e2d5a769_Fungal_Pneumonia__ication_for_Antifungal_Therapy
[Fungal Pathogen] Coccidioidomycosis Surgical debridement or resection of infective tissue often necessary adjunct to antifungal treatment Anti-inflammatory agents for rheumatologic syndromes [Antifungal Drugs Used] Amphotericin B effective in more than 90% of cases; first choice in severe cases or immunocompromised Fluconazole/itraconazole first choice in mild to moderate infection (or after improvement) Treatment less effective than in other endemic mycoses
Disseminated disease; chronic pulmonary disease; acute pulmonary infection with hypoxia or protracted morbidity (>1-2 mo); immunosuppressed host (worst outcome, 70% mortality)
Fungal Pneumonia
Indication for Antifungal Therapy