Datasets:
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README.md
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---
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license: apache-2.0
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tags:
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- biology
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- dna
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- reasoning
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---
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# Variant Effect Coding Non-SNVs Dataset
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36,088 core non-SNV entries from ClinVar 2024-02-28 release, filtered for coding variants with ≥2-star review status, using stratified train/test splits for balanced disease representation in pathogenic/benign classification.
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## Usage
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```python
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from datasets import load_dataset
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dataset = load_dataset("wanglab/variant_effect_non_snv")
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example = dataset["train"][0]
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print(example)
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```
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## Citation
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```
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@misc{fallahpour2025bioreasonincentivizingmultimodalbiological,
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title={BioReason: Incentivizing Multimodal Biological Reasoning within a DNA-LLM Model},
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author={Adibvafa Fallahpour and Andrew Magnuson and Purav Gupta and Shihao Ma and Jack Naimer and Arnav Shah and Haonan Duan and Omar Ibrahim and Hani Goodarzi and Chris J. Maddison and Bo Wang},
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year={2025},
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eprint={2505.23579},
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archivePrefix={arXiv},
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primaryClass={cs.LG},
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url={https://arxiv.org/abs/2505.23579},
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}
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```
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