return to the hotel was a happy one and therefore there was something to talk about. a new pot was shipped to replace the broken one. during the following six years his paper was rejected by three other journals. here are the facts on the matter. having access to thousands of books at your finger tips is magical! down syndrome is not caused by something the mother does (or does not do) during pregnancy. since both tests are offered on average every other month, there’s not really a “best time” to take them. 