text: Yo, check it out, I'ma drop some knowledge on ya
  'Bout reactive oxygen and nitrogen species, no drama
  Superoxide and nitric oxide, they come into play
  Under different conditions, causing signaling in their own way
  
  NO induces apoptosis, necrosis in mesangial cells
  But it protects hepatocytes, man, that story tells
  NO and O(2)(-) together, they interact
  Changing the signaling properties, that's a fact
  
  In mesangial cells, O(2)(-) formation does attenuate
  NO-initiated apoptosis, now ain't that great?
  But the mechanisms ain't clear, we gotta investigate
  The impact of the glutathione redox system, mate
  
  Comparing mesangial cells to Hep G2 hepatocytes
  NO donors ain't affecting Hep G2, no worries
  But when NO and O(2)(-) combine, it's a disaster
  Massive cell destruction, that's the aftermath, bruh
  
  GSSG levels shoot up in Hep G2, it's insane
  More than mesangial cells, they feel the pain
  Depleting GSH reverses protection in mesangial cells
  Enhances cell damage in Hep G2, man, that's swell
  
  Mesangial protection tied to glutathione reductase activity
  And an increase in GSH, that's the key
  To wrap it up, NO/O(2)(-) sensitivity ain't the same
  It's cell type specific, linked to the glutathione redox game