'Send a standard library :class:`Request` to PyPI and return its
response.
:param req: The request to send.
:return: The HTTP response from PyPI (a standard library HTTPResponse).'

def send_request(self, req):

    handlers = []
    if self.password_handler:
        handlers.append(self.password_handler)
    if self.ssl_verifier:
        handlers.append(self.ssl_verifier)
    opener = build_opener(*handlers)
    return opener.open(req)
