99957ebf_us_Bulletin___October_16__2013__Research_Summary
[PI / Co-PIs] Jeannie Padowski/ Jonathan Wisor [Department(s)] College of Pharmacy/ WWAMI Spokane Cerebral Slow Wave Activity Predicts Brain Lactate Dynamics: an Electroencephalographic/Magnetic Resonance Spectroscopy Study in Humans WSU Office of Research Â Â Â [Research Summary] 
This is faculty seed grant funding for a study that will demonstrate the feasibility of simultaneous electroencephalographic (EEG) and cerebral metabolic measurements in sleeping human subjects. The current study will test the hypothesis that slow oscillations detected in the electroencephalogram of human subjects during sleep-deprived wakefulness predict a decline in lactate concentration in the cerebral cortex and that this decrease happens at the time of sleep onset. Â The long-term goal is to identify the neurobiological underpinnings of the relationship between disrupted sleep and compromised daytime function, both of which are symptoms observed in those suffering from insomnia, idiopathic hypersomnia, and traumatic brain injury.
WSU Spokane: WSU Spokane Campus Bulletin - October 16, 2013
Research Summary