CREATE TABLE table_14442 ("Player" TEXT, "Position" TEXT, "Round" TEXT, "Overall" FLOAT, "MLB Team" TEXT)

Which position was more than 421 overall for the St. Louis Cardinals?
SELECT "Position" FROM table_14442 WHERE "Overall" > '421' AND "MLB Team" = 'st. louis cardinals'
SELECT "Position" FROM "table_14442" WHERE "MLB Team" = 'st. louis cardinals' AND "Overall" > '421'