text: Yo, check it out, listen to the science I'm droppin'
  Studies showin' genetic activation, no stoppin'
  TFIIB-related factor 2, BRF2's the name
  Tumorigenesis mechanism, it's bringin' the fame
  
  Pol III-mediated transcription on the rise
  BRF2 overexpressed, no surprise
  Cancer types affected, it's got 'em all
  BRF2 playin' the oncogenic role
  
  Esophageal squamous cell cancer, that's the focus
  We studyin' BRF2 expression, prognosis
  Clinicopathologic factors, tumor angiogenesis too
  We diggin' deep, seein' what BRF2 can do
  
  BRF2 protein expression, it's on the rise
  Deeper tumor invasion, yeah, that's no lies
  Microvessel density, it's also correlated
  BRF2's impact, we just calculated
  
  Prognostic factor, BRF2 stands alone
  In ESCC patients, its significance shown
  High expression, shorter survival time we see
  In different subgroups, it's the harsh reality
  
  Clinical stage, T classification, lymph node spread
  High BRF2 expression, it fills us with dread
  Tumor progression, angiogenesis in the mix
  Survival rates droppin', it's a risky fix
  
  BRF2, a biomarker with potential, no doubt
  Identifyin' poor prognosis, we shout it out
  Prognostic marker for ESCC patients, we conclude
  BRF2's the key, prognosis improved