8fb70e90_Transfusion_Reaction__Pathophysiology
[Reaction] Anaphylactic reaction [Symptom Description] Anaphylactic and anaphylactoid reactions have signs of cardiovascular instability including hypotension, tachycardia, loss of consciousness, cardiac arrhythmia, shock and cardiac arrest. Sometimes respiratory involvement with dyspnoea and stridor are prominent. An anaphylactic reaction is a medical emergency, requiring prompt treatment, and may be life-threatening. [Pathophysiology] 
These reactions are most common in people with selective IgA deficiency (although IgA deficiency is often asymptomatic, and people may not know they have it until an anaphylactic reaction occurs)
Transfusion Reaction
Pathophysiology