text: Yo, check it out, let me break it down for you
  We studied the impact of changes, yo, in sterols and phospholipids too
  On the rate of interaction between polyene antibiotics and sterols, it's true
  Filipin and amphotericin B, they both had a preference, yo, it's what they do
  
  They interacted more with sterols, yo, whose side chains were close to cholesterol
  If you introduce trans double bonds, yo, the rate of interaction still remains neutral
  That delta 7-bond in the sterol, it's crucial for amphotericin B's game
  But that delta 5-bond, yo, it ain't essential, it's kinda lame
  
  These findings, yo, they connect to the effects we know
  How amphotericin B messes with membranes, yo, it's quite a show
  Ergosterol, cholesterol, different effects, yo, they display
  Depending on the cell membrane, yo, where these antibiotics play
  
  Now when it comes to the rate of interaction, yo, phospholipids play a role
  In vesicles, yo, they can't give us the full story, they ain't whole
  These models, yo, they fall short in understanding the agents at hand
  To truly grasp their effects on biological membranes, yo, we need a better plan