text: Yo, check it out, let me break it down for you,
  Talkin' 'bout transmissible spongiform encephalopathies, it's true,
  The host got this protein called PrP-sen, you see,
  But it converts to PrP-res, a pathologic MC,
  PrP-res got that proteinase K resistance, can't be tamed,
  Insolubility and beta sheet content, it's untamed.
  
  Now, we wanna know if them aspartyl or asparaginyl residues,
  With D-aspartate and L-isoaspartate, they got some clues,
  Could they be playin' a role in PrP-res formation or stability?
  So we checked for abnormal residues, let's see what we see.
  
  We used the Protein D-aspartyl/L-isoaspartyl carboxyl methyltransferase,
  Methylated and radiolabeled them altered residues with finesse,
  And we found 'em in PrP-res, but at low levels, you know,
  Only 0.5 mole percent, they ain't stealin' the show.
  
  Seems like D-aspartyl and L-isoaspartyl groups ain't the main game,
  They ain't the reason why PrP-res and PrP-sen ain't the same,
  But hey, there's still a chance, just a small fraction might be,
  Helpin' initiate PrP-res formation or stabilizin' it, can't you see?
  
  So there you have it, the science in a rap,
  TSE, PrP-sen, PrP-res, it's a crazy trap,
  Alterations and modifications, tryna find the key,
  To understand these diseases, that's the mission, G, believe me!