e10510d2__Information___Medicine_Online_odifications_for_Skin_Toxicity_Suggested_Dose_Modification
[Occurrence] No improvement within 7 days or 2nd or 3rd occurrence [Suggested Dose Modification] 
Interrupt NEXAVAR treatment until toxicity resolves to Grade 0-1 When resuming treatment, decrease NEXAVAR dose by one dose level (400 mg daily or 400 mg every other day)
NEXAVAR(sorafenib)tablets 200 mg Drug Information - Medicine Online
Suggested Dose Modification