CREATE TABLE table_5603 ("District" TEXT, "Incumbent" TEXT, "Party" TEXT, "First elected" FLOAT, "Result" TEXT)

What district is James Humphrey from who was first elected in 1858 and was eventually defeated democratic gain?
SELECT "District" FROM table_5603 WHERE "First elected" = '1858' AND "Result" = 'defeated democratic gain' AND "Incumbent" = 'james humphrey'
SELECT "District" FROM "table_5603" WHERE "First elected" = '1858' AND "Incumbent" = 'james humphrey' AND "Result" = 'defeated democratic gain'