text: Yo, listen up, I got a story to tell,
  'Bout some rats in chambers, where they dwell.
  Sprague-Dawley males, they were the crew,
  Exposed to halothane and enflurane, it's true.
  
  Concentrations ranged from 50 to 1000 parts per mil,
  That's 0.0025 MAC to 0.05 MAC, chill.
  Six hours a day, for three to eleven days straight,
  But toxicity signs? Nah, they couldn't relate.
  
  Weight increase was normal, food consumption too,
  Organ to body weight ratios, all good, no issue.
  Liver, kidney, and lung, histology was fine,
  No abnormalities in sight, everything in line.
  
  At 500 parts per mil, halothane made a move,
  Activated NADPH-cytochrome-c-reductase, it proved.
  Kidney's cytochrome P-450 levels took a fall,
  And lung microsomes, all enzyme concentrations small.
  
  But at 50 parts per mil, halothane and enflurane,
  Just caused minor changes, nothing insane.
  Conclusion? Halothane's inhalation might mess,
  With drug metabolism, kinetics, causing distress.
  
  NADPH-cytochrome-c-reductase got hyped in the liver,
  Halothane's own toxicity, it did deliver.
  Different organs showed different enzyme reactions,
  That's the deal with these inhalation interactions.