text: Yo, check it out, listen up, I got something to say,
  About the TRPV ion channels that come into play.
  They respond to stimuli, sensory in their might,
  Heat, low pH, neuropeptides, and ligands that excite.
  
  Every TRPV subfamily member got a domain,
  Ankyrin repeat, N-terminal, that's their claim to fame.
  Protein interaction motif, it's prevalent, you see,
  In the structure of TRPV2-ARD, crystal clear to me.
  
  Crystal structure, 1.6-A, let me break it down,
  TRPV2-ARD with ankyrin repeats all around.
  Unusual features, let me give you the scoop,
  Long and flexible fingers, aromatic residues in a group.
  
  Repeats one to three, they got fingers that extend,
  Exposed aromatics, their style don't bend.
  Repeats five and six, outer helices so long,
  Structural anomalies, they stand out strong.
  
  But wait, there's more, let me lay it out straight,
  Repeats four and five, they twist and deviate.
  Counterclockwise motion, breaking the norm,
  Changing the shape, disrupting the form.
  
  Surfaces for interaction, they ain't the same,
  Proteins and ligands got a different game.
  No homo-oligomers, that's the conclusion,
  TRPV2-ARD ain't promoting tetrameric fusion.
  
  Instead, it's all about the regulatory factors,
  ARD's for interactions, like skilled actors.
  TRPV ion channels got a different role,
  Using the ARD domain to maintain control.