text: Yo, listen up, I got some knowledge to drop,
  'Bout Prader-Willi syndrome and Angelman syndrome, non-stop.
  These neurogenetic disorders got a distinct flow,
  When genes in the 15q11-q13 region don't show.
  
  The SNRPN gene, it's messed up in PWS,
  And it's the key player in the imprinting game, no less.
  To understand how this gene's expression goes,
  We developed single-cell methods, you know.
  
  We checked out human oocytes, right from the start,
  And all stages of preimplantation, playing our part.
  SNRPN transcripts were found, loud and clear,
  This gene's active, no matter the time of year.
  
  Using embryos with a polymorphism in this gene,
  We saw monoallelic expression, it was quite the scene.
  By the 4-cell stage, the paternal allele takes control,
  Imprinting epigenetic info, already in the embryo's soul.
  
  Now, here's the real deal, it's something you gotta see,
  PWS diagnosis in the preimplantation, that's the key.
  Just analyze the presence or absence of SNRPN mRNA,
  And you'll know if PWS is there, no delay.
  
  So, that's the rap on PWS and AS, my friend,
  Imprinted genes and their role, till the end.
  Now you got the knowledge, it's time to blaze,
  Spread the word about these disorders in so many ways.