00a95e53_The_Winning_Weaning_Parameters__3
[0] Pressure Time Product [1] 200-300 cm H2O/sec/min [3] 
Pressure Time Product (PTP) is an estimate of metabolic work (oxygen consumption) of the respiratory muscles. This maybe used to evaluate patient effort to overcome both mechanical and isometric force of respiration. PTP decreases with the application of optimal pressure support (PSV) and continuous positive airway pressure (CPAP). PTP varies directly with total lung resistance. This variable is an important indicator of the actual patient effort to breath. Any isometric muscle contraction by the patient exerted to overcome Auto PEEP or to open the inspiratory demand system results in no tidal volume change and, therefore, accomplishes little or no measurable work. In this case, PTP may reflect the patient's muscular effort more faithfully than work of breathing. Non- intubated patients should average between 60-80 cm H2O/sec/min.
The Winning Weaning Parameters
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