4.4  Therapeutic Use Exemptions (“ TUEs ”)   4.4.1   The presence of a Prohibited Substance  or its Metabolites  or Markers , and/or the Use or Attempted Use, Possession  or Administration  or Attempted Administration of a Prohibited Substance or Prohibited Method, shall not be considered an anti -doping rule viol ation if it is consistent with the provisions of a TUE granted in accordance with the International Standard for Therapeutic Use Exemptions .