text: Yo, listen up, I got a tale to tell,
  'Bout colon carcinogenesis, where it all dwells.
  It's a stepwise progression, from polyps benign,
  To invasive adenocarcinomas, a dangerous sign.
  
  Protein-coding proto-oncogenes, they're the ones to blame,
  When they're activated or inactivated, it's not a game.
  Tumor suppressor genes, they're in the mix too,
  Aberrant activation, causing trouble through and through.
  
  But hold up, there's more, let me give you the scoop,
  MicroRNA research, it's changin' the group.
  Non-protein-coding genes, they got a role to play,
  In the world of carcinogenesis, they make their way.
  
  In colon cancer tissues, miRNAs go wild,
  Differential expression, they're not mild.
  They mess with cell proliferation, apoptosis, and more,
  Interacting with signaling networks, that's for sure.
  
  From a clinical standpoint, miRNA's got a say,
  Polymorphisms in binding sites, they show the way.
  Colon cancer risk, it's associated right there,
  And miRNAs in feces or blood, they're biomarkers we share.
  
  MiRNA expression, polymorphisms too,
  They correlate with survival, treatment outcome, it's true.
  Patient's fate is influenced by these genes,
  They hold the key to understanding what it all means.
  
  So keep an eye out, we're on the brink,
  MiRNA dysregulation, that's what we think.
  With advancements in RNA delivery tech,
  MiRNA-based therapeutics, the future, what the heck!
  
  We're gonna fight colon cancer with all our might,
  Using miRNA knowledge, shining so bright.
  So remember this story, let it be heard,
  MiRNAs and colon cancer, a tale that's preferred.