text: Yo, check it out, vascularization is the key
  To regenerate tissue, that's what we need, you see
  Implants delivering VEGF, that's the deal
  Angiogenic factors, making blood vessels real
  
  In this study, we aimed to find out
  If VEGF in nanoparticles could bring about
  Enhanced angiogenesis in a live situation
  Compared to free VEGF, a new revelation
  
  We used two different 3D matrices, you know
  Matrigel™ hydrogels and PLGA scaffolds, let's go
  Negatively charged nanoparticles, that's the trick
  Encapsulated VEGF, making it stick
  
  Dextran sulfate and chitosan, they came into play
  Forming complexes, nanoparticles all the way
  After two weeks, we saw a change in release
  Less VEGF from hydrogels, more from the beasts
  
  Encapsulation boosted VEGF's effect
  Reducing release from the hydrogels, that's correct
  From 30% to just 1%, it was controlled
  And from the scaffolds, release increased, behold
  
  From 20% to 30%, a significant gain
  Encapsulated VEGF, breaking free from the chain
  In vivo, we witnessed the power of this method
  Angiogenesis improved, yo, you gotta accept it
  
  Up to 7.5 to 3.5 times more cells we found
  Endothelial and red blood cells, all around
  In the hydrogels and scaffolds, they thrived
  Encapsulated VEGF made sure they survived
  
  So, yo, encapsulation in nanoparticles, it's the way
  Enhancing VEGF's efficiency, that's what we say
  Protection and controlled release, the implants bring
  Tissue regeneration engineering, let it ring