text: Yo, check it out, here's the lowdown, listen close
  Gastrointestinal stromal tumors, they're a force
  Spontaneous or inherited, that's the deal
  KIT and PDGFRA mutations, they're real
  
  Most GISTs, they got these oncogenic mechanisms
  But a small subset, they ain't got none of 'em
  Besides Familial GIST Syndrome, understand?
  GIST can be part of a multi-neoplastic plan
  
  Now we gonna analyze tumors that arise
  Synchronous and metachronous, it's no surprise
  In GIST patients, we gonna take a look
  At our institution, GIST Syndrome's the hook
  
  We recruited 141, let me break it down
  77 men, 64 women, hold your ground
  From '88 to '07, that's the time span
  Clinical and pathological records in our hands
  
  Mutation analysis, we got it covered
  KIT, PDGFRA, NF1, and MMR, discovered
  Somatic and peripheral blood DNA in sight
  Searching for answers, shining the light
  
  GISTs linked to other malignancies, it's quite a show
  46 out of 141, let that number flow
  Gastrointestinal and genitourinary, they prevail
  These neoplasms, they never fail
  
  In the NF1/GIST kindred, a surprise was found
  A new exon 6 germline large deletion, profound
  NF1 stepping up, making its presence known
  In the midst of this GIST Syndrome zone
  
  When GISTs show up with other neoplasms in view
  Think familial cancer susceptibility, it's true
  Especially when neurofibroma or lung chordoma arise
  In C-KIT and PDGFRA negative GIST guys
  
  So keep an eye out, be aware, take heed
  Familial or syndromic settings, that's the lead
  When it comes to GIST and its associated crew
  Stay vigilant, 'cause there's more than meets the view