• In the case of an ATPF -CPR for an abnormally high T/E ratio, GC/C/IRMS analysis is not mandatory when the confirmed T/E value is below the confirmation T/E cut -off calculated by the Adaptive Model  and provided within the ATPF -CPR notification received from ADAMS;  • For other CP  requests, when the steroid profile CP  does not confirm the ITP values that triggered the CP (e.g.