RESULTS	After adjustment , nonpersistence was associated with the composite end point of cardiovascular death , myocardial infarction , stroke , or hospitalization for heart failure ( hazard ratio 1.24 , 99 % CI 1.09-1 .40 , P < .0001 ) , cardiovascular death alone ( 1.87 , 1.60-2 .19 , P < .0001 ) , and heart failure hospitalization alone ( 1.32 , 1.04-1 .67 , P = .0023 ) .\