- Target  Analyte (s) If the presence of more than one (1) Prohibited Substance , Metabolite (s) of a Prohibited Substance , or Marker (s) of the Use of a Prohibited Substance  or Prohibited  Method is detected  by the Initial Testing Procedure (s), the Laboratory  shall confirm as many of the Presumptive Adverse Analytical Findings  as reasonably possible (such decision should take into account the volume s available in the “A” and “B” Sample s).