RESULTS	Atenolol significantly worsened GIM parameters , fasting glucose levels ( 5.3 + / -0.9 to 6.0 + / -1.5 mmol/L ; P : = 0.003 ) , fasting insulin levels ( 121 + / -121 to 189 + / -228 pmol/L ; P : = 0.03 ) , and most other relevant metabolic measures ( P : < 0.05 for all ) .\