text: Yo, check it out, I got some knowledge to drop
  'Bout them cells, ASCs, straight from the top
  Derived from adipose, they adapt to a niche
  With low oxygen tension, that's the switch
  
  Hypoxia, that's the game they play
  In the body, where they stay
  Oxygen tension, it's no joke
  It's crucial for stem cells, that's the truth they spoke
  
  But the effect of O2 tension, still a mystery
  On their functional properties, it's all history
  So we dug in deep, in this study we went
  Investigating ASCs, how they're bent
  
  Normoxia, that's 21% O2
  Hypoxia, we took it down a few
  2% O2, that's the deal
  We wanted to see how ASCs would feel
  
  And we found something, it was quite profound
  Hypoxia increased stemness, it's renowned
  Marker expression, it went up high
  Proliferation rate, it reached for the sky
  
  Morphology and surface markers, they stayed the same
  Under low oxygen tension, no need to change
  But chondrogenic differentiation, it got a boost
  Adipogenic and osteogenic, they were reduced
  
  HIF-1α, it played a role
  Increased expression, that's the goal
  Putting it all together, here's the scoop
  Growing ASCs at 2% O2, it's a group
  
  Expanding them effectively, that's the key
  Maintaining their properties, you see
  For clinical therapy, it's the way to go
  Treating cartilage defects, watch 'em grow