8b85b910_d_s_Flow___Scientific_American__2
[0] ACE inhibitors [1] Perindopril, Captopril [3] Older generation ACE inhibitors can cross the blood-brain barrier and may stave off cognitive decline in people with Alzheimer’s. Some evidence suggests that the drugs might slow the buildup of harmful proteins in the brain. Newer types of ACE inhibitors, however, don’t cross the barrier, and they have been found to have the opposite effect: they might increase the risk of developing dementia. [2] 
ACE inhibitors lower blood pressure by suppressing the action of an enzyme that encourages blood vessels to constrict.
Common Prescription Drugs Alter Blood’s Flow - Scientific American
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