신손상,사구체,신염,관절염,기능 저하
이외에도 methyl dpa, chlrprmazine, quinidine, diltiazem, mincy cline, penicillamine, isniazid, rifampin, phenytin, lithium, betablckers, nitrfurantin, captpril, gly buride, hydrchlrthiazide, INFalpha, carbamazepine, sulfasalazine, sulfnamides, prpylthiuracil, naprxen 등이 연관되어 있다.