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[Agency] AHRQ [Project Title] RESCUE: Randomized Evaluation of Patients with Stable Angina Comparing Utilization [Institution] American College of Radiology [Amount] $0 [Summary] RESCUE is a multi-center randomized, controlled trial comparing coronary CT angiography (CCTA) and single photon emission tomography myocardial perfusion imaging (SPECT-MPI) integrated into a stable angina care paradigm featuring optimized medical therapy for patients diagnosed with CAD without significant disease in the left main coronary artery. Patients will be followed for a composite endpoint of major adverse cardiac events (MACE) and cross-over to revascularization over a 12-24 month period. Several comparative effectiveness analyses will be performed. The investigators hypothesize that the CCTA arm will be associated with no increase in major coronary events (MACE) or revascularization, decreased cost and increased cost-effectiveness in comparison to SPECT-MPI. Findings are expected to result in validation of an evolving new standard of care for patients with stable angina that takes advantage of CCTA to more cost effectively drive appropriate care. [Completion/ Closing Date] 10/02/2010 [Link] link [Category] 
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