exhibit 10. 1 amendment # 2 to the license, development and commercialization agreement between echo therapeutics, inc. and medical technologies innovations, asia, ltd. 1 executive summary 1 executive summary 1 executive summary 1. 1 scope. this amendment covers the activities necessary to support the chinese commercialization of the “ core 2 + and “ generation 3 ” versions of the echo cgm system, as defined below. this amendment # 2 will take effect, and is conditioned upon receipt of $ 500, 000 in additional bridge loans on or before november 30th. 1. 2 amended terms. the terms in the original agreement remain in force, except as described below. 1. 3 product definition. the definition of “ product ” contained in section 1. 1. 59 is amended to include the following : release device description echo deliverables mtia responsibilities core 2 + system support as needed plus deliverables listed below. evaluation and testing of mtia produced materials, as needed. prototype construction, preliminary clinical testing in china. manufacturing, cfda clinical testing, regulatory approval, commercialization. sensor module & target base gen 1 cophthal electrode, dried hydrogel, plastic case. target base with adhesive. design changes, test reports. final changes to design and testing as needed. disposable kit disposable package, containing the single use devices. updates include new tip, bzk wipe, reference ring & labeling none. update to bill of materials, contents, packaging & labeling. shelf life & other testing as needed. transmitter bluetooth transmitter and embedded firmware. firmware executable program and pc based test program. testing as needed. glucose algorithm signal processing software and configuration parameters. executable program and baseline configuration parameters. pc based test tool. final configuration parameters, testing as needed. exfoliator skin exfoliator, with embedded control firmware and configuration parameters. battery charger. design documentation, sample prototypes. firmware executable program, configuration parameters and pc based test program. final configuration parameters, testing as needed. exfoliator tip production. battery charger design, development and testing. api application programming interface, running on android executable software ( android ), test reports and interface document. none. app cgm application with graphical user interface. example english app with source code and executable ( android ). software development of chinese app, testing as needed. release release device device description description echo deliverables echo deliver