5df75927_r_Batch_7___Environment_Canada__Response
[Comment] There is some confusion as to whether there are any developmental or neurological effects from exposure to isophorone. [Response] 
A critical evaluation of available studies did not identify developmental endpoints as critical effects for characterization of risk to human health. The large margin of exposure to the effect level from animal studies used to characterize risk to human health is protective of potential neurological effects.
Summary of Public Comments received on the Challenge substance Isophorone (CAS 78-59-1) Draft Screening Assessment Report for Batch 7 - Environment Canada
Response