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[Agency] NIH [Project Title] PREVENTING SPIKE-WAVE EPILEPTOGENESIS: CRITICAL PERIODS & NEUROIMAGING BIOMARKERS [Institution] YALE UNIVERSITY [Amount] $408,183 [Summary] The aims are to investigate fMRI resting functional connectivity and DTI as promising biomarker of epileptogenesis and its prevention by therapy. Will performing measurements of fMRI resting functional connectivity at different developmental stages in treated vs. untreated animals. We will also relate these measurements to connectivity evaluated through coherence analysis of electroencephalography. In addition, we will investigate DTI as another promising biomarker by again performing measurements at different ages in treated vs. untreated animals. [Completion/ Closing Date] 09/02/2010 [Link] link [Category] 
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