If the Athlete  or other Person  rebuts the preceding presumption by showing that a departure fr om the International Standard  for Laboratories occurred which could reasonably have caused the Adverse Analytical Finding , then ILS shall have the burden to establish that such departure did not cause the Adverse Analytical Finding .14  3.2.3   Departures from any other International Standard  or other anti -doping rule or policy set forth in the Code  or these Anti -Doping  Rules shall not invalidate analytical results or other evidence of an anti -doping rule violation, and shall not constitute a def ense to an anti -doping rule violation;15 provided, however, if the Athlete  or other Person  establishes that a departure from one  of the specific International Standard  provisions listed below could reasonably have caused an anti-doping rule violation based  on an Adverse Analytical Finding  or whereabouts failure, then ILS shall have the burden to establish that such departure did not cause the Adverse Analytical Finding or the whereabouts failure:   (i)  a departure from the International Standard  for Testing  and Investigations related to Sample  collection or Sample  handling which could reasonably have caused an anti -doping rule violation based on an Adverse Analytical Finding , in which case ILS shall have the burden to establish that such departure did not cause the Adverse Analytical Finding ;   13  Comment to Article 3.2.1: For certain Prohibited Substances, WADA may instruct WADA -accredited lab oratories not to report Samples as an Adverse Analytical Finding if the estimated concentration of the Prohibited Substance or its Metabolites or Mar kers is below a Minimum Reporting Level.