METHODS	Nine randomly selected patients underwent intratumoral injection of OK-432 mixed with fibrinogen , which was performed on the third preoperative day ( OK-432 and fibrinogen plus 5 ' - deoxy-5-fluorouridine group ) ; eleven patients were given oral 5 ' - deoxy-5-fluorouridine only ( 5 ` deoxy-5-fluorouridine group ) .\