e10510d2__Information___Medicine_Online_odifications_for_Skin_Toxicity_Suggested_Dose_Modification
[Skin Toxicity Grade] Grade 1: Numbness, dysesthesia, paresthesia, tingling, painless swelling, erythema or discomfort of the hands or feet which does not disrupt the patient's normal activities [Occurrence] Any occurrence [Suggested Dose Modification] 
Continue treatment with NEXAVAR and consider topical therapy for symptomatic relief
NEXAVAR(sorafenib)tablets 200 mg Drug Information - Medicine Online
Suggested Dose Modification