4.4  Therapeutic Use Exemptions (“TUEs”)   4.4.1  The presence of a Prohibited Substance  or its Metabolites  or Markers, and/or the Use or Attempted Use , Possession  or Administration  or Attempted Administration  of a Prohibited Substance  or Prohibited Method , shall not be considered an anti-doping rule violation if it is consistent with the provisions of a TUE granted in accordance with the International Standard  for Therapeutic Use Exemptions .