text: Yo, let me drop some knowledge on the metabolism of leukotriene, alright?
  We studied it using bioassay and RP-HPLC, tight.
  We took 20,000 g supernatants, homogenates from adult lung,
  Incubated with LTA4 and LTC4, see what it brung.
  
  After some time, we saw substances with higher activity,
  Compared to controls, man, it was a real festivity.
  We measured it on guinea pig lung and ileum strips,
  The results were off the charts, no time for quips.
  
  RP-HPLC analysis showed the formation of some dope,
  LTB4, LTC4, LTD4, and LTE4, giving us hope.
  LTA4 transformed into LTB4, that's the key,
  LTC4 gave us LTD4 and LTE4, can't you see?
  
  LTD4 was converted to LTE4, a smooth transition,
  But LTB4 and LTE4 didn't undergo much fission.
  During a 2-hour incubation, they stayed intact,
  Not breaking down, that's a scientific fact.
  
  We also checked out fetal lung homogenates, my friend,
  They had enzymatic activities, let me comprehend.
  LTC4 transformed into LTD4 and LTE4, that's true,
  But LTA4 was all about LTB4, that's what it would do.
  
  We found some nonenzymatic hydrolysis going on,
  Delta 6-trans-LTB4, delta 6-trans-12-epi-LTB4, it's drawn.
  And let's not forget the 5,6-dihyroxyeicosatetraenoic acids,
  Peptidoleukotrienes were formed, but in smaller amounts, just a tad.
  
  So that's the rap on leukotriene metabolism, my friend,
  Bioassay and RP-HPLC, we reached the end.
  Now you know the deal, the info's in your brain,
  Stay curious, keep learning, and you'll never be the same.