RESULTS	Conivaptan at each dosage increased urine output significantly more than placebo at 24 hours ( P < or = .02 ) , with the difference averaging 1.0 to 1.5 L. Decreases in mean body weight with conivaptan 40 and 80 mg/d ( approximately 1-2 kg ) paralleled the increases in urine output but did not reach statistical significance .\