However, this definition shall not include the actions of bona fide medical personnel involving a Prohibited Substance  or Prohibited Method  Used  for genuine and legal therapeutic purposes or other acceptable justification and shall not include actions involving Prohibited Substances  which are not prohibited in Out-of-Competition  Testing  unless the circumstances as a whole demonstrate that such Prohibited Substances  are not intended for genuine and legal therapeutic purposes or are intended to enhance sport performance.Adverse Analytical Finding:  A report from a WADA -accredited laboratory or other WADA -approved laboratory that, consistent with the International Standard  for Laboratories, establishes in a Sample  the presence of a Prohibited Substance  or its Metabolites  or Markers  or evidence of the Use of a Prohibited Method .