45b326c5_Chart___Joslin_Diabetes_Center__3
[0] Thiazolidinediones Pioglitazone (TZDs) Pioglitazone (Actos) [1] Usually taken once a day; take at the same time each day. [2] Makes the body more sensitive to the effects of insulin. [4] Increases the amount of glucose taken up by muscle cells and keeps the liver from overproducing glucose; may improve blood fat levels. Talk with your healthcare provider if you have the following symptoms: nausea, vomiting, fatigue, loss of appetite, shortness of breath, severe edema or dark urine. [3] 
May cause side effects such as swelling (edema) or fluid retention. Do not cause low blood sugar when used alone. Increased risk of congestive heart failure in those at risk.
Oral Diabetes Medications Chart | Joslin Diabetes Center
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