text: Yo, check it out, I'm 'bout to drop some knowledge,
  'Bout Pantothenate kinase, PanK, that's the college.
  It's a regulatory enzyme, controlling CoA,
  Biosynthesis in the house, that's how it go.
  
  Neurodegeneration, diabetes, they're in the mix,
  PanK linked to 'em, like a rhyme to a sick beat, that's the fix.
  So we went high throughput, screenin' compounds galore,
  Over 520,000, from the St. Jude compound store.
  
  We found some new inhibitors, and activators too,
  With chemically tractable scaffolds, makin' moves.
  The HTS, it pinpointed those PanK inhibitors,
  One in particular, let me give you the deets, no quitters.
  
  A tricyclic compound, number seven on the list,
  Detailed characterization, it's the real deal, no twist.
  And we got a preliminary SAR, that's short for structure-activity relationship,
  Studyin' how these compounds work, it's a true partnership.
  
  Biophysical studies show, the PanK inhibitor's game,
  It binds to the ATP-enzyme complex, that's its claim to fame.
  So now we got potential therapeutics on the rise,
  Thanks to chemical modifiers, we're reachin' new skies.