exhibit 10. 1 december 30, 2021 via email and courier biosight ltd. 3 hayarden st., airport city p. o. b 1083 lod # # # - # # # - # # # # israel e - mail : * * * @ * * * attention : dr. ruth ben yakar dear ruth : i am writing in connection with the agreement and plan of merger and reorganization, dated as of july 4, 2021, among advaxis, inc., advaxis, ltd., and biosight ltd ( the “ agreement ” 1 ). as you know, at the second reconvened advaxis stockholders ’ meeting, advaxis ’ stockholders did not approve proposal 2 relating to the reverse split, which was necessary for advaxis to issue the merger consideration to the biosight shareholders. accordingly, the advaxis stockholder approval, which was a condition to the obligations of each party under the agreement, was not obtained. because the advaxis stockholder approval was not obtained, advaxis hereby terminates the agreement pursuant to section 9. 1 ( b ) ( iv ) of the agreement, effective immediately. we regret that advaxis and biosight were unable to conclude the transactions, but we look forward to opportunities to work with biosight in the future. very truly yours, advaxis, inc. by : / s / kenneth a. berlin name : kenneth a. berlin title : chief executive officer by : / s / kenneth a. berlin by : / s / kenneth a. berlin name : kenneth a. berlin name : kenneth a. berlin title : chief executive officer title : chief executive officer copies to : white & case llp 3000 el camino real, 2 palo alto square, suite 900 palo alto, ca # # # - # # # - # # # # telephone no. : + 1 # # # - # # # - # # # # e - mail : * * * @ * * * attention : tali sealman white & case llp 1221 avenue of the americas new york, ny 10020 - 1095 telephone no. : + 1 # # # - # # # - # # # # e - mail : * * * @ * * * attention : colin diamond horn & co. law offices amot investments tower, 24th floor 2 weizmann st., tel -