b5fcc3bc_or_not_to_ionize____ablconnect__2
[0] 10 minutes [1] Predict ionization status of a drug with ionizable groups in stomach versus small intestine Relate ionization status to a health endpoint: permeability of membrane to ionizable drugs under variable pH conditions [3] It may be helpful to have students identify the ionizable group on aspirin. Some have difficulty identifying ionizable functional groups, initially. [2] 
Using aspirin as an example, have students determine whether the drug is charged or uncharged in the stomach and small intestine Ask students to consider the characteristics of the cell membrane and determine absorption in the two compartments
Shakespeare on Acid: To ionize or not to ionize? | ablconnect
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