Novak Djokovic gives the thumbs up at Indian Wells . Novak Djokovic progressed to the fourth round of the BNP Paribas Open at Indian Wells with a comfortable 7-5 6-3 victory over Albert Ramos-Vinolas . The world No 1 rarely looked troubled as he put together a straight sets triumph over Spaniard Ramos-Vinolas , who is yet to win an ATP Tour title . Djokovic , who would collect a 50th career gong should he defend his championship in the Coachella Valley , must now challenge home favourite John Isner for a place in the quarter-finals . The big-serving American fired down 18 aces as he found his way past Kevin Anderson 7-6 ( 8/6 ) 6-2 in a touch under one hour and 20 minutes . Fourth and fifth seeds Andy Murray and Kei Nishikori are safely through after overcoming Philipp Kohlschreiber and Fernando Verdasco respectively . Murray took a first set in 25 minutes but in the end needed the best part of two hours to overcome Kohlschreiber 6-1 3-6 6-1 while Japan 's Nishikori recovered from an early wobble to edge out Verdasco 6-7 ( 6/8 ) 6-1 6-4 . Awaiting Murray is Adrian Mannarino following the Frenchman 's 6-4 6-4 triumph over Ernests Gulbis and Nishikori 's next opponent is Feliciano Lopez . Djokovic rarely looked troubled as he beat Albert Ramos-Vinolas in straight sets . Ramos-Vinolas of Spain hits a backhand return against Djokovic but was unable to break the world No 1 . Jelena Djokovic , wife of the Serbia star , watches on during his match in California . The 12th seed from Spain was kept busy until the small hours but eventually completed a 6-2 4-6 6-3 victory over Pablo Cuevas of Uruguay . Also progressing in California were Bernard Tomic - the 7-5 6-4 conqueror of eighth seed David Ferrer - and surprise package Thanasi Kokkinakis . Australia 's world No 124 went the distance in a meeting with the experienced Juan Monaco that the 18-year-old won 6-2 5-7 7-6 ( 7/5 ) in nearly two hours and 47 minutes . In the women 's draw , second seed Maria Sharapova battled her way past fierce rival Victoria Azarenka to reach the last 16 . The Russian was inferior on her percentages throughout a bruising encounter between two multiple grand slam champions but nevertheless it was Azarenka who found herself saving five match points before succumbing to a 6-4 6-3 defeat . John Isner awaits Djokovic in the next round after the big-serving American beat Kevin Anderson . Maria Sharapova celebrates beating her fierce rival Victoria Azarenka to reach the last 16 . Next up for the world No 2 is a meeting with the defending champion , Flavia Pennetta of Italy , who dispatched Sam Stosur 6-4 6-2 . Making an early exit was fourth seed Caroline Wozniacki , the victim of a 6-4 6-4 win for Belinda Bencic , while Serbian hopeful Ana Ivanovic was eliminated 6-2 5-7 6-2 by Caroline Garcia . Eugenie Bouchard saw off Coco Vandeweghe 6-3 6-2 with qualifier Lesia Tsurenko ousting Alize Cornet 7-5 1-6 6-2 as Jelena Jankovic defeated Madison Keys 5-7 6-4 6-3 . Elsewhere , Sabine Lisicki of Germany called time on 11th seed Sara Errani 's campaign with a 6-4 6-2 triumph completed late on Monday night .
Novak Djokovic beat Albert Ramos-Vinolas at BNP Paribas Open . Wold No 1 beat Serb in straight sets , 7-5 6-3 . Spaniard is chasing his 50th career victory .