by . emma innes . heat makes ecstasy more lethal , new research suggests . u.s. researchers found doses of mdma that would not be fatal in cool conditions , can kill people when taken in hot , crowded settings such as nightclubs . this is because the drug interferes with the body 's ability to regulate temperature . even moderate doses of mdma can be fatal in warm environments , such as nightclubs -lrb- file picture -rrb- . by . simon cable . published : . 20:58 est , 24 february 2013 . by . mark prigg . published : . 11:34 est , 7 november 2012 . | . | . updated : . 12:04 est , 7 november 2012 . scientists working with nasa 's 230-foot-wide -lrb- 70-meter -rrb- deep space network antenna at goldstone in california have revealed radar images of a near earth asteroid as is approached us just days ago . near-earth asteroid 2007 pa8 passed by on oct. 28 , 29 and 30 . updated : . 03:53 est , 25 february 2013 . even though she followed a gruelling diet to shed more than 7st in a year , dawn french admits she is happier now she has piled on the pounds again . the comedienne , 55 , went on a strict regime that included cutting out chocolate and carbohydrates after her 25-year marriage to lenny henry ended in 2010 . but she has recently put 2st back on -- and says she feels more dignified and ` in control ' . ` if you 've got the gift of a bit of extra heft , use it , ' miss french told australia 's new idea magazine . researchers at the national institute of health say some people believe mdma is harmless when taken in moderate doses . but , their new research in rats showed this is not the case in hot environments . ` we know that high doses of mdma can sharply increase body temperature to potentially lead to organ failure or even death , ' said dr nora volkow . ` however , this current study opens the possibility that even moderate doses could be deadly in certain conditions . ' the researchers say it is currently impossible to predict who will have an adverse reaction to a low dose of mdma . dawn french shed 7st after cutting down on carbohydrates and chocolate having peaked at about 19st . ` i 'd like to decide what you may find funny about my fatness . for me there 's a dignity in that . ` i do n't need you to be laughing at my fatness in a cruel or bullying way . luckily in my life i 've never experienced that , but i know that other big women do and do n't like it at all . i 've always wrestled that into my control . ' miss french , who is to star with james corden in the bbc2 comedy the wrong mans , was 19st at her heaviest . she blames her recent weight gain on a weakness for bread , pasta and potatoes . the asteroid 's distance from earth on oct. 28 was 6.5 million miles -lrb- 10 million kilometers -rrb- , and 5.6 million miles -lrb- 9 million kilometers -rrb- on oct. 30 , and it made its closest approach on november 5th , coming within 17 times the earth-moon distance -lrb- 4 million miles or 6.5 million kilometers -rrb- . ` i had ballooned a bit more than i wanted to . i want to be there for my kid , ' she added . this composite image of asteroid 2007 pa8 was obtained using data taken by nasa 's 230-foot-wide -lrb- 70-meter -rrb- deep space network antenna at goldstone , calif. . jpl scientists chose to image asteroid . 2007 pa8 due to its size and relative proximity to earth at the point . of closest approach . the perspective in the images is similar to seeing the asteroid from above its north pole . each of the three images is shown at the same scale , nasa said . ` the radar images of asteroid 2007 pa8 indicate that it is an elongated , irregularly shaped object approximately one mile -lrb- 1.6 kilometers -rrb- wide , with ridges and perhaps craters . ` the data also indicate that 2007 pa8 rotates very slowly , roughly once every three to four days . ' the vicar of dibley actress , who began . dating twice-married charity executive mark bignell , 49 , last year , has . ruled out any more diets in the future , saying she has come to terms . with her figure . however in this study , scientists gave the rats low to moderate doses that have been shown in past studies to not be fatal . the drug interferes with the body 's ability to regulate temperature so is dangerous in warm environments . they monitored the rats to determine drug-induced changes in brain and body temperature and in the body 's ability to cool itself through blood vessel dilation . ` i am perfectly happy with how i look and i always have been . i 'll . always be a fat girl and i am happy with that , ' she said recently . the comedienne has found love again with charity chief executive mark bignell after splitting from lenny henry after 25 years of marriage . in interviews at the time she said that entering her fifties had made her more health conscious . when rats were alone and kept at room temperature , a moderate dose of mdma modestly increased brain and body temperature and moderately diminished the rats ' ability to eliminate excessive heat . however , when researchers injected the same dose into rats that were either in a warmer environment or in the presence of another rat in the cage , brain temperature increased , causing death in some rats . ` these results demonstrate that the use of mdma in certain warm , social settings could be more dangerous than commonly believed , ' said dr eugene kiyatkin , first author on the study . ` even with moderate doses , we saw drug-induced , fatal brain hyperthermia during conditions of social interaction and in warm environments . ' miss french also explained that falling in love has given her a new lease of life , and suggested that she started to put the weight back on following a romantic trip to paris with mr bignell . ` generally i eat much more healthily and i eat less , probably half as much as i did before , ' she said . ` i am very fond of this body - it 's served me well and it 's never disappointed me . ` i understand it , i know it and i even like it now it 's all saggy , it 's a mark of my journey this far . ' mr bignell , whom miss french has described as a ` remarkable man ' , is chief executive of a plymouth-based charity which helps drug and alcohol abusers reintegrate into society . the trajectory of asteroid 2007 pa8 is well understood . this flyby was the closest earth approach by this asteroid for at least the next 200 years . although the orbit of 2007 pa8 is well known and is not considered a threat to earth in the near-term , it is classified as a ` near-earth asteroid . ' the images were taken as part of nasa 's spaceguard project to watch for steroids and other objects that could hit earth . the goldstone observations are a part of nasa 's near-earth object observations program , or ` spaceguard , ' where objects are discovered , characterized and tracked . spaceguard identifies potential threats to our planet .
near-earth asteroid 2007 pa8 passed by on october 28 , 29 and 30 . made its closest approach on november . 5 , coming within 17 times the earth-moon distance -lrb- 4 million miles or . 6.5 million kilometers -rrb- .
by . emma innes . heat makes ecstasy more lethal , new research suggests . u.s. researchers found doses of mdma that would not be fatal in cool conditions , can kill people when taken in hot , crowded settings such as nightclubs . this is because the drug interferes with the body 's ability to regulate temperature . even moderate doses of mdma can be fatal in warm environments , such as nightclubs -lrb- file picture -rrb- . by . simon cable . published : . 20:58 est , 24 february 2013 . by . mark prigg . published : . 11:34 est , 7 november 2012 . | . | . updated : . 12:04 est , 7 november 2012 . scientists working with nasa 's 230-foot-wide -lrb- 70-meter -rrb- deep space network antenna at goldstone in california have revealed radar images of a near earth asteroid as is approached us just days ago . near-earth asteroid 2007 pa8 passed by on oct. 28 , 29 and 30 . updated : . 03:53 est , 25 february 2013 . even though she followed a gruelling diet to shed more than 7st in a year , dawn french admits she is happier now she has piled on the pounds again . the comedienne , 55 , went on a strict regime that included cutting out chocolate and carbohydrates after her 25-year marriage to lenny henry ended in 2010 . but she has recently put 2st back on -- and says she feels more dignified and ` in control ' . ` if you 've got the gift of a bit of extra heft , use it , ' miss french told australia 's new idea magazine . researchers at the national institute of health say some people believe mdma is harmless when taken in moderate doses . but , their new research in rats showed this is not the case in hot environments . ` we know that high doses of mdma can sharply increase body temperature to potentially lead to organ failure or even death , ' said dr nora volkow . ` however , this current study opens the possibility that even moderate doses could be deadly in certain conditions . ' the researchers say it is currently impossible to predict who will have an adverse reaction to a low dose of mdma . dawn french shed 7st after cutting down on carbohydrates and chocolate having peaked at about 19st . ` i 'd like to decide what you may find funny about my fatness . for me there 's a dignity in that . ` i do n't need you to be laughing at my fatness in a cruel or bullying way . luckily in my life i 've never experienced that , but i know that other big women do and do n't like it at all . i 've always wrestled that into my control . ' miss french , who is to star with james corden in the bbc2 comedy the wrong mans , was of mdma in certain warm , social settings could be more dangerous than commonly believed , ' said dr eugene kiyatkin , first author on the study . ` even with moderate doses , we saw drug-induced , fatal brain hyperthermia during conditions of social interaction and in warm environments . ' miss french also explained that falling in love has given her a new lease of life , and suggested that she started to put the weight back on following a romantic trip to paris with mr bignell . ` generally i eat much more healthily and i eat less , probably half as much as i did before , ' she said . ` i am very fond of this body - it 's served me well and it 's never disappointed me . ` i understand it , i know it and i even like it now it 's all saggy , it 's a mark of my journey this far . ' mr bignell , whom miss french has described as a ` remarkable man ' , is chief executive of a plymouth-based charity which helps drug and alcohol abusers reintegrate into society . the trajectory of asteroid 2007 pa8 is well understood . this flyby was the closest earth approach by this asteroid for at least the next 200 years . although the orbit of 2007 pa8 is well known and is not considered a threat to earth in the near-term , it is classified as a ` near-earth asteroid . ' the images were taken as part of nasa 's spaceguard project to watch for steroids and other objects that could hit earth . the goldstone observations are a part of nasa 's near-earth object observations program , or ` spaceguard , ' where objects are discovered , characterized and tracked . spaceguard identifies potential threats to our planet .
