 9.2 % ) in the finasteride group ( HR 0.79 , 95 % CI 0.70-0 .89 , p < 0.001 ) .\