text: Yo, check it out, I got a tale to tell,
  'Bout symptomatic splenomegaly, straight from hell,
  It's a challenge, myelofibrosis, what a mess,
  Got constitutional symptoms and anemia, no rest.
  
  Cytopenias makin' treatment tough to handle,
  Current therapies just make 'em scramble,
  Hydroxyurea's the first line, gotta try,
  But it only works for 'bout 40%, oh my!
  
  Immunomodulatory drugs like thalidomide and lenalidomide,
  Don't do much to reduce that splenomegaly stride,
  Surgery's an option for the ones who fail,
  But the risks are high, can't just sail.
  
  Radiotherapy brings some relief, it's true,
  But it can also cause cytopenias to accrue,
  Stem cell transplantation, the ultimate cure,
  But it's limited to those with risks obscure.
  
  Now listen up, here's where things get tight,
  JAK2 inhibitors, they shine so bright,
  Palliative, yes, but they show some hope,
  Changing the game, new therapeutic scope.
  
  So remember this rap when you hear the news,
  Myelofibrosis ain't no walk in the shoes,
  But with advancements and JAK2 inhibitors in sight,
  We're ready to fight and change the game, alright!