230-foot-wide -lrb- 70-meter -rrb- deep space network antenna at goldstone in california have revealed radar images of a near earth asteroid as is approached us just days ago . near-earth asteroid 2007 pa8 passed by on oct. 28 , 29 and 30 . updated : . 03:53 est , 25 february 2013 . even though she followed a gruelling diet to shed more than 7st in a year , dawn french admits she is happier now she has piled on the pounds again . the comedienne , 55 , went on a strict regime that included cutting out chocolate and carbohydrates after her 25-year marriage to lenny henry ended in 2010 . but she has recently put 2st back on -- and says she feels more dignified and ` in control ' . ` if you 've got the gift of a bit of extra heft , use it , ' miss french told australia 's new idea magazine . researchers at the national institute of health say some people believe mdma is harmless when taken in moderate doses . but , their new research in rats showed this is not the case in hot environments . ` we know that high doses of mdma can sharply increase body temperature to potentially lead to organ failure or even death , ' said dr nora volkow . ` however , this current study opens the possibility that even moderate doses could be deadly in certain conditions . ' the researchers say it is currently impossible to predict at goldstone , calif. . jpl scientists chose to image asteroid . 2007 pa8 due to its size and relative proximity to earth at the point . of closest approach . the perspective in the images is similar to seeing the asteroid from above its north pole . each of the three images is shown at the same scale , nasa said . ` the radar images of asteroid 2007 pa8 indicate that it is an elongated , irregularly shaped object approximately one mile -lrb- 1.6 kilometers -rrb- wide , with ridges and perhaps craters . ` the data also indicate that 2007 pa8 rotates very slowly , roughly once every three to four days . ' the vicar of dibley actress , who began . dating twice-married charity executive mark bignell , 49 , last year , has . ruled out any more diets in the future , saying she has come to terms . with her figure . however in this study , scientists gave the rats low to moderate doses that have been shown in past studies to not be fatal . the drug interferes with the body 's ability to regulate temperature so is dangerous in warm environments . they monitored the rats to determine drug-induced changes in brain and body temperature and in the body 's ability to cool itself through blood vessel dilation . ` i am perfectly happy with how i look and i always have been . i 'll . always be a fat girl and i am happy with that , ' she said recently . the comedienne has found love again with charity chief executive mark bignell after splitting from lenny henry after 25 years of marriage . in interviews at the time she said that entering her fifties had made her more health conscious . when rats were alone and kept at room temperature , a moderate dose of mdma modestly increased brain and body temperature and moderately diminished the rats ' ability to eliminate excessive heat . however , when researchers injected the same dose into rats that were either in a warmer environment or in the presence of another rat in the cage , brain temperature increased , causing death in some rats . ` these results demonstrate that the use of mdma in certain warm , social settings could be more dangerous than commonly believed , ' said dr eugene kiyatkin , first author on the study . ` even with moderate doses , we saw drug-induced , fatal brain hyperthermia during conditions of social interaction and in warm environments . ' miss french also explained that falling in love has given her a new lease of life , and suggested that she started to put the weight back on following a romantic trip to paris with mr bignell . ` generally i eat much more healthily and i eat less , probably half as much as i did before , ' she said . ` i am very fond of this body - it 's served me well and it 's never disappointed me . ` i understand it , i know it and i even like it now it 's all saggy , it 's a mark of my journey this far . ' mr bignell , whom miss french has described as a ` remarkable man ' , is chief executive of a plymouth-based charity which helps drug and alcohol abusers reintegrate into society . the trajectory of asteroid 2007 pa8 is well understood . this flyby was the closest earth approach by this asteroid for at least the next 200 years . although the orbit of 2007 pa8 is well known and is not considered a threat to earth in the near-term , it is classified as a ` near-earth asteroid . ' the images were taken as part of nasa 's spaceguard project to watch for steroids and other objects that could hit earth . the goldstone observations are a part of nasa 's near-earth object observations program , or ` spaceguard , ' where objects are discovered , characterized and tracked . spaceguard identifies potential threats to our planet .
