8fb70e90_Transfusion_Reaction__Pathophysiology
[Reaction] Transfusion-associated graft-vs.-host disease (GVHD) [Symptom Description] GVHD refers to an immune attack by transfused cells against the recipient. This is a common complication of stem cell GVHD refers to an immune attack bytransfused cells against the recipient. This is acommon complication of stem cell transplantation, but an exceedingly rare complication of blood transfusion. It can occur in immunosuppressed patients, primarily those with congenital immune deficiencies or intensive chemotherapy. When GVHD occurs in association with blood transfusion, it is almost uniformly fatal. [Pathophysiology] 
Transfusion-associated GVHD can be prevented by irradiating the blood products prior to transfusion.
Transfusion Reaction
Pathophysiology