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[Agency] NIH [Project Title] COST-EFFECTIVENESS OF HORMONAL THERAPY FOR CLINICALLY LOCALIZED PROSTATE CANCER [Institution] KAISER FOUNDATION RESEARCH INSTITUTE [Amount] $499,957 [Summary] Propose a new comparative effectiveness study to provide information on the risks and potential benefits of immediate ADT in men diagnosed with localized prostate cancer. Our three aims include estimating the comparative effectiveness of immediate ADT versus observation in terms of all cause and prostate-cancer specific mortality and progression-free survival, estimating the longitudinal direct medical care costs to capture the impact of ADT, and calculating the cost- effectiveness (cost per life years saved) and cost-utility (quality-adjusted life years) using published patient utilities for multiple prostate cancer health states. [Completion/ Closing Date] 09/02/2010 [Link] link [Category] 
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