4.4 Therapeutic Use Exemptions  (“TUEs ”)  4.4.1  The presence of a Prohibited Substance or its Metabolites or Markers , and/or the Use or Attemp ted Use , Possession or Administration or Attempted Administration of a Prohibited Substance or Prohibited Method , shall not be considered an anti -doping rule violation if it is consistent with the provisions of a TUE granted in accordance with the Internat ional Standard  for Therapeutic Use Exemptions .