4.3 Criteria for Including Substances and Methods  on the Prohibited ListWADA  shall consider the following criteria in deciding whether to include a substance or method on the Prohibited List:4.3.1 A substance or method shall be considered for inclusion on the Prohibited List if WADA , in its sole discretion, determines that the substance or method meets any two of the following three criteria:World Anti-Doping Code 20211   PARTDoping Control344.3.1.1 Medical or other scientific evidence, pharmacological effect or experience that the substance or method, alone or in combination with other substances or methods, has the potential to enhance or enhances sport performance;274.3.1.2 Medical or other scientific evidence, pharmacological effect or experience that the Use of the substance or method represents an actual or potential health risk to the Athlete;4.3.1.3 WADA ’s determination that the Use of the substance or method violates the spirit of sport described in the introduction to the Code.4.3.2 A substance or method shall also be included on the Prohibited List if WADA  determines there is medical or other scientific evidence, pharmacological effect or experience that the substance or method has the potential to mask the Use of other Prohibited Substances or Prohibited Methods.284.3.3 WADA ’s determination of the Prohibited Substances and Prohibited Methods that will be included on the Prohibited List, the classification of substances into categories on the Prohibited List, the classification of a substance as prohibited at all times or In-Competition only, the classification of a substance or method 27 [Comment to Article 4.3.1.1: This Article anticipates that there may be substances that, when used alone, are not prohibited but which will be prohibited if used in combination with certain other substances.