text: Yo, check it out, listen up, here's the deal
  I'm spittin' facts 'bout mice, so let me make it real
  C57BL/6 and C57BL/10, strains inbred
  These mice can't develop IgE, that's what I said
  
  Ragweed pollen extract, known as RE
  And its dinitrophenylated derivative, DNP-RE
  These substances won't trigger a response, you see
  Genetically, these mice can't make IgE antibodies
  
  It was thought before, Ir genes were to blame
  Controlling the responses, that's the game
  But hold up, there's more to the story, fam
  Low doses of X radiation or cyclophosphamide, damn!
  
  These treatments change the game, they break the mold
  H-2b mice become responders, bold
  Suppressive mechanisms get removed, no doubt
  Inhibiting IgE development, that's what it's about
  
  These findings got implications, let's comprehend
  Genetic control of IgE, it's a trend
  The Ir-gene concept, we gotta discuss
  How it all ties together, so let's make a fuss