exhibit 4. 5 execution copy amended and restated series c warrant agreement dated as of august 27, 2009 exhibit 4. 5 execution copy amended and restated series c warrant agreement dated as of august 27, 2009 table of contents 1. issuance 1 2. definitions and interpretation 1 2. 1 definitions 1 2. 2 interpretations 7 3. exercise of warrant 8 3. 1 exercise 8 3. 2 manner of exercise 8 3. 3 payment of charges 9 3. 4 fractional shares 9 4. transfer, division and combination 9 4. 1 transfer 9 4. 2 division and combination 10 4. 3 expenses 10 4. 4 maintenance of books 10 5. exercise price ; antidilution provisions 10 5. 1 exercise price 10 5. 2 adjustments ; exceptions 10 5. 3 effect on exercise price of certain events 12 5. 4 notices 15 6. no impairment 15 7. reservation and authorization of common stock ; registration with or approval of any governmental authority 16 8. notice of corporate actions ; taking of record ; transfer books 16 8. 1 notices of corporate actions 16 8. 2 taking of record 17 8. 3 closing of transfer books 17 9. transfer restrictions ; legends 17 9. 1 restrictions on transfer and entry into shareholders agreement and registration rights agreement 17 9. 2 legends 18 10. loss or mutilation 19 11. office of the company 20 12. financial and business information 20 12. 1 deliveries 20 12. 2 financial statements 21 table of contents 1. issuance 1 2. definitions and interpretation 1 2. 1 definitions 1 2. 2 interpretations 7 3. exercise of warrant 8 3. 1 exercise 8 3. 2 manner of exercise 8 3. 3 payment of charges 9 3. 4 fractional shares 9 4. transfer, division and combination 9 4. 1 transfer 9 4. 2 division and combination 10 4. 3 expenses 10 4. 4 maintenance of books 10 5. exercise price ; antidilution provisions 10 5. 1 exercise price 10 5. 2 adjustments ; exceptions 10 5. 3 effect on exercise price of certain events 12 5. 4 notices 15 6. no impairment 15 7. reservation and authorization of common stock ; registration with or approval of any governmental authority 16 8. notice of corporate actions ; taking of record ; transfer books 16 8. 1 notices of corporate actions 16 8. 2 taking of record 17 8. 3 closing of transfer books 17 9. transfer restrictions ; legends 17 9. 1 restrictions on transfer and entry into shareholders agreement and