OBJECTIVE	The purpose of this study is twofold : ( 1 ) to determine factors affecting cord blood IgE level and ( 2 ) to determine whether cord blood IgE predicts the development of asthma and other IgE-mediated allergic diseases in high risk ( defined as those with at least one first degree relative with asthma or 2 first degree relatives with other IgE-mediated allergic diseases ) infants at 12 months .\