by. emma innes. heat makes ecstasy lethal, new research u.s. researchers found doses mdma would fatal cool conditions, can people when hot, crowded settings such. this because the drug temperature. even moderate doses mdma can warm environments, such nightclubs -lrb- file picture -rrb-. by. simon cable. published :. 20:58 est, 24 february. by. mark prigg. published :. 11:34 est, 7 november. |. |. updated :. 12:04 est, 7 november. scientists working nasa 's 230 -lrb- 70 -rrb- deep network antenna at goldstone have revealed radar images a near earth asteroid as is approached us just days ago. near-earth 2007 pa8 passed oct. 28, and updated :. 03:53 est, 25 february. even she followed a gruelling diet shed more 7st in, dawn french admits happier piled again the comedienne, 55 went a strict regime that included cutting chocolate carbohydrates after lenny henry ended 2010 but she recently put 2st back -- says feels more dignified ` in '. ` if 've the gift a bit extra heft, use, miss french told australia 's new idea magazine. the national institute say some people believe mdma harmless when. but, their new research in rats this in hot environments ` we know high doses mdma sharply body temperature to potentially lead organ, ' dr nora volkow. ` however this current study opens even moderate doses could deadly certain conditions ' the researchers currently who have mdma. dawn french shed 7st after cutting carbohydrates chocolate having peaked about 19st. ` i 'd decide you may find funny my fatness. for me there 's a dignity. ` i do n't need laughing my fatness in cruel or bullying. luckily in my life i ' experienced that, other big women do n't at. i 've always wrestled that into. ' miss french, who to star with james corden the bbc2 comedy the wrong mans, was 19st at her heaviest. she blames her recent weight gain a weakness bread, pasta potatoes the asteroid 's distance on oct. 28 was 6.5 million miles -lrb- 10 million kilometers, and on oct. 30, and it made its closest approach on november 5th, coming 17 times the earth-moon distance -lrb- 4 million miles or ` i had ballooned a more. i want there my kid, ' she added this composite image asteroid 2007 pa8 was obtained data taken nasa 's 230 -lrb- 70-meter -rrb- deep space network antenna goldstone,. . jpl scientists chose image asteroid. 2007 pa8 due its size relative proximity earth at. of closest approach. the perspective in the images similar seeing the asteroid from its north pole. each the three images is shown, nasa. ` the radar images asteroid 2007 pa8 indicate an elongated, irregularly shaped object approximately one -lrb- 1.6 -rrb- wide, perhaps craters. ` the data also indicate that 2007 pa8 rotates very, roughly once three ' the vicar dibley actress, began. dating twice-married charity executive mark bignell, 49 last has. ruled any more diets in, saying she has come. with her figure. however in this study, scientists gave low to that have in past studies not fatal the drug temperature so is dangerous in warm environments. they monitored the rats drug-induced changes and in the body 's ability cool itself through blood vessel dilation. ` i am perfectly how look i always. i 'll. always be a fat girl i happy, ' she recently the comedienne has found love again charity chief executive mark bignell after splitting lenny henry after. in interviews at she entering her more health. when rats alone kept, a moderate dose mdma modestly brain and moderately diminished the rats ' ability eliminate excessive heat however, when researchers injected the same dose either in a warmer environment another rat in brain temperature, causing death ` these results demonstrate mdma in certain warm, social settings could more dangerous commonly, ' said dr eugene kiyatkin first author on ` even with moderate doses, we saw drug-induced, fatal brain hyperthermia during conditions social interaction warm environments ' miss french also explained that falling has given, suggested started put the weight back following a romantic trip paris with mr bignell ` generally i eat much healthily, probably half ' she. ` i am very fond this body - 's served never disappointed. ` i understand, know and even now it 's all saggy a mark my journey this far. ' mr bignell, whom miss french has described a ` remarkable man chief executive a plymouth-based charity helps drug and alcohol abusers the trajectory asteroid 2007 pa8 is well understood. this flyby the closest earth approach by this asteroid for. although the orbit 2007 pa8 well considered a threat earth in, classified a ` near-earth asteroid. ' the images as nasa 's spaceguard project watch steroids other objects hit earth. the goldstone observations are a part nasa 's near-earth object observations program, or ` spaceguard where objects discovered, characterized tracked spaceguard identifies potential threats.
