8.1.1  When assessing a newly matched Sample  in a Passport :  • The APMU  shall assess the validity of individual Samples  contained within the Passport  in ADAMS and address any observed irregularities according to Article 8.2 of this TD  by updating the APMU Report ; • The APMU  shall review any new Samples  within the updated Passport  and provide Target Testing, Sample analysis or other recommendations via the APMU Report  as required;  • Where required for its analysis, the APMU  may request further information from the Passport Custodian including, but not limi ted to, circumstances and details of Sample collection, transport, and analysis, redacted Athlete Competition  schedule, travel history, Athlete performance, redacted Athlete  medical information, information on an Adverse Analytical Finding (AAF)  that is po tentially relevant in the context of the Passport , or altitude/whereabouts information which may help them interpret the new Sample;  • Where the Passport  includes elements justifying a review or upon request by the Passport Custodian, the APMU  shall send the Passport  for review in ADAMS by an Expert .