46887615_2_Diabetes_Therapy_if_Approved__5
[0] Biguanides [1] Metformin [2] Inhibition of gluconeogenesis, the mechanism of glucose production in cells, especially in the liver [3] Inexpensive, usually well tolerated, serious side effects uncommon, weight neutral [4] Contraindicated if renal insufficiency, rare lactic acidosis, fairly common GI side effects [5] 
First choice drug for type 2 diabetes if no renal insufficiency
Where Will Invokana (canagliflozin) Fit in Type 2 Diabetes Therapy if Approved
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