4.3 WADA ’s Determination of the Prohibited List   WADA ’s determination of the Prohibited Substances  and Prohibited Methods that will be included on the Prohibited List , the classification of substances into categories on the Prohibited List , the classification of a substance as prohibited at all times or In-Competition  only, the classification of a substance or method as a Specified Substance, Specified Method  or Substance of Abuse  is final and shall not be subject to any challenge by an Athlete  or other Person  including, but not limited to, any challenge based on an argument that the substance or method was not a masking agent or did not have the potential to enhance performance, represent a health risk or violate the spirit of sport.4.4 Therapeutic Use Exemptions (“ TUE s”) 4.4.1  The presence of a Prohibited Substance  or its Metabolites  or Markers , and/ or the Use or Attempted  Use, Possession  or Administration  or Attempted  Administration  of a Prohibited Substance  or Prohibited Method , shall not be considered an anti-doping rule violation if it is consistent with the provisions of a TUE granted in accordance with the International Standard  for Therapeutic Use Exemptions.