text: Yo, listen up, I got a tale to tell,
  'Bout Darmstoff and its chemical spell.
  Family of acids that stimulate the gut,
  Smooth muscle action, you know what's up.
  
  Isolated and characterized back in the day,
  From the bath fluid, they found their way.
  Structurally and biologically akin,
  But as LPA mimetics, they haven't been seen.
  
  But hold up, I got news to share,
  A method to synthesize, it's gonna be rare.
  Potassium salts of Darmstoff analogs on the scene,
  Ready to rock, you know what I mean?
  
  Stereochemistry, let's dive deep,
  Optically pure isomers, a secret to keep.
  Starting with chiral methyl glycerates,
  We're gonna see how they resonate.
  
  LPA receptor activity, we gonna test,
  Agonist or antagonist, which is best?
  PPARgamma activation, let's see what it brings,
  And autotaxin inhibition, the real deal it sings.
  
  Compound 12, a pan-antagonist we found,
  And pan-agonists too, all around.
  LPA receptors one to three,
  They're gonna feel the analogs' spree.
  
  Analog 22, with an aromatic ring,
  LPA(3) agonist, let it sing.
  EC(50) at 692 nM,
  Subtype-specific, it's a gem.
  
  But wait, there's more, don't you know?
  All the Darmstoff analogs make PPARgamma glow.
  Activators they are, through and through,
  But weak inhibitors of autotaxin, it's true.
  
  So there you have it, a novel crew,
  Darmstoff analogs, LPA mimetics anew.
  They're making waves, breaking the mold,
  In the world of science, a story to be told.