text: Yo, check it out, listen up, I'm 'bout to drop some knowledge,
  Talking 'bout thiopeptide antibiotics, they got the power to demolish,
  Targeting that translational machinery, they ain't playin' around,
  Thiostrepton and nosiheptide, they shut the ribosome down.
  
  Inhibit translation factor function, that's their game,
  While GE2270A/T goes for EF-Tu, it ain't the same,
  Preventing ternary complex formation, that's the deal,
  These antibiotics got skills, they keep it real.
  
  We took it to the lab, ran some in vitro assays,
  Screened a library of thiopeptide precursor compounds, no delays,
  And guess what? We found four families that stand out,
  Inhibitory compounds and some that relieve the doubt.
  
  ThS, NoS, and GE2270T, they met their match,
  These precursor compounds know how to snatch,
  Some bind to ribosomes, they got their own style,
  These results give us insight, it's all worthwhile.
  
  Thiopeptide compounds, we understand 'em better now,
  And these assays, they put us on the right track, wow,
  Finding lead compounds that others might have missed,
  This research, it's revolutionary, can't resist.
  
  So remember, it's not just about inhibitory screening alone,
  These assays got potential, they've shown,
  To uncover compounds that got that special touch,
  Thiopeptide antibiotics, they're packin' much.