METHODS	One-hundred patients undergoing chemotherapy were randomized to treatment with G-CSF at 5 Kg/kg for established febrile neutropenia ( ANC < 1000/microl ) ( Group A ) or G-CSF at 263 Kg/day if ANC was 1500/microl or less on the day of the expected nadir , with the duration of treatment determined by the severity of neutropenia ( Group B ) .\