4.4.4.2  An application to ILS for grant or recognition of a TUE must be made as soon as possible , save where Articles 4.1 or 4.3 of the International  20  Comment to Article 4.4.3: If ILS refuses to recognize a TUE granted by a National Anti -Doping Organization only because medical records or other information are missing that are needed to demonstrate satisfaction with the criteria in the International S tandard for Therapeutic Use Exemptions, the matter should not be referred to WADA.