( CNN ) You 'll see some familiar faces in the Final Four . Duke beat Gonzaga 66-52 on Sunday , giving Blue Devils ' coach Mike Krzyzewski his 12th trip to the semifinals of the NCAA men 's basketball tournament . Justise Winslow and Matt Jones each scored 16 to help Duke win the South Region . Gonzaga , led by 16 points from Kyle Wiltjer , was hoping to earn its first trip to the Final Four . Here 's how the Final Four , to be played in Indianapolis , has shaped up : . Next Saturday , Duke will face Michigan State in the first semifinal . In the next game , top seed Kentucky will battle Wisconsin . The winners will meet on Monday , April 6 , for the national championship . One other tournament game was played Sunday . Michigan State overcame Louisville 76-70 in overtime to win the East Region . The victory was sweet vindication for the Spartans , who had an up-and-down season and came into the East Region as a No . 7 seed . This will be the seventh Final Four for coach Tom Izzo , who led Michigan State to the national title in 2000 . Krzyzewski has won four national championships at Duke , which was the top seed in the South Region .
The Final Four matchups : Duke vs. Michigan State and Kentucky vs. Wisconsin . Duke beat Gonzaga on Sunday and Michigan State defeated Louisville in overtime .