fb61bd32_Taking_Nutritional_Supplements__Reasons_for_Caution
[Clinical Problem] Medication AntimalarialsAnti-epileptics: Phenytoin, Phenobarbitone Primidone Carbamazepine Sotalol Penicillamine HRT [Potentially Harmful Nutrient] Riboflavin – vitamin B2*Vitamin B6* Folic acid Vitamin B3 – nicotinamideCalcium*Iron* Zinc* Vitamin C > 1g/day [Reasons for Caution] 
Riboflavin may alter the activity of some antimalarial drugs. Evening Primrose Oil is not always contraindicated in epileptics High doses of vitamin B6 and folic acid might rarely reduce drug effectiveness. Nicotinamide may increase the blood levels of this drug; use with caution. Minerals form an insoluble complex with Sotalol. Separate them by at least 4 hrs. The absorption of penicillamine can be reduced by these minerals. May increase the level of oestrogen and possibly effects/side-effects
Minor Contraindications to Taking Nutritional Supplements
Reasons for Caution