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[Agency] NIH [Project Title] COMPARATIVE EFFECTIVENESS & MEDICAL INTERVENTIONS FOR PRIMARY OPEN ANGLE GLAUCOMA [Institution] JOHNS HOPKINS UNIVERSITY [Amount] $454,142 [Summary] Propose to assess the comparative effectiveness of multiple medical interventions available for primary open angle glaucoma (POAG) using the state-of-art Bayesian MTC meta-analysis models. POAG poses substantial burdens on patients and health care resources. Utilizing data from existing high quality randomized controlled trials, we will perform MTC meta-analysis and rank multiple medical treatment options for POAG. We will validate the MTC meta-analysis models and assess the impact of publication bias. We will report and disseminate our findings on the comparative effectiveness of medical interventions for POAG, as well as utility and validity of MTC meta-analysis techniques for comparative effectiveness research. [Completion/ Closing Date] 10/01/2010 [Link] link [Category] 
Medical treatments, items and services
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