text: Yo, check it out, let me break it down
  Talkin' 'bout P-glycoprotein's ATPase activity, how it gets down
  Insect cells were used, no tricks or lies
  To study modulation, keep your eyes on the prize
  
  Recombinant baculovirus expressed human Pgp in Sf9
  Pgp teamed up with PKC alpha and PKC epsilon, feelin' so fine
  ATPase assays showed Pgp's enzyme activity on the rise
  With PKC alpha, the Ca2+-dependent isoform, it could fly high
  
  But the Ca2+-independent PKC epsilon didn't have the same effect
  No elevation of Pgp's activity, no respect
  Neither isoform changed the swelling-activated 125I efflux
  No alterations, no flux, no fuss
  
  But hold up, there's more to the story, listen close
  When Pgp/PKC (alpha or epsilon) were co-expressed, it's time to boast
  Pre-treatment with phorbol ester TPA in the mix
  Reduced the swelling-activated 125I efflux, now that's the fix
  
  So, in conclusion, Ca2+-independent PKC epsilon ain't the key
  To regulate Pgp's ATPase activity, can't you see?
  But when PKC gets stimulated by TPA, that's the deal
  Swelling-activated anion efflux in insect cells, it's for real