b8b20101_mor_lysis_syndrome_and_in_gout__sburicase__an_uricolytic_agent
It increases precursors of uric acid, such as xanthine, less soluble in urine than uric acid. It may impair renal function and improve stone formation.
It does not require alkalinization, so calcium phosphate's stones formation is less probable.
Rasburicase represents a new tool for hyperuricemia in tumor lysis syndrome and in gout
Rasburicase: an uricolytic agent