text: Yo, listen up, I got something to say,
  'Bout hyperthermia, heatin' up tumors all day.
  For almost forty years, it's been in the game,
  Boostin' radiotherapy and chemo, bringin' the flame.
  
  In this review, we'll discuss the clinical results,
  How it enhances treatment, breakin' the rules.
  Molecular and biological rationale we explore,
  Through in vitro and in vivo, we'll learn more.
  
  Different mechanisms come into play,
  DNA repair inhibition, holdin' tumors at bay.
  Reducin' hypoxia, direct or indirect,
  Enhanced drug uptake, that's what we expect.
  
  Increased perfusion and oxygen, that's the key,
  All these factors workin' together, can't you see?
  But the dose and timing, they gotta be right,
  To optimize the treatment, day and night.
  
  We need more data, details and such,
  On dose, sequence, duration, and the clutch,
  Of synergies between modalities, we gotta know,
  To achieve that ideal treatment, let it show.
  
  A multidisciplinary approach, that's the deal,
  With hyperthermia and other methods that heal.
  Increasin' anti-tumor effects, reducin' the harm,
  Findin' that balance, keepin' patients calm.