text: Yo, check it out, I got a story to tell,
  'Bout Paraoxonase 1, let me break the spell.
  It's a enzyme that breaks down toxic compounds,
  Reduces lipids peroxides, keeps us safe and sound.
  
  Now let's talk genetics, PON1's got some tricks,
  Polymorphisms in the coding region, that's the mix.
  In this study, we investigated the scene,
  Three polymorphisms, let me make it clean.
  
  Intron 5 holds 17899insdelTT and 17974CT,
  Exon 6 got 192QR, you best believe.
  We checked 'em out in 153 healthy Koreans,
  Sequencing and spectrophotometry, that's how we glean.
  
  Linkage disequilibrium, it's a real thing,
  Strongest between 17899insdelTT and 192QR, let it ring.
  These polymorphisms affect PON1's activity,
  Serum paraoxonase, let's break it down with clarity.
  
  Multiple regression came through with the facts,
  Smoking, triglycerides, HDL, that's the stack.
  17899insdelTT and 192QR, they play a role,
  Determining serum paraoxonase, that's the goal.
  
  But wait, there's more, arylesterase in the mix,
  Age, smoking, triglycerides, HDL, it's a fix.
  192QR, the genetic polymorphism's in play,
  Determining serum arylesterase, day by day.
  
  So, here's the deal, the 192QR's the star,
  But intronic polymorphisms also play a part.
  They're linked together, that's the way it goes,
  PON1 activity, influenced by the highs and lows.