fb61bd32_Taking_Nutritional_Supplements__Reasons_for_Caution
[Clinical Problem] Peripheral Vascular Disease [Potentially Harmful Nutrient] Niacin > 100 mg/day [Reasons for Caution] 
Niacin at 1g/day increased plasma homocysteine levels by 55% in those with arterial disease. Use of other B vitamins may prevent this.
Minor Contraindications to Taking Nutritional Supplements
Reasons for Caution