text: Yo, check it out, I'm 'bout to drop some knowledge,
  Talkin' 'bout nicorandil and how it affects the college,
  Of intracellular Ca(2+), that's calcium inside,
  Endothelial cells in the rat caudal artery, let's ride.
  
  With fluorescent confocal imaging, we got it all in sight,
  HPLC with fluorescent detection, keepin' it tight,
  Nicorandil stepped up, increased that [Ca(2+)](i) level,
  Overflowed ATP and its metabolites, a rebel.
  
  No extracellular Ca(2+), the reaction was null,
  But with thapsigargin or cyclopiazonic acid, it was still full,
  Glibenclamide, the ATP-sensitive K(+) channel blocker,
  Suppressed the increase, like a lyrical shocker.
  
  Nicorandil activated the channels, that's the key,
  Ca(2+) influx in endothelial cells, can't you see?
  The higher [Ca(2+)](i), the lower the intracellular ATP,
  It's a correlation, a connection, can't you agree?
  
  ATP release linked to the increase, that's the deal,
  Nicorandil, the opener, got that power to reveal,
  So remember this rap, let it stick in your brain,
  Nicorandil and its effects, droppin' knowledge like rain.