In F5 BIG-IP systems 12.1.0 - 12.1.2, malicious requests made to virtual servers with an HTTP profile can cause the TMM to restart. The issue is exposed with BIG-IP APM profiles, regardless of settings. The issue is also exposed with the non-default "Normalize URI" configuration options used in iRules and/or BIG-IP LTM policies. An attacker may be able to disrupt traffic or cause the BIG-IP system to fail over to another device in the device group.