text: Immunoglobulin G, yo, that's IgG,
  It's got functions immune, let me break it down, you see.
  Complement and cellular receptors, FcγR,
  That's how it does its job, takin' it far.
  
  Now IgG's got a glycan, N-linked at Asn297,
  Evolutionary conserved, gotta keep it steady.
  This glycan's got fucose, galactose, and sialic acid,
  And bisecting N-acetylglucosamine, gettin' it rad.
  
  But check it, the lack of fucose, that's the key,
  It enhances binding to FcγRIII, can't you see?
  Therapeutic monoclonal antibodies, they know the deal,
  They use this trick to improve efficacy, that's the real deal.
  
  But what 'bout the other glycan traits? We ain't got a clue,
  Lack of tools, holdin' us back, that's true.
  But listen up, I got methods, eukaryotic cells in the mix,
  Produce any desired glycoform, fixin' the glitches.
  
  Decoy substrates to decrease fucosylation and galactosylation,
  Transiently overexpressin' glycosyltransferases, that's the revelation.
  Enhancin' bisection, galactosylation, and sialylation too,
  And in vitro sialylation, we know what to do.
  
  With these techniques combined, we're gonna explore,
  The biological effect of these glycosylation traits, and more.
  Not just for IgG, but other glycoproteins in the game,
  We're takin' it to the next level, ain't that insane?