332f662d_Supplements_for_Pain__effectiveness
[supplement & summary] Glucosamine. Like chondroitin sulfate, known as being “good for cartilage.” An abundant monosaccharide (amino sugar) and a building block of proteins and fats, especially in cell walls. Made commercially by extracting it from crustacean exoskeletons as a supplement used to treat osteoarthritis (especially hips and knees) via alleged anti-inflammatory and other happy effects on cartilage. [safety] probably safe at recommended doses, possible pancreatic damage with more7 [more information] Examine.com, Wikipedia, QuackWatch and the book Snake Oil Science (Bausell) [effectiveness] 
low plausibility, no good research news in general,34 and it notably bombed two particularly good new tests in 2010,56 benefits for osteoarthritis possibly real but barely clinically significant, like “taking a car from 40mpg to 42mpg” (Examine.com editor Sol Orwell)
Supplements for Pain
effectiveness