exhibit 10. 31 license, development and commercialization agreement between echo therapeutics, inc. and medical technologies innovation asia, ltd. license, development and commercialization agreement between echo therapeutics, inc. and medical technologies innovation asia, ltd. - 1 - - 1 - - 1 - table of contents 1. definitions. 1. 1. 1. 1 defined terms 1. 1 1. 1 2. development project. 2. 2. 2. 1 commencement of the project 2. 1 2. 1 2. 2 amendments to the work plan 2. 2 2. 2 2. 3 transfer of echo materials and echo know - how 2. 3 2. 3 2. 4 performance by mtia 2. 4 2. 4 2. 5 disclosure of results 2. 5 2. 5 2. 6 reports 2. 6 2. 6 2. 7 storage and maintenance of data 2. 7 2. 7 2. 8 mtia contractors 2. 8 2. 8 3. joint steering committee. 3. 3. 3. 1 joint steering committee 3. 1 3. 1 3. 2 subcommittee. 3. 2 3. 2 3. 3 responsibilities of the joint steering committee 3. 3 3. 3 3. 4 restrictions on the jsc 3. 4 3. 4 4. clinical trials and regulatory submissions 4. 4. 4. 1 conduct of clinical trials 4. 1 4. 1 4. 2 ownership of clinical trial data 4. 2 4. 2 4. 3 access and exchange of information and data 4. 3 4. 3 4. 4 regulatory submissions 4. 4 4. 4 4. 5 meetings and correspondence with regulatory authorities 4. 5 4. 5 5. manufacture, supply and commercialization of product. 5. 5. 5. 1 manufacture of product 5. 1 5. 1 5. 4 joint commercialization committee 5. 4 5. 4 5. 5 role and responsibilities of the joint commercialization committee 5. 5 5. 5 5. 6 development and commercialization costs 5. 6 5. 6 6. regulatory matters. 6. 6. 6. 1 inspections, audits 6. 1 6. 1 6. 2 communications with regulatory authorities 6. 2 6. 2 6. 3 medical device reporting events. 6. 3 6. 3 6. 4 medical inquiries 6. 4 6. 4 6. 5 product complaints 6. 5 6. 5 6. 6 recalls. 6. 6 6. 6 6. 7 regulatory inspections ; inquiries.