text: Yo, check it out, here's the deal
  We got three groups of rats, let me reveal
  Ovariectomized, ready for the test
  Treated for six days, let's see who's the best
  
  Group one, they got that estradiol benzoate
  Injected in the skin, feeling great
  They ate all they wanted, no limit or restraint
  Hoping to see some changes, something to gain
  
  Group two, the control, just the same
  Injected with vehicle, playing the game
  They ate the same amount, no need for stress
  Comparing to group one, who's gonna impress?
  
  Group three, they're free-feeding, no injection
  Eating as they please, no restriction
  Now let's measure the insulin, see what we find
  In the liver and hypothalamus, it's all in our mind
  
  Using film autoradiography, we'll quantify
  The specific binding of insulin, oh my
  Estradiol-treated rats lost weight, that's a fact (p < 0.001)
  Their plasma insulin levels were on the attack (p < 0.01)
  
  Liver insulin binding, let's dive deep
  In estradiol-treated rats, it's a secret to keep
  Greater than the ones without estradiol, no doubt (p < 0.01)
  But less than the controls, that's what it's about (p < 0.05)
  
  So with the same food intake, estradiol does its thing
  Decreasing liver insulin binding, no bling
  Now let's talk about the hypothalamus, my friend
  The dorsomedial, ventromedial, and arcuate, let's comprehend
  
  Food intake and estradiol, they didn't make a change
  Insulin binding in those nuclei, it's all in range
  So it seems the effects of insulin and estradiol
  On food intake, it's a different goal
  
  The arcuate, ventromedial, and dorsomedial, they're not involved
  In the insulin or estradiol mysteries that revolved
  Food intake, it's a complex affair
  But now we know a bit more, so let's take care