5df75927_r_Batch_7___Environment_Canada__Response
[Comment] Some animal studies found some harmful health effects in adult female animals and in their offspring following isophorone exposure, while the screening assessment indicated that isophorone is not considered to be a developmental or reproductive toxicant. [Response] 
A critical evaluation of available studies did not identify developmental or reproductive endpoints as critical effects for characterization of risk to human health.
Summary of Public Comments received on the Challenge substance Isophorone (CAS 78-59-1) Draft Screening Assessment Report for Batch 7 - Environment Canada
Response