An Athlete  may apply retroactively for a TUE (but must still meet the conditions in Article 4.2)  if any one of the following exceptions appl ies:    a) Emergency or urgent treatment of a medical condition was  necessary;   b) There was insufficient t ime, opportunity or other exceptional circumstances that prevented the Athlete from submitting (or the TUEC  to consider) an application for the TUE prior to Sample  collection;   c) Due to national level prioritization of certain sports  or disciplines , the Athlete’s National Anti-Doping Organization did not permit or require the Athlete to apply for a prospective TUE (see comment to Article 5.1);  d) If an Anti -Doping Organization chooses to collect a Sample from an Athlete who is not an International -Level Athlete or National -Level Athlete, and that Athlete is Using a Prohibited Substance or Prohibited Method for Therapeutic  reasons, the Anti -Doping Organization must permit the Athlete to apply for a retroactive TUE ; or  e) The Athlete Used Out-of-Competition, for Therapeutic  reasons, a Prohibited Substance  that is only prohibited In-Competition.