by . emma innes . heat makes ecstasy more lethal , new research suggests . u.s. researchers found doses of mdma that would not be fatal in cool conditions , can kill people when taken in hot , crowded settings such as nightclubs . this is because the drug interferes with the body 's ability to regulate temperature . even moderate doses of mdma can be fatal in warm environments , such as nightclubs -lrb- file picture -rrb- . by . simon cable . published : . 20:58 est , 24 february 2013 . by . mark prigg . published : . 11:34 est , 7 november 2012 . | . | . updated : . 12:04 est , 7 november 2012 . scientists working with nasa 's 230-foot-wide -lrb- 70-meter -rrb- deep space network antenna at goldstone in california have revealed radar images of a near earth asteroid as is approached us just days ago . near-earth asteroid 2007 pa8 passed by on oct. 28 , 29 and 30 . updated : . 03:53 est , 25 february 2013 . even though she followed a gruelling diet to shed more than 7st in a year , dawn french admits she is happier now she has piled on the pounds again . the comedienne , 55 , went on a strict regime that included cutting out chocolate and carbohydrates after her 25-year marriage to lenny henry ended in 2010 . but she has recently put 2st back on -- and says she feels more dignified and of mdma in certain warm , social settings could be more dangerous than commonly believed , ' said dr eugene kiyatkin , first author on the study . ` even with moderate doses , we saw drug-induced , fatal brain hyperthermia during conditions of social interaction and in warm environments . ' miss french also explained that falling in love has given her a new lease of life , and suggested that she started to put the weight back on following a romantic trip to paris with mr bignell . ` generally i eat much more healthily and i eat less , probably half as much as i did before , ' she said . ` i am very fond of this body - it 's served me well and it 's never disappointed me . ` i understand it , i know it and i even like it now it 's all saggy , it 's a mark of my journey this far . ' mr bignell , whom miss french has described as a ` remarkable man ' , is chief executive of a plymouth-based charity which helps drug and alcohol abusers reintegrate into society . the trajectory of asteroid 2007 pa8 is well understood . this flyby was the closest earth approach by this asteroid for at least the next 200 years . although the orbit of 2007 pa8 is well known and is not considered a threat to earth in the near-term , it is classified as a ` near-earth asteroid . ' the images were taken as part of nasa 's spaceguard project to watch for steroids and other objects that could hit earth . the goldstone observations are a part of nasa 's near-earth object observations program , or ` spaceguard , ' where objects are discovered , characterized and tracked . spaceguard identifies potential threats to our planet .
 Researchers have found that MDMA, also known as ecstasy, can be fatal in hot and crowded settings. The drug interferes with the body's ability to regulate temperature, leading to overheating and potentially life-threatening conditions. Even moderate doses of MDMA can cause dangerous increases in body temperature, especially when combined with physical activity and warm environments. This research highlights the importance of educating users about the risks associated with MDMA use, particularly in situations where they may be more susceptible to heat-related illnesses.