CREATE TABLE medicine_enzyme_interaction (enzyme_id DECIMAL, medicine_id DECIMAL, interaction_type TEXT)
CREATE TABLE medicine (id DECIMAL, name TEXT, trade_name TEXT, fda_approved TEXT)
CREATE TABLE enzyme (id DECIMAL, name TEXT, location TEXT, product TEXT, chromosome TEXT, omim DECIMAL, porphyria TEXT)

How many medicines have the FDA approval status 'No' ?
SELECT COUNT(*) FROM medicine WHERE fda_approved = 'No'
SELECT COUNT(*) FROM "medicine" WHERE "fda_approved" = 'No'