82d16073___Great_Ormond_Street_Hospital__Etiology
[Event] CVC tip displacement from SVC [Can occur with] IVAP, tunneled CVC, PICC Loss of blood return, erythema in neck (if CVC in IJV) Discomfort in chest about CVC or tip with infusion of irritants or vesicants [Etiology] 
Unknown, possible increased risk with severe coughing
Extravasation and infiltration | Great Ormond Street Hospital
Etiology