text: Yo yo yo, listen up y'all
  MicroRNA-101, also known as miR-101
  Down-regulated in hepatocellular carcinoma, that's HCC
  HBV, hepatitis B virus, a major risk factor, can't you see?
  
  But the correlation between HBV and miR-101
  Hasn't been fully elucidated, it's not yet done
  In this study, we found HBV can repress miR-101-3p
  By inhibiting its promoter activity, that's what we see
  
  We identified the potential effects of miR-101-3p
  On some important biological properties of HCC cells, you see
  By targeting Rap1b, a protein that's key
  Dual-luciferase reporter assays showed HBV down-regulated miR-101-3p
  
  Down-regulation of miR-101-3p promoted cell proliferation and migration
  Reduced apoptosis, up-regulation of Rap1b, it wasn't a good indication
  Overexpression of miR-101-3p inhibited these processes
  It's true, it's true, we confess
  
  Plus, overexpression of Rap1b could reverse
  The suppressed cell proliferation and migration, that's no curse
  Our data showed HBV down-regulated miR-101-3p expression
  By inhibiting its promoter activity, leading to up-regulation of Rap1b, that's the connection
  
  Down-regulation of miR-101-3p or up-regulation of Rap1b
  Promoted proliferation and migration of HCC cells, that's not fab
  This study provides new understanding of HBV-related HCC pathogenesis
  And the potential application of miR-101-3p in cancer therapy, that's the genesis.