In versions 16.0.0-16.0.0.1, 15.1.0-15.1.0.3, 15.0.0-15.0.1.3, 14.1.0-14.1.2.6, and 13.1.0-13.1.3.4, BIG-IP Virtual Edition (VE) systems on VMware, with an Intel-based 85299 Network Interface Controller (NIC) card and Single Root I/O Virtualization (SR-IOV) enabled on vSphere, may fail and leave the Traffic Management Microkernel (TMM) in a state where it cannot transmit traffic.