e38594b2__Your_Online_Lab_Test_Resource__Recommended_Use
[Test Name and Number] Non-Invasive Prenatal Testing for RhD Genotyping, Fetal 2009077 Method: Mass Spectrometry [Limitations] Mother must be at least 10 weeks pregnant and have Rh negative blood type Test is specific for RHD gene – other causes of alloimmune hemolytic disease will not be detected Rare mutations (eg, missense, nonsense, insertions, gene fusion, or small deletions) will not be detected In these cases, the sample may test as RHD-positive and be misinterpreted as RhD-positive (false-positive) [Recommended Use] 
Use to determine fetal RHD and fetal gender RHD genotyping is appropriate only when the mother is Rh negative and the father is heterozygous for RHD or not available for testing Useful after 10 weeks gestation Clinical sensitivity – 98% Analytic sensitivity – 99% Analytic specificity – 98.3%
Hemolytic Disease of the Newborn - ARUP Consult, Your Online Lab Test Resource
Recommended Use