If the Athlete  or other Person rebuts the preceding presumption by showing that a departure from the International Standard  for Laboratories occurred which could reasonably have caused the Adverse Analytical Finding , then IWF shall have the burden to establish that such departure did not cause the Adverse Analytical Finding .143.2.3  Departures from any other International Standard  or other anti-doping rule or policy set forth in the Code  or these Anti-Doping Rules shall not invalidate analytical results or other evidence of an anti-doping rule violation, and shall not constitute a defense to an anti-doping rule violation;15 provided, however, if the Athlete  or other Person  establishes that a departure from one of the specific International Standard  provisions listed below could reasonably have caused an anti-doping rule violation based on an Adverse Analytical Finding or whereabouts failure, then IWF shall have the burden to establish that such departure did not cause the Adverse Analytical Finding  or the whereabouts failure:(i)  a departure from the I nternational Standard for Testing and Investigations related to Sample  collection or Sample  handling which could reasonably have caused an anti-doping rule violation based on an Adverse Analytical Finding , in which case IWF shall have the burden to establish that such departure did not cause the Adverse Analytical Finding ;(ii)  a departure from the International Standard  for R esults Management or International Standard  for Testing  and Investigations related to an Adverse Passport Finding  which could reasonably have caused an anti-doping rule violation, in which case IWF shall have the burden to establish that such departure did not cause the anti-doping rule violation; (iii)  a departure from the International Standard  for Results Management related to the requirement to provide notice to the Athlete  of the B Sample opening which could reasonably have caused an anti-doping rule violation based on an Adverse Analytical Finding , in which case IWF shall have the burden to establish that such departure did not cause the Adverse Analytical Finding ;1614 [Comment to Article 3.2.2: The burden is on the Athlete or other Person to establish, by a balance of probability, a departure from the International Standard for Laboratories that could reasonably have caused the Adverse Analytical Finding.