RESULTS	Patients with HNF-1alpha diabetes had a 5.2-fold greater response to gliclazide than to metformin ( fasting plasma glucose reduction 4.7 vs 0.9 mmol/L , p = 0.0007 ) and 3.9-fold greater response to gliclazide than those with type 2 diabetes ( p = 0.002 ) .\