text: Neuropathic pain, yo, it's a real struggle,
  Affects 7-10% of the population, causing trouble.
  Treating it ain't easy, that's for sure,
  Therapeutics from animal models ain't findin' a cure.
  
  Clinical trials failed, couldn't make the leap,
  Suggestin' differences 'tween animals and humans run deep.
  To bridge the gap, we gotta study human cells,
  Understand the variances, break the spell.
  
  So we did some patch-clamp electrophysiology,
  And RNA-sequencing, checkin' the biology.
  Took dorsal root ganglia from patients in pain,
  With radicular/neuropathic symptoms, the strain.
  
  What did we find? Spontaneous action potential,
  In the neurons, correlated with pain, it's essential.
  Transcriptome analysis showed sex-specific genes,
  And pathways related to immune response, so it seems.
  
  Neuronal plasticity, a key player in the game,
  Signaling pathways hold the potential for fame.
  Therapeutic avenues, they might unveil,
  Predictin' neuropathic pain in future, no fail.