These QC samples should include:  o QC low: Serum obtained from healthy individual(s), which is demonstrated to contain concentrations of IGF -I not greater than (≤) 200 ng/mL and P -III-NP not greater than (≤)  5 ng/mL;  o QC high: Serum  obtained from hGH  administration studies or another appropriate source that has been demonstrated to contain concentrations of IGF- I greater than (≥) 500 ng/mL and P -III-NP greater than (≥) 10 ng/mL.