METHODS	A total of 104 postmenopausal women aged 50-75 years with osteoporosis were allocated randomly to three groups : ( 1 ) conjugated oestrogen plus medroxyprogesterone acetate ( HRT-MPA , with significant glucocorticoid activity ) ; ( 2 ) conjugated oestrogen plus norethisterone ( HRT-NET , with no significant glucocorticoid activity ) ; and ( 3 ) control ( no treatment ) .\