4a6317d1_Afrezza__July_2010__Comment
[#] 4 [Response from NICE-UK] The Committee discussed the evidence on quality of life with injected and inhaled insulin in detail. [Comment] 
This appraisal clearly ignores the discomfort - often pain - together with the embarrassment of injecting, for example, on an aircraft (Difficult anyway!) or other public place - indeed, even in meetings at work. Injections often go less than satisfactorily; e.g.: the insulin may not disperse quickly enough at the chosen site, resulting in a painful lump until it disperses; one may inject through a nerve or blood vessel. In the latter case, the bleeding after withdrawal of the needle often causes insulin to be expelled with the blood, so the dose is inaccurate. I inject twice per day. However, I am likely to need to inject more than this before long, probably 4 times per day. Some people need to inject 6 times per day. Surely the benefit of not having to inject so often, and using an inhaler instead, would be worthwhile? I am trying hard to avoid going onto more frequent injections, so my HbA1c figure is too high, and inevitably I will suffer problems later on - and those problems will cost me quality of life, and the NHS a lot more money. Also, I will probably die sooner; but I guess that would be welcome to the NHS in terms of reduced cost.
Afrezza: July 2010
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