- Existence of approved Therapeutic Use Exemption  (TUE) When there is a Presumptive Adverse Analytical Finding  for hCG, hGH (Biomarkers Test), Beta -2 Agonists, Diuretics, Amfetamine, Methylphenidate, Glucocorticoids or Beta -blockers , the Laboratory  may contact the Testing  Authority  (or Results Management  Authority , if different) to enquire whether an approved Therapeut ic Use Exemption  (TUE) exists for the Prohibited Substance(s)  detected.