text: Yo, check it out, I'm 'bout to rap this passage real quick,
  Keepin' the content untouched, no need to tweak or fix.
  Let me break it down for you, scientific style,
  Talkin' 'bout heme oxygenase, let me bring the hype.
  
  Heme breakdown, that's the name of the game,
  HO enzymes catalyze it, they got the fame.
  Neurons and astrocytes, they vulnerable to hemoglobin,
  But without HO-2, things start to go missin'.
  
  This study here, it's all about the effect,
  Of HO-1, the inducible isoform, you can't neglect.
  Wild-type astrocytes, treated with hemoglobin,
  No loss of viability, that's how they be livin'.
  
  LDH and MTT assays, they quantified the deal,
  No cell death, astrocytes keepin' it real.
  But them HO-1 knockout cells, they takin' a hit,
  25 to 50 percent dyin', protein oxidation legit.
  
  HO-1 gene transfer, that's the savior in sight,
  Protectin' astrocytes, bringin' back the light.
  Bilirubin ain't the answer, it can't do the trick,
  Antioxidant heme breakdown, but it ain't that slick.
  
  Now let's talk neurons, they in a different zone,
  Protein oxidation and cell death, they hold their own.
  Wild-type or HO-1 knockout, don't matter much,
  Hemoglobin exposure, they both feel the clutch.
  
  So there you have it, the rap version straight,
  HO-1 induction, it's astrocytes it elevates.
  But neurons, they ain't affected, stayin' steady,
  This study's conclusion, now it's all ready.