db47c863__Conventional_Drugs___EthnoMed__Drugs_Affected
[Herb/Spice] Khat Catha edulis Chat (A) Ciut (T) (O) [Common Uses] Mostly recreational Medicinal: stimulant, mental illness, gonorrhea, common cold [Mechanism] Cathinone (active ingredient) may act synergistically with amphetamines Tannins (component of Khat) complexes with ß-lactam antibiotics [Consequences] Possible additive effect with amphetamines Decreases absorbability of b-lactam antibiotics Lowers seizure threshold, Increases b.p and heart rate and induces cardiac arrythmias. [Drugs Affected] 
Amphetamines Amoxicillin and ampicillin, PCN others
Ethiopian Traditional and Herbal Medications and their Interactions with Conventional Drugs — EthnoMed
Drugs Affected