RESULTS	After 12 weeks , using intent-to-treat analysis with last observation carried forward , there were no significant differences between laser-treated and untreated skin for changes in mean papule counts ( -4.2 vs -2.2 ; P = .08 ) , mean pustule counts ( 0 vs -1.0 ; P = .12 ) , or mean comedone counts ( 2.9 vs 1.6 ; P = .63 ) .\