text: Yo, check it out, here's the lowdown
  Talkin' 'bout HPV-independent Vulvar Squamous Cell Carcinomas, hold your crown
  These cancers and their precursors, they got a mutation, TP53 in the mix
  Six patterns of p53 immunohistochemical, that's the new fix
  
  But listen up, not many studies been done, they lackin' comparison
  Between invasive VSCC and adjacent skin, that's the situation
  So we stepped up, performed p53 IHC on 779 HPV-independent VSCC
  With adjacent skin, we evaluated, put the slides to the test, you see
  
  74.1% of invasive VSCC had abnormal p53 IHC stainin'
  Skin lesions found in 450 cases, that's what we're explainin'
  Among 'em, we got 254 intraepithelial precursors, and 196 inflammatory/reactive lesions
  We checked 'em out, compared the p53 IHC, made some observations
  
  In 47% of VSCC with associated skin lesions, p53 IHC was abnormal, no doubt
  And in 80% of those cases, the staining pattern matched, that's what it's about
  Now, 32% of VSCC, a wild-type p53 IHC was seen
  Both in the invasive VSCC and adjacent skin lesion, clean
  
  Then we got 21% of VSCC, abnormal p53 IHC in the invasive VSCC, let me explain
  But a wild-type p53 staining in the skin lesion, that's the game
  Most of these cases, about 73%, had adjacent inflammatory lesions nearby
  That's how it goes, the p53 IHC staining can make you wonder why
  
  To wrap it up, let me give you the final word
  The p53 IHC staining and pattern, they mostly match, it's absurd
  In VSCC and the intraepithelial precursor, you'll find the same
  That's the conclusion, from this study's claim