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[Agency] NIH [Project Title] CONSERVATIVE VERSUS DIALYTIC MANAGEMENT IN STAGE V CHRONIC KIDNEY DISEASE [Institution] STANFORD UNIVERSITY [Amount] $478,672 [Summary] Patients with advanced chronic kidney disease (CKD) may or may not benefit from the initiation of dialysis in the absence of symptomatic uremia (accumulation of the bloodstream with by- products of metabolism). This pilot clinical trial aims to determine the feasibility, safety and efficacy of two alternative strategies - one in which patients with advanced CKD begin dialysis, and another in which a series of conservative measures are instituted and dialysis is deferred until there is further loss of kidney function. If this pilot trial demonstrates feasibility in randomizing patients to these two strategies, results from this pilot study can be used to inform the design of a larger, more definitive trial. [Completion/ Closing Date] 08/02/2010 [Link] link [Category] 
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