FIL 2021 Anti -Doping Rules  Page 13 of 64    4.4.1   The presence of a Prohibited Substance  or its Metabolites  or Markers , and/or the Use or Attempted Use , Possession  or Administration  or Attempted Administration  of a Prohibited Substance  or Prohibited Method , shall not be considered an anti -doping rule viol ation if it is consistent with the provisions of a TUE granted in accordance with the International Standard  for Therapeutic Use Exemptions .