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[Agency] NIH [Project Title] SEVERITY SCALE AND QUALITY OF LIFE INSTRUMENT FOR INFANTILE HEMANGIOMAS [Institution] Indiana University-Purdue University at Indianapolis [Amount] $268,981 [Summary] This application addresses broad Challenge Area (05) Comparative Effectiveness Research and specific Challenge Topic, 05-AR-102: Comparative Effectiveness (CE) of Treatments for Chronic Childhood Arthritis and Musculoskeletal (MSK) and Skin Disease. Infantile hemangiomas (IH) are the most common tumor of infancy, occurring in 1-5% of the children, yet no FDA approved treatments exist. The primary objective of this proposal is to develop a research platform to develop (1) standardized nomenclature for disease severity and (2) instruments to measure response to therapy to guide the design of studies. This objective will be achieved by first creating a research infrastructure, the Hemangioma Investigator Group Research Core (HIG-RC), to provide support in the areas of research design, implementation, and data interpretation. [Completion/ Closing Date] 09/02/2010 [Link] link [Category] 
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