TWIF  2021 Anti -Doping Rules  v1 Page 11 of 67     (i)  a departure from the International Standard  for Testing  and Investigations related to Sample  collection or Sample  handling which could reasonably have caused an anti -doping rule violation based on an Adverse Analytical Finding , in which case TWIF  shall have the burden to establish that such departure did not cause the Adverse Analytical Finding ;  (ii)  a departure fr om the International Standard  for Results Management  or International Standard  for Testing  and Investigations related to an Adverse Passport Finding  which could reasonably have caused an anti-doping  rule violation, in which case TWIF  shall have the burden to establish that such departure did not cause the anti -doping rule violation;   (iii)  a departure from the International Standard  for Results Management  related to the requirement to provide notic e to the Athlete  of the B Sample  opening which could reasonably have caused an anti -doping rule violation based on an Adverse Analytical Finding , in which case TWIF  shall have the burden to establish that such departure did not cause the Adverse Analytical  Finding ;16  (iv) a departure from the International Standard  for Results Management  related to Athlete  notification which could reasonably have caused an anti-doping rule violation based on a whereabouts failure, in which case TWIF  shall have the burden to establish that such departure did not cause the whereabouts